USC Norris Comprehensive Cancer Center

An NCI-designated Comprehensive Cancer Center

Alan S. Wayne, MD

Associate Director, Pediatric Oncology

Alan S. Wayne, M.D. is the Associate Director for Pediatric Oncology, Professor of Pediatrics and Medicine at the Keck School of Medicine of USC, the Director of the Cancer & Blood Disease Institute at Children’s Hospital Los Angeles (CHLA), and the Head of the Division of Hematology-Oncology in the Department of Pediatrics. In these roles, he oversees all research, treatment, prevention and education programs in pediatric hematology, oncology and hematopoietic stem cell transplantation at NCCC and CHLA.

Dr. Wayne’s primary research efforts are directed towards the development of new treatment approaches for leukemias and lymphomas with a focus on relapsed/refractory acute lymphoblastic leukemia. 

He develops and leads collaborative laboratory, translational and clinical investigations, including bench-to-bedside development of targeted, immune-based and cellular therapies. He serves as the Medical Director of the Therapeutic Advances in Childhood Leukemia/Lymphoma (TACL) Consortium, a multinational clinical trials group that conducts Phase I and II trials. He is also an international leader in the area of post-transplant relapse of hematologic malignancies, with the primary aim to study the biology, prevention and treatment of relapse after hematopoietic stem cell transplant.