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USC Norris Comprehensive Cancer Center
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Publications for Norris Cancer Center Members in the Epigenetics and Regulation Program

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Total Number of Publications: 536
Inter Programmatic Publications: 216
Intra Programmatic Publications: 102

1: Kerr KM, Galler JS, Hagen JA, Laird PW, Laird-Offringa IA
The role of DNA methylation in the development and progression of lung adenocarcinoma.
Dis Markers 23: 5-30 (2007)
PM ID: 17325423
2: Alonzo TA, Siegmund KD
Statistical methods for evaluating DNA methylation as a marker for early detection or prognosis.
Dis Markers 23: 113-20 (2007)
PM ID: 17325431
3: An W
Histone acetylation and methylation: combinatorial players for transcriptional regulation.
Subcell Biochem 41: 351-69 (2007)
PM ID: 17484136
4: Jariwala U, Prescott J, Jia L, Barski A, Pregizer S, Cogan JP, Arasheben A, Tilley WD, Scher HI, Gerald WL, Buchanan G, Coetzee GA, Frenkel B
Identification of novel androgen receptor target genes in prostate cancer.
Mol Cancer 6: 39 (2007)
PM ID: 17553165 PMC1904239
5: Zhou D, Zhong S, Ye JJ, Quach KM, Johnson DL, Chen SP
PNRC is a unique nuclear receptor coactivator that stimulates RNA polymerase III-dependent transcription.
J Mol Signal 2: 5 (2007)
PM ID: 17612402 PMC1939705
6: Tsou JA, Galler JS, Siegmund KD, Laird PW, Turla S, Cozen W, Hagen JA, Koss MN, Laird-Offringa IA
Identification of a panel of sensitive and specific DNA methylation markers for lung adenocarcinoma.
Mol Cancer 6: 70 (2007)
PM ID: 17967182 PMC2206053
7: Siegmund KD, Connor CM, Campan M, Long TI, Weisenberger DJ, Biniszkiewicz D, Jaenisch R, Laird PW, Akbarian S
DNA methylation in the human cerebral cortex is dynamically regulated throughout the life span and involves differentiated neurons.
PLoS One 2: e895 (2007)
PM ID: 17878930 PMC1964879
8: Houshdaran S, Cortessis VK, Siegmund K, Yang A, Laird PW, Sokol RZ
Widespread epigenetic abnormalities suggest a broad DNA methylation erasure defect in abnormal human sperm.
PLoS One 2: e1289 (2007)
PM ID: 18074014 PMC2100168
9: Chu MW, Siegmund KD, Eckstam CL, Kim JY, Yang AS, Kanel GC, Tavaré S, Shibata D
Lack of increases in methylation at three CpG-rich genomic loci in non-mitotic adult tissues during aging.
BMC Med Genet 8: 50 (2007)
PM ID: 17672908 PMC1950491
10: Liang C, Feng P, Ku B, Oh BH, Jung JU
UVRAG: a new player in autophagy and tumor cell growth.
Autophagy 3: 69-71 (2007)
PM ID: 17106237
11: Egger G, Aparicio AM, Escobar SG, Jones PA
Inhibition of histone deacetylation does not block resilencing of p16 after 5-aza-2'-deoxycytidine treatment.
Cancer Res 67: 346-53 (2007)
PM ID: 17210717
12: Zhong S, Fromm J, Johnson DL
TBP is differentially regulated by c-Jun N-terminal kinase 1 (JNK1) and JNK2 through Elk-1, controlling c-Jun expression and cell proliferation.
Mol Cell Biol 27: 54-64 (2007)
PM ID: 17074809 PMC1800663
13: Lee YK, Thomas SN, Yang AJ, Ann DK
Doxorubicin down-regulates Kruppel-associated box domain-associated protein 1 sumoylation that relieves its transcription repression on p21WAF1/CIP1 in breast cancer MCF-7 cells.
J Biol Chem 282: 1595-606 (2007)
PM ID: 17079232
14: Shibata D, Tavaré S
Stem cell chronicles: autobiographies within genomes.
Stem Cell Rev 3: 94-103 (2007)
PM ID: 17873386
15: Chen T, Burke KA, Zhan Y, Wang XD, Shibata D, Zhao Y
IL-12 facilitates both the recovery of endogenous hematopoiesis and the engraftment of stem cells after ionizing radiation.
Exp Hematol 35: 203-13 (2007)
PM ID: 17258069
16: Widschwendter M, Fiegl H, Egle D, Mueller-Holzner E, Spizzo G, Marth C, Weisenberger DJ, Campan M, Young JP, Jacobs I, Laird PW
Epigenetic stem cell signature in cancer.
Nat Genet 39: 157-8 (2007)
PM ID: 17200673
17: Lin HH, Xiong YP, Ho YS, Zhou B, Nguyen HV, Deng HT, Lee RH, Yen Y, Borok Z, Ann DK
Transcriptional regulation by targeted expression of architectural transcription factor high mobility group A2 in salivary glands of transgenic mice.
Eur J Oral Sci 115: 30-9 (2007)
PM ID: 17305714
18: Jones PA, Baylin SB
The epigenomics of cancer.
Cell 128: 683-92 (2007)
PM ID: 17320506
19: Botchkareva NV, Kahn M, Ahluwalia G, Shander D
Survivin in the human hair follicle.
J Invest Dermatol 127: 479-82 (2007)
PM ID: 16946715
20: Chen YH, Yang CK, Xia M, Ou CY, Stallcup MR
Role of GAC63 in transcriptional activation mediated by beta-catenin.
Nucleic Acids Res 35: 2084-92 (2007)
PM ID: 17344318
21: Li W, Li YT, Guan S, Fan J, Cheng CF, Bright AM, Chinn C, Chen M, Woodley DT
Extracellular heat shock protein-90alpha: linking hypoxia to skin cell motility and wound healing.
EMBO J 26: 1221-33 (2007)
PM ID: 17304217 PMC1817627
22: Woodley DT, Remington J, Huang Y, Hou Y, Li W, Keene DR, Chen M
Intravenously injected human fibroblasts home to skin wounds, deliver type VII collagen, and promote wound healing.
Mol Ther 15: 628-35 (2007)
PM ID: 17245357
23: Oka K, Oka S, Sasaki T, Ito Y, Bringas P, Nonaka K, Chai Y
The role of TGF-beta signaling in regulating chondrogenesis and osteogenesis during mandibular development.
Dev Biol 303: 391-404 (2007)
PM ID: 17204263 PMC2074881 NIHMS19038
24: Flores-Delgado G, Liu CW, Sposto R, Berndt N
A limited screen for protein interactions reveals new roles for protein phosphatase 1 in cell cycle control and apoptosis.
J Proteome Res 6: 1165-75 (2007)
PM ID: 17274640
25: Miyabayashi T, Teo JL, Yamamoto M, McMillan M, Nguyen C, Kahn M
Wnt/beta-catenin/CBP signaling maintains long-term murine embryonic stem cell pluripotency.
Proc Natl Acad Sci U S A 104: 5668-73 (2007)
PM ID: 17372190 PMC1838514
26: Flodby P, Zhou B, Ann DK, Kim KJ, Minoo P, Crandall ED, Borok Z
Conserved elements within first intron of aquaporin-5 (Aqp5) function as transcriptional enhancers.
Biochem Biophys Res Commun 356: 26-31 (2007)
PM ID: 17339032 PMC2366028 NIHMS20872
27: Zhou B, Ann DK, Li X, Kim KJ, Lin HH, Minoo P, Crandall ED, Borok Z
Hypertonic induction of aquaporin-5: novel role of hypoxia-inducible factor-1alpha.
Am J Physiol Cell Physiol 292: C1280-90 (2007)
PM ID: 17108010
28: Widelitz RB, Veltmaat JM, Mayer JA, Foley J, Chuong CM
Mammary glands and feathers: comparing two skin appendages which help define novel classes during vertebrate evolution.
Semin Cell Dev Biol 18: 255-66 (2007)
PM ID: 17382566
29: Gack MU, Shin YC, Joo CH, Urano T, Liang C, Sun L, Takeuchi O, Akira S, Chen Z, Inoue S, Jung JU
TRIM25 RING-finger E3 ubiquitin ligase is essential for RIG-I-mediated antiviral activity.
Nature 446: 916-920 (2007)
PM ID: 17392790
30: Fu Y, Li JZ, Lee AS
GRP78/BiP inhibits endoplasmic reticulum BIK and protects human breast cancer cells against estrogen starvation-induced apoptosis.
Cancer Res 67: 3734-40 (2007)
PM ID: 17440086
31: Lee AS
GRP78 induction in cancer: therapeutic and prognostic implications.
Cancer Res 67: 3496-9 (2007)
PM ID: 17440054
32: Heo K, Kim BH, Kim KJ, Choi J, Kim HJ, Zhan Y, Ranish JA, An W
Isolation and characterization of proteins associated with histone H3 tails in vivo.
J Biol Chem 282: 15476-83 (2007)
PM ID: 17403666
33: Johnson SS, Zhang C, Fromm J, Willis IM, Johnson DL
Mammalian Maf1 is a negative regulator of transcription by all three nuclear RNA polymerases.
Mol Cell 26: 367-79 (2007)
PM ID: 17499043
34: Chuang JC, Jones PA
Epigenetics and microRNAs.
Pediatr Res 61: 24R-29R (2007)
PM ID: 17413852
35: Driskell RR, Goodheart M, Neff T, Liu XS, Luo MP, Moothart C, Sigmund CD, Hosokawa R, Chai Y, Engelhardt JF
Wnt3a regulates Lef-1 expression during airway submucosal gland morphogenesis.
Dev Biol 305: 90-102 (2007)
PM ID: 17335794 PMC1892170 NIHMS17863
36: Kohonen-Corish MR, Sigglekow ND, Susanto J, Chapuis PH, Bokey EL, Dent OF, Chan CK, Lin BP, Seng TJ, Laird PW, Young JP, Leggett BA, Jass JR, Sutherland RL
Promoter methylation of the mutated in colorectal cancer gene is a frequent early event in colorectal cancer.
Oncogene 26: 4435-41 (2007)
PM ID: 17260021
37: Lee DY, Ianculescu I, Purcell DJ, Zhang XK, Cheng X, Stallcup MR
Surface-scanning mutational analysis of protein arginine methyltransferase 1: roles of specific amino acids in methyltransferase substrate specificity, oligomerization, and coactivator function.
