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USC Norris Comprehensive Cancer Center
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Publications for Norris Cancer Center Members in the Developmental Therapeutics Program

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Total Number of Publications: 193 (At least 1 author in this program)
Inter Programmatic Publications: 88 (A collaboration outside the program...at least 1 author in the program, and at least 1 author out of the program)
Intra Programmatic Publications: 0 (A collaboration within the program...at least 2 authors in the program)

1: Mitra AP, Cote RJ
Molecular pathogenesis and diagnostics of bladder cancer.
Annu Rev Pathol 4: 251-85 (2009)
PM ID: 18840072
2: Serrao E, Odde S, Ramkumar K, Neamati N
Raltegravir, elvitegravir, and metoogravir: the birth of "me-too" HIV-1 integrase inhibitors.
Retrovirology 6: 25 (2009)
PM ID: 19265512 PMC2660292
3: Kuramochi H, Uchida K, Peters JH, Shimizu D, Vallbohmer D, Schneider S, Danenberg KD, Danenberg PV
Loss of heterozygosity at thymidylate synthase locus in Barrett's metaplasia, dysplasia, and carcinoma sequences.
BMC Cancer 9: 157 (2009)
PM ID: 19460136 PMC2694818
4: Grimminger PP, Stöhlmacher J, Vallböhmer D, Schneider PM, Hölscher AH, Metzger R, Danenberg PV, Brabender J
Prognostic Significance and Clinicopathological Associations of COX-2 SNP in Patients with Nonsmall Cell Lung Cancer.
J Oncol 2009: 139590 (2009)
PM ID: 20016751 PMC2793422
5: Brzozowski Z, Saczewski F, Slawinski J, Sanchez T, Neamati N
Synthesis and anti-HIV-1 integrase activities of 3-aroyl-2,3-dihydro-1,1-dioxo-1,4,2-benzodithiazines.
Eur J Med Chem 44: 190-6 (2009)
PM ID: 18394758
6: Mori R, Xiong S, Wang Q, Tarabolous C, Shimada H, Panteris E, Danenberg KD, Danenberg PV, Pinski JK
Gene profiling and pathway analysis of neuroendocrine transdifferentiated prostate cancer cells.
Prostate 69: 12-23 (2009)
PM ID: 18814146
7: Sherman CB, Ali-Nazir A, Gonzales-Gomez I, Finlay JL, Dhall G
Primary mixed glioneuronal tumor of the central nervous system in a patient with noonan syndrome: a case report and review of the literature.
J Pediatr Hematol Oncol 31: 61-4 (2009)
PM ID: 19125092
8: Javahery RJ, Davidson L, Fangusaro J, Finlay JL, Gonzalez-Gomez I, McComb JG
Aggressive variant of a papillary glioneuronal tumor. Report of 2 cases.
J Neurosurg Pediatr 3: 46-52 (2009)
PM ID: 19119904
9: Park JR, Villablanca JG, London WB, Gerbing RB, Haas-Kogan D, Adkins ES, Attiyeh EF, Maris JM, Seeger RC, Reynolds CP, Matthay KK, Children's Oncology Group
Outcome of high-risk stage 3 neuroblastoma with myeloablative therapy and 13-cis-retinoic acid: a report from the Children's Oncology Group.
Pediatr Blood Cancer 52: 44-50 (2009)
PM ID: 18937318 PMC2731719 NIHMS123682
10: Zawahir Z, Dayam R, Deng J, Pereira C, Neamati N
Pharmacophore guided discovery of small-molecule human apurinic/apyrimidinic endonuclease 1 inhibitors.
J Med Chem 52: 20-32 (2009)
PM ID: 19072053
11: Cheung E, Pinski J, Dorff T, Groshen S, Quinn DI, Reynolds CP, Maurer BJ, Lara PN, Tsao-Wei DD, Twardowski P, Chatta G, McNamara M, Gandara DR
Oral fenretinide in biochemically recurrent prostate cancer: a California cancer consortium phase II trial.
Clin Genitourin Cancer 7: 43-50 (2009)
PM ID: 19213668
12: Ohta S, Uemura H, Matsui Y, Ishiguro H, Fujinami K, Kondo K, Miyamoto H, Yazawa T, Danenberg K, Danenberg PV, Tohnai I, Kubota Y
Alterations of p16 and p14ARF genes and their 9p21 locus in oral squamous cell carcinoma.
Oral Surg Oral Med Oral Pathol Oral Radiol Endod 107: 81-91 (2009)
PM ID: 19101490
13: Youssef RF, Mitra AP, Bartsch G, Jones PA, Skinner DG, Cote RJ
Molecular targets and targeted therapies in bladder cancer management.
World J Urol 27: 9-20 (2009)
PM ID: 19039591
14: Kang MH, Reynolds CP
Bcl-2 inhibitors: targeting mitochondrial apoptotic pathways in cancer therapy.
Clin Cancer Res 15: 1126-32 (2009)
PM ID: 19228717 PMC3182268 NIHMS252838
15: Tsai AG, Engelhart AE, Hatmal MM, Houston SI, Hud NV, Haworth IS, Lieber MR
Conformational variants of duplex DNA correlated with cytosine-rich chromosomal fragile sites.
J Biol Chem 284: 7157-64 (2009)
PM ID: 19106104 PMC2652318
16: Matthay KK, Reynolds CP, Seeger RC, Shimada H, Adkins ES, Haas-Kogan D, Gerbing RB, London WB, Villablanca JG
Long-term results for children with high-risk neuroblastoma treated on a randomized trial of myeloablative therapy followed by 13-cis-retinoic acid: a children's oncology group study.
J Clin Oncol 27: 1007-13 (2009)
PM ID: 19171716 PMC2738615
17: Cao X, Plasencia C, Kanzaki A, Yang A, Burke TR, Neamati N
Elucidation of the molecular mechanisms of a salicylhydrazide class of compounds by proteomic analysis.
Curr Cancer Drug Targets 9: 189-201 (2009)
PM ID: 19275759
18: Plasencia C, Grande F, Oshima T, Cao X, Yamada R, Sanchez T, Aiello F, Garofalo A, Neamati N
Discovery of a novel quinoxalinhydrazide with a broad-spectrum anticancer activity.
Cancer Biol Ther 8: 458-65 (2009)
PM ID: 19221468
19: Sechi M, Carta F, Sannia L, Dallocchio R, Dessì A, Al-Safi RI, Neamati N
Design, synthesis, molecular modeling, and anti-HIV-1 integrase activity of a series of photoactivatable diketo acid-containing inhibitors as affinity probes.
Antiviral Res 81: 267-76 (2009)
PM ID: 19135482
20: Lowe EJ, Sposto R, Perkins SL, Gross TG, Finlay J, Zwick D, Abromowitch M, Children's Cancer Group Study 5941
Intensive chemotherapy for systemic anaplastic large cell lymphoma in children and adolescents: final results of Children's Cancer Group Study 5941.
Pediatr Blood Cancer 52: 335-9 (2009)
PM ID: 18985718 PMC2769495 NIHMS123401
21: Wagner LM, Villablanca JG, Stewart CF, Crews KR, Groshen S, Reynolds CP, Park JR, Maris JM, Hawkins RA, Daldrup-Link HE, Jackson HA, Matthay KK
Phase I trial of oral irinotecan and temozolomide for children with relapsed high-risk neuroblastoma: a new approach to neuroblastoma therapy consortium study.
J Clin Oncol 27: 1290-6 (2009)
PM ID: 19171709 PMC2667827
22: Balic M, Pichler M, Strutz J, Heitzer E, Ausch C, Samonigg H, Cote RJ, Dandachi N
High quality assessment of DNA methylation in archival tissues from colorectal cancer patients using quantitative high-resolution melting analysis.
J Mol Diagn 11: 102-8 (2009)
PM ID: 19179456 PMC2665859
23: Sechi M, Rizzi G, Bacchi A, Carcelli M, Rogolino D, Pala N, Sanchez TW, Taheri L, Dayam R, Neamati N
Design and synthesis of novel dihydroquinoline-3-carboxylic acids as HIV-1 integrase inhibitors.
Bioorg Med Chem 17: 2925-35 (2009)
PM ID: 19026554
24: Aparicio A, North B, Barske L, Wang X, Bollati V, Weisenberger D, Yoo C, Tannir N, Horne E, Groshen S, Jones P, Yang A, Issa JP
LINE-1 methylation in plasma DNA as a biomarker of activity of DNA methylation inhibitors in patients with solid tumors.
Epigenetics 4: 176-84 (2009)
PM ID: 19421002 PMC2848123 NIHMS184539
25: Martinez-Balibrea E, Plasencia C, Ginés A, Martinez-Cardús A, Musulén E, Aguilera R, Manzano JL, Neamati N, Abad A
A proteomic approach links decreased pyruvate kinase M2 expression to oxaliplatin resistance in patients with colorectal cancer and in human cell lines.
