USC Norris Comprehensive Cancer Center

An NCI-designated Comprehensive Cancer Center

USC Norris Biorepositories

This platform provides  access to six biorepositories, each dedicated to advancing medical research and innovation. Additionally, we offer a link to our robust specimen catalog, developed in OpenSpecimen, where you can browse and request samples tailored to your study needs. 

The LAPCC prospectively collects, tracks, and analyzes biospecimens, clinical and demographic data, social and behavioral measures, patient-reported outcomes, and available radiographic scans from a multi-ethnic population of men with metastatic prostate cancer treated at Norris and LA General. Clinical data and biospecimens are collect at multiple time points throughout treatment on sequential lines of therapy. Prospectively collected specimens include blood (buffy coat, plasma, mononuclear cells / circulating tumor cells) and urine, as well stool samples in a subset of patients. Many of the patients also have archived tumor tissue specimens that were collected during their initial workup prior to enrolling in LAPCC; these tissue specimens are also accessible under the LAPCC consent.

PI: Amir Goldkorn, MD – agoldkor@med.usc.edu

LAPCC Specimen Catalog Link – https://keckbiobank.med.usc.edu/openspecimen/#/s/specimen-catalogs/5/dashboard



Aims to collect 1000 samples with longitudinal collection. Plasma and serum are stored. Clinical data and data on SDOH are also collected. We have an OpenSpecimen database linked to RedCap

PI : Bodour Salhia, PhD – salhia@usc.edu

BCSB catalog link-  https://keckbiobank.med.usc.edu/openspecimen/#/s/specimen-catalogs/6/search

The LA-FLFS is an observational study aims to elucidate multi-level factors associated with disease progression from fatty liver to more severe liver diseases. We perform liver imaging (fibroscan) and collect blood samples and questionnaire data from Hispanics and non-Hispanic white patients treated at Keck and LA General. Clinical data are also collected throughout the study period.  

MPI: V. Wendy Setiawan, PhD –vsetiawa@med.usc.edu, and Norah Terrault, MD,MPH –norah.terrault@med.usc.edu.

LA-FLFS catalog link – https://keckbiobank.med.usc.edu/openspecimen/#/s/specimen-catalogs/8/dashboard

Colorectal Cancer Cohort (CRCC), PI: Heinz-Josef Lenz, lenz@med.usc.edu: The Colorectal Cancer Cohort prospectively collects, tracks, and analyzes biospecimens, clinical and demographic data, social and behavioral measures, patient-reported outcomes of patient with stage II and III colorectal cancer and resected oligometastatic disease within 2 years of curative surgery treated at USC Norris and LA General. Clinical data and biospecimens are collected at multiple time points throughout treatment. Prospectively collected specimens include blood (buffy coat, plasma, mononuclear cells / circulating tumor cells) to test and validate a novel technology to identify minimal residual disease using methylated DNA in the blood. Recent data from Dr. Salhia lab (Co-PI on this protocol) demonstrated higher sensitivity than commercially available technology which can change the paradigm of how these patients are monitored and treated.  Many of the patients also have archived tumor tissue specimens that were collected during their initial workup prior to enrolling in LAPCC; these tissue specimens are also accessible under the protocol consent.

PI: Heinz-Josef Lenz, lenz@med.usc.edu

CRCC catalog –https://keckbiobank.med.usc.edu/openspecimen/#/s/specimen-catalogs/7/dashboard

PIs: Yali Dou and Abdullah Ladha, yali.dou@med.usc.edu and  Abdullah.Ladha@med.usc.edu.

The ALC prospectively collects, tracks, and analyzes biospecimens, clinical data, patient-reported outcomes, and available genomic information from a multi-ethnic population of patients with acute leukemia treated at Norris and LA General. Clinical data and biospecimens are collect at multiple time points at diagnosis and throughout treatment on sequential lines of therapy. Prospectively collected specimens include blood (plasma and mononuclear cells) and bone marrow buffy coat. These specimens are accessible upon written request to PIs and an approved study-specific IRB.