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USC/Norris Comprehensive Cancer Center
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Publications for Norris Cancer Center Members in the Gastrointestinal Cancers Program

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Total Number of Publications: 822
Inter Programmatic Publications: 263
Intra Programmatic Publications: 61

1: Wu AH, Stram DO, C Pike M
RESPONSE: re: meta-analysis: dietary fat intake, serum estrogen levels, and the risk of breast cancer
J Natl Cancer Inst 92: 78A-78 ()
PM ID: 10620641
2: Grande F, Yamada R, Cao X, Aiello F, Garofalo A, Neamati N
Synthesis and biological evaluation of novel hydrazide based cytotoxic agents.
Expert Opin Investig Drugs 18: 555-68 ()
PM ID: 19388873
3: Lehman NL, Danenberg PV
Modulation of RTX cytotoxicity by thymidine and dipyridamole in vitro: implications for chemotherapy.
Cancer Chemother Pharmacol 45: 142-8 (2000)
PM ID: 10663629
4: Ziogas A, Gildea M, Cohen P, Bringman D, Taylor TH, Seminara D, Barker D, Casey GR, Haile R, Liao SY, Thomas DC, Noble B, Kurosaki T, Anton-Culver H
Cancer risk estimates for family members of a population-based family registry for breast and ovarian cancer.
Cancer Epidemiol Biomarkers Prev 9: 103-11 (2000)
PM ID: 10667470
5: Ohata M, Yamauchi M, Takeda K, Toda G, Kamimura S, Motomura K, Xiong S, Tsukamoto H
RAR and RXR expression by Kupffer cells.
Exp Mol Pathol 68: 13-20 (2000)
PM ID: 10640450
6: Tsao JL, Yatabe Y, Salovaara R, Järvinen HJ, Mecklin JP, Aaltonen LA, Tavaré S, Shibata D
Genetic reconstruction of individual colorectal tumor histories.
Proc Natl Acad Sci U S A 97: 1236-41 (2000)
PM ID: 10655514 PMC15581
7: Ireland AP, Shibata DK, Chandrasoma PT, Lord RV, Peters JH, DeMeester TR
Clinical significance of p53 mutations in adenocarcinoma of the esophagus and cardia.
Ann Surg 231: 179-87 (2000)
PM ID: 10674608 PMC1420984
8: Feng G, Kaplowitz N
Colchicine protects mice from the lethal effect of an agonistic anti-Fas antibody.
J Clin Invest 105: 329-39 (2000)
PM ID: 10675359 PMC377439
9: Kannan R, Chakrabarti R, Tang D, Kim KJ, Kaplowitz N
GSH transport in human cerebrovascular endothelial cells and human astrocytes: evidence for luminal localization of Na+-dependent GSH transport in HCEC.
Brain Res 852: 374-82 (2000)
PM ID: 10678765
10: Ingles SA, Garcia DG, Wang W, Nieters A, Henderson BE, Kolonel LN, Haile RW, Coetzee GA
Vitamin D receptor genotype and breast cancer in Latinas (United States).
Cancer Causes Control 11: 25-30 (2000)
PM ID: 10680726
11: Sirotnak FM, Danenberg KD, Chen J, Fritz F, Danenberg PV
Markedly decreased binding of vincristine to tubulin in vinca alkaloid-resistant Chinese hamster cells is associated with selective overexpression of alpha and beta tubulin isoforms.
Biochem Biophys Res Commun 269: 21-4 (2000)
PM ID: 10694470
12: Taktakishvili M, Neamati N, Pommier Y, Nair V
Recognition and inhibition of HIV integrase by a novel dinucleotide.
Bioorg Med Chem Lett 10: 249-51 (2000)
PM ID: 10698446
13: Pao MM, Liang G, Tsai YC, Xiong Z, Laird PW, Jones PA
DNA methylator and mismatch repair phenotypes are not mutually exclusive in colorectal cancer cell lines.
Oncogene 19: 943-52 (2000)
PM ID: 10702803
14: Wu AH
Diet and breast carcinoma in multiethnic populations.
Cancer 88: 1239-44 (2000)
PM ID: 10705361
15: Kaplowitz N
Mechanisms of liver cell injury.
J Hepatol 32: 39-47 (2000)
PM ID: 10728793
16: Eads CA, Danenberg KD, Kawakami K, Saltz LB, Blake C, Shibata D, Danenberg PV, Laird PW
MethyLight: a high-throughput assay to measure DNA methylation.
Nucleic Acids Res 28: E32 (2000)
PM ID: 10734209 PMC102836
17: Qin X, Shibata D, Gerson SL
Heterozygous DNA mismatch repair gene PMS2-knockout mice are susceptible to intestinal tumor induction with N-methyl-N-nitrosourea.
Carcinogenesis 21: 833-8 (2000)
PM ID: 10753224
18: Leder GH, Pillasch J, Kornmann M, Danenberg PV, Link KH
Theoretical considerations and in vitro concentration response studies with two human colorectal carcinoma cell lines. The rational experimental base for clinical studies in regional chemotherapy.
Gan To Kagaku Ryoho 27: 565-77 (2000)
PM ID: 10790999
19: Laird PW
Mouse models in DNA-methylation research.
Curr Top Microbiol Immunol 249: 119-34 (2000)
PM ID: 10802942
20: Iqbal S, Grimwade D, Chase A, Goldstone A, Burnett A, Goldman JM, Swirsky D
Identification of PML/RARalpha rearrangements in suspected acute promyelocytic leukemia using fluorescence in situ hybridization of bone marrow smears: a comparison with cytogenetics and RT-PCR in MRC ATRA trial patients. MRC Adult Leukaemia Working Party.
Leukemia 14: 950-3 (2000)
PM ID: 10803535
21: Conti PS, Keppler JS
New indications give PET a lift after struggle over regulatory and reimbursement issues.
Diagn Imaging (San Franc) 22: 40-7 (2000)
PM ID: 10848425
22: Lord RV, Salonga D, Danenberg KD, Peters JH, DeMeester TR, Park JM, Johansson J, Skinner KA, Chandrasoma PT, DeMeester SR, Bremner CG, Tsai PI, Danenberg PV
Telomerase reverse transcriptase expression is increased early in the Barrett's metaplasia, dysplasia, adenocarcinoma sequence.
J Gastrointest Surg 4: 135-42 (2000)
PM ID: 10675236
23: Mittur AV, Kaplowitz N, Kempner ES, Ookhtens M
Radiation inactivation studies of hepatic sinusoidal reduced glutathione transport system.
Biochim Biophys Acta 1464: 207-18 (2000)
PM ID: 10727608
24: Banerjee D, Gorlick R, Liefshitz A, Danenberg K, Danenberg PC, Danenberg PV, Klimstra D, Jhanwar S, Cordon-Cardo C, Fong Y, Kemeny N, Bertino JR
Levels of E2F-1 expression are higher in lung metastasis of colon cancer as compared with hepatic metastasis and correlate with levels of thymidylate synthase.
Cancer Res 60: 2365-7 (2000)
PM ID: 10811110
25: Wu AH, Stanczyk FZ, Hendrich S, Murphy PA, Zhang C, Wan P, Pike MC
Effects of soy foods on ovarian function in premenopausal women.
Br J Cancer 82: 1879-86 (2000)
PM ID: 10839307 PMC2363237
26: Mack TM, Deapen D, Hamilton AS
Representativeness of a roster of volunteer North American twins with chronic disease.
Twin Res 3: 33-42 (2000)
PM ID: 10808239
27: Tsukamoto H
Cyp2e1 and ALD.
Hepatology 32: 154-6 (2000)
PM ID: 10869305
28: Salonga D, Danenberg KD, Johnson M, Metzger R, Groshen S, Tsao-Wei DD, Lenz HJ, Leichman CG, Leichman L, Diasio RB, Danenberg PV
Colorectal tumors responding to 5-fluorouracil have low gene expression levels of dihydropyrimidine dehydrogenase, thymidylate synthase, and thymidine phosphorylase.
Clin Cancer Res 6: 1322-7 (2000)
PM ID: 10778957
29: Lu SC, Huang ZZ, Yang HT, Mato JM, Avila MA, Tsukamoto H
Changes in methionine adenosyltransferase and S-adenosylmethionine homeostasis in alcoholic rat liver.
Am J Physiol Gastrointest Liver Physiol 279: G178-85 (2000)
PM ID: 10898761
30: Ladner RD, Lynch FJ, Groshen S, Xiong YP, Sherrod AE, Caradonna SJ, Stoehlmacher J, Lenz HJ
dUTP nucleotidohydrolase isoform expression in normal and neoplastic tissues: association with survival and response to 5-fluorouracil in colorectal cancer.
Cancer Res 60: 3493-503 (2000)
PM ID: 10910061
31: Link KH, Kornmann M, Butzer U, Leder G, Sunelaitis E, Pillasch J, Salonga D, Danenberg KD, Danenberg PV, Beger HG
Thymidylate synthase quantitation and in vitro chemosensitivity testing predicts responses and survival of patients with isolated nonresectable liver tumors receiving hepatic arterial infusion chemotherapy.
Cancer 89: 288-96 (2000)
PM ID: 10918158
32: Tsao JL, Yatabe Y, Markl ID, Hajyan K, Jones PA, Shibata D
Bladder cancer genotype stability during clinical progression.
Genes Chromosomes Cancer 29: 26-32 (2000)
PM ID: 10918390
33: Webley SD, Hardcastle A, Ladner RD, Jackman AL, Aherne GW
Deoxyuridine triphosphatase (dUTPase) expression and sensitivity to the thymidylate synthase (TS) inhibitor ZD9331.
Br J Cancer 83: 792-9 (2000)
PM ID: 10952785 PMC2363540
34: Pluymers W, Neamati N, Pannecouque C, Fikkert V, Marchand C, Burke TR, Pommier Y, Schols D, De Clercq E, Debyser Z, Witvrouw M
Viral entry as the primary target for the anti-HIV activity of chicoric acid and its tetra-acetyl esters.
Mol Pharmacol 58: 641-8 (2000)
PM ID: 10953059
35: Bading JR, Shahinian AH, Bathija P, Conti PS
Pharmacokinetics of the thymidine analog 2'-fluoro-5-[(14)C]-methyl-1-beta-D-arabinofuranosyluracil ([(14)C]FMAU) in rat prostate tumor cells.
Nucl Med Biol 27: 361-8 (2000)
PM ID: 10938471
36: Eads CA, Lord RV, Kurumboor SK, Wickramasinghe K, Skinner ML, Long TI, Peters JH, DeMeester TR, Danenberg KD, Danenberg PV, Laird PW, Skinner KA
Fields of aberrant CpG island hypermethylation in Barrett's esophagus and associated adenocarcinoma.
Cancer Res 60: 5021-6 (2000)
PM ID: 11016622
37: Pommier Y, Marchand C, Neamati N
Retroviral integrase inhibitors year 2000: update and perspectives.
Antiviral Res 47: 139-48 (2000)
PM ID: 10974366
38: Bading JR, Alauddin MM, Fissekis JD, Shahinian AH, Joung J, Spector T, Conti PS
Blocking catabolism with eniluracil enhances PET studies of 5-[18F]fluorouracil pharmacokinetics.
J Nucl Med 41: 1714-24 (2000)
PM ID: 11038003
39: Mathurin P, Deng QG, Keshavarzian A, Choudhary S, Holmes EW, Tsukamoto H
Exacerbation of alcoholic liver injury by enteral endotoxin in rats.
Hepatology 32: 1008-17 (2000)
PM ID: 11050051
40: Tseng M, Greenberg ER, Sandler RS, Baron JA, Haile RW, Blumberg BS, McGlynn KA
Serum ferritin concentration and recurrence of colorectal adenoma.
Cancer Epidemiol Biomarkers Prev 9: 625-30 (2000)
PM ID: 10868699
41: Kolonel LN, Hankin JH, Whittemore AS, Wu AH, Gallagher RP, Wilkens LR, John EM, Howe GR, Dreon DM, West DW, Paffenbarger RS
Vegetables, fruits, legumes and prostate cancer: a multiethnic case-control study.
Cancer Epidemiol Biomarkers Prev 9: 795-804 (2000)
PM ID: 10952096
42: Miyahara T, Schrum LW, Rippe R, Xiong S, Yee HF, Motomura K, Anania FA, Willson TM, Tsukamoto H
Peroxisome proliferator-activated receptors and hepatic stellate cell activation.
J Biol Chem 275: 35715-22 (2000)
PM ID: 10969082
43: Sandler RS, Baron JA, Tosteson TD, Mandel JS, Haile RW
Rectal mucosal proliferation and risk of colorectal adenomas: results from a randomized controlled trial.
Cancer Epidemiol Biomarkers Prev 9: 653-6 (2001)
PM ID: 10919733
44: Levine AJ, Siegmund KD, Ervin CM, Diep AT, Lee ER, Frankl HD, Haile RW
The methylenetetrahydrofolate reductase 677C-->T polymorphism and distal colorectal adenoma risk.
Cancer Epidemiol Biomarkers Prev 9: 657-63 (2001)
PM ID: 10919734
45: Neamati N, Marchand C, Pommier Y
HIV-1 integrase inhibitors: past, present, and future.
Adv Pharmacol 49: 147-65 (2001)
PM ID: 11013763
46: Lang A, Schrum LW, Schoonhoven R, Tuvia S, Solís-Herruzo JA, Tsukamoto H, Brenner DA, Rippe RA
Expression of small heat shock protein alphaB-crystallin is induced after hepatic stellate cell activation.
Am J Physiol Gastrointest Liver Physiol 279: G1333-42 (2001)
PM ID: 11093957
47: Peto J, Mack TM
High constant incidence in twins and other relatives of women with breast cancer.
Nat Genet 26: 411-4 (2001)
PM ID: 11101836
48: Hamilton AS, Mack TM
Use of twins as mutual proxy respondents in a case-control study of breast cancer: effect of item nonresponse and misclassification.
Am J Epidemiol 152: 1093-103 (2001)
PM ID: 11117619
49: Shibata D, Aaltonen LA
Genetic predisposition and somatic diversification in tumor development and progression.
Adv Cancer Res 80: 83-114 (2001)
PM ID: 11034541
50: Wu AH, Yang D, Pike MC
A meta-analysis of soyfoods and risk of stomach cancer: the problem of potential confounders.
Cancer Epidemiol Biomarkers Prev 9: 1051-8 (2001)
PM ID: 11045787
51: Chen IJ, Neamati N, Nicklaus MC, Orr A, Anderson LA, Barchi JJ, Kelley JA, Pommier Y, MacKerell AD
Identification of HIV-1 integrase inhibitors via three-dimensional database searching using ASV and HIV-1 integrases as targets.
Bioorg Med Chem 8: 2385-98 (2001)
PM ID: 11058033
52: Kaplowitz N
Causality assessment versus guilt-by-association in drug hepatotoxicity.
Hepatology 33: 308-10 (2001)
PM ID: 11124850
53: Rose ML, Bradford BU, Germolec DR, Lin MW, Tsukamoto H, Thurman RG
Gadolinium chloride-induced hepatocyte proliferation is prevented by antibodies to tumor necrosis factor alpha.
Toxicol Appl Pharmacol 170: 39-45 (2001)
PM ID: 11141354
54: Langholz B, Richardson J, Rappaport EF, Waisman J, Cockburn MG, Mack TM
Skin characteristics and risk of superficial spreading and nodular melanoma (United States).
Cancer Causes Control 11: 741-50 (2001)
PM ID: 11065011
55: Kannan R, Ouyang B, Wawrousek EF, Kaplowitz N, Andley UP
Regulation of GSH in alphaA-expressing human lens epithelial cell lines and in alphaA knockout mouse lenses.
Invest Ophthalmol Vis Sci 42: 409-16 (2001)
PM ID: 11157875
56: Brabender J, Lenz HJ, Danenberg PV
[Molecular markers as basis for chemotherapy?]
Chirurg 71: 1433-9 (2001)
PM ID: 11195061
57: Formenti SC, Felix J, Salonga D, Danenberg K, Pike MC, Danenberg P
Expression of metastases-associated genes in cervical cancers resected in the proliferative and secretory phases of the menstrual cycle.
Clin Cancer Res 6: 4653-7 (2001)
PM ID: 11156216
58: Iqbal S, Lenz HJ
Determinants of prognosis and response to therapy in colorectal cancer.
Curr Oncol Rep 3: 102-8 (2001)
PM ID: 11177741
59: Lord RV, Tsai PI, Danenberg KD, Peters JH, DeMeester TR, Tsao-Wei DD, Groshen S, Salonga D, Park JM, Crookes PF, Kiyabu M, Chandrasoma PT, Danenberg PV
Retinoic acid receptor-alpha messenger RNA expression is increased and retinoic acid receptor-gamma expression is decreased in Barrett's intestinal metaplasia, dysplasia, adenocarcinoma sequence.
Surgery 129: 267-76 (2001)
PM ID: 11231454
60: Cortessis V, Siegmund KD, Chen QR, Zhou N, Diep AT, Frankl H, Lee EJ, Zhu QS, Haile R, Levy D
A case-control study of microsomal epoxide hydrolase, smoking, meat consumption, glutathione S-transferase M3, and risk of colorectal adenomas.
Cancer Res 61: 2381-5 (2001)
PM ID: 11289100
61: Kuehne J, Biernacki P, Kleisli T, Streeter O, Beart RW
Continence Preservation in the Management of Recurrent Rectal Cancer: Booth P25.
Dis Colon Rectum 44: A27-A59 (2001)
PM ID: 11373539
62: Kawakami K, Brabender J, Lord RV, Groshen S, Greenwald BD, Krasna MJ, Yin J, Fleisher AS, Abraham JM, Beer DG, Sidransky D, Huss HT, DeMeester TR, Eads CA, Laird PW, Ilson DH, Kelsen DP, Harpole DH, Moore MB, Danenberg KD, Danenberg PV, Meltzer SJ
Hypermethylated APC DNA in plasma and prognosis of patients with esophageal adenocarcinoma.
J Natl Cancer Inst 92: 1805-11 (2001)
PM ID: 11078757
63: Eads CA, Lord RV, Wickramasinghe K, Long TI, Kurumboor SK, Bernstein L, Peters JH, DeMeester SR, DeMeester TR, Skinner KA, Laird PW
Epigenetic patterns in the progression of esophageal adenocarcinoma.
Cancer Res 61: 3410-8 (2001)
PM ID: 11309301
64: Grem JL, Danenberg KD, Behan K, Parr A, Young L, Danenberg PV, Nguyen D, Drake JA, Monks A, Allegra CJ
Thymidine kinase, thymidylate synthase, and dihydropyrimidine dehydrogenase profiles of cell lines of the National Cancer Institute's Anticancer Drug Screen.
Clin Cancer Res 7: 999-1009 (2001)
PM ID: 11309351
65: Blake C, Tsao JL, Wu AH, Shibata D
Stepwise deletions of polyA sequences in mismatch repair-deficient colorectal cancers.
Am J Pathol 158: 1867-70 (2001)
PM ID: 11337385 PMC1891934
66: Cockburn MG, Hamilton A, Mack TM
Recall bias in self-reported melanoma risk factors.
Am J Epidemiol 153: 1021-6 (2001)
PM ID: 11384959
67: Vilkki S, Tsao JL, Loukola A, Pöyhönen M, Vierimaa O, Herva R, Aaltonen LA, Shibata D
Extensive somatic microsatellite mutations in normal human tissue.
Cancer Res 61: 4541-4 (2001)
PM ID: 11389087
68: Hsieh CL, Oakley-Girvan I, Balise RR, Halpern J, Gallagher RP, Wu AH, Kolonel LN, O'Brien LE, Lin IG, Van Den Berg DJ, Teh CZ, West DW, Whittemore AS
A genome screen of families with multiple cases of prostate cancer: evidence of genetic heterogeneity.
Am J Hum Genet 69: 148-58 (2001)
PM ID: 11404817 PMC1226029
69: Kaplowitz N
Cell death at the millennium. Implications for liver diseases.
Clin Liver Dis 4: 1-23, v (2001)
PM ID: 11232179
70: Brabender J, Lord RV, Danenberg KD, Metzger R, Schneider PM, Uetake H, Kawakami K, Park JM, Salonga D, Peters JH, DeMeester TR, Hölscher AH, Danenberg PV
Upregulation of ornithine decarboxylase mRNA expression in Barrett's esophagus and Barrett's-associated adenocarcinoma.
J Gastrointest Surg 5: 174-81; discussion 182 (2001)
PM ID: 11331481
71: Gan Y, Mo Y, Kalns JE, Lu J, Danenberg K, Danenberg P, Wientjes MG, Au JL
Expression of DT-diaphorase and cytochrome P450 reductase correlates with mitomycin C activity in human bladder tumors.
Clin Cancer Res 7: 1313-9 (2001)
PM ID: 11350900
72: Wu AH, Whittemore AS, Kolonel LN, Stanczyk FZ, John EM, Gallagher RP, West DW
Lifestyle determinants of 5alpha-reductase metabolites in older African-American, white, and Asian-American men.
Cancer Epidemiol Biomarkers Prev 10: 533-8 (2001)
PM ID: 11352865
73: Tsukamoto H, Lu SC
Current concepts in the pathogenesis of alcoholic liver injury.
FASEB J 15: 1335-49 (2001)
PM ID: 11387231
74: Mack TM
The new pan-Asian paan problem.
Lancet 357: 1638-9 (2001)
PM ID: 11425364
75: Brabender J, Usadel H, Danenberg KD, Metzger R, Schneider PM, Lord RV, Wickramasinghe K, Lum CE, Park JM, Salonga D, Singer JB, Sidransky D, Hölscher AH, Meltzer SJ, Danenberg PV
Adenomatous polyposis coli gene promoter hypermethylation in non-small cell lung cancer is associated with survival.
Oncogene 20: 3528-32 (2001)
PM ID: 11429699
76: Neamati N
Structure-based HIV-1 integrase inhibitor design: a future perspective.
Expert Opin Investig Drugs 10: 281-96 (2001)
PM ID: 11178341
77: Shibata D
Talking tumours: histories from sequences.
Ann Med 33: 148-52 (2001)
PM ID: 11327118
78: Anton PA, Poles MA, Elliott J, Mao SH, McGowan I, Lenz HJ, Chen IS
Sensitive and reproducible quantitation of mucosal HIV-1 RNA and DNA viral burden in patients with detectable and undetectable plasma viral HIV-1 RNA using endoscopic biopsies.
J Virol Methods 95: 65-79 (2001)
PM ID: 11377714
79: Keppler JS, Conti PS
A cost analysis of positron emission tomography.
AJR Am J Roentgenol 177: 31-40 (2001)
PM ID: 11418393
80: Wajed SA, Laird PW, DeMeester TR
DNA methylation: an alternative pathway to cancer.
Ann Surg 234: 10-20 (2001)
PM ID: 11420478 PMC1421942
81: Xiong Z, Wu AH, Bender CM, Tsao JL, Blake C, Shibata D, Jones PA, Yu MC, Ross RK, Laird PW
Mismatch repair deficiency and CpG island hypermethylation in sporadic colon adenocarcinomas.
Cancer Epidemiol Biomarkers Prev 10: 799-803 (2001)
PM ID: 11440966
82: Xu Z, Choi J, Yen TS, Lu W, Strohecker A, Govindarajan S, Chien D, Selby MJ, Ou JJ
Synthesis of a novel hepatitis C virus protein by ribosomal frameshift.
EMBO J 20: 3840-8 (2001)
PM ID: 11447125 PMC125543
83: Garcia AA, Leichman CG, Lenz HJ, Baranda J, Lujan R, Casagrande Y, Leichman L
Phase II trial of outpatient schedule of paclitaxel in patients with previously untreated metastatic, measurable adenocarcinoma of the stomach.
Jpn J Clin Oncol 31: 275-8 (2001)
PM ID: 11463806
84: Brabender J, Lord RV, Danenberg KD, Metzger R, Schneider PM, Park JM, Salonga D, Groshen S, Tsao-Wei DD, DeMeester TR, Hölscher AH, Danenberg PV
Increased c-myb mRNA expression in Barrett's esophagus and Barrett's-associated adenocarcinoma.
J Surg Res 99: 301-6 (2001)
PM ID: 11469901
85: Markl ID, Cheng JP, Liang G, Shibata D, Laird PW, Jones PA
Global and gene-specific epigenetic patterns in human bladder cancer genomes are relatively stable in vivo and in vitro over time.
Cancer Res 61: 5875-84 (2001)
PM ID: 11479229
86: Lara PN, Gandara DR, Longmate J, Gumerlock PH, Lau DH, Edelman MJ, Gandour-Edwards R, Mack PC, Israel V, Raschko J, Frankel P, Perez EA, Lenz HJ, Doroshow JH
Activity of high-dose toremifene plus cisplatin in platinum-treated non-small-cell lung cancer: a phase II California Cancer Consortium Trial.
Cancer Chemother Pharmacol 48: 22-8 (2001)
PM ID: 11488520
87: Taktakishvili M, Neamati N, Pommier Y, Nair V
Discovery of a nuclease-resistant, non-natural dinucleotide that inhibits HIV-1 integrase.
Bioorg Med Chem Lett 11: 1433-5 (2001)
PM ID: 11378371
88: Tsukamoto H, Takei Y, McClain CJ, Joshi-Barve S, Hill DA, Schmidt J, Deaciuc I, Barve S, Colell A, Garcia-Ruiz C, Kaplowitz N, Fernandez-Checa JC, Yokoyama H, Okamura Y, Nakamura Y, Ishii H, Chawla RK, Barve S, Joshi-Barve S, Watson W, Nelson W, Lin MW, Ohata M, Motomura K, Enomoto N, Ikejima K, Kitamura T, Oide H, Hirose M, Bradford BU, Rivera CA, Kono H, Peter S, Yamashina S, Konno A, Ishikawa M, Shimizu H, Sato N, Thurman R
How is the liver primed or sensitized for alcoholic liver disease?
Alcohol Clin Exp Res 25: 171S-181S (2001)
PM ID: 11391068
89: Crabb DW, Pinairs J, Hasanadka R, Fang M, Leo MA, Lieber CS, Tsukamoto H, Motomura K, Miyahara T, Ohata M, Bosron W, Sanghani S, Kedishvili N, Shiraishi H, Yokoyama H, Miyagi M, Ishii H, Bergheim I, Menzl I, Parlesak A, Bode C
Alcohol and retinoids.
Alcohol Clin Exp Res 25: 207S-217S (2001)
PM ID: 11391073
90: Tetef ML, Synold TW, Chow WA, Leong LA, Margolin K, Morgan RJ, Raschko J, Shibata SI, Somlo G, Yen Y, Groshen S, Johnson KC, Lenz HJ, Gandara D, Doroshow JH
Phase I trial of 96-hour continuous infusion of dexrazoxane in patients with advanced malignancies.
Clin Cancer Res 7: 1569-76 (2001)
PM ID: 11410492
91: Zhang XK, Neamati N, Lee YK, Orr A, Brown RD, Whitaker N, Pommier Y, Burke TR
Arylisothiocyanate-containing esters of caffeic acid designed as affinity ligands for HIV-1 integrase.
Bioorg Med Chem 9: 1649-57 (2001)
PM ID: 11425564
92: Marchand C, Neamati N, Pommier Y
In vitro human immunodeficiency virus type 1 integrase assays.
Methods Enzymol 340: 624-33 (2001)
PM ID: 11494874
93: Motomura K, Ohata M, Satre M, Tsukamoto H
Destabilization of TNF-alpha mRNA by retinoic acid in hepatic macrophages: implications for alcoholic liver disease.
Am J Physiol Endocrinol Metab 281: E420-9 (2001)
PM ID: 11500296
94: Li JZ, Ou JH
Differential regulation of hepatitis B virus gene expression by the Sp1 transcription factor.
J Virol 75: 8400-6 (2001)
PM ID: 11507185 PMC115085
95: Fu CH, Martin-Aragon S, Weinberg KI, Ardi VC, Danenberg PV, Avramis VI
Reversal of cytosine arabinoside (ara-C) resistance by the synergistic combination of 6-thioguanine plus ara-C plus PEG-asparaginase (TGAP) in human leukemia lines lacking or expressing p53 protein.
Cancer Chemother Pharmacol 48: 123-33 (2001)
PM ID: 11561778
96: Brabender J, Danenberg KD, Metzger R, Schneider PM, Park JM, Salonga D, Hölscher AH, Danenberg PV
Epidermal growth factor receptor and HER2-neu mRNA expression in non-small cell lung cancer Is correlated with survival.
Clin Cancer Res 7: 1850-5 (2001)
PM ID: 11448895
97: Spear MA, Breakefield XO, Beltzer J, Schuback D, Weissleder R, Pardo FS, Ladner RD
Isolation, characterization, and recovery of small peptide phage display epitopes selected against viable malignant glioma cells.
Cancer Gene Ther 8: 506-11 (2001)
PM ID: 11498772
98: Wang W, Xue S, Ingles SA, Chen QR, Diep AT, Frankl HD, Stolz A, Haile RW
An association between genetic polymorphisms in the ileal sodium-dependent bile acid transporter gene and the risk of colorectal adenomas.
Cancer Epidemiol Biomarkers Prev 10: 931-6 (2001)
PM ID: 11535543
99: Tsen HF, Morgenstern H, Mack TM, Peters RK
Risk factors for penile cancer: results of a population-based case-control study in Los Angeles County (United States).
Cancer Causes Control 12: 267-77 (2001)
PM ID: 11405332
100: Kaplowitz N
Drug-induced liver disorders: implications for drug development and regulation.
Drug Saf 24: 483-90 (2001)
PM ID: 11444721
101: Wu AH, Shibata D, Yu MC, Lai MY, Ross RK
Dietary heterocyclic amines and microsatellite instability in colon adenocarcinomas.
Carcinogenesis 22: 1681-4 (2001)
PM ID: 11577009
102: Chan MF, van Amerongen R, Nijjar T, Cuppen E, Jones PA, Laird PW
Reduced rates of gene loss, gene silencing, and gene mutation in Dnmt1-deficient embryonic stem cells.
Mol Cell Biol 21: 7587-600 (2001)
PM ID: 11604495 PMC99930
103: Cockburn MG, Hamilton AS, Zadnick J, Cozen W, Mack TM
Development and representativeness of a large population-based cohort of native Californian twins.
Twin Res 4: 242-50 (2001)
PM ID: 11665304
104: Colell A, Coll O, García-Ruiz C, París R, Tiribelli C, Kaplowitz N, Fernández-Checa JC
Tauroursodeoxycholic acid protects hepatocytes from ethanol-fed rats against tumor necrosis factor-induced cell death by replenishing mitochondrial glutathione.
Hepatology 34: 964-71 (2001)
PM ID: 11679967
105: Alauddin MM, Shahinian A, Gordon EM, Bading JR, Conti PS
Preclinical evaluation of the penciclovir analog 9-(4-[(18)F]fluoro-3-hydroxymethylbutyl)guanine for in vivo measurement of suicide gene expression with PET.
J Nucl Med 42: 1682-90 (2001)
PM ID: 11696640
106: Stoehlmacher J, Ghaderi V, Iobal S, Groshen S, Tsao-Wei DD, Park DJ, Lenz HJ
A polymorphism of the XRCC1 gene predicts for response to platinum based treatment in advanced colorectal cancer.
Anticancer Res 21: 3075-9 (2001)
PM ID: 11712813
107: Shirota Y, Stoehlmacher J, Brabender J, Xiong YP, Uetake H, Danenberg KD, Groshen S, Tsao-Wei DD, Danenberg PV, Lenz HJ
ERCC1 and thymidylate synthase mRNA levels predict survival for colorectal cancer patients receiving combination oxaliplatin and fluorouracil chemotherapy.
J Clin Oncol 19: 4298-304 (2001)
PM ID: 11731512
108: Melek M, Jones JM, O'Dea MH, Pais GC, Burke TR, Pommier Y, Neamati N, Gellert M
Effect of HIV integrase inhibitors on the RAG1/2 recombinase.
Proc Natl Acad Sci U S A 99: 134-7 (2001)
PM ID: 11756686 PMC117527
109: Ingles SA, Wang JG, Coetzee GA, Lee ER, Frankl HD, Haile RW
Vitamin D receptor polymorphisms and risk of colorectal adenomas (United States).
Cancer Causes Control 12: 607-14 (2002)
PM ID: 11552708
110: Cockburn MG, Black W, McKelvey W, Mack TM
Determinants of melanoma in a case-control study of twins (United States).
Cancer Causes Control 12: 615-25 (2002)
PM ID: 11552709
111: Wu AH, Wan P, Bernstein L
A multiethnic population-based study of smoking, alcohol and body size and risk of adenocarcinomas of the stomach and esophagus (United States).
Cancer Causes Control 12: 721-32 (2002)
PM ID: 11562112
112: Tatlidil R, Conti PS, Conti PS
Gastric and colonic bypass grafts: FDG positron emission tomographic patterns.