Mol Cancer Ther 8: 771-8 (2009)
PM ID: 19372549
26: Kobayashi H, Sugihara K, Uetake H, Higuchi T, Yasuno M, Enomoto M, Iida S, Lenz HJ, Danenberg KD, Danenberg PV
Messenger RNA expression of COX-2 and angiogenic factors in primary colorectal cancer and corresponding liver metastasis.
Int J Oncol 34: 1147-53 (2009)
PM ID: 19287974
27: Grande F, Yamada R, Cao X, Aiello F, Garofalo A, Neamati N
Synthesis and biological evaluation of novel hydrazide based cytotoxic agents.
Expert Opin Investig Drugs 18: 555-68 (2009)
PM ID: 19388873
28: Volchenboum SL, Li C, Li S, Attiyeh EF, Reynolds CP, Maris JM, Look AT, George RE
Comparison of primary neuroblastoma tumors and derivative early-passage cell lines using genome-wide single nucleotide polymorphism array analysis.
Cancer Res 69: 4143-9 (2009)
PM ID: 19435921 PMC2739280 NIHMS119938
29: Oh DS, DeMeester SR, Dunst CM, Mori R, Lehman BJ, Kuramochi H, Danenberg K, Danenberg P, Hagen JA, Chandrasoma P, DeMeester TR
Validation of a rodent model of Barrett's esophagus using quantitative gene expression profiling.
Surg Endosc 23: 1346-52 (2009)
PM ID: 18813976
30: Oshima T, Cao X, Grande F, Yamada R, Garofalo A, Louie S, Neamati N
Combination effects of SC144 and cytotoxic anticancer agents.
Anticancer Drugs 20: 312-20 (2009)
PM ID: 19322070
31: Martinez-Balibrea E, Martínez-Cardús A, Musulén E, Ginés A, Manzano JL, Aranda E, Plasencia C, Neamati N, Abad A
Increased levels of copper efflux transporter ATP7B are associated with poor outcome in colorectal cancer patients receiving oxaliplatin-based chemotherapy.
Int J Cancer 124: 2905-10 (2009)
PM ID: 19296535
32: Rosol M, Harutyunyan I, Xu J, Melendez E, Smbatyan G, Finlay JL, Krieger MD, Gonzalez-Gomez I, Reynolds CP, Nelson MD, Erdreich-Epstein A, Blüml S
Metabolism of orthotopic mouse brain tumor models.
Mol Imaging 8: 199-208 (2009)
PM ID: 19728974
33: Butturini AM, Jacob M, Aguajo J, Vander-Walde NA, Villablanca J, Jubran R, Erdreich-Epstein A, Marachelian A, Dhall G, Finlay JL
High-dose chemotherapy and autologous hematopoietic progenitor cell rescue in children with recurrent medulloblastoma and supratentorial primitive neuroectodermal tumors: the impact of prior radiotherapy on outcome.
Cancer 115: 2956-63 (2009)
PM ID: 19402050
34: Wang DS, Dake MD, Park JM, Kuo MD
Molecular imaging: a primer for interventionalists and imagers.
J Vasc Interv Radiol 20: S505-22 (2009)
PM ID: 19560036
35: Choi SH, Worswick S, Byun HM, Shear T, Soussa JC, Wolff EM, Douer D, Garcia-Manero G, Liang G, Yang AS
Changes in DNA methylation of tandem DNA repeats are different from interspersed repeats in cancer.
Int J Cancer 125: 723-9 (2009)
PM ID: 19437537 PMC4086885 NIHMS587075
36: Mitra AP, Pagliarulo V, Yang D, Waldman FM, Datar RH, Skinner DG, Groshen S, Cote RJ
Generation of a concise gene panel for outcome prediction in urinary bladder cancer.
J Clin Oncol 27: 3929-37 (2009)
PM ID: 19620494 PMC2799152
37: Wang P, Liu C, Sanches T, Zhong Y, Liu B, Xiong J, Neamati N, Zhao G
Design and synthesis of novel nitrogen-containing polyhydroxylated aromatics as HIV-1 integrase inhibitors from caffeic acid phenethyl ester.
Bioorg Med Chem Lett 19: 4574-8 (2009)
PM ID: 19625188
38: Hoffmann AC, Hoffman AC, Danenberg KD, Taubert H, Danenberg PV, Wuerl P
A three-gene signature for outcome in soft tissue sarcoma.
Clin Cancer Res 15: 5191-8 (2009)
PM ID: 19671876
39: Sutch BT, Chambers EJ, Bayramyan MZ, Gallaher TK, Haworth IS
Similarity of protein-RNA interfaces based on motif analysis.
J Chem Inf Model 49: 2139-46 (2009)
PM ID: 19731952
40: Keshelava N, Houghton PJ, Morton CL, Lock RB, Carol H, Keir ST, Maris JM, Reynolds CP, Gorlick R, Kolb EA, Wu J, Smith MA
Initial testing (stage 1) of vorinostat (SAHA) by the pediatric preclinical testing program.
Pediatr Blood Cancer 53: 505-8 (2009)
PM ID: 19418547 PMC2752378 NIHMS123105
41: Morton CL, Houghton PJ, Gorlick R, Kolb EA, Lock R, Carol H, Keir ST, Reynolds CP, Kang MH, Maris JM, Billups C, Smith MA
Initial testing of aplidin by the pediatric pre-clinical testing program.
Pediatr Blood Cancer 53: 509-12 (2009)
PM ID: 19418543 PMC2777698 NIHMS123399
42: Shariat SF, Lotan Y, Karakiewicz PI, Ashfaq R, Isbarn H, Fradet Y, Bastian PJ, Nielsen ME, Capitanio U, Jeldres C, Montorsi F, Müller SC, Karam JA, Heukamp LC, Netto G, Lerner SP, Sagalowsky AI, Cote RJ
p53 predictive value for pT1-2 N0 disease at radical cystectomy.
J Urol 182: 907-13 (2009)
PM ID: 19616250
43: Xu L, Haworth IS, Kulkarni AA, Bolger MB, Davies DL
Mutagenesis and cysteine scanning of transmembrane domain 10 of the human dipeptide transporter.
Pharm Res 26: 2358-66 (2009)
PM ID: 19685173 PMC2861424 NIHMS155693
44: Gorlick R, Kolb EA, Houghton PJ, Morton CL, Phelps D, Schaiquevich P, Stewart C, Keir ST, Lock R, Carol H, Reynolds CP, Maris JM, Wu J, Smith MA
Initial testing (stage 1) of lapatinib by the pediatric preclinical testing program.
Pediatr Blood Cancer 53: 594-8 (2009)
PM ID: 19554571 PMC2731000 NIHMS123092
45: Pathania D, Millard M, Neamati N
Opportunities in discovery and delivery of anticancer drugs targeting mitochondria and cancer cell metabolism.
Adv Drug Deliv Rev 61: 1250-75 (2009)
PM ID: 19716393
46: Katzenstein HM, Chang KW, Krailo M, Chen Z, Finegold MJ, Rowland J, Reynolds M, Pappo A, London WB, Malogolowkin M, Children's Oncology Group
Amifostine does not prevent platinum-induced hearing loss associated with the treatment of children with hepatoblastoma: a report of the Intergroup Hepatoblastoma Study P9645 as a part of the Children's Oncology Group.
Cancer 115: 5828-35 (2009)
PM ID: 19813275 PMC2795100 NIHMS146810
47: Byun HM, Siegmund KD, Pan F, Weisenberger DJ, Kanel G, Laird PW, Yang AS
Epigenetic profiling of somatic tissues from human autopsy specimens identifies tissue- and individual-specific DNA methylation patterns.
Hum Mol Genet 18: 4808-17 (2009)
PM ID: 19776032
48: Sumiyoshi T, Holt NG, Hollis RP, Ge S, Cannon PM, Crooks GM, Kohn DB
Stable transgene expression in primitive human CD34+ hematopoietic stem/progenitor cells, using the Sleeping Beauty transposon system.
Hum Gene Ther 20: 1607-26 (2009)
PM ID: 19689196
49: Chen TT, Rakheja D, Hung JY, Hornsby PJ, Tabaczewski P, Malogolowkin M, Feusner J, Miskevich F, Schultz R, Tomlinson GE
Establishment and characterization of a cancer cell line derived from an aggressive childhood liver tumor.
Pediatr Blood Cancer 53: 1040-7 (2009)
PM ID: 19637320
50: Meyers RL, Rowland JR, Krailo M, Chen Z, Katzenstein HM, Malogolowkin MH
Predictive power of pretreatment prognostic factors in children with hepatoblastoma: a report from the Children's Oncology Group.
Pediatr Blood Cancer 53: 1016-22 (2009)
PM ID: 19588519
51: Carol H, Lock R, Houghton PJ, Morton CL, Kolb EA, Gorlick R, Reynolds CP, Maris JM, Keir ST, Billups CA, Smith MA
Initial testing (stage 1) of the kinesin spindle protein inhibitor ispinesib by the pediatric preclinical testing program.
