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USC Norris Comprehensive Cancer Center
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Publications for Norris Cancer Center Members in the Developmental Therapeutics Program

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  • Authors who are Program members appear in bold.
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Total Number of Publications: 280
Inter Programmatic Publications: 111
Intra Programmatic Publications: 4

1: Banki F, Mason RJ, Hagen JA, DeMeester SR, Lipham JC, Danenberg K, Danenberg P, DeMeester TR
Plasma DNA: a molecular marker of surgical insult and postoperative recovery in esophageal cancer.
Eur Surg Res 40: 273-8 (2008)
PM ID: 18219202
2: Grande F, Garofalo A, Neamati N
Small molecules anti-HIV therapeutics targeting CXCR4.
Curr Pharm Des 14: 385-404 (2008)
PM ID: 18289065
3: Theisen J, Danenberg K, Ott K, Becker K, Danenberg P, Stein HJ, Siewert JR
Predictors of response and survival for neoadjuvant treated patients with esophageal adenocarcinoma.
Dis Esophagus 21: 601-6 (2008)
PM ID: 18430179
4: Gutschow CA, Vallböhmer D, Stolte M, Oh D, Danenberg K, Danenberg P, Schneider PM, Hölscher AH
Adenocarcinoma developing in de novo Barrett's mucosa in the remnant esophagus after esophagectomy: clinical and molecular assessment.
Dis Esophagus 21: E6-8 (2008)
PM ID: 18430096
5: Makino H, Uetake H, Danenberg K, Danenberg PV, Sugihara K
Efficacy of laser capture microdissection plus RT-PCR technique in analyzing gene expression levels in human gastric cancer and colon cancer.
BMC Cancer 8: 210 (2008)
PM ID: 18652704 PMC2533342
6: Sechi M, Azzena U, Delussu MP, Dallocchio R, Dessì A, Cosseddu A, Pala N, Neamati N
Design and synthesis of bis-amide and hydrazide-containing derivatives of malonic acid as potential HIV-1 integrase inhibitors.
Molecules 13: 2442-61 (2008)
PM ID: 18830166
7: Uchida K, Danenberg PV, Danenberg KD, Grem JL
Thymidylate synthase, dihydropyrimidine dehydrogenase, ERCC1, and thymidine phosphorylase gene expression in primary and metastatic gastrointestinal adenocarcinoma tissue in patients treated on a phase I trial of oxaliplatin and capecitabine.
BMC Cancer 8: 386 (2008)
PM ID: 19105824 PMC2637882
8: Kohn DB
Gene therapy for childhood immunological diseases.
Bone Marrow Transplant 41: 199-205 (2008)
PM ID: 17994122
9: Taylor JA, Vojtech L, Bahner I, Kohn DB, Laer DV, Russell DW, Richard RE
Foamy virus vectors expressing anti-HIV transgenes efficiently block HIV-1 replication.
Mol Ther 16: 46-51 (2008)
PM ID: 17955023
10: Conti PS, Bading JR, Mouton PP, Links JM, Alauddin MM, Fissekis JD, Ravert HT, Hilton J, Wong DF, Anderson JH
In vivo measurement of cell proliferation in canine brain tumor using C-11-labeled FMAU and PET.
Nucl Med Biol 35: 131-41 (2008)
PM ID: 18158952
11: Dhall G, Finlay JL, Dunkel IJ, Ettinger LJ, Kellie SJ, Allen JC, Egeler RM, Arceci RJ
Analysis of outcome for patients with mass lesions of the central nervous system due to Langerhans cell histiocytosis treated with 2-chlorodeoxyadenosine.
Pediatr Blood Cancer 50: 72-9 (2008)
PM ID: 17455311
12: Marachelian A, Butturini A, Finlay J
Myeloablative chemotherapy with autologous hematopoietic progenitor cell rescue for childhood central nervous system tumors.
Bone Marrow Transplant 41: 167-72 (2008)
PM ID: 18176620
13: Mori R, Wang Q, Quek ML, Tarabolous C, Cheung E, Ye W, Groshen S, Hawes D, Togo S, Shimada H, Danenberg KD, Danenberg PV, Pinski JK
Prognostic value of the androgen receptor and its coactivators in patients with D1 prostate cancer.
Anticancer Res 28: 425-30 (2008)
PM ID: 18383880
14: Bonde J, Wirthlin L, Kohn DB, Nolta JA
Human hematopoietic cell culture, transduction, and analyses.
Curr Protoc Hum Genet Chapter 13: Unit 13.7 (2008)
PM ID: 18428422
15: Shariat SF, Karakiewicz PI, Ashfaq R, Lerner SP, Palapattu GS, Cote RJ, Sagalowsky AI, Lotan Y
Multiple biomarkers improve prediction of bladder cancer recurrence and mortality in patients undergoing cystectomy.
Cancer 112: 315-25 (2008)
PM ID: 18008359
16: Harned TM, Kalous O, Neuwelt A, Loera J, Ji L, Iovine P, Sposto R, Neuwelt EA, Reynolds CP
Sodium thiosulfate administered six hours after cisplatin does not compromise antineuroblastoma activity.
Clin Cancer Res 14: 533-40 (2008)
PM ID: 18223229
17: Houghton PJ, Morton CL, Kolb EA, Lock R, Carol H, Reynolds CP, Keshelava N, Maris JM, Keir ST, Wu J, Smith MA
Initial testing (stage 1) of the proteasome inhibitor bortezomib by the pediatric preclinical testing program.
Pediatr Blood Cancer 50: 37-45 (2008)
PM ID: 17420992
18: Dayam R, Gundla R, Al-Mawsawi LQ, Neamati N
HIV-1 integrase inhibitors: 2005-2006 update.
Med Res Rev 28: 118-54 (2008)
PM ID: 17979144
19: Kuramochi H, Tanaka K, Oh D, Lehman BJ, Dunst CM, Yang DY, De Meester SR, Hagen JA, Danenberg KD, De Meester TR, Danenberg PV
Thymidylate synthase polymorphisms and mRNA expression are independent chemotherapy predictive markers in esophageal adenocarcinoma patients.
Int J Oncol 32: 201-8 (2008)
PM ID: 18097560
20: Zacharoulis S, Ji L, Pollack IF, Duffner P, Geyer R, Grill J, Schild S, Jaing TH, Massimino M, Finlay J, Sposto R
Metastatic ependymoma: a multi-institutional retrospective analysis of prognostic factors.
Pediatr Blood Cancer 50: 231-5 (2008)
PM ID: 17610266
21: Fangusaro J, Finlay J, Sposto R, Ji L, Saly M, Zacharoulis S, Asgharzadeh S, Abromowitch M, Olshefski R, Halpern S, Dubowy R, Comito M, Diez B, Kellie S, Hukin J, Rosenblum M, Dunkel I, Miller DC, Allen J, Gardner S
Intensive chemotherapy followed by consolidative myeloablative chemotherapy with autologous hematopoietic cell rescue (AuHCR) in young children with newly diagnosed supratentorial primitive neuroectodermal tumors (sPNETs): report of the Head Start I and II experience.
Pediatr Blood Cancer 50: 312-8 (2008)
PM ID: 17668858
22: Hao QL, George AA, Zhu JY, Barsky LW, Zielinska E, Wang XD, Price MA, Ge S, Crooks GM
Human intrathymic lineage commitment is marked by differential CD7 expression: identification of CD7- lympho-myeloid thymic progenitors.
Blood 111: 1318-26 (2008)
PM ID: 17959857 PMC2214748
23: Panigrahy A, Nelson MD, Finlay JL, Sposto R, Krieger MD, Gilles FH, Blüml S
Metabolism of diffuse intrinsic brainstem gliomas in children.
Neuro Oncol 10: 32-44 (2008)
PM ID: 18003889 PMC2600836
24: Dowd CL, Sutch BT, Haworth IS, Eritja R, Marquez VE, Yang AS
Incorporation of zebularine from its 2'-deoxyribonucleoside triphosphate derivative and activity as a template-coding nucleobase.
Nucleosides Nucleotides Nucleic Acids 27: 131-45 (2008)
PM ID: 18205068
25: Yue M, Stachowiak JC, Lin HH, Datar R, Cote RJ, Majumdar A
Label-free protein recognition two-dimensional array using nanomechanical sensors.
Nano Lett 8: 520-4 (2008)
PM ID: 18179277
26: Malogolowkin M, Cotton CA, Green DM, Breslow NE, Perlman E, Miser J, Ritchey ML, Thomas PR, Grundy PE, D'Angio GJ, Beckwith JB, Shamberger RC, Haase GM, Donaldson M, Weetman R, Coppes MJ, Shearer P, Coccia P, Kletzel M, Macklis R, Tomlinson G, Huff V, Newbury R, Weeks D, National Wilms Tumor Study Group
Treatment of Wilms tumor relapsing after initial treatment with vincristine, actinomycin D, and doxorubicin. A report from the National Wilms Tumor Study Group.
Pediatr Blood Cancer 50: 236-41 (2008)
PM ID: 17539021
27: Fangusaro JR, Jubran RF, Allen J, Gardner S, Dunkel IJ, Rosenblum M, Atlas MP, Gonzalez-Gomez I, Miller D, Finlay JL
Brainstem primitive neuroectodermal tumors (bstPNET): results of treatment with intensive induction chemotherapy followed by consolidative chemotherapy with autologous hematopoietic cell rescue.
Pediatr Blood Cancer 50: 715-7 (2008)
PM ID: 17009232
28: Rook J, Rosser T, Fangusaro J, Finlay J
Acute transient encephalopathy following paclitaxel treatment in an adolescent with a recurrent suprasellar germinoma.
Pediatr Blood Cancer 50: 699-700 (2008)
PM ID: 16991134
29: Shi SR, Liu C, Pootrakul L, Tang L, Young A, Chen R, Cote RJ, Taylor CR
Evaluation of the value of frozen tissue section used as "gold standard" for immunohistochemistry.
Am J Clin Pathol 129: 358-66 (2008)
PM ID: 18285257
30: Sreekumar PG, Zhou J, Sohn J, Spee C, Ryan SJ, Maurer BJ, Kannan R, Hinton DR
N-(4-hydroxyphenyl) retinamide augments laser-induced choroidal neovascularization in mice.
Invest Ophthalmol Vis Sci 49: 1210-20 (2008)
PM ID: 18326751
31: Dayam R, Al-Mawsawi LQ, Zawahir Z, Witvrouw M, Debyser Z, Neamati N
Quinolone 3-carboxylic acid pharmacophore: design of second generation HIV-1 integrase inhibitors.
J Med Chem 51: 1136-44 (2008)
PM ID: 18281931
32: Gilles FH, Tavaré CJ, Becker LE, Burger PC, Yates AJ, Pollack IF, Finlay JL
Pathologist interobserver variability of histologic features in childhood brain tumors: results from the CCG-945 study.
Pediatr Dev Pathol 11: 108-17 (2008)
PM ID: 17990938
33: Maris JM, Courtright J, Houghton PJ, Morton CL, Gorlick R, Kolb EA, Lock R, Tajbakhsh M, Reynolds CP, Keir ST, Wu J, Smith MA
Initial testing of the VEGFR inhibitor AZD2171 by the pediatric preclinical testing program.
Pediatr Blood Cancer 50: 581-7 (2008)
PM ID: 17457854
34: Abdel-Azim H, Zhu Y, Hollis RP, Wang XD, Ge S, Hao QL, Smbatyan G, Kohn DB, Rosol M, Crooks GM
Expansion of multipotent and lymphoid-committed human progenitors through intracellular dimerization of Mpl.
Blood 111: 4064-74 (2008)
PM ID: 18174381 PMC2288719
35: Rountree CB, Senadheera S, Mato JM, Crooks GM, Lu SC
Expansion of liver cancer stem cells during aging in methionine adenosyltransferase 1A-deficient mice.
Hepatology 47: 1288-97 (2008)
PM ID: 18167064 PMC2408692 NIHMS49822
36: Singh H, Manuri PR, Olivares S, Dara N, Dawson MJ, Huls H, Hackett PB, Kohn DB, Shpall EJ, Champlin RE, Cooper LJ
Redirecting specificity of T-cell populations for CD19 using the Sleeping Beauty system.