Mol Endocrinol 21: 1381-93 (2007)
PM ID: 17426288 PMC2075475 NIHMS31023
38: Feng Q, Hawes SE, Stern JE, Dem A, Sow PS, Dembele B, Toure P, Sova P, Laird PW, Kiviat NB
Promoter hypermethylation of tumor suppressor genes in urine from patients with cervical neoplasia.
Cancer Epidemiol Biomarkers Prev 16: 1178-84 (2007)
PM ID: 17548682
39: Oka S, Oka K, Xu X, Sasaki T, Bringas P, Chai Y
Cell autonomous requirement for TGF-beta signaling during odontoblast differentiation and dentin matrix formation.
Mech Dev 124: 409-15 (2007)
PM ID: 17449229 PMC2704601 NIHMS25567
40: Ni M, Lee AS
ER chaperones in mammalian development and human diseases.
FEBS Lett 581: 3641-51 (2007)
PM ID: 17481612 PMC2040386 NIHMS28130
41: Yoo CB, Jeong S, Egger G, Liang G, Phiasivongsa P, Tang CK, Redkar S, Jones PA
Delivery of 5-aza-2'-deoxycytidine to cells using oligodeoxynucleotides.
Cancer Res 67: 6400-8 (2007)
PM ID: 17616700
42: Chen HM, Xia M, Lin MW, Yang HT, Kuhlenkamp JF, Li T, Sodir NM, Chen YH, Josef-Lenz H, Laird PW, Clarke S, Mato JM, Lu SC
Role of methionine adenosyltransferase 2A and S-adenosylmethionine in mitogen-induced growth of human colon cancer cells.
Gastroenterology 133: 207-18 (2007)
PM ID: 17631143
43: Jain R, Shaul PW, Borok Z, Willis BC
Endothelin-1 induces alveolar epithelial-mesenchymal transition through endothelin type A receptor-mediated production of TGF-beta1.
Am J Respir Cell Mol Biol 37: 38-47 (2007)
PM ID: 17379848 PMC1899351
44: Wu SK, Trievel RC, Rice JC
Human SFMBT is a transcriptional repressor protein that selectively binds the N-terminal tail of histone H3.
FEBS Lett 581: 3289-96 (2007)
PM ID: 17599839 PMC2045647 NIHMS26798
45: Choi J, Kim BH, Heo K, Kim KJ, Kim HJ, Zhan Y, Ranish JA, An W
Purification and characterization of cellular proteins associated with histone H4 tails.
J Biol Chem 282: 21024-31 (2007)
PM ID: 17548343
46: Fu H, Ishii M, Gu Y, Maxson R
Conditional alleles of Msx1 and Msx2.
Genesis 45: 477-81 (2007)
PM ID: 17654563
47: Chen YH, Ishii M, Sun J, Sucov HM, Maxson RE
Msx1 and Msx2 regulate survival of secondary heart field precursors and post-migratory proliferation of cardiac neural crest in the outflow tract.
Dev Biol 308: 421-37 (2007)
PM ID: 17601530
48: Pemberton TJ, Li FY, Oka S, Mendoza-Fandino GA, Hsu YH, Bringas P, Chai Y, Snead ML, Mehrian-Shai R, Patel PI
Identification of novel genes expressed during mouse tooth development by microarray gene expression analysis.
Dev Dyn 236: 2245-57 (2007)
PM ID: 17626284
49: Siegmund KD, Levine AJ, Chang JL, Laird PW
Modeling exposures for DNA methylation profiles.
Cancer Epidemiol Biomarkers Prev 15: 567-72 (2007)
PM ID: 16537717
50: Prescott J, Jariwala U, Jia L, Cogan JP, Barski A, Pregizer S, Shen HC, Arasheben A, Neilson JJ, Frenkel B, Coetzee GA
Androgen receptor-mediated repression of novel target genes.
Prostate 67: 1371-83 (2007)
PM ID: 17624924
51: Han J, Ishii M, Bringas P, Maas RL, Maxson RE, Chai Y
Concerted action of Msx1 and Msx2 in regulating cranial neural crest cell differentiation during frontal bone development.
Mech Dev 124: 729-45 (2007)
PM ID: 17693062 PMC2220014 NIHMS31781
52: Guan S, Chen M, Woodley DT, Li W
Nckbeta adapter controls neuritogenesis by maintaining the cellular paxillin level.
Mol Cell Biol 27: 6001-11 (2007)
PM ID: 17591694 PMC1952161
53: Willis BC, Borok Z
TGF-beta-induced EMT: mechanisms and implications for fibrotic lung disease.
Am J Physiol Lung Cell Mol Physiol 293: L525-34 (2007)
PM ID: 17631612
54: Bahhady R, Kim KJ, Borok Z, Crandall ED, Shen WC
Enhancement of insulin transport across primary rat alveolar epithelial cell monolayers by endogenous cellular factor(s).
Pharm Res 24: 1713-9 (2007)
PM ID: 17443400
55: Bánhegyi G, Baumeister P, Benedetti A, Dong D, Fu Y, Lee AS, Li JZ, Mao C, Margittai E, Ni M, Paschen W, Piccirella S, Senesi S, Sitia R, Wang M, Yang W
Endoplasmic reticulum stress.
Ann N Y Acad Sci 1113: 58-71 (2007)
PM ID: 17483206
56: Daneshmand S, Quek ML, Lin E, Lee C, Cote RJ, Hawes D, Cai J, Groshen S, Lieskovsky G, Skinner DG, Lee AS, Pinski J
Glucose-regulated protein GRP78 is up-regulated in prostate cancer and correlates with recurrence and survival.
Hum Pathol 38: 1547-52 (2007)
PM ID: 17640713
57: Pyrko P, Schönthal AH, Hofman FM, Chen TC, Lee AS
The unfolded protein response regulator GRP78/BiP as a novel target for increasing chemosensitivity in malignant gliomas.
Cancer Res 67: 9809-16 (2007)
PM ID: 17942911
58: Buchanan G, Ricciardelli C, Harris JM, Prescott J, Yu ZC, Jia L, Butler LM, Marshall VR, Scher HI, Gerald WL, Coetzee GA, Tilley WD
Control of androgen receptor signaling in prostate cancer by the cochaperone small glutamine rich tetratricopeptide repeat containing protein alpha.
Cancer Res 67: 10087-96 (2007)
PM ID: 17942943
59: Takahashi Y, Coppola D, Matsushita N, Cualing HD, Sun M, Sato Y, Liang C, Jung JU, Cheng JQ, Mulé JJ, Pledger WJ, Wang HG
Bif-1 interacts with Beclin 1 through UVRAG and regulates autophagy and tumorigenesis.
Nat Cell Biol 9: 1142-51 (2007)
PM ID: 17891140 PMC2254521 NIHMS40063
60: Kern SE, Shibata D
The fuzzy math of solid tumor stem cells: a perspective.
Cancer Res 67: 8985-8 (2007)
PM ID: 17908998
61: Tsou JA, Galler JS, Wali A, Ye W, Siegmund KD, Groshen S, Laird PW, Turla S, Koss MN, Pass HI, Laird-Offringa IA
DNA methylation profile of 28 potential marker loci in malignant mesothelioma.
Lung Cancer 58: 220-30 (2007)
PM ID: 17659810 PMC2752414 NIHMS33001
62: Lin JC, Jeong S, Liang G, Takai D, Fatemi M, Tsai YC, Egger G, Gal-Yam EN, Jones PA
Role of nucleosomal occupancy in the epigenetic silencing of the MLH1 CpG island.
Cancer Cell 12: 432-44 (2007)
PM ID: 17996647
63: Miranda TB, Jones PA
DNA methylation: the nuts and bolts of repression.
J Cell Physiol 213: 384-90 (2007)
PM ID: 17708532
64: Stern MC, Conti DV, Siegmund KD, Corral R, Yuan JM, Koh WP, Yu MC
DNA repair single-nucleotide polymorphisms in colorectal cancer and their role as modifiers of the effect of cigarette smoking and alcohol in the Singapore Chinese Health Study.
Cancer Epidemiol Biomarkers Prev 16: 2363-72 (2007)
PM ID: 18006925
65: Byun HM, Wong HL, Birnstein EA, Wolff EM, Liang G, Yang AS
Examination of IGF2 and H19 loss of imprinting in bladder cancer.
Cancer Res 67: 10753-8 (2007)
PM ID: 18006818
66: Jensky NE, Sims JK, Rice JC, Dreyer HC, Schroeder ET
The influence of eccentric exercise on mRNA expression of skeletal muscle regulators.
Eur J Appl Physiol 101: 473-80 (2007)
PM ID: 17661068
67: George B, Datar RH, Wu L, Cai J, Patten N, Beil SJ, Groshen S, Stein J, Skinner D, Jones PA, Cote RJ
p53 gene and protein status: the role of p53 alterations in predicting outcome in patients with bladder cancer.
J Clin Oncol 25: 5352-8 (2007)
PM ID: 18048815
68: Poynter JN, Figueiredo JC, Conti DV, Kennedy K, Gallinger S, Siegmund KD, Casey GR, Thibodeau SN, Jenkins MA, Hopper JL, Byrnes GB, Baron JA, Goode EL, Tiirikainen M, Lindor NM, Grove J, Newcomb P, Jass J, Young JP, Potter JD, Haile RW, Duggan DJ, Le Marchand L, Colon CFR
Variants on 9p24 and 8q24 are associated with risk of colorectal cancer: results from the Colon Cancer Family Registry.
Cancer Res 67: 11128-32 (2007)
PM ID: 18056436
69: Liu Z, Choi SW, Crott JW, Keyes MK, Jang H, Smith DE, Kim MH, Laird PW, Bronson R, Mason JB
Mild depletion of dietary folate combined with other B vitamins alters multiple components of the Wnt pathway in mouse colon.
J Nutr 137: 2701-8 (2007)
PM ID: 18029487
70: Ko SO, Chung IH, Xu X, Oka S, Zhao H, Cho ES, Deng C, Chai Y
Smad4 is required to regulate the fate of cranial neural crest cells.
Dev Biol 312: 435-47 (2007)
PM ID: 17964566 PMC2704603 NIHMS35782
71: Wasserberg N, Haney M, Petrone P, Ritter MR, Emami C, Rosca J, Siegmund KD, Kaufman HS
Morbid obesity adversely impacts pelvic floor function in females seeking attention for weight loss surgery.