Clin Nucl Med 26: 955-6 (2002)
PM ID: 11595859
113: Park DJ, Stoehlmacher J, Zhang W, Tsao-Wei DD, Groshen S, Lenz HJ
A Xeroderma pigmentosum group D gene polymorphism predicts clinical outcome to platinum-based chemotherapy in patients with advanced colorectal cancer.
Cancer Res 61: 8654-8 (2002)
PM ID: 11751380
114: Liang G, Chan MF, Tomigahara Y, Tsai YC, Gonzales FA, Li EM, Laird PW, Jones PA
Cooperativity between DNA methyltransferases in the maintenance methylation of repetitive elements.
Mol Cell Biol 22: 480-91 (2002)
PM ID: 11756544 PMC139739
115: Marchand C, Zhang XK, Pais GC, Cowansage K, Neamati N, Burke TR, Pommier Y
Structural determinants for HIV-1 integrase inhibition by beta-diketo acids.
J Biol Chem 277: 12596-603 (2002)
PM ID: 11805103
116: Usadel H, Brabender J, Danenberg KD, Jerónimo C, Harden S, Engles J, Danenberg PV, Yang S, Sidransky D
Quantitative adenomatous polyposis coli promoter methylation analysis in tumor tissue, serum, and plasma DNA of patients with lung cancer.
Cancer Res 62: 371-5 (2002)
PM ID: 11809682
117: Mittur A, Wolkoff AW, Kaplowitz N
The thiol sensitivity of glutathione transport in sidedness-sorted basolateral liver plasma membrane and in Oatp1-expressing HeLa cell membrane.
Mol Pharmacol 61: 425-35 (2002)
PM ID: 11809868
118: Kawakami K, Salonga D, Park JM, Danenberg KD, Uetake H, Brabender J, Omura K, Watanabe G, Danenberg PV
Different lengths of a polymorphic repeat sequence in the thymidylate synthase gene affect translational efficiency but not its gene expression.
Clin Cancer Res 7: 4096-101 (2002)
PM ID: 11751507
119: Neamati N
A small-molecule antagonist of virion assembly.
Expert Opin Investig Drugs 10: 1767-70 (2002)
PM ID: 11785455
120: Xu Z, Yen TS, Wu L, Madden CR, Tan W, Slagle BL, Ou JH
Enhancement of hepatitis B virus replication by its X protein in transgenic mice.
J Virol 76: 2579-84 (2002)
PM ID: 11836439 PMC153824
121: Wagner HN, Wiseman GA, Marcus CS, Nabi HA, Nagle CE, Fink-Bennett DM, Lamonica DM, Conti PS
Administration guidelines for radioimmunotherapy of non-Hodgkin's lymphoma with (90)Y-labeled anti-CD20 monoclonal antibody.
J Nucl Med 43: 267-72 (2002)
PM ID: 11850494
122: Laiho P, Launonen V, Lahermo P, Esteller M, Guo M, Herman JG, Mecklin JP, Järvinen HJ, Sistonen P, Kim KM, Shibata D, Houlston RS, Aaltonen LA
Low-level microsatellite instability in most colorectal carcinomas.
Cancer Res 62: 1166-70 (2002)
PM ID: 11861399
123: Borugian MJ, Sheps SB, Whittemore AS, Wu AH, Potter JD, Gallagher RP
Carbohydrates and colorectal cancer risk among Chinese in North America.
Cancer Epidemiol Biomarkers Prev 11: 187-93 (2002)
PM ID: 11867506
124: Formenti SC, Spicer D, Skinner KA, Cohen D, Groshen S, Bettini AC, Naritoku WY, Press MF, Salonga D, Tsao-Wei DD, Danenberg K, Danenberg P
Low HER2/neu gene expression is associated with pathological response to concurrent paclitaxel and radiation therapy in locally advanced breast cancer.
Int J Radiat Oncol Biol Phys 52: 397-405 (2002)
PM ID: 11872285
125: Wu AH
Soy and risk of hormone-related and other cancers.
Adv Exp Med Biol 492: 19-28 (2002)
PM ID: 11480666
126: Ness RB, Cramer DW, Goodman MT, Kjaer SK, Mallin K, Mosgaard BJ, Purdie DM, Risch HA, Vergona R, Wu AH
Infertility, fertility drugs, and ovarian cancer: a pooled analysis of case-control studies.
Am J Epidemiol 155: 217-24 (2002)
PM ID: 11821246
127: Brabender J, Park JM, Metzger R, Schneider PM, Lord RV, Hölscher AH, Danenberg KD, Danenberg PV
Prognostic significance of cyclooxygenase 2 mRNA expression in non-small cell lung cancer.
Ann Surg 235: 440-3 (2002)
PM ID: 11882767 PMC1422451
128: Eads CA, Nickel AE, Laird PW
Complete genetic suppression of polyp formation and reduction of CpG-island hypermethylation in Apc(Min/+) Dnmt1-hypomorphic Mice.
Cancer Res 62: 1296-9 (2002)
PM ID: 11888894
129: Pullarkat ST, Stoehlmacher J, Ghaderi V, Xiong YP, Ingles SA, Sherrod AE, Warren R, Tsao-Wei DD, Groshen S, Lenz HJ
Thymidylate synthase gene polymorphism determines response and toxicity of 5-FU chemotherapy.
Pharmacogenomics J 1: 65-70 (2002)
PM ID: 11913730
130: Stram DO, Huberman M, Wu AH
Is residual confounding a reasonable explanation for the apparent protective effects of beta-carotene found in epidemiologic studies of lung cancer in smokers?
Am J Epidemiol 155: 622-8 (2002)
PM ID: 11914189
131: Müller-Ehmsen J, Peterson KL, Kedes L, Whittaker P, Dow JS, Long TI, Laird PW, Kloner RA
Rebuilding a damaged heart: long-term survival of transplanted neonatal rat cardiomyocytes after myocardial infarction and effect on cardiac function.
Circulation 105: 1720-6 (2002)
PM ID: 11940553
132: Karagas MR, Stukel TA, Dykes J, Miglionico J, Greene MA, Carey M, Armstrong B, Elwood JM, Gallagher RP, Green AC, Holly EA, Kirkpatrick CS, Mack TM, Østerlind A, Rosso S, Swerdlow AJ
A pooled analysis of 10 case-control studies of melanoma and oral contraceptive use.
Br J Cancer 86: 1085-92 (2002)
PM ID: 11953854 PMC2364185
133: Levine AJ, Harper JM, Ervin CM, Chen YH, Harmon E, Xue S, Lee ER, Frankel HD, Haile RW
Serum 25-hydroxyvitamin D, dietary calcium intake, and distal colorectal adenoma risk.
Nutr Cancer 39: 35-41 (2002)
PM ID: 11588900
134: Kanzaki A, Toi M, Neamati N, Miyashita H, Oubu M, Nakayama K, Bando H, Ogawa K, Mutoh M, Mori S, Terada K, Sugiyama T, Fukumoto M, Takebayashi Y
Copper-transporting P-type adenosine triphosphatase (ATP7B) is expressed in human breast carcinoma.
Jpn J Cancer Res 93: 70-7 (2002)
PM ID: 11802810
135: Stoehlmacher J, Ingles SA, Park DJ, Zhang W, Lenz HJ
The -9Ala/-9Val polymorphism in the mitochondrial targeting sequence of the manganese superoxide dismutase gene (MnSOD) is associated with age among Hispanics with colorectal carcinoma.
Oncol Rep 9: 235-8 (2002)
PM ID: 11836586
136: Brabender J, Danenberg KD, Metzger R, Schneider PM, Lord RV, Groshen S, Tsao-Wei DD, Park JM, Salonga D, Hölscher AH, Danenberg PV
The role of retinoid X receptor messenger RNA expression in curatively resected non-small cell lung cancer.
Clin Cancer Res 8: 438-43 (2002)
PM ID: 11839661
137: Trinh BN, Long TI, Laird PW
DNA methylation analysis by MethyLight technology.
Methods 25: 456-62 (2002)
PM ID: 11846615
138: Trinh BN, Long TI, Nickel AE, Shibata D, Laird PW
DNA methyltransferase deficiency modifies cancer susceptibility in mice lacking DNA mismatch repair.
Mol Cell Biol 22: 2906-17 (2002)
PM ID: 11940649 PMC133764
139: Kim KM, Salovaara R, Mecklin JP, Järvinen HJ, Aaltonen LA, Shibata D
PolyA deletions in hereditary nonpolyposis colorectal cancer: mutations before a gatekeeper.
Am J Pathol 160: 1503-6 (2002)
PM ID: 11943734 PMC1867223
140: Feng G, Kaplowitz N
Mechanism of staurosporine-induced apoptosis in murine hepatocytes.
Am J Physiol Gastrointest Liver Physiol 282: G825-34 (2002)
PM ID: 11960779
141: Mathurin P, Xiong S, Kharbanda KK, Veal N, Miyahara T, Motomura K, Rippe RA, Bachem MG, Tsukamoto H
IL-10 receptor and coreceptor expression in quiescent and activated hepatic stellate cells.
Am J Physiol Gastrointest Liver Physiol 282: G981-90 (2002)
PM ID: 12016123
142: Yamaga AK, Ou JH
Membrane topology of the hepatitis C virus NS2 protein.
J Biol Chem 277: 33228-34 (2002)
PM ID: 12082096
143: Müller-Ehmsen J, Whittaker P, Kloner RA, Dow JS, Sakoda T, Long TI, Laird PW, Kedes L
Survival and development of neonatal rat cardiomyocytes transplanted into adult myocardium.
J Mol Cell Cardiol 34: 107-16 (2002)
PM ID: 11851351
144: Kaplowitz N
Biochemical and cellular mechanisms of toxic liver injury.
Semin Liver Dis 22: 137-44 (2002)
PM ID: 12016545
145: Li JZ, Xu Z, Zheng YT, Johnson DL, Ou JH
Regulation of hepatocyte nuclear factor 1 activity by wild-type and mutant hepatitis B virus X proteins.
J Virol 76: 5875-81 (2002)
PM ID: 12021320 PMC136206
146: Stoehlmacher J, Park DJ, Zhang W, Groshen S, Tsao-Wei DD, Yu MC, Lenz HJ
Association between glutathione S-transferase P1, T1, and M1 genetic polymorphism and survival of patients with metastatic colorectal cancer.
J Natl Cancer Inst 94: 936-42 (2002)
PM ID: 12072547
147: Falk RT, Fears TR, Hoover RN, Pike MC, Wu AH, Nomura AM, Kolonel LN, West DW, Ziegler RG
Does place of birth influence endogenous hormone levels in Asian-American women?
Br J Cancer 87: 54-60 (2002)
PM ID: 12085256 PMC2364275
148: Nagai H, Matsumaru K, Feng G, Kaplowitz N
Reduced glutathione depletion causes necrosis and sensitization to tumor necrosis factor-alpha-induced apoptosis in cultured mouse hepatocytes.
Hepatology 36: 55-64 (2002)
PM ID: 12085349
149: Goodman MT, Wu AH, Tung KH, McDuffie K, Kolonel LN, Nomura AM, Terada K, Wilkens LR, Murphy ST, Hankin JH
Association of dairy products, lactose, and calcium with the risk of ovarian cancer.
Am J Epidemiol 156: 148-57 (2002)
PM ID: 12117706
150: Trinh BN, Ong CN, Coetzee GA, Yu MC, Laird PW
Thymidylate synthase: a novel genetic determinant of plasma homocysteine and folate levels.
Hum Genet 111: 299-302 (2002)
PM ID: 12215845
151: Lin HJ, Zhou H, Dai A, Huang HF, Lin JH, Frankl HD, Lee ER, Haile RW
Glutathione transferase GSTT1, broccoli, and prevalence of colorectal adenomas.
Pharmacogenetics 12: 175-9 (2002)
PM ID: 11875371
152: Brabender J, Lord RV, Wickramasinghe K, Metzger R, Schneider PM, Park JM, Hölscher AH, DeMeester TR, Danenberg KD, Danenberg PV
Glutathione S-transferase-pi expression is downregulated in patients with Barrett's esophagus and esophageal adenocarcinoma.
J Gastrointest Surg 6: 359-67 (2002)
PM ID: 12022988
153: Pais GC, Zhang XK, Marchand C, Neamati N, Cowansage K, Svarovskaia ES, Pathak VK, Tang Y, Nicklaus MC, Pommier Y, Burke TR
Structure activity of 3-aryl-1,3-diketo-containing compounds as HIV-1 integrase inhibitors.
J Med Chem 45: 3184-94 (2002)
PM ID: 12109903
154: Kim KM, Shibata D
Methylation reveals a niche: stem cell succession in human colon crypts.
Oncogene 21: 5441-9 (2002)
PM ID: 12154406
155: Tjuvajev JG, Doubrovin M, Akhurst T, Cai S, Balatoni J, Alauddin MM, Finn RS, Bornmann W, Thaler H, Conti PS, Blasberg RG
Comparison of radiolabeled nucleoside probes (FIAU, FHBG, and FHPG) for PET imaging of HSV1-tk gene expression.
J Nucl Med 43: 1072-83 (2002)
PM ID: 12163634
156: Swerdlow AJ, De Stavola BL, Floderus B, Holm NV, Kaprio J, Verkasalo PK, Mack TM
Risk factors for breast cancer at young ages in twins: an international population-based study.
J Natl Cancer Inst 94: 1238-46 (2002)
PM ID: 12189227
157: Virmani AK, Tsou JA, Siegmund KD, Shen LY, Long TI, Laird PW, Gazdar AF, Laird-Offringa IA
Hierarchical clustering of lung cancer cell lines using DNA methylation markers.
Cancer Epidemiol Biomarkers Prev 11: 291-7 (2002)
PM ID: 11895880
158: Grem JL, Danenberg KD, Kao V, Danenberg PV, Nguyen D
Biochemical and molecular effects of UCN-01 in combination with 5-fluorodeoxyuridine in A431 human epidermoid cancer cells.
Anticancer Drugs 13: 259-70 (2002)
PM ID: 11984070
159: Terry MB, Neugut AI, Bostick RM, Sandler RS, Haile RW, Jacobson JS, Fenoglio-Preiser CM, Potter JD
Risk factors for advanced colorectal adenomas: a pooled analysis.
Cancer Epidemiol Biomarkers Prev 11: 622-9 (2002)
PM ID: 12101109
160: Terry MB, Neugut AI, Bostick RM, Potter JD, Haile RW, Fenoglio-Preiser CM
Reliability in the classification of advanced colorectal adenomas.
Cancer Epidemiol Biomarkers Prev 11: 660-3 (2002)
PM ID: 12101114
161: Mack TM, Hamilton AS, Press MF, Diep AT, Rappaport EB
Heritable breast cancer in twins.
Br J Cancer 87: 294-300 (2002)
PM ID: 12177798 PMC2364223
162: She H, Xiong S, Lin MW, Zandi E, Giulivi C, Tsukamoto H
Iron activates NF-kappaB in Kupffer cells.
Am J Physiol Gastrointest Liver Physiol 283: G719-26 (2002)
PM ID: 12181188
163: Wu AH, Wan P, Hankin JH, Tseng CC, Yu MC, Pike MC
Adolescent and adult soy intake and risk of breast cancer in Asian-Americans.
Carcinogenesis 23: 1491-6 (2002)
PM ID: 12189192
164: Yen Y, Chow WA, Leong LA, Margolin K, Morgan RJ, Raschko J, Shibata SI, Somlo G, Twardowski P, Frankel P, Longmate J, Synold TW, Newman EM, Lenz HJ, Gandara D, Doroshow JH
Phase I pharmacodynamic study of time and sequence dependency of hydroxyurea in combination with gemcitabine: a California Cancer Consortium Trial.
Cancer Chemother Pharmacol 50: 353-9 (2002)
PM ID: 12439592
165: Jadvar H, Conti PS
Diagnostic utility of FDG PET in multiple myeloma.
Skeletal Radiol 31: 690-4 (2002)
PM ID: 12483429
166: Salonga DS, Danenberg KD, Grem JL, Park JM, Danenberg PV
Relative gene expression in normal and tumor tissue by quantitative RT-PCR.
Methods Mol Biol 191: 83-98 (2002)
PM ID: 11951611
167: Eads CA, Laird PW
Combined bisulfite restriction analysis (COBRA).
Methods Mol Biol 200: 71-85 (2002)
PM ID: 11951656
168: Lu W, Ou JH
Phosphorylation of hepatitis C virus core protein by protein kinase A and protein kinase C.
Virology 300: 20-30 (2002)
PM ID: 12202202
169: Tatlidil R, Jadvar H, Bading JR, Conti PS
Incidental colonic fluorodeoxyglucose uptake: correlation with colonoscopic and histopathologic findings.
Radiology 224: 783-7 (2002)
PM ID: 12202714
170: Tinkelenberg BA, Hansbury MJ, Ladner RD
dUTPase and uracil-DNA glycosylase are central modulators of antifolate toxicity in Saccharomyces cerevisiae.
Cancer Res 62: 4909-15 (2002)
PM ID: 12208740
171: Nakayama K, Kanzaki A, Ogawa K, Miyazaki K, Neamati N, Takebayashi Y
Copper-transporting P-type adenosine triphosphatase (ATP7B) as a cisplatin based chemoresistance marker in ovarian carcinoma: comparative analysis with expression of MDR1, MRP1, MRP2, LRP and BCRP.
Int J Cancer 101: 488-95 (2002)
PM ID: 12216079
172: Ehrlich M, Jiang G, Fiala E, Dome JS, Yu MC, Long TI, Youn B, Sohn OS, Widschwendter M, Tomlinson GE, Chintagumpala M, Champagne M, Parham D, Liang G, Malik K, Laird PW
Hypomethylation and hypermethylation of DNA in Wilms tumors.
Oncogene 21: 6694-702 (2002)
PM ID: 12242669
173: Goodman MT, Wu AH, Tung KH, McDuffie K, Cramer DW, Wilkens LR, Terada K, Reichardt JK, Ng WG
Association of galactose-1-phosphate uridyltransferase activity and N314D genotype with the risk of ovarian cancer.
Am J Epidemiol 156: 693-701 (2002)
PM ID: 12370157
174: Park DJ, Stoehlmacher J, Zhang W, Tsao-Wei DD, Groshen S, Lenz HJ
Thymidylate synthase gene polymorphism predicts response to capecitabine in advanced colorectal cancer.
Int J Colorectal Dis 17: 46-9 (2002)
PM ID: 12018454
175: Pullarkat V, Ngo M, Iqbal S, Espina BM, Liebman HA
Detection of lupus anticoagulant identifies patients with autoimmune haemolytic anaemia at increased risk for venous thromboembolism.
Br J Haematol 118: 1166-9 (2002)
PM ID: 12199802
176: Ladner RD
The role of dUTPase and uracil-DNA repair in cancer chemotherapy.
Curr Protein Pept Sci 2: 361-70 (2002)
PM ID: 12374095
177: Levine AJ, Elkhouly E, Diep AT, Lee ER, Frankl H, Haile RW
The MnSOD A16V mitochondrial targeting sequence polymorphism is not associated with increased risk of distal colorectal adenomas: data from a sigmoidoscopy-based case control study.
Cancer Epidemiol Biomarkers Prev 11: 1140-1 (2002)
PM ID: 12376525
178: Tsao JL, Dudley S, Kwok B, Nickel AE, Laird PW, Siegmund KD, Liskay RM, Shibata D
Diet, cancer and aging in DNA mismatch repair deficient mice.
Carcinogenesis 23: 1807-10 (2002)
PM ID: 12419828
179: Chen IJ, Neamati N, MacKerell AD
Structure-based inhibitor design targeting HIV-1 integrase.
Curr Drug Targets Infect Disord 2: 217-34 (2002)
PM ID: 12462126
180: Mack TM
A different view of smallpox and vaccination.
N Engl J Med 348: 460-3 (2002)
PM ID: 12496354
181: Lord RV, Brabender J, Gandara D, Alberola V, Camps C, Domine M, Cardenal F, Sánchez JM, Gumerlock PH, Tarón M, Sánchez JJ, Danenberg KD, Danenberg PV, Rosell R
Low ERCC1 expression correlates with prolonged survival after cisplatin plus gemcitabine chemotherapy in non-small cell lung cancer.
Clin Cancer Res 8: 2286-91 (2003)
PM ID: 12114432
182: Gong G, Oakley-Girvan I, Wu AH, Kolonel LN, John EM, West DW, Felberg A, Gallagher RP, Whittemore AS
Segregation analysis of prostate cancer in 1,719 white, African-American and Asian-American families in the United States and Canada.
Cancer Causes Control 13: 471-82 (2003)
PM ID: 12146852
183: Hamajima N, Hirose K, Tajima K, Rohan T, Calle EE, Heath CW, Coates RJ, Liff JM, Talamini R, Chantarakul N, Koetsawang S, Rachawat D, Morabia A, Schuman L, Stewart W, Szklo M, Bain C, Schofield F, Siskind V, Band P, Coldman AJ, Gallagher RP, Hislop TG, Yang PC, Kolonel LM, Nomura AM, Hu J, Johnson KC, Mao Y, De Sanjosé S, Lee NC, Marchbanks PA, Ory HW, Peterson HB, Wilson HG, Wingo PA, Ebeling K, Kunde D, Nishan P, Hopper JL, Colditz G, Gajalanski V, Martin N, Pardthaisong T, Silpisornkosol S, Theetranont C, Boosiri B, Chutivongse S, Jimakorn P, Virutamasen P, Wongsrichanalai C, Ewertz M, Adami HO, Bergkvist L, Magnusson C, Persson I, Chang-Claude J, Paul C, Skegg DC, Spears GF, Boyle P, Evstifeeva T, Daling JR, Hutchinson WB, Malone KE, Noonan EA, Stanford JL, Thomas DB, Weiss NS, White E, Andrieu N, Brêmond A, Clavel F, Gairard B, Lansac J, Piana L, Renaud R, Izquierdo A, Viladiu P, Cuevas HR, Ontiveros P, Palet A, Salazar SB, Aristizabel N, Cuadros A, Tryggvadottir L, Tulinius H, Bachelot A, Lê MG, Peto J, Franceschi S, Lubin F, Modan B, Ron E, Wax Y, Friedman GD, Hiatt RA, Levi F, Bishop T, Kosmelj K, Primic-Zakelj M, Ravnihar B, Stare J, Beeson WL, Fraser G, Bullbrook RD, Cuzick J, Duffy SW, Fentiman IS, Hayward JL, Wang DY, McMichael AJ, McPherson K, Hanson RL, Leske MC, Mahoney MC, Nasca PC, Varma AO, Weinstein AL, Moller TR, Olsson H, Ranstam J, Goldbohm RA, van den Brandt PA, Apelo RA, Baens J, de la Cruz JR, Javier B, Lacaya LB, Ngelangel CA, La Vecchia C, Negri E, Marubini E, Ferraroni M, Gerber M, Richardson S, Segala C, Gatei D, Kenya P, Kungu A, Mati JG, Brinton LA, Hoover R, Schairer C, Spirtas R, Lee HP, Rookus MA, van Leeuwen FE, Schoenberg JA, McCredie M, Gammon MD, Clarke EA, Jones LA, Neil A, Vessey M, Yeates D, Appleby P, Banks E, Beral V, Bull D, Crossley B, Goodill A, Green J, Hermon C, Key T, Langston N, Lewis C, Reeves G, Collins R, Doll R, Peto R, Mabuchi K, Preston D, Hannaford P, Kay C, Rosero-Bixby L, Gao YT, Jin F, Yuan JM, Wei HY, Yun T, Zhiheng C, Berry G, Cooper Booth J, Jelihovsky T, MacLennan R, Shearman R, Wang QS, Baines CJ, Miller AB, Wall C, Lund E, Stalsberg H, Shu XO, Zheng W, Katsouyanni K, Trichopoulou A, Trichopoulos D, Dabancens A, Martinez L, Molina R, Salas O, Alexander FE, Anderson K, Folsom AR, Hulka BS, Bernstein L, Enger SM, Haile RW, Paganini-Hill A, Pike MC, Ross RK, Ursin G, Yu MC, Longnecker MP, Newcomb P, Bergkvist L, Kalache A, Farley TM, Holck S, Meirik O, Collaborative Group on Hormonal Factors in Breast
Alcohol, tobacco and breast cancer--collaborative reanalysis of individual data from 53 epidemiological studies, including 58,515 women with breast cancer and 95,067 women without the disease.
Br J Cancer 87: 1234-45 (2003)
PM ID: 12439712 PMC2562507
184: Neamati N, Lin Z, Karki RG, Orr A, Cowansage K, Strumberg D, Pais GC, Voigt JH, Nicklaus MC, Winslow HE, Zhao H, Turpin JA, Yi J, Skalka AM, Burke TR, Pommier Y
Metal-dependent inhibition of HIV-1 integrase.
J Med Chem 45: 5661-70 (2003)
PM ID: 12477350
185: Xu Z, Choi J, Lu W, Ou JH
Hepatitis C virus f protein is a short-lived protein associated with the endoplasmic reticulum.
J Virol 77: 1578-83 (2003)
PM ID: 12502871 PMC140853
186: Lin WJ, Li JZ, Lee YF, Yeh SD, Altuwaijri S, Ou JH, Chang CC
Suppression of hepatitis B virus core promoter by the nuclear orphan receptor TR4.
J Biol Chem 278: 9353-60 (2003)
PM ID: 12522137
187: Kaplowitz N, Lewis JH, Watkins PB
Did this drug cause my patient's hepatitis?
Ann Intern Med 138: 159-60; author reply 159-60 (2003)
PM ID: 12529106
188: Tsukamoto H
Iron regulation of hepatic macrophage TNFalpha expression.
Free Radic Biol Med 32: 309-13 (2003)
PM ID: 11841920
189: Neamati N, Barchi JJ
New paradigms in drug design and discovery.
Curr Top Med Chem 2: 211-27 (2003)
PM ID: 11944817
190: Lu SC, Tsukamoto H, Mato JM
Role of abnormal methionine metabolism in alcoholic liver injury.
Alcohol 27: 155-62 (2003)
PM ID: 12163143
191: Bernstein JL, Thompson WD, Casey GR, DiCioccio RA, Whittemore AS, Diep AT, Thakore SS, Vaziri S, Xue S, Haile RW
Comparison of techniques for the successful detection of BRCA1 mutations in fixed paraffin-embedded tissue.
Cancer Epidemiol Biomarkers Prev 11: 809-14 (2003)
PM ID: 12223423
192: Wu AH, Stanczyk FZ, Seow A, Lee HP, Yu MC
Soy intake and other lifestyle determinants of serum estrogen levels among postmenopausal Chinese women in Singapore.
Cancer Epidemiol Biomarkers Prev 11: 844-51 (2003)
PM ID: 12223428
193: Ringold DA, Nicoloff JT, Kesler M, Davis H, Hamilton A, Mack TM
Further evidence for a strong genetic influence on the development of autoimmune thyroid disease: the California twin study.
Thyroid 12: 647-53 (2003)
PM ID: 12225632
194: Pluymers W, Pais GC, Van Maele B, Pannecouque C, Fikkert V, Burke TR, De Clercq E, Witvrouw M, Neamati N, Debyser Z
Inhibition of human immunodeficiency virus type 1 integration by diketo derivatives.
Antimicrob Agents Chemother 46: 3292-7 (2003)
PM ID: 12234864 PMC128766
195: Liu ZX, Kaplowitz N
Immune-mediated drug-induced liver disease.
Clin Liver Dis 6: 755-74 (2003)
PM ID: 12362579
196: Wu AH, Crabtree JE, Bernstein L, Hawtin P, Cockburn MG, Tseng CC, Forman D
Role of Helicobacter pylori CagA+ strains and risk of adenocarcinoma of the stomach and esophagus.
Int J Cancer 103: 815-21 (2003)
PM ID: 12516104
197: Aparicio AM, Eads CA, Leong LA, Laird PW, Newman EM, Synold TW, Baker SD, Zhao M, Weber JS
Phase I trial of continuous infusion 5-aza-2'-deoxycytidine.
Cancer Chemother Pharmacol 51: 231-9 (2003)
PM ID: 12655442
198: Lenz HJ, Anderson WF, Hall FL, Gordon EM
Clinical protocol. Tumor site specific phase I evaluation of safety and efficacy of hepatic arterial infusion of a matrix-targeted retroviral vector bearing a dominant negative cyclin G1 construct as intervention for colorectal carcinoma metastatic to liver.
Hum Gene Ther 13: 1515-37 (2003)
PM ID: 12215272
199: Lin HJ, Lakkides KM, Keku TO, Reddy ST, Louie AD, Kau IH, Zhou H, Gim JS, Ma HL, Matthies CF, Dai A, Huang HF, Materi AM, Lin JH, Frankl HD, Lee ER, Hardy SI, Herschman HR, Henderson BE, Kolonel LN, Le Marchand L, Garavito RM, Sandler RS, Haile RW, Smith WL
Prostaglandin H synthase 2 variant (Val511Ala) in African Americans may reduce the risk for colorectal neoplasia.
Cancer Epidemiol Biomarkers Prev 11: 1305-15 (2003)
PM ID: 12433707
200: Karanjawala ZE, Adachi N, Irvine RA, Oh EK, Shibata D, Schwarz K, Hsieh CL, Lieber MR
The embryonic lethality in DNA ligase IV-deficient mice is rescued by deletion of Ku: implications for unifying the heterogeneous phenotypes of NHEJ mutants.
DNA Repair (Amst) 1: 1017-26 (2003)
PM ID: 12531011
201: Cockburn MG, Hamilton A, Zadnick J, Cozen W, Mack TM
The occurrence of chronic disease and other conditions in a large population-based cohort of native Californian twins.
Twin Res 5: 460-7 (2003)
PM ID: 12537877
202: Elateri I, Tinkelenberg BA, Hansbury M, Caradonna SJ, Muller-Weeks S, Ladner RD
hSMUG1 can functionally compensate for Ung1 in the yeast Saccharomyces cerevisiae.
DNA Repair (Amst) 2: 315-23 (2003)
PM ID: 12547394
203: Lord RV, Park JM, Wickramasinghe K, DeMeester SR, Oberg S, Salonga D, Singer JB, Peters JH, Danenberg KD, DeMeester TR, Danenberg PV
Vascular endothelial growth factor and basic fibroblast growth factor expression in esophageal adenocarcinoma and Barrett esophagus.
J Thorac Cardiovasc Surg 125: 246-53 (2003)
PM ID: 12579092
204: Formenti SC, Volm M, Skinner KA, Spicer D, Cohen D, Perez E, Bettini AC, Groshen S, Gee C, Florentine B, Press MF, Danenberg P, Muggia FM
Preoperative twice-weekly paclitaxel with concurrent radiation therapy followed by surgery and postoperative doxorubicin-based chemotherapy in locally advanced breast cancer: a phase I/II trial.
J Clin Oncol 21: 864-70 (2003)
PM ID: 12610186
205: Lluis JM, Colell A, García-Ruiz C, Kaplowitz N, Fernández-Checa JC
Acetaldehyde impairs mitochondrial glutathione transport in HepG2 cells through endoplasmic reticulum stress.
Gastroenterology 124: 708-24 (2003)
PM ID: 12612910
206: Baron JA, Cole BF, Sandler RS, Haile RW, Ahnen DJ, Bresalier RS, McKeown-Eyssen GE, Summers RW, Rothstein RI, Burke CA, Snover DC, Church TR, Allen JI, Beach M, Beck GJ, Bond JH, Byers T, Greenberg ER, Mandel JS, Marcon N, Mott LA, Pearson LH, Saibil F, Van Stolk RU
A randomized trial of aspirin to prevent colorectal adenomas.
N Engl J Med 348: 891-9 (2003)
PM ID: 12621133
207: Xiong S, She H, Takeuchi H, Han B, Engelhardt JF, Barton CH, Zandi E, Giulivi C, Tsukamoto H
Signaling role of intracellular iron in NF-kappaB activation.
J Biol Chem 278: 17646-54 (2003)
PM ID: 12637578
208: Neuman MG, Katz GG, Malkiewicz IM, Mathurin P, Tsukamoto H, Adachi M, Ishii H, Colell A, García-Ruiz C, Fernández-Checa JC, Casey CA
Alcoholic liver injury and apoptosis--synopsis of the symposium held at ESBRA 2001: 8th Congress of the European Society for Biomedical Research on Alcoholism, Paris, September 16, 2001.
Alcohol 28: 117-28 (2003)
PM ID: 12457943
209: Tsukamoto H
Redox regulation of cytokine expression in Kupffer cells.
Antioxid Redox Signal 4: 741-8 (2003)
PM ID: 12470501
210: Neamati N
Dipyrimidine-based inhibitors of HIV-1 integrase.
Expert Opin Investig Drugs 12: 289-92 (2003)
PM ID: 12556222
211: Tsien F, Fiala ES, Youn B, Long TI, Laird PW, Weissbecker K, Ehrlich M
Prolonged culture of normal chorionic villus cells yields ICF syndrome-like chromatin decondensation and rearrangements.
Cytogenet Genome Res 98: 13-21 (2003)
PM ID: 12584436
212: Wu AH, Seow A, Arakawa K, Van Den Berg D, Lee HP, Yu MC
HSD17B1 and CYP17 polymorphisms and breast cancer risk among Chinese women in Singapore.