Pediatr Blood Cancer 53: 1255-63 (2009)
PM ID: 19554570 PMC2763980 NIHMS123095
52: O'Day SJ, Atkins MB, Boasberg P, Wang HJ, Thompson JA, Anderson CM, Gonzalez R, Lutzky J, Amatruda T, Hersh EM, Weber JS
Phase II multicenter trial of maintenance biotherapy after induction concurrent Biochemotherapy for patients with metastatic melanoma.
J Clin Oncol 27: 6207-12 (2009)
PM ID: 19917850
53: Spreafico F, Pritchard Jones K, Malogolowkin MH, Bergeron C, Hale J, de Kraker J, Dallorso S, Acha T, de Camargo B, Dome JS, Graf N
Treatment of relapsed Wilms tumors: lessons learned.
Expert Rev Anticancer Ther 9: 1807-15 (2009)
PM ID: 19954292
54: Ramajayam R, Mahera NB, Neamati N, Yadav MR, Giridhar R
Synthesis and anti-HIV-1 integrase activity of cyano pyrimidinones.
Arch Pharm (Weinheim) 342: 710-5 (2009)
PM ID: 19899101
55: Millard M, Pathania D, Shabaik Y, Taheri L, Deng J, Neamati N
Preclinical evaluation of novel triphenylphosphonium salts with broad-spectrum activity.
PLoS One 5: (2010)
PM ID: 20957228 PMC2949386
56: Kapranov P, St Laurent G, Raz T, Ozsolak F, Reynolds CP, Sorensen PH, Reaman G, Milos P, Arceci RJ, Thompson JF, Triche TJ
The majority of total nuclear-encoded non-ribosomal RNA in a human cell is 'dark matter' un-annotated RNA.
BMC Biol 8: 149 (2010)
PM ID: 21176148 PMC3022773
57: Birkhahn M, Mitra AP, Williams AJ, Lam G, Ye W, Datar RH, Balic M, Groshen S, Steven KE, Cote RJ
Predicting recurrence and progression of noninvasive papillary bladder cancer at initial presentation based on quantitative gene expression profiles.
Eur Urol 57: 12-20 (2010)
PM ID: 19762144 PMC2828516 NIHMS144072
58: Shariat SF, Bolenz C, Karakiewicz PI, Fradet Y, Ashfaq R, Bastian PJ, Nielsen ME, Capitanio U, Jeldres C, Rigaud J, Müller SC, Lerner SP, Montorsi F, Sagalowsky AI, Cote RJ, Lotan Y
p53 expression in patients with advanced urothelial cancer of the urinary bladder.
BJU Int 105: 489-95 (2010)
PM ID: 19659466
59: Smith MA, Morton CL, Kolb EA, Gorlick R, Keir ST, Carol H, Lock R, Kang MH, Reynolds CP, Maris JM, Watkins AE, Houghton PJ
Initial testing (stage 1) of mapatumumab (HGS-ETR1) by the pediatric preclinical testing program.
Pediatr Blood Cancer 54: 307-10 (2010)
PM ID: 19856388 PMC2794954 NIHMS123744
60: Yamada R, Kostova MB, Anchoori RK, Xu S, Neamati N, Khan SR
Biological evaluation of paclitaxel-peptide conjugates as a model for MMP2-targeted drug delivery.
Cancer Biol Ther 9: 192-203 (2010)
PM ID: 20023432
61: Sanam R, Tajne S, Gundla R, Vadivelan S, Machiraju PK, Dayam R, Narasu L, Jagarlapudi S, Neamati N
Combined pharmacophore and structure-guided studies to identify diverse HSP90 inhibitors.
J Mol Graph Model 28: 472-7 (2010)
PM ID: 20005756
62: Dunkel IJ, Jubran RF, Gururangan S, Chantada GL, Finlay JL, Goldman S, Khakoo Y, O'Brien JM, Orjuela M, Rodriguez-Galindo C, Souweidane MM, Abramson DH
Trilateral retinoblastoma: potentially curable with intensive chemotherapy.
Pediatr Blood Cancer 54: 384-7 (2010)
PM ID: 19908299
63: Dunkel IJ, Gardner SL, Garvin JH, Goldman S, Shi W, Finlay JL
High-dose carboplatin, thiotepa, and etoposide with autologous stem cell rescue for patients with previously irradiated recurrent medulloblastoma.
Neuro Oncol 12: 297-303 (2010)
PM ID: 20167818 PMC2940591
64: Serowka K, Chiu Y, Gonzalez I, Gilles F, McComb G, Krieger M, Dhall G, Britt B, Ji L, Sposto R, Finlay JL
Central nervous system (CNS) tumors in the first six months of life: the Children's Hospital Los Angeles experience, 1979-2005.
Pediatr Hematol Oncol 27: 90-102 (2010)
PM ID: 20201690
65: da Silva NS, Cappellano AM, Diez B, Cavalheiro S, Gardner S, Wisoff J, Kellie S, Parker R, Garvin J, Finlay J
Primary chemotherapy for intracranial germ cell tumors: results of the third international CNS germ cell tumor study.
Pediatr Blood Cancer 54: 377-83 (2010)
PM ID: 20063410
66: Sands SA, Oberg JA, Gardner SL, Whiteley JA, Glade-Bender JL, Finlay JL
Neuropsychological functioning of children treated with intensive chemotherapy followed by myeloablative consolidation chemotherapy and autologous hematopoietic cell rescue for newly diagnosed CNS tumors: an analysis of the Head Start II survivors.
Pediatr Blood Cancer 54: 429-36 (2010)
PM ID: 20052775
67: Shamberger RC, Anderson JR, Breslow NE, Perlman EJ, Beckwith JB, Ritchey ML, Haase GM, Donaldson M, Grundy PE, Weetman R, Coppes MJ, Malogolowkin M, Shearer PD, Kletzel M, Thomas PR, Macklis R, Huff V, Weeks DA, Green DM
Long-term outcomes for infants with very low risk Wilms tumor treated with surgery alone in National Wilms Tumor Study-5.
Ann Surg 251: 555-8 (2010)
PM ID: 20142733 PMC2836016 NIHMS169913
68: Grimminger PP, Schneider PM, Metzger R, Vallböhmer D, Danenberg KD, Danenberg PV, Hölscher AH, Brabender J
Ornithine decarboxylase mRNA expression in curatively resected non-small-cell lung cancer.
Clin Lung Cancer 11: 114-9 (2010)
PM ID: 20199977
69: Kuramochi H, Hayashi K, Nakajima G, Kamikozuru H, Yamamoto M, Danenberg KD, Danenberg PV
Epidermal growth factor receptor (EGFR) mRNA levels and protein expression levels in primary colorectal cancer and corresponding liver metastases.
Cancer Chemother Pharmacol 65: 825-31 (2010)
PM ID: 19701635
70: Wolff EM, Byun HM, Han HF, Sharma S, Nichols PW, Siegmund KD, Yang AS, Jones PA, Liang G
Hypomethylation of a LINE-1 promoter activates an alternate transcript of the MET oncogene in bladders with cancer.
PLoS Genet 6: e1000917 (2010)
PM ID: 20421991 PMC2858672
71: Si SJ, Khatua S, Dhall G, Nelson MD, Gonzalez-Gomez I, Finlay JL
Regression of primary central nervous system germinoma after dexamethasone administration: a case report.
Pediatr Hematol Oncol 27: 237-43 (2010)
PM ID: 20367268
72: Tabori U, Shlien A, Baskin B, Levitt S, Ray P, Alon N, Hawkins C, Bouffet E, Pienkowska M, Lafay-Cousin L, Gozali A, Zhukova N, Shane L, Gonzalez I, Finlay J, Malkin D
TP53 alterations determine clinical subgroups and survival of patients with choroid plexus tumors.
J Clin Oncol 28: 1995-2001 (2010)
PM ID: 20308654
73: Finlay JL, Massimino M
A consensus and state-of-the-art workshop: marrow ablative chemotherapy with hematopoietic cell rescue for malignant brain tumors of childhood and adolescence.
Pediatr Blood Cancer 54: 634 (2010)
PM ID: 20146221
74: Massimino M, Cohen KJ, Finlay JL
Is there a role for myeloablative chemotherapy with autologous hematopoietic cell rescue in the management of childhood high-grade astrocytomas?
Pediatr Blood Cancer 54: 641-3 (2010)
PM ID: 20146219
75: Rutkowski S, Cohen B, Finlay J, Luksch R, Ridola V, Valteau-Couanet D, Hara J, Garre ML, Grill J
Medulloblastoma in young children.
