University of Southern California
USC/Norris Comprehensive Cancer Center
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Open Trials: THORAX


ProtocolDescriptionDetails
0S-08-9Short-Term Starvation Prior to Standard Chemotherapy with Gemcitabine and Cisplatin: Feasibility and Impact on Toxicity.

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Protocol Treatment Modalities:
Randomized: No
Principal Investigator(s):
Tanya Dorff
Staff Members:
Charlean Ketchens
Francisco Acosta
Lagrimas Ilagan
0S-09-4A Randomized Controlled Trial of Enoxaparin Thromboprophylaxis in Cancer Patients with Elevated Tissue Factor Bearing Microparticles.

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Protocol Treatment Modalities:
Other
Randomized: Yes
Principal Investigator(s):
Howard Liebman
Staff Members:
Laurie Hornor
Melissa Peralta
18M-07-1Phase II Study of AZD2171 (NSC#732208) in Patients with Malignant Mesothelioma.

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Protocol Treatment Modalities:
Anti-Angiogenesis
Randomized: No
Principal Investigator(s):
Barbara Gitlitz
Staff Members:
Charlean Ketchens
Eduardo Mejia
Gina Tse
Lagrimas Ilagan
2N-06-7A Multi-Center, Randomized, Double-Blind, Placebo-Controlled, Phase III Study of Single-Agent Tarceva (Erlotinib) Following Complete Tumor Resection with or without Adjuvant Chemotherapy in Patients with Stage IB-IIIA Non-Small Cell Lung Carcinoma who have EGFR-Positive Tumors.

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Protocol Treatment Modalities:
Biological Response Modifier
Randomized: Yes
Principal Investigator(s):
Barbara Gitlitz
Staff Members:
Charlean Ketchens
Gina Tse
Lagrimas Ilagan
Vatche Stepanian
2N-06-8A Multi-Center, Phase III, Randomized, Double-Blind, Placebo-Controlled Study of the Cancer Vaccine Stimuvax (L-BLP25 or BLP25 Liposome Vaccine) in Non-Small Cell Lung Cancer (NSCLC) Subjects with Unresectable Stage III Disease.

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Protocol Treatment Modalities:
Vaccine
Randomized: Yes
Principal Investigator(s):
Barbara Gitlitz
Staff Members:
Charlean Ketchens
Gina Tse
Lagrimas Ilagan
Vatche Stepanian
2N-08-1A Randomized, Double-Blind, Placebo-Controlled, Multi-Center, Phase II Study of the Efficacy and Safety of Apricoxib in Combination with Erlotinib in Non-Small Cell Lung Cancer Patients.

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Protocol Treatment Modalities:
Biological Response Modifier
Chemotherapy: Systemic
Randomized: Yes
Principal Investigator(s):
Barbara Gitlitz
Staff Members:
Charlean Ketchens
Eduardo Mejia
Gina Tse
Lagrimas Ilagan
2N-08-6Development of DNA Methylation Markers for Early Detection of Lung Cancer.

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Protocol Treatment Modalities:
Randomized: No
Principal Investigator(s):
Ite Laird
Staff Members:
Charlean Ketchens
Eduardo Mejia
Gina Tse
Lagrimas Ilagan
2O-08-3A Phase IB/II Trial of AMG 479 or AMG 102 in Combination with Platinum-Based Chemotherapy as First-Line Treatment for Extensive Stage Small Cell Lung Cancer.

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Protocol Treatment Modalities:
Chemotherapy: Systemic
Immunotherapy
Randomized: No
Principal Investigator(s):
Barbara Gitlitz
Staff Members:
Eduardo Mejia
Gina Tse
Lagrimas Ilagan
Xiomara Menendez
ctsu/E1505A Phase III Randomized Trial of Adjuvant Chemotherapy With or Without Bevacizumab for Patients With Completely Resected Stage IB (=/>4 cm) - IIIA Non-Small Cell Lung Cancer (NSCLC).

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Protocol Treatment Modalities:
Anti-Angiogenesis
Chemotherapy: Systemic
Randomized: Yes
Principal Investigator(s):
Barbara Gitlitz
Staff Members:
Charlean Ketchens
Gina Tse
Lagrimas Ilagan
Lynette Sebastian
RTOG-0517Randomized Phase III Trial to Evaluate RadioPharmaceuticals and Zoledronic Acid in the Palliation of Osteoblastic Metastases from Lung, Breast, and Prostate Cancer.

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Protocol Treatment Modalities:
Other
Randomized: Yes
Principal Investigator(s):
Parvesh Kumar
Staff Members:
Carryl Du Bois
SWOG-S0533A Pilot Trial of Cisplatin/Etoposide/Radiotherapy Followed by Consolidation Docetaxel and the Addition of Bevacizumab (NSC-704865) in Three Cohorts of Patients with Inoperable Locally Advanced Stage III Non-Small Cell Lung Cancer.

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Protocol Treatment Modalities:
Anti-Angiogenesis
Chemotherapy: Systemic
Radiation: External
Randomized: No
Principal Investigator(s):
Barbara Gitlitz
Staff Members:
Charlean Ketchens
Eduardo Mejia
Gina Tse
Lagrimas Ilagan
SWOG-S0720Phase II ERCC1 and RRM1-Based Adjuvant Therapy Trial in Patients with Stage I Non-Small Cell Lung Cancer (NSCLC).

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Protocol Treatment Modalities:
Chemotherapy: Systemic
Randomized: No
Principal Investigator(s):
Barbara Gitlitz
Staff Members:
Charlean Ketchens
Eduardo Mejia
Gina Tse
Lagrimas Ilagan
SWOG-S9925Lung Cancer Specimen Repository Protocol, Ancillary.

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Protocol Treatment Modalities:
Randomized: No
Principal Investigator(s):
Barbara Gitlitz
Staff Members:
Charlean Ketchens
Gina Tse
Lagrimas Ilagan
Vatche Stepanian
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Click on protocol number to see eligibility requirements

Protocol Treatment Modalities:
Autologous Bone Marrow Transplant
Biological Response Modifier
Chemotherapy: Local
Genetic
Randomized: Not Asked
Principal Investigator(s):
Lenny Africano
Lilia Frausto
Noemi Adalin
Staff Members:
Noemi Adalin