| Requirement |
1 | Any individual with multiple primary cancers |
2 | Any individual diagnosed with cancer under age 50 |
3 | Individuals with a known hereditary cancer syndrome |
4 | Individuals with features suggesting the diagnostic criteria for specific hereditary cancer syndromes |
5 | Individuals with two or more first or second degree relatives with cancer |
6 | Individuals from families where at least one family member was diagnosed with cancer under age 50 |