Pediatr Blood Cancer 54: 635-7 (2010)
PM ID: 20146217
76: Les AS, Shadden SC, Figueroa CA, Park JM, Tedesco MM, Herfkens RJ, Dalman RL, Taylor CA
Quantification of hemodynamics in abdominal aortic aneurysms during rest and exercise using magnetic resonance imaging and computational fluid dynamics.
Ann Biomed Eng 38: 1288-313 (2010)
PM ID: 20143263
77: Romero RM, Eriksen SP, Haworth IS
Quantitative assessment of assisted problem-based learning in a pharmaceutics course.
Am J Pharm Educ 74: 66 (2010)
PM ID: 20585427 PMC2879117
78: Kang HG, Jenabi JM, Liu XF, Reynolds CP, Triche TJ, Sorensen PH
Inhibition of the insulin-like growth factor I receptor by epigallocatechin gallate blocks proliferation and induces the death of Ewing tumor cells.
Mol Cancer Ther 9: 1396-407 (2010)
PM ID: 20423994
79: Cheng Z, De Jesus OP, Kramer DJ, De A, Webster JM, Gheysens O, Levi J, Namavari M, Wang S, Park JM, Zhang R, Liu H, Lee B, Syud FA, Gambhir SS
64Cu-labeled affibody molecules for imaging of HER2 expressing tumors.
Mol Imaging Biol 12: 316-24 (2010)
PM ID: 19779897
80: Jao CC, Hegde BG, Gallop JL, Hegde PB, McMahon HT, Haworth IS, Langen R
Roles of amphipathic helices and the bin/amphiphysin/rvs (BAR) domain of endophilin in membrane curvature generation.
J Biol Chem 285: 20164-70 (2010)
PM ID: 20418375 PMC2888429
81: Horton TM, Sposto R, Brown P, Reynolds CP, Hunger SP, Winick NJ, Raetz EA, Carroll WL, Arceci RJ, Borowitz MJ, Gaynon PS, Gore L, Jeha S, Maurer BJ, Siegel SE, Biondi A, Kearns PR, Narendran A, Silverman LB, Smith MA, Zwaan CM, Whitlock JA, ALLNA 2008 Conference
Toxicity assessment of molecularly targeted drugs incorporated into multiagent chemotherapy regimens for pediatric acute lymphocytic leukemia (ALL): review from an international consensus conference.
Pediatr Blood Cancer 54: 872-8 (2010)
PM ID: 20127846 PMC2857540 NIHMS163748
82: Khatua S, Dhall G, O'Neil S, Jubran R, Villablanca JG, Marachelian A, Nastia A, Lavey R, Olch AJ, Gonzalez I, Gilles F, Nelson M, Panigrahy A, McComb G, Krieger M, Fan J, Sposto R, Finlay JL
Treatment of primary CNS germinomatous germ cell tumors with chemotherapy prior to reduced dose whole ventricular and local boost irradiation.
Pediatr Blood Cancer 55: 42-6 (2010)
PM ID: 20222020
83: Moreno L, Pollack IF, Duffner PK, Geyer JR, Grill J, Massimino M, Finlay JL, Zacharoulis S
Utility of cerebrospinal fluid cytology in newly diagnosed childhood ependymoma.
J Pediatr Hematol Oncol 32: 515-8 (2010)
PM ID: 20463607
84: Holt N, Wang J, Kim K, Friedman G, Wang X, Taupin V, Crooks GM, Kohn DB, Gregory PD, Holmes MC, Cannon PM
Human hematopoietic stem/progenitor cells modified by zinc-finger nucleases targeted to CCR5 control HIV-1 in vivo.
Nat Biotechnol 28: 839-47 (2010)
PM ID: 20601939 PMC3080757 NIHMS216984
85: Souweidane MM, Krieger MD, Weiner HL, Finlay JL
Surgical management of primary central nervous system germ cell tumors: proceedings from the Second International Symposium on Central Nervous System Germ Cell Tumors.
J Neurosurg Pediatr 6: 125-30 (2010)
PM ID: 20672932
86: Hoffmann AC, Wild P, Leicht C, Bertz S, Danenberg KD, Danenberg PV, Stöhr R, Stöckle M, Lehmann J, Schuler M, Hartmann A
MDR1 and ERCC1 expression predict outcome of patients with locally advanced bladder cancer receiving adjuvant chemotherapy.
Neoplasia 12: 628-36 (2010)
PM ID: 20689757 PMC2915407
87: Yu AL, Gilman AL, Ozkaynak MF, London WB, Kreissman SG, Chen HX, Smith M, Anderson B, Villablanca JG, Matthay KK, Shimada H, Grupp SA, Seeger R, Reynolds CP, Buxton A, Reisfeld RA, Gillies SD, Cohn SL, Maris JM, Sondel PM, Children's Oncology Group
Anti-GD2 antibody with GM-CSF, interleukin-2, and isotretinoin for neuroblastoma.
N Engl J Med 363: 1324-34 (2010)
PM ID: 20879881 PMC3086629 NIHMS245842
88: Greenwood M, Salvi S, Kanwar V, Strother D, Frantz C, Daghistani D, Grewal S, Kretschmar C, Bond M, Mody R, Yanofsky R, Ferguson W, Atkinson M, McMahon D, Michon B, Yu L, Feusner J, Crouse V, Kuerbitz S, Halton J, Ravindranath Y, Broxson E, Dome J, Mascarenhas L, Shen V, Balis F, Lowe E, Bostrom B, Walterhouse D, Perentesis J, Tekautz T, Lee A, Isakoff M, Granger M, Prasannan L, Rodriguez-Galindo C, Chaffee S, Lockhart S, Johnson MC, Kreissman S, Pais R, Katzenstein H, Selsky C, Taylor J, Shad A, Stroud C, Appel B, Finklestein J, Dickens D, Samson Y, Grant R, Fallon R, Schorin M, Hand J, Arceci R, Kiley V, Lobel J, Silva M, Bertolone S, Salman E, Olson J, Bedros A, Kwon JH, Larsen E, McManus M, Louie R, Weinstein H, Arndt C, Portwine C, Lenarsky C, McDonough C, Kraveka J, Johnston J, Hanif I, Jasty R, Kobrinsky N, Estrada J, Gera R, Kelly M, Ricafort R, Chang E, Kirkpatrick G, Termuhlen A, Sandler E, Bernstein J, Ozkaynak M, Kamalakar P, Neely J, Boklan J, Bryant P, Barnette P, Cole C, Roberts W, Matloub YJ, Mitchell T, Schwartz C, Brecher M, Ashley D, Irving H, Felgenhauer J, Chatchawin A, Cameron T, John H, Bassem R, Luis C, Daniel G, Christopher M, Arlene R, Douglas H, Joseph W, Furman W, Smith S, Gowda N, Marina N, Desai SJ, Cherrick I, Lee Y, Ammann R, Beck Popovic M, Bomgaars L, Turner C, Maloney K, McCowage G, Hetherington M, Cohn S, Stein D, Scher C, Fu C, Drachtman R, Reddy A, Wittman B, Becton D, Goldsby R, Ducore J, Smith A, Schmidt M, Tannous R, Kumar M, York T, Keuker C, Neglia J, Megason G, Loew T, Winter S, Gold S, McNall-Knapp R, Ritchey A, Hackney L, Thomas P, Homans A, De Santes K, Winick N, Kuttesch J, Cairney A, Godder K, McLean T, Hayashi R, Chauvenet A, Main C, Weinblatt M, Kupfer G, Baker DL, Schmidt ML, Cohn SL, Maris JM, London WB, Buxton A, Stram D, Castleberry RP, Shimada H, Sandler A, Shamberger RC, Look AT, Reynolds CP, Seeger RC, Matthay KK, Children’s Oncology Group
Outcome after reduced chemotherapy for intermediate-risk neuroblastoma.
N Engl J Med 363: 1313-23 (2010)
PM ID: 20879880 PMC2993160 NIHMS246674
89: Beaty O, Berg S, Blaney S, Malogolowkin M, Krailo M, Knight R, Schaiquevich P, Stewart C, Chen Z, Nelson M, Voss S, Ivy SP, Adamson PC
A phase II trial and pharmacokinetic study of oxaliplatin in children with refractory solid tumors: a Children's Oncology Group study.
Pediatr Blood Cancer 55: 440-5 (2010)
PM ID: 20658614
90: Grimminger PP, Schneider PM, Metzger R, Vallböhmer D, Hölscher AH, Danenberg PV, Brabender J
Low thymidylate synthase, thymidine phosphorylase, and dihydropyrimidine dehydrogenase mRNA expression correlate with prolonged survival in resected non-small-cell lung cancer.
Clin Lung Cancer 11: 328-34 (2010)
PM ID: 20837458
91: Grimminger PP, Schneider PM, Metzger R, Vallböhmer D, Danenberg KD, Danenberg PV, Hölscher AH, Brabender J
The prognostic role of Bcl-2 mRNA expression in curatively resected non-small cell lung cancer (NSCLC).