Int J Cancer 104: 450-7 (2003)
PM ID: 12584742
213: Choi J, Xu Z, Ou JH
Triple decoding of hepatitis C virus RNA by programmed translational frameshifting.
Mol Cell Biol 23: 1489-97 (2003)
PM ID: 12588970 PMC151691
214: Jadvar H, Tatlidil R, Garcia AA, Conti PS
Evaluation of recurrent gastric malignancy with [F-18]-FDG positron emission tomography.
Clin Radiol 58: 215-21 (2003)
PM ID: 12639527
215: Bernstein JL, Teraoka S, Haile RW, Børresen-Dale AL, Rosenstein BS, Gatti RA, Diep AT, Jansen L, Atencio DP, Olsen JH, Bernstein L, Teitelbaum SL, Thompson WD, Concannon P
Designing and implementing quality control for multi-center screening of mutations in the ATM gene among women with breast cancer.
Hum Mutat 21: 542-50 (2003)
PM ID: 12673797
216: Sussman S, Dent CW, Skara S, de Calice P, Tsukamoto H
Alcoholic liver disease (ALD): a new domain for prevention efforts.
Subst Use Misuse 37: 1887-904 (2003)
PM ID: 12511057
217: Laird PW
The power and the promise of DNA methylation markers.
Nat Rev Cancer 3: 253-66 (2003)
PM ID: 12671664
218: Iqbal S, Lenz HJ
Targeted therapy and pharmacogenomic programs.
Cancer 97: 2076-82 (2003)
PM ID: 12673699
219: Cottrell SE, Laird PW
Sensitive detection of DNA methylation.
Ann N Y Acad Sci 983: 120-30 (2003)
PM ID: 12724217
220: Ji C, Kaplowitz N
Betaine decreases hyperhomocysteinemia, endoplasmic reticulum stress, and liver injury in alcohol-fed mice.
Gastroenterology 124: 1488-99 (2003)
PM ID: 12730887
221: Yang D, Bernstein L, Wu AH
Physical activity and breast cancer risk among Asian-American women in Los Angeles: a case-control study.
Cancer 97: 2565-75 (2003)
PM ID: 12733156
222: Shibata D
Molecular tumour clocks and colorectal cancer: seeing the unseen.
Pathology 34: 534-40 (2003)
PM ID: 12555991
223: Neamati N, Murthy M, Wang YX
Preparation of DNA-protein complexes suitable for spectroscopic analysis.
Methods Mol Med 85: 185-202 (2003)
PM ID: 12710209
224: Lenz HJ
Clinical update: proteasome inhibitors in solid tumors.
Cancer Treat Rev 29 Suppl 1: 41-8 (2003)
PM ID: 12738242
225: Baron JA, Cole BF, Mott L, Haile R, Grau M, Church TR, Beck GJ, Greenberg ER
Neoplastic and antineoplastic effects of beta-carotene on colorectal adenoma recurrence: results of a randomized trial.
J Natl Cancer Inst 95: 717-22 (2003)
PM ID: 12759389
226: Stram DO, Wu AH
Re: Beta-carotene and lung cancer: a lesson for future chemoprevention investigations?
J Natl Cancer Inst 95: E4 (2003)
PM ID: 12759404
227: Matsumaru K, Ji C, Kaplowitz N
Mechanisms for sensitization to TNF-induced apoptosis by acute glutathione depletion in murine hepatocytes.
Hepatology 37: 1425-34 (2003)
PM ID: 12774022
228: Hamilton AS, Mack TM
Puberty and genetic susceptibility to breast cancer in a case-control study in twins.
N Engl J Med 348: 2313-22 (2003)
PM ID: 12788995
229: Brabender J, Usadel H, Metzger R, Schneider PM, Park JM, Salonga D, Tsao-Wei DD, Groshen S, Lord RV, Takebe N, Schneider S, Hölscher AH, Danenberg KD, Danenberg PV
Quantitative O(6)-methylguanine DNA methyltransferase methylation analysis in curatively resected non-small cell lung cancer: associations with clinical outcome.
Clin Cancer Res 9: 223-7 (2003)
PM ID: 12538473
230: Mandola MV, Stoehlmacher J, Muller-Weeks S, Cesarone G, Yu MC, Lenz HJ, Ladner RD
A novel single nucleotide polymorphism within the 5' tandem repeat polymorphism of the thymidylate synthase gene abolishes USF-1 binding and alters transcriptional activity.
Cancer Res 63: 2898-904 (2003)
PM ID: 12782596
231: Uhlmann K, Rohde K, Zeller C, Szymas J, Vogel S, Marczinek K, Thiel G, Nürnberg P, Laird PW
Distinct methylation profiles of glioma subtypes.
Int J Cancer 106: 52-9 (2003)
PM ID: 12794756
232: Tinkelenberg BA, Fazzone W, Lynch FJ, Ladner RD
Identification of sequence determinants of human nuclear dUTPase isoform localization.
Exp Cell Res 287: 39-46 (2003)
PM ID: 12799180
233: Stoehlmacher J, Lenz HJ
Cyclooxygenase-2 inhibitors in colorectal cancer.
Semin Oncol 30: 10-6 (2003)
PM ID: 12802790
234: Lou H, Ookhtens M, Stolz A, Kaplowitz N
Chelerythrine stimulates GSH transport by rat Mrp2 (Abcc2) expressed in canine kidney cells.
Am J Physiol Gastrointest Liver Physiol 285: G1335-44 (2003)
PM ID: 12893631
235: Siegmund KD, Laird PW
Analysis of complex methylation data.
Methods 27: 170-8 (2003)
PM ID: 12095277
236: Kawakami K, Ishida Y, Danenberg KD, Omura K, Watanabe G, Danenberg PV
Functional polymorphism of the thymidylate synthase gene in colorectal cancer accompanied by frequent loss of heterozygosity.
Jpn J Cancer Res 93: 1221-9 (2003)
PM ID: 12460463
237: Farrugia DC, Ford HE, Cunningham D, Danenberg KD, Danenberg PV, Brabender J, McVicar AD, Aherne GW, Hardcastle A, McCarthy K, Jackman AL
Thymidylate synthase expression in advanced colorectal cancer predicts for response to raltitrexed.
Clin Cancer Res 9: 792-801 (2003)
PM ID: 12576452
238: Stoehlmacher J, Lenz HJ
Implications of genetic testing in the management of colorectal cancer.
Am J Pharmacogenomics 3: 73-88 (2003)
PM ID: 12749725
239: Zheng YT, Li JZ, Johnson DL, Ou JH
Regulation of hepatitis B virus replication by the ras-mitogen-activated protein kinase signaling pathway.
J Virol 77: 7707-12 (2003)
PM ID: 12829809 PMC161924
240: Bading JR, Yoo PB, Fissekis JD, Alauddin MM, D'Argenio DZ, Conti PS
Kinetic modeling of 5-fluorouracil anabolism in colorectal adenocarcinoma: a positron emission tomography study in rats.
Cancer Res 63: 3667-74 (2003)
PM ID: 12839957
241: Einspahr JG, Krouse RS, Yochim JM, Danenberg PV, Danenberg KD, Bhattacharyya AK, Martínez ME, Alberts DS
Association between Cyclooxygenase expression and colorectal adenoma characteristics.
Cancer Res 63: 3891-3 (2003)
PM ID: 12873979
242: Ursin G, Ma H, Wu AH, Bernstein L, Salane M, Parisky YR, Astrahan M, Siozon CC, Pike MC
Mammographic density and breast cancer in three ethnic groups.
Cancer Epidemiol Biomarkers Prev 12: 332-8 (2003)
PM ID: 12692108
243: Alauddin MM, Louie AY, Shahinian A, Meade TJ, Conti PS
Receptor mediated uptake of a radiolabeled contrast agent sensitive to beta-galactosidase activity.
Nucl Med Biol 30: 261-5 (2003)
PM ID: 12745017
244: Wu AH, Yu MC, Tseng CC, Hankin JH, Pike MC
Green tea and risk of breast cancer in Asian Americans.
Int J Cancer 106: 574-9 (2003)
PM ID: 12845655
245: Ramanathan RK, Clark JW, Kemeny NE, Lenz HJ, Gococo KO, Haller DG, Mitchell EP, Kardinal CG
Safety and toxicity analysis of oxaliplatin combined with fluorouracil or as a single agent in patients with previously treated advanced colorectal cancer.
J Clin Oncol 21: 2904-11 (2003)
PM ID: 12885808
246: Wu AH, Tseng CC, Bernstein L
Hiatal hernia, reflux symptoms, body size, and risk of esophageal and gastric adenocarcinoma.
Cancer 98: 940-8 (2003)
PM ID: 12942560
247: Alauddin MM, Shahinian A, Gordon EM, Conti PS
Evaluation of 2'-deoxy-2'-flouro-5-methyl-1-beta-D-arabinofuranosyluracil as a potential gene imaging agent for HSV-tk expression in vivo.
Mol Imaging 1: 74-81 (2003)
PM ID: 12920847
248: Coll O, Colell A, García-Ruiz C, Kaplowitz N, Fernández-Checa JC
Sensitivity of the 2-oxoglutarate carrier to alcohol intake contributes to mitochondrial glutathione depletion.
Hepatology 38: 692-702 (2003)
PM ID: 12939596
249: Tung KH, Goodman MT, Wu AH, McDuffie K, Wilkens LR, Kolonel LN, Nomura AM, Terada KY, Carney ME, Sobin LH
Reproductive factors and epithelial ovarian cancer risk by histologic type: a multiethnic case-control study.
Am J Epidemiol 158: 629-38 (2003)
PM ID: 14507598
250: Wu AH, Yu MC, Tseng CC, Twaddle NC, Doerge DR
Plasma isoflavone levels versus self-reported soy isoflavone levels in Asian-American women in Los Angeles County.
Carcinogenesis 25: 77-81 (2003)
PM ID: 14555615
251: Zhang AS, Xiong S, Tsukamoto H, Enns CA
Localization of iron metabolism-related mRNAs in rat liver indicate that HFE is expressed predominantly in hepatocytes.
Blood 103: 1509-14 (2003)
PM ID: 14563638
252: Doroshow JH, Synold TW, Gandara D, Mani S, Remick SC, Mulkerin DL, Hamilton A, Sharma S, Ramanathan RK, Lenz HJ, Graham MM, Longmate J, Takimoto CH, Ivy P
Pharmacology of oxaliplatin in solid tumor patients with hepatic dysfunction: a preliminary report of the National Cancer Institute Organ Dysfunction Working Group.
Semin Oncol 30: 14-9 (2003)
PM ID: 14523790
253: Lenz HJ
Pharmacogenomics in colorectal cancer.
Semin Oncol 30: 47-53 (2003)
PM ID: 14523795
254: Oakley-Girvan I, Kolonel LN, Gallagher RP, Wu AH, Felberg A, Whittemore AS
Stage at diagnosis and survival in a multiethnic cohort of prostate cancer patients.
Am J Public Health 93: 1753-9 (2003)
PM ID: 14534233 PMC1448045
255: Brabender J, Lord RV, Metzger R, Park JM, Salonga D, Danenberg KD, Danenberg PV, Hölscher AH, Schneider PM
Differential SPARC mRNA expression in Barrett's oesophagus.
Br J Cancer 89: 1508-12 (2003)
PM ID: 14562024 PMC2394336
256: Bernstein JL, Bernstein L, Thompson WD, Lynch CF, Malone KE, Teitelbaum SL, Olsen JH, Anton-Culver H, Boice JD, Rosenstein BS, Børresen-Dale AL, Gatti RA, Concannon P, Haile RW, WECARE Study Collaborative Group
ATM variants 7271T>G and IVS10-6T>G among women with unilateral and bilateral breast cancer.
Br J Cancer 89: 1513-6 (2003)
PM ID: 14562025 PMC2394328
257: Han D, Canali R, Rettori D, Kaplowitz N
Effect of glutathione depletion on sites and topology of superoxide and hydrogen peroxide production in mitochondria.
Mol Pharmacol 64: 1136-44 (2003)
PM ID: 14573763
258: Han YP, Zhou L, Wang JG, Xiong S, Garner WL, French SW, Tsukamoto H
Essential role of matrix metalloproteinases in interleukin-1-induced myofibroblastic activation of hepatic stellate cell in collagen.
J Biol Chem 279: 4820-8 (2003)
PM ID: 14617627 PMC2430939 NIHMS46531
259: Patel AV, Callel EE, Bernstein L, Wu AH, Thun MJ
Recreational physical activity and risk of postmenopausal breast cancer in a large cohort of US women.
Cancer Causes Control 14: 519-29 (2003)
PM ID: 12948283
260: Sung CK, She H, Xiong S, Tsukamoto H
Tumor necrosis factor-alpha inhibits peroxisome proliferator-activated receptor gamma activity at a posttranslational level in hepatic stellate cells.
Am J Physiol Gastrointest Liver Physiol 286: G722-9 (2003)
PM ID: 14656714
261: Hazra S, Xiong S, Wang JG, Rippe RA, Krishna V, Chatterjee K, Tsukamoto H
Peroxisome proliferator-activated receptor gamma induces a phenotypic switch from activated to quiescent hepatic stellate cells.
J Biol Chem 279: 11392-401 (2003)
PM ID: 14702344
262: Cozen W, Gill PS, Ingles SA, Masood R, Martínez-Maza O, Cockburn MG, Gauderman WJ, Pike MC, Bernstein L, Nathwani BN, Salam MT, Danley KL, Wang W, Gage J, Gundell-Miller S, Mack TM
IL-6 levels and genotype are associated with risk of young adult Hodgkin lymphoma.
Blood 103: 3216-21 (2003)
PM ID: 15070705
263: Park DJ, Stoehlmacher J, Lenz HJ
Tailoring chemotherapy in advanced colorectal cancer.
Curr Opin Pharmacol 3: 378-85 (2004)
PM ID: 12901946
264: Francis GS, Grumser Y, Alteri E, Micaleff A, O'Brien F, Alsop J, Stam Moraga M, Kaplowitz N
Hepatic reactions during treatment of multiple sclerosis with interferon-beta-1a: incidence and clinical significance.
Drug Saf 26: 815-27 (2004)
PM ID: 12908850
265: Wu AH, Tseng CC, Van Den Berg D, Yu MC
Tea intake, COMT genotype, and breast cancer in Asian-American women.
Cancer Res 63: 7526-9 (2004)
PM ID: 14612555
266: Grau MV, Baron JA, Sandler RS, Haile RW, Beach ML, Church TR, Heber D
Vitamin D, calcium supplementation, and colorectal adenomas: results of a randomized trial.
J Natl Cancer Inst 95: 1765-71 (2004)
PM ID: 14652238
267: Pagliarulo V, George B, Beil SJ, Groshen S, Laird PW, Cai J, Willey J, Cote RJ, Datar RH
Sensitivity and reproducibility of standardized-competitive RT-PCR for transcript quantification and its comparison with real time RT-PCR.
Mol Cancer 3: 5 (2004)
PM ID: 14741054 PMC344741
268: Iqbal S, Lenz HJ
Molecular predictors of treatment and outcome in colorectal cancer.
Curr Gastroenterol Rep 5: 399-405 (2004)
PM ID: 12959721
269: Hecht JR, Blanke CD, Benson AB, Lenz HJ
Irinotecan and paclitaxel in metastatic adenocarcinoma of the esophagus and gastric cardia.
Oncology (Williston Park) 17: 13-5 (2004)
PM ID: 14569841
270: Stoehlmacher J, Goekkurt E, Lenz HJ
Pharmacogenetic aspects in treatment of colorectal cancer--an update.
Pharmacogenomics 4: 767-77 (2004)
PM ID: 14596640
271: Half E, Broaddus R, Danenberg KD, Danenberg PV, Ayers GD, Sinicrope FA
HER-2 receptor expression, localization, and activation in colorectal cancer cell lines and human tumors.
Int J Cancer 108: 540-8 (2004)
PM ID: 14696118
272: Chen Z, Wu AH, Gauderman WJ, Bernstein L, Ma H, Pike MC, Ursin G
Does mammographic density reflect ethnic differences in breast cancer incidence rates?
Am J Epidemiol 159: 140-7 (2004)
PM ID: 14718215
273: Vineis P, Alavanja MC, Buffler P, Fontham ET, Franceschi S, Gao YT, Gupta PC, Hackshaw A, Matos E, Samet JM, Sitas F, Smith JR, Stayner L, Straif K, Thun MJ, Wichmann HE, Wu AH, Zaridze D, Peto R, Doll R
Tobacco and cancer: recent epidemiological evidence.
J Natl Cancer Inst 96: 99-106 (2004)
PM ID: 14734699
274: Kuo CL, Assefa H, Kamath S, Brzozowski Z, Slawinski J, Saczewski F, Buolamwini JK, Neamati N
Application of CoMFA and CoMSIA 3D-QSAR and docking studies in optimization of mercaptobenzenesulfonamides as HIV-1 integrase inhibitors.
J Med Chem 47: 385-99 (2004)
PM ID: 14711310
275: Chen X, Park R, Tohme M, Shahinian AH, Bading JR, Conti PS
MicroPET and autoradiographic imaging of breast cancer alpha v-integrin expression using 18F- and 64Cu-labeled RGD peptide.
Bioconjug Chem 15: 41-9 (2004)
PM ID: 14733582
276: Brennan P, Buffler PA, Reynolds P, Wu AH, Wichmann HE, Agudo A, Pershagen G, Jöckel KH, Benhamou S, Greenberg RS, Merletti F, Winck C, Fontham ET, Kreuzer M, Darby SC, Forastiere F, Simonato L, Boffetta P
Secondhand smoke exposure in adulthood and risk of lung cancer among never smokers: a pooled analysis of two large studies.
Int J Cancer 109: 125-31 (2004)
PM ID: 14735478
277: Choi J, Lee KJ, Zheng YT, Yamaga AK, Lai MM, Ou JH
Reactive oxygen species suppress hepatitis C virus RNA replication in human hepatoma cells.
Hepatology 39: 81-9 (2004)
PM ID: 14752826
278: Kaplowitz N
Drug-induced liver injury.
Clin Infect Dis 38 Suppl 2: S44-8 (2004)
PM ID: 14986274
279: Siegmund KD, Laird PW, Laird-Offringa IA
A comparison of cluster analysis methods using DNA methylation data.
Bioinformatics 20: 1896-904 (2004)
PM ID: 15044245
280: Bernstein JL, Langholz B, Haile RW, Bernstein L, Thomas DC, Stovall M, Malone KE, Lynch CF, Olsen JH, Anton-Culver H, Shore RE, Boice JD, Berkowitz GS, Gatti RA, Teitelbaum SL, Smith SA, Rosenstein BS, Børresen-Dale AL, Concannon P, Thompson WD, WECARE study
Study design: evaluating gene-environment interactions in the etiology of breast cancer - the WECARE study.
Breast Cancer Res 6: R199-214 (2004)
PM ID: 15084244 PMC400669
281: Kojima H, Kaita KD, Xu Z, Ou JH, Gong Y, Zhang M, Minuk GY
The absence of up-regulation of telomerase activity during regeneration after partial hepatectomy in hepatitis B virus X gene transgenic mice.
J Hepatol 39: 262-8 (2004)
PM ID: 12873824
282: Jadvar H, Pinski JK, Conti PS
FDG PET in suspected recurrent and metastatic prostate cancer.
Oncol Rep 10: 1485-8 (2004)
PM ID: 12883728
283: Xiong S, She H, Sung CK, Tsukamoto H
Iron-dependent activation of NF-kappaB in Kupffer cells: a priming mechanism for alcoholic liver disease.
Alcohol 30: 107-13 (2004)
PM ID: 12957294
284: Jadvar H, Kherbache HM, Pinski JK, Conti PS
Diagnostic role of [F-18]-FDG positron emission tomography in restaging renal cell carcinoma.
Clin Nephrol 60: 395-400 (2004)
PM ID: 14690256
285: Lee KJ, Choi J, Ou JH, Lai MM
The C-terminal transmembrane domain of hepatitis C virus (HCV) RNA polymerase is essential for HCV replication in vivo.
J Virol 78: 3797-802 (2004)
PM ID: 15016899 PMC371049
286: Han D, Matsumaru K, Rettori D, Kaplowitz N
Usnic acid-induced necrosis of cultured mouse hepatocytes: inhibition of mitochondrial function and oxidative stress.
Biochem Pharmacol 67: 439-51 (2004)
PM ID: 15037196
287: Calabrese P, Tavaré S, Shibata D
Pretumor progression: clonal evolution of human stem cell populations.
Am J Pathol 164: 1337-46 (2004)
PM ID: 15039221 PMC1615336
288: Kim KM, Calabrese P, Tavaré S, Shibata D
Enhanced stem cell survival in familial adenomatous polyposis.
Am J Pathol 164: 1369-77 (2004)
PM ID: 15039224 PMC1615334
289: Calabrese P, Tsao JL, Yatabe Y, Salovaara R, Mecklin JP, Järvinen HJ, Aaltonen LA, Tavaré S, Shibata D
Colorectal pretumor progression before and after loss of DNA mismatch repair.
Am J Pathol 164: 1447-53 (2004)
PM ID: 15039232 PMC1615342
290: Veal N, Hsieh CL, Xiong S, Mato JM, Lu SC, Tsukamoto H
Inhibition of lipopolysaccharide-stimulated TNF-alpha promoter activity by S-adenosylmethionine and 5'-methylthioadenosine.
Am J Physiol Gastrointest Liver Physiol 287: G352-62 (2004)
PM ID: 15064230
291: Chen X, Park R, Hou Y, Khankaldyyan V, Gonzales-Gomez I, Tohme M, Bading JR, Laug WE, Conti PS
MicroPET imaging of brain tumor angiogenesis with 18F-labeled PEGylated RGD peptide.
Eur J Nucl Med Mol Imaging 31: 1081-9 (2004)
PM ID: 15118844
292: Dayam R, Neamati N
Small-molecule HIV-1 integrase inhibitors: the 2001-2002 update.
Curr Pharm Des 9: 1789-802 (2004)
PM ID: 12871197
293: Schmittgen TD, Ju JF, Danenberg KD, Danenberg PV
Inhibition of pre-mRNA splicing by cisplatin and platinum analogs.
Int J Oncol 23: 785-9 (2004)
PM ID: 12888918
294: Juhasz A, Frankel P, Cheng CY, Rivera H, Vishwanath R, Chiu A, Margolin K, Yen Y, Newman EM, Synold TW, Wilczynski S, Lenz HJ, Gandara D, Albain KS, Longmate J, Doroshow JH
Quantification of chemotherapeutic target gene mRNA expression in human breast cancer biopsies: comparison of real-time reverse transcription-PCR vs. relative quantification reverse transcription-PCR utilizing DNA sequencer analysis of PCR products.
J Clin Lab Anal 17: 184-94 (2004)
PM ID: 12938148
295: Lara PN, Frankel P, Mack PC, Gumerlock PH, Galvin I, Martel CL, Longmate J, Doroshow JH, Lenz HJ, Lau DH, Gandara DR
Tirapazamine plus carboplatin and paclitaxel in advanced malignant solid tumors: a california cancer consortium phase I and molecular correlative study.
Clin Cancer Res 9: 4356-62 (2004)
PM ID: 14555506
296: Tseng HF, Morgenstern H, Mack TM, Peters RK
Risk factors for anal cancer: results of a population-based case--control study.
Cancer Causes Control 14: 837-46 (2004)
PM ID: 14682441
297: Conti PS
Radioimmunotherapy with yttrium 90 ibritumomab tiuxetan (Zevalin): the role of the nuclear medicine physician.
Semin Nucl Med 34: 2-3 (2004)
PM ID: 14762737
298: Hawkins SA, Cockburn MG, Hamilton AS, Mack TM
An estimate of physical activity prevalence in a large population-based cohort.
Med Sci Sports Exerc 36: 253-60 (2004)
PM ID: 14767248
299: Tung KH, Goodman MT, Wu AH, McDuffie K, Wilkens LR, Nomura AM, Kolonel LN
Aggregation of ovarian cancer with breast, ovarian, colorectal, and prostate cancer in first-degree relatives.
Am J Epidemiol 159: 750-8 (2004)
PM ID: 15051584
300: Lara PN, Quinn DI, Margolin K, Meyers FJ, Longmate J, Frankel P, Mack PC, Turrell C, Valk P, Rao JY, Buckley P, Wun T, Gosselin R, Galvin I, Gumerlock PH, Lenz HJ, Doroshow JH, Gandara DR, California Cancer Consortium
SU5416 plus interferon alpha in advanced renal cell carcinoma: a phase II California Cancer Consortium Study with biological and imaging correlates of angiogenesis inhibition.
Clin Cancer Res 9: 4772-81 (2004)
PM ID: 14581348
301: Tao N, Sussman S, Nieto J, Tsukamoto H, Yuan JM
Demographic characteristics of hospitalized patients with alcoholic liver disease and pancreatitis in los angeles county.
Alcohol Clin Exp Res 27: 1798-804 (2004)
PM ID: 14634496
302: Yu P, Neamati N, Tarasov S, He QY, Sheikh MS, Wang YX
Codon-optimized cloning, expression and characertization of the C-terminal region of human apoptotic protein GADD34 in Escherichia coli.
Cell Cycle 3: 75-9 (2004)
PM ID: 14657671
303: Li JZ, Zheng YT, Choi J, Ou JH
Phosphorylation analysis of hepatitis B virus core protein in mammalian cells.
Methods Mol Med 95: 227-33 (2004)
PM ID: 14762306
304: Xu Z, Ou JH
Endogenous polymerase assay for the analysis of hepatitis B virus in transgenic mice.
Methods Mol Med 95: 295-302 (2004)
PM ID: 14762312
305: Brabender J, Marjoram P, Salonga D, Metzger R, Schneider PM, Park JM, Schneider S, Hölscher AH, Yin J, Meltzer SJ, Danenberg KD, Danenberg PV, Lord RV
A multigene expression panel for the molecular diagnosis of Barrett's esophagus and Barrett's adenocarcinoma of the esophagus.
Oncogene 23: 4780-8 (2004)
PM ID: 15107828
306: Long YQ, Jiang XH, Dayam R, Sanchez TW, Shoemaker R, Sei S, Neamati N
Rational design and synthesis of novel dimeric diketoacid-containing inhibitors of HIV-1 integrase: implication for binding to two metal ions on the active site of integrase.
J Med Chem 47: 2561-73 (2004)
PM ID: 15115398
307: Xie Y, Yang HT, Cunanan C, Okamoto K, Shibata D, Pan J, Barnes DE, Lindahl T, McIlhatton M, Fishel R, Miller JH
Deficiencies in mouse Myh and Ogg1 result in tumor predisposition and G to T mutations in codon 12 of the K-ras oncogene in lung tumors.
Cancer Res 64: 3096-102 (2004)
PM ID: 15126346
308: Minagawa M, Deng Q, Liu ZX, Tsukamoto H, Dennert G
Activated natural killer T cells induce liver injury by Fas and tumor necrosis factor-alpha during alcohol consumption.
Gastroenterology 126: 1387-99 (2004)
PM ID: 15131799
309: Lenz HJ
The use and development of germline polymorphisms in clinical oncology.
J Clin Oncol 22: 2519-21 (2004)
PM ID: 15173210
310: Wallace K, Baron JA, Cole BF, Sandler RS, Karagas MR, Beach MA, Haile RW, Burke CA, Pearson LH, Mandel JS, Rothstein RI, Snover DC
Effect of calcium supplementation on the risk of large bowel polyps.
J Natl Cancer Inst 96: 921-5 (2004)
PM ID: 15199111
311: Lenz HJ
Molecular markers in gastrointestinal cancer: targeted therapy and tailored chemotherapy.
Onkologie 27: 12-4 (2004)
PM ID: 15017995
312: Hillenbrand A, Formentini A, Staib L, Sander S, Salonga D, Danenberg K, Danenberg P, Kornmann M
A longterm follow-up study of thymidylate synthase as a predictor for survival of patients with liver tumours receiving hepatic arterial infusion chemotherapy.
Eur J Surg Oncol 30: 407-13 (2004)
PM ID: 15063894
313: Widschwendter M, Siegmund KD, Müller HM, Fiegl H, Marth C, Müller-Holzner E, Jones PA, Laird PW
Association of breast cancer DNA methylation profiles with hormone receptor status and response to tamoxifen.
Cancer Res 64: 3807-13 (2004)
PM ID: 15172987
314: Ji C, Kaplowitz N
Hyperhomocysteinemia, endoplasmic reticulum stress, and alcoholic liver injury.
World J Gastroenterol 10: 1699-708 (2004)
PM ID: 15188490
315: Zheng YT, Li JZ, Ou JH
Regulation of hepatitis B virus core promoter by transcription factors HNF1 and HNF4 and the viral X protein.
J Virol 78: 6908-14 (2004)
PM ID: 15194767 PMC421633
316: Kaplowitz N
Acetaminophen hepatoxicity: what do we know, what don't we know, and what do we do next?
Hepatology 40: 23-6 (2004)
PM ID: 15239082
317: Stoehlmacher J, Park DJ, Zhang W, Yang D, Groshen S, Zahedy S, Lenz HJ
A multivariate analysis of genomic polymorphisms: prediction of clinical outcome to 5-FU/oxaliplatin combination chemotherapy in refractory colorectal cancer.
Br J Cancer 91: 344-54 (2004)
PM ID: 15213713 PMC2409815
318: Widschwendter M, Jiang G, Woods C, Müller HM, Fiegl H, Goebel G, Marth C, Müller-Holzner E, Zeimet AG, Laird PW, Ehrlich M
DNA hypomethylation and ovarian cancer biology.
Cancer Res 64: 4472-80 (2004)
PM ID: 15231656
319: Pike MC, Pearce CL, Peters RK, Cozen W, Wan P, Wu AH
Hormonal factors and the risk of invasive ovarian cancer: a population-based case-control study.
Fertil Steril 82: 186-95 (2004)
PM ID: 15237010
320: Hamoui N, Peters JH, Schneider S, Uchida K, Yang D, Vallböhmer D, Valboehmer D, Hagen JA, DeMeester SR, DeMeester TR, Danenberg K, Danenberg P
Increased acid exposure in patients with gastroesophageal reflux disease influences cyclooxygenase-2 gene expression in the squamous epithelium of the lower esophagus.
Arch Surg 139: 712-6; discussion 716-7 (2004)
PM ID: 15249402
321: Kimura T, Holland WS, Kawaguchi T, Williamson SK, Chansky K, Crowley JJ, Doroshow JH, Lenz HJ, Gandara DR, Gumerlock PH
Mutant DNA in plasma of lung cancer patients: potential for monitoring response to therapy.
Ann N Y Acad Sci 1022: 55-60 (2004)
PM ID: 15251940
322: Chen X, Park R, Shahinian AH, Bading JR, Conti PS
Pharmacokinetics and tumor retention of 125I-labeled RGD peptide are improved by PEGylation.
Nucl Med Biol 31: 11-9 (2004)
PM ID: 14741566
323: Alauddin MM, Shahinian A, Park R, Tohme M, Fissekis JD, Conti PS
Synthesis of 2'-deoxy-2'-[18F]fluoro-5-bromo-1-beta-D-arabinofuranosyluracil ([18F]-FBAU) and 2'-deoxy-2'-[18F]fluoro-5-chloro-1-beta-D-arabinofuranosyl-uracil ([18F]-FCAU), and their biological evaluation as markers for gene expression.
Nucl Med Biol 31: 399-405 (2004)
PM ID: 15093809
324: Bading JR, Shahinian AH, Vail A, Bathija P, Koszalka GW, Koda RT, Alauddin MM, Fissekis JD, Conti PS
Pharmacokinetics of the thymidine analog 2'-fluoro-5-methyl-1-beta-D-arabinofuranosyluracil (FMAU) in tumor-bearing rats.
Nucl Med Biol 31: 407-18 (2004)
PM ID: 15093810
325: Schneider S, Uchida K, Salonga D, Yochim JM, Danenberg KD, Danenberg PV
Quantitative determination of p16 gene expression by RT-PCR.
Methods Mol Biol 281: 91-103 (2004)
PM ID: 15220523
326: Chen X, Park R, Hou Y, Tohme M, Shahinian AH, Bading JR, Conti PS
microPET and autoradiographic imaging of GRP receptor expression with 64Cu-DOTA-[Lys3]bombesin in human prostate adenocarcinoma xenografts.
J Nucl Med 45: 1390-7 (2004)
PM ID: 15299066
327: Pike MC, Pearce CL, Wu AH
Prevention of cancers of the breast, endometrium and ovary.
Oncogene 23: 6379-91 (2004)
PM ID: 15322512
328: Danenberg PV
Pharmacogenomics of thymidylate synthase in cancer treatment.
Front Biosci 9: 2484-94 (2004)
PM ID: 15353301
329: Ji C, Deng Q, Kaplowitz N
Role of TNF-alpha in ethanol-induced hyperhomocysteinemia and murine alcoholic liver injury.