Cancer Res 68: 2961-71 (2008)
PM ID: 18413766 PMC2424272 NIHMS52003
37: Houghton PJ, Morton CL, Kolb EA, Gorlick R, Lock R, Carol H, Reynolds CP, Maris JM, Keir ST, Billups CA, Smith MA
Initial testing (stage 1) of the mTOR inhibitor rapamycin by the pediatric preclinical testing program.
Pediatr Blood Cancer 50: 799-805 (2008)
PM ID: 17635004
38: Kang MH, Wan Z, Kang YH, Sposto R, Reynolds CP
Mechanism of synergy of N-(4-hydroxyphenyl)retinamide and ABT-737 in acute lymphoblastic leukemia cell lines: Mcl-1 inactivation.
J Natl Cancer Inst 100: 580-95 (2008)
PM ID: 18398104
39: Kobayashi H, Sugihara K, Uetake H, Higuchi T, Yasuno M, Enomoto M, Kuramochi H, Lenz HJ, Danenberg KD, Danenberg PV
Messenger RNA expression of vascular endothelial growth factor and its receptors in primary colorectal cancer and corresponding liver metastasis.
Ann Surg Oncol 15: 1232-8 (2008)
PM ID: 18239970
40: Al-Mawsawi LQ, Christ F, Dayam R, Debyser Z, Neamati N
Inhibitory profile of a LEDGF/p75 peptide against HIV-1 integrase: insight into integrase-DNA complex formation and catalysis.
FEBS Lett 582: 1425-30 (2008)
PM ID: 18331842
41: Heo K, Kim HJ, Choi SH, Choi J, Kim KJ, Gu J, Lieber MR, Yang AS, An W
FACT-mediated exchange of histone variant H2AX regulated by phosphorylation of H2AX and ADP-ribosylation of Spt16.
Mol Cell 30: 86-97 (2008)
PM ID: 18406329
42: Li K, Xu L, Kulkarni AA, Perkins DI, Haworth IS, Davies DL
Ethanol inhibits functional activity of the human intestinal dipeptide transporter hPepT1 expressed in Xenopus oocytes.
Alcohol Clin Exp Res 32: 777-84 (2008)
PM ID: 18336632
43: Tajbakhsh M, Houghton PJ, Morton CL, Kolb EA, Gorlick R, Maris JM, Keir ST, Wu J, Reynolds CP, Smith MA, Lock RB
Initial testing of cisplatin by the pediatric preclinical testing program.
Pediatr Blood Cancer 50: 992-1000 (2008)
PM ID: 17554786
44: Seymour ZA, Panigrahy A, Finlay JL, Nelson MD, Blüml S
Citrate in pediatric CNS tumors?
AJNR Am J Neuroradiol 29: 1006-11 (2008)
PM ID: 18272551
45: Malogolowkin MH, Katzenstein HM, Krailo M, Chen Z, Quinn JJ, Reynolds M, Ortega JA
Redefining the role of doxorubicin for the treatment of children with hepatoblastoma.
J Clin Oncol 26: 2379-83 (2008)
PM ID: 18467729
46: Brzozowski Z, Slawinski J, Saczewski F, Sanchez TW, Neamati N
Synthesis, anti-HIV-1 integrase, and cytotoxic activities of 4-chloro-N-(4-oxopyrimidin-2-yl)-2-mercaptobenzenesulfonamide derivatives.
Eur J Med Chem 43: 1188-98 (2008)
PM ID: 17949860
47: Dhall G, Grodman H, Ji L, Sands S, Gardner S, Dunkel IJ, McCowage GB, Diez B, Allen JC, Gopalan A, Cornelius AS, Termuhlen A, Abromowitch M, Sposto R, Finlay JL
Outcome of children less than three years old at diagnosis with non-metastatic medulloblastoma treated with chemotherapy on the "Head Start" I and II protocols.
Pediatr Blood Cancer 50: 1169-75 (2008)
PM ID: 18293379
48: Carbonaro DA, Jin X, Cotoi D, Mi T, Yu XJ, Skelton DC, Dorey F, Kellems RE, Blackburn MR, Kohn DB
Neonatal bone marrow transplantation of ADA-deficient SCID mice results in immunologic reconstitution despite low levels of engraftment and an absence of selective donor T lymphoid expansion.
Blood 111: 5745-54 (2008)
PM ID: 18356486 PMC2424166
49: Kolb EA, Gorlick R, Houghton PJ, Morton CL, Lock RB, Tajbakhsh M, Reynolds CP, Maris JM, Keir ST, Billups CA, Smith MA
Initial testing of dasatinib by the pediatric preclinical testing program.
Pediatr Blood Cancer 50: 1198-206 (2008)
PM ID: 17914733
50: Lock R, Carol H, Houghton PJ, Morton CL, Kolb EA, Gorlick R, Reynolds CP, Maris JM, Keir ST, Wu J, Smith MA
Initial testing (stage 1) of the BH3 mimetic ABT-263 by the pediatric preclinical testing program.
Pediatr Blood Cancer 50: 1181-9 (2008)
PM ID: 18085673
51: Kolb EA, Gorlick R, Houghton PJ, Morton CL, Lock R, Carol H, Reynolds CP, Maris JM, Keir ST, Billups CA, Smith MA
Initial testing (stage 1) of a monoclonal antibody (SCH 717454) against the IGF-1 receptor by the pediatric preclinical testing program.
Pediatr Blood Cancer 50: 1190-7 (2008)
PM ID: 18260118
52: Garofalo A, Grande F, Brizzi A, Aiello F, Dayam R, Neamati N
Naphthoxazepine inhibitors of HIV-1 integrase: synthesis and biological evaluation.
ChemMedChem 3: 986-90 (2008)
PM ID: 18383063
53: Chu MW, Siegmund KD, Hao QL, Crooks GM, Tavaré S, Shibata D
Inferring relative numbers of human leucocyte genome replications.
Br J Haematol 141: 862-71 (2008)
PM ID: 18410448
54: Al-Mawsawi LQ, Al-Safi RI, Neamati N
Anti-infectives: clinical progress of HIV-1 integrase inhibitors.
Expert Opin Emerg Drugs 13: 213-25 (2008)
PM ID: 18537517
55: Gundla R, Kazemi R, Sanam R, Muttineni R, Sarma JA, Dayam R, Neamati N
Discovery of novel small-molecule inhibitors of human epidermal growth factor receptor-2: combined ligand and target-based approach.
J Med Chem 51: 3367-77 (2008)
PM ID: 18500794
56: Maris JM, Courtright J, Houghton PJ, Morton CL, Kolb EA, Lock R, Tajbakhsh M, Reynolds CP, Keir ST, Wu J, Smith MA
Initial testing (stage 1) of sunitinib by the pediatric preclinical testing program.
Pediatr Blood Cancer 51: 42-8 (2008)
PM ID: 18293383
57: Smith MA, Morton CL, Phelps DA, Kolb EA, Lock R, Carol H, Reynolds CP, Maris JM, Keir ST, Wu J, Houghton PJ
Stage 1 testing and pharmacodynamic evaluation of the HSP90 inhibitor alvespimycin (17-DMAG, KOS-1022) by the pediatric preclinical testing program.
Pediatr Blood Cancer 51: 34-41 (2008)
PM ID: 18260120
58: Neale G, Su X, Morton CL, Phelps D, Gorlick R, Lock RB, Reynolds CP, Maris JM, Friedman HS, Dome J, Khoury J, Triche TJ, Seeger RC, Gilbertson R, Khan J, Smith MA, Houghton PJ
Molecular characterization of the pediatric preclinical testing panel.
Clin Cancer Res 14: 4572-83 (2008)
PM ID: 18628472
59: Banki F, Yacoub WN, Hagen JA, Mason RJ, Ayazi S, DeMeester SR, Lipham JC, Danenberg K, Danenberg P, DeMeester TR
Plasma DNA is more reliable than carcinoembryonic antigen for diagnosis of recurrent esophageal cancer.
J Am Coll Surg 207: 30-5 (2008)
PM ID: 18589358
60: Hoffmann AC, Mori R, Vallbohmer D, Brabender J, Klein E, Drebber U, Baldus SE, Cooc J, Azuma M, Metzger R, Hoelscher AH, Danenberg KD, Prenzel KL, Danenberg PV
High expression of HIF1a is a predictor of clinical outcome in patients with pancreatic ductal adenocarcinomas and correlated to PDGFA, VEGF, and bFGF.
Neoplasia 10: 674-9 (2008)
PM ID: 18592007 PMC2435004
61: Kahl CA, Cannon PM, Oldenburg J, Tarantal AF, Kohn DB
Tissue-specific restriction of cyclophilin A-independent HIV-1- and SIV-derived lentiviral vectors.
Gene Ther 15: 1079-89 (2008)
PM ID: 18385767
62: Gardner SL, Asgharzadeh S, Green A, Horn B, McCowage G, Finlay J
Intensive induction chemotherapy followed by high dose chemotherapy with autologous hematopoietic progenitor cell rescue in young children newly diagnosed with central nervous system atypical teratoid rhabdoid tumors.
Pediatr Blood Cancer 51: 235-40 (2008)
PM ID: 18381756
63: Byun HM, Choi SH, Laird PW, Trinh BN, Siddiqui MA, Marquez VE, Yang AS
2'-Deoxy-N4-[2-(4-nitrophenyl)ethoxycarbonyl]-5-azacytidine: a novel inhibitor of DNA methyltransferase that requires activation by human carboxylesterase 1.
Cancer Lett 266: 238-48 (2008)
PM ID: 18499340 PMC2528876 NIHMS57985
64: Zeng LF, Zhang HS, Wang YH, Sanchez TW, Zheng YT, Neamati N, Long YQ
Efficient synthesis and utilization of phenyl-substituted heteroaromatic carboxylic acids as aryl diketo acid isosteres in the design of novel HIV-1 integrase inhibitors.
Bioorg Med Chem Lett 18: 4521-4 (2008)
PM ID: 18662877
65: Zeng LF, Jiang XH, Sanchez TW, Zhang HS, Dayam R, Neamati N, Long YQ
Novel dimeric aryldiketo containing inhibitors of HIV-1 integrase: effects of the phenyl substituent and the linker orientation.
Bioorg Med Chem 16: 7777-87 (2008)
PM ID: 18644730
66: Al-Mawsawi LQ, Hombrouck A, Dayam R, Debyser Z, Neamati N
Four-tiered pi interaction at the dimeric interface of HIV-1 integrase critical for DNA integration and viral infectivity.
Virology 377: 355-63 (2008)
PM ID: 18514248
67: Finlay J, da Silva NS, Lavey R, Bouffet E, Kellie SJ, Shaw E, Saran F, Matsutani M
The management of patients with primary central nervous system (CNS) germinoma: current controversies requiring resolution.
Pediatr Blood Cancer 51: 313-6 (2008)
PM ID: 18421722
68: Yoo CB, Chuang JC, Byun HM, Egger G, Yang AS, Dubeau L, Long TI, Laird PW, Marquez VE, Jones PA
Long-term epigenetic therapy with oral zebularine has minimal side effects and prevents intestinal tumors in mice.
Cancer Prev Res (Phila Pa) 1: 233-40 (2008)
PM ID: 19138966
69: Wilson PM, Fazzone W, LaBonte MJ, Deng J, Neamati N, Ladner RD
Novel opportunities for thymidylate metabolism as a therapeutic target.
Mol Cancer Ther 7: 3029-37 (2008)
PM ID: 18790783 PMC2597111 NIHMS68743
70: Wang H, Maurer BJ, Liu YY, Wang E, Allegood JC, Kelly S, Symolon H, Liu Y, Merrill AH, Gouazé-Andersson V, Yu JY, Giuliano AE, Cabot MC
N-(4-Hydroxyphenyl)retinamide increases dihydroceramide and synergizes with dimethylsphingosine to enhance cancer cell killing.
Mol Cancer Ther 7: 2967-76 (2008)
PM ID: 18790777
71: Holschneider DP, Yang J, Sadler TR, Galifianakis NB, Bozorgzadeh MH, Bading JR, Conti PS, Maarek JM
Changes in regional brain perfusion during functional brain activation: comparison of [(64)Cu]-PTSM with [(14)C]-Iodoantipyrine.