Dis Colon Rectum 50: 2096-103 (2007)
PM ID: 17899277
72: Feng P, Liang C, Shin YC, Xiaofei E, Zhang W, Gravel R, Wu TT, Sun R, Usherwood E, Jung JU
A novel inhibitory mechanism of mitochondrion-dependent apoptosis by a herpesviral protein.
PLoS Pathog 3: e174 (2007)
PM ID: 18069888 PMC2134948
73: Spektor TM, Rice JC
Ring around the genes.
Nat Cell Biol 9: 1343-4 (2007)
PM ID: 18059356
74: Yacobi NR, Phuleria HC, Demaio L, Liang CH, Peng CA, Sioutas C, Borok Z, Kim KJ, Crandall ED
Nanoparticle effects on rat alveolar epithelial cell monolayer barrier properties.
Toxicol In Vitro 21: 1373-81 (2007)
PM ID: 17555923
75: Gal-Yam EN, Saito Y, Egger G, Jones PA
Cancer epigenetics: modifications, screening, and therapy.
Annu Rev Med 59: 267-80 (2008)
PM ID: 17937590
76: Yang CK, Kim JH, Ann DK, Stallcup MR
Differential regulation of the two transcriptional activation domains of the coiled-coil coactivator CoCoA by sumoylation.
BMC Mol Biol 9: 12 (2008)
PM ID: 18218142 PMC2263068
77: Maxson R, Ishii M
The Bmp pathway in skull vault development.
Front Oral Biol 12: 197-208 (2008)
PM ID: 18391502
78: Chen YH, Ishii M, Sucov HM, Maxson RE
Msx1 and Msx2 are required for endothelial-mesenchymal transformation of the atrioventricular cushions and patterning of the atrioventricular myocardium.
BMC Dev Biol 8: 75 (2008)
PM ID: 18667074 PMC2518925
79: Siegmund KD, Marjoram P, Shibata D
Modeling DNA methylation in a population of cancer cells.
Stat Appl Genet Mol Biol 7: Article 18 (2008)
PM ID: 18597664
80: Basile LA, Gallaher TK, Shibata D, Miller JD, Douer D
Multilineage hematopoietic recovery with concomitant antitumor effects using low dose Interleukin-12 in myelosuppressed tumor-bearing mice.
J Transl Med 6: 26 (2008)
PM ID: 18489769 PMC2424034
81: Anglim PP, Galler JS, Koss MN, Hagen JA, Turla S, Campan M, Weisenberger DJ, Laird PW, Siegmund KD, Laird-Offringa IA
Identification of a panel of sensitive and specific DNA methylation markers for squamous cell lung cancer.
Mol Cancer 7: 62 (2008)
PM ID: 18616821 PMC2483990
82: Jia L, Berman BP, Jariwala U, Yan X, Cogan JP, Walters A, Chen T, Buchanan G, Frenkel B, Coetzee GA
Genomic androgen receptor-occupied regions with different functions, defined by histone acetylation, coregulators and transcriptional capacity.
PLoS One 3: e3645 (2008)
PM ID: 18997859 PMC2577007
83: Anglim PP, Alonzo TA, Laird-Offringa IA
DNA methylation-based biomarkers for early detection of non-small cell lung cancer: an update.
Mol Cancer 7: 81 (2008)
PM ID: 18947422 PMC2585582
84: Magda D, Lecane PS, Prescott J, Thiemann P, Ma X, Dranchak PK, Toleno DM, Ramaswamy K, Siegmund KD, Hacia JG
mtDNA depletion confers specific gene expression profiles in human cells grown in culture and in xenograft.
BMC Genomics 9: 521 (2008)
PM ID: 18980691 PMC2612029
85: Minoo P, Hu L, Zhu NL, Borok Z, Bellusci S, Groffen J, Kardassis D, Li C
SMAD3 prevents binding of NKX2.1 and FOXA1 to the SpB promoter through its MH1 and MH2 domains.
Nucleic Acids Res 36: 179-88 (2008)
PM ID: 18003659 PMC2248754
86: Dong D, Ni M, Li J, Xiong S, Ye W, Virrey JJ, Mao C, Ye R, Wang M, Pen L, Dubeau L, Groshen S, Hofman FM, Lee AS
Critical role of the stress chaperone GRP78/BiP in tumor proliferation, survival, and tumor angiogenesis in transgene-induced mammary tumor development.
Cancer Res 68: 498-505 (2008)
PM ID: 18199545
87: Plikus MV, Mayer JA, de la Cruz D, Baker RE, Maini PK, Maxson R, Chuong CM
Cyclic dermal BMP signalling regulates stem cell activation during hair regeneration.
Nature 451: 340-4 (2008)
PM ID: 18202659 PMC2696201 NIHMS110153
88: Shibata D
Stem cells as common ancestors in a colorectal cancer ancestral tree.
Curr Opin Gastroenterol 24: 59-63 (2008)
PM ID: 18043234
89: Qiao R, Yan W, Clavijo CA, Mehrian-Shai R, Zhong Q, Kim KJ, Ann DK, Crandall ED, Borok Z
Effects of KGF on alveolar epithelial cell transdifferentiation are mediated by JNK signaling.
Am J Respir Cell Mol Biol 38: 239-46 (2008)
PM ID: 17872496 PMC2214671
90: Shibata D
Mistakes make history: visualizing intestinal tectonics.
Gastroenterology 134: 628-31 (2008)
PM ID: 18242228
91: Kang GH, Lee SY, Cho NY, Gandamihardja TA, Long TI, Weisenberger DJ, Campan M, Laird PW
DNA methylation profiles of gastric carcinoma characterized by quantitative DNA methylation analysis.
Lab Invest 88: 161-70 (2008)
PM ID: 18158559
92: Ku B, Woo JS, Liang C, Lee KH, Hong HS, E X, Kim KS, Jung JU, Oh BH
Structural and biochemical bases for the inhibition of autophagy and apoptosis by viral BCL-2 of murine gamma-herpesvirus 68.
PLoS Pathog 4: e25 (2008)
PM ID: 18248095 PMC2222952
93: Talbot SG, Mehrara BJ, Disa JJ, Wong AK, Pusic A, Cordeiro PG, Athanasian EA
Soft-tissue coverage of the hand following sarcoma resection.
Plast Reconstr Surg 121: 534-43 (2008)
PM ID: 18300973
94: Hacia JG, Lee CC, Jimenez DF, Karaman MW, Ho VV, Siegmund KD, Tarantal AF
Age-related gene expression profiles of rhesus monkey bone marrow-derived mesenchymal stem cells.
J Cell Biochem 103: 1198-210 (2008)
PM ID: 17685434
95: Bates SR, Tao JQ, Yu KJ, Borok Z, Crandall ED, Collins HL, Rothblat GH
Expression and biological activity of ABCA1 in alveolar epithelial cells.
Am J Respir Cell Mol Biol 38: 283-92 (2008)
PM ID: 17884990 PMC2258448
96: Collins RE, Northrop JP, Horton JR, Lee DY, Zhang XK, Stallcup MR, Cheng X
The ankyrin repeats of G9a and GLP histone methyltransferases are mono- and dimethyllysine binding modules.
Nat Struct Mol Biol 15: 245-50 (2008)
PM ID: 18264113 PMC2586904 NIHMS75647
97: Miller AJ, Dudley SD, Tsao JL, Shibata D, Liskay RM
Tractable Cre-lox system for stochastic alteration of genes in mice.
Nat Methods 5: 227-9 (2008)
PM ID: 18264106 PMC2394730 NIHMS49371
98: Uchiyama T, Fujita T, Gukasyan HJ, Kim KJ, Borok Z, Crandall ED, Lee VH
Functional characterization and cloning of amino acid transporter B(0,+) (ATB(0,+)) in primary cultured rat pneumocytes.
J Cell Physiol 214: 645-54 (2008)
PM ID: 17960566
99: Pohl A, Lurje G, Kahn M, Lenz HJ
Stem cells in colon cancer.
Clin Colorectal Cancer 7: 92-8 (2008)
PM ID: 18501067
100: Schönmeyr BH, Wong AK, Li S, Gewalli F, Cordiero PG, Mehrara BJ
Treatment of hydroxyapatite scaffolds with fibronectin and fetal calf serum increases osteoblast adhesion and proliferation in vitro.
Plast Reconstr Surg 121: 751-62 (2008)
PM ID: 18317125
101: Takamori K, Hosokawa R, Xu X, Deng X, Bringas P, Chai Y
Epithelial fibroblast growth factor receptor 1 regulates enamel formation.
J Dent Res 87: 238-43 (2008)
PM ID: 18296607
102: Kim KJ, Choi J, Heo K, Kim HJ, Levens D, Kohno K, Johnson EM, Brock HW, An W
Isolation and characterization of a novel H1.2 complex that acts as a repressor of p53-mediated transcription.
J Biol Chem 283: 9113-26 (2008)
PM ID: 18258596 PMC2431041
103: Heo K, Kim HJ, Choi SH, Choi J, Kim KJ, Gu J, Lieber MR, Yang AS, An W
FACT-mediated exchange of histone variant H2AX regulated by phosphorylation of H2AX and ADP-ribosylation of Spt16.
Mol Cell 30: 86-97 (2008)
PM ID: 18406329
104: Johnson DL, Johnson SA
Cell biology. RNA metabolism and oncogenesis.
Science 320: 461-2 (2008)
PM ID: 18436765
105: Wong AK, Schonmeyr B, Schonmyer BH, Schonmeyer BH, Singh P, Carlson DL, Li S, Mehrara BJ
Histologic analysis of angiogenesis and lymphangiogenesis in acellular human dermis.
Plast Reconstr Surg 121: 1144-52 (2008)
PM ID: 18349631
106: Pike BL, Greiner TC, Wang X, Weisenburger DD, Hsu YH, Renaud G, Wolfsberg TG, Kim M, Weisenberger DJ, Siegmund KD, Ye W, Groshen S, Mehrian-Shai R, Delabie J, Chan WC, Laird PW, Hacia JG
DNA methylation profiles in diffuse large B-cell lymphoma and their relationship to gene expression status.
Leukemia 22: 1035-43 (2008)
PM ID: 18288132 PMC2654231 NIHMS97202
107: Cheng CF, Fan J, Fedesco M, Guan S, Li YT, Bandyopadhyay B, Bright AM, Yerushalmi D, Liang M, Chen M, Han YP, Woodley DT, Li W
Transforming growth factor alpha (TGFalpha)-stimulated secretion of HSP90alpha: using the receptor LRP-1/CD91 to promote human skin cell migration against a TGFbeta-rich environment during wound healing.