Hepatology 40: 442-51 (2004)
PM ID: 15368449
330: Uchida K, Hayashi K, Kawakami K, Schneider S, Yochim JM, Kuramochi H, Takasaki K, Danenberg KD, Danenberg PV
Loss of heterozygosity at the thymidylate synthase (TS) locus on chromosome 18 affects tumor response and survival in individuals heterozygous for a 28-bp polymorphism in the TS gene.
Clin Cancer Res 10: 433-9 (2004)
PM ID: 14760062
331: Schneider S, Yochim JM, Brabender J, Uchida K, Danenberg KD, Metzger R, Schneider PM, Salonga D, Hölscher AH, Danenberg PV
Osteopontin but not osteonectin messenger RNA expression is a prognostic marker in curatively resected non-small cell lung cancer.
Clin Cancer Res 10: 1588-96 (2004)
PM ID: 15014008
332: Brabender J, Lord RV, Metzger R, Park JM, Salonga D, Danenberg KD, Hölscher AH, Danenberg PV, Schneider PM
Role of retinoid X receptor mRNA expression in Barrett's esophagus.
J Gastrointest Surg 8: 413-22 (2004)
PM ID: 15120365
333: Park DJ, Lenz HJ
The role of proteasome inhibitors in solid tumors.
Ann Med 36: 296-303 (2004)
PM ID: 15224656
334: Chen X, Park R, Shahinian AH, Tohme M, Khankaldyyan V, Bozorgzadeh MH, Bading JR, Moats RA, Laug WE, Conti PS
18F-labeled RGD peptide: initial evaluation for imaging brain tumor angiogenesis.
Nucl Med Biol 31: 179-89 (2004)
PM ID: 15013483
335: Whitehead RP, Benedetti JK, Abbruzzese JL, Ardalan B, Goodwin JW, Balcerzak SP, Samlowski WE, Lenz HJ, Macdonald JS
A phase II study of high-dose 24 hour continuous infusion 5-FU and leucovorin and low-dose PALA for patients with advanced pancreatic adenocarcinoma: a Southwest Oncology Group Study.
Invest New Drugs 22: 335-41 (2004)
PM ID: 15122082
336: Sechi M, Angotzi G, Dallocchio R, Dessì A, Carta F, Sannia L, Mariani A, Fiori S, Sanchez TW, Movsessian L, Plasencia C, Neamati N
Design and synthesis of novel dihydroxyindole-2-carboxylic acids as HIV-1 integrase inhibitors.
Antivir Chem Chemother 15: 67-81 (2004)
PM ID: 15185725
337: Oakley-Girvan I, Feldman D, Eccleshall TR, Gallagher RP, Wu AH, Kolonel LN, Halpern J, Balise RR, West DW, Paffenbarger RS, Whittemore AS
Risk of early-onset prostate cancer in relation to germ line polymorphisms of the vitamin D receptor.
Cancer Epidemiol Biomarkers Prev 13: 1325-30 (2004)
PM ID: 15298953
338: Koehler SE, Ladner RD
Small interfering RNA-mediated suppression of dUTPase sensitizes cancer cell lines to thymidylate synthase inhibition.
Mol Pharmacol 66: 620-6 (2004)
PM ID: 15322254
339: Sechi M, Derudas M, Dallocchio R, Dessì A, Bacchi A, Sannia L, Carta F, Palomba M, Ragab O, Chan CK, Shoemaker R, Sei S, Dayam R, Neamati N
Design and synthesis of novel indole beta-diketo acid derivatives as HIV-1 integrase inhibitors.
J Med Chem 47: 5298-310 (2004)
PM ID: 15456274
340: Kaplowitz N
Statin-induced hepatotoxicity.
Gastroenterology 127: 1278; author reply 1278-9 (2004)
PM ID: 15481021
341: Kim MH, Trinh BN, Long TI, Oghamian S, Laird PW
Dnmt1 deficiency leads to enhanced microsatellite instability in mouse embryonic stem cells.
Nucleic Acids Res 32: 5742-9 (2004)
PM ID: 15509869 PMC528797
342: Chen X, Conti PS, Moats RA
In vivo near-infrared fluorescence imaging of integrin alphavbeta3 in brain tumor xenografts.
Cancer Res 64: 8009-14 (2004)
PM ID: 15520209
343: She H, Xiong S, Hazra S, Tsukamoto H
Adipogenic transcriptional regulation of hepatic stellate cells.
J Biol Chem 280: 4959-67 (2004)
PM ID: 15537655
344: Makhija MT, Kasliwal RT, Kulkarni VM, Neamati N
De novo design and synthesis of HIV-1 integrase inhibitors.
Bioorg Med Chem 12: 2317-33 (2004)
PM ID: 15080929
345: Nakayama K, Kanzaki A, Terada K, Mutoh M, Ogawa K, Sugiyama T, Takenoshita S, Itoh K, Yaegashi N, Miyazaki K, Neamati N, Takebayashi Y
Prognostic value of the Cu-transporting ATPase in ovarian carcinoma patients receiving cisplatin-based chemotherapy.
Clin Cancer Res 10: 2804-11 (2004)
PM ID: 15102688
346: Mandola MV, Stoehlmacher J, Zhang W, Groshen S, Yu MC, Iqbal S, Lenz HJ, Ladner RD
A 6 bp polymorphism in the thymidylate synthase gene causes message instability and is associated with decreased intratumoral TS mRNA levels.
Pharmacogenetics 14: 319-27 (2004)
PM ID: 15115918
347: Warnecke-Eberz U, Metzger R, Miyazono F, Baldus SE, Neiss S, Brabender J, Schaefer HF, Doerfler W, Bollschweiler E, Dienes HP, Mueller RP, Danenberg PV, Hoelscher AH, Schneider PM
High specificity of quantitative excision repair cross-complementing 1 messenger RNA expression for prediction of minor histopathological response to neoadjuvant radiochemotherapy in esophageal cancer.
Clin Cancer Res 10: 3794-9 (2004)
PM ID: 15173087
348: Gunawan BK, Kaplowitz N
Clinical perspectives on xenobiotic-induced hepatotoxicity.
Drug Metab Rev 36: 301-12 (2004)
PM ID: 15237856
349: Alauddin MM, Shahinian A, Gordon EM, Conti PS
Direct comparison of radiolabeled probes FMAU, FHBG, and FHPG as PET imaging agents for HSV1-tk expression in a human breast cancer model.
Mol Imaging 3: 76-84 (2004)
PM ID: 15296672
350: Chen X, Tohme M, Park R, Hou Y, Bading JR, Conti PS
Micro-PET imaging of alphavbeta3-integrin expression with 18F-labeled dimeric RGD peptide.
Mol Imaging 3: 96-104 (2004)
PM ID: 15296674
351: Iqbal S, Lenz HJ
Integration of novel agents in the treatment of colorectal cancer.
Cancer Chemother Pharmacol 54 Suppl 1: S32-9 (2004)
PM ID: 15309512
352: Chen X, Hou Y, Tohme M, Park R, Khankaldyyan V, Gonzales-Gomez I, Bading JR, Laug WE, Conti PS
Pegylated Arg-Gly-Asp peptide: 64Cu labeling and PET imaging of brain tumor alphavbeta3-integrin expression.
J Nucl Med 45: 1776-83 (2004)
PM ID: 15471848
353: Gunter MJ, Probst-Hensch NM, Cortessis VK, Kulldorff M, Haile RW, Sinha R
Meat intake, cooking-related mutagens and risk of colorectal adenoma in a sigmoidoscopy-based case-control study.
Carcinogenesis 26: 637-42 (2004)
PM ID: 15579480
354: Iqbal S, Stoehlmacher J, Lenz HJ
Tailored chemotherapy for colorectal cancer: a new approach to therapy.
Cancer Invest 22: 762-73 (2004)
PM ID: 15581057
355: Brabender J, Metzger R, Salonga D, Danenberg KD, Danenberg PV, Hölscher AH, Schneider PM
Comprehensive expression analysis of retinoic acid receptors and retinoid X receptors in non-small cell lung cancer: implications for tumor development and prognosis.
Carcinogenesis 26: 525-30 (2004)
PM ID: 15618235
356: Quach N, Goodman MF, Shibata D
In vitro mutation artifacts after formalin fixation and error prone translesion synthesis during PCR.
BMC Clin Pathol 4: 1 (2004)
PM ID: 15028125
357: Xiong S, She H, Tsukamoto H
Signaling role of iron in NF-kappa B activation in hepatic macrophages.
Comp Hepatol 3 Suppl 1: S36 (2004)
PM ID: 14960188
358: Brzozowski Z, Saczewski F, Sanchez TW, Kuo CL, Gdaniec M, Neamati N
Synthesis, antiviral, and anti-HIV-1 integrase activities of 3-aroyl-1,1-dioxo-1,4,2-benzodithiazines.
Bioorg Med Chem 12: 3663-72 (2005)
PM ID: 15186851
359: Garcia AA, Leichman L, Baranda J, Pandit L, Lenz HJ, Leichman CG
Phase II clinical trial of 5-fluorouracil, trimetrexate, and leucovorin (NFL) in patients with advanced pancreatic cancer.
Int J Gastrointest Cancer 34: 79-86 (2005)
PM ID: 15361639
360: Liu ZX, Govindarajan S, Kaplowitz N
Innate immune system plays a critical role in determining the progression and severity of acetaminophen hepatotoxicity.
Gastroenterology 127: 1760-74 (2005)
PM ID: 15578514
361: Irvine RA, Adachi N, Shibata DK, Cassell GD, Yu KJ, Karanjawala ZE, Hsieh CL, Lieber MR
Generation and characterization of endonuclease G null mice.
Mol Cell Biol 25: 294-302 (2005)
PM ID: 15601850 PMC538798
362: Easton DF, Hopper JL, Thomas DC, Antoniou A, Pharoah PD, Whittemore AS, Haile RW
Breast cancer risks for BRCA1/2 carriers.
Science 306: 2187-91; author reply 2187-91 (2005)
PM ID: 15622557
363: Pearce CL, Hirschhorn JN, Wu AH, Burtt NP, Stram DO, Young S, Kolonel LN, Henderson BE, Altshuler D, Pike MC
Clarifying the PROGINS allele association in ovarian and breast cancer risk: a haplotype-based analysis.
J Natl Cancer Inst 97: 51-9 (2005)
PM ID: 15632380
364: Wu AH, Arakawa K, Stanczyk FZ, Van Den Berg D, Koh WP, Yu MC
Tea and circulating estrogen levels in postmenopausal Chinese women in Singapore.
Carcinogenesis 26: 976-80 (2005)
PM ID: 15661801
365: Aiello F, Brizzi A, Garofalo A, Grande F, Ragno G, Dayam R, Neamati N
Synthesis of novel thiazolothiazepine based HIV-1 integrase inhibitors.
Bioorg Med Chem 12: 4459-66 (2005)
PM ID: 15265496
366: Lenz HJ
Pharmacogenomics and colorectal cancer.
Ann Oncol 15 Suppl 4: iv173-7 (2005)
PM ID: 15477304
367: Cham D, Henderson R, Conti PS
Virchow's node on F-18 FDG PET/CT.
Clin Nucl Med 29: 770-2 (2005)
PM ID: 15483511
368: Alauddin MM, Shahinian A, Park R, Tohme M, Fissekis JD, Conti PS
Synthesis and evaluation of 2'-deoxy-2'-18F-fluoro-5-fluoro-1-beta-D-arabinofuranosyluracil as a potential PET imaging agent for suicide gene expression.
J Nucl Med 45: 2063-9 (2005)
PM ID: 15585483
369: Dayam R, Sanchez TW, Clement O, Shoemaker R, Sei S, Neamati N
Beta-diketo acid pharmacophore hypothesis. 1. Discovery of a novel class of HIV-1 integrase inhibitors.
J Med Chem 48: 111-20 (2005)
PM ID: 15634005
370: Casey GR, Lindor NM, Papadopoulos N, Thibodeau SN, Moskow J, Steelman S, Buzin CH, Sommer SS, Collins CE, Butz M, Aronson M, Gallinger S, Barker MA, Young JP, Jass JR, Hopper JL, Diep AT, Bapat B, Salem M, Seminara D, Haile R, Colon Cancer Family Registry
Conversion analysis for mutation detection in MLH1 and MSH2 in patients with colorectal cancer.
JAMA 293: 799-809 (2005)
PM ID: 15713769
371: Kelley BD, Booth J, Tannatt M, Wub QL, Ladner RD, Yuc J, Potter D, Ley A
Isolation of a peptide ligand for affinity purification of factor VIII using phage display.
J Chromatogr A 1038: 121-30 (2005)
PM ID: 15233528
372: Chi G, Neamati N, Nair V
Inhibition of the strand transfer step of HIV-1 integrase by non-natural dinucleotides.
Bioorg Med Chem Lett 14: 4815-7 (2005)
PM ID: 15341930
373: Chen X, Liu S, Hou Y, Tohme M, Park R, Bading JR, Conti PS
MicroPET imaging of breast cancer alphav-integrin expression with 64Cu-labeled dimeric RGD peptides.
Mol Imaging Biol 6: 350-9 (2005)
PM ID: 15380745
374: Jadvar H, Gamie S, Ramanna L, Conti PS
Musculoskeletal system.
Semin Nucl Med 34: 254-61 (2005)
PM ID: 15493003
375: Jadvar H, Conti PS
The reproductive tract.
Semin Nucl Med 34: 262-73 (2005)
PM ID: 15493004
376: Theisen J, Peters JH, Fein M, Hughes M, Hagen JA, DeMeester SR, DeMeester TR, Laird PW
The mutagenic potential of duodenoesophageal reflux.
Ann Surg 241: 63-8 (2005)
PM ID: 15621992 PMC1356847
377: Nathwani RA, Pais S, Reynolds TB, Kaplowitz N
Serum alanine aminotransferase in skeletal muscle diseases.
Hepatology 41: 380-2 (2005)
PM ID: 15660433
378: Nathwani RA, Kumar SR, Reynolds TB, Kaplowitz N
Marked elevation in serum transaminases: an atypical presentation of choledocholithiasis.
Am J Gastroenterol 100: 295-8 (2005)
PM ID: 15667485
379: Tung KH, Wilkens LR, Wu AH, McDuffie K, Nomura AM, Kolonel LN, Terada KY, Goodman MT
Effect of anovulation factors on pre- and postmenopausal ovarian cancer risk: revisiting the incessant ovulation hypothesis.
Am J Epidemiol 161: 321-9 (2005)
PM ID: 15692075
380: Lenz HJ
Angiogenesis as a target in colorectal cancer therapy. Introduction.
Semin Oncol 31: 1-2 (2005)
PM ID: 15696023
381: Iqbal S, Lenz HJ
Angiogenesis inhibitors in the treatment of colorectal cancer.
Semin Oncol 31: 10-6 (2005)
PM ID: 15696025
382: Schneider S, Uchida K, Brabender J, Baldus SE, Yochim JM, Danenberg KD, Salonga D, Chen PC, Tsao-Wei DD, Groshen S, Hoelscher AH, Schneider PM, Danenberg PV
Downregulation of TS, DPD, ERCC1, GST-Pi, EGFR, and HER2 gene expression after neoadjuvant three-modality treatment in patients with esophageal cancer.
J Am Coll Surg 200: 336-44 (2005)
PM ID: 15737843
383: Cote RJ, Laird PW, Datar RH
Promoter hypermethylation: a new therapeutic target emerges in urothelial cancer.
J Clin Oncol 23: 2879-81 (2005)
PM ID: 15753457
384: Tsou JA, Shen LY, Siegmund KD, Long TI, Laird PW, Seneviratne CK, Koss MN, Pass HI, Hagen JA, Laird-Offringa IA
Distinct DNA methylation profiles in malignant mesothelioma, lung adenocarcinoma, and non-tumor lung.
Lung Cancer 47: 193-204 (2005)
PM ID: 15639718
385: Falk RT, Fears TR, Xu X, Hoover RN, Pike MC, Wu AH, Nomura AM, Kolonel LN, West DW, Sepkovic DW, Bradlow HL, Ziegler RG
Urinary estrogen metabolites and their ratio among Asian American women.
Cancer Epidemiol Biomarkers Prev 14: 221-6 (2005)
PM ID: 15668498
386: Chen X, Plasencia C, Hou Y, Neamati N
Synthesis and biological evaluation of dimeric RGD peptide-paclitaxel conjugate as a model for integrin-targeted drug delivery.
J Med Chem 48: 1098-106 (2005)
PM ID: 15715477
387: Sechi M, Sannia L, Carta F, Palomba M, Dallocchio R, Dessì A, Derudas M, Zawahir Z, Neamati N
Design of novel bioisosteres of beta-diketo acid inhibitors of HIV-1 integrase.
Antivir Chem Chemother 16: 41-61 (2005)
PM ID: 15739621
388: Deng J, Lee KW, Sanchez TW, Cui M, Neamati N, Briggs JM
Dynamic receptor-based pharmacophore model development and its application in designing novel HIV-1 integrase inhibitors.
J Med Chem 48: 1496-505 (2005)
PM ID: 15743192
389: Garcia AA, Pujari M, Jeffers S, Iqbal S, Lenz HJ, Beringer P, Louie SG
Phase I clinical and pharmacokinetic trial of docetaxel and irinotecan administered on a weekly schedule.
Cancer Chemother Pharmacol 56: 75-82 (2005)
PM ID: 15809878
390: Lindor NM, Rabe K, Petersen GM, Haile R, Casey GR, Baron JA, Gallinger S, Bapat B, Aronson M, Hopper JL, Jass J, LeMarchand L, Grove J, Potter JD, Newcomb P, Terdiman JP, Conrad P, Moslein G, Goldberg R, Ziogas A, Anton-Culver H, de Andrade M, Siegmund KD, Thibodeau SN, Boardman LA, Seminara D
Lower cancer incidence in Amsterdam-I criteria families without mismatch repair deficiency: familial colorectal cancer type X.
JAMA 293: 1979-85 (2005)
PM ID: 15855431
391: Francis GS, Kaplowitz N, Alteri E
Liver injury associated with the beta-interferons for MS.
Neurology 63: 1142-3; author reply 1142-3 (2005)
PM ID: 15457586
392: Dayam R, Neamati N
Active site binding modes of the beta-diketoacids: a multi-active site approach in HIV-1 integrase inhibitor design.
Bioorg Med Chem 12: 6371-81 (2005)
PM ID: 15556755
393: Neff GW, Reddy KR, Durazo FA, Meyer D, Marrero R, Kaplowitz N
Severe hepatotoxicity associated with the use of weight loss diet supplements containing ma huang or usnic acid.
J Hepatol 41: 1062-4 (2005)
PM ID: 15582145
394: Kuramochi H, Vallböhmer D, Uchida K, Schneider S, Hamoui N, Shimizu D, Chandrasoma PT, DeMeester TR, Danenberg KD, Danenberg PV, Peters JH
Quantitative, tissue-specific analysis of cyclooxygenase gene expression in the pathogenesis of Barrett's adenocarcinoma.
J Gastrointest Surg 8: 1007-16; discussion 1016-7 (2005)
PM ID: 15585388
395: Zhang W, Park DJ, Lu B, Yang DY, Gordon M, Groshen S, Yun JE, Press OA, Vallböhmer D, Rhodes K, Lenz HJ
Epidermal growth factor receptor gene polymorphisms predict pelvic recurrence in patients with rectal cancer treated with chemoradiation.
Clin Cancer Res 11: 600-5 (2005)
PM ID: 15701846
396: Lara PN, Law LY, Wright JJ, Frankel P, Twardowski P, Lenz HJ, Lau DH, Kawaguchi T, Gumerlock PH, Doroshow JH, Gandara DR
Intermittent dosing of the farnesyl transferase inhibitor tipifarnib (R115777) in advanced malignant solid tumors: a phase I California Cancer Consortium Trial.
Anticancer Drugs 16: 317-21 (2005)
PM ID: 15711184
397: Garcia AA, Blessing JA, Lenz HJ, Darcy KM, Mannel RS, Miller DS, Husseinzadeh N, Gynecologic Oncology Group
Phase II clinical trial of capecitabine in ovarian carcinoma recurrent 6-12 months after completion of primary chemotherapy, with exploratory TS, DPD, and TP correlates: a Gynecologic Oncology Group study.
Gynecol Oncol 96: 810-7 (2005)
PM ID: 15721430
398: Conti PS
The future of radioimmunotherapy: a PET perspective.
Semin Oncol 32: S63-7 (2005)
PM ID: 15786028
399: Mack TM
The ghost of pandemics past.
Lancet 365: 1370-2 (2005)
PM ID: 15836872
400: Cozen W, Diaz-Sanchez D, James Gauderman W, Zadnick J, Cockburn MG, Gill PS, Masood R, Hamilton AS, Jyrala M, Mack TM
Th1 and Th2 cytokines and IgE levels in identical twins with varying levels of cigarette consumption.
J Clin Immunol 24: 617-22 (2005)
PM ID: 15622446
401: Sussman S, Runyon BA, Hernandez R, Magallanes M, Mendler MH, Yuan JM, Tsukamoto H
A pilot study of an alcoholic liver disease recurrence prevention education program in hospitalized patients with advanced liver disease.
Addict Behav 30: 465-73 (2005)
PM ID: 15718064
402: Joshi MB, Shirota Y, Danenberg KD, Conlon DH, Salonga DS, Herndon JE, Danenberg PV, Harpole DH
High gene expression of TS1, GSTP1, and ERCC1 are risk factors for survival in patients treated with trimodality therapy for esophageal cancer.
Clin Cancer Res 11: 2215-21 (2005)
PM ID: 15788669
403: Fernandez-Checa JC, Kaplowitz N
Hepatic mitochondrial glutathione: transport and role in disease and toxicity.
Toxicol Appl Pharmacol 204: 263-73 (2005)
PM ID: 15845418
404: Wu AH, Stanczyk FZ, Martinez C, Tseng CC, Hendrich S, Murphy P, Chaikittisilpa S, Stram DO, Pike MC
A controlled 2-mo dietary fat reduction and soy food supplementation study in postmenopausal women.
Am J Clin Nutr 81: 1133-41 (2005)
PM ID: 15883439
405: Vallböhmer D, Zhang W, Gordon M, Yang DY, Yun JE, Press OA, Rhodes KE, Sherrod AE, Iqbal S, Danenberg KD, Groshen S, Lenz HJ
Molecular determinants of cetuximab efficacy.
J Clin Oncol 23: 3536-44 (2005)
PM ID: 15908664
406: Sarter B, Long TI, Tsong WH, Koh WP, Yu MC, Laird PW
Sex differential in methylation patterns of selected genes in Singapore Chinese.
Hum Genet 117: 402-3 (2005)
PM ID: 15928902
407: Kim JY, Beart RW, Shibata D
Stability of colon stem cell methylation after neo-adjuvant therapy in a patient with attenuated familial adenomatous polyposis.
BMC Gastroenterol 5: 19 (2005)
PM ID: 15941485 PMC1164411
408: Kim JY, Siegmund KD, Tavaré S, Shibata D
Age-related human small intestine methylation: evidence for stem cell niches.
BMC Med 3: 10 (2005)
PM ID: 15975143 PMC1168897
409: Ursin G, Hovanessian-Larsen L, Parisky YR, Pike MC, Wu AH
Greatly increased occurrence of breast cancers in areas of mammographically dense tissue.
Breast Cancer Res 7: R605-8 (2005)
PM ID: 16168104 PMC1242126
410: Kabbarah O, Sotelo AK, Mallon MA, Winkeler EL, Fan MY, Pfeifer JD, Shibata D, Gutmann DH, Goodfellow PJ
Diethylstilbestrol effects and lymphomagenesis in Mlh1-deficient mice.
Int J Cancer 115: 666-9 (2005)
PM ID: 15700306
411: Stern MC, Siegmund KD, Corral R, Haile RW
XRCC1 and XRCC3 polymorphisms and their role as effect modifiers of unsaturated fatty acids and antioxidant intake on colorectal adenomas risk.
Cancer Epidemiol Biomarkers Prev 14: 609-15 (2005)
PM ID: 15767338
412: Tung KH, Wilkens LR, Wu AH, McDuffie K, Hankin JH, Nomura AM, Kolonel LN, Goodman MT
Association of dietary vitamin A, carotenoids, and other antioxidants with the risk of ovarian cancer.
Cancer Epidemiol Biomarkers Prev 14: 669-76 (2005)
PM ID: 15767348
413: Chen X, Sievers E, Hou Y, Park R, Tohme M, Bart R, Bremner R, Bading JR, Conti PS
Integrin alpha v beta 3-targeted imaging of lung cancer.
Neoplasia 7: 271-9 (2005)
PM ID: 15799827 PMC1501139
414: Haile RW, Yochim JM, Cortessis VK, Lin J, Levine AJ, Diep AT, Danenberg K, Danenberg P
A molecular/epidemiologic analysis of expression of cyclooxygenases 1 and 2, use of nonsteroidal antiinflammatory drugs, and risk of colorectal adenoma.
Clin Colorectal Cancer 4: 390-5 (2005)
PM ID: 15807932
415: Laird PW
Cancer epigenetics.
Hum Mol Genet 14 Spec No 1: R65-76 (2005)
PM ID: 15809275
416: Vallbohmer D, Lenz HJ
Epidermal growth factor receptor as a target for chemotherapy.
Clin Colorectal Cancer 5 Suppl 1: S19-27 (2005)
PM ID: 15871762
417: Hogan S, Rookey K, Ladner RD
URSA: ultra rapid selection of antibodies from an antibody phage display library.
Biotechniques 38: 536, 538 (2005)
PM ID: 15884669
418: Kakimoto M, Uetake H, Osanai T, Shirota Y, Takagi Y, Takeshita E, Toriya Y, Danenberg K, Danenberg PV, Sugihara K
Thymidylate synthase and dihydropyrimidine dehydrogenase gene expression in breast cancer predicts 5-FU sensitivity by a histocultural drug sensitivity test.
Cancer Lett 223: 103-11 (2005)
PM ID: 15890242
419: Kaplowitz N
Idiosyncratic drug hepatotoxicity.
Nat Rev Drug Discov 4: 489-99 (2005)
PM ID: 15931258
420: Uchida K, Schneider S, Yochim JM, Kuramochi H, Hayashi K, Takasaki K, Yang D, Danenberg KD, Danenberg PV
Intratumoral COX-2 gene expression is a predictive factor for colorectal cancer response to fluoropyrimidine-based chemotherapy.
Clin Cancer Res 11: 3363-8 (2005)
PM ID: 15867236
421: Lenz HJ
Antiangiogenic agents in cancer therapy.
Oncology (Williston Park) 19: 17-25 (2005)
PM ID: 15934499
422: Meadows DC, Mathews TB, North TW, Hadd MJ, Kuo CL, Neamati N, Gervay-Hague J
Synthesis and biological evaluation of geminal disulfones as HIV-1 integrase inhibitors.
J Med Chem 48: 4526-34 (2005)
PM ID: 15999991
423: Coleman RE, Delbeke D, Guiberteau MJ, Conti PS, Royal HD, Weinreb JC, Siegel BA, Federle MF, Townsend DW, Berland LL, American College of Radiology , Society of Nuclear Medicine , Society of Computed Body Tomography and Magnetic R
Concurrent PET/CT with an integrated imaging system: intersociety dialogue from the joint working group of the American College of Radiology, the Society of Nuclear Medicine, and the Society of Computed Body Tomography and Magnetic Resonance.
J Nucl Med 46: 1225-39 (2005)
PM ID: 16000293
424: Thomas DC, Haile RW, Duggan DJ
Recent developments in genomewide association scans: a workshop summary and review.
Am J Hum Genet 77: 337-45 (2005)
PM ID: 16080110 PMC1226200
425: Lenz HJ
First Amsterdam, then Bethesda, now Melbourne?
J Clin Oncol 23: 6445-9 (2005)
PM ID: 16116155
426: Zheng YT, Fu XD, Ou JH
Suppression of hepatitis B virus replication by SRPK1 and SRPK2 via a pathway independent of the phosphorylation of the viral core protein.
Virology 342: 150-8 (2005)
PM ID: 16122776
427: Robertson DJ, Greenberg ER, Beach M, Sandler RS, Ahnen DJ, Haile RW, Burke CA, Snover DC, Bresalier RS, McKeown-Eyssen GE, Mandel JS, Bond JH, Van Stolk RU, Summers RW, Rothstein RI, Church TR, Cole BF, Byers T, Mott L, Baron JA
Colorectal cancer in patients under close colonoscopic surveillance.
Gastroenterology 129: 34-41 (2005)
PM ID: 16012932
428: Jadvar H, Xiankui L, Shahinian A, Park R, Tohme M, Pinski J, Conti PS
Glucose metabolism of human prostate cancer mouse xenografts.
Mol Imaging 4: 91-7 (2005)
PM ID: 16105512
429: Calabrese P, Mecklin JP, Järvinen HJ, Aaltonen LA, Tavaré S, Shibata D
Numbers of mutations to different types of colorectal cancer.
BMC Cancer 5: 126 (2005)
PM ID: 16202134 PMC1266026
430: Yavrom S, Chen L, Xiong S, Wang JG, Rippe RA, Tsukamoto H
Peroxisome proliferator-activated receptor gamma suppresses proximal alpha1(I) collagen promoter via inhibition of p300-facilitated NF-I binding to DNA in hepatic stellate cells.
J Biol Chem 280: 40650-9 (2005)
PM ID: 16216869
431: Zhao Q, Ma L, Jiang S, Lu H, Liu S, He Y, Strick N, Neamati N, Debnath AK
Identification of N-phenyl-N'-(2,2,6,6-tetramethyl-piperidin-4-yl)-oxalamides as a new class of HIV-1 entry inhibitors that prevent gp120 binding to CD4.
Virology 339: 213-25 (2005)
PM ID: 15996703
432: Brabender J, Marjoram P, Lord RV, Metzger R, Salonga D, Vallböhmer D, Schäfer H, Danenberg KD, Danenberg PV, Selaru FM, Baldus SE, Hölscher AH, Meltzer SJ, Schneider PM
The molecular signature of normal squamous esophageal epithelium identifies the presence of a field effect and can discriminate between patients with Barrett's esophagus and patients with Barrett's-associated adenocarcinoma.
Cancer Epidemiol Biomarkers Prev 14: 2113-7 (2005)
PM ID: 16172218
433: Deng QG, She H, Cheng JH, French SW, Koop DR, Xiong S, Tsukamoto H
Steatohepatitis induced by intragastric overfeeding in mice.
Hepatology 42: 905-14 (2005)
PM ID: 16175602
434: Vallböhmer D, Peters JH, Oh D, Kuramochi H, Shimizu D, DeMeester SR, Hagen JA, Chandrasoma PT, Danenberg KD, DeMeester TR, Danenberg P
Survivin, a potential biomarker in the development of Barrett's adenocarcinoma.
Surgery 138: 701-6; discussion 706-7 (2005)
PM ID: 16269299
435: Chaudhari AJ, Darvas F, Bading JR, Moats RA, Conti PS, Smith DJ, Cherry SR, Leahy RM
Hyperspectral and multispectral bioluminescence optical tomography for small animal imaging.
Phys Med Biol 50: 5421-41 (2005)
PM ID: 16306643
436: Kim JY, Tavaré S, Shibata D
Counting human somatic cell replications: methylation mirrors endometrial stem cell divisions.
Proc Natl Acad Sci U S A 102: 17739-44 (2005)
PM ID: 16314580 PMC1308885
437: Woodson K, Weisenberger DJ, Campan M, Laird PW, Tangrea J, Johnson LL, Schatzkin A, Lanza E
Gene-specific methylation and subsequent risk of colorectal adenomas among participants of the polyp prevention trial.
Cancer Epidemiol Biomarkers Prev 14: 1219-23 (2005)
PM ID: 15894675
438: Miyoshi Y, Uemura H, Ishiguro H, Kitamura H, Nomura N, Danenberg PV, Kubota Y
Expression of thymidylate synthase, dihydropyrimidine dehydrogenase, thymidine phosphorylase, and orotate phosphoribosyl transferase in prostate cancer.
Prostate Cancer Prostatic Dis 8: 260-5 (2005)
PM ID: 15999119
439: Shimizu D, Ishikawa T, Ichikawa Y, Togo S, Hayasizaki Y, Okazaki Y, Danenberg PV, Shimada H
Prediction of chemosensitivity of colorectal cancer to 5-fluorouracil by gene expression profiling with cDNA microarrays.
Int J Oncol 27: 371-6 (2005)
PM ID: 16010417
440: Plasencia C, Dayam R, Wang QS, Pinski J, Burke TR, Quinn DI, Neamati N
Discovery and preclinical evaluation of a novel class of small-molecule compounds in hormone-dependent and -independent cancer cell lines.
Mol Cancer Ther 4: 1105-13 (2005)
PM ID: 16020668
441: Grau MV, Baron JA, Barry EL, Sandler RS, Haile RW, Mandel JS, Cole BF
Interaction of calcium supplementation and nonsteroidal anti-inflammatory drugs and the risk of colorectal adenomas.
