ACCELERATING PROMISING ONCOLOGY THERAPEUTICS INTO THE CLINIC THROUGH COLLABORATIVE DRUG DEVELOPMENT
USC Norris Comprehensive Cancer Center (USC Norris) is pleased to launch the Rosalie and Harold Rae Brown Center for Cancer Drug Development (CCDD) with a generous gift from the Rosalie and Harold Rae Brown Foundation. The CCDD employs an integrated academic-industry focused management model to engage investigators from different disciplines, collapse gaps in expertise, resources, and funding, and ensure that programs have a high likelihood of progressing to late Pre-Clinical stage development and submission of an Investigational New Drug (IND) application. Initial projects will be sharply focused on cancers that disproportionately affect members of the community for whom there are dramatic ethnic and racial disparities, such as breast cancer, prostate cancer and colorectal cancer, and blood cancers.
“This gift will have an immediate impact by transforming USC Norris discoveries of the underlying causes of cancer and disease progression into new treatments and clinical trials for our patients.”
The USC Norris CCDD drug development process is uniquely structured in partnership with faculty to accelerate a rigorous review of projects. This process will be managed by the MESH Academy Business Development and Industry Relations team to ensure transparency, establish a central point of contact, and reduce redundancies and missed opportunities.
Faculty complete Intake Form. This signals the first step in the review process.
Faculty will be paired with a MESH representative to:
No cookie cutter approach – each innovation is unique and requires iterative dialogue with faculty to engage and co-create a successful path to the clinic
How to Submit a Target to CCDD:
If you have any questions or would like to discuss your target/therapeutic before submitting the intake form, please contact the MESH BDIR team at firstname.lastname@example.org.
Faculty give short presentation, followed by Q&A.
EAC will rank each project based on 7 criteria:
EAC will provide list of prioritized targets with feedback to the CCDD Leadership team.
EAC will provide list of prioritized targets to advance
For targets that are advanced, faculty will work collaboratively with:
NCCC Director provides final decision on budget requests
Approved projects typically fall into one of these categories:
The MESH BDIR team will collaborate with the faculty/project team and with potential prospective external collaborators to formulate a partnering strategy that is mutually beneficial. The focus of the partnering zone is to:
For general questions or interests in partnering with the CCDD, please contact Vasiliki Anest, Business Director.
To learn more about giving to USC Norris, please contact Robert Weiner, Assistant Vice President of Development, at Robert.Weiner@med.usc.edu.