Lung Cancer 70: 82-7 (2010)
PM ID: 20064672
92: Cai W, Maldonado NV, Cui W, Harutyunyan N, Ji L, Sposto R, Reynolds CP, Keshelava N
Activity of irinotecan and temozolomide in the presence of O6-methylguanine-DNA methyltransferase inhibition in neuroblastoma pre-clinical models.
Br J Cancer 103: 1369-79 (2010)
PM ID: 20924375 PMC2990610
93: Ramkumar K, Serrao E, Odde S, Neamati N
HIV-1 integrase inhibitors: 2007-2008 update.
Med Res Rev 30: 890-954 (2010)
PM ID: 20135632
94: Mori R, Dorff TB, Xiong S, Tarabolous CJ, Ye W, Groshen S, Danenberg KD, Danenberg PV, Pinski JK
The relationship between proangiogenic gene expression levels in prostate cancer and their prognostic value for clinical outcomes.
Prostate 70: 1692-700 (2010)
PM ID: 20564320
95: Shusterman S, London WB, Gillies SD, Hank JA, Voss SD, Seeger RC, Reynolds CP, Kimball J, Albertini MR, Wagner B, Gan J, Eickhoff J, DeSantes KB, Cohn SL, Hecht T, Gadbaw B, Reisfeld RA, Maris JM, Sondel PM
Antitumor activity of hu14.18-IL2 in patients with relapsed/refractory neuroblastoma: a Children's Oncology Group (COG) phase II study.
J Clin Oncol 28: 4969-75 (2010)
PM ID: 20921469 PMC3020698
96: Hadi V, Koh YH, Sanchez TW, Barrios D, Neamati N, Jung KW
Development of the next generation of HIV-1 integrase inhibitors: pyrazolone as a novel inhibitor scaffold.
Bioorg Med Chem Lett 20: 6854-7 (2010)
PM ID: 20864343 PMC2957562 NIHMS229647
97: Parekh C, Jubran R, Erdreich-Epstein A, Panigrahy A, Bluml S, Finlay J, Dhall G
Erratum to: Treatment of children with recurrent high grade gliomas with a bevacizumab containing regimen.
J Neurooncol : (2010)
PM ID: 21110216
98: Rutkowski S, von Hoff K, Emser A, Zwiener I, Pietsch T, Figarella-Branger D, Giangaspero F, Ellison DW, Garre ML, Biassoni V, Grundy RG, Finlay JL, Dhall G, Raquin MA, Grill J
Survival and prognostic factors of early childhood medulloblastoma: an international meta-analysis.
J Clin Oncol 28: 4961-8 (2010)
PM ID: 20940197
99: Chen HJ, Panigrahy A, Dhall G, Finlay JL, Nelson MD, Blüml S
Apparent diffusion and fractional anisotropy of diffuse intrinsic brain stem gliomas.
AJNR Am J Neuroradiol 31: 1879-85 (2010)
PM ID: 20595371
100: Bernstein I, Byun HM, Mohrbacher A, Douer D, Gorospe G, Hergesheimer J, Groshen S, O'Connell C, Yang AS
A phase I biological study of azacitidine (Vidaza™) to determine the optimal dose to inhibit DNA methylation.
Epigenetics 5: 750-7 (2010)
PM ID: 20861661
101: Pollack IF, Hamilton RL, Sobol RW, Nikiforova MN, Nikiforov YE, Lyons-Weiler MA, Laframboise WA, Burger PC, Brat DJ, Rosenblum MK, Gilles FH, Yates AJ, Zhou T, Cohen KJ, Finlay JL, Jakacki RI, Children's Oncology Group
Mismatch repair deficiency is an uncommon mechanism of alkylator resistance in pediatric malignant gliomas: a report from the Children's Oncology Group.
Pediatr Blood Cancer 55: 1066-71 (2010)
PM ID: 20589656 PMC3036982 NIHMS270263
102: Debnath B, Al-Mawsawi LQ, Neamati N
Are we living in the end of the blockbuster drug era?
Drug News Perspect 23: 670-84 (2010)
PM ID: 21180653
103: Dhall G, Khatua S, Finlay JL
Pineal region tumors in children.
Curr Opin Neurol 23: 576-82 (2010)
PM ID: 21042218
104: Venkatramani R, Ma NS, Pitukcheewanont P, Malogolowkin MH, Mascarenhas L
Gorham's disease and diffuse lymphangiomatosis in children and adolescents.
Pediatr Blood Cancer : (2010)
PM ID: 21181877
105: Gupta AA, Gerstle JT, Ng V, Wong A, Fecteau A, Malogolowkin MH, Meyers RL, Grant D, Grant RM
Critical review of controversial issues in the management of advanced pediatric liver tumors.
Pediatr Blood Cancer : (2010)
PM ID: 21125617
106: Gandara DR, Grimminger P, Mack PC, Lara PN, Li T, Danenberg PV, Danenberg KD
Association of epidermal growth factor receptor activating mutations with low ERCC1 gene expression in non-small cell lung cancer.
J Thorac Oncol 5: 1933-8 (2010)
PM ID: 20975603
107: Millard M, Pathania D, Grande F, Xu S, Neamati N
Small-molecule inhibitors of p53-MDM2 interaction: the 2006-2010 update.
Curr Pharm Des 17: 536-59 (2011)
PM ID: 21391905
108: Sands SA, Pasichow KP, Weiss R, Garvin J, Gardner S, Dunkel IJ, Finlay JL
Quality of life and behavioral follow-up study of Head Start I pediatric brain tumor survivors.
J Neurooncol 101: 287-95 (2011)
PM ID: 20526792
109: Grimminger CM, Danenberg PV
Update of prognostic and predictive biomarkers in oropharyngeal squamous cell carcinoma: a review.
Eur Arch Otorhinolaryngol 268: 5-16 (2011)
PM ID: 20827554
110: Al-Mawsawi LQ, Neamati N
Allosteric Inhibitor Development Targeting HIV-1 Integrase.
ChemMedChem : (2011)
PM ID: 21229520
111: Sun X, Yan Y, Liu S, Cao Q, Yang M, Neamati N, Shen B, Niu G, Chen X
18F-FPPRGD2 and 18F-FDG PET of response to Abraxane therapy.
J Nucl Med 52: 140-6 (2011)
PM ID: 21149494
112: Choi SH, Heo K, Byun HM, An W, Lu W, Yang AS
Identification of preferential target sites for human DNA methyltransferases.
Nucleic Acids Res 39: 104-18 (2011)
PM ID: 20841325 PMC3017615
113: Iqbal S, Tsao-Wei DD, Quinn DI, Gitlitz BJ, Groshen S, Aparicio A, Lenz HJ, El-Khoueiry A, Pinski J, Garcia AA
Phase I clinical trial of pegylated liposomal Doxorubicin and docetaxel in patients with advanced solid tumors.
Am J Clin Oncol 34: 27-31 (2011)
PM ID: 20142723
114: Al-Mawsawi LQ, Neamati N
Allosteric inhibitor development targeting HIV-1 integrase.
ChemMedChem 6: 228-41 (2011)
PM ID: 21275045 PMC3115487 NIHMS267684
115: Sharma H, Patil S, Sanchez TW, Neamati N, Schinazi RF, Buolamwini JK
Synthesis, biological evaluation and 3D-QSAR studies of 3-keto salicylic acid chalcones and related amides as novel HIV-1 integrase inhibitors.
Bioorg Med Chem 19: 2030-45 (2011)
PM ID: 21371895 PMC3866048 NIHMS272252
116: Stanford SM, Krishnamurthy D, Falk MD, Messina R, Debnath B, Li S, Liu T, Kazemi R, Dahl R, He Y, Yu X, Chan AC, Zhang ZY, Barrios AM, Woods VL, Neamati N, Bottini N
Discovery of a novel series of inhibitors of lymphoid tyrosine phosphatase with activity in human T cells.
J Med Chem 54: 1640-54 (2011)
PM ID: 21341673 PMC3086468 NIHMS276264
117: Yamada R, Cao X, Butkevich AN, Millard M, Odde S, Mordwinkin N, Gundla R, Zandi E, Louie SG, Petasis NA, Neamati N
Discovery and preclinical evaluation of a novel class of cytotoxic propynoic acid carbamoyl methyl amides (PACMAs).
J Med Chem 54: 2902-14 (2011)
PM ID: 21443194
118: Bacchi A, Carcelli M, Compari C, Fisicaro E, Pala N, Rispoli G, Rogolino D, Sanchez TW, Sechi M, Neamati N
HIV-1 IN strand transfer chelating inhibitors: a focus on metal binding.
Mol Pharm 8: 507-19 (2011)
PM ID: 21323359
119: Venkatramani R, Ma NS, Pitukcheewanont P, Malogolowkin MH, Mascarenhas L
Gorham's disease and diffuse lymphangiomatosis in children and adolescents.