Cancer Epidemiol Biomarkers Prev 14: 2353-8 (2005)
PM ID: 16214916
442: Park DJ, Zhang W, Stoehlmacher J, Tsao-Wei DD, Groshen S, Gil J, Yun JE, Sones E, Mallik N, Lenz HJ
ERCC1 gene polymorphism as a predictor for clinical outcome in advanced colorectal cancer patients treated with platinum-based chemotherapy.
Clin Adv Hematol Oncol 1: 162-6 (2005)
PM ID: 16224397
443: Weisenberger DJ, Campan M, Long TI, Kim MH, Woods C, Fiala E, Ehrlich M, Laird PW
Analysis of repetitive element DNA methylation by MethyLight.
Nucleic Acids Res 33: 6823-36 (2005)
PM ID: 16326863 PMC1301596
444: Yang MD, Deng QG, Chen SP, Xiong S, Koop DR, Tsukamoto H
Hepatoprotective mechanisms of Yan-gan-wan.
Hepatol Res 32: 202-212 (2005)
PM ID: 16107322
445: Clark JW, Eder JP, Ryan DP, Lathia C, Lenz HJ
Safety and pharmacokinetics of the dual action Raf kinase and vascular endothelial growth factor receptor inhibitor, BAY 43-9006, in patients with advanced, refractory solid tumors.
Clin Cancer Res 11: 5472-80 (2006)
PM ID: 16061863
446: Ji C, Mehrian-Shai R, Chan CK, Hsu YH, Kaplowitz N
Role of CHOP in hepatic apoptosis in the murine model of intragastric ethanol feeding.
Alcohol Clin Exp Res 29: 1496-503 (2006)
PM ID: 16131858 PMC1432051 NIHMS7801
447: Cockburn MG, Wu AH, Bernstein L
Etiologic clues from the similarity of histology-specific trends in esophageal and lung cancers.
Cancer Causes Control 16: 1065-74 (2006)
PM ID: 16184472
448: Lord RV, Brabender J, Wickramasinghe K, DeMeester SR, Holscher A, Schneider PM, Danenberg PV, DeMeester TR
Increased CDX2 and decreased PITX1 homeobox gene expression in Barrett's esophagus and Barrett's-associated adenocarcinoma.
Surgery 138: 924-31 (2006)
PM ID: 16291394
449: Attar M, Ling KH, Tang-Liu DD, Neamati N, Lee VH
Cytochrome P450 3A expression and activity in the rabbit lacrimal gland: glucocorticoid modulation and the impact on androgen metabolism.
Invest Ophthalmol Vis Sci 46: 4697-706 (2006)
PM ID: 16303967
450: Tsukamoto H
Adipogenic phenotype of hepatic stellate cells.
Alcohol Clin Exp Res 29: 132S-133S (2006)
PM ID: 16344597
451: Robertson DJ, Sandler RS, Haile R, Tosteson TD, Greenberg ER, Grau M, Baron JA
Fat, fiber, meat and the risk of colorectal adenomas.
Am J Gastroenterol 100: 2789-95 (2006)
PM ID: 16393237
452: Brzozowski Z, Saczewski F, Neamati N
Synthesis, antitumor and anti-HIV activities of benzodithiazine-dioxides.
Bioorg Med Chem 14: 2985-93 (2006)
PM ID: 16406643
453: Ogino S, Cantor M, Kawasaki T, Brahmandam M, Kirkner GJ, Weisenberger DJ, Campan M, Laird PW, Loda M, Fuchs CS
CpG island methylator phenotype (CIMP) of colorectal cancer is best characterised by quantitative DNA methylation analysis and prospective cohort studies.
Gut 55: 1000-6 (2006)
PM ID: 16407376 PMC1856352
454: Nair V, Uchil V, Neamati N
Beta-diketo acids with purine nucleobase scaffolds: novel, selective inhibitors of the strand transfer step of HIV integrase.
Bioorg Med Chem Lett 16: 1920-3 (2006)
PM ID: 16439124
455: Whitehead RP, McCoy S, Macdonald JS, Rivkin SE, Neubauer MA, Dakhil SR, Lenz HJ, Tanaka MS, Abbruzzese JL
Phase II trial of R115777 (NSC #70818) in patients with advanced colorectal cancer: A Southwest Oncology Group study.
Invest New Drugs E publication ahead of print: (2006)
PM ID: 16444612
456: Iqbal S, Lenz HJ
Capecitabine: the new generation of fluoropyrimidines in colorectal cancer.
Expert Rev Anticancer Ther 4: 947-55 (2006)
PM ID: 15606325
457: Cui Y, Morgenstern H, Greenland S, Tashkin DP, Mao JT, Cao W, Cozen W, Mack TM, Zhang ZF
Polymorphism of Xeroderma Pigmentosum group G and the risk of lung cancer and squamous cell carcinomas of the oropharynx, larynx and esophagus.
Int J Cancer 118: 714-20 (2006)
PM ID: 16094634
458: Leichman CG, Benedetti JK, Zalupski MM, Hochster HS, Shields AF, Lenz HJ, Wade Iii JL, Bearden Iii JD, Macdonald JS
Assessment of infusional 5-fluorouracil schedule and dose intensity: a Southwest Oncology Group and Eastern Cooperative Oncology Group study.
Clin Colorectal Cancer 5: 119-23 (2006)
PM ID: 16098253
459: Zhang W, Stoehlmacher J, Park DJ, Yang D, Borchard E, Gil J, Tsao-Wei DD, Yun JE, Gordon M, Press OA, Rhodes K, Groshen S, Lenz HJ
Gene polymorphisms of epidermal growth factor receptor and its downstream effector, interleukin-8, predict oxaliplatin efficacy in patients with advanced colorectal cancer.
Clin Colorectal Cancer 5: 124-31 (2006)
PM ID: 16098254
460: Vigen C, Bernstein L, Wu AH
Occupational physical activity and risk of adenocarcinomas of the esophagus and stomach.
Int J Cancer 118: 1004-9 (2006)
PM ID: 16152595
461: Conti PS, White C, Pieslor P, Molina A, Aussie J, Foster P
The role of imaging with (111)In-ibritumomab tiuxetan in the ibritumomab tiuxetan (zevalin) regimen: results from a Zevalin Imaging Registry.
J Nucl Med 46: 1812-8 (2006)
PM ID: 16269594
462: Dayam R, Sanchez TW, Neamati N
Diketo acid pharmacophore. 2. Discovery of structurally diverse inhibitors of HIV-1 integrase.
J Med Chem 48: 8009-15 (2006)
PM ID: 16335925
463: Gordon MA, Gil J, Lu B, Zhang W, Yang D, Yun JE, Schneider S, Groshen S, Iqbal S, Press OA, Rhodes K, Lenz HJ
Genomic profiling associated with recurrence in patients with rectal cancer treated with chemoradiation.
Pharmacogenomics 7: 67-88 (2006)
PM ID: 16354126
464: Venook AP, Blanke CD, Niedzwiecki D, Lenz HJ, Taylor JR, Hollis DR, Sutherland S, Goldberg RM
Cancer and Leukemia Group B/Southwest Oncology Group trial 80405: a phase III trial of chemotherapy and biologics for patients with untreated advanced colorectal adenocarcinoma.
Clin Colorectal Cancer 5: 292-4 (2006)
PM ID: 16356309
465: Gago-Dominguez M, Castelao JE, Pike MC, Sevanian A, Haile RW
Role of lipid peroxidation in the epidemiology and prevention of breast cancer.
Cancer Epidemiol Biomarkers Prev 14: 2829-39 (2006)
PM ID: 16364997
466: Kuramochi H, Hayashi K, Uchida K, Miyakura S, Shimizu D, Vallböhmer D, Park SY, Danenberg KD, Takasaki K, Danenberg PV
Vascular endothelial growth factor messenger RNA expression level is preserved in liver metastases compared with corresponding primary colorectal cancer.
Clin Cancer Res 12: 29-33 (2006)
PM ID: 16397020
467: Fiegl H, Millinger S, Goebel G, Müller-Holzner E, Marth C, Laird PW, Widschwendter M
Breast cancer DNA methylation profiles in cancer cells and tumor stroma: association with HER-2/neu status in primary breast cancer.
Cancer Res 66: 29-33 (2006)
PM ID: 16397211
468: Ajani JA, Lee FC, Singh DA, Haller DG, Lenz HJ, Benson AB, Yanagihara R, Phan AT, Yao JC, Strumberg D
Multicenter phase II trial of S-1 plus cisplatin in patients with untreated advanced gastric or gastroesophageal junction adenocarcinoma.
J Clin Oncol 24: 663-7 (2006)
PM ID: 16446338
469: Deng J, Kelley JA, Barchi JJ, Sanchez TW, Dayam R, Pommier Y, Neamati N
Mining the NCI antiviral compounds for HIV-1 integrase inhibitors.
Bioorg Med Chem 14: 3785-92 (2006)
PM ID: 16460953
470: Burd CJ, Petre CE, Morey LM, Wang Y, Revelo MP, Haiman CA, Lu SC, Fenoglio-Preiser CM, Li JZ, Knudsen ES, Wong J, Knudsen KE
Cyclin D1b variant influences prostate cancer growth through aberrant androgen receptor regulation.
Proc Natl Acad Sci U S A 103: 2190-5 (2006)
PM ID: 16461912 PMC1413684
471: Han D, Hanawa N, Saberi B, Kaplowitz N
Mechanisms of liver injury. III. Role of glutathione redox status in liver injury.
Am J Physiol Gastrointest Liver Physiol 291: G1-7 (2006)
PM ID: 16500922
472: Kemeny NE, Niedzwiecki D, Hollis DR, Lenz HJ, Warren RS, Naughton MJ, Weeks JC, Sigurdson ER, Herndon JE, Zhang C, Mayer RJ
Hepatic arterial infusion versus systemic therapy for hepatic metastases from colorectal cancer: a randomized trial of efficacy, quality of life, and molecular markers (CALGB 9481).
J Clin Oncol 24: 1395-403 (2006)
PM ID: 16505413
473: Macdonald JS, McCoy S, Whitehead RP, Iqbal S, Wade JL, Giguere JK, Abbruzzese JL
A phase II study of farnesyl transferase inhibitor R115777 in pancreatic cancer: a Southwest oncology group (SWOG 9924) study.
Invest New Drugs 23: 485-7 (2006)
PM ID: 16133800
474: Nair V, Chi G, Ptak R, Neamati N
HIV integrase inhibitors with nucleobase scaffolds: discovery of a highly potent anti-HIV agent.
J Med Chem 49: 445-7 (2006)
PM ID: 16420027 PMC2518396 NIHMS63135
475: Barry EL, Baron JA, Grau MV, Wallace K, Haile RW
K-ras mutations in incident sporadic colorectal adenomas.
Cancer 106: 1036-40 (2006)
PM ID: 16456810
476: Chen X, Park R, Khankaldyyan V, Gonzales-Gomez I, Tohme M, Moats RA, Bading JR, Laug WE, Conti PS
Longitudinal microPET imaging of brain tumor growth with F-18-labeled RGD peptide.
Mol Imaging Biol 8: 9-15 (2006)
PM ID: 16315003
477: Garcia AA, Iqbal S, Quinn DI, Edwards SM, Lenz HJ, Weber JS
Phase I clinical trial of weekly docetaxel and exisulind, a novel inducer of apoptosis.
Invest New Drugs 24: 79-83 (2006)
PM ID: 16379039
478: Kaplowitz N
Liver biology and pathobiology.
Hepatology 43: S235-8 (2006)
PM ID: 16447293
479: El-Khoueiry AB, Lenz HJ
Should continuous infusion 5-fluorouracil become the standard of care in the USA as it is in Europe?
Cancer Invest 24: 50-5 (2006)
PM ID: 16466993
480: Wu AH, Yu MC
Tea, hormone-related cancers and endogenous hormone levels.
Mol Nutr Food Res 50: 160-9 (2006)
PM ID: 16470648
481: Deng J, Sanchez TW, Neamati N, Briggs JM
Dynamic pharmacophore model optimization: identification of novel HIV-1 integrase inhibitors.
J Med Chem 49: 1684-92 (2006)
PM ID: 16509584
482: Odin E, Wettergren Y, Carlsson G, Danenberg PV, Termini A, Willén R, Gustavsson B
Expression and clinical significance of methylenetetrahydrofolate reductase in patients with colorectal cancer.
Clin Colorectal Cancer 5: 344-9 (2006)
PM ID: 16512993
483: Hawes D, Downey S, Pearce CL, Bartow S, Wan P, Pike MC, Wu AH
Dense breast stromal tissue shows greatly increased concentration of breast epithelium but no increase in its proliferative activity.
Breast Cancer Res 8: R24 (2006)
PM ID: 16646977 PMC1557710
484: Lara PN, Stadler WM, Longmate J, Quinn DI, Wexler J, Van Loan M, Twardowski P, Gumerlock PH, Vogelzang NJ, Vokes EE, Lenz HJ, Doroshow JH, Gandara DR
A randomized phase II trial of the matrix metalloproteinase inhibitor BMS-275291 in hormone-refractory prostate cancer patients with bone metastases.
Clin Cancer Res 12: 1556-63 (2006)
PM ID: 16533781
485: Vallböhmer D, Peters JH, Kuramochi H, Oh D, Yang D, Shimizu D, DeMeester SR, Hagen JA, Chandrasoma PT, Danenberg KD, Danenberg PV, DeMeester TR
Molecular determinants in targeted therapy for esophageal adenocarcinoma.
Arch Surg 141: 476-81; discussion 481-2 (2006)
PM ID: 16702519
486: Han D, Hanawa N, Saberi B, Kaplowitz N
Hydrogen peroxide and redox modulation sensitize primary mouse hepatocytes to TNF-induced apoptosis.
Free Radic Biol Med 41: 627-39 (2006)
PM ID: 16863996
487: Karagas MR, Zens MS, Stukel TA, Swerdlow AJ, Rosso S, Osterlind A, Mack TM, Kirkpatrick CS, Holly EA, Green AC, Gallagher RP, Elwood JM, Armstrong BK
Pregnancy history and incidence of melanoma in women: a pooled analysis.
Cancer Causes Control 17: 11-9 (2006)
PM ID: 16411048
488: Ehrlich M, Woods CB, Yu MC, Dubeau L, Yang F, Campan M, Weisenberger DJ, Long TI, Youn B, Fiala ES, Laird PW
Quantitative analysis of associations between DNA hypermethylation, hypomethylation, and DNMT RNA levels in ovarian tumors.
Oncogene 25: 2636-45 (2006)
PM ID: 16532039 PMC1449872 NIHMS6123
489: Vallböhmer D, Brabender J, Yang DY, Danenberg K, Schneider PM, Metzger R, Holscher AH, Danenberg PV
Sex differences in the predictive power of the molecular prognostic factor HER2/neu in patients with non-small-cell lung cancer.
Clin Lung Cancer 7: 332-7 (2006)
PM ID: 16640805
490: Park DJ, Lenz HJ
Determinants of chemosensitivity in gastric cancer.
Curr Opin Pharmacol 6: 337-44 (2006)
PM ID: 16777480
491: Aiello F, Brizzi A, De Grazia O, Garofalo A, Grande F, Sinicropi MS, Dayam R, Neamati N
An approach to the stereo-controlled synthesis of polycyclic derivatives of l-4-thiazolidinecarboxylic acid active against HIV-1 integrase.
Eur J Med Chem 41: 914-7 (2006)
PM ID: 16781021
492: Al-Mawsawi LQ, Fikkert V, Dayam R, Witvrouw M, Burke TR, Borchers CH, Neamati N
Discovery of a small-molecule HIV-1 integrase inhibitor-binding site.
Proc Natl Acad Sci U S A 103: 10080-5 (2006)
PM ID: 16785440 PMC1502509
493: Pullmann R, Abdelmohsen K, Lal A, Martindale JL, Ladner RD, Gorospe M
Differential stability of thymidylate synthase 3'-untranslated region polymorphic variants regulated by AUF1.
J Biol Chem 281: 23456-63 (2006)
PM ID: 16787927
494: Ji C, Kaplowitz N
ER stress: can the liver cope?
J Hepatol 45: 321-33 (2006)
PM ID: 16797772
495: Weisenberger DJ, Siegmund KD, Campan M, Young JP, Long TI, Faasse MA, Kang GH, Widschwendter M, Weener D, Buchanan D, Koh H, Simms L, Barker MA, Leggett BA, Levine J, Kim MH, French AJ, Thibodeau SN, Jass J, Haile R, Laird PW
CpG island methylator phenotype underlies sporadic microsatellite instability and is tightly associated with BRAF mutation in colorectal cancer.
Nat Genet 38: 787-93 (2006)
PM ID: 16804544
496: Ji C, Chan CK, Kaplowitz N
Predominant role of sterol response element binding proteins (SREBP) lipogenic pathways in hepatic steatosis in the murine intragastric ethanol feeding model.
J Hepatol 45: 717-24 (2006)
PM ID: 16879892
497: Artinyan A, Essani R, Lake J, Kaiser AM, Vukasin P, Danenberg P, Danenberg K, Haile R, Beart RW
Molecular predictors of lymph node metastasis in colon cancer: increased risk with decreased thymidylate synthase expression.
J Gastrointest Surg 9: 1216-21; discussion 1221 (2006)
PM ID: 16332476
498: Siegmund KD, Levine AJ, Chang JL, Laird PW
Modeling exposures for DNA methylation profiles.
Cancer Epidemiol Biomarkers Prev 15: 567-72 (2006)
PM ID: 16537717
499: Kuramochi H, Hayashi K, Uchida K, Miyakura S, Shimizu D, Vallbohmer D, Park SY, Danenberg KD, Takasaki K, Danenberg PV
5-fluorouracil-related gene expression levels in primary colorectal cancer and corresponding liver metastasis.
Int J Cancer 119: 522-6 (2006)
PM ID: 16572420
500: Dziadziuszko R, Witta SE, Cappuzzo F, Park SY, Tanaka K, Danenberg PV, Barón AE, Crino L, Franklin WA, Bunn PA, Varella-Garcia M, Danenberg KD, Hirsch FR
Epidermal growth factor receptor messenger RNA expression, gene dosage, and gefitinib sensitivity in non-small cell lung cancer.
Clin Cancer Res 12: 3078-84 (2006)
PM ID: 16707605
501: Liu ZX, Han D, Gunawan BK, Kaplowitz N
Neutrophil depletion protects against murine acetaminophen hepatotoxicity.
Hepatology 43: 1220-30 (2006)
PM ID: 16729305
502: Watkins PB, Kaplowitz N, Slattery JT, Colonese CR, Colucci SV, Stewart PW, Harris SC
Aminotransferase elevations in healthy adults receiving 4 grams of acetaminophen daily: a randomized controlled trial.
JAMA 296: 87-93 (2006)
PM ID: 16820551
503: Marjoram P, Chang JL, Laird PW, Siegmund KD
Cluster analysis for DNA methylation profiles having a detection threshold.
BMC Bioinformatics 7: 361 (2006)
PM ID: 16872497 PMC1555616
504: Shimizu D, Vallböhmer D, Kuramochi H, Uchida K, Schneider S, Chandrasoma PT, Shimada H, DeMeester TR, Danenberg KD, Peters JH, DeMeester SR, Danenberg PV
Increasing cyclooxygenase-2 (cox-2) gene expression in the progression of Barrett's esophagus to adenocarcinoma correlates with that of Bcl-2.
Int J Cancer 119: 765-70 (2006)
PM ID: 16550596
505: Kaplowitz N
Rules and laws of drug hepatotoxicity.
Pharmacoepidemiol Drug Saf 15: 231-3 (2006)
PM ID: 16552791
506: Vallböhmer D, Lenz HJ
[Predictive and prognostic factors in the neoadjuvant/adjuvant therapy of gastrointestinal tumors: wishful thinking or reality?]
Zentralbl Chir 131: 148-56 (2006)
PM ID: 16612782
507: Ogino S, Kawasaki T, Brahmandam M, Cantor M, Kirkner GJ, Spiegelman D, Makrigiorgos GM, Weisenberger DJ, Laird PW, Loda M, Fuchs CS
Precision and performance characteristics of bisulfite conversion and real-time PCR (MethyLight) for quantitative DNA methylation analysis.
J Mol Diagn 8: 209-17 (2006)
PM ID: 16645207 PMC1867588
508: Pinski J, Wang QS, Quek ML, Cole A, Cooc J, Danenberg K, Danenberg PV
Genistein-induced neuroendocrine differentiation of prostate cancer cells.
Prostate 66: 1136-43 (2006)
PM ID: 16652383
509: Islam T, Gauderman WJ, Cozen W, Hamilton AS, Burnett ME, Mack TM
Differential twin concordance for multiple sclerosis by latitude of birthplace.
Ann Neurol 60: 56-64 (2006)
PM ID: 16685699
510: Gunawan BK, Liu ZX, Han D, Hanawa N, Gaarde WA, Kaplowitz N
c-Jun N-terminal kinase plays a major role in murine acetaminophen hepatotoxicity.
Gastroenterology 131: 165-78 (2006)
PM ID: 16831600
511: Li HY, Zawahir Z, Song LD, Long YQ, Neamati N
Sequence-based design and discovery of peptide inhibitors of HIV-1 integrase: insight into the binding mode of the enzyme.
J Med Chem 49: 4477-86 (2006)
PM ID: 16854053
512: Dayam R, Aiello F, Deng J, Wu Y, Garofalo A, Chen X, Neamati N
Discovery of small molecule integrin alphavbeta3 antagonists as novel anticancer agents.
J Med Chem 49: 4526-34 (2006)
PM ID: 16854058
513: Liu ZX, Kaplowitz N
Role of innate immunity in acetaminophen-induced hepatotoxicity.
Expert Opin Drug Metab Toxicol 2: 493-503 (2006)
PM ID: 16859400
514: Vallböhmer D, DeMeester SR, Oh DS, Banki F, Kuramochi H, Shimizu D, Hagen JA, Danenberg KD, Danenberg PV, Chandrasoma PT, Peters JH, DeMeester TR
Antireflux surgery normalizes cyclooxygenase-2 expression in squamous epithelium of the distal esophagus.
Am J Gastroenterol 101: 1458-66 (2006)
PM ID: 16863546
515: Zawahir Z, Neamati N
Inhibition of HIV-1 integrase activity by synthetic peptides derived from the HIV-1 HXB2 Pol region of the viral genome.
Bioorg Med Chem Lett 16: 5199-202 (2006)
PM ID: 16879966
516: Brzozowski Z, Saczewski F, Neamati N
Synthesis and anti-HIV-1 activity of a novel series of 1,4,2-benzodithiazine-dioxides.
Bioorg Med Chem Lett 16: 5298-302 (2006)
PM ID: 16908143
517: Choi J, Forman HJ, Ou JH, Lai MM, Seronello S, Nandipati A
Redox modulation of the hepatitis C virus replication complex is calcium dependent.
Free Radic Biol Med 41: 1488-98 (2006)
PM ID: 17023276
518: Ajani JA, Safran H, Bokemeyer C, Shah MA, Lenz HJ, Van Cutsem E, Burris HA, Lebwohl D, Mullaney B
A multi-center phase II study of BMS-247550 (Ixabepilone) by two schedules in patients with metastatic gastric adenocarcinoma previously treated with a taxane.
Invest New Drugs 24: 441-6 (2006)
PM ID: 16586011
519: Zhang W, Gordon M, Press OA, Rhodes K, Vallböhmer D, Yang DY, Park DJ, Fazzone W, Schultheis A, Sherrod AE, Iqbal S, Groshen S, Lenz HJ
Cyclin D1 and epidermal growth factor polymorphisms associated with survival in patients with advanced colorectal cancer treated with Cetuximab.
Pharmacogenet Genomics 16: 475-83 (2006)
PM ID: 16788380
520: Sechi M, Bacchi A, Carcelli M, Compari C, Duce E, Fisicaro E, Rogolino D, Gates P, Derudas M, Al-Mawsawi LQ, Neamati N
From ligand to complexes: inhibition of human immunodeficiency virus type 1 integrase by beta-diketo acid metal complexes.
J Med Chem 49: 4248-60 (2006)
PM ID: 16821784
521: Robinette D, Neamati N, Tomer KB, Borchers CH
Photoaffinity labeling combined with mass spectrometric approaches as a tool for structural proteomics.
Expert Rev Proteomics 3: 399-408 (2006)
PM ID: 16901199 PMC2266983 NIHMS13267
522: Tatalovich Z, Wilson JP, Mack TM, Yan Y, Cockburn MG
The objective assessment of lifetime cumulative ultraviolet exposure for determining melanoma risk.
J Photochem Photobiol B 85: 198-204 (2006)
PM ID: 16963272
523: Ceppi P, Volante M, Novello S, Rapa I, Danenberg KD, Danenberg PV, Cambieri A, Selvaggi G, Saviozzi S, Calogero R, Papotti M, Scagliotti GV
ERCC1 and RRM1 gene expressions but not EGFR are predictive of shorter survival in advanced non-small-cell lung cancer treated with cisplatin and gemcitabine.
Ann Oncol 17: 1818-25 (2006)
PM ID: 16980606
524: Lenz HJ
Anti-EGFR mechanism of action: antitumor effect and underlying cause of adverse events.
Oncology (Williston Park) 20: 5-13 (2006)
PM ID: 16736978
525: Schneider S, Park DJ, Yang D, El-Khoueiry AB, Sherrod AE, Groshen S, Streeter O, Iqbal S, Danenberg KD, Lenz HJ
Gene expression in tumor-adjacent normal tissue is associated with recurrence in patients with rectal cancer treated with adjuvant chemoradiation.
Pharmacogenet Genomics 16: 555-63 (2006)
PM ID: 16847424
526: Ogino S, Odze RD, Kawasaki T, Brahmandam M, Kirkner GJ, Laird PW, Loda M, Fuchs CS
Correlation of pathologic features with CpG island methylator phenotype (CIMP) by quantitative DNA methylation analysis in colorectal carcinoma.
Am J Surg Pathol 30: 1175-83 (2006)
PM ID: 16931963
527: Haile RW, Thomas DC, McGuire V, Felberg A, John EM, Milne RL, Hopper JL, Jenkins MA, Levine AJ, Daly MM, Buys SS, Senie RT, Andrulis IL, Knight JA, Godwin AK, Southey M, McCredie MR, Giles GG, Andrews L, Tucker K, Miron A, Apicella C, Tesoriero A, Bane A, Pike MC, kConFab Investigators , Ontario Cancer Genetics Network Investigators , Whittemore AS
BRCA1 and BRCA2 mutation carriers, oral contraceptive use, and breast cancer before age 50.
Cancer Epidemiol Biomarkers Prev 15: 1863-70 (2006)
PM ID: 17021353
528: Barry EL, Baron JA, Bhat S, Grau MV, Burke CA, Sandler RS, Ahnen DJ, Haile RW, O'Brien TG
Ornithine decarboxylase polymorphism modification of response to aspirin treatment for colorectal adenoma prevention.
J Natl Cancer Inst 98: 1494-500 (2006)
PM ID: 17047198
529: Garcia AA, Blessing JA, Darcy KM, Lenz HJ, Zhang W, Hannigan E, Moore DH
Phase II clinical trial of capecitabine in the treatment of advanced, persistent or recurrent squamous cell carcinoma of the cervix with translational research: a gynecologic oncology group study.
Gynecol Oncol 104: 572-9 (2006)
PM ID: 17049588 PMC1858667 NIHMS19454
530: Shibata SI, Chow WA, Frankel P, Juhasz A, Leong LA, Lim D, Margolin K, Morgan RJ, Newman EM, Somlo G, Yen Y, Synold TW, Gandara D, Lenz HJ, Doroshow JH
A phase I study of oxaliplatin in combination with gemcitabine: correlation of clinical outcome with gene expression.
Cancer Chemother Pharmacol 59: 549-57 (2006)
PM ID: 17051371
531: Meadows DC, Sanchez TW, Neamati N, North TW, Gervay-Hague J
Ring substituent effects on biological activity of vinyl sulfones as inhibitors of HIV-1.
Bioorg Med Chem 15: 1127-37 (2006)
PM ID: 17074494 PMC1994090 NIHMS15547
532: Grande F, Aiello F, Grazia OD, Brizzi A, Garofalo A, Neamati N
Synthesis and antitumor activities of a series of novel quinoxalinhydrazides.
Bioorg Med Chem 15: 288-94 (2006)
PM ID: 17085054
533: Hamilton AS, Lessov-Schlaggar CN, Cockburn MG, Unger JB, Cozen W, Mack TM
Gender differences in determinants of smoking initiation and persistence in California twins.
Cancer Epidemiol Biomarkers Prev 15: 1189-97 (2006)
PM ID: 16775180
534: Vallböhmer D, Iqbal S, Yang DY, Rhodes KE, Zhang W, Gordon M, Fazzone W, Schultheis AM, Sherrod AE, Danenberg KD, Lenz HJ
Molecular determinants of irinotecan efficacy.
Int J Cancer 119: 2435-42 (2006)
PM ID: 16894565
535: Azuma M, Danenberg KD, Iqbal S, El-Khoueiry AB, Zhang W, Yang D, Koizumi W, Saigenji K, Danenberg PV, Lenz HJ
Epidermal growth factor receptor and epidermal growth factor receptor variant III gene expression in metastatic colorectal cancer.
Clin Colorectal Cancer 6: 214-8 (2006)
PM ID: 17026791
536: Lenz HJ, Van Cutsem E, Khambata-Ford S, Mayer RJ, Gold P, Stella P, Mirtsching B, Cohn AL, Pippas AW, Azarnia N, Tsuchihashi Z, Mauro DJ, Rowinsky EK
Multicenter phase II and translational study of cetuximab in metastatic colorectal carcinoma refractory to irinotecan, oxaliplatin, and fluoropyrimidines.
J Clin Oncol 24: 4914-21 (2006)
PM ID: 17050875
537: Patil S, Kamath S, Sanchez TW, Neamati N, Schinazi RF, Buolamwini JK
Synthesis and biological evaluation of novel 5(H)-phenanthridin-6-ones, 5(H)-phenanthridin-6-one diketo acid, and polycyclic aromatic diketo acid analogs as new HIV-1 integrase inhibitors.
Bioorg Med Chem 15: 1212-28 (2006)
PM ID: 17158051
538: Dayam R, Deng J, Neamati N
HIV-1 integrase inhibitors: 2003-2004 update.
Med Res Rev 26: 271-309 (2006)
PM ID: 16496343
539: Vallböhmer D, DeMeester SR, Peters JH, Oh DS, Kuramochi H, Shimizu D, Hagen JA, Danenberg KD, Danenberg PV, DeMeester TR, Chandrasoma PT
Cdx-2 expression in squamous and metaplastic columnar epithelia of the esophagus.
Dis Esophagus 19: 260-6 (2006)
PM ID: 16866857
540: Vallböhmer D, Brabender J, Yang D, Schneider PM, Metzger R, Danenberg KD, Hölscher AH, Danenberg PV
DNA methyltransferases messenger RNA expression and aberrant methylation of CpG islands in non-small-cell lung cancer: association and prognostic value.
Clin Lung Cancer 8: 39-44 (2006)
PM ID: 16870044
541: McGuire V, John EM, Felberg A, Haile RW, Boyd NF, Thomas DC, Jenkins MA, Milne RL, Daly MB, Ward J, Terry MB, Andrulis IL, Knight JA, Godwin AK, Giles GG, Southey M, West DW, Hopper JL, Whittemore AS, kConFab Investigators
No increased risk of breast cancer associated with alcohol consumption among carriers of BRCA1 and BRCA2 mutations ages <50 years.
Cancer Epidemiol Biomarkers Prev 15: 1565-7 (2006)
PM ID: 16896052
542: Steinberg ML, Fremont A, Khan DC, Huang D, Knapp H, Karaman D, Forge N, Andre K, Chaiken LM, Streeter OE
Lay patient navigator program implementation for equal access to cancer care and clinical trials: essential steps and initial challenges.
Cancer 107: 2669-77 (2006)
PM ID: 17078056
543: Chen L, Xiong S, She H, Lin SW, Wang JG, Tsukamoto H
Iron causes interactions of TAK1, p21ras, and phosphatidylinositol 3-kinase in caveolae to activate IkappaB kinase in hepatic macrophages.
J Biol Chem 282: 5582-8 (2006)
PM ID: 17172471
544: Widschwendter M, Fiegl H, Egle D, Mueller-Holzner E, Spizzo G, Marth C, Weisenberger DJ, Campan M, Young JP, Jacobs I, Laird PW
Epigenetic stem cell signature in cancer.
Nat Genet 39: 157-8 (2006)
PM ID: 17200673
545: Iagaru A, Masamed R, Singer PA, Conti PS
2-Deoxy-2-[18F]fluoro-D-glucose-positron emission tomography and positron emission tomography/computed tomography diagnosis of patients with recurrent papillary thyroid cancer.