Mol Cell Biol 28: 3344-58 (2008)
PM ID: 18332123 PMC2423165
108: Ku B, Woo JS, Liang C, Lee KH, Jung JU, Oh BH
An insight into the mechanistic role of Beclin 1 and its inhibition by prosurvival Bcl-2 family proteins.
Autophagy 4: 519-20 (2008)
PM ID: 18334862
109: Gopalakrishna R, Gundimeda U, Schiffman JE, McNeill TH
A direct redox regulation of protein kinase C isoenzymes mediates oxidant-induced neuritogenesis in PC12 cells.
J Biol Chem 283: 14430-44 (2008)
PM ID: 18375950 PMC2386917 NIHMS48661
110: Zhou B, Zhong Q, Minoo P, Li C, Ann DK, Frenkel B, Morrisey EE, Crandall ED, Borok Z
Foxp2 inhibits Nkx2.1-mediated transcription of SP-C via interactions with the Nkx2.1 homeodomain.
Am J Respir Cell Mol Biol 38: 750-8 (2008)
PM ID: 18239190 PMC2396252
111: Patel LN, Uchiyama T, Kim KJ, Borok Z, Crandall ED, Shen WC, Lee VH
Molecular and functional expression of multidrug resistance-associated protein-1 in primary cultured rat alveolar epithelial cells.
J Pharm Sci 97: 2340-9 (2008)
PM ID: 17854063
112: Yacobi NR, Demaio L, Xie J, Hamm-Alvarez SF, Borok Z, Kim KJ, Crandall ED
Polystyrene nanoparticle trafficking across alveolar epithelium.
Nanomedicine 4: 139-45 (2008)
PM ID: 18375191
113: Chu MW, Siegmund KD, Hao QL, Crooks GM, Tavaré S, Shibata D
Inferring relative numbers of human leucocyte genome replications.
Br J Haematol 141: 862-71 (2008)
PM ID: 18410448
114: Woiwode A, Johnson SA, Zhong S, Zhang C, Roeder RG, Teichmann M, Johnson DL
PTEN represses RNA polymerase III-dependent transcription by targeting the TFIIIB complex.
Mol Cell Biol 28: 4204-14 (2008)
PM ID: 18391023 PMC2423115
115: Woodley DT, Hou Y, Martin SE, Li W, Chen M
Characterization of molecular mechanisms underlying mutations in dystrophic epidermolysis bullosa using site-directed mutagenesis.
J Biol Chem 283: 17838-45 (2008)
PM ID: 18450758 PMC2440610
116: Johnson SA, Dubeau L, Johnson DL
Enhanced RNA polymerase III-dependent transcription is required for oncogenic transformation.
J Biol Chem 283: 19184-91 (2008)
PM ID: 18456653 PMC2443659
117: Liang C, E X, Jung JU
Downregulation of autophagy by herpesvirus Bcl-2 homologs.
Autophagy 4: 268-72 (2008)
PM ID: 17993780
118: Kalakonda N, Fischle W, Boccuni P, Gurvich N, Hoya-Arias R, Zhao X, Miyata Y, Macgrogan D, Zhang J, Sims JK, Rice JC, Nimer SD
Histone H4 lysine 20 monomethylation promotes transcriptional repression by L3MBTL1.
Oncogene 27: 4293-304 (2008)
PM ID: 18408754 PMC2742506 NIHMS124782
119: Houston SI, McManus KJ, Adams MM, Sims JK, Carpenter PB, Hendzel MJ, Rice JC
Catalytic function of the PR-Set7 histone H4 lysine 20 monomethyltransferase is essential for mitotic entry and genomic stability.
J Biol Chem 283: 19478-88 (2008)
PM ID: 18480059 PMC2443654
120: Sims JK, Rice JC
PR-Set7 establishes a repressive trans-tail histone code that regulates differentiation.
Mol Cell Biol 28: 4459-68 (2008)
PM ID: 18474616 PMC2447116
121: Yuan JM, Chan KK, Coetzee GA, Castelao JE, Watson MA, Bell DA, Wang RH, Yu MC
Genetic determinants in the metabolism of bladder carcinogens in relation to risk of bladder cancer.
Carcinogenesis 29: 1386-93 (2008)
PM ID: 18544563 PMC2720058 NIHMS104621
122: Zhou B, Ann DK, Flodby P, Minoo P, Liebler JM, Crandall ED, Borok Z
Rat aquaporin-5 4.3-kb 5'-flanking region differentially regulates expression in salivary gland and lung in vivo.
Am J Physiol Cell Physiol 295: C111-20 (2008)
PM ID: 18448628 PMC2493550
123: Liang C, Lee JS, Inn KS, Gack MU, Li Q, Roberts EA, Vergne I, Deretic V, Feng P, Akazawa C, Jung JU
Beclin1-binding UVRAG targets the class C Vps complex to coordinate autophagosome maturation and endocytic trafficking.
Nat Cell Biol 10: 776-87 (2008)
PM ID: 18552835
124: Lyu J, Yamamoto V, Lu W
Cleavage of the Wnt receptor Ryk regulates neuronal differentiation during cortical neurogenesis.
Dev Cell 15: 773-80 (2008)
PM ID: 19000841
125: Schönmeyr BH, Wong AK, Soares M, Fernandez J, Clavin N, Mehrara BJ
Ionizing radiation of mesenchymal stem cells results in diminution of the precursor pool and limits potential for multilineage differentiation.
Plast Reconstr Surg 122: 64-76 (2008)
PM ID: 18594388
126: Chen HM, Zhuang FF, Liu YH, Xu B, Del Moral PM, Deng WT, Chai Y, Kolb M, Gauldie J, Warburton D, Moses HL, Shi W
TGF-beta receptor II in epithelia versus mesenchyme plays distinct roles in the developing lung.
Eur Respir J 32: 285-95 (2008)
PM ID: 18321928
127: Cheng CF, Fan J, Bandyopahdhay B, Mock D, Guan S, Chen M, Woodley DT, Li W
Profiling motility signal-specific genes in primary human keratinocytes.
J Invest Dermatol 128: 1981-90 (2008)
PM ID: 18323786
128: Bahhady R, Kim KJ, Borok Z, Crandall ED, Shen WC
Characterization of protein factor(s) in rat bronchoalveolar lavage fluid that enhance insulin transport via transcytosis across primary rat alveolar epithelial cell monolayers.
Eur J Pharm Biopharm 69: 808-16 (2008)
PM ID: 18406118
129: Weisenberger DJ, Trinh BN, Campan M, Sharma S, Long TI, Ananthnarayan S, Liang G, Esteva FJ, Hortobagyi GN, McCormick F, Jones PA, Laird PW
DNA methylation analysis by digital bisulfite genomic sequencing and digital MethyLight.
Nucleic Acids Res 36: 4689-98 (2008)
PM ID: 18628296 PMC2504308
130: Sir D, Liang C, Chen WL, Jung JU, Ou JH
Perturbation of autophagic pathway by hepatitis C virus.
Autophagy 4: 830-1 (2008)
PM ID: 18635950 PMC2574555 NIHMS60148
131: Liang C, Sir D, Lee SY, Ou JH, Jung JU
Beyond autophagy: the role of UVRAG in membrane trafficking.
Autophagy 4: 817-20 (2008)
PM ID: 18612260
132: Byun HM, Choi SH, Laird PW, Trinh BN, Siddiqui MA, Marquez VE, Yang AS
2'-Deoxy-N4-[2-(4-nitrophenyl)ethoxycarbonyl]-5-azacytidine: a novel inhibitor of DNA methyltransferase that requires activation by human carboxylesterase 1.
Cancer Lett 266: 238-48 (2008)
PM ID: 18499340 PMC2528876 NIHMS57985
133: Julien KR, Sumita M, Chen PH, Laird-Offringa IA, Hoogstraten CG
Conformationally restricted nucleotides as a probe of structure-function relationships in RNA.
RNA 14: 1632-43 (2008)
PM ID: 18596252 PMC2491483
134: Virrey JJ, Guan S, Li W, Schönthal AH, Chen TC, Hofman FM
Increased survivin expression confers chemoresistance to tumor-associated endothelial cells.
Am J Pathol 173: 575-85 (2008)
PM ID: 18599610 PMC2475793
135: Virrey JJ, Dong D, Stiles C, Patterson JB, Pen L, Ni M, Schönthal AH, Chen TC, Hofman FM, Lee AS
Stress chaperone GRP78/BiP confers chemoresistance to tumor-associated endothelial cells.
Mol Cancer Res 6: 1268-75 (2008)
PM ID: 18708359 PMC2593417 NIHMS72229
136: Xing Y, Li C, Hu L, Tiozzo C, Li M, Chai Y, Bellusci S, Anderson SA, Minoo P
Mechanisms of TGFbeta inhibition of LUNG endodermal morphogenesis: the role of TbetaRII, Smads, Nkx2.1 and Pten.
Dev Biol 320: 340-50 (2008)
PM ID: 18602626 PMC2597224 NIHMS65745
137: Xu X, Han J, Ito Y, Bringas P, Deng C, Chai Y
Ectodermal Smad4 and p38 MAPK are functionally redundant in mediating TGF-beta/BMP signaling during tooth and palate development.
Dev Cell 15: 322-9 (2008)
PM ID: 18694570 PMC2610417 NIHMS66185
138: Liebler JM, Lutzko C, Banfalvi A, Senadheera D, Aghamohammadi N, Crandall ED, Borok Z
Retention of human bone marrow-derived cells in murine lungs following bleomycin-induced lung injury.
Am J Physiol Lung Cell Mol Physiol 295: L285-92 (2008)
PM ID: 18515407 PMC2519849
139: Douglas D, Hsu JH, Hung L, Cooper A, Abdueva D, van Doorninck J, Peng G, Shimada H, Triche TJ, Lawlor ER
BMI-1 promotes ewing sarcoma tumorigenicity independent of CDKN2A repression.
Cancer Res 68: 6507-15 (2008)
PM ID: 18701473 PMC2570201 NIHMS56191
140: Meyer JS, Nadel HR, Marina N, Womer RB, Brown KL, Eary JF, Gorlick R, Grier HE, Randall RL, Lawlor ER, Lessnick SL, Schomberg PJ, Kailo MD
Imaging guidelines for children with Ewing sarcoma and osteosarcoma: a report from the Children's Oncology Group Bone Tumor Committee.