Pediatr Blood Cancer 56: 667-70 (2011)
PM ID: 21298758
120: Khatua S, Phillips A, Fangusaro J, Bovan S, Dhall G, Finlay JL
Recurrent pure CNS germinoma with markedly elevated serum and cerebrospinal fluid human chorionic gonadotropin-beta (HCGβ).
Pediatr Blood Cancer 56: 863-4 (2011)
PM ID: 20949592
121: Grimminger PP, Danenberg P, Dellas K, Arnold D, Rödel C, Machiels JP, Haustermans K, Debucquoy A, Velenik V, Sempoux C, Bracko M, Hölscher AH, Semrau R, Yang D, Danenberg K, Lenz HJ, Vallböhmer D
Biomarkers for cetuximab-based neoadjuvant radiochemotherapy in locally advanced rectal cancer.
Clin Cancer Res 17: 3469-77 (2011)
PM ID: 21558395
122: Villani A, Tabori U, Schiffman J, Shlien A, Beyene J, Druker H, Novokmet A, Finlay J, Malkin D
Biochemical and imaging surveillance in germline TP53 mutation carriers with Li-Fraumeni syndrome: a prospective observational study.
Lancet Oncol 12: 559-67 (2011)
PM ID: 21601526
123: Dhall G, Traverso M, Finlay JL, Shane L, Gonzalez-Gomez I, Jubran R
The role of chemotherapy in pediatric clival chordomas.
J Neurooncol 103: 657-62 (2011)
PM ID: 21052774
124: Parekh C, Jubran R, Erdreich-Epstein A, Panigrahy A, Bluml S, Finlay J, Dhall G
Treatment of children with recurrent high grade gliomas with a bevacizumab containing regimen.
J Neurooncol 103: 673-80 (2011)
PM ID: 21038110
125: Gupta AA, Gerstle JT, Ng V, Wong A, Fecteau A, Malogolowkin MH, Meyers RL, Grant D, Grant RM
Critical review of controversial issues in the management of advanced pediatric liver tumors.
Pediatr Blood Cancer 56: 1013-8 (2011)
PM ID: 21488153
126: Wu Z, Todorov I, Li L, Bading JR, Li Z, Nair I, Ishiyama K, Colcher D, Conti PE, Fraser SE, Shively JE, Kandeel F
In vivo imaging of transplanted islets with 64Cu-DO3A-VS-Cys40-Exendin-4 by targeting GLP-1 receptor.
Bioconjug Chem 22: 1587-94 (2011)
PM ID: 21692471
127: Malogolowkin MH, Katzenstein HM, Meyers RL, Krailo MD, Rowland JM, Haas J, Finegold MJ
Complete surgical resection is curative for children with hepatoblastoma with pure fetal histology: a report from the Children's Oncology Group.
J Clin Oncol 29: 3301-6 (2011)
PM ID: 21768450 PMC3158601
128: Fan X, Zhang FH, Al-Safi RI, Zeng LF, Shabaik Y, Debnath B, Sanchez TW, Odde S, Neamati N, Long YQ
Design of HIV-1 integrase inhibitors targeting the catalytic domain as well as its interaction with LEDGF/p75: a scaffold hopping approach using salicylate and catechol groups.
Bioorg Med Chem 19: 4935-52 (2011)
PM ID: 21778063 PMC3163123 NIHMS308124
129: Birkhahn M, Penson DF, Cai J, Groshen S, Stein JP, Lieskovsky G, Skinner DG, Cote RJ
Long-term outcome in patients with a Gleason score ≤ 6 prostate cancer treated by radical prostatectomy.
BJU Int 108: 660-4 (2011)
PM ID: 21223479
130: O'Neil S, Ji L, Buranahirun C, Azoff J, Dhall G, Khatua S, Patel S, Panigrahy A, Borchert M, Sposto R, Finlay J
Neurocognitive outcomes in pediatric and adolescent patients with central nervous system germinoma treated with a strategy of chemotherapy followed by reduced-dose and volume irradiation.
Pediatr Blood Cancer 57: 669-73 (2011)
PM ID: 21495164
131: Monserrat JP, Al-Safi RI, Tiwari KN, Quentin L, Chabot GG, Vessières A, Jaouen G, Neamati N, Hillard EA
Ferrocenyl chalcone difluoridoborates inhibit HIV-1 integrase and display low activity towards cancer and endothelial cells.
Bioorg Med Chem Lett 21: 6195-7 (2011)
PM ID: 21889342
132: Blüml S, Panigrahy A, Laskov M, Dhall G, Krieger MD, Nelson MD, Finlay JL, Gilles FH
Elevated citrate in pediatric astrocytomas with malignant progression.
Neuro Oncol 13: 1107-17 (2011)
PM ID: 21771868 PMC3177657
133: Fang H, Harned TM, Kalous O, Maldonado V, Declerck YA, Reynolds CP
Synergistic activity of fenretinide and the Bcl-2 family protein inhibitor ABT-737 against human neuroblastoma.
Clin Cancer Res 17: 7093-104 (2011)
PM ID: 21933888
134: Villablanca JG, London WB, Naranjo A, McGrady P, Ames MM, Reid JM, McGovern RM, Buhrow SA, Jackson H, Stranzinger E, Kitchen BJ, Sondel PM, Parisi MT, Shulkin B, Yanik GA, Cohn SL, Reynolds CP
Phase II study of oral capsular 4-hydroxyphenylretinamide (4-HPR/fenretinide) in pediatric patients with refractory or recurrent neuroblastoma: a report from the Children's Oncology Group.
Clin Cancer Res 17: 6858-66 (2011)
PM ID: 21908574 PMC3207022 NIHMS322852
135: Bacchi A, Carcelli M, Compari C, Fisicaro E, Pala N, Rispoli G, Rogolino D, Sanchez TW, Sechi M, Sinisi V, Neamati N
Investigating the role of metal chelation in HIV-1 integrase strand transfer inhibitors.
J Med Chem 54: 8407-20 (2011)
PM ID: 22066494
136: Malogolowkin MH, Katzenstein HM, Krailo M, Meyers RL
Treatment of hepatoblastoma: the North American cooperative group experience.
Front Biosci (Elite Ed) 4: 1717-23 (2012)
PM ID: 22201987
137: Serrao E, Thys W, Demeulemeester J, Al-Mawsawi LQ, Christ F, Debyser Z, Neamati N
A symmetric region of the HIV-1 integrase dimerization interface is essential for viral replication.
PLoS One 7: e45177 (2012)
PM ID: 23028829 PMC3445459
138: Tippin BL, Levine AJ, Materi AM, Song WL, Keku TO, Goodman JE, Sansbury LB, Das S, Dai A, Kwong AM, Lin AM, Lin JM, Park JM, Patterson RE, Chlebowski RT, Garavito RM, Inoue T, Cho W, Lawson JA, Kapoor S, Kolonel LN, Le Marchand L, Haile RW, Sandler RS, Lin HJ
Hematopoietic prostaglandin D synthase (HPGDS): a high stability, Val187Ile isoenzyme common among African Americans and its relationship to risk for colorectal cancer.
Prostaglandins Other Lipid Mediat 97: 22-8 (2012)
PM ID: 21821144 PMC3226866 NIHMS319011
139: Al-Safi RI, Odde S, Shabaik Y, Neamati N
Small-molecule inhibitors of APE1 DNA repair function: an overview.
Curr Mol Pharmacol 5: 14-35 (2012)
PM ID: 22122462
140: Yadav MR, Grande F, Chouhan BS, Naik PP, Giridhar R, Garofalo A, Neamati N
Cytotoxic potential of novel 6,7-dimethoxyquinazolines.
Eur J Med Chem 48: 231-43 (2012)
PM ID: 22209417
141: Cao B, Wang Y, Ding K, Neamati N, Long YQ
Synthesis of the pyridinyl analogues of dibenzylideneacetone (pyr-dba) via an improved Claisen-Schmidt condensation, displaying diverse biological activities as curcumin analogues.
Org Biomol Chem 10: 1239-45 (2012)
PM ID: 22179573
142: Zhang X, Tung CS, Sowa GZ, Hatmal MM, Haworth IS, Qin PZ
Global structure of a three-way junction in a phi29 packaging RNA dimer determined using site-directed spin labeling.
J Am Chem Soc 134: 2644-52 (2012)
PM ID: 22229766 PMC3279945 NIHMS353713
143: Venkatramani R, Dhall G, Patel M, Grimm J, Hawkins C, McComb G, Krieger M, Wong K, O'Neil S, Finlay JL
Supratentorial ependymoma in children: to observe or to treat following gross total resection?
Pediatr Blood Cancer 58: 380-3 (2012)
PM ID: 21370439
144: Sands SA, Zhou T, O'Neil SH, Patel SK, Allen J, McGuire Cullen P, Kaleita TA, Noll R, Sklar C, Finlay JL
Long-term follow-up of children treated for high-grade gliomas: children's oncology group L991 final study report.