Brain Res 1234: 32-43 (2008)
PM ID: 18687316 PMC2578839 NIHMS73066
72: Ramkumar K, Tambov KV, Gundla R, Manaev AV, Manaev AV, Yarovenko V, Traven VF, Neamati N
Discovery of 3-acetyl-4-hydroxy-2-pyranone derivatives and their difluoridoborate complexes as a novel class of HIV-1 integrase inhibitors.
Bioorg Med Chem 16: 8988-98 (2008)
PM ID: 18805696
73: Mori R, Wang Q, Danenberg KD, Pinski JK, Danenberg PV
Both beta-actin and GAPDH are useful reference genes for normalization of quantitative RT-PCR in human FFPE tissue samples of prostate cancer.
Prostate 68: 1555-60 (2008)
PM ID: 18651557
74: Abromowitch M, Sposto R, Perkins S, Zwick D, Siegel S, Finlay J, Cairo MS, Children's Oncology Group
Shortened intensified multi-agent chemotherapy and non-cross resistant maintenance therapy for advanced lymphoblastic lymphoma in children and adolescents: report from the Children's Oncology Group.
Br J Haematol 143: 261-7 (2008)
PM ID: 18759768
75: Hoffmann AC, Mori R, Vallbohmer D, Brabender J, Drebber U, Baldus SE, Klein E, Azuma M, Metzger R, Hoffmann C, Hoelscher AH, Danenberg KD, Prenzel KL, Danenberg PV
High expression of heparanase is significantly associated with dedifferentiation and lymph node metastasis in patients with pancreatic ductal adenocarcinomas and correlated to PDGFA and via HIF1a to HB-EGF and bFGF.
J Gastrointest Surg 12: 1674-81; discussion 1681-2 (2008)
PM ID: 18704599
76: Somlo G, Chu P, Frankel P, Ye W, Groshen S, Doroshow JH, Danenberg K, Danenberg P
Molecular profiling including epidermal growth factor receptor and p21 expression in high-risk breast cancer patients as indicators of outcome.
Ann Oncol 19: 1853-9 (2008)
PM ID: 18641005 PMC2733077
77: Deng J, Taheri L, Grande F, Aiello F, Garofalo A, Neamati N
Discovery of novel anticancer compounds based on a quinoxalinehydrazine pharmacophore.
ChemMedChem 3: 1677-86 (2008)
PM ID: 18985651
78: Bacchi A, Biemmi M, Carcelli M, Carta F, Compari C, Fisicaro E, Rogolino D, Sechi M, Sippel M, Sotriffer CA, Sanchez TW, Neamati N
From ligand to complexes. Part 2. Remarks on human immunodeficiency virus type 1 integrase inhibition by beta-diketo acid metal complexes.
J Med Chem 51: 7253-64 (2008)
PM ID: 18983138
79: Kuramochi H, Hayashi K, Uchida K, Nakajima G, Hatori T, Danenberg KD, Danenberg PV, Yamamoto M
High intratumoral dihydropyrimidine dehydrogenase mRNA levels in pancreatic cancer associated with a high rate of response to S-1.
Cancer Chemother Pharmacol 63: 85-9 (2008)
PM ID: 18309485
80: Fukui Y, Oka T, Nagayama S, Danenberg PV, Danenberg KD, Fukushima M
Thymidylate synthase, dihydropyrimidine dehydrogenase, orotate phosphoribosyltransferase mRNA and protein expression levels in solid tumors in large scale population analysis.
Int J Mol Med 22: 709-16 (2008)
PM ID: 19020767
81: Kobayashi H, Sugihara K, Uetake H, Higuchi T, Yasuno M, Enomoto M, Iida S, Azuma M, Mori R, Omori A, Lenz HJ, Danenberg KD, Danenberg PV
Messenger RNA expression of TS and ERCC1 in colorectal cancer and matched liver metastasis.
Int J Oncol 33: 1257-62 (2008)
PM ID: 19020759
82: Finlay JL, Dhall G, Boyett JM, Dunkel IJ, Gardner SL, Goldman S, Yates AJ, Rosenblum MK, Stanley P, Zimmerman RA, Wallace D, Pollack IF, Packer RJ, Children's Cancer Group
Myeloablative chemotherapy with autologous bone marrow rescue in children and adolescents with recurrent malignant astrocytoma: outcome compared with conventional chemotherapy: a report from the Children's Oncology Group.
Pediatr Blood Cancer 51: 806-11 (2008)
PM ID: 18802947
83: Kim A, Ji L, Balmaceda C, Diez B, Kellie SJ, Dunkel IJ, Gardner SL, Sposto R, Finlay JL
The prognostic value of tumor markers in newly diagnosed patients with primary central nervous system germ cell tumors.
Pediatr Blood Cancer 51: 768-73 (2008)
PM ID: 18802946
84: Jao CC, Hegde BG, Chen J, Haworth IS, Langen R
Structure of membrane-bound alpha-synuclein from site-directed spin labeling and computational refinement.
Proc Natl Acad Sci U S A 105: 19666-71 (2008)
PM ID: 19066219 PMC2605001
85: Weber JS, O'Day S, Urba W, Powderly J, Nichol G, Yellin M, Snively J, Hersh E
Phase I/II study of ipilimumab for patients with metastatic melanoma.
J Clin Oncol 26: 5950-6 (2008)
PM ID: 19018089
86: Fangusaro JR, Finlay JL
Radiation therapy approaches do not currently improve overall survival in young children with sPNET as compared to the Head Start I and II experience.
Pediatr Blood Cancer 51: 149-150 (2008)
PM ID: 18260116
87: Mitra AP, Cote RJ
Molecular pathogenesis and diagnostics of bladder cancer.
Annu Rev Pathol 4: 251-85 (2009)
PM ID: 18840072
88: Serrao E, Odde S, Ramkumar K, Neamati N
Raltegravir, elvitegravir, and metoogravir: the birth of "me-too" HIV-1 integrase inhibitors.
Retrovirology 6: 25 (2009)
PM ID: 19265512 PMC2660292
89: Kuramochi H, Uchida K, Peters JH, Shimizu D, Vallbohmer D, Schneider S, Danenberg KD, Danenberg PV
Loss of heterozygosity at thymidylate synthase locus in Barrett's metaplasia, dysplasia, and carcinoma sequences.
BMC Cancer 9: 157 (2009)
PM ID: 19460136 PMC2694818
90: Grimminger PP, Stöhlmacher J, Vallböhmer D, Schneider PM, Hölscher AH, Metzger R, Danenberg PV, Brabender J
Prognostic Significance and Clinicopathological Associations of COX-2 SNP in Patients with Nonsmall Cell Lung Cancer.
J Oncol 2009: 139590 (2009)
PM ID: 20016751 PMC2793422
91: Brzozowski Z, Saczewski F, Slawinski J, Sanchez TW, Neamati N
Synthesis and anti-HIV-1 integrase activities of 3-aroyl-2,3-dihydro-1,1-dioxo-1,4,2-benzodithiazines.
Eur J Med Chem 44: 190-6 (2009)
PM ID: 18394758
92: Mori R, Xiong S, Wang Q, Tarabolous C, Shimada H, Panteris E, Danenberg KD, Danenberg PV, Pinski JK
Gene profiling and pathway analysis of neuroendocrine transdifferentiated prostate cancer cells.
Prostate 69: 12-23 (2009)
PM ID: 18814146
93: Sherman CB, Ali-Nazir A, Gonzales-Gomez I, Finlay JL, Dhall G
Primary mixed glioneuronal tumor of the central nervous system in a patient with noonan syndrome: a case report and review of the literature.
J Pediatr Hematol Oncol 31: 61-4 (2009)
PM ID: 19125092
94: Javahery RJ, Davidson L, Fangusaro J, Finlay JL, Gonzalez-Gomez I, McComb JG
Aggressive variant of a papillary glioneuronal tumor. Report of 2 cases.
J Neurosurg Pediatr 3: 46-52 (2009)
PM ID: 19119904
95: Park JR, Villablanca JG, London WB, Gerbing RB, Haas-Kogan D, Adkins ES, Attiyeh EF, Maris JM, Seeger RC, Reynolds CP, Matthay KK, Children's Oncology Group
Outcome of high-risk stage 3 neuroblastoma with myeloablative therapy and 13-cis-retinoic acid: a report from the Children's Oncology Group.
Pediatr Blood Cancer 52: 44-50 (2009)
PM ID: 18937318 PMC2731719 NIHMS123682
96: Zawahir Z, Dayam R, Deng J, Pereira C, Neamati N
Pharmacophore guided discovery of small-molecule human apurinic/apyrimidinic endonuclease 1 inhibitors.
J Med Chem 52: 20-32 (2009)
PM ID: 19072053
97: Cheung E, Pinski J, Dorff T, Groshen S, Quinn DI, Reynolds CP, Maurer BJ, Lara PN, Tsao-Wei DD, Twardowski P, Chatta G, McNamara M, Gandara DR
Oral fenretinide in biochemically recurrent prostate cancer: a California cancer consortium phase II trial.
Clin Genitourin Cancer 7: 43-50 (2009)
PM ID: 19213668
98: Ohta S, Uemura H, Matsui Y, Ishiguro H, Fujinami K, Kondo K, Miyamoto H, Yazawa T, Danenberg K, Danenberg PV, Tohnai I, Kubota Y
Alterations of p16 and p14ARF genes and their 9p21 locus in oral squamous cell carcinoma.
Oral Surg Oral Med Oral Pathol Oral Radiol Endod 107: 81-91 (2009)
PM ID: 19101490
99: Youssef RF, Mitra AP, Bartsch G, Jones PA, Skinner DG, Cote RJ
Molecular targets and targeted therapies in bladder cancer management.
World J Urol 27: 9-20 (2009)
PM ID: 19039591
100: Kang MH, Reynolds CP
Bcl-2 inhibitors: targeting mitochondrial apoptotic pathways in cancer therapy.
Clin Cancer Res 15: 1126-32 (2009)
PM ID: 19228717
101: Tsai AG, Engelhart AE, Hatmal MM, Houston SI, Hud NV, Haworth IS, Lieber MR
Conformational variants of duplex DNA correlated with cytosine-rich chromosomal fragile sites.
J Biol Chem 284: 7157-64 (2009)
PM ID: 19106104 PMC2652318 [Available on 03/13/10]
102: Matthay KK, Reynolds CP, Seeger RC, Shimada H, Adkins ES, Haas-Kogan D, Gerbing RB, London WB, Villablanca JG
Long-term results for children with high-risk neuroblastoma treated on a randomized trial of myeloablative therapy followed by 13-cis-retinoic acid: a children's oncology group study.
J Clin Oncol 27: 1007-13 (2009)
PM ID: 19171716 PMC2738615 [Available on 03/01/10]
103: Cao X, Plasencia C, Kanzaki A, Yang A, Burke TR, Neamati N
Elucidation of the molecular mechanisms of a salicylhydrazide class of compounds by proteomic analysis.
Curr Cancer Drug Targets 9: 189-201 (2009)
PM ID: 19275759
104: Plasencia C, Grande F, Oshima T, Cao X, Yamada R, Sanchez T, Aiello F, Garofalo A, Neamati N
Discovery of a novel quinoxalinhydrazide with a broad-spectrum anticancer activity.
Cancer Biol Ther 8: 458-65 (2009)
PM ID: 19221468
105: Sechi M, Carta F, Sannia L, Dallocchio R, Dessì A, Al-Safi RI, Neamati N
Design, synthesis, molecular modeling, and anti-HIV-1 integrase activity of a series of photoactivatable diketo acid-containing inhibitors as affinity probes.
Antiviral Res 81: 267-76 (2009)
PM ID: 19135482
106: Lowe EJ, Sposto R, Perkins SL, Gross TG, Finlay J, Zwick D, Abromowitch M, Children's Cancer Group Study 5941
Intensive chemotherapy for systemic anaplastic large cell lymphoma in children and adolescents: final results of Children's Cancer Group Study 5941.
Pediatr Blood Cancer 52: 335-9 (2009)
PM ID: 18985718 PMC2769495 [Available on 03/01/10] NIHMS123401 [Available on 03/01/10]
107: Wagner LM, Villablanca JG, Stewart CF, Crews KR, Groshen S, Reynolds CP, Park JR, Maris JM, Hawkins RA, Daldrup-Link HE, Jackson HA, Matthay KK
Phase I trial of oral irinotecan and temozolomide for children with relapsed high-risk neuroblastoma: a new approach to neuroblastoma therapy consortium study.