Mol Imaging Biol 8: 309-14 (2007)
PM ID: 16758370
546: Iagaru A, Chawla S, Menendez L, Conti PS
18F-FDG PET and PET/CT for detection of pulmonary metastases from musculoskeletal sarcomas.
Nucl Med Commun 27: 795-802 (2007)
PM ID: 16969262
547: Rongey C, Kaplowitz N
Current concepts and controversies in the treatment of alcoholic hepatitis.
World J Gastroenterol 12: 6909-21 (2007)
PM ID: 17109510
548: Andrade RJ, Lucena MI, Kaplowitz N, García-Muņoz B, Borraz Y, Pachkoria K, García-Cortés M, Fernández MC, Pelaez G, Rodrigo L, Durán JA, Costa J, Planas R, Barriocanal A, Guarner C, Romero-Gomez M, Muņoz-Yagüe T, Salmerón J, Hidalgo R
Outcome of acute idiosyncratic drug-induced liver injury: Long-term follow-up in a hepatotoxicity registry.
Hepatology 44: 1581-8 (2007)
PM ID: 17133470
549: Zheng YT, Chen WL, Louie SG, Yen TS, Ou JH
Hepatitis B virus promotes hepatocarcinogenesis in transgenic mice.
Hepatology 45: 16-21 (2007)
PM ID: 17187428
550: Wong HL, Byun HM, Kwan JM, Campan M, Ingles SA, Laird PW, Yang AS
Rapid and quantitative method of allele-specific DNA methylation analysis.
Biotechniques 41: 734-9 (2007)
PM ID: 17191619
551: Alauddin MM, Shahinian A, Park R, Tohme M, Fissekis JD, Conti PS
In vivo evaluation of 2'-deoxy-2'-[(18)F]fluoro-5-iodo-1-beta-D-arabinofuranosyluracil ([18F]FIAU) and 2'-deoxy-2'-[18F]fluoro-5-ethyl-1-beta-D-arabinofuranosyluracil ([18F]FEAU) as markers for suicide gene expression.
Eur J Nucl Med Mol Imaging 34: 822-9 (2007)
PM ID: 17206416
552: Kohonen-Corish MR, Sigglekow ND, Susanto J, Chapuis PH, Bokey EL, Dent OF, Chan CK, Lin BP, Seng TJ, Laird PW, Young JP, Leggett BA, Jass JR, Sutherland RL
Promoter methylation of the mutated in colorectal cancer gene is a frequent early event in colorectal cancer.
Oncogene 26: 4435-41 (2007)
PM ID: 17260021
553: Vallböhmer D, Kuramochi H, Shimizu D, Danenberg KD, Lindebjerg J, Nielsen JN, Jakobsen A, Danenberg PV
Molecular factors of 5-fluorouracil metabolism in colorectal cancer: analysis of primary tumor and lymph node metastasis.
Int J Oncol 28: 527-33 (2007)
PM ID: 16391809
554: Kim SY, Baron JA, Mott LA, Burke CA, Church TR, McKeown-Eyssen GE, Cole BF, Haile RW, Sandler RS
Aspirin may be more effective in preventing colorectal adenomas in patients with higher BMI (United States).
Cancer Causes Control 17: 1299-304 (2007)
PM ID: 17111262
555: Lenz HJ, Lee FC, Haller DG, Singh D, Benson AB, Strumberg D, Yanagihara R, Yao JC, Phan AT, Ajani JA
Extended safety and efficacy data on S-1 plus cisplatin in patients with untreated, advanced gastric carcinoma in a multicenter phase II study.
Cancer 109: 33-40 (2007)
PM ID: 17133415
556: Grau MV, Baron JA, Sandler RS, Wallace K, Haile RW, Church TR, Beck GJ, Summers RW, Barry EL, Cole BF, Snover DC, Rothstein RI, Mandel JS
Prolonged effect of calcium supplementation on risk of colorectal adenomas in a randomized trial.
J Natl Cancer Inst 99: 129-36 (2007)
PM ID: 17227996
557: Yang D, Schneider S, Azuma M, Iqbal S, El-Khoueiry AB, Groshen S, Agafitei D, Danenberg KD, Danenberg PV, Ladner RD, Lenz HJ
Gene expression levels of epidermal growth factor receptor, survivin, and vascular endothelial growth factor as molecular markers of lymph node involvement in patients with locally advanced rectal cancer.
Clin Colorectal Cancer 6: 305-11 (2007)
PM ID: 17241515
558: Han YP, Yan C, Zhou L, Qin L, Tsukamoto H
A matrix metalloproteinase-9 activation cascade by hepatic stellate cells in trans-differentiation in the three-dimensional extracellular matrix.
J Biol Chem 282: 12928-39 (2007)
PM ID: 17322299 PMC2376818 NIHMS46528
559: Al-Mawsawi LQ, Sechi M, Neamati N
Single amino acid substitution in HIV-1 integrase catalytic core causes a dramatic shift in inhibitor selectivity.
FEBS Lett 581: 1151-6 (2007)
PM ID: 17328897
560: Zheng YT, Chen WL, Ma WL, Chang CC, Ou JH
Enhancement of gene transactivation activity of androgen receptor by hepatitis B virus X protein.
Virology 363: 454-61 (2007)
PM ID: 17335866 PMC1976269 NIHMS25245
561: Alauddin MM, Shahinian A, Park R, Tohme M, Fissekis JD, Conti PS
Biodistribution and PET imaging of [(18)F]-fluoroadenosine derivatives.
Nucl Med Biol 34: 267-72 (2007)
PM ID: 17383576 PMC1905838 NIHMS21243
562: Whitehead RP, McCoy S, Macdonald JS, Rivkin SE, Neubauer MA, Dakhil SR, Lenz HJ, Tanaka MS, Abbruzzese JL, Southwest Oncology Group
Phase II trial of R115777 (NSC #70818) in patients with advanced colorectal cancer: a Southwest Oncology Group study.
Invest New Drugs 24: 335-41 (2007)
PM ID: 16683076
563: Goldberg RM, Rothenberg ML, Van Cutsem E, Benson AB, Blanke CD, Diasio RB, Grothey A, Lenz HJ, Meropol NJ, Ramanathan RK, Becerra CH, Wickham R, Armstrong D, Viele C
The continuum of care: a paradigm for the management of metastatic colorectal cancer.
Oncologist 12: 38-50 (2007)
PM ID: 17227899
564: Cockburn MG, Hamilton AS, Zadnick J, Cozen W, Mack TM
Twins as willing research participants: successes from studies nested within the California Twin Program.
Twin Res Hum Genet 9: 927-32 (2007)
PM ID: 17254432
565: Deng J, Dayam R, Al-Mawsawi LQ, Neamati N
Design of second generation HIV-1 integrase inhibitors.
Curr Pharm Des 13: 129-41 (2007)
PM ID: 17269923
566: Deng J, Grande F, Neamati N
Small molecule inhibitors of Stat3 signaling pathway.
Curr Cancer Drug Targets 7: 91-107 (2007)
PM ID: 17305481
567: Stern MC, Siegmund KD, Conti DV, Corral R, Haile RW
XRCC1, XRCC3, and XPD polymorphisms as modifiers of the effect of smoking and alcohol on colorectal adenoma risk.
Cancer Epidemiol Biomarkers Prev 15: 2384-90 (2007)
PM ID: 17164360
568: Cockburn MG, Hamilton A, Mack TM
The simultaneous assessment of constitutional, behavioral, and environmental factors in the development of large nevi.
Cancer Epidemiol Biomarkers Prev 16: 200-6 (2007)
PM ID: 17267390
569: Iagaru A, Masamed R, Keesara S, Conti PS
Breast MRI and 18F FDG PET/CT in the management of breast cancer.
Ann Nucl Med 21: 33-8 (2007)
PM ID: 17373334
570: Wu AH, Yu MC, Tseng CC, Stanczyk FZ, Pike MC
Diabetes and risk of breast cancer in Asian-American women.
Carcinogenesis 28: 1561-6 (2007)
PM ID: 17440036
571: Deng J, Sanchez TW, Al-Mawsawi LQ, Dayam R, Yunes RA, Garofalo A, Bolger MB, Neamati N
Discovery of structurally diverse HIV-1 integrase inhibitors based on a chalcone pharmacophore.
Bioorg Med Chem 15: 4985-5002 (2007)
PM ID: 17502148
572: Jenkins MA, Hayashi S, O'Shea AM, Burgart LJ, Smyrk TC, Shimizu D, Waring PM, Ruszkiewicz AR, Pollett AF, Redston M, Barker MA, Baron JA, Casey GR, Dowty JG, Giles GG, Limburg P, Newcomb P, Young JP, Walsh MD, Thibodeau SN, Lindor NM, LeMarchand L, Gallinger S, Haile RW, Potter JD, Hopper JL, Jass JR, Colon Cancer Family Registry
Pathology features in Bethesda guidelines predict colorectal cancer microsatellite instability: a population-based study.
Gastroenterology 133: 48-56 (2007)
PM ID: 17631130
573: Chen HM, Xia M, Lin MW, Yang HT, Kuhlenkamp JF, Li T, Sodir NM, Chen YH, Josef-Lenz H, Laird PW, Clarke S, Mato JM, Lu SC
Role of methionine adenosyltransferase 2A and S-adenosylmethionine in mitogen-induced growth of human colon cancer cells.
Gastroenterology 133: 207-18 (2007)
PM ID: 17631143
574: Tsukamoto H, She H, Hazra S, Cheng JP, Miyahara T
Anti-adipogenic regulation underlies hepatic stellate cell transdifferentiation.
J Gastroenterol Hepatol 21 Suppl 3: S102-5 (2007)
PM ID: 16958658
575: Pandol SJ, Tsukamoto H
Action plan for enhancing global collaboration on alcoholic liver and pancreatic diseases: white paper.
J Gastroenterol Hepatol 21 Suppl 3: S109-10 (2007)
PM ID: 16958661
576: Kaplowitz N, Ji C
Unfolding new mechanisms of alcoholic liver disease in the endoplasmic reticulum.
J Gastroenterol Hepatol 21 Suppl 3: S7-9 (2007)
PM ID: 16958678
577: Wu AH, Yu MC, Tseng CC, Pike MC
Body size, hormone therapy and risk of breast cancer in Asian-American women.
Int J Cancer 120: 844-52 (2007)
PM ID: 17131315
578: Iagaru A, Masamed R, Singer PA, Conti PS
Detection of occult medullary thyroid cancer recurrence with 2-deoxy-2-[F-18]fluoro-D-glucose-PET and PET/CT.
Mol Imaging Biol 9: 72-7 (2007)
PM ID: 17186139
579: Kerr KM, Galler JS, Hagen JA, Laird PW, Laird-Offringa IA
The role of DNA methylation in the development and progression of lung adenocarcinoma.
Dis Markers 23: 5-30 (2007)
PM ID: 17325423
580: Jadvar H, Henderson RW, Conti PS
[F-18]fluorodeoxyglucose positron emission tomography and positron emission tomography: computed tomography in recurrent and metastatic cholangiocarcinoma.
J Comput Assist Tomogr 31: 223-8 (2007)
PM ID: 17414758
581: Wu AH, Pike MC, Williams LD, Spicer D, Tseng CC, Churchwell MI, Doerge DR
Tamoxifen, soy, and lifestyle factors in Asian American women with breast cancer.
J Clin Oncol 25: 3024-30 (2007)
PM ID: 17536081
582: Hashibe M, Morgenstern H, Cui Y, Tashkin DP, Zhang ZF, Cozen W, Mack TM, Greenland S
Marijuana use and the risk of lung and upper aerodigestive tract cancers: results of a population-based case-control study.
Cancer Epidemiol Biomarkers Prev 15: 1829-34 (2007)
PM ID: 17035389
583: Cole BF, Baron JA, Sandler RS, Haile RW, Ahnen DJ, Bresalier RS, McKeown-Eyssen GE, Summers RW, Rothstein RI, Burke CA, Snover DC, Church TR, Allen JI, Robertson DJ, Beck GJ, Bond JH, Byers T, Mandel JS, Mott LA, Pearson LH, Barry EL, Rees JR, Marcon N, Saibil F, Ueland PM, Greenberg ER, Polyp Prevention Study Group
Folic acid for the prevention of colorectal adenomas: a randomized clinical trial.
JAMA 297: 2351-9 (2007)
PM ID: 17551129
584: Wu AH, Tseng CC, Hankin JH, Bernstein L
Fiber intake and risk of adenocarcinomas of the esophagus and stomach.
Cancer Causes Control 18: 713-22 (2007)
PM ID: 17562192
585: Kuo HC, Chuang KS, Liu WS, Wu AH, Lalonde R
Analysis of organ motion effects on the effective fluences for liver IMRT.
Phys Med Biol 52: 4227-44 (2007)
PM ID: 17664605
586: Dayam R, Al-Mawsawi LQ, Neamati N
HIV-1 integrase inhibitors: an emerging clinical reality.
Drugs R D 8: 155-68 (2007)
PM ID: 17472411
587: Venook AP, Blanke CD, Niedzwiecki D, Lenz HJ, Taylor JR, Hollis DR, Sutherland S, Goldberg RM
Revisiting the Cancer and Leukemia Group B/Southwest Oncology Group 80405 Trial: a phase III trial of chemotherapy and biologic agents for patients with untreated advanced colorectal adenocarcinoma.
Clin Colorectal Cancer 6: 536-8 (2007)
PM ID: 17553204
588: Haiman CA, Le Marchand L, Yamamato J, Stram DO, Sheng X, Kolonel LN, Wu AH, Reich D, Henderson BE
A common genetic risk factor for colorectal and prostate cancer.
Nat Genet 39: 954-6 (2007)
PM ID: 17618282 PMC2391283 NIHMS50016
589: Tsou JA, Galler JS, Wali A, Ye W, Siegmund KD, Groshen S, Laird PW, Turla S, Koss MN, Pass HI, Laird-Offringa IA
DNA methylation profile of 28 potential marker loci in malignant mesothelioma.
Lung Cancer 58: 220-30 (2007)
PM ID: 17659810 PMC2752414 NIHMS33001
590: Chu MW, Siegmund KD, Eckstam CL, Kim JY, Yang AS, Kanel GC, Tavaré S, Shibata D
Lack of increases in methylation at three CpG-rich genomic loci in non-mitotic adult tissues during aging.
BMC Med Genet 8: 50 (2007)
PM ID: 17672908 PMC1950491
591: Plasencia C, Martínez-Balibrea E, Martinez-Cardús A, Quinn DI, Abad A, Neamati N
Expression analysis of genes involved in oxaliplatin response and development of oxaliplatin-resistant HT29 colon cancer cells.
Int J Oncol 29: 225-35 (2007)
PM ID: 16773204
592: Islam T, Gauderman WJ, Cozen W, Mack TM
Childhood sun exposure influences risk of multiple sclerosis in monozygotic twins.
Neurology 69: 381-8 (2007)
PM ID: 17646631
593: Lou H, Kaplowitz N
Glutathione depletion down-regulates tumor necrosis factor alpha-induced NF-kappaB activity via IkappaB kinase-dependent and -independent mechanisms.
J Biol Chem 282: 29470-81 (2007)
PM ID: 17690092
594: Wu AH, Chen J, Baserga R
Nuclear insulin receptor substrate-1 activates promoters of cell cycle progression genes.
Oncogene 27: 397-403 (2007)
PM ID: 17700539
595: Tsukamoto H
Conceptual importance of identifying alcoholic liver disease as a lifestyle disease.
J Gastroenterol 42: 603-9 (2007)
PM ID: 17701122
596: Astner S, Wu AH, Chen J, Philips N, Rius-Diaz F, Parrado C, Mihm MC, Goukassian DA, Pathak MA, González S
Dietary lutein/zeaxanthin partially reduces photoaging and photocarcinogenesis in chronically UVB-irradiated Skh-1 hairless mice.
Skin Pharmacol Physiol 20: 283-91 (2007)
PM ID: 17717424
597: Madlensky L, Daftary D, Burnett T, Harmon P, Jenkins MA, Maskiell J, Nigon S, Phillips K, Templeton AS, Limburg PJ, Haile RW, Potter JD, Gallinger S, Baron JA
Accuracy of colorectal polyp self-reports: findings from the colon cancer family registry.
Cancer Epidemiol Biomarkers Prev 16: 1898-901 (2007)
PM ID: 17726139
598: Mori R, Ishikawa T, Ichikawa Y, Taniguchi K, Matsuyama R, Ueda M, Fujii Y, Endo I, Togo S, Danenberg PV, Shimada H
Human equilibrative nucleoside transporter 1 is associated with the chemosensitivity of gemcitabine in human pancreatic adenocarcinoma and biliary tract carcinoma cells.
Oncol Rep 17: 1201-5 (2007)
PM ID: 17390066
599: Abboud G, Kaplowitz N
Drug-induced liver injury.
Drug Saf 30: 277-94 (2007)
PM ID: 17408305
600: Purohit V, Abdelmalek MF, Barve S, Benevenga NJ, Halsted CH, Kaplowitz N, Kharbanda KK, Liu QY, Lu SC, McClain CJ, Swanson C, Zakhari S
Role of S-adenosylmethionine, folate, and betaine in the treatment of alcoholic liver disease: summary of a symposium.
Am J Clin Nutr 86: 14-24 (2007)
PM ID: 17616758
601: Liao CP, Zhong C, Saribekyan G, Bading JR, Park R, Conti PS, Moats RA, Berns A, Shi W, Zhou Z, Nikitin AY, Roy-Burman P
Mouse models of prostate adenocarcinoma with the capacity to monitor spontaneous carcinogenesis by bioluminescence or fluorescence.
Cancer Res 67: 7525-33 (2007)
PM ID: 17671224
602: Zhang W, Gordon M, Schultheis AM, Yang DY, Nagashima F, Azuma M, Chang HM, Borucka E, Lurje G, Sherrod AE, Iqbal S, Groshen S, Lenz HJ
FCGR2A and FCGR3A polymorphisms associated with clinical outcome of epidermal growth factor receptor expressing metastatic colorectal cancer patients treated with single-agent cetuximab.
J Clin Oncol 25: 3712-8 (2007)
PM ID: 17704420
603: Zhang W, Press OA, Haiman CA, Yang DY, Gordon MA, Fazzone W, El-Khoueiry AB, Iqbal S, Sherrod AE, Lurje G, Lenz HJ
Association of methylenetetrahydrofolate reductase gene polymorphisms and sex-specific survival in patients with metastatic colon cancer.
J Clin Oncol 25: 3726-31 (2007)
PM ID: 17704422
604: Saltz LB, Lenz HJ, Kindler HL, Hochster HS, Wadler S, Hoff PM, Kemeny NE, Hollywood EM, Gonen M, Quinones M, Morse M, Chen HX
Randomized phase II trial of cetuximab, bevacizumab, and irinotecan compared with cetuximab and bevacizumab alone in irinotecan-refractory colorectal cancer: the BOND-2 study.
J Clin Oncol 25: 4557-61 (2007)
PM ID: 17876013
605: Siegmund KD, Connor CM, Campan M, Long TI, Weisenberger DJ, Biniszkiewicz D, Jaenisch R, Laird PW, Akbarian S
DNA methylation in the human cerebral cortex is dynamically regulated throughout the life span and involves differentiated neurons.
PLoS One 2: e895 (2007)
PM ID: 17878930 PMC1964879
606: Al-Mawsawi LQ, Neamati N
Blocking interactions between HIV-1 integrase and cellular cofactors: an emerging anti-retroviral strategy.
Trends Pharmacol Sci 28: 526-35 (2007)
PM ID: 17888520
607: Beumer JH, Parise RA, Newman EM, Doroshow JH, Synold TW, Lenz HJ, Egorin MJ
Concentrations of the DNA methyltransferase inhibitor 5-fluoro-2'-deoxycytidine (FdCyd) and its cytotoxic metabolites in plasma of patients treated with FdCyd and tetrahydrouridine (THU).
Cancer Chemother Pharmacol 62: 363-8 (2007)
PM ID: 17899082
608: Dayam R, Al-Mawsawi LQ, Neamati N
Substituted 2-pyrrolinone inhibitors of HIV-1 integrase.
Bioorg Med Chem Lett 17: 6155-9 (2007)
PM ID: 17911021
609: Brzozowski Z, Slawinski J, Saczewski F, Sanchez TW, Neamati N
Synthesis, anti-HIV-1 integrase, and cytotoxic activities of 4-chloro-N-(4-oxopyrimidin-2-yl)-2-mercaptobenzenesulfonamide derivatives.
Eur J Med Chem 43: 1188-98 (2007)
PM ID: 17949860
610: Vallböhmer D, Yang DY, Kuramochi H, Shimizu D, Danenberg KD, Lindebjerg J, Nielsen JN, Jakobsen A, Danenberg PV
DPD is a molecular determinant of capecitabine efficacy in colorectal cancer.
Int J Oncol 31: 413-8 (2007)
PM ID: 17611699
611: Deapen D, Cockburn MG, Pinder R, Lu SC, Wohl AR
Population-based linkage of AIDS and cancer registries: importance of linkage algorithm.
Am J Prev Med 33: 134-6 (2007)
PM ID: 17673101
612: Al-Mawsawi LQ, Dayam R, Taheri L, Witvrouw M, Debyser Z, Neamati N
Discovery of novel non-cytotoxic salicylhydrazide containing HIV-1 integrase inhibitors.
Bioorg Med Chem Lett 17: 6472-5 (2007)
PM ID: 17950601
613: Tsou JA, Galler JS, Siegmund KD, Laird PW, Turla S, Cozen W, Hagen JA, Koss MN, Laird-Offringa IA
Identification of a panel of sensitive and specific DNA methylation markers for lung adenocarcinoma.
Mol Cancer 6: 70 (2007)
PM ID: 17967182 PMC2206053
614: Sodir NM, Chen X, Park R, Nickel AE, Conti PS, Moats RA, Bading JR, Shibata D, Laird PW
Smad3 deficiency promotes tumorigenesis in the distal colon of ApcMin/+ mice.
Cancer Res 66: 8430-8 (2007)
PM ID: 16951153
615: Chen T, Burke KA, Zhan Y, Wang XD, Shibata D, Zhao Y
IL-12 facilitates both the recovery of endogenous hematopoiesis and the engraftment of stem cells after ionizing radiation.
Exp Hematol 35: 203-13 (2007)
PM ID: 17258069
616: Largent JA, Capanu M, Bernstein L, Langholz B, Mellemkaer L, Malone KE, Begg CB, Haile RW, Lynch CF, Anton-Culver H, Wolitzer A, Bernstein JL
Reproductive history and risk of second primary breast cancer: the WECARE study.
Cancer Epidemiol Biomarkers Prev 16: 906-11 (2007)
PM ID: 17507614
617: Lenz HJ
Management and preparedness for infusion and hypersensitivity reactions.
Oncologist 12: 601-9 (2007)
PM ID: 17522249
618: Berg T, Rountree CB, Lee L, Estrada J, Sala FG, Choe A, Veltmaat JM, De Langhe S, Lee RH, Tsukamoto H, Crooks GM, Bellusci S, Wang KS
Fibroblast growth factor 10 is critical for liver growth during embryogenesis and controls hepatoblast survival via beta-catenin activation.
Hepatology 46: 1187-97 (2007)
PM ID: 17668871
619: Gunawan BK, Kaplowitz N
Mechanisms of drug-induced liver disease.
Clin Liver Dis 11: 459-75, v (2007)
PM ID: 17723915
620: Castellani ML, Bhattacharya K, Tagen M, Kempuraj D, Perrella A, De Lutiis MA, Boucher W, Conti PS, Theoharides TC, Cerulli G, Salini V, Neri G
Anti-chemokine therapy for inflammatory diseases.
Int J Immunopathol Pharmacol 20: 447-53 (2007)
PM ID: 17880758
621: Falasca K, Ucciferri C, Manzoli L, Mancino P, Pizzigallo E, Conti PS, Vecchiet J
Metabolic syndrome and cardiovascular risk in HIV-infected patients with lipodystrophy.
Int J Immunopathol Pharmacol 20: 519-27 (2007)
PM ID: 17880765
622: Ley EJ, Kaiser AM, Vukasin P, Ault G, Etzioni DA, Beart RW
Questions about efficacy of continuous wound catheters.
J Am Coll Surg 205: e2-3; author reply e3 (2007)
PM ID: 17903715
623: Saltz LB, Rosen LS, Marshall JL, Belt RJ, Hurwitz HI, Eckhardt SG, Bergsland EK, Haller DG, Lockhart AC, Rocha Lima CM, Huang X, DePrimo SE, Chow-Maneval E, Chao RC, Lenz HJ
Phase II trial of sunitinib in patients with metastatic colorectal cancer after failure of standard therapy.
J Clin Oncol 25: 4793-9 (2007)
PM ID: 17947727
624: Newcomb PA, Baron JA, Cotterchio M, Gallinger S, Grove J, Haile R, Hall D, Hopper JL, Jass J, Le Marchand L, Limburg P, Lindor NM, Potter JD, Templeton AS, Thibodeau SN, Seminara D, Colon Cancer Family Registry
Colon Cancer Family Registry: an international resource for studies of the genetic epidemiology of colon cancer.
Cancer Epidemiol Biomarkers Prev 16: 2331-43 (2007)
PM ID: 17982118
625: Cheng JH, She H, Han YP, Wang JG, Xiong S, Asahina K, Tsukamoto H
Wnt antagonism inhibits hepatic stellate cell activation and liver fibrosis.
Am J Physiol Gastrointest Liver Physiol 294: G39-49 (2007)
PM ID: 18006602
626: Conti PS, Bading JR, Mouton PP, Links JM, Alauddin MM, Fissekis JD, Ravert HT, Hilton J, Wong DF, Anderson JH
In vivo measurement of cell proliferation in canine brain tumor using C-11-labeled FMAU and PET.
Nucl Med Biol 35: 131-41 (2007)
PM ID: 18158952
627: Rubio-Viqueira B, Jimeno A, Cusatis G, Zhang XK, Iacobuzio-Donahue C, Karikari C, Shi C, Danenberg K, Danenberg PV, Kuramochi H, Tanaka K, Singh S, Salimi-Moosavi H, Bouraoud N, Amador ML, Altiok S, Kulesza P, Yeo C, Messersmith W, Eshleman J, Hruban RH, Maitra A, Hidalgo M
An in vivo platform for translational drug development in pancreatic cancer.
Clin Cancer Res 12: 4652-61 (2007)
PM ID: 16899615
628: Vallböhmer D, Marjoram P, Kuramochi H, Shimizu D, Jung HS, DeMeester SR, Oh D, Chandrasoma PT, Danenberg KD, DeMeester TR, Danenberg PV, Peters JH
Towards the molecular characterization of disease: comparison of molecular and histological analysis of esophageal epithelia.
J Gastrointest Surg 11: 1095-104 (2007)
PM ID: 17623264
629: Ji C, Shinohara M, Kuhlenkamp JF, Chan CK, Kaplowitz N
Mechanisms of protection by the betaine-homocysteine methyltransferase/betaine system in HepG2 cells and primary mouse hepatocytes.
Hepatology 46: 1586-96 (2007)
PM ID: 17705221 PMC2642650 NIHMS88901
630: Haiman CA, Hsu CP, de Bakker PI, Frasco MA, Sheng X, Van Den Berg D, Casagrande JT, Kolonel LN, Le Marchand L, Hankinson SE, Han J, Dunning AM, Pooley KA, Freedman ML, Hunter DJ, Wu AH, Stram DO, Henderson BE
Comprehensive association testing of common genetic variation in DNA repair pathway genes in relationship with breast cancer risk in multiple populations.
Hum Mol Genet 17: 825-34 (2007)
PM ID: 18056155
631: Houshdaran S, Cortessis VK, Siegmund KD, Yang AJ, Laird PW, Sokol RZ
Widespread epigenetic abnormalities suggest a broad DNA methylation erasure defect in abnormal human sperm.
PLoS One 2: e1289 (2007)
PM ID: 18074014 PMC2100168
632: Cozen W, Gill PS, Salam MT, Nieters A, Masood R, Cockburn MG, Gauderman WJ, Martínez-Maza O, Nathwani BN, Pike MC, Van Den Berg DJ, Hamilton AS, Deapen DM, Mack TM
Interleukin-2, interleukin-12, and interferon-gamma levels and risk of young adult Hodgkin lymphoma.
Blood 111: 3377-82 (2007)
PM ID: 18077789 PMC2275007
633: Kang GH, Lee SY, Cho NY, Gandamihardja TA, Long TI, Weisenberger DJ, Campan M, Laird PW
DNA methylation profiles of gastric carcinoma characterized by quantitative DNA methylation analysis.
Lab Invest 88: 161-70 (2007)
PM ID: 18158559
634: Bertelsen L, Bernstein L, Olsen JH, Mellemkjær L, Haile RW, Lynch CF, Malone KE, Anton-Culver H, Christensen J, Langholz B, Thomas DC, Begg CB, Capanu M, Ejlertsen B, Stovall M, Boice JD, Shore RE, Women's Environment, Cancer and Radiation Epidemio , Bernstein JL
Effect of systemic adjuvant treatment on risk for contralateral breast cancer in the Women's Environment, Cancer and Radiation Epidemiology Study.
J Natl Cancer Inst 100: 32-40 (2007)
PM ID: 18159070
635: Hutchison GB, Rothman KJ, Cole PA, Mack TM, Weiss NS, Monson RR
Brian MacMahon, 1923-2007.
Epidemiology 19: 357 (2007)
PM ID: 18277172
636: Borugian MJ, Spinelli JJ, Sun Z, Kolonel LN, Oakley-Girvan I, Pollak MD, Whittemore AS, Wu AH, Gallagher RP
Prediagnostic C-peptide and risk of prostate cancer.
Cancer Epidemiol Biomarkers Prev 16: 2164-5 (2008)
PM ID: 17932367
637: Olsen CM, Green AC, Zens MS, Stukel TA, Bataille V, Berwick M, Elwood JM, Gallagher RP, Holly EA, Kirkpatrick CS, Mack TM, Østerlind A, Rosso S, Swerdlow AJ, Karagas MR
Anthropometric factors and risk of melanoma in women: a pooled analysis.
Int J Cancer 122: 1100-8 (2008)
PM ID: 17990316
638: Wiseman GA, Conti PS, Vo K, Schilder RJ, Gordon LI, Emmanouilides C, Silverman DH, Witzig TE, Darif M, Molina A
Weight-based dosing of Yttrium 90 ibritumomab tiuxetan in patients with relapsed or refractory B-cell non-Hodgkin lymphoma.
Clin Lymphoma Myeloma 7: 514-7 (2008)
PM ID: 18021468
639: Liu Z, Choi SW, Crott JW, Keyes MK, Jang H, Smith DE, Kim MH, Laird PW, Bronson R, Mason JB
Mild depletion of dietary folate combined with other B vitamins alters multiple components of the Wnt pathway in mouse colon.
J Nutr 137: 2701-8 (2008)
PM ID: 18029487
640: Poynter JN, Figueiredo JC, Conti DV, Kennedy K, Gallinger S, Siegmund KD, Casey GR, Thibodeau SN, Jenkins MA, Hopper JL, Byrnes GB, Baron JA, Goode EL, Tiirikainen M, Lindor NM, Grove J, Newcomb P, Jass J, Young JP, Potter JD, Haile RW, Duggan DJ, Le Marchand L, Colon CFR
Variants on 9p24 and 8q24 are associated with risk of colorectal cancer: results from the Colon Cancer Family Registry.
Cancer Res 67: 11128-32 (2008)
PM ID: 18056436
641: Garcia AA, Hirte H, Fleming GF, Yang D, Tsao-Wei DD, Roman LD, Groshen S, Swenson SD, Markland FS, Gandara D, Scudder S, Morgan RJ, Chen HM, Lenz HJ, Oza AM
Phase II clinical trial of bevacizumab and low-dose metronomic oral cyclophosphamide in recurrent ovarian cancer: a trial of the California, Chicago, and Princess Margaret Hospital phase II consortia.
J Clin Oncol 26: 76-82 (2008)
PM ID: 18165643
642: Davies AM, Ruel C, Lara PN, Lau DH, Gumerlock PH, Bold RJ, Shibata SI, Lenz HJ, Schenkein DP, Gandara DR
The proteasome inhibitor bortezomib in combination with gemcitabine and carboplatin in advanced non-small cell lung cancer: a California Cancer Consortium Phase I study.
J Thorac Oncol 3: 68-74 (2008)
PM ID: 18166843
643: Begg CB, Haile RW, Borg A, Malone KE, Concannon P, Thomas DC, Langholz B, Bernstein L, Olsen JH, Lynch CF, Anton-Culver H, Capanu M, Liang X, Hummer AJ, Sima C, Bernstein JL
Variation of breast cancer risk among BRCA1/2 carriers.
JAMA 299: 194-201 (2008)
PM ID: 18182601 PMC2714486 NIHMS130486
644: Wu AH, Yu MC, Tseng CC, Pike MC
Epidemiology of soy exposures and breast cancer risk.