J Clin Oncol 30: 943-9 (2012)
PM ID: 22355055 PMC3341107
145: Xu J, Erdreich-Epstein A, Gonzalez-Gomez I, Melendez EY, Smbatyan G, Moats RA, Rosol M, Biegel JA, Reynolds CP
Novel cell lines established from pediatric brain tumors.
J Neurooncol 107: 269-80 (2012)
PM ID: 22120608 PMC3379550 NIHMS380597
146: Gilsanz V, Hu HH, Smith ML, Goodarzian F, Carcich SL, Warburton NM, Malogolowkin M
The depiction of brown adipose tissue is related to disease status in pediatric patients with lymphoma.
AJR Am J Roentgenol 198: 909-13 (2012)
PM ID: 22451560
147: Strother DR, London WB, Schmidt ML, Brodeur GM, Shimada H, Thorner P, Collins MH, Tagge E, Adkins S, Reynolds CP, Murray K, Lavey RS, Matthay KK, Castleberry R, Maris JM, Cohn SL
Outcome after surgery alone or with restricted use of chemotherapy for patients with low-risk neuroblastoma: results of Children's Oncology Group study P9641.
J Clin Oncol 30: 1842-8 (2012)
PM ID: 22529259 PMC3383182
148: Gozali AE, Britt B, Shane L, Gonzalez I, Gilles F, McComb JG, Krieger MD, Lavey RS, Shlien A, Villablanca JG, Erdreich-Epstein A, Dhall G, Jubran R, Tabori U, Malkin D, Finlay JL
Choroid plexus tumors; management, outcome, and association with the Li-Fraumeni syndrome: the Children's Hospital Los Angeles (CHLA) experience, 1991-2010.
Pediatr Blood Cancer 58: 905-9 (2012)
PM ID: 21990040
149: Orgel E, Jain S, Ji L, Pollick L, Si S, Finlay J, Freyer DR
Hearing loss among survivors of childhood brain tumors treated with an irradiation-sparing approach.
Pediatr Blood Cancer 58: 953-8 (2012)
PM ID: 21796767
150: Puumala SE, Ross JA, Feusner JH, Tomlinson GE, Malogolowkin MH, Krailo MD, Spector LG
Parental infertility, infertility treatment and hepatoblastoma: a report from the Children's Oncology Group.
Hum Reprod 27: 1649-56 (2012)
PM ID: 22473396 PMC3357199
151: Popova AM, Hatmal MM, Frushicheva MP, Price EA, Qin PZ, Haworth IS
Nitroxide sensing of a DNA microenvironment: mechanistic insights from EPR spectroscopy and molecular dynamics simulations.
J Phys Chem B 116: 6387-96 (2012)
PM ID: 22574834 PMC3382087 NIHMS377685
152: Ng TS, Bading JR, Park R, Sohi H, Procissi D, Colcher D, Conti PS, Cherry SR, Raubitschek AA, Jacobs RE
Quantitative, simultaneous PET/MRI for intratumoral imaging with an MRI-compatible PET scanner.
J Nucl Med 53: 1102-9 (2012)
PM ID: 22661534 PMC3552656 NIHMS399293
153: Venkatramani R, Malogolowkin MH, Wang L, Mascarenhas L
Pleuropulmonary blastoma: a single-institution experience.
J Pediatr Hematol Oncol 34: e182-5 (2012)
PM ID: 22584785
154: Bonnin A, Zhang L, Blakely RD, Levitt P
The SSRI citalopram affects fetal thalamic axon responsiveness to netrin-1 in vitro independently of SERT antagonism.
Neuropsychopharmacology 37: 1879-84 (2012)
PM ID: 22414815 PMC3376320
155: Debnath B, Xu S, Neamati N
Small molecule inhibitors of signal transducer and activator of transcription 3 (Stat3) protein.
J Med Chem 55: 6645-68 (2012)
PM ID: 22650325
156: Venkatramani R, Furman WL, Fuchs J, Warmann SW, Malogolowkin MH
Current and future management strategies for relapsed or progressive hepatoblastoma.
Paediatr Drugs 14: 221-32 (2012)
PM ID: 22702740
157: Venkatramani R, Wang L, Malvar J, Dias D, Sposto R, Malogolowkin MH, Mascarenhas L
Tumor necrosis predicts survival following neo-adjuvant chemotherapy for hepatoblastoma.
Pediatr Blood Cancer 59: 493-8 (2012)
PM ID: 22190448
158: Rudie JD, Hernandez LM, Brown JA, Beck-Pancer D, Colich NL, Gorrindo P, Thompson PM, Geschwind DH, Bookheimer SY, Levitt P, Dapretto M
Autism-associated promoter variant in MET impacts functional and structural brain networks.
Neuron 75: 904-15 (2012)
PM ID: 22958829 PMC3454529 NIHMS403140
159: Grimminger PP, Shi M, Barrett C, Lebwohl D, Danenberg KD, Brabender J, Vigen CL, Danenberg PV, Winder T, Lenz HJ
TS and ERCC-1 mRNA expressions and clinical outcome in patients with metastatic colon cancer in CONFIRM-1 and -2 clinical trials.
Pharmacogenomics J 12: 404-11 (2012)
PM ID: 21788964
160: Yu S, Zhang L, Yan S, Wang P, Sanchez T, Christ F, Debyser Z, Neamati N, Zhao G
Nitrogen-containing polyhydroxylated aromatics as HIV-1 integrase inhibitors: synthesis, structure-activity relationship analysis, and biological activity.
J Enzyme Inhib Med Chem 27: 628-40 (2012)
PM ID: 22233539
161: Hammock EA, Levitt P
Modulation of parvalbumin interneuron number by developmentally transient neocortical vasopressin receptor 1a (V1aR).
Neuroscience 222: 20-8 (2012)
PM ID: 22820266 PMC3444161 NIHMS395738
162: Grimminger PP, Maus MK, Schneider PM, Metzger R, Hölscher AH, Sugita H, Danenberg PV, Alakus H, Brabender J
Glutathione S-transferase PI (GST-PI) mRNA expression and DNA methylation is involved in the pathogenesis and prognosis of NSCLC.
Lung Cancer 78: 87-91 (2012)
PM ID: 22884253
163: Xu S, Butkevich AN, Yamada R, Zhou Y, Debnath B, Duncan R, Zandi E, Petasis NA, Neamati N
Discovery of an orally active small-molecule irreversible inhibitor of protein disulfide isomerase for ovarian cancer treatment.
Proc Natl Acad Sci U S A 109: 16348-53 (2012)
PM ID: 22988091 PMC3479552
164: Aiello F, Shabaik Y, Esqueda A, Sanchez TW, Grande F, Garofalo A, Neamati N
Design and synthesis of 3-carbamoylbenzoic acid derivatives as inhibitors of human apurinic/apyrimidinic endonuclease 1 (APE1).
ChemMedChem 7: 1825-39 (2012)
PM ID: 22952012
165: Wang Z, Huang P, Bhirde A, Jin A, Ma Y, Niu G, Neamati N, Chen X
A nanoscale graphene oxide-peptide biosensor for real-time specific biomarker detection on the cell surface.
Chem Commun (Camb) 48: 9768-70 (2012)
PM ID: 22919703 PMC3622590 NIHMS455060
166: Perilongo G, Malogolowkin M, Feusner J
Hepatoblastoma clinical research: lessons learned and future challenges.
Pediatr Blood Cancer 59: 818-21 (2012)
PM ID: 22678761
167: Zeng LF, Wang Y, Kazemi R, Xu S, Xu ZL, Sanchez TW, Yang LM, Debnath B, Odde S, Xie H, Zheng YT, Ding J, Neamati N, Long YQ
Repositioning HIV-1 integrase inhibitors for cancer therapeutics: 1,6-naphthyridine-7-carboxamide as a promising scaffold with drug-like properties.
J Med Chem 55: 9492-509 (2012)
PM ID: 23098137
168: Termuhlen AM, Smith LM, Perkins SL, Lones M, Finlay JL, Weinstein H, Gross TG, Abromowitch M
Outcome of newly diagnosed children and adolescents with localized lymphoblastic lymphoma treated on Children's Oncology Group trial A5971: a report from the Children's Oncology Group.
Pediatr Blood Cancer 59: 1229-33 (2012)
PM ID: 22488718
169: Garvin JH, Selch MT, Holmes E, Berger MS, Finlay JL, Flannery A, Goldwein JW, Packer RJ, Rorke-Adams LB, Shiminski-Maher T, Sposto R, Stanley P, Tannous R, Pollack IF, Children's Oncology Group
Phase II study of pre-irradiation chemotherapy for childhood intracranial ependymoma. Children's Cancer Group protocol 9942: a report from the Children's Oncology Group.