Pediatr Blood Cancer 51: 163-70 (2008)
PM ID: 18454470
141: Marson A, Foreman R, Chevalier B, Bilodeau S, Kahn M, Young RA, Jaenisch R
Wnt signaling promotes reprogramming of somatic cells to pluripotency.
Cell Stem Cell 3: 132-5 (2008)
PM ID: 18682236
142: Kim JH, Yang CK, Heo K, Roeder RG, An W, Stallcup MR
CCAR1, a key regulator of mediator complex recruitment to nuclear receptor transcription complexes.
Mol Cell 31: 510-9 (2008)
PM ID: 18722177 PMC2562329 NIHMS64408
143: Wolff EM, Liang G, Cortez CC, Tsai YC, Castelao JE, Cortessis VK, Tsao-Wei DD, Groshen S, Jones PA
RUNX3 methylation reveals that bladder tumors are older in patients with a history of smoking.
Cancer Res 68: 6208-14 (2008)
PM ID: 18676844 PMC2536768 NIHMS53732
144: American Association for Cancer Research Human Epigenome Task Force(Dr. Jones PA) , American Association for Cancer Research Human Epigenome Task Force(Dr. Laird PW) , European Union, Network of Excellence, Scientific Advisory Board
Moving AHEAD with an international human epigenome project.
Nature 454: 711-5 (2008)
PM ID: 18685699
145: Li JZ, Ni M, Lee B, Barron E, Hinton DR, Lee AS
The unfolded protein response regulator GRP78/BiP is required for endoplasmic reticulum integrity and stress-induced autophagy in mammalian cells.
Cell Death Differ 15: 1460-71 (2008)
PM ID: 18551133 PMC2758056 NIHMS129474
146: Coles EG, Lawlor ER, Bronner-Fraser M
EWS-FLI1 causes neuroepithelial defects and abrogates emigration of neural crest stem cells.
Stem Cells 26: 2237-44 (2008)
PM ID: 18556509
147: Yoo CB, Chuang JC, Byun HM, Egger G, Yang AS, Dubeau L, Long TI, Laird PW, Marquez VE, Jones PA
Long-term epigenetic therapy with oral zebularine has minimal side effects and prevents intestinal tumors in mice.
Cancer Prev Res (Phila Pa) 1: 233-40 (2008)
PM ID: 19138966
148: Gal-Yam EN, Egger G, Iniguez L, Holster H, Einarsson S, Zhang XK, Lin JC, Liang G, Jones PA, Tanay A
Frequent switching of Polycomb repressive marks and DNA hypermethylation in the PC3 prostate cancer cell line.
Proc Natl Acad Sci U S A 105: 12979-84 (2008)
PM ID: 18753622 PMC2529074
149: Lopes EC, Valls E, Figueroa ME, Mazur A, Meng FG, Chiosis G, Laird PW, Schreiber-Agus N, Greally JM, Prokhortchouk E, Melnick A
Kaiso contributes to DNA methylation-dependent silencing of tumor suppressor genes in colon cancer cell lines.
Cancer Res 68: 7258-63 (2008)
PM ID: 18794111
150: Robinson PJ, An W, Routh A, Martino F, Chapman L, Roeder RG, Rhodes D
30 nm chromatin fibre decompaction requires both H4-K16 acetylation and linker histone eviction.
J Mol Biol 381: 816-25 (2008)
PM ID: 18653199
151: Valamehr B, Jonas SJ, Polleux J, Qiao R, Guo S, Gschweng EH, Stiles B, Kam K, Luo TJ, Witte ON, Liu X, Dunn B, Wu H
Hydrophobic surfaces for enhanced differentiation of embryonic stem cell-derived embryoid bodies.
Proc Natl Acad Sci U S A 105: 14459-64 (2008)
PM ID: 18791068 PMC2567159
152: Jiang X, Castelao JE, Groshen S, Cortessis VK, Shibata DK, Conti DV, Gago-Dominguez M
Water intake and bladder cancer risk in Los Angeles County.
Int J Cancer 123: 1649-56 (2008)
PM ID: 18623082
153: Cancer Genome Atlas Research Network
Comprehensive genomic characterization defines human glioblastoma genes and core pathways.
Nature 455: 1061-8 (2008)
PM ID: 18772890 PMC2671642 NIHMS68048
154: Gack MU, Kirchhofer A, Shin YC, Inn KS, Liang C, Cui S, Myong S, Ha TT, Hopfner KP, Jung JU
Roles of RIG-I N-terminal tandem CARD and splice variant in TRIM25-mediated antiviral signal transduction.
Proc Natl Acad Sci U S A 105: 16743-8 (2008)
PM ID: 18948594 PMC2575490
155: Fromm JA, Johnson SA, Johnson DL
Epidermal growth factor receptor 1 (EGFR1) and its variant EGFRvIII regulate TATA-binding protein expression through distinct pathways.
Mol Cell Biol 28: 6483-95 (2008)
PM ID: 18710943 PMC2577416
156: Pregizer S, Baniwal SK, Yan X, Borok Z, Frenkel B
Progressive recruitment of Runx2 to genomic targets despite decreasing expression during osteoblast differentiation.
J Cell Biochem 105: 965-70 (2008)
PM ID: 18821584 PMC2591066 NIHMS75367
157: Zhou B, Francis TA, Yang HT, Tseng W, Zhong Q, Frenkel B, Morrisey EE, Ann DK, Minoo P, Crandall ED, Borok Z
GATA-6 mediates transcriptional activation of aquaporin-5 through interactions with Sp1.
Am J Physiol Cell Physiol 295: C1141-50 (2008)
PM ID: 18768929 PMC2584994
158: Poynter JN, Siegmund KD, Weisenberger DJ, Long TI, Thibodeau SN, Lindor NM, Young JP, Jenkins MA, Hopper JL, Baron JA, Buchanan D, Casey GR, Levine AJ, Le Marchand L, Gallinger S, Bapat B, Potter JD, Newcomb PA, Haile RW, Laird PW, Colon Cancer Family Registry Investigators
Molecular characterization of MSI-H colorectal cancer by MLHI promoter methylation, immunohistochemistry, and mismatch repair germline mutation screening.
Cancer Epidemiol Biomarkers Prev 17: 3208-15 (2008)
PM ID: 18990764 PMC2628332 NIHMS80565
159: McIntosh M, Anderson GL, Drescher C, Hanash S, Urban N, Brown PO, Gambhir SS, Coukos G, Laird PW, Nelson B, Palmer C
Ovarian cancer early detection claims are biased.
Clin Cancer Res 14: 7574; author reply 7577-9 (2008)
PM ID: 18948385
160: Mayer JA, Foley J, de la Cruz D, Chuong CM, Widelitz RB
Conversion of the nipple to hair-bearing epithelia by lowering bone morphogenetic protein pathway activity at the dermal-epidermal interface.
Am J Pathol 173: 1339-48 (2008)
PM ID: 18832580 PMC2570124
161: Cortez CC, Jones PA
Chromatin, cancer and drug therapies.
Mutat Res 647: 44-51 (2008)
PM ID: 18691602 PMC2631123 [Available on 12/01/09] NIHMS81512 [Available on 12/01/09]
162: Khalid O, Baniwal SK, Purcell DJ, Leclerc N, Gabet Y, Stallcup MR, Coetzee GA, Frenkel B
Modulation of Runx2 activity by estrogen receptor-alpha: implications for osteoporosis and breast cancer.
Endocrinology 149: 5984-95 (2008)
PM ID: 18755791 PMC2613062 [Available on 12/01/09]
163: Fu Y, Wey S, Wang M, Ye R, Liao CP, Roy-Burman P, Lee AS
Pten null prostate tumorigenesis and AKT activation are blocked by targeted knockout of ER chaperone GRP78/BiP in prostate epithelium.
Proc Natl Acad Sci U S A 105: 19444-9 (2008)
PM ID: 19033462 PMC2614780
164: Yeung BH, Kwan BW, He QY, Lee AS, Liu JF, Wong AS
Glucose-regulated protein 78 as a novel effector of BRCA1 for inhibiting stress-induced apoptosis.
Oncogene 27: 6782-9 (2008)
PM ID: 18776923
165: Yoo CB, Valente R, Congiatu C, Gavazza F, Angel A, Siddiqui MA, Jones PA, McGuigan C, Marquez VE
Activation of p16 gene silenced by DNA methylation in cancer cells by phosphoramidate derivatives of 2'-deoxyzebularine.
J Med Chem 51: 7593-601 (2008)
PM ID: 19006382 PMC2659950 [Available on 12/11/09] NIHMS90725 [Available on 12/11/09]
166: Li P, Tong C, Mehrian-Shai R, Jia L, Wu N, Yan Y, Maxson RE, Schulze EN, Song H, Hsieh CL, Pera MF, Ying QL
Germline competent embryonic stem cells derived from rat blastocysts.
Cell 135: 1299-310 (2008)
PM ID: 19109898 PMC2735113 NIHMS131481
167: Li M, Li C, Liu YH, Xing Y, Hu L, Borok Z, Kwong KY, Minoo P
Mesodermal deletion of transforming growth factor-beta receptor II disrupts lung epithelial morphogenesis: cross-talk between TGF-beta and Sonic hedgehog pathways.
J Biol Chem 283: 36257-64 (2008)
PM ID: 18990706 PMC2605990 [Available on 12/26/09]
168: Liang C, Lee JS, Jung JU
Immune evasion in Kaposi's sarcoma-associated herpes virus associated oncogenesis.
Semin Cancer Biol 18: 423-36 (2008)
PM ID: 18948197
169: Gundimeda U, Schiffman JE, Chhabra D, Wong J, Wu A, Gopalakrishna R
Locally generated methylseleninic acid induces specific inactivation of protein kinase C isoenzymes: relevance to selenium-induced apoptosis in prostate cancer cells.
J Biol Chem 283: 34519-31 (2008)
PM ID: 18922790
170: Tsou JA, Kazarian M, Patel AV, Galler JS, Laird-Offringa IA, Carpenter CL, London SJ
Low level anti-Hu reactivity: A risk marker for small cell lung cancer?
Cancer Detect Prev 32: 292-9 (2009)
PM ID: 19070439
171: Haiman CA, Garcia RR, Hsu CP, Xia L, Ha H, Sheng X, Le Marchand L, Kolonel LN, Henderson BE, Stallcup MR, Greene GL, Press MF
Screening and association testing of common coding variation in steroid hormone receptor co-activator and co-repressor genes in relation to breast cancer risk: the Multiethnic Cohort.