Br J Cancer 98: 9-14 (2008)
PM ID: 18182974 PMC2359677
645: Duan L, Wu AH, Sullivan-Halley J, Bernstein L
Nonsteroidal anti-inflammatory drugs and risk of esophageal and gastric adenocarcinomas in Los Angeles County.
Cancer Epidemiol Biomarkers Prev 17: 126-34 (2008)
PM ID: 18187391
646: Banki F, Mason RJ, Hagen JA, DeMeester SR, Lipham JC, Danenberg K, Danenberg P, DeMeester TR
Plasma DNA: a molecular marker of surgical insult and postoperative recovery in esophageal cancer.
Eur Surg Res 40: 273-8 (2008)
PM ID: 18219202
647: Pearce CL, Wu AH, Gayther SA, Bale AE, Australian Cancer Study (Ovarian Cancer) and Austr , Beck PA, Beesley J, Chanock SJ, Cramer DW, DiCioccio RA, Edwards RD, Fredericksen ZS, Garcia-Closas M, Goode EL, Green AC, Hartmann LC, Hogdall E, Kjaer SK, Lissowska J, McGuire V, Modugno F, Moysich KB, Ness RB, Ramus SJ, Risch HA, Sellers TA, Song H, Stram DO, Terry KL, Webb PM, Whiteman DC, Whittemore AS, Zheng W, Pharoah PD, Chenevix-Trench G, Pike MC, Schildkraut J, Berchuck A, Ovarian Cancer Association Consortium
Progesterone receptor variation and risk of ovarian cancer is limited to the invasive endometrioid subtype: results from the Ovarian Cancer Association Consortium pooled analysis.
Br J Cancer 98: 282-8 (2008)
PM ID: 18219286 PMC2361465
648: Speranza L, De Lutiis MA, Shaik YB, Felaco M, Patruno A, Tetè S, Tetè A, Mastrangelo F, Madhappan B, Castellani ML, Conti F, Vecchiet J, Theoharides TC, Conti PS, Grilli A
Localization and activity of iNOS in normal human lung tissue and lung cancer tissue.
Int J Biol Markers 22: 226-31 (2008)
PM ID: 17922468
649: Dayam R, Gundla R, Al-Mawsawi LQ, Neamati N
HIV-1 integrase inhibitors: 2005-2006 update.
Med Res Rev 28: 118-54 (2008)
PM ID: 17979144
650: Shibata D
Stem cells as common ancestors in a colorectal cancer ancestral tree.
Curr Opin Gastroenterol 24: 59-63 (2008)
PM ID: 18043234
651: Lee YC, Morgenstern H, Greenland S, Tashkin DP, Papp J, Sinsheimer J, Cao W, Hashibe M, You NC, Mao JT, Cozen W, Mack TM, Zhang ZF
A case-control study of the association of the polymorphisms and haplotypes of DNA ligase I with lung and upper-aerodigestive-tract cancers.
Int J Cancer 122: 1630-8 (2008)
PM ID: 18059021 PMC2676936 NIHMS96130
652: Gibbons J, Egorin MJ, Ramanathan RK, Fu P, Mulkerin DL, Shibata SI, Takimoto CH, Mani S, LoRusso PA, Grem JL, Pavlick A, Lenz HJ, Flick SM, Reynolds S, Lagattuta TF, Parise RA, Wang Y, Murgo AJ, Ivy SP, Remick SC, National Cancer Institute Organ Dysfunction Workin
Phase I and pharmacokinetic study of imatinib mesylate in patients with advanced malignancies and varying degrees of renal dysfunction: a study by the National Cancer Institute Organ Dysfunction Working Group.
J Clin Oncol 26: 570-6 (2008)
PM ID: 18235116
653: Kobayashi H, Sugihara K, Uetake H, Higuchi T, Yasuno M, Enomoto M, Kuramochi H, Lenz HJ, Danenberg KD, Danenberg PV
Messenger RNA expression of vascular endothelial growth factor and its receptors in primary colorectal cancer and corresponding liver metastasis.
Ann Surg Oncol 15: 1232-8 (2008)
PM ID: 18239970
654: Shibata D
Mistakes make history: visualizing intestinal tectonics.
Gastroenterology 134: 628-31 (2008)
PM ID: 18242228
655: Figueiredo JC, Bernstein L, Capanu M, Malone KE, Lynch CF, Anton-Culver H, Stovall M, Bertelsen L, Haile RW, Bernstein JL, WECARE Study Group
Oral contraceptives, postmenopausal hormones, and risk of asynchronous bilateral breast cancer: the WECARE Study Group.
J Clin Oncol 26: 1411-8 (2008)
PM ID: 18250348
656: Mellemkjær L, Dahl C, Olsen JH, Bertelsen L, Guldberg P, Christensen J, Børresen-Dale AL, Stovall M, Langholz B, Bernstein L, Lynch CF, Malone KE, Haile RW, Andersson M, Thomas DC, Concannon P, Capanu M, Boice JD, WECARE Study Collaborative Group , Bernstein JL
Risk for contralateral breast cancer among carriers of the CHEK2*1100delC mutation in the WECARE Study.
Br J Cancer 98: 728-33 (2008)
PM ID: 18253122 PMC2259175
657: Ulaner GA, Colletti PM, Conti PS
B-cell non-Hodgkin lymphoma: PET/CT evaluation after 90Y-ibritumomab tiuxetan radioimmunotherapy--initial experience.
Radiology 246: 895-902 (2008)
PM ID: 18258810
658: Miller AJ, Dudley SD, Tsao JL, Shibata D, Liskay RM
Tractable Cre-lox system for stochastic alteration of genes in mice.
Nat Methods 5: 227-9 (2008)
PM ID: 18264106 PMC2394730 NIHMS49371
659: Dayam R, Al-Mawsawi LQ, Zawahir Z, Witvrouw M, Debyser Z, Neamati N
Quinolone 3-carboxylic acid pharmacophore: design of second generation HIV-1 integrase inhibitors.
J Med Chem 51: 1136-44 (2008)
PM ID: 18281931
660: Pike BL, Greiner TC, Wang XD, Weisenburger DD, Hsu YH, Renaud G, Wolfsberg TG, Kim MH, Weisenberger DJ, Siegmund KD, Ye W, Groshen S, Mehrian-Shai R, Delabie J, Chan WC, Laird PW, Hacia JG
DNA methylation profiles in diffuse large B-cell lymphoma and their relationship to gene expression status.
Leukemia 22: 1035-43 (2008)
PM ID: 18288132 PMC2654231 NIHMS97202
661: Jadvar H, Quan V, Henderson RW, Conti PS
[F-18]-Fluorodeoxyglucose PET and PET-CT in diagnostic imaging evaluation of locally recurrent and metastatic bladder transitional cell carcinoma.
Int J Clin Oncol 13: 42-7 (2008)
PM ID: 18307018 PMC2295284 NIHMS43945
662: Kuramochi H, Hayashi K, Uchida K, Nakajima G, Hatori T, Danenberg KD, Danenberg PV, Yamamoto M
High intratumoral dihydropyrimidine dehydrogenase mRNA levels in pancreatic cancer associated with a high rate of response to S-1.
Cancer Chemother Pharmacol 63: 85-9 (2008)
PM ID: 18309485
663: Iagaru A, Masamed R, Chawla SP, Menendez LR, Fedenko A, Conti PS
F-18 FDG PET and PET/CT evaluation of response to chemotherapy in bone and soft tissue sarcomas.
Clin Nucl Med 33: 8-13 (2008)
PM ID: 18097248
664: Kuramochi H, Tanaka K, Oh D, Lehman BJ, Dunst CM, Yang DY, De Meester SR, Hagen JA, Danenberg KD, De Meester TR, Danenberg PV
Thymidylate synthase polymorphisms and mRNA expression are independent chemotherapy predictive markers in esophageal adenocarcinoma patients.
Int J Oncol 32: 201-8 (2008)
PM ID: 18097560
665: Al-Mawsawi LQ, Christ F, Dayam R, Debyser Z, Neamati N
Inhibitory profile of a LEDGF/p75 peptide against HIV-1 integrase: insight into integrase-DNA complex formation and catalysis.
FEBS Lett 582: 1425-30 (2008)
PM ID: 18331842
666: Hanawa N, Shinohara M, Saberi B, Gaarde WA, Han D, Kaplowitz N
Role of JNK translocation to mitochondria leading to inhibition of mitochondria bioenergetics in acetaminophen-induced liver injury.
J Biol Chem 283: 13565-77 (2008)
PM ID: 18337250 PMC2376214
667: Cao Q, Li ZB, Chen KY, Wu Z, He L, Neamati N, Chen X
Evaluation of biodistribution and anti-tumor effect of a dimeric RGD peptide-paclitaxel conjugate in mice with breast cancer.
Eur J Nucl Med Mol Imaging 35: 1489-98 (2008)
PM ID: 18373091
668: Brzozowski Z, Saczewski F, Slawinski J, Sanchez TW, Neamati N
Synthesis and anti-HIV-1 integrase activities of 3-aroyl-2,3-dihydro-1,1-dioxo-1,4,2-benzodithiazines.
Eur J Med Chem 44: 190-6 (2008)
PM ID: 18394758
669: Yoo CB, Chuang JC, Byun HM, Egger G, Yang AS, Dubeau L, Long TI, Laird PW, Marquez VE, Jones PA
Long-term epigenetic therapy with oral zebularine has minimal side effects and prevents intestinal tumors in mice.
Cancer Prev Res (Phila Pa) 1: 233-40 (2008)
PM ID: 19138966
670: Lurje G, Zhang W, Lenz HJ
Molecular prognostic markers in locally advanced colon cancer.
Clin Colorectal Cancer 6: 683-90 (2008)
PM ID: 18039421
671: Lurje G, Zhang W, Yang D, Groshen S, Hendifar AE, Husain H, Nagashima F, Chang HM, Fazzone W, Ladner RD, Pohl A, Ning Y, Iqbal S, El-Khoueiry AB, Lenz HJ
Thymidylate synthase haplotype is associated with tumor recurrence in stage II and stage III colon cancer.
Pharmacogenet Genomics 18: 161-8 (2008)
PM ID: 18192902
672: Borugian MJ, Spinelli JJ, Sun Z, Kolonel LN, Oakley-Girvan I, Pollak MD, Whittemore AS, Wu AH, Gallagher RP
Prostate cancer risk in relation to insulin-like growth factor (IGF)-I and IGF-binding protein-3: a prospective multiethnic study.
Cancer Epidemiol Biomarkers Prev 17: 252-4 (2008)
PM ID: 18199733
673: Grande F, Garofalo A, Neamati N
Small molecules anti-HIV therapeutics targeting CXCR4.
Curr Pharm Des 14: 385-404 (2008)
PM ID: 18289065
674: Haiman CA, Garcia RR, Kolonel LN, Henderson BE, Wu AH, Le Marchand L
A promoter polymorphism in the CASP8 gene is not associated with cancer risk.
Nat Genet 40: 259-60; author reply 260-1 (2008)
PM ID: 18305469
675: Mori R, Wang QS, Quek ML, Tarabolous C, Cheung EM, Ye W, Groshen S, Hawes D, Togo S, Shimada H, Danenberg KD, Danenberg PV, Pinski JK
Prognostic value of the androgen receptor and its coactivators in patients with D1 prostate cancer.
Anticancer Res 28: 425-30 (2008)
PM ID: 18383880
676: Sobrero AF, Maurel J, Fehrenbacher L, Scheithauer W, Abubakr YA, Lutz MP, Vega-Villegas ME, Eng C, Steinhauer EU, Prausova J, Lenz HJ, Borg C, Middleton G, Kröning H, Luppi G, Kisker O, Zubel A, Langer C, Kopit J, Burris HA
EPIC: phase III trial of cetuximab plus irinotecan after fluoropyrimidine and oxaliplatin failure in patients with metastatic colorectal cancer.
J Clin Oncol 26: 2311-9 (2008)
PM ID: 18390971
677: Ma HC, Lin TW, Li HY, Iguchi-Ariga SM, Ariga H, Chuang YL, Ou JH, Lo SY
Hepatitis C virus ARFP/F protein interacts with cellular MM-1 protein and enhances the gene trans-activation activity of c-Myc.
J Biomed Sci 15: 417-25 (2008)
PM ID: 18398700
678: Chu MW, Siegmund KD, Hao QL, Crooks GM, Tavaré S, Shibata D
Inferring relative numbers of human leucocyte genome replications.
Br J Haematol 141: 862-71 (2008)
PM ID: 18410448
679: Theisen J, Danenberg K, Ott K, Becker K, Danenberg P, Stein HJ, Siewert JR
Predictors of response and survival for neoadjuvant treated patients with esophageal adenocarcinoma.
Dis Esophagus 21: 601-6 (2008)
PM ID: 18430179
680: Wu AH, Wang RH, Koh WP, Stanczyk FZ, Lee HP, Yu MC
Sleep duration, melatonin and breast cancer among Chinese women in Singapore.
Carcinogenesis 29: 1244-8 (2008)
PM ID: 18448486 PMC2574570 NIHMS54502
681: Banki F, Yacoub WN, Hagen JA, Mason RJ, Ayazi S, DeMeester SR, Lipham JC, Danenberg K, Danenberg P, DeMeester TR
Plasma DNA is more reliable than carcinoembryonic antigen for diagnosis of recurrent esophageal cancer.
J Am Coll Surg 207: 30-5 (2008)
PM ID: 18589358
682: Kaplowitz N, Than TA, Shinohara M, Ji C
Endoplasmic reticulum stress and liver injury.
Semin Liver Dis 27: 367-77 (2008)
PM ID: 17979073
683: Leigh Pearce C, Near AM, Butler JL, Van Den Berg D, Bretsky P, Conti DV, Stram DO, Pike MC, Hirschhorn JN, Wu AH
Comprehensive evaluation of ESR2 variation and ovarian cancer risk.
Cancer Epidemiol Biomarkers Prev 17: 393-6 (2008)
PM ID: 18268123
684: Tsukamoto H, Mkrtchyan H, Dynnyk A
Intragastric ethanol infusion model in rodents.
Methods Mol Biol 447: 33-48 (2008)
PM ID: 18369909
685: Saberi B, Shinohara M, Ybanez MD, Hanawa N, Gaarde WA, Kaplowitz N, Han D
Regulation of H(2)O(2)-induced necrosis by PKC and AMP-activated kinase signaling in primary cultured hepatocytes.
Am J Physiol Cell Physiol 295: C50-63 (2008)
PM ID: 18463227 PMC2493548
686: Kozuch PS, Rocha-Lima CM, Dragovich T, Hochster HS, O'Neil BH, Atiq OT, Pipas JM, Ryan DP, Lenz HJ
Bortezomib with or without irinotecan in relapsed or refractory colorectal cancer: results from a randomized phase II study.
J Clin Oncol 26: 2320-6 (2008)
PM ID: 18467723
687: Basile LA, Gallaher TK, Shibata D, Miller JD, Douer D
Multilineage hematopoietic recovery with concomitant antitumor effects using low dose Interleukin-12 in myelosuppressed tumor-bearing mice.
J Transl Med 6: 26 (2008)
PM ID: 18489769 PMC2424034
688: Byun HM, Choi SH, Laird PW, Trinh BN, Siddiqui MA, Marquez VE, Yang AS
2'-Deoxy-N4-[2-(4-nitrophenyl)ethoxycarbonyl]-5-azacytidine: a novel inhibitor of DNA methyltransferase that requires activation by human carboxylesterase 1.
Cancer Lett 266: 238-48 (2008)
PM ID: 18499340 PMC2528876 NIHMS57985
689: Cui Y, Morgenstern H, Greenland S, Tashkin DP, Mao JT, Cai L, Cozen W, Mack TM, Lu QY, Zhang ZF
Dietary flavonoid intake and lung cancer--a population-based case-control study.
Cancer 112: 2241-8 (2008)
PM ID: 18327817
690: Press OA, Zhang W, Gordon MA, Yang D, Lurje G, Iqbal S, El-Khoueiry AB, Lenz HJ
Gender-related survival differences associated with EGFR polymorphisms in metastatic colon cancer.
Cancer Res 68: 3037-42 (2008)
PM ID: 18413774
691: Ramus SJ, Vierkant RA, Johnatty SE, Pike MC, Van Den Berg DJ, Wu AH, Pearce CL, Menon U, Gentry-Maharaj A, Gayther SA, DiCioccio RA, McGuire V, Whittemore AS, Song H, Easton DF, Pharoah PD, Garcia-Closas M, Chanock SJ, Lissowska J, Brinton LA, Terry KL, Cramer DW, Tworoger SS, Hankinson SE, Berchuck A, Moorman PG, Schildkraut JM, Cunningham JM, Liebow M, Kjaer SK, Hogdall E, Hogdall CK, Blaakaer J, Ness RB, Moysich KB, Edwards RP, Carney ME, Lurie G, Goodman MT, Wang-Gohrke S, Kropp S, Chang-Claude J, Australian Ovarian Cancer Study Group , Australian Cancer Study (Ovarian Cancer) , Webb PM, Chen X, Beesley J, Chenevix-Trench G, Goode EL, Ovarian Cancer Association Consortium
Consortium analysis of 7 candidate SNPs for ovarian cancer.
Int J Cancer 123: 380-8 (2008)
PM ID: 18431743 PMC2667795 NIHMS104109
692: Al-Mawsawi LQ, Hombrouck A, Dayam R, Debyser Z, Neamati N
Four-tiered pi interaction at the dimeric interface of HIV-1 integrase critical for DNA integration and viral infectivity.
Virology 377: 355-63 (2008)
PM ID: 18514248
693: Lurje G, Zhang W, Schultheis AM, Yang D, Groshen S, Hendifar AE, Husain H, Gordon MA, Nagashima F, Chang HM, Lenz HJ
Polymorphisms in VEGF and IL-8 predict tumor recurrence in stage III colon cancer.
Ann Oncol 19: 1734-41 (2008)
PM ID: 18550579 PMC2735064
694: Stovall M, Smith SA, Langholz BM, Boice JD, Shore RE, Andersson M, Buchholz TA, Capanu M, Bernstein L, Lynch CF, Malone KE, Anton-Culver H, Haile RW, Rosenstein BS, Reiner AS, Thomas DC, Bernstein JL, Women's Environmental, Cancer, and Radiation Epide
Dose to the contralateral breast from radiotherapy and risk of second primary breast cancer in the WECARE study.
Int J Radiat Oncol Biol Phys 72: 1021-30 (2008)
PM ID: 18556141
695: Siegmund KD, Marjoram P, Shibata D
Modeling DNA methylation in a population of cancer cells.
Stat Appl Genet Mol Biol 7: Article 18 (2008)
PM ID: 18597664
696: Liang C, Sir D, Lee SY, Ou JH, Jung JU
Beyond autophagy: the role of UVRAG in membrane trafficking.
Autophagy 4: 817-20 (2008)
PM ID: 18612260
697: Fallon MB, Krowka MJ, Brown RS, Trotter JF, Zacks S, Roberts KE, Shah VH, Kaplowitz N, Forman L, Wille K, Kawut SM, Pulmonary Vascular Complications of Liver Disease
Impact of hepatopulmonary syndrome on quality of life and survival in liver transplant candidates.
Gastroenterology 135: 1168-75 (2008)
PM ID: 18644373
698: Garofalo A, Grande F, Brizzi A, Aiello F, Dayam R, Neamati N
Naphthoxazepine inhibitors of HIV-1 integrase: synthesis and biological evaluation.
ChemMedChem 3: 986-90 (2008)
PM ID: 18383063
699: Ji C, Shinohara M, Vance D, Than TA, Ookhtens M, Chan CK, Kaplowitz N
Effect of transgenic extrahepatic expression of betaine-homocysteine methyltransferase on alcohol or homocysteine-induced fatty liver.
Alcohol Clin Exp Res 32: 1049-58 (2008)
PM ID: 18498552 PMC2596885 NIHMS79996
700: Conti PS, McEwan AJ, Pomper MG
Molecular imaging: the future of modern medicine.
J Nucl Med 49: 16N-20N (2008)
PM ID: 18511813
701: Xiong S, She H, Zhang AS, Wang JG, Mkrtchyan H, Dynnyk A, Gordeuk VR, French SW, Enns CA, Tsukamoto H
Hepatic macrophage iron aggravates experimental alcoholic steatohepatitis.
Am J Physiol Gastrointest Liver Physiol 295: G512-21 (2008)
PM ID: 18599584 PMC2536779
702: Anglim PP, Galler JS, Koss MN, Hagen JA, Turla S, Campan M, Weisenberger DJ, Laird PW, Siegmund KD, Laird-Offringa IA
Identification of a panel of sensitive and specific DNA methylation markers for squamous cell lung cancer.
Mol Cancer 7: 62 (2008)
PM ID: 18616821 PMC2483990
703: Weisenberger DJ, Trinh BN, Campan M, Sharma S, Long TI, Ananthnarayan S, Liang G, Esteva FJ, Hortobagyi GN, McCormick F, Jones PA, Laird PW
DNA methylation analysis by digital bisulfite genomic sequencing and digital MethyLight.
Nucleic Acids Res 36: 4689-98 (2008)
PM ID: 18628296 PMC2504308
704: Sir D, Liang C, Chen WL, Jung JU, Ou JH
Perturbation of autophagic pathway by hepatitis C virus.
Autophagy 4: 830-1 (2008)
PM ID: 18635950 PMC2574555 [Available on 11/01/09] NIHMS60148 [Available on 11/01/09]
705: Mello T, Nakatsuka A, Fears S, Davis WW, Tsukamoto H, Bosron WF, Sanghani SP
Expression of carboxylesterase and lipase genes in rat liver cell-types.
Biochem Biophys Res Commun 374: 460-4 (2008)
PM ID: 18639528 PMC2566784 NIHMS66523
706: Somlo G, Chu P, Frankel P, Ye W, Groshen S, Doroshow JH, Danenberg K, Danenberg P
Molecular profiling including epidermal growth factor receptor and p21 expression in high-risk breast cancer patients as indicators of outcome.
Ann Oncol 19: 1853-9 (2008)
PM ID: 18641005 PMC2733077 [Available on 11/01/09]
707: Zeng LF, Jiang XH, Sanchez TW, Zhang HS, Dayam R, Neamati N, Long YQ
Novel dimeric aryldiketo containing inhibitors of HIV-1 integrase: effects of the phenyl substituent and the linker orientation.
Bioorg Med Chem 16: 7777-87 (2008)
PM ID: 18644730
708: Makino H, Uetake H, Danenberg K, Danenberg PV, Sugihara K
Efficacy of laser capture microdissection plus RT-PCR technique in analyzing gene expression levels in human gastric cancer and colon cancer.
BMC Cancer 8: 210 (2008)
PM ID: 18652704 PMC2533342
709: Zeng LF, Zhang HS, Wang YH, Sanchez TW, Zheng YT, Neamati N, Long YQ
Efficient synthesis and utilization of phenyl-substituted heteroaromatic carboxylic acids as aryl diketo acid isosteres in the design of novel HIV-1 integrase inhibitors.
Bioorg Med Chem Lett 18: 4521-4 (2008)
PM ID: 18662877
710: Holschneider DP, Yang JS, Sadler TR, Galifianakis NB, Bozorgzadeh MH, Bading JR, Conti PS, Maarek JM
Changes in regional brain perfusion during functional brain activation: comparison of [(64)Cu]-PTSM with [(14)C]-Iodoantipyrine.
Brain Res 1234: 32-43 (2008)
PM ID: 18687316 PMC2578839 NIHMS73066
711: Tsukamoto H, She H, Hazra S, Cheng JP, Wang JG
Fat paradox of steatohepatitis.
J Gastroenterol Hepatol 23 Suppl 1: S104-7 (2008)
PM ID: 18336651
712: Gutschow CA, Vallböhmer D, Stolte M, Oh D, Danenberg K, Danenberg P, Schneider PM, Hölscher AH
Adenocarcinoma developing in de novo Barrett's mucosa in the remnant esophagus after esophagectomy: clinical and molecular assessment.
Dis Esophagus 21: E6-8 (2008)
PM ID: 18430096
713: Kawut SM, Krowka MJ, Trotter JF, Roberts KE, Benza RL, Badesch DB, Taichman DB, Horn EM, Zacks S, Kaplowitz N, Brown RS, Fallon MB, Pulmonary Vascular Complications of Liver Disease
Clinical risk factors for portopulmonary hypertension.
Hepatology 48: 196-203 (2008)
PM ID: 18537192
714: Al-Mawsawi LQ, Al-Safi RI, Neamati N
Anti-infectives: clinical progress of HIV-1 integrase inhibitors.
Expert Opin Emerg Drugs 13: 213-25 (2008)
PM ID: 18537517
715: Wu AH, Koh WP, Wang RH, Lee HP, Yu MC
Soy intake and breast cancer risk in Singapore Chinese Health Study.
Br J Cancer 99: 196-200 (2008)
PM ID: 18594543 PMC2453029 NIHMS67254
716: Kulke MH, Lenz HJ, Meropol NJ, Posey J, Ryan DP, Picus J, Bergsland EK, Stuart K, Tye L, Huang X, Li JZ, Baum CM, Fuchs CS
Activity of sunitinib in patients with advanced neuroendocrine tumors.
J Clin Oncol 26: 3403-10 (2008)
PM ID: 18612155
717: Hoffmann AC, Mori R, Vallbohmer D, Brabender J, Drebber U, Baldus SE, Klein EA, Azuma M, Metzger R, Hoffmann C, Hoelscher AH, Danenberg KD, Prenzel KL, Danenberg PV
High expression of heparanase is significantly associated with dedifferentiation and lymph node metastasis in patients with pancreatic ductal adenocarcinomas and correlated to PDGFA and via HIF1a to HB-EGF and bFGF.
J Gastrointest Surg 12: 1674-81; discussion 1681-2 (2008)
PM ID: 18704599
718: Yuan L, Kaplowitz N
Glutathione in liver diseases and hepatotoxicity.
Mol Aspects Med 30: 29-41 (2008)
PM ID: 18786561
719: Ramkumar K, Tambov KV, Gundla R, Manaev AV, Manaev AV, Yarovenko V, Traven VF, Neamati N
Discovery of 3-acetyl-4-hydroxy-2-pyranone derivatives and their difluoridoborate complexes as a novel class of HIV-1 integrase inhibitors.
Bioorg Med Chem 16: 8988-98 (2008)
PM ID: 18805696
720: Cozen W, Avol E, Diaz-Sanchez D, McConnell R, Gauderman WJ, Cockburn MG, Zadnick J, Jyrala M, Mack TM
Use of an electrostatic dust cloth for self-administered home allergen collection.
Twin Res Hum Genet 11: 150-5 (2008)
PM ID: 18361715
721: Gundla R, Kazemi R, Sanam R, Muttineni R, Sarma JA, Dayam R, Neamati N
Discovery of novel small-molecule inhibitors of human epidermal growth factor receptor-2: combined ligand and target-based approach.
J Med Chem 51: 3367-77 (2008)
PM ID: 18500794
722: Pohl A, Lurje G, Kahn ML, Lenz HJ
Stem cells in colon cancer.
Clin Colorectal Cancer 7: 92-8 (2008)
PM ID: 18501067
723: Hoffmann AC, Mori R, Vallbohmer D, Brabender J, Klein EA, Drebber U, Baldus SE, Cooc J, Azuma M, Metzger R, Hoelscher AH, Danenberg KD, Prenzel KL, Danenberg PV
High expression of HIF1a is a predictor of clinical outcome in patients with pancreatic ductal adenocarcinomas and correlated to PDGFA, VEGF, and bFGF.
Neoplasia 10: 674-9 (2008)
PM ID: 18592007 PMC2435004
724: Jiang X, Castelao JE, Groshen S, Cortessis VK, Shibata DK, Conti DV, Gago-Dominguez M
Water intake and bladder cancer risk in Los Angeles County.
Int J Cancer 123: 1649-56 (2008)
PM ID: 18623082
725: Mori R, Wang QS, Danenberg KD, Pinski JK, Danenberg PV
Both beta-actin and GAPDH are useful reference genes for normalization of quantitative RT-PCR in human FFPE tissue samples of prostate cancer.
Prostate 68: 1555-60 (2008)
PM ID: 18651557
726: Kaplowitz N, Shinohara M, Liu ZX, Han D
How to protect against acetaminophen: don't ask for JUNK.
Gastroenterology 135: 1047-51 (2008)
PM ID: 18782575
727: Oh DS, DeMeester SR, Dunst CM, Mori R, Lehman BJ, Kuramochi H, Danenberg K, Danenberg P, Hagen JA, Chandrasoma PT, DeMeester TR
Validation of a rodent model of Barrett's esophagus using quantitative gene expression profiling.
Surg Endosc 23: 1346-52 (2008)
PM ID: 18813976
728: Sir D, Chen WL, Choi J, Wakita T, Yen TS, Ou JH
Induction of incomplete autophagic response by hepatitis C virus via the unfolded protein response.
Hepatology 48: 1054-61 (2008)
PM ID: 18688877 PMC2562598 NIHMS57806
729: Concannon P, Haile RW, Børresen-Dale AL, Rosenstein BS, Gatti RA, Teraoka SN, Diep TA, Jansen L, Atencio DP, Langholz B, Capanu M, Liang X, Begg CB, Thomas DC, Bernstein L, Olsen JH, Malone KE, Lynch CF, Anton-Culver H, Bernstein JL, Women's Environment, Cancer, and Radiation Epidemi
Variants in the ATM gene associated with a reduced risk of contralateral breast cancer.
Cancer Res 68: 6486-91 (2008)
PM ID: 18701470 PMC2562548 NIHMS56668
730: Levine AJ, Wallace K, Tsang S, Haile RW, Saibil F, Ahnen DJ, Cole BF, Barry EL, Munroe DJ, Ali IU, Ueland PM, Baron JA
MTHFR genotype and colorectal adenoma recurrence: data from a double-blind placebo-controlled clinical trial.
Cancer Epidemiol Biomarkers Prev 17: 2409-15 (2008)
PM ID: 18768511 PMC2692038 NIHMS90375
731: Wilson PM, Fazzone W, LaBonte MJ, Deng J, Neamati N, Ladner RD
Novel opportunities for thymidylate metabolism as a therapeutic target.
Mol Cancer Ther 7: 3029-37 (2008)
PM ID: 18790783 PMC2597111 NIHMS68743
732: Lopes EC, Valls E, Figueroa ME, Mazur A, Meng FG, Chiosis G, Laird PW, Schreiber-Agus N, Greally JM, Prokhortchouk E, Melnick A
Kaiso contributes to DNA methylation-dependent silencing of tumor suppressor genes in colon cancer cell lines.
Cancer Res 68: 7258-63 (2008)
PM ID: 18794111
733: Sechi M, Azzena U, Delussu MP, Dallocchio R, Dessì A, Cosseddu A, Pala N, Neamati N
Design and synthesis of bis-amide and hydrazide-containing derivatives of malonic acid as potential HIV-1 integrase inhibitors.
Molecules 13: 2442-61 (2008)
PM ID: 18830166
734: McIntosh M, Anderson GL, Drescher C, Hanash S, Urban N, Brown PO, Gambhir SS, Coukos G, Laird PW, Nelson B, Palmer C
Ovarian cancer early detection claims are biased.
Clin Cancer Res 14: 7574; author reply 7577-9 (2008)
PM ID: 18948385
735: Yuksek K, Chen WL, Chien D, Ou JH
Ubiquitin-independent degradation of hepatitis C virus F protein.
J Virol 83: 612-21 (2008)
PM ID: 18971267 PMC2612388
736: Wen X, Zou Y, Luo W, Goldberg MT, Moats RA, Conti PS, Snead ML, Paine ML
Biglycan overexpression on tooth enamel formation in transgenic mice.
Anat Rec (Hoboken) 291: 1246-53 (2008)
PM ID: 18727043 PMC2562349 NIHMS59958
737: Wilson PM, Fazzone W, LaBonte MJ, Lenz HJ, Ladner RD
Regulation of human dUTPase gene expression and p53-mediated transcriptional repression in response to oxaliplatin-induced DNA damage.
Nucleic Acids Res 37: 78-95 (2008)
PM ID: 19015155 PMC2615606
738: Sechi M, Rizzi G, Bacchi A, Carcelli M, Rogolino D, Pala N, Sanchez TW, Taheri L, Dayam R, Neamati N
Design and synthesis of novel dihydroquinoline-3-carboxylic acids as HIV-1 integrase inhibitors.
Bioorg Med Chem 17: 2925-35 (2008)
PM ID: 19026554
739: Joshi AD, Corral R, Siegmund KD, Haile RW, Le Marchand L, Martínez ME, Ahnen DJ, Sandler RS, Lance P, Stern MC
Red meat and poultry intake, polymorphisms in the nucleotide excision repair and mismatch repair pathways and colorectal cancer risk.
Carcinogenesis 30: 472-9 (2008)
PM ID: 19029193 PMC2722151 [Available on 03/01/10]
740: Jadvar H, Ye W, Groshen S, Conti PS
[F-18]-fluorodeoxyglucose PET-CT of the normal prostate gland.