J Clin Oncol 27: 1290-6 (2009)
PM ID: 19171709 PMC2667827 [Available on 03/10/10]
108: Balic M, Pichler M, Strutz J, Heitzer E, Ausch C, Samonigg H, Cote RJ, Dandachi N
High quality assessment of DNA methylation in archival tissues from colorectal cancer patients using quantitative high-resolution melting analysis.
J Mol Diagn 11: 102-8 (2009)
PM ID: 19179456 PMC2665859 [Available on 03/01/10]
109: Sechi M, Rizzi G, Bacchi A, Carcelli M, Rogolino D, Pala N, Sanchez TW, Taheri L, Dayam R, Neamati N
Design and synthesis of novel dihydroquinoline-3-carboxylic acids as HIV-1 integrase inhibitors.
Bioorg Med Chem 17: 2925-35 (2009)
PM ID: 19026554
110: Aparicio A, North B, Barske L, Wang X, Bollati V, Weisenberger D, Yoo C, Tannir N, Horne E, Groshen S, Jones P, Yang A, Issa JP
LINE-1 methylation in plasma DNA as a biomarker of activity of DNA methylation inhibitors in patients with solid tumors.
Epigenetics 4: 176-84 (2009)
PM ID: 19421002
111: Martinez-Balibrea E, Plasencia C, Ginés A, Martinez-Cardús A, Musulén E, Aguilera R, Manzano JL, Neamati N, Abad A
A proteomic approach links decreased pyruvate kinase M2 expression to oxaliplatin resistance in patients with colorectal cancer and in human cell lines.
Mol Cancer Ther 8: 771-8 (2009)
PM ID: 19372549
112: Li HY, Wang CY, Sanchez TW, Tan Y, Jiang C, Neamati N, Zhao G
Amide-containing diketoacids as HIV-1 integrase inhibitors: synthesis, structure-activity relationship analysis, and biological activity.
Bioorg Med Chem 17: 2913-9 (2009)
PM ID: 19269185
113: Kobayashi H, Sugihara K, Uetake H, Higuchi T, Yasuno M, Enomoto M, Iida S, Lenz HJ, Danenberg KD, Danenberg PV
Messenger RNA expression of COX-2 and angiogenic factors in primary colorectal cancer and corresponding liver metastasis.
Int J Oncol 34: 1147-53 (2009)
PM ID: 19287974
114: Grande F, Yamada R, Cao X, Aiello F, Garofalo A, Neamati N
Synthesis and biological evaluation of novel hydrazide based cytotoxic agents.
Expert Opin Investig Drugs 18: 555-68 (2009)
PM ID: 19388873
115: Volchenboum SL, Li C, Li S, Attiyeh EF, Reynolds CP, Maris JM, Look AT, George RE
Comparison of primary neuroblastoma tumors and derivative early-passage cell lines using genome-wide single nucleotide polymorphism array analysis.
Cancer Res 69: 4143-9 (2009)
PM ID: 19435921 PMC2739280 [Available on 05/15/10] NIHMS119938 [Available on 05/15/10]
116: Oh DS, DeMeester SR, Dunst CM, Mori R, Lehman BJ, Kuramochi H, Danenberg K, Danenberg P, Hagen JA, Chandrasoma PT, DeMeester TR
Validation of a rodent model of Barrett's esophagus using quantitative gene expression profiling.
Surg Endosc 23: 1346-52 (2009)
PM ID: 18813976
117: Oshima T, Cao X, Grande F, Yamada R, Garofalo A, Louie S, Neamati N
Combination effects of SC144 and cytotoxic anticancer agents.
Anticancer Drugs 20: 312-20 (2009)
PM ID: 19322070
118: Martinez-Balibrea E, Martínez-Cardús A, Musulén E, Ginés A, Manzano JL, Aranda E, Plasencia C, Neamati N, Abad A
Increased levels of copper efflux transporter ATP7B are associated with poor outcome in colorectal cancer patients receiving oxaliplatin-based chemotherapy.
Int J Cancer 124: 2905-10 (2009)
PM ID: 19296535
119: Rosol M, Harutyunyan I, Xu J, Melendez E, Smbatyan G, Finlay JL, Krieger MD, Gonzalez-Gomez I, Reynolds CP, Nelson MD, Erdreich-Epstein A, Blüml S
Metabolism of orthotopic mouse brain tumor models.
Mol Imaging 8: 199-208 (2009)
PM ID: 19728974
120: Butturini AM, Jacob M, Aguajo J, Vander-Walde NA, Villablanca J, Jubran R, Erdreich-Epstein A, Marachelian A, Dhall G, Finlay JL
High-dose chemotherapy and autologous hematopoietic progenitor cell rescue in children with recurrent medulloblastoma and supratentorial primitive neuroectodermal tumors: the impact of prior radiotherapy on outcome.
Cancer 115: 2956-63 (2009)
PM ID: 19402050
121: Shariat SF, Bolenz C, Karakiewicz PI, Fradet Y, Ashfaq R, Bastian PJ, Nielsen ME, Capitanio U, Jeldres C, Rigaud J, Müller SC, Lerner SP, Montorsi F, Sagalowsky AI, Cote RJ, Lotan Y
p53 expression in patients with advanced urothelial cancer of the urinary bladder.
BJU Int : (2009)
PM ID: 19659466
122: Wang DS, Dake MD, Park JM, Kuo MD
Molecular imaging: a primer for interventionalists and imagers.
J Vasc Interv Radiol 20: S505-22 (2009)
PM ID: 19560036
123: Choi SH, Worswick SD, Byun HM, Shear T, Soussa JC, Wolff EM, Douer D, Garcia-Manero G, Liang G, Yang AS
Changes in DNA methylation of tandem DNA repeats are different from interspersed repeats in cancer.
Int J Cancer 125: 723-9 (2009)
PM ID: 19437537
124: Mitra AP, Pagliarulo V, Yang D, Waldman FM, Datar RH, Skinner DG, Groshen S, Cote RJ
Generation of a concise gene panel for outcome prediction in urinary bladder cancer.
J Clin Oncol 27: 3929-37 (2009)
PM ID: 19620494
125: Wang P, Liu CW, Sanches T, Zhong Y, Liu BY, Xiong J, Neamati N, Zhao G
Design and synthesis of novel nitrogen-containing polyhydroxylated aromatics as HIV-1 integrase inhibitors from caffeic acid phenethyl ester.
Bioorg Med Chem Lett 19: 4574-8 (2009)
PM ID: 19625188
126: Hoffman AC, Danenberg KD, Taubert H, Danenberg PV, Wuerl P
A three-gene signature for outcome in soft tissue sarcoma.
Clin Cancer Res 15: 5191-8 (2009)
PM ID: 19671876
127: Sutch BT, Chambers EJ, Bayramyan MZ, Gallaher TK, Haworth IS
Similarity of protein-RNA interfaces based on motif analysis.
J Chem Inf Model 49: 2139-46 (2009)
PM ID: 19731952
128: Birkhahn M, Mitra AP, Williams AJ, Lam GN, Ye W, Datar RH, Balic M, Groshen S, Steven KE, Cote RJ
Predicting Recurrence and Progression of Noninvasive Papillary Bladder Cancer at Initial Presentation Based on Quantitative Gene Expression Profiles.
Eur Urol : (2009)
PM ID: 19762144
129: Keshelava N, Houghton PJ, Morton CL, Lock RB, Carol H, Keir ST, Maris JM, Reynolds CP, Gorlick R, Kolb EA, Wu J, Smith MA
Initial testing (stage 1) of vorinostat (SAHA) by the pediatric preclinical testing program.
Pediatr Blood Cancer 53: 505-8 (2009)
PM ID: 19418547 PMC2752378 [Available on 09/01/10] NIHMS123105 [Available on 09/01/10]
130: Morton CL, Houghton PJ, Gorlick R, Kolb EA, Lock R, Carol H, Keir ST, Reynolds CP, Kang MH, Maris JM, Billups C, Smith MA
Initial testing of aplidin by the pediatric pre-clinical testing program.
Pediatr Blood Cancer 53: 509-12 (2009)
PM ID: 19418543 PMC2777698 NIHMS123399
131: Shariat SF, Lotan Y, Karakiewicz PI, Ashfaq R, Isbarn H, Fradet Y, Bastian PJ, Nielsen ME, Capitanio U, Jeldres C, Montorsi F, Müller SC, Karam JA, Heukamp LC, Netto G, Lerner SP, Sagalowsky AI, Cote RJ
p53 predictive value for pT1-2 N0 disease at radical cystectomy.
J Urol 182: 907-13 (2009)
PM ID: 19616250
132: Xu L, Haworth IS, Kulkarni AA, Bolger MB, Davies DL
Mutagenesis and cysteine scanning of transmembrane domain 10 of the human dipeptide transporter.
Pharm Res 26: 2358-66 (2009)
PM ID: 19685173
133: Gorlick R, Kolb EA, Houghton PJ, Morton CL, Phelps D, Schaiquevich P, Stewart C, Keir ST, Lock R, Carol H, Reynolds CP, Maris JM, Wu J, Smith MA
Initial testing (stage 1) of lapatinib by the pediatric preclinical testing program.
Pediatr Blood Cancer 53: 594-8 (2009)
PM ID: 19554571 PMC2731000 NIHMS123092
134: Pathania D, Millard M, Neamati N
Opportunities in discovery and delivery of anticancer drugs targeting mitochondria and cancer cell metabolism.
Adv Drug Deliv Rev 61: 1250-75 (2009)
PM ID: 19716393
135: Katzenstein HM, Chang KW, Krailo M, Chen Z, Finegold MJ, Rowland J, Reynolds M, Pappo A, London WB, Malogolowkin M, Children's Oncology Group
Amifostine does not prevent platinum-induced hearing loss associated with the treatment of children with hepatoblastoma: a report of the Intergroup Hepatoblastoma Study P9645 as a part of the Children's Oncology Group.
Cancer 115: 5828-35 (2009)
PM ID: 19813275
136: Byun HM, Siegmund KD, Pan F, Weisenberger DJ, Kanel G, Laird PW, Yang AS
Epigenetic profiling of somatic tissues from human autopsy specimens identifies tissue- and individual-specific DNA methylation patterns.
Hum Mol Genet 18: 4808-17 (2009)
PM ID: 19776032
137: Sumiyoshi T, Holt NG, Hollis RP, Ge S, Cannon PM, Crooks GM, Kohn DB
Stable transgene expression in primitive human CD34+ hematopoietic stem/progenitor cells, using the Sleeping Beauty transposon system.
Hum Gene Ther 20: 1607-26 (2009)
PM ID: 19689196
138: Chen TT, Rakheja D, Hung JY, Hornsby PJ, Tabaczewski P, Malogolowkin M, Feusner J, Miskevich F, Schultz R, Tomlinson GE
Establishment and characterization of a cancer cell line derived from an aggressive childhood liver tumor.
Pediatr Blood Cancer 53: 1040-7 (2009)
PM ID: 19637320
139: Meyers RL, Rowland JR, Krailo M, Chen Z, Katzenstein HM, Malogolowkin MH
Predictive power of pretreatment prognostic factors in children with hepatoblastoma: a report from the Children's Oncology Group.
Pediatr Blood Cancer 53: 1016-22 (2009)
PM ID: 19588519
140: Carol H, Lock R, Houghton PJ, Morton CL, Kolb EA, Gorlick R, Reynolds CP, Maris JM, Keir ST, Billups CA, Smith MA
Initial testing (stage 1) of the kinesin spindle protein inhibitor ispinesib by the pediatric preclinical testing program.
Pediatr Blood Cancer 53: 1255-63 (2009)
PM ID: 19554570 PMC2763980 NIHMS123095
141: O'Day SJ, Atkins MB, Boasberg P, Wang HJ, Thompson JA, Anderson CM, Gonzalez R, Lutzky J, Amatruda T, Hersh EM, Weber JS
Phase II multicenter trial of maintenance biotherapy after induction concurrent Biochemotherapy for patients with metastatic melanoma.
J Clin Oncol 27: 6207-12 (2009)
PM ID: 19917850
142: Spreafico F, Pritchard Jones K, Malogolowkin MH, Bergeron C, Hale J, de Kraker J, Dallorso S, Acha T, de Camargo B, Dome JS, Graf N
Treatment of relapsed Wilms tumors: lessons learned.
Expert Rev Anticancer Ther 9: 1807-15 (2009)
PM ID: 19954292
143: Ramajayam R, Mahera NB, Neamati N, Yadav MR, Giridhar R
Synthesis and anti-HIV-1 integrase activity of cyano pyrimidinones.
Arch Pharm (Weinheim) 342: 710-5 (2009)
PM ID: 19899101
144: Millard M, Pathania D, Shabaik Y, Taheri L, Deng J, Neamati N
Preclinical evaluation of novel triphenylphosphonium salts with broad-spectrum activity.
PLoS One 5: (2010)
PM ID: 20957228 PMC2949386
145: Kapranov P, St Laurent G, Raz T, Ozsolak F, Reynolds CP, Sorensen PH, Reaman G, Milos P, Arceci RJ, Thompson JF, Triche TJ
The majority of total nuclear-encoded non-ribosomal RNA in a human cell is 'dark matter' un-annotated RNA.
BMC Biol 8: 149 (2010)
PM ID: 21176148 PMC3022773
146: Smith MA, Morton CL, Kolb EA, Gorlick R, Keir ST, Carol H, Lock R, Kang MH, Reynolds CP, Maris JM, Watkins AE, Houghton PJ
Initial testing (stage 1) of mapatumumab (HGS-ETR1) by the pediatric preclinical testing program.
Pediatr Blood Cancer 54: 307-10 (2010)
PM ID: 19856388 PMC2794954 NIHMS123744
147: Yamada R, Kostova MB, Anchoori RK, Xu S, Neamati N, Khan SR
Biological evaluation of paclitaxel-peptide conjugates as a model for MMP2-targeted drug delivery.
Cancer Biol Ther 9: 192-203 (2010)
PM ID: 20023432
148: Sanam R, Tajne S, Gundla R, Vadivelan S, Machiraju PK, Dayam R, Narasu L, Jagarlapudi S, Neamati N
Combined pharmacophore and structure-guided studies to identify diverse HSP90 inhibitors.
J Mol Graph Model 28: 472-7 (2010)
PM ID: 20005756
149: Dunkel IJ, Jubran RF, Gururangan S, Chantada GL, Finlay JL, Goldman S, Khakoo Y, O'Brien JM, Orjuela M, Rodriguez-Galindo C, Souweidane MM, Abramson DH
Trilateral retinoblastoma: potentially curable with intensive chemotherapy.
Pediatr Blood Cancer 54: 384-7 (2010)
PM ID: 19908299
150: Dunkel IJ, Gardner SL, Garvin JH, Goldman S, Shi W, Finlay JL
High-dose carboplatin, thiotepa, and etoposide with autologous stem cell rescue for patients with previously irradiated recurrent medulloblastoma.
Neuro Oncol 12: 297-303 (2010)
PM ID: 20167818 PMC2940591
151: Serowka K, Chiu Y, Gonzalez I, Gilles F, McComb G, Krieger M, Dhall G, Britt B, Ji L, Sposto R, Finlay JL
Central nervous system (CNS) tumors in the first six months of life: the Children's Hospital Los Angeles experience, 1979-2005.
Pediatr Hematol Oncol 27: 90-102 (2010)
PM ID: 20201690
152: da Silva NS, Cappellano AM, Diez B, Cavalheiro S, Gardner S, Wisoff J, Kellie S, Parker R, Garvin J, Finlay J
Primary chemotherapy for intracranial germ cell tumors: results of the third international CNS germ cell tumor study.
Pediatr Blood Cancer 54: 377-83 (2010)
PM ID: 20063410
153: Sands SA, Oberg JA, Gardner SL, Whiteley JA, Glade-Bender JL, Finlay JL
Neuropsychological functioning of children treated with intensive chemotherapy followed by myeloablative consolidation chemotherapy and autologous hematopoietic cell rescue for newly diagnosed CNS tumors: an analysis of the Head Start II survivors.
Pediatr Blood Cancer 54: 429-36 (2010)
PM ID: 20052775
154: Shamberger RC, Anderson JR, Breslow NE, Perlman EJ, Beckwith JB, Ritchey ML, Haase GM, Donaldson M, Grundy PE, Weetman R, Coppes MJ, Malogolowkin M, Shearer PD, Kletzel M, Thomas PR, Macklis R, Huff V, Weeks DA, Green DM
Long-term outcomes for infants with very low risk Wilms tumor treated with surgery alone in National Wilms Tumor Study-5.
Ann Surg 251: 555-8 (2010)
PM ID: 20142733 PMC2836016 NIHMS169913
155: Grimminger PP, Schneider PM, Metzger R, Vallböhmer D, Danenberg KD, Danenberg PV, Hölscher AH, Brabender J
Ornithine decarboxylase mRNA expression in curatively resected non-small-cell lung cancer.
Clin Lung Cancer 11: 114-9 (2010)
PM ID: 20199977
156: Kuramochi H, Hayashi K, Nakajima G, Kamikozuru H, Yamamoto M, Danenberg KD, Danenberg PV
Epidermal growth factor receptor (EGFR) mRNA levels and protein expression levels in primary colorectal cancer and corresponding liver metastases.
Cancer Chemother Pharmacol 65: 825-31 (2010)
PM ID: 19701635
157: Wolff EM, Byun HM, Han HF, Sharma S, Nichols PW, Siegmund KD, Yang AS, Jones PA, Liang G
Hypomethylation of a LINE-1 promoter activates an alternate transcript of the MET oncogene in bladders with cancer.
PLoS Genet 6: e1000917 (2010)
PM ID: 20421991 PMC2858672
158: Si SJ, Khatua S, Dhall G, Nelson MD, Gonzalez-Gomez I, Finlay JL
Regression of primary central nervous system germinoma after dexamethasone administration: a case report.
Pediatr Hematol Oncol 27: 237-43 (2010)
PM ID: 20367268
159: Tabori U, Shlien A, Baskin B, Levitt S, Ray P, Alon N, Hawkins C, Bouffet E, Pienkowska M, Lafay-Cousin L, Gozali A, Zhukova N, Shane L, Gonzalez I, Finlay J, Malkin D
TP53 alterations determine clinical subgroups and survival of patients with choroid plexus tumors.
J Clin Oncol 28: 1995-2001 (2010)
PM ID: 20308654
160: Finlay JL, Massimino M
A consensus and state-of-the-art workshop: marrow ablative chemotherapy with hematopoietic cell rescue for malignant brain tumors of childhood and adolescence.
Pediatr Blood Cancer 54: 634 (2010)
PM ID: 20146221
161: Massimino M, Cohen KJ, Finlay JL
Is there a role for myeloablative chemotherapy with autologous hematopoietic cell rescue in the management of childhood high-grade astrocytomas?
Pediatr Blood Cancer 54: 641-3 (2010)
PM ID: 20146219
162: Rutkowski S, Cohen B, Finlay J, Luksch R, Ridola V, Valteau-Couanet D, Hara J, Garre ML, Grill J
Medulloblastoma in young children.
Pediatr Blood Cancer 54: 635-7 (2010)
PM ID: 20146217
163: Les AS, Shadden SC, Figueroa CA, Park JM, Tedesco MM, Herfkens RJ, Dalman RL, Taylor CA
Quantification of hemodynamics in abdominal aortic aneurysms during rest and exercise using magnetic resonance imaging and computational fluid dynamics.
Ann Biomed Eng 38: 1288-313 (2010)
PM ID: 20143263
164: Romero RM, Eriksen SP, Haworth IS
Quantitative assessment of assisted problem-based learning in a pharmaceutics course.
Am J Pharm Educ 74: 66 (2010)
PM ID: 20585427 PMC2879117
165: Kang HG, Jenabi JM, Liu XF, Reynolds CP, Triche TJ, Sorensen PH
Inhibition of the insulin-like growth factor I receptor by epigallocatechin gallate blocks proliferation and induces the death of Ewing tumor cells.
Mol Cancer Ther 9: 1396-407 (2010)
PM ID: 20423994
166: Cheng Z, De Jesus OP, Kramer DJ, De A, Webster JM, Gheysens O, Levi J, Namavari M, Wang S, Park JM, Zhang R, Liu H, Lee B, Syud FA, Gambhir SS
64Cu-labeled affibody molecules for imaging of HER2 expressing tumors.
Mol Imaging Biol 12: 316-24 (2010)
PM ID: 19779897
167: Jao CC, Hegde BG, Gallop JL, Hegde PB, McMahon HT, Haworth IS, Langen R
Roles of amphipathic helices and the bin/amphiphysin/rvs (BAR) domain of endophilin in membrane curvature generation.
J Biol Chem 285: 20164-70 (2010)
PM ID: 20418375 PMC2888429
168: Horton TM, Sposto R, Brown P, Reynolds CP, Hunger SP, Winick NJ, Raetz EA, Carroll WL, Arceci RJ, Borowitz MJ, Gaynon PS, Gore L, Jeha S, Maurer BJ, Siegel SE, Biondi A, Kearns PR, Narendran A, Silverman LB, Smith MA, Zwaan CM, Whitlock JA, ALLNA 2008 Conference
Toxicity assessment of molecularly targeted drugs incorporated into multiagent chemotherapy regimens for pediatric acute lymphocytic leukemia (ALL): review from an international consensus conference.
Pediatr Blood Cancer 54: 872-8 (2010)
PM ID: 20127846 PMC2857540 NIHMS163748
169: Khatua S, Dhall G, O'Neil S, Jubran R, Villablanca JG, Marachelian A, Nastia A, Lavey R, Olch AJ, Gonzalez I, Gilles F, Nelson M, Panigrahy A, McComb G, Krieger M, Fan J, Sposto R, Finlay JL
Treatment of primary CNS germinomatous germ cell tumors with chemotherapy prior to reduced dose whole ventricular and local boost irradiation.
Pediatr Blood Cancer 55: 42-6 (2010)
PM ID: 20222020
170: Moreno L, Pollack IF, Duffner PK, Geyer JR, Grill J, Massimino M, Finlay JL, Zacharoulis S
Utility of cerebrospinal fluid cytology in newly diagnosed childhood ependymoma.
J Pediatr Hematol Oncol 32: 515-8 (2010)
PM ID: 20463607
171: Holt N, Wang J, Kim K, Friedman G, Wang X, Taupin V, Crooks GM, Kohn DB, Gregory PD, Holmes MC, Cannon PM
Human hematopoietic stem/progenitor cells modified by zinc-finger nucleases targeted to CCR5 control HIV-1 in vivo.
Nat Biotechnol 28: 839-47 (2010)
PM ID: 20601939 PMC3080757 NIHMS216984
172: Souweidane MM, Krieger MD, Weiner HL, Finlay JL
Surgical management of primary central nervous system germ cell tumors: proceedings from the Second International Symposium on Central Nervous System Germ Cell Tumors.
J Neurosurg Pediatr 6: 125-30 (2010)
PM ID: 20672932
173: Hoffmann AC, Wild P, Leicht C, Bertz S, Danenberg KD, Danenberg PV, Stöhr R, Stöckle M, Lehmann J, Schuler M, Hartmann A
MDR1 and ERCC1 expression predict outcome of patients with locally advanced bladder cancer receiving adjuvant chemotherapy.
Neoplasia 12: 628-36 (2010)
PM ID: 20689757 PMC2915407
174: Yu AL, Gilman AL, Ozkaynak MF, London WB, Kreissman SG, Chen HX, Smith M, Anderson B, Villablanca JG, Matthay KK, Shimada H, Grupp SA, Seeger R, Reynolds CP, Buxton A, Reisfeld RA, Gillies SD, Cohn SL, Maris JM, Sondel PM, Children's Oncology Group
Anti-GD2 antibody with GM-CSF, interleukin-2, and isotretinoin for neuroblastoma.
N Engl J Med 363: 1324-34 (2010)
PM ID: 20879881 PMC3086629 NIHMS245842
175: Baker DL, Schmidt ML, Cohn SL, Maris JM, London WB, Buxton A, Stram D, Castleberry RP, Shimada H, Sandler A, Shamberger RC, Look AT, Reynolds CP, Seeger RC, Matthay KK, Children’s Oncology Group
Outcome after reduced chemotherapy for intermediate-risk neuroblastoma.
N Engl J Med 363: 1313-23 (2010)
PM ID: 20879880 PMC2993160 NIHMS246674
176: Beaty O, Berg S, Blaney S, Malogolowkin M, Krailo M, Knight R, Schaiquevich P, Stewart C, Chen Z, Nelson M, Voss S, Ivy SP, Adamson PC
A phase II trial and pharmacokinetic study of oxaliplatin in children with refractory solid tumors: a Children's Oncology Group study.
Pediatr Blood Cancer 55: 440-5 (2010)
PM ID: 20658614
177: Grimminger PP, Schneider PM, Metzger R, Vallböhmer D, Hölscher AH, Danenberg PV, Brabender J
Low thymidylate synthase, thymidine phosphorylase, and dihydropyrimidine dehydrogenase mRNA expression correlate with prolonged survival in resected non-small-cell lung cancer.
Clin Lung Cancer 11: 328-34 (2010)
PM ID: 20837458
178: Grimminger PP, Schneider PM, Metzger R, Vallböhmer D, Danenberg KD, Danenberg PV, Hölscher AH, Brabender J
The prognostic role of Bcl-2 mRNA expression in curatively resected non-small cell lung cancer (NSCLC).
Lung Cancer 70: 82-7 (2010)
PM ID: 20064672
179: Cai W, Maldonado NV, Cui W, Harutyunyan N, Ji L, Sposto R, Reynolds CP, Keshelava N
Activity of irinotecan and temozolomide in the presence of O6-methylguanine-DNA methyltransferase inhibition in neuroblastoma pre-clinical models.
Br J Cancer 103: 1369-79 (2010)
PM ID: 20924375 PMC2990610
180: Ramkumar K, Serrao E, Odde S, Neamati N
HIV-1 integrase inhibitors: 2007-2008 update.
Med Res Rev 30: 890-954 (2010)
PM ID: 20135632
181: Mori R, Dorff TB, Xiong S, Tarabolous CJ, Ye W, Groshen S, Danenberg KD, Danenberg PV, Pinski JK
The relationship between proangiogenic gene expression levels in prostate cancer and their prognostic value for clinical outcomes.
Prostate 70: 1692-700 (2010)
PM ID: 20564320
182: Shusterman S, London WB, Gillies SD, Hank JA, Voss SD, Seeger RC, Reynolds CP, Kimball J, Albertini MR, Wagner B, Gan J, Eickhoff J, DeSantes KB, Cohn SL, Hecht T, Gadbaw B, Reisfeld RA, Maris JM, Sondel PM
Antitumor activity of hu14.18-IL2 in patients with relapsed/refractory neuroblastoma: a Children's Oncology Group (COG) phase II study.
J Clin Oncol 28: 4969-75 (2010)
PM ID: 20921469 PMC3020698
183: Hadi V, Koh YH, Sanchez TW, Barrios D, Neamati N, Jung KW
Development of the next generation of HIV-1 integrase inhibitors: pyrazolone as a novel inhibitor scaffold.
Bioorg Med Chem Lett 20: 6854-7 (2010)
PM ID: 20864343 PMC2957562 NIHMS229647
184: Parekh C, Jubran R, Erdreich-Epstein A, Panigrahy A, Bluml S, Finlay J, Dhall G
Erratum to: Treatment of children with recurrent high grade gliomas with a bevacizumab containing regimen.
J Neurooncol : (2010)
PM ID: 21110216
185: Rutkowski S, von Hoff K, Emser A, Zwiener I, Pietsch T, Figarella-Branger D, Giangaspero F, Ellison DW, Garre ML, Biassoni V, Grundy RG, Finlay JL, Dhall G, Raquin MA, Grill J
Survival and prognostic factors of early childhood medulloblastoma: an international meta-analysis.
J Clin Oncol 28: 4961-8 (2010)
PM ID: 20940197
186: Chen HJ, Panigrahy A, Dhall G, Finlay JL, Nelson MD, Blüml S
Apparent diffusion and fractional anisotropy of diffuse intrinsic brain stem gliomas.
AJNR Am J Neuroradiol 31: 1879-85 (2010)
PM ID: 20595371
187: Bernstein I, Byun HM, Mohrbacher A, Douer D, Gorospe G, Hergesheimer J, Groshen S, O'Connell C, Yang AS
A phase I biological study of azacitidine (Vidaza™) to determine the optimal dose to inhibit DNA methylation.
Epigenetics 5: 750-7 (2010)
PM ID: 20861661
188: Pollack IF, Hamilton RL, Sobol RW, Nikiforova MN, Nikiforov YE, Lyons-Weiler MA, Laframboise WA, Burger PC, Brat DJ, Rosenblum MK, Gilles FH, Yates AJ, Zhou T, Cohen KJ, Finlay JL, Jakacki RI, Children's Oncology Group
Mismatch repair deficiency is an uncommon mechanism of alkylator resistance in pediatric malignant gliomas: a report from the Children's Oncology Group.
Pediatr Blood Cancer 55: 1066-71 (2010)
PM ID: 20589656 PMC3036982 NIHMS270263
189: Debnath B, Al-Mawsawi LQ, Neamati N
Are we living in the end of the blockbuster drug era?
Drug News Perspect 23: 670-84 (2010)
PM ID: 21180653
190: Dhall G, Khatua S, Finlay JL
Pineal region tumors in children.
Curr Opin Neurol 23: 576-82 (2010)
PM ID: 21042218
191: Venkatramani R, Ma NS, Pitukcheewanont P, Malogolowkin MH, Mascarenhas L
Gorham's disease and diffuse lymphangiomatosis in children and adolescents.
Pediatr Blood Cancer : (2010)
PM ID: 21181877
192: Gupta AA, Gerstle JT, Ng V, Wong A, Fecteau A, Malogolowkin MH, Meyers RL, Grant D, Grant RM
Critical review of controversial issues in the management of advanced pediatric liver tumors.
Pediatr Blood Cancer : (2010)
PM ID: 21125617
193: Gandara DR, Grimminger P, Mack PC, Lara PN, Li T, Danenberg PV, Danenberg KD
Association of epidermal growth factor receptor activating mutations with low ERCC1 gene expression in non-small cell lung cancer.
J Thorac Oncol 5: 1933-8 (2010)
PM ID: 20975603
194: Millard M, Pathania D, Grande F, Xu S, Neamati N
Small-molecule inhibitors of p53-MDM2 interaction: the 2006-2010 update.
Curr Pharm Des 17: 536-59 (2011)
PM ID: 21391905
195: Sands SA, Pasichow KP, Weiss R, Garvin J, Gardner S, Dunkel IJ, Finlay JL
Quality of life and behavioral follow-up study of Head Start I pediatric brain tumor survivors.
J Neurooncol 101: 287-95 (2011)
PM ID: 20526792
196: Grimminger CM, Danenberg PV
Update of prognostic and predictive biomarkers in oropharyngeal squamous cell carcinoma: a review.
Eur Arch Otorhinolaryngol 268: 5-16 (2011)
PM ID: 20827554
197: Al-Mawsawi LQ, Neamati N
Allosteric Inhibitor Development Targeting HIV-1 Integrase.
ChemMedChem : (2011)
PM ID: 21229520
198: Sun X, Yan Y, Liu S, Cao Q, Yang M, Neamati N, Shen B, Niu G, Chen X
18F-FPPRGD2 and 18F-FDG PET of response to Abraxane therapy.
J Nucl Med 52: 140-6 (2011)
PM ID: 21149494
199: Choi SH, Heo K, Byun HM, An W, Lu W, Yang AS
Identification of preferential target sites for human DNA methyltransferases.
Nucleic Acids Res 39: 104-18 (2011)
PM ID: 20841325 PMC3017615
200: Iqbal S, Tsao-Wei DD, Quinn DI, Gitlitz BJ, Groshen S, Aparicio A, Lenz HJ, El-Khoueiry A, Pinski J, Garcia AA
Phase I clinical trial of pegylated liposomal Doxorubicin and docetaxel in patients with advanced solid tumors.
Am J Clin Oncol 34: 27-31 (2011)
PM ID: 20142723
201: Al-Mawsawi LQ, Neamati N
Allosteric inhibitor development targeting HIV-1 integrase.
ChemMedChem 6: 228-41 (2011)
PM ID: 21275045 PMC3115487 NIHMS267684
202: Sharma H, Patil S, Sanchez TW, Neamati N, Schinazi RF, Buolamwini JK
Synthesis, biological evaluation and 3D-QSAR studies of 3-keto salicylic acid chalcones and related amides as novel HIV-1 integrase inhibitors.
Bioorg Med Chem 19: 2030-45 (2011)
PM ID: 21371895
203: Stanford SM, Krishnamurthy D, Falk MD, Messina R, Debnath B, Li S, Liu T, Kazemi R, Dahl R, He Y, Yu X, Chan AC, Zhang ZY, Barrios AM, Woods VL, Neamati N, Bottini N
Discovery of a novel series of inhibitors of lymphoid tyrosine phosphatase with activity in human T cells.
J Med Chem 54: 1640-54 (2011)
PM ID: 21341673 PMC3086468 NIHMS276264
204: Yamada R, Cao X, Butkevich AN, Millard M, Odde S, Mordwinkin N, Gundla R, Zandi E, Louie SG, Petasis NA, Neamati N
Discovery and preclinical evaluation of a novel class of cytotoxic propynoic acid carbamoyl methyl amides (PACMAs).
J Med Chem 54: 2902-14 (2011)
PM ID: 21443194
205: Bacchi A, Carcelli M, Compari C, Fisicaro E, Pala N, Rispoli G, Rogolino D, Sanchez TW, Sechi M, Neamati N
HIV-1 IN strand transfer chelating inhibitors: a focus on metal binding.
Mol Pharm 8: 507-19 (2011)
PM ID: 21323359
206: Venkatramani R, Ma NS, Pitukcheewanont P, Malogolowkin MH, Mascarenhas L
Gorham's disease and diffuse lymphangiomatosis in children and adolescents.
Pediatr Blood Cancer 56: 667-70 (2011)
PM ID: 21298758
207: Khatua S, Phillips A, Fangusaro J, Bovan S, Dhall G, Finlay JL
Recurrent pure CNS germinoma with markedly elevated serum and cerebrospinal fluid human chorionic gonadotropin-beta (HCGβ).
Pediatr Blood Cancer 56: 863-4 (2011)
PM ID: 20949592
208: Grimminger PP, Danenberg P, Dellas K, Arnold D, Rödel C, Machiels JP, Haustermans K, Debucquoy A, Velenik V, Sempoux C, Bracko M, Hölscher AH, Semrau R, Yang D, Danenberg K, Lenz HJ, Vallböhmer D
Biomarkers for cetuximab-based neoadjuvant radiochemotherapy in locally advanced rectal cancer.
Clin Cancer Res 17: 3469-77 (2011)
PM ID: 21558395
209: Villani A, Tabori U, Schiffman J, Shlien A, Beyene J, Druker H, Novokmet A, Finlay J, Malkin D
Biochemical and imaging surveillance in germline TP53 mutation carriers with Li-Fraumeni syndrome: a prospective observational study.
Lancet Oncol 12: 559-67 (2011)
PM ID: 21601526
210: Dhall G, Traverso M, Finlay JL, Shane L, Gonzalez-Gomez I, Jubran R
The role of chemotherapy in pediatric clival chordomas.
J Neurooncol 103: 657-62 (2011)
PM ID: 21052774
211: Parekh C, Jubran R, Erdreich-Epstein A, Panigrahy A, Bluml S, Finlay J, Dhall G
Treatment of children with recurrent high grade gliomas with a bevacizumab containing regimen.
J Neurooncol 103: 673-80 (2011)
PM ID: 21038110
212: Gupta AA, Gerstle JT, Ng V, Wong A, Fecteau A, Malogolowkin MH, Meyers RL, Grant D, Grant RM
Critical review of controversial issues in the management of advanced pediatric liver tumors.
Pediatr Blood Cancer 56: 1013-8 (2011)
PM ID: 21488153
213: Wu Z, Todorov I, Li L, Bading JR, Li Z, Nair I, Ishiyama K, Colcher D, Conti PE, Fraser SE, Shively JE, Kandeel F
In vivo imaging of transplanted islets with 64Cu-DO3A-VS-Cys40-Exendin-4 by targeting GLP-1 receptor.
Bioconjug Chem 22: 1587-94 (2011)
PM ID: 21692471
214: Malogolowkin MH, Katzenstein HM, Meyers RL, Krailo MD, Rowland JM, Haas J, Finegold MJ
Complete surgical resection is curative for children with hepatoblastoma with pure fetal histology: a report from the Children's Oncology Group.
J Clin Oncol 29: 3301-6 (2011)
PM ID: 21768450 PMC3158601
215: Fan X, Zhang FH, Al-Safi RI, Zeng LF, Shabaik Y, Debnath B, Sanchez TW, Odde S, Neamati N, Long YQ
Design of HIV-1 integrase inhibitors targeting the catalytic domain as well as its interaction with LEDGF/p75: a scaffold hopping approach using salicylate and catechol groups.
Bioorg Med Chem 19: 4935-52 (2011)
PM ID: 21778063 PMC3163123 NIHMS308124
216: Birkhahn M, Penson DF, Cai J, Groshen S, Stein JP, Lieskovsky G, Skinner DG, Cote RJ
Long-term outcome in patients with a Gleason score ≤ 6 prostate cancer treated by radical prostatectomy.
BJU Int 108: 660-4 (2011)
PM ID: 21223479
217: O'Neil S, Ji L, Buranahirun C, Azoff J, Dhall G, Khatua S, Patel S, Panigrahy A, Borchert M, Sposto R, Finlay J
Neurocognitive outcomes in pediatric and adolescent patients with central nervous system germinoma treated with a strategy of chemotherapy followed by reduced-dose and volume irradiation.
Pediatr Blood Cancer 57: 669-73 (2011)
PM ID: 21495164
218: Monserrat JP, Al-Safi RI, Tiwari KN, Quentin L, Chabot GG, Vessières A, Jaouen G, Neamati N, Hillard EA
Ferrocenyl chalcone difluoridoborates inhibit HIV-1 integrase and display low activity towards cancer and endothelial cells.
Bioorg Med Chem Lett 21: 6195-7 (2011)
PM ID: 21889342
219: Blüml S, Panigrahy A, Laskov M, Dhall G, Krieger MD, Nelson MD, Finlay JL, Gilles FH
Elevated citrate in pediatric astrocytomas with malignant progression.
Neuro Oncol 13: 1107-17 (2011)
PM ID: 21771868 PMC3177657
220: Fang H, Harned TM, Kalous O, Maldonado V, Declerck YA, Reynolds CP
Synergistic activity of fenretinide and the Bcl-2 family protein inhibitor ABT-737 against human neuroblastoma.
Clin Cancer Res 17: 7093-104 (2011)
PM ID: 21933888
221: Villablanca JG, London WB, Naranjo A, McGrady P, Ames MM, Reid JM, McGovern RM, Buhrow SA, Jackson H, Stranzinger E, Kitchen BJ, Sondel PM, Parisi MT, Shulkin B, Yanik GA, Cohn SL, Reynolds CP
Phase II study of oral capsular 4-hydroxyphenylretinamide (4-HPR/fenretinide) in pediatric patients with refractory or recurrent neuroblastoma: a report from the Children's Oncology Group.
Clin Cancer Res 17: 6858-66 (2011)
PM ID: 21908574 PMC3207022 NIHMS322852
222: Bacchi A, Carcelli M, Compari C, Fisicaro E, Pala N, Rispoli G, Rogolino D, Sanchez TW, Sechi M, Sinisi V, Neamati N
Investigating the role of metal chelation in HIV-1 integrase strand transfer inhibitors.
J Med Chem 54: 8407-20 (2011)
PM ID: 22066494
223: Malogolowkin MH, Katzenstein HM, Krailo M, Meyers RL
Treatment of hepatoblastoma: the North American cooperative group experience.
Front Biosci (Elite Ed) 4: 1717-23 (2012)
PM ID: 22201987
224: Serrao E, Thys W, Demeulemeester J, Al-Mawsawi LQ, Christ F, Debyser Z, Neamati N
A symmetric region of the HIV-1 integrase dimerization interface is essential for viral replication.
PLoS One 7: e45177 (2012)
PM ID: 23028829 PMC3445459
225: Tippin BL, Levine AJ, Materi AM, Song WL, Keku TO, Goodman JE, Sansbury LB, Das S, Dai A, Kwong AM, Lin AM, Lin JM, Park JM, Patterson RE, Chlebowski RT, Garavito RM, Inoue T, Cho W, Lawson JA, Kapoor S, Kolonel LN, Le Marchand L, Haile RW, Sandler RS, Lin HJ
Hematopoietic prostaglandin D synthase (HPGDS): a high stability, Val187Ile isoenzyme common among African Americans and its relationship to risk for colorectal cancer.
Prostaglandins Other Lipid Mediat 97: 22-8 (2012)
PM ID: 21821144 PMC3226866 NIHMS319011
226: Al-Safi RI, Odde S, Shabaik Y, Neamati N
Small-molecule inhibitors of APE1 DNA repair function: an overview.
Curr Mol Pharmacol 5: 14-35 (2012)
PM ID: 22122462
227: Yadav MR, Grande F, Chouhan BS, Naik PP, Giridhar R, Garofalo A, Neamati N
Cytotoxic potential of novel 6,7-dimethoxyquinazolines.
Eur J Med Chem 48: 231-43 (2012)
PM ID: 22209417
228: Cao B, Wang Y, Ding K, Neamati N, Long YQ
Synthesis of the pyridinyl analogues of dibenzylideneacetone (pyr-dba) via an improved Claisen-Schmidt condensation, displaying diverse biological activities as curcumin analogues.
Org Biomol Chem 10: 1239-45 (2012)
PM ID: 22179573
229: Zhang X, Tung CS, Sowa GZ, Hatmal MM, Haworth IS, Qin PZ
Global structure of a three-way junction in a phi29 packaging RNA dimer determined using site-directed spin labeling.
J Am Chem Soc 134: 2644-52 (2012)
PM ID: 22229766 PMC3279945 NIHMS353713
230: Venkatramani R, Dhall G, Patel M, Grimm J, Hawkins C, McComb G, Krieger M, Wong K, O'Neil S, Finlay JL
Supratentorial ependymoma in children: to observe or to treat following gross total resection?
Pediatr Blood Cancer 58: 380-3 (2012)
PM ID: 21370439
231: Sands SA, Zhou T, O'Neil SH, Patel SK, Allen J, McGuire Cullen P, Kaleita TA, Noll R, Sklar C, Finlay JL
Long-term follow-up of children treated for high-grade gliomas: children's oncology group L991 final study report.
J Clin Oncol 30: 943-9 (2012)
PM ID: 22355055 PMC3341107
232: Xu J, Erdreich-Epstein A, Gonzalez-Gomez I, Melendez EY, Smbatyan G, Moats RA, Rosol M, Biegel JA, Reynolds CP
Novel cell lines established from pediatric brain tumors.
J Neurooncol 107: 269-80 (2012)
PM ID: 22120608 PMC3379550 NIHMS380597
233: Gilsanz V, Hu HH, Smith ML, Goodarzian F, Carcich SL, Warburton NM, Malogolowkin M
The depiction of brown adipose tissue is related to disease status in pediatric patients with lymphoma.
AJR Am J Roentgenol 198: 909-13 (2012)
PM ID: 22451560
234: Strother DR, London WB, Schmidt ML, Brodeur GM, Shimada H, Thorner P, Collins MH, Tagge E, Adkins S, Reynolds CP, Murray K, Lavey RS, Matthay KK, Castleberry R, Maris JM, Cohn SL
Outcome after surgery alone or with restricted use of chemotherapy for patients with low-risk neuroblastoma: results of Children's Oncology Group study P9641.
J Clin Oncol 30: 1842-8 (2012)
PM ID: 22529259 PMC3383182
235: Gozali AE, Britt B, Shane L, Gonzalez I, Gilles F, McComb JG, Krieger MD, Lavey RS, Shlien A, Villablanca JG, Erdreich-Epstein A, Dhall G, Jubran R, Tabori U, Malkin D, Finlay JL
Choroid plexus tumors; management, outcome, and association with the Li-Fraumeni syndrome: the Children's Hospital Los Angeles (CHLA) experience, 1991-2010.
Pediatr Blood Cancer 58: 905-9 (2012)
PM ID: 21990040
236: Orgel E, Jain S, Ji L, Pollick L, Si S, Finlay J, Freyer DR
Hearing loss among survivors of childhood brain tumors treated with an irradiation-sparing approach.
Pediatr Blood Cancer 58: 953-8 (2012)
PM ID: 21796767
237: Puumala SE, Ross JA, Feusner JH, Tomlinson GE, Malogolowkin MH, Krailo MD, Spector LG
Parental infertility, infertility treatment and hepatoblastoma: a report from the Children's Oncology Group.
Hum Reprod 27: 1649-56 (2012)
PM ID: 22473396 PMC3357199
238: Popova AM, Hatmal MM, Frushicheva MP, Price EA, Qin PZ, Haworth IS
Nitroxide sensing of a DNA microenvironment: mechanistic insights from EPR spectroscopy and molecular dynamics simulations.
J Phys Chem B 116: 6387-96 (2012)
PM ID: 22574834 PMC3382087 NIHMS377685
239: Ng TS, Bading JR, Park R, Sohi H, Procissi D, Colcher D, Conti PS, Cherry SR, Raubitschek AA, Jacobs RE
Quantitative, simultaneous PET/MRI for intratumoral imaging with an MRI-compatible PET scanner.
J Nucl Med 53: 1102-9 (2012)
PM ID: 22661534 PMC3552656 NIHMS399293
240: Venkatramani R, Malogolowkin MH, Wang L, Mascarenhas L
Pleuropulmonary blastoma: a single-institution experience.
J Pediatr Hematol Oncol 34: e182-5 (2012)
PM ID: 22584785
241: Bonnin A, Zhang L, Blakely RD, Levitt P
The SSRI citalopram affects fetal thalamic axon responsiveness to netrin-1 in vitro independently of SERT antagonism.
Neuropsychopharmacology 37: 1879-84 (2012)
PM ID: 22414815 PMC3376320
242: Debnath B, Xu S, Neamati N
Small molecule inhibitors of signal transducer and activator of transcription 3 (Stat3) protein.
J Med Chem 55: 6645-68 (2012)
PM ID: 22650325
243: Venkatramani R, Furman WL, Fuchs J, Warmann SW, Malogolowkin MH
Current and future management strategies for relapsed or progressive hepatoblastoma.
Paediatr Drugs 14: 221-32 (2012)
PM ID: 22702740
244: Venkatramani R, Wang L, Malvar J, Dias D, Sposto R, Malogolowkin MH, Mascarenhas L
Tumor necrosis predicts survival following neo-adjuvant chemotherapy for hepatoblastoma.
Pediatr Blood Cancer 59: 493-8 (2012)
PM ID: 22190448
245: Rudie JD, Hernandez LM, Brown JA, Beck-Pancer D, Colich NL, Gorrindo P, Thompson PM, Geschwind DH, Bookheimer SY, Levitt P, Dapretto M
Autism-associated promoter variant in MET impacts functional and structural brain networks.
Neuron 75: 904-15 (2012)
PM ID: 22958829 PMC3454529 NIHMS403140
246: Grimminger PP, Shi M, Barrett C, Lebwohl D, Danenberg KD, Brabender J, Vigen CL, Danenberg PV, Winder T, Lenz HJ
TS and ERCC-1 mRNA expressions and clinical outcome in patients with metastatic colon cancer in CONFIRM-1 and -2 clinical trials.
Pharmacogenomics J 12: 404-11 (2012)
PM ID: 21788964
247: Yu S, Zhang L, Yan S, Wang P, Sanchez T, Christ F, Debyser Z, Neamati N, Zhao G
Nitrogen-containing polyhydroxylated aromatics as HIV-1 integrase inhibitors: synthesis, structure-activity relationship analysis, and biological activity.
J Enzyme Inhib Med Chem 27: 628-40 (2012)
PM ID: 22233539
248: Hammock EA, Levitt P
Modulation of parvalbumin interneuron number by developmentally transient neocortical vasopressin receptor 1a (V1aR).
Neuroscience 222: 20-8 (2012)
PM ID: 22820266 PMC3444161 NIHMS395738
249: Grimminger PP, Maus MK, Schneider PM, Metzger R, Hölscher AH, Sugita H, Danenberg PV, Alakus H, Brabender J
Glutathione S-transferase PI (GST-PI) mRNA expression and DNA methylation is involved in the pathogenesis and prognosis of NSCLC.
Lung Cancer 78: 87-91 (2012)
PM ID: 22884253
250: Xu S, Butkevich AN, Yamada R, Zhou Y, Debnath B, Duncan R, Zandi E, Petasis NA, Neamati N
Discovery of an orally active small-molecule irreversible inhibitor of protein disulfide isomerase for ovarian cancer treatment.
Proc Natl Acad Sci U S A 109: 16348-53 (2012)
PM ID: 22988091 PMC3479552
251: Aiello F, Shabaik Y, Esqueda A, Sanchez TW, Grande F, Garofalo A, Neamati N
Design and synthesis of 3-carbamoylbenzoic acid derivatives as inhibitors of human apurinic/apyrimidinic endonuclease 1 (APE1).
ChemMedChem 7: 1825-39 (2012)
PM ID: 22952012
252: Wang Z, Huang P, Bhirde A, Jin A, Ma Y, Niu G, Neamati N, Chen X
A nanoscale graphene oxide-peptide biosensor for real-time specific biomarker detection on the cell surface.
Chem Commun (Camb) 48: 9768-70 (2012)
PM ID: 22919703 PMC3622590 NIHMS455060
253: Perilongo G, Malogolowkin M, Feusner J
Hepatoblastoma clinical research: lessons learned and future challenges.
Pediatr Blood Cancer 59: 818-21 (2012)
PM ID: 22678761
254: Zeng LF, Wang Y, Kazemi R, Xu S, Xu ZL, Sanchez TW, Yang LM, Debnath B, Odde S, Xie H, Zheng YT, Ding J, Neamati N, Long YQ
Repositioning HIV-1 integrase inhibitors for cancer therapeutics: 1,6-naphthyridine-7-carboxamide as a promising scaffold with drug-like properties.
J Med Chem 55: 9492-509 (2012)
PM ID: 23098137
255: Termuhlen AM, Smith LM, Perkins SL, Lones M, Finlay JL, Weinstein H, Gross TG, Abromowitch M
Outcome of newly diagnosed children and adolescents with localized lymphoblastic lymphoma treated on Children's Oncology Group trial A5971: a report from the Children's Oncology Group.
Pediatr Blood Cancer 59: 1229-33 (2012)
PM ID: 22488718
256: Garvin JH, Selch MT, Holmes E, Berger MS, Finlay JL, Flannery A, Goldwein JW, Packer RJ, Rorke-Adams LB, Shiminski-Maher T, Sposto R, Stanley P, Tannous R, Pollack IF, Children's Oncology Group
Phase II study of pre-irradiation chemotherapy for childhood intracranial ependymoma. Children's Cancer Group protocol 9942: a report from the Children's Oncology Group.
Pediatr Blood Cancer 59: 1183-9 (2012)
PM ID: 22949057
257: Aboye TL, Ha H, Majumder S, Christ F, Debyser Z, Shekhtman A, Neamati N, Camarero JA
Design of a novel cyclotide-based CXCR4 antagonist with anti-human immunodeficiency virus (HIV)-1 activity.
J Med Chem 55: 10729-34 (2012)
PM ID: 23151033 PMC3521869 NIHMS422450
258: Debnath B, Xu S, Grande F, Garofalo A, Neamati N
Small molecule inhibitors of CXCR4.
Theranostics 3: 47-75 (2013)
PM ID: 23382786 PMC3563081
259: Shabaik YH, Millard M, Neamati N
Mechanistic evaluation of a novel small molecule targeting mitochondria in pancreatic cancer cells.
PLoS One 8: e54346 (2013)
PM ID: 23349858 PMC3549929
260: Venkatramani R, Malogolowkin M, Davidson TB, May W, Sposto R, Mascarenhas L
A phase I study of vincristine, irinotecan, temozolomide and bevacizumab (vitb) in pediatric patients with relapsed solid tumors.
PLoS One 8: e68416 (2013)
PM ID: 23894304 PMC3718768
261: Ha TC, Spreafico F, Graf N, Dallorso S, Dome JS, Malogolowkin M, Furtwängler R, Hale JP, Moroz V, Machin D, Pritchard-Jones K
An international strategy to determine the role of high dose therapy in recurrent Wilms' tumour.
Eur J Cancer 49: 194-210 (2013)
PM ID: 22959164
262: Carcelli M, Bacchi A, Pelagatti P, Rispoli G, Rogolino D, Sanchez TW, Sechi M, Neamati N
Ruthenium arene complexes as HIV-1 integrase strand transfer inhibitors.
J Inorg Biochem 118: 74-82 (2013)
PM ID: 23123342
263: Torii M, Rakic P, Levitt P
Role of EphA/ephrin--a signaling in the development of topographic maps in mouse corticothalamic projections.
J Comp Neurol 521: 626-37 (2013)
PM ID: 22821544 PMC3511615 [Available on 02/15/14] NIHMS395732 [Available on 02/15/14]
264: Baskin JL, Lezcano E, Kim BS, Figueredo D, Lassaletta A, Perez-Martinez A, Madero L, Caniza MA, Howard SC, Samudio A, Finlay JL
Management of children with brain tumors in Paraguay.
Neuro Oncol 15: 235-41 (2013)
PM ID: 23197688 PMC3548583 [Available on 02/01/14]
265: Sanchez TW, Debnath B, Christ F, Otake H, Debyser Z, Neamati N
Discovery of novel inhibitors of LEDGF/p75-IN protein-protein interactions.
Bioorg Med Chem 21: 957-63 (2013)
PM ID: 23306052
266: Mitra AP, Castelao JE, Hawes D, Tsao-Wei DD, Jiang X, Shi SR, Datar RH, Skinner EC, Stein JP, Groshen S, Yu MC, Ross RK, Skinner DG, Cortessis VK, Cote RJ
Combination of molecular alterations and smoking intensity predicts bladder cancer outcome: a report from the Los Angeles Cancer Surveillance Program.
Cancer 119: 756-65 (2013)
PM ID: 23319010 PMC3565093 [Available on 02/15/14] NIHMS393599 [Available on 02/15/14]
267: Hsieh YT, Gang EJ, Geng H, Park E, Huantes S, Chudziak D, Dauber K, Schaefer P, Scharman C, Shimada H, Shojaee S, Klemm L, Parameswaran R, Loh M, Kang ES, Koo HH, Hofmann WK, Andrade J, Crooks GM, Willman CL, Müschen M, Papayannopoulou T, Heisterkamp N, Bönig H, Kim YM
Integrin alpha4 blockade sensitizes drug resistant pre-B acute lymphoblastic leukemia to chemotherapy.
Blood 121: 1814-8 (2013)
PM ID: 23319569 PMC3591800 [Available on 03/07/14]
268: Torii M, Hackett TA, Rakic P, Levitt P, Polley DB
EphA signaling impacts development of topographic connectivity in auditory corticofugal systems.
Cereb Cortex 23: 775-85 (2013)
PM ID: 22490549 PMC3593572 [Available on 04/01/14]
269: Parekh C, Crooks GM
Critical differences in hematopoiesis and lymphoid development between humans and mice.
J Clin Immunol 33: 711-5 (2013)
PM ID: 23274800 PMC3633618 [Available on 05/01/14] NIHMS432026 [Available on 05/01/14]
270: Rodriguez-Galindo C, Krailo M, Frazier L, Chintagumpala M, Amatruda J, Katzenstein H, Malogolowkin M, Spector L, Pashankar F, Meyers R, Tomlinson G, COG Rare Tumors Disease Committee
Children's Oncology Group's 2013 blueprint for research: rare tumors.
Pediatr Blood Cancer 60: 1016-21 (2013)
PM ID: 23255219
271: Venkatramani R, Ji L, Lasky J, Haley K, Judkins A, Zhou S, Sposto R, Olshefski R, Garvin J, Tekautz T, Kennedy G, Rassekh SR, Moore T, Gardner S, Allen J, Shore R, Moertel C, Atlas M, Dhall G, Finlay J
Outcome of infants and young children with newly diagnosed ependymoma treated on the "Head Start" III prospective clinical trial.
J Neurooncol 113: 285-91 (2013)
PM ID: 23508296
272: Mascarenhas L, Malogolowkin M, Armenian SH, Sposto R, Venkatramani R
A phase I study of oxaliplatin and doxorubicin in pediatric patients with relapsed or refractory extracranial non-hematopoietic solid tumors.
Pediatr Blood Cancer 60: 1103-7 (2013)
PM ID: 23335436
273: Law MJ, Lee DS, Lee CS, Anglim PP, Haworth IS, Laird-Offringa IA
The role of the C-terminal helix of U1A protein in the interaction with U1hpII RNA.
Nucleic Acids Res 41: 7092-100 (2013)
PM ID: 23703211 PMC3737524
274: Ji Y, Majumder S, Millard M, Borra R, Bi T, Elnagar AY, Neamati N, Shekhtman A, Camarero JA
In vivo activation of the p53 tumor suppressor pathway by an engineered cyclotide.
J Am Chem Soc 135: 11623-33 (2013)
PM ID: 23848581 PMC3767463 [Available on 08/07/14] NIHMS510093 [Available on 08/07/14]
275: Zaky W, Dhall G, Ji L, Haley K, Allen J, Atlas M, Bertolone S, Cornelius A, Gardner S, Patel R, Pradhan K, Shen V, Thompson S, Torkildson J, Sposto R, Finlay JL
Intensive induction chemotherapy followed by myeloablative chemotherapy with autologous hematopoietic progenitor cell rescue for young children newly-diagnosed with central nervous system atypical teratoid/rhabdoid tumors: The head start III experience.
Pediatr Blood Cancer : (2013)
PM ID: 23934933
276: Kreissman SG, Seeger RC, Matthay KK, London WB, Sposto R, Grupp SA, Haas-Kogan DA, LaQuaglia MP, Yu AL, Diller L, Buxton A, Park JR, Cohn SL, Maris JM, Reynolds CP, Villablanca JG
Purged versus non-purged peripheral blood stem-cell transplantation for high-risk neuroblastoma (COG A3973): a randomised phase 3 trial.
Lancet Oncol 14: 999-1008 (2013)
PM ID: 23890779
277: Venkatramani R, Malogolowkin MH, Mascarenhas L
Treatment of multiply relapsed wilms tumor with vincristine, irinotecan, temozolomide and bevacizumab.
Pediatr Blood Cancer : (2013)
PM ID: 24115645
278: Wilson PM, Yang D, Azuma M, Shi MM, Danenberg KD, Lebwohl D, Sherrod A, Ladner RD, Zhang W, Danenberg PV, Trarbach T, Folprecht G, Meinhardt G, Lenz HJ
Intratumoral expression profiling of genes involved in angiogenesis in colorectal cancer patients treated with chemotherapy plus the VEGFR inhibitor PTK787/ZK 222584 (vatalanib).
Pharmacogenomics J 13: 410-6 (2013)
PM ID: 22664478
279: Malogolowkin MH, Krailo M, Marina N, Olson T, Frazier AL
Pilot study of cisplatin, etoposide, bleomycin, and escalating dose cyclophosphamide therapy for children with high risk germ cell tumors: a report of the children's oncology group (COG).
Pediatr Blood Cancer 60: 1602-5 (2013)
PM ID: 23703725
280: Maurer BJ, Kang MH, Villablanca JG, Janeba J, Groshen S, Matthay KK, Sondel PM, Maris JM, Jackson HA, Goodarzian F, Shimada H, Czarnecki S, Hasenauer B, Reynolds CP, Marachelian A
Phase I trial of fenretinide delivered orally in a novel organized lipid complex in patients with relapsed/refractory neuroblastoma: a report from the New Approaches to Neuroblastoma Therapy (NANT) consortium.
Pediatr Blood Cancer 60: 1801-8 (2013)
PM ID: 23813912