BMC Cancer 9: 43 (2009)
PM ID: 19183483 PMC2637888
172: Plikus MV, Widelitz RB, Maxson R, Chuong CM
Analyses of regenerative wave patterns in adult hair follicle populations reveal macro-environmental regulation of stem cell activity.
Int J Dev Biol 53: 857-68 (2009)
PM ID: 19378257 PMC2759942 NIHMS131491
173: Campan M, Weisenberger DJ, Trinh BN, Laird PW
MethyLight.
Methods Mol Biol 507: 325-37 (2009)
PM ID: 18987824
174: Noh T, Gabet Y, Cogan JP, Shi Y, Tank A, Sasaki T, Criswell B, Dixon A, Lee CT, Tam J, Kohler T, Segev E, Kockeritz L, Woodgett JR, Müller R, Chai Y, Smith E, Bab I, Frenkel B
Lef1 haploinsufficient mice display a low turnover and low bone mass phenotype in a gender- and age-specific manner.
PLoS One 4: e5438 (2009)
PM ID: 19412553 PMC2673053
175: Zhou L, Yan C, Gieling RG, Kida Y, Garner WL, Li W, Han YP
Tumor necrosis factor-alpha induced expression of matrix metalloproteinase-9 through p21-activated kinase-1.
BMC Immunol 10: 15 (2009)
PM ID: 19298660 PMC2669056
176: Toleno DM, Renaud G, Wolfsberg TG, Islam M, Wildman DE, Siegmund KD, Hacia JG
Development and evaluation of new mask protocols for gene expression profiling in humans and chimpanzees.
BMC Bioinformatics 10: 77 (2009)
PM ID: 19265541 PMC2660304
177: Ni M, Zhou H, Wey S, Baumeister P, Lee AS
Regulation of PERK signaling and leukemic cell survival by a novel cytosolic isoform of the UPR regulator GRP78/BiP.
PLoS One 4: e6868 (2009)
PM ID: 19718440 PMC2729930
178: Joo J, Christensen L, Warner KL, States L, Kang HG, Vo K, Lawlor ER, May WA
GLI1 is a central mediator of EWS/FLI1 signaling in Ewing tumors.
PLoS One 4: e7608 (2009)
PM ID: 19859563 PMC2763206
179: Hinoue T, Weisenberger DJ, Pan F, Campan M, Kim M, Young J, Whitehall VL, Leggett BA, Laird PW
Analysis of the association between CIMP and BRAF in colorectal cancer by DNA methylation profiling.
PLoS One 4: e8357 (2009)
PM ID: 20027224 PMC2791229
180: Shtir C, Pique-Regi R, Siegmund K, Morrison J, Schumacher F, Marjoram P
Copy number variation in the Framingham Heart Study.
BMC Proc 3 Suppl 7: S133 (2009)
PM ID: 20018000 PMC2795907
181: Borok Z
Role for alpha3 integrin in EMT and pulmonary fibrosis.
J Clin Invest 119: 7-10 (2009)
PM ID: 19104143
182: Youssef RF, Mitra AP, Bartsch G, Jones PA, Skinner DG, Cote RJ
Molecular targets and targeted therapies in bladder cancer management.
World J Urol 27: 9-20 (2009)
PM ID: 19039591
183: Chen JL, Lin HH, Kim KJ, Lin AH, Ou JH, Ann DK
PKC delta signaling: a dual role in regulating hypoxic stress-induced autophagy and apoptosis.
Autophagy 5: 244-6 (2009)
PM ID: 19098423 PMC2743529 NIHMS123596
184: Saito Y, Friedman JM, Chihara Y, Egger G, Chuang JC, Liang G
Epigenetic therapy upregulates the tumor suppressor microRNA-126 and its host gene EGFL7 in human cancer cells.
Biochem Biophys Res Commun 379: 726-31 (2009)
PM ID: 19116145
185: Zhang ZY, Lan Y, Chai Y, Jiang R
Antagonistic actions of Msx1 and Osr2 pattern mammalian teeth into a single row.
Science 323: 1232-4 (2009)
PM ID: 19251632 PMC2650836 [Available on 02/27/10] NIHMS88200 [Available on 02/27/10]
186: Chuong CM, Widelitz RB
The river of stem cells.
Cell Stem Cell 4: 100-2 (2009)
PM ID: 19200797
187: Rountree CB, Ding W, He L, Stiles B
Expansion of CD133-expressing liver cancer stem cells in liver-specific phosphatase and tensin homolog deleted on chromosome 10-deleted mice.
Stem Cells 27: 290-9 (2009)
PM ID: 19008348
188: Wong AK, Mei L, Soares MA, Schönmeyr BH, Mehrara BJ
Radioprotection of osteoblasts by a fractionated dose regimen and amifostine.
Plast Reconstr Surg 123: 104S-13S (2009)
PM ID: 19182669
189: Asahina K, Tsai SY, Li P, Ishii M, Maxson RE, Sucov HM, Tsukamoto H
Mesenchymal origin of hepatic stellate cells, submesothelial cells, and perivascular mesenchymal cells during mouse liver development.
Hepatology 49: 998-1011 (2009)
PM ID: 19085956 PMC2673117 [Available on 03/01/10] NIHMS98872 [Available on 03/01/10]
190: Jariwala U, Cogan JP, Jia L, Frenkel B, Coetzee GA
Inhibition of AR-mediated transcription by binding of Oct1 to a motif enriched in AR-occupied regions.
Prostate 69: 392-400 (2009)
PM ID: 19058140 PMC2743387 NIHMS129716
191: Joshi AD, Corral R, Siegmund KD, Haile RW, Le Marchand L, Martínez ME, Ahnen DJ, Sandler RS, Lance P, Stern MC
Red meat and poultry intake, polymorphisms in the nucleotide excision repair and mismatch repair pathways and colorectal cancer risk.
Carcinogenesis 30: 472-9 (2009)
PM ID: 19029193 PMC2722151 [Available on 03/01/10]
192: Rich RL, Papalia GA, Flynn PJ, Furneisen J, Quinn JA, Klein JS, Katsamba PS, Waddell MB, Scott ML, Thompson JR, Berlier J, Corry S, Baltzinger M, Zeder-Lutz G, Schoenemann A, Clabbers A, Wieckowski S, Murphy MM, Page P, Ryan TE, Duffner J, Ganguly T, Corbin J, Gautam S, Anderluh G, Bavdek A, Reichmann D, Yadav SP, Hommema E, Pol E, Drake A, Klakamp S, Chapman T, Kernaghan D, Miller KD, Schuman J, Lindquist KC, Herlihy K, Murphy MB, Bohnsack R, Andrien B, Brandani P, Terwey D, Millican R, Darling RJ, Wang L, Carter Q, Dotzlaf J, Lopez-Sagaseta J, Campbell I, Torreri P, Hoos S, England P, Liu Y, Abdiche Y, Malashock D, Pinkerton A, Wong MM, Lafer E, Hinck C, Thompson K, Primo CD, Joyce A, Brooks J, Torta F, Bagge Hagel AB, Krarup J, Pass J, Ferreira MA, Shikov S, Mikolajczyk M, Abe Y, Barbato G, Giannetti AM, Krishnamoorthy G, Beusink B, Satpaev D, Tsang T, Fang E, Partridge J, Brohawn S, Horn J, Pritsch O, Obal G, Nilapwar S, Busby B, Gutierrez-Sanchez G, Gupta RD, Canepa S, Witte K, Nikolovska-Coleska Z, Cho YH, D'Agata R, Schlick K, Calvert R, Munoz EM, Hernaiz MJ, Bravman T, Dines M, Yang MH, Puskas A, Boni E, Li JZ, Wear M, Grinberg A, Baardsnes J, Dolezal O, Gainey M, Anderson H, Peng J, Lewis MA, Spies P, Trinh Q, Bibikov S, Raymond J, Yousef M, Chandrasekaran V, Feng Y, Emerick A, Mundodo S, Guimaraes R, McGirr K, Li YJ, Hughes H, Mantz H, Skrabana R, Witmer M, Ballard J, Martin L, Skladal P, Korza G, Laird-Offringa IA, Lee CS, Khadir A, Podlaski F, Neuner P, Rothacker J, Rafique A, Dankbar N, Kainz P, Gedig E, Vuyisich M, Boozer C, Ly N, Toews M, Uren A, Kalyuzhniy O, Lewis KD, Chomey E, Pak BJ, Myszka DG
A global benchmark study using affinity-based biosensors.
Anal Biochem 386: 194-216 (2009)
PM ID: 19133223
193: Ting MC, Wu NL, Roybal PG, Sun J, Liu L, Yen Y, Maxson RE
EphA4 as an effector of Twist1 in the guidance of osteogenic precursor cells during calvarial bone growth and in craniosynostosis.
Development 136: 855-64 (2009)
PM ID: 19201948 PMC2685950 [Available on 03/01/10] NIHMS131479 [Available on 03/01/10]
194: Friedman JM, Liang G, Liu CC, Wolff EM, Tsai YC, Ye W, Zhou XJ, Jones PA
The putative tumor suppressor microRNA-101 modulates the cancer epigenome by repressing the polycomb group protein EZH2.
Cancer Res 69: 2623-9 (2009)
PM ID: 19258506
195: Siegmund KD, Marjoram P, Woo YJ, Tavaré S, Shibata D
Inferring clonal expansion and cancer stem cell dynamics from DNA methylation patterns in colorectal cancers.
Proc Natl Acad Sci U S A 106: 4828-33 (2009)
PM ID: 19261858 PMC2651202
196: Jiang X, Castelao JE, Groshen S, Cortessis VK, Shibata D, Conti DV, Yuan JM, Pike MC, Gago-Dominguez M
Urinary tract infections and reduced risk of bladder cancer in Los Angeles.
Br J Cancer 100: 834-9 (2009)
PM ID: 19174821 PMC2653778 [Available on 03/10/10]
197: Woo YJ, Siegmund KD, Tavaré S, Shibata D
Older individuals appear to acquire mitotically older colorectal cancers.
J Pathol 217: 483-8 (2009)
PM ID: 19165870
198: Bapat B, Lindor NM, Baron JA, Siegmund KD, Li L, Zheng YT, Haile R, Gallinger S, Jass JR, Young JP, Cotterchio M, Jenkins MA, Grove J, Casey GR, Thibodeau SN, Bishop DT, Hopper JL, Ahnen DJ, Newcomb PA, Le Marchand L, Potter JD, Seminara D, Colon Cancer Family Registry
The association of tumor microsatellite instability phenotype with family history of colorectal cancer.
Cancer Epidemiol Biomarkers Prev 18: 967-75 (2009)
PM ID: 19258475 PMC2763617 [Available on 03/01/10] NIHMS139549 [Available on 03/01/10]
199: Shi SR, Chai Y, Slavkin HC
Emerging opportunities for the next generation of dental implants?
Dent Today 28: 98-9 (2009)
PM ID: 19323323
200: Patel LN, Wang JG, Kim KJ, Borok Z, Crandall ED, Shen WC
Conjugation with cationic cell-penetrating peptide increases pulmonary absorption of insulin.
Mol Pharm 6: 492-503 (2009)
PM ID: 19228019
201: Lyu J, Wesselschmidt RL, Lu W
Cdc37 regulates Ryk signaling by stabilizing the cleaved Ryk intracellular domain.
J Biol Chem 284: 12940-8 (2009)
PM ID: 19269974
202: Lee YH, Stallcup MR
Minireview: protein arginine methylation of nonhistone proteins in transcriptional regulation.
Mol Endocrinol 23: 425-33 (2009)
PM ID: 19164444 PMC2667706 [Available on 04/01/10]
203: Aparicio A, North B, Barske L, Wang X, Bollati V, Weisenberger D, Yoo C, Tannir N, Horne E, Groshen S, Jones P, Yang A, Issa JP
LINE-1 methylation in plasma DNA as a biomarker of activity of DNA methylation inhibitors in patients with solid tumors.
Epigenetics 4: 176-84 (2009)
PM ID: 19421002
204: Berman BP, Weisenberger DJ, Laird PW
Locking in on the human methylome.
Nat Biotechnol 27: 341-2 (2009)
PM ID: 19352369
205: Chung IH, Yamaza T, Zhao H, Choung PH, Shi SR, Chai Y
Stem cell property of postmigratory cranial neural crest cells and their utility in alveolar bone regeneration and tooth development.
Stem Cells 27: 866-77 (2009)
PM ID: 19350689
206: Stiles BL
Phosphatase and tensin homologue deleted on chromosome 10: extending its PTENtacles.
Int J Biochem Cell Biol 41: 757-61 (2009)
PM ID: 18950730
207: Sohn KJ, Jang H, Campan M, Weisenberger DJ, Dickhout J, Wang YC, Cho RC, Yates Z, Lucock M, Chiang EP, Austin RC, Choi SW, Laird PW, Kim YI
The methylenetetrahydrofolate reductase C677T mutation induces cell-specific changes in genomic DNA methylation and uracil misincorporation: a possible molecular basis for the site-specific cancer risk modification.
Int J Cancer 124: 1999-2005 (2009)
PM ID: 19123462 PMC2692263 [Available on 05/01/10] NIHMS99332 [Available on 05/01/10]
208: Kumar SR, Scehnet JS, Ley EJ, Singh J, Krasnoperov V, Liu R, Manchanda PK, Ladner RD, Hawes D, Weaver FA, Beart RW, Singh G, Nguyen C, Kahn M, Gill PS
Preferential induction of EphB4 over EphB2 and its implication in colorectal cancer progression.
Cancer Res 69: 3736-45 (2009)
PM ID: 19366806
209: Baumeister P, Dong D, Fu Y, Lee AS
Transcriptional induction of GRP78/BiP by histone deacetylase inhibitors and resistance to histone deacetylase inhibitor-induced apoptosis.
Mol Cancer Ther : (2009)
PM ID: 19417144
210: Berman BP, Frenkel B, Coetzee GA
Location, location, (ChIP-)location! Mapping chromatin landscapes one immunoprecipitation at a time.
J Cell Biochem 107: 1-5 (2009)
PM ID: 19308935 PMC2748114 [Available on 05/01/10] NIHMS136755 [Available on 05/01/10]
211: Woodley DT, Fan J, Cheng CF, Li YT, Chen M, Bu G, Li W
Participation of the lipoprotein receptor LRP1 in hypoxia-HSP90alpha autocrine signaling to promote keratinocyte migration.
J Cell Sci 122: 1495-8 (2009)
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212: Miranda TB, Cortez CC, Yoo CB, Liang G, Abe M, Kelly TK, Marquez VE, Jones PA
DZNep is a global histone methylation inhibitor that reactivates developmental genes not silenced by DNA methylation.
Mol Cancer Ther 8: 1579-88 (2009)
PM ID: 19509260
213: Demaio L, Tseng W, Balverde Z, Alvarez JR, Kim KJ, Kelley DG, Senior RM, Crandall ED, Borok Z
Characterization of mouse alveolar epithelial cell monolayers.
Am J Physiol Lung Cell Mol Physiol 296: L1051-8 (2009)
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214: Ou CY, Kim JH, Yang CK, Stallcup MR
Requirement of cell cycle and apoptosis regulator 1 for target gene activation by Wnt and beta-catenin and for anchorage-independent growth of human colon carcinoma cells.
J Biol Chem 284: 20629-37 (2009)
PM ID: 19520846 PMC2742827 [Available on 07/31/10]
215: Siegmund KD, Marjoram P, Tavaré S, Shibata D
Many colorectal cancers are "flat" clonal expansions.
Cell Cycle 8: 2187-93 (2009)
PM ID: 19556889
216: Li AY, Boo LM, Wang SY, Lin HH, Wang CC, Yen Y, Chen BP, Chen DJ, Ann DK
Suppression of nonhomologous end joining repair by overexpression of HMGA2.
Cancer Res 69: 5699-706 (2009)
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217: Kim HJ, Heo K, Kim JH, Kim KJ, Choi J, An W
Requirement of histone methyltransferase SMYD3 for estrogen receptor-mediated transcription.
J Biol Chem 284: 19867-77 (2009)
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218: Baniwal SK, Khalid O, Sir D, Buchanan G, Coetzee GA, Frenkel B
Repression of Runx2 by androgen receptor (AR) in osteoblasts and prostate cancer cells: AR binds Runx2 and abrogates its recruitment to DNA.
Mol Endocrinol 23: 1203-14 (2009)
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219: Pomerantz MM, Ahmadiyeh N, Jia L, Herman P, Verzi MP, Doddapaneni H, Beckwith CA, Chan JA, Hills A, Davis M, Yao KL, Kehoe SM, Lenz HJ, Haiman CA, Yan C, Henderson BE, Frenkel B, Barretina J, Bass A, Tabernero J, Baselga J, Regan MM, Manak JR, Shivdasani R, Coetzee GA, Freedman ML
The 8q24 cancer risk variant rs6983267 shows long-range interaction with MYC in colorectal cancer.
Nat Genet 41: 882-4 (2009)
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220: Guan S, Fan J, Han A, Chen M, Woodley DT, Li W
Non-compensating roles between Nckalpha and Nckbeta in PDGF-BB signaling to promote human dermal fibroblast migration.
J Invest Dermatol 129: 1909-20 (2009)
PM ID: 19242519
221: Choi SH, Worswick SD, Byun HM, Shear T, Soussa JC, Wolff EM, Douer D, Garcia-Manero G, Liang G, Yang AS
Changes in DNA methylation of tandem DNA repeats are different from interspersed repeats in cancer.
Int J Cancer 125: 723-9 (2009)
PM ID: 19437537
222: Friedman JM, Jones PA
MicroRNAs: critical mediators of differentiation, development and disease.
Swiss Med Wkly 139: 466-72 (2009)
PM ID: 19705306
223: Friedman JM, Jones PA, Liang G
The tumor suppressor microRNA-101 becomes an epigenetic player by targeting the polycomb group protein EZH2 in cancer.
Cell Cycle 8: 2313-4 (2009)
PM ID: 19625769
224: Jia L, Landan G, Pomerantz MM, Jaschek R, Herman P, Reich D, Yan C, Khalid O, Kantoff PW, Oh WK, Manak JR, Berman BP, Henderson BE, Frenkel B, Haiman CA, Freedman ML, Tanay A, Coetzee GA
Functional enhancers at the gene-poor 8q24 cancer-linked locus.
PLoS Genet 5: e1000597 (2009)
PM ID: 19680443 PMC2717370
225: Peters AA, Buchanan G, Ricciardelli C, Bianco-Miotto T, Centenera MM, Harris JM, Jindal S, Segara D, Jia L, Moore NL, Henshall SM, Birrell SN, Coetzee GA, Sutherland RL, Butler LM, Tilley WD
Androgen receptor inhibits estrogen receptor-alpha activity and is prognostic in breast cancer.
Cancer Res 69: 6131-40 (2009)
PM ID: 19638585
226: Li FP, Zeng B, Chai Y, Cai P, Fan C, Cheng T
The linker region of Smad2 mediates TGF-beta-dependent ERK2-induced collagen synthesis.
Biochem Biophys Res Commun 386: 289-93 (2009)
PM ID: 19465000
227: Zhong S, Johnson DL
The JNKs differentially regulate RNA polymerase III transcription by coordinately modulating the expression of all TFIIIB subunits.
Proc Natl Acad Sci U S A 106: 12682-7 (2009)
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228: Jiang X, Gwye Y, McKeown SJ, Bronner-Fraser M, Lutzko C, Lawlor ER
Isolation and characterization of neural crest stem cells derived from in vitro-differentiated human embryonic stem cells.
Stem Cells Dev 18: 1059-70 (2009)
PM ID: 19099373
229: Wang M, Wey S, Zhang Y, Ye R, Lee AS
Role of the unfolded protein response regulator GRP78/BiP in development, cancer, and neurological disorders.
Antioxid Redox Signal 11: 2307-16 (2009)
PM ID: 19309259
230: Bouazoune K, Miranda TB, Jones PA, Kingston RE
Analysis of individual remodeled nucleosomes reveals decreased histone-DNA contacts created by hSWI/SNF.
Nucleic Acids Res 37: 5279-94 (2009)
PM ID: 19567737 PMC2760786
231: Spektor TM, Rice JC
Identification and characterization of posttranslational modification-specific binding proteins in vivo by mammalian tethered catalysis.
Proc Natl Acad Sci U S A 106: 14808-13 (2009)
PM ID: 19706462
232: Dieli-Conwright CM, Spektor TM, Rice JC, Schroeder ET
Hormone therapy attenuates exercise-induced skeletal muscle damage in postmenopausal women.
J Appl Physiol 107: 853-8 (2009)
PM ID: 19574506
233: Willis BC, Borok Z
Epithelial-mesenchymal transition: potential role in obliterative bronchiolitis?
Thorax 64: 742-3 (2009)
PM ID: 19717708
234: Lee HR, Kim MH, Lee JS, Liang C, Jung JU
Viral interferon regulatory factors.
J Interferon Cytokine Res 29: 621-7 (2009)
PM ID: 19715458
235: Gundimeda U, Schiffman JE, Gottlieb SN, Roth BI, Gopalakrishna R
Negation of the cancer-preventive actions of selenium by over-expression of protein kinase Cepsilon and selenoprotein thioredoxin reductase.
Carcinogenesis 30: 1553-61 (2009)
PM ID: 19578042
236: Jeong KW, Lee YH, Stallcup MR
Recruitment of the SWI/SNF chromatin remodeling complex to steroid hormone-regulated promoters by nuclear receptor coactivator flightless-I.
J Biol Chem 284: 29298-309 (2009)
PM ID: 19720835
237: Jeong S, Liang G, Sharma S, Lin JC, Choi SH, Han H, Yoo CB, Egger G, Yang AS, Jones PA
Selective anchoring of DNA methyltransferases 3A and 3B to nucleosomes containing methylated DNA.
Mol Cell Biol 29: 5366-76 (2009)
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238: Poynter JN, Haile RW, Siegmund KD, Campbell PT, Figueiredo JC, Limburg P, Young J, Le Marchand L, Potter JD, Cotterchio M, Casey G, Hopper JL, Jenkins MA, Thibodeau SN, Newcomb PA, Baron JA, Colon Cancer Family Registry
Associations between smoking, alcohol consumption, and colorectal cancer, overall and by tumor microsatellite instability status.
Cancer Epidemiol Biomarkers Prev 18: 2745-50 (2009)
PM ID: 19755657 PMC2759847 NIHMS140217
239: Huang X, Bringas P, Slavkin HC, Chai Y
Fate of HERS during tooth root development.
Dev Biol 334: 22-30 (2009)
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240: Lin CM, Jiang TX, Baker RE, Maini PK, Widelitz RB, Chuong CM
Spots and stripes: pleomorphic patterning of stem cells via p-ERK-dependent cell chemotaxis shown by feather morphogenesis and mathematical simulation.
Dev Biol 334: 369-82 (2009)
PM ID: 19647731
241: Choi J, Heo K, An W
Cooperative action of TIP48 and TIP49 in H2A.Z exchange catalyzed by acetylation of nucleosomal H2A.
Nucleic Acids Res 37: 5993-6007 (2009)
PM ID: 19696079 PMC2764430
242: Tiozzo C, De Langhe S, Yu MC, Londhe VA, Carraro G, Li M, Li C, Xing Y, Anderson SA, Borok Z, Bellusci S, Minoo P
Deletion of Pten expands lung epithelial progenitor pools and confers resistance to airway injury.
Am J Respir Crit Care Med 180: 701-12 (2009)
PM ID: 19574443
243: E X, Hwang S, Oh S, Lee JS, Jeong JH, Gwack Y, Kowalik TF, Sun R, Jung JU, Liang C
Viral Bcl-2-mediated evasion of autophagy aids chronic infection of gammaherpesvirus 68.
PLoS Pathog 5: e1000609 (2009)
PM ID: 19816569 PMC2752191
244: Jones PA, Liang G
Rethinking how DNA methylation patterns are maintained.
Nat Rev Genet 10: 805-11 (2009)
PM ID: 19789556 PMC2848124 [Available on 11/01/10] NIHMS185221 [Available on 11/01/10]
245: Gaudet MM, Campan M, Figueroa JD, Yang XR, Lissowska J, Peplonska B, Brinton LA, Rimm DL, Laird PW, Garcia-Closas M, Sherman ME
DNA hypermethylation of ESR1 and PGR in breast cancer: pathologic and epidemiologic associations.
Cancer Epidemiol Biomarkers Prev 18: 3036-43 (2009)
PM ID: 19861523 PMC2783691 [Available on 11/01/10] NIHMS149883 [Available on 11/01/10]
246: Dieli-Conwright CM, Spektor TM, Rice JC, Sattler FR, Schroeder ET
Influence of hormone replacement therapy on eccentric exercise induced myogenic gene expression in postmenopausal women.
J Appl Physiol 107: 1381-8 (2009)
PM ID: 19696363 PMC2777804 [Available on 11/01/10]
247: Dieli-Conwright CM, Spektor TM, Rice JC, Todd Schroeder E
Oestradiol and SERM treatments influence oestrogen receptor coregulator gene expression in human skeletal muscle cells.
Acta Physiol (Oxf) 197: 187-96 (2009)
PM ID: 19432593
248: Felton VM, Borok Z, Willis BC
N-acetylcysteine inhibits alveolar epithelial-mesenchymal transition.
Am J Physiol Lung Cell Mol Physiol 297: L805-12 (2009)
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249: Lee JS, Li Q, Lee JY, Lee SH, Jeong JH, Lee HR, Chang H, Zhou FC, Gao SJ, Liang C, Jung JU
FLIP-mediated autophagy regulation in cell death control.
Nat Cell Biol 11: 1355-62 (2009)
PM ID: 19838173 PMC2802862 [Available on 11/01/10] NIHMS165792 [Available on 11/01/10]
250: Xu TX, Sotnikova TD, Liang C, Zhang J, Jung JU, Spealman RD, Gainetdinov RR, Yao WD
Hyperdopaminergic tone erodes prefrontal long-term potential via a D2 receptor-operated protein phosphatase gate.
J Neurosci 29: 14086-99 (2009)
PM ID: 19906957 PMC2818669 [Available on 05/11/10] NIHMS163955 [Available on 05/11/10]
251: Stiles BL
PI-3-K and AKT: Onto the mitochondria.
Adv Drug Deliv Rev 61: 1276-82 (2009)
PM ID: 19720099
252: Hu K, Lee C, Qiu D, Fotovati A, Davies A, Abu-Ali S, Wai D, Lawlor ER, Triche TJ, Pallen CJ, Dunn SE
Small interfering RNA library screen of human kinases and phosphatases identifies polo-like kinase 1 as a promising new target for the treatment of pediatric rhabdomyosarcomas.
Mol Cancer Ther 8: 3024-35 (2009)
PM ID: 19887553 PMC2783569 [Available on 11/03/10] NIHMS150149 [Available on 11/03/10]
253: Lee AS
The Par-4-GRP78 TRAIL, more twists and turns.
Cancer Biol Ther 8: 2103-5 (2009)
PM ID: 19823030
254: Byun HM, Siegmund KD, Pan F, Weisenberger DJ, Kanel G, Laird PW, Yang AS
Epigenetic profiling of somatic tissues from human autopsy specimens identifies tissue- and individual-specific DNA methylation patterns.
Hum Mol Genet 18: 4808-17 (2009)
PM ID: 19776032
255: Kazarian M, Calbo J, Proost N, Carpenter CL, Berns A, Laird-Offringa IA
Immune response in lung cancer mouse model mimics human anti-Hu reactivity.
J Neuroimmunol 217: 38-45 (2009)
PM ID: 19765830 PMC2788043 [Available on 12/10/10] NIHMS144833 [Available on 12/10/10]
256: Borok Z, Crandall ED
More life for a "terminal" cell.
Am J Physiol Lung Cell Mol Physiol 297: L1042-4 (2009)
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257: Wei Z, Yang Y, Zhang P, Andrianakos R, Hasegawa K, Lyu J, Chen X, Bai G, Liu C, Pera M, Lu W
Klf4 interacts directly with Oct4 and Sox2 to promote reprogramming.
Stem Cells 27: 2969-78 (2009)
PM ID: 19816951
258: Ricca TI, Liang G, Suenaga AP, Han SW, Jones PA, Jasiulionis MG
Tissue inhibitor of metalloproteinase 1 expression associated with gene demethylation confers anoikis resistance in early phases of melanocyte malignant transformation.
Transl Oncol 2: 329-40 (2009)
PM ID: 19956395 PMC2781071
259: Calabrese P, Shibata D
A simple algebraic cancer equation: calculating how cancers may arise with normal mutation rates.
BMC Cancer 10: 3 (2010)
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260: Houshdaran S, Hawley S, Palmer C, Campan M, Olsen MN, Ventura AP, Knudsen BS, Drescher CW, Urban ND, Brown PO, Laird PW
DNA methylation profiles of ovarian epithelial carcinoma tumors and cell lines.
PLoS One 5: e9359 (2010)
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261: Mao C, Wang M, Luo B, Wey S, Dong D, Wesselschmidt R, Rawlings S, Lee AS
Targeted mutation of the mouse Grp94 gene disrupts development and perturbs endoplasmic reticulum stress signaling.
PLoS One 5: e10852 (2010)
PM ID: 20520781 PMC2877114
262: Wolff EM, Byun HM, Han HF, Sharma S, Nichols PW, Siegmund KD, Yang AS, Jones PA, Liang G
Hypomethylation of a LINE-1 promoter activates an alternate transcript of the MET oncogene in bladders with cancer.
PLoS Genet 6: e1000917 (2010)
PM ID: 20421991 PMC2858672
263: Kim M, Long TI, Arakawa K, Wang R, Yu MC, Laird PW
DNA methylation as a biomarker for cardiovascular disease risk.
PLoS One 5: e9692 (2010)
PM ID: 20300621 PMC2837739
264: Jiang X, Gwye Y, Russell D, Cao C, Douglas D, Hung L, Kovar H, Triche TJ, Lawlor ER
CD133 expression in chemo-resistant Ewing sarcoma cells.
BMC Cancer 10: 116 (2010)
PM ID: 20346143 PMC2851692
265: Qiu X, Hother C, Ralfkiær UM, Søgaard A, Lu Q, Workman CT, Liang G, Jones PA, Grønbaek K
Equitoxic doses of 5-azacytidine and 5-aza-2'deoxycytidine induce diverse immediate and overlapping heritable changes in the transcriptome.
PLoS One 5: (2010)
PM ID: 20927380 PMC2947512
266: Hong YJ, Marjoram P, Shibata D, Siegmund KD
Using DNA methylation patterns to infer tumor ancestry