Ann Nucl Med 22: 787-93 (2008)
PM ID: 19039557 PMC2636719 NIHMS78292
741: Figueiredo JC, Levine AJ, Grau MV, Midttun O, Ueland PM, Ahnen DJ, Barry EL, Tsang S, Munroe D, Ali I, Haile RW, Sandler RS, Baron JA
Vitamins B2, B6, and B12 and risk of new colorectal adenomas in a randomized trial of aspirin use and folic acid supplementation.
Cancer Epidemiol Biomarkers Prev 17: 2136-45 (2008)
PM ID: 18708408 PMC2518404 NIHMS56152
742: Mori R, Xiong S, Wang QS, Tarabolous C, Shimada H, Panteris E, Danenberg KD, Danenberg PV, Pinski JK
Gene profiling and pathway analysis of neuroendocrine transdifferentiated prostate cancer cells.
Prostate 69: 12-23 (2008)
PM ID: 18814146
743: Figueiredo JC, Levine AJ, Grau MV, Barry EL, Ueland PM, Ahnen DJ, Byers T, Bresalier RS, Summers RW, Bond JH, McKeown-Eyssen GE, Sandler RS, Haile RW, Baron JA
Colorectal adenomas in a randomized folate trial: the role of baseline dietary and circulating folate levels.
Cancer Epidemiol Biomarkers Prev 17: 2625-31 (2008)
PM ID: 18843003 PMC2597215 NIHMS64547
744: Allen WL, Coyle VM, Jithesh PV, Proutski I, Stevenson L, Fenning C, Longley DB, Wilson RH, Gordon M, Lenz HJ, Johnston PG
Clinical determinants of response to irinotecan-based therapy derived from cell line models.
Clin Cancer Res 14: 6647-55 (2008)
PM ID: 18927307
745: Pohl A, Lurje G, Manegold PC, Lenz HJ
Pharmacogenomics and -genetics in colorectal cancer.
Adv Drug Deliv Rev 61: 375-80 (2008)
PM ID: 19100300
746: Cleary SP, Cotterchio M, Jenkins MA, Kim HJ, Bristow R, Green R, Haile R, Hopper JL, LeMarchand L, Lindor NM, Parfrey P, Potter JD, Younghusband B, Gallinger S
Germline MutY human homologue mutations and colorectal cancer: a multisite case-control study.
Gastroenterology 136: 1251-60 (2008)
PM ID: 19245865 PMC2739726 [Available on 04/01/10] NIHMS139683 [Available on 04/01/10]
747: Etzioni DA, El-Khoueiry AB, Beart RW
Rates and predictors of chemotherapy use for stage III colon cancer: a systematic review.
Cancer 113: 3279-89 (2009)
PM ID: 18951522
748: Schultheis AM, Lurje G, Rhodes KE, Zhang W, Yang D, Garcia AA, Morgan RJ, Gandara D, Scudder S, Oza AM, Hirte H, Fleming GF, Roman LD, Lenz HJ
Polymorphisms and clinical outcome in recurrent ovarian cancer treated with cyclophosphamide and bevacizumab.
Clin Cancer Res 14: 7554-63 (2009)
PM ID: 19010874 PMC2586993 [Available on 11/15/09] NIHMS74084 [Available on 11/15/09]
749: Olsen CM, Zens MS, Stukel TA, Sacerdote C, Chang YM, Armstrong BK, Bataille V, Berwick M, Elwood JM, Holly EA, Kirkpatrick CS, Mack TM, Bishop JN, Østerlind A, Swerdlow AJ, Zanetti R, Green AC, Karagas MR, Whiteman DC
Nevus density and melanoma risk in women: a pooled analysis to test the divergent pathway hypothesis.
Int J Cancer 124: 937-44 (2009)
PM ID: 19035450 PMC2729286 [Available on 02/15/10] NIHMS98767 [Available on 02/15/10]
750: Wu AH, Ursin G, Koh WP, Wang RH, Yuan JM, Khoo KS, Yu MC
Green tea, soy, and mammographic density in Singapore Chinese women.
Cancer Epidemiol Biomarkers Prev 17: 3358-65 (2009)
PM ID: 19064551 PMC2737719 [Available on 12/01/09] NIHMS122763 [Available on 12/01/09]
751: Palmieri RT, Wilson MA, Iversen ES, Clyde MA, Calingaert B, Moorman PG, Poole C, Anderson AR, Anderson SA, Anton-Culver H, Beesley J, Hogdall E, Brewster W, Carney ME, Chen X, Chenevix-Trench G, Chang-Claude J, Cunningham JM, DiCioccio RA, Doherty JA, Easton DF, Edlund CK, Gayther SA, Gentry-Maharaj A, Goode EL, Goodman MT, Kjaer SK, Hogdall CK, Hopkins MP, Jenison EL, Blaakaer J, Lurie G, McGuire V, Menon U, Moysich KB, Ness RB, Pearce CL, Pharoah PD, Pike MC, Ramus SJ, Rossing MA, Song H, Terada KY, VanDenBerg D, Vierkant RA, Wang-Gohrke S, Webb PM, Whittemore AS, Wu AH, Ziogas A, Berchuck A, Schildkraut JM, Ovarian Cancer Association Consortium , Australian Cancer Study (Ovarian Cancer Group) , Australian Ovarian Cancer Study Group
Polymorphism in the IL18 gene and epithelial ovarian cancer in non-Hispanic white women.
Cancer Epidemiol Biomarkers Prev 17: 3567-72 (2009)
PM ID: 19064572 PMC2664299 [Available on 12/01/09] NIHMS94130 [Available on 12/01/09]
752: Pearce CL, Near AM, Van Den Berg DJ, Ramus SJ, Gentry-Maharaj A, Menon U, Gayther SA, Anderson AR, Edlund CK, Wu AH, Chen X, Beesley J, Webb PM, Holt SK, Chen CS, Doherty JA, Rossing MA, Whittemore AS, McGuire V, DiCioccio RA, Goodman MT, Lurie G, Carney ME, Wilkens LR, Ness RB, Moysich KB, Edwards RD, Jennison E, Kjaer SK, Hogdall E, Hogdall CK, Goode EL, Sellers TA, Vierkant RA, Cunningham JC, Schildkraut JM, Berchuck A, Moorman PG, Iversen ES, Cramer DW, Terry KL, Vitonis AF, Titus-Ernstoff L, Song H, Pharoah PD, Spurdle AB, Anton-Culver H, Ziogas A, Brewster W, Galitovskiy V, Chenevix-Trench G, Australian Cancer Study , Australian Ovarian Cancer Study Group
Validating genetic risk associations for ovarian cancer through the international Ovarian Cancer Association Consortium.
Br J Cancer 100: 412-20 (2009)
PM ID: 19127255 PMC2634713 [Available on 01/27/10]
753: Sechi M, Carta F, Sannia L, Dallocchio R, Dessì A, Al-Safi RI, Neamati N
Design, synthesis, molecular modeling, and anti-HIV-1 integrase activity of a series of photoactivatable diketo acid-containing inhibitors as affinity probes.
Antiviral Res 81: 267-76 (2009)
PM ID: 19135482
754: Ramanathan RK, Belani CP, Singh DA, Tanaka MS, Lenz HJ, Yen Y, Kindler HL, Iqbal S, Longmate J, Mack PC, Lurje G, Gandour-Edwards R, Dancey JE, Gandara DR
A phase II study of lapatinib in patients with advanced biliary tree and hepatocellular cancer.
Cancer Chemother Pharmacol 64: 777-83 (2009)
PM ID: 19169683
755: Machida K, Tsukamoto H, Mkrtchyan H, Duan L, Dynnyk A, Liu HM, Asahina K, Govindarajan S, Ray R, Ou JH, Seki E, Deshaies R, Miyake K, Lai MM
Toll-like receptor 4 mediates synergism between alcohol and HCV in hepatic oncogenesis involving stem cell marker Nanog.
Proc Natl Acad Sci U S A 106: 1548-53 (2009)
PM ID: 19171902 PMC2635765
756: Jiang X, Castelao JE, Groshen S, Cortessis VK, Shibata D, Conti DV, Yuan JM, Pike MC, Gago-Dominguez M
Urinary tract infections and reduced risk of bladder cancer in Los Angeles.
Br J Cancer 100: 834-9 (2009)
PM ID: 19174821 PMC2653778 [Available on 03/10/10]
757: Tatsukawa H, Fukaya Y, Frampton G, Martinez-Fuentes A, Suzuki K, Kuo TF, Nagatsuma K, Shimokado K, Okuno M, Wu J, Iismaa S, Matsuura T, Tsukamoto H, Zern MA, Graham RM, Kojima S
Role of transglutaminase 2 in liver injury via cross-linking and silencing of transcription factor Sp1.
Gastroenterology 136: 1783-95.e10 (2009)
PM ID: 19208340
758: Poynter JN, Siegmund KD, Weisenberger DJ, Long TI, Thibodeau SN, Lindor NM, Young JP, Jenkins MA, Hopper JL, Baron JA, Buchanan D, Casey GR, Levine AJ, Le Marchand L, Gallinger S, Bapat B, Potter JD, Newcomb PA, Haile RW, Laird PW, Colon Cancer Family Registry Investigators
Molecular characterization of MSI-H colorectal cancer by MLHI promoter methylation, immunohistochemistry, and mismatch repair germline mutation screening.
Cancer Epidemiol Biomarkers Prev 17: 3208-15 (2009)
PM ID: 18990764 PMC2628332 [Available on 11/01/09] NIHMS80565 [Available on 11/01/09]
759: Kobayashi H, Sugihara K, Uetake H, Higuchi T, Yasuno M, Enomoto M, Iida S, Azuma M, Mori R, Omori A, Lenz HJ, Danenberg KD, Danenberg PV
Messenger RNA expression of TS and ERCC1 in colorectal cancer and matched liver metastasis.
Int J Oncol 33: 1257-62 (2009)
PM ID: 19020759
760: Lurje G, Nagashima F, Zhang W, Yang D, Chang HM, Gordon MA, El-Khoueiry AB, Husain H, Wilson PM, Ladner RD, Mauro DJ, Langer C, Rowinsky EK, Lenz HJ
Polymorphisms in cyclooxygenase-2 and epidermal growth factor receptor are associated with progression-free survival independent of K-ras in metastatic colorectal cancer patients treated with single-agent cetuximab.
Clin Cancer Res 14: 7884-95 (2009)
PM ID: 19047118
761: Wu AH, Pearce CL, Tseng CC, Templeman C, Pike MC
Markers of inflammation and risk of ovarian cancer in Los Angeles County.
Int J Cancer 124: 1409-15 (2009)
PM ID: 19065661
762: Zawahir Z, Dayam R, Deng J, Pereira C, Neamati N
Pharmacophore guided discovery of small-molecule human apurinic/apyrimidinic endonuclease 1 inhibitors.
J Med Chem 52: 20-32 (2009)
PM ID: 19072053
763: Chen JL, Lin HH, Kim KJ, Lin AH, Ou JH, Ann DK
PKC delta signaling: a dual role in regulating hypoxic stress-induced autophagy and apoptosis.
Autophagy 5: 244-6 (2009)
PM ID: 19098423 PMC2743529 NIHMS123596
764: Ohta S, Uemura H, Matsui Y, Ishiguro H, Fujinami K, Kondo K, Miyamoto H, Yazawa T, Danenberg K, Danenberg PV, Tohnai I, Kubota Y
Alterations of p16 and p14ARF genes and their 9p21 locus in oral squamous cell carcinoma.
Oral Surg Oral Med Oral Pathol Oral Radiol Endod 107: 81-91 (2009)
PM ID: 19101490
765: Ley EJ, Scehnet JS, Park R, Schroff S, Dagliyan G, Conti PS, Margulies DR, Salim A
The in vivo effect of propranolol on cerebral perfusion and hypoxia after traumatic brain injury.
J Trauma 66: 154-9; discussion 159-61 (2009)
PM ID: 19131818
766: Duan L, Wu AH, Sullivan-Halley J, Bernstein L
Antacid drug use and risk of esophageal and gastric adenocarcinomas in Los Angeles County.
Cancer Epidemiol Biomarkers Prev 18: 526-33 (2009)
PM ID: 19190141
767: Taylor D, Pearce CL, Hovanessian-Larsen L, Downey S, Spicer DV, Bartow S, Pike MC, Wu AH, Hawes D
Progesterone and estrogen receptors in pregnant and premenopausal non-pregnant normal human breast.
Breast Cancer Res Treat 118: 161-8 (2009)
PM ID: 19205874
768: Grau MV, Sandler RS, McKeown-Eyssen GE, Bresalier RS, Haile RW, Barry EL, Ahnen DJ, Gui J, Summers RW, Baron JA
Nonsteroidal anti-inflammatory drug use after 3 years of aspirin use and colorectal adenoma risk: observational follow-up of a randomized study.
J Natl Cancer Inst 101: 267-76 (2009)
PM ID: 19211442 PMC2644329 [Available on 02/18/10]
769: Knight JA, Bernstein L, Largent JA, Capanu M, Begg CB, Mellemkjær L, Lynch CF, Malone KE, Reiner AS, Liang X, Haile RW, Boice JD, WECARE Study Collaborative Group , Bernstein JL
Alcohol intake and cigarette smoking and risk of a contralateral breast cancer: The Women's Environmental Cancer and Radiation Epidemiology Study.
Am J Epidemiol 169: 962-8 (2009)
PM ID: 19211621 PMC2727227 [Available on 04/15/10]
770: Wu AH, Yu MC, Tseng CC, Stanczyk FZ, Pike MC
Dietary patterns and breast cancer risk in Asian American women.
Am J Clin Nutr 89: 1145-54 (2009)
PM ID: 19211822
771: Roberts KE, Fallon MB, Krowka MJ, Brown RS, Trotter JF, Peter I, Tighiouart H, Knowles JA, Rabinowitz D, Benza RL, Badesch DB, Taichman DB, Horn EM, Zacks S, Kaplowitz N, Kawut SM, Pulmonary Vascular Complications of Liver Disease
Genetic risk factors for portopulmonary hypertension in patients with advanced liver disease.
Am J Respir Crit Care Med 179: 835-42 (2009)
PM ID: 19218192 PMC2675568 [Available on 05/01/10]
772: Quaye L, Song H, Ramus SJ, Gentry-Maharaj A, Høgdall E, DiCioccio RA, McGuire V, Wu AH, Van Den Berg DJ, Pike MC, Wozniak E, Doherty JA, Rossing MA, Ness RB, Moysich KB, Høgdall C, Blaakaer J, Ovarian Cancer Association Consortium , Easton DF, Ponder BA, Jacobs IJ, Menon U, Whittemore AS, Krüger-Kjaer S, Pearce CL, Pharoah PD, Gayther SA
Tagging single-nucleotide polymorphisms in candidate oncogenes and susceptibility to ovarian cancer.
Br J Cancer 100: 993-1001 (2009)
PM ID: 19240718 PMC2661781 [Available on 03/24/10]
773: Li HY, Wang CY, Sanchez TW, Tan Y, Jiang C, Neamati N, Zhao G
Amide-containing diketoacids as HIV-1 integrase inhibitors: synthesis, structure-activity relationship analysis, and biological activity.
Bioorg Med Chem 17: 2913-9 (2009)
PM ID: 19269185
774: Campan M, Weisenberger DJ, Trinh BN, Laird PW
MethyLight.
Methods Mol Biol 507: 325-37 (2009)
PM ID: 18987824
775: Jadvar H, Gurbuz A, Li X, Shahinian A, Conti PS
Choline autoradiography of human prostate cancer xenograft: effect of castration.
Mol Imaging 7: 147-52 (2009)
PM ID: 19123985 PMC2621313 NIHMS78293
776: Ursin G, Lillie EO, Lee EJ, Cockburn MG, Schork NJ, Cozen W, Parisky YR, Hamilton AS, Astrahan MA, Mack TM
The relative importance of genetics and environment on mammographic density.
Cancer Epidemiol Biomarkers Prev 18: 102-12 (2009)
PM ID: 19124487
777: Pearce CL, Chung K, Pike MC, Wu AH
Increased ovarian cancer risk associated with menopausal estrogen therapy is reduced by adding a progestin.
Cancer 115: 531-9 (2009)
PM ID: 19127543
778: Woo YJ, Siegmund KD, Tavaré S, Shibata D
Older individuals appear to acquire mitotically older colorectal cancers.
J Pathol 217: 483-8 (2009)
PM ID: 19165870
779: Etzioni DA, Mack TM, Beart RW, Kaiser AM
Diverticulitis in the United States: 1998-2005: changing patterns of disease and treatment.
Ann Surg 249: 210-7 (2009)
PM ID: 19212172
780: Plasencia C, Grande F, Oshima T, Cao X, Yamada R, Sanchez TW, Aiello F, Garofalo A, Neamati N
Discovery of a novel quinoxalinhydrazide with a broad-spectrum anticancer activity.
Cancer Biol Ther 8: 458-65 (2009)
PM ID: 19221468
781: Gao J, Chen J, Kramer M, Tsukamoto H, Zhang AS, Enns CA
Interaction of the hereditary hemochromatosis protein HFE with transferrin receptor 2 is required for transferrin-induced hepcidin expression.
Cell Metab 9: 217-27 (2009)
PM ID: 19254567 PMC2673483 [Available on 03/01/10] NIHMS100799 [Available on 03/01/10]
782: Bapat B, Lindor NM, Baron JA, Siegmund KD, Li L, Zheng YT, Haile R, Gallinger S, Jass JR, Young JP, Cotterchio M, Jenkins MA, Grove J, Casey GR, Thibodeau SN, Bishop DT, Hopper JL, Ahnen DJ, Newcomb PA, Le Marchand L, Potter JD, Seminara D, Colon Cancer Family Registry
The association of tumor microsatellite instability phenotype with family history of colorectal cancer.
Cancer Epidemiol Biomarkers Prev 18: 967-75 (2009)
PM ID: 19258475 PMC2763617 [Available on 03/01/10] NIHMS139549 [Available on 03/01/10]
783: Siegmund KD, Marjoram P, Woo YJ, Tavaré S, Shibata D
Inferring clonal expansion and cancer stem cell dynamics from DNA methylation patterns in colorectal cancers.
Proc Natl Acad Sci U S A 106: 4828-33 (2009)
PM ID: 19261858 PMC2651202
784: Serrao E, Odde S, Ramkumar K, Neamati N
Raltegravir, elvitegravir, and metoogravir: the birth of "me-too" HIV-1 integrase inhibitors.
Retrovirology 6: 25 (2009)
PM ID: 19265512 PMC2660292
785: Schildkraut JM, Goode EL, Clyde MA, Iversen ES, Moorman PG, Berchuck A, Marks JR, Lissowska J, Brinton LA, Peplonska B, Cunningham JM, Vierkant RA, Rider DN, Chenevix-Trench G, Webb PM, Beesley J, Chen X, Phelan C, Sutphen R, Sellers TA, Pearce L, Wu AH, Van Den Berg D, Conti DV, Elund CK, Anderson R, Goodman MT, Lurie G, Carney ME, Thompson PJ, Gayther SA, Ramus SJ, Jacobs I, Krüger Kjaer S, Hogdall E, Blaakaer J, Hogdall CK, Easton DF, Song H, Pharoah PD, Whittemore AS, McGuire V, Quaye L, Anton-Culver H, Ziogas A, Terry KL, Cramer DW, Hankinson SE, Tworoger SS, Calingaert B, Chanock SJ, Sherman ME, Garcia-Closas M, Australian Ovarian Cancer Study Group
Single nucleotide polymorphisms in the TP53 region and susceptibility to invasive epithelial ovarian cancer.
Cancer Res 69: 2349-57 (2009)
PM ID: 19276375 PMC2666150 [Available on 03/15/10] NIHMS89154 [Available on 03/15/10]
786: Figueiredo JC, Grau MV, Haile RW, Sandler RS, Summers RW, Bresalier RS, Burke CA, McKeown-Eyssen GE, Baron JA
Folic acid and risk of prostate cancer: results from a randomized clinical trial.
J Natl Cancer Inst 101: 432-5 (2009)
PM ID: 19276452 PMC2657096 [Available on 03/18/10]
787: Song H, Ramus SJ, Kjaer SK, DiCioccio RA, Chenevix-Trench G, Pearce CL, Hogdall E, Whittemore AS, McGuire V, Hogdall CK, Blaakaer J, Wu AH, Van Den Berg DJ, Stram DO, Menon U, Gentry-Maharaj A, Jacobs IJ, Webb PM, Beesley J, Chen X, Australian Cancer (Ovarian) Study , Australian Ovarian Cancer Study Group , Rossing MA, Doherty JA, Chang-Claude J, Wang-Gohrke S, Goodman MT, Lurie G, Thompson PJ, Carney ME, Ness RB, Moysich KB, Goode EL, Vierkant RA, Cunningham JM, Anderson SA, Schildkraut JM, Berchuck A, Iversen ES, Moorman PG, Garcia-Closas M, Chanock SJ, Lissowska J, Brinton LA, Anton-Culver H, Ziogas A, Brewster WR, Ponder BA, Easton DF, Gayther SA, Pharoah PD, Ovarian Cancer Association Consortium (OCAC)
Association between invasive ovarian cancer susceptibility and 11 best candidate SNPs from breast cancer genome-wide association study.
Hum Mol Genet 18: 2297-304 (2009)
PM ID: 19304784 PMC2685754
788: Chew HK, Doroshow JH, Frankel P, Margolin KA, Somlo G, Lenz HJ, Gordon M, Zhang W, Yang D, Russell CA, Spicer D, Synold TW, Bayer R, Hantel A, Stiff PJ, Tetef ML, Gandara DR, Albain KS
Phase II studies of gemcitabine and cisplatin in heavily and minimally pretreated metastatic breast cancer.
J Clin Oncol 27: 2163-9 (2009)
PM ID: 19307510 PMC2674003 [Available on 05/01/10]
789: Korde LA, Wu AH, Fears TR, Nomura AM, West DW, Kolonel LN, Pike MC, Hoover RN, Ziegler RG
Childhood soy intake and breast cancer risk in Asian American women.
Cancer Epidemiol Biomarkers Prev 18: 1050-9 (2009)
PM ID: 19318430
790: Shibata SI, Doroshow JH, Frankel P, Synold TW, Yen Y, Gandara DR, Lenz HJ, Chow WA, Leong LA, Lim D, Margolin KA, Morgan RJ, Somlo G, Newman EM
Phase I trial of GTI-2040, oxaliplatin, and capecitabine in the treatment of advanced metastatic solid tumors: a California Cancer Consortium Study.
Cancer Chemother Pharmacol 64: 1149-55 (2009)
PM ID: 19322566
791: Figueiredo JC, Grau MV, Wallace K, Levine AJ, Shen LJ, Hamdan R, Chen X, Bresalier RS, McKeown-Eyssen GE, Haile RW, Baron JA, Issa JP
Global DNA hypomethylation (LINE-1) in the normal colon and lifestyle characteristics and dietary and genetic factors.
Cancer Epidemiol Biomarkers Prev 18: 1041-9 (2009)
PM ID: 19336559 PMC2712652 [Available on 04/01/10] NIHMS112791 [Available on 04/01/10]
792: Bacchi A, Biemmi M, Carcelli M, Carta F, Compari C, Fisicaro E, Rogolino D, Sechi M, Sippel M, Sotriffer CA, Sanchez TW, Neamati N
From ligand to complexes. Part 2. Remarks on human immunodeficiency virus type 1 integrase inhibition by beta-diketo acid metal complexes.
J Med Chem 51: 7253-64 (2009)
PM ID: 18983138
793: Lurje G, Hendifar AE, Schultheis AM, Pohl A, Husain H, Yang D, Manegold PC, Ning Y, Zhang W, Lenz HJ
Polymorphisms in interleukin 1 beta and interleukin 1 receptor antagonist associated with tumor recurrence in stage II colon cancer.
Pharmacogenet Genomics 19: 95-102 (2009)
PM ID: 18987561
794: Asahina K, Tsai SY, Li P, Ishii M, Maxson RE, Sucov HM, Tsukamoto H
Mesenchymal origin of hepatic stellate cells, submesothelial cells, and perivascular mesenchymal cells during mouse liver development.
Hepatology 49: 998-1011 (2009)
PM ID: 19085956 PMC2673117 [Available on 03/01/10] NIHMS98872 [Available on 03/01/10]
795: Sohn KJ, Jang H, Campan M, Weisenberger DJ, Dickhout J, Wang YC, Cho RC, Yates Z, Lucock M, Chiang EP, Austin RC, Choi SW, Laird PW, Kim YI
The methylenetetrahydrofolate reductase C677T mutation induces cell-specific changes in genomic DNA methylation and uracil misincorporation: a possible molecular basis for the site-specific cancer risk modification.
Int J Cancer 124: 1999-2005 (2009)
PM ID: 19123462 PMC2692263 [Available on 05/01/10] NIHMS99332 [Available on 05/01/10]
796: Boros LG, Deng Q, Pandol SJ, Tsukamoto H, Go VL, Lee WN
Ethanol diversely alters palmitate, stearate, and oleate metabolism in the liver and pancreas of rats using the deuterium oxide single tracer.
Pancreas 38: e47-52 (2009)
PM ID: 19248221
797: Messina M, Wu AH
Perspectives on the soy-breast cancer relation.
Am J Clin Nutr 89: 1673S-1679S (2009)
PM ID: 19339397
798: Lara PN, Natale RB, Crowley JJ, Lenz HJ, Redman MW, Carleton JE, Jett J, Langer CJ, Kuebler JP, Dakhil SR, Chansky K, Gandara DR
Phase III trial of irinotecan/cisplatin compared with etoposide/cisplatin in extensive-stage small-cell lung cancer: clinical and pharmacogenomic results from SWOG S0124.
J Clin Oncol 27: 2530-5 (2009)
PM ID: 19349543 PMC2684855 [Available on 05/20/10]
799: Duan L, Wu AH, Sullivan-Halley J, Bernstein L
Passive smoking and risk of oesophageal and gastric adenocarcinomas.
Br J Cancer 100: 1483-5 (2009)
PM ID: 19352383 PMC2694436 [Available on 05/05/10]
800: Kumar SR, Scehnet JS, Ley EJ, Singh J, Krasnoperov V, Liu RM, Manchanda PK, Ladner RD, Hawes D, Weaver FA, Beart RW, Singh G, Nguyen C, Kahn ML, Gill PS
Preferential induction of EphB4 over EphB2 and its implication in colorectal cancer progression.
Cancer Res 69: 3736-45 (2009)
PM ID: 19366806
801: Tsukamoto H, Machida K, Dynnyk A, Mkrtchyan H
"Second hit" models of alcoholic liver disease.
Semin Liver Dis 29: 178-87 (2009)
PM ID: 19387917
802: Deng J, Taheri L, Grande F, Aiello F, Garofalo A, Neamati N
Discovery of novel anticancer compounds based on a quinoxalinehydrazine pharmacophore.
ChemMedChem 3: 1677-86 (2009)
PM ID: 18985651
803: Li Z, Li Q, Yu XJ, Conti PS, Leahy RM
Lesion detection in dynamic FDG-PET using matched subspace detection.
IEEE Trans Med Imaging 28: 230-40 (2009)
PM ID: 19188110
804: Köhne CH, Lenz HJ
Chemotherapy with targeted agents for the treatment of metastatic colorectal cancer.
Oncologist 14: 478-88 (2009)
PM ID: 19411318
805: Kuramochi H, Uchida K, Peters JH, Shimizu D, Vallbohmer D, Schneider S, Danenberg KD, Danenberg PV
Loss of heterozygosity at thymidylate synthase locus in Barrett's metaplasia, dysplasia, and carcinoma sequences.
BMC Cancer 9: 157 (2009)
PM ID: 19460136 PMC2694818
806: Gandara DR, Kawaguchi T, Crowley JJ, Moon J, Furuse K, Kawahara M, Teramukai S, Ohe Y, Kubota K, Williamson SK, Gautschi O, Lenz HJ, McLeod HL, Lara PN, Coltman CA, Fukuoka M, Saijo N, Fukushima M, Mack PC
Japanese-US common-arm analysis of paclitaxel plus carboplatin in advanced non-small-cell lung cancer: a model for assessing population-related pharmacogenomics.
J Clin Oncol 27: 3540-6 (2009)
PM ID: 19470925 PMC2717760 [Available on 07/20/10]
807: Jadvar H, Henderson RW, Conti PS
2-deoxy-2-[F-18]fluoro-D-glucose-positron emission tomography/computed tomography imaging evaluation of esophageal cancer.
Mol Imaging Biol 8: 193-200 (2009)
PM ID: 16565910
808: Cao X, Plasencia C, Kanzaki A, Yang AJ, Burke TR, Neamati N
Elucidation of the molecular mechanisms of a salicylhydrazide class of compounds by proteomic analysis.
Curr Cancer Drug Targets 9: 189-201 (2009)
PM ID: 19275759
809: McEwan AS, Graham MM, Conti PS
SNM molecular imaging summit introduces clinical trials network.
J Nucl Med 50: 18N (2009)
PM ID: 19339670
810: Berman BP, Weisenberger DJ, Laird PW
Locking in on the human methylome.
Nat Biotechnol 27: 341-2 (2009)
PM ID: 19352369
811: Martinez-Balibrea E, Plasencia C, Ginés A, Martinez-Cardús A, Musulén E, Aguilera R, Manzano JL, Neamati N, Abad A
A proteomic approach links decreased pyruvate kinase M2 expression to oxaliplatin resistance in patients with colorectal cancer and in human cell lines.
Mol Cancer Ther 8: 771-8 (2009)
PM ID: 19372549
812: Fazzone W, Wilson PM, LaBonte MJ, Lenz HJ, Ladner RD
Histone deacetylase inhibitors suppress thymidylate synthase gene expression and synergize with the fluoropyrimidines in colon cancer cells.
Int J Cancer 125: 463-73 (2009)
PM ID: 19384949
813: Etzioni DA, Beart RW, Madoff RD, Ault GT
Impact of the aging population on the demand for colorectal procedures.
Dis Colon Rectum 52: 583-90; discussion 590-1 (2009)
PM ID: 19404056
814: Pomerantz MM, Ahmadiyeh N, Jia L, Herman P, Verzi MP, Doddapaneni H, Beckwith CA, Chan JA, Hills A, Davis M, Yao KL, Kehoe SM, Lenz HJ, Haiman CA, Yan C, Henderson BE, Frenkel B, Barretina J, Bass A, Tabernero J, Baselga J, Regan MM, Manak JR, Shivdasani R, Coetzee GA, Freedman ML
The 8q24 cancer risk variant rs6983267 shows long-range interaction with MYC in colorectal cancer.
Nat Genet 41: 882-4 (2009)
PM ID: 19561607 PMC2763485 [Available on 02/01/10] NIHMS120360 [Available on 02/01/10]
815: Fukui Y, Oka T, Nagayama S, Danenberg PV, Danenberg KD, Fukushima M
Thymidylate synthase, dihydropyrimidine dehydrogenase, orotate phosphoribosyltransferase mRNA and protein expression levels in solid tumors in large scale population analysis.
Int J Mol Med 22: 709-16 (2009)
PM ID: 19020767
816: Kobayashi H, Sugihara K, Uetake H, Higuchi T, Yasuno M, Enomoto M, Iida S, Lenz HJ, Danenberg KD, Danenberg PV
Messenger RNA expression of COX-2 and angiogenic factors in primary colorectal cancer and corresponding liver metastasis.
Int J Oncol 34: 1147-53 (2009)
PM ID: 19287974
817: Lu SC, Ramani K, Ou X, Lin MW, Yu V, Ko KS, Park R, Bottiglieri T, Tsukamoto H, Kanel G, French SW, Mato JM, Moats RA, Grant E
S-adenosylmethionine in the chemoprevention and treatment of hepatocellular carcinoma in a rat model.
Hepatology 50: 462-71 (2009)
PM ID: 19444874 PMC2754739 NIHMS117036
818: Cai H, Fissekis JD, Conti PS
Synthesis of a novel bifunctional chelator AmBaSar based on sarcophagine for peptide conjugation and (64)Cu radiolabelling.
Dalton Trans : 5395-400 (2009)
PM ID: 19565091
819: Han D, Ybanez MD, Ahmadi S, Yeh K, Kaplowitz N
Redox regulation of tumor necrosis factor signaling.
Antioxid Redox Signal : (2009)
PM ID: 19361274
820: Lurje G, Manegold PC, Ning Y, Pohl A, Zhang W, Lenz HJ
Thymidylate synthase gene variations: predictive and prognostic markers.
Mol Cancer Ther : (2009)
PM ID: 19383851
821: Asahina K, Tsukamoto H
Reply:
Hepatology 50: 320 (2009)
PM ID: 19554544
822: LaBonte MJ, Manegold PC, Wilson PM, Fazzone W, Louie SG, Lenz HJ, Ladner RD
The dual EGFR/HER-2 tyrosine kinase inhibitor lapatinib sensitizes colon and gastric cancer cells to the irinotecan active metabolite SN-38.
Int J Cancer 125: 2957-2969 (2009)
PM ID: 19536776