Pediatr Blood Cancer 59: 1183-9 (2012)
PM ID: 22949057
170: Aboye TL, Ha H, Majumder S, Christ F, Debyser Z, Shekhtman A, Neamati N, Camarero JA
Design of a novel cyclotide-based CXCR4 antagonist with anti-human immunodeficiency virus (HIV)-1 activity.
J Med Chem 55: 10729-34 (2012)
PM ID: 23151033 PMC3521869 NIHMS422450
171: Debnath B, Xu S, Grande F, Garofalo A, Neamati N
Small molecule inhibitors of CXCR4.
Theranostics 3: 47-75 (2013)
PM ID: 23382786 PMC3563081
172: Shabaik YH, Millard M, Neamati N
Mechanistic evaluation of a novel small molecule targeting mitochondria in pancreatic cancer cells.
PLoS One 8: e54346 (2013)
PM ID: 23349858 PMC3549929
173: Venkatramani R, Malogolowkin M, Davidson TB, May W, Sposto R, Mascarenhas L
A phase I study of vincristine, irinotecan, temozolomide and bevacizumab (vitb) in pediatric patients with relapsed solid tumors.
PLoS One 8: e68416 (2013)
PM ID: 23894304 PMC3718768
174: Ha TC, Spreafico F, Graf N, Dallorso S, Dome JS, Malogolowkin M, Furtwängler R, Hale JP, Moroz V, Machin D, Pritchard-Jones K
An international strategy to determine the role of high dose therapy in recurrent Wilms' tumour.
Eur J Cancer 49: 194-210 (2013)
PM ID: 22959164
175: Carcelli M, Bacchi A, Pelagatti P, Rispoli G, Rogolino D, Sanchez TW, Sechi M, Neamati N
Ruthenium arene complexes as HIV-1 integrase strand transfer inhibitors.
J Inorg Biochem 118: 74-82 (2013)
PM ID: 23123342
176: Torii M, Rakic P, Levitt P
Role of EphA/ephrin--a signaling in the development of topographic maps in mouse corticothalamic projections.
J Comp Neurol 521: 626-37 (2013)
PM ID: 22821544 PMC3511615 NIHMS395732
177: Baskin JL, Lezcano E, Kim BS, Figueredo D, Lassaletta A, Perez-Martinez A, Madero L, Caniza MA, Howard SC, Samudio A, Finlay JL
Management of children with brain tumors in Paraguay.
Neuro Oncol 15: 235-41 (2013)
PM ID: 23197688 PMC3548583
178: Sanchez TW, Debnath B, Christ F, Otake H, Debyser Z, Neamati N
Discovery of novel inhibitors of LEDGF/p75-IN protein-protein interactions.
Bioorg Med Chem 21: 957-63 (2013)
PM ID: 23306052
179: Mitra AP, Castelao JE, Hawes D, Tsao-Wei DD, Jiang X, Shi SR, Datar RH, Skinner EC, Stein JP, Groshen S, Yu MC, Ross RK, Skinner DG, Cortessis VK, Cote RJ
Combination of molecular alterations and smoking intensity predicts bladder cancer outcome: a report from the Los Angeles Cancer Surveillance Program.
Cancer 119: 756-65 (2013)
PM ID: 23319010 PMC3565093 NIHMS393599
180: Hsieh YT, Gang EJ, Geng H, Park E, Huantes S, Chudziak D, Dauber K, Schaefer P, Scharman C, Shimada H, Shojaee S, Klemm L, Parameswaran R, Loh M, Kang ES, Koo HH, Hofmann WK, Andrade J, Crooks GM, Willman CL, Müschen M, Papayannopoulou T, Heisterkamp N, Bönig H, Kim YM
Integrin alpha4 blockade sensitizes drug resistant pre-B acute lymphoblastic leukemia to chemotherapy.
Blood 121: 1814-8 (2013)
PM ID: 23319569 PMC3591800
181: Torii M, Hackett TA, Rakic P, Levitt P, Polley DB
EphA signaling impacts development of topographic connectivity in auditory corticofugal systems.
Cereb Cortex 23: 775-85 (2013)
PM ID: 22490549 PMC3593572
182: Parekh C, Crooks GM
Critical differences in hematopoiesis and lymphoid development between humans and mice.
J Clin Immunol 33: 711-5 (2013)
PM ID: 23274800 PMC3633618 NIHMS432026
183: Rodriguez-Galindo C, Krailo M, Frazier L, Chintagumpala M, Amatruda J, Katzenstein H, Malogolowkin M, Spector L, Pashankar F, Meyers R, Tomlinson G, COG Rare Tumors Disease Committee
Children's Oncology Group's 2013 blueprint for research: rare tumors.
Pediatr Blood Cancer 60: 1016-21 (2013)
PM ID: 23255219
184: Venkatramani R, Ji L, Lasky J, Haley K, Judkins A, Zhou S, Sposto R, Olshefski R, Garvin J, Tekautz T, Kennedy G, Rassekh SR, Moore T, Gardner S, Allen J, Shore R, Moertel C, Atlas M, Dhall G, Finlay J
Outcome of infants and young children with newly diagnosed ependymoma treated on the "Head Start" III prospective clinical trial.
J Neurooncol 113: 285-91 (2013)
PM ID: 23508296
185: Mascarenhas L, Malogolowkin M, Armenian SH, Sposto R, Venkatramani R
A phase I study of oxaliplatin and doxorubicin in pediatric patients with relapsed or refractory extracranial non-hematopoietic solid tumors.
Pediatr Blood Cancer 60: 1103-7 (2013)
PM ID: 23335436 PMC3815656 NIHMS519900
186: Law MJ, Lee DS, Lee CS, Anglim PP, Haworth IS, Laird-Offringa IA
The role of the C-terminal helix of U1A protein in the interaction with U1hpII RNA.
Nucleic Acids Res 41: 7092-100 (2013)
PM ID: 23703211 PMC3737524
187: Ji Y, Majumder S, Millard M, Borra R, Bi T, Elnagar AY, Neamati N, Shekhtman A, Camarero JA
In vivo activation of the p53 tumor suppressor pathway by an engineered cyclotide.
J Am Chem Soc 135: 11623-33 (2013)
PM ID: 23848581 PMC3767463 NIHMS510093
188: Kreissman SG, Seeger RC, Matthay KK, London WB, Sposto R, Grupp SA, Haas-Kogan DA, LaQuaglia MP, Yu AL, Diller L, Buxton A, Park JR, Cohn SL, Maris JM, Reynolds CP, Villablanca JG
Purged versus non-purged peripheral blood stem-cell transplantation for high-risk neuroblastoma (COG A3973): a randomised phase 3 trial.
Lancet Oncol 14: 999-1008 (2013)
PM ID: 23890779 PMC3963485 NIHMS540046
189: Wilson PM, Yang D, Azuma M, Shi MM, Danenberg KD, Lebwohl D, Sherrod A, Ladner RD, Zhang W, Danenberg PV, Trarbach T, Folprecht G, Meinhardt G, Lenz HJ
Intratumoral expression profiling of genes involved in angiogenesis in colorectal cancer patients treated with chemotherapy plus the VEGFR inhibitor PTK787/ZK 222584 (vatalanib).
Pharmacogenomics J 13: 410-6 (2013)
PM ID: 22664478
190: Malogolowkin MH, Krailo M, Marina N, Olson T, Frazier AL
Pilot study of cisplatin, etoposide, bleomycin, and escalating dose cyclophosphamide therapy for children with high risk germ cell tumors: a report of the children's oncology group (COG).
Pediatr Blood Cancer 60: 1602-5 (2013)
PM ID: 23703725
191: Maurer BJ, Kang MH, Villablanca JG, Janeba J, Groshen S, Matthay KK, Sondel PM, Maris JM, Jackson HA, Goodarzian F, Shimada H, Czarnecki S, Hasenauer B, Reynolds CP, Marachelian A
Phase I trial of fenretinide delivered orally in a novel organized lipid complex in patients with relapsed/refractory neuroblastoma: a report from the New Approaches to Neuroblastoma Therapy (NANT) consortium.
Pediatr Blood Cancer 60: 1801-8 (2013)
PM ID: 23813912 PMC4066886 NIHMS572867
192: Zaky W, Dhall G, Ji L, Haley K, Allen J, Atlas M, Bertolone S, Cornelius A, Gardner S, Patel R, Pradhan K, Shen V, Thompson S, Torkildson J, Sposto R, Finlay JL
Intensive induction chemotherapy followed by myeloablative chemotherapy with autologous hematopoietic progenitor cell rescue for young children newly-diagnosed with central nervous system atypical teratoid/rhabdoid tumors: the Head Start III experience.
Pediatr Blood Cancer 61: 95-101 (2014)
PM ID: 23934933
193: Venkatramani R, Malogolowkin MH, Mascarenhas L
Treatment of multiply relapsed wilms tumor with vincristine, irinotecan, temozolomide and bevacizumab.
Pediatr Blood Cancer 61: 756-9 (2014)
PM ID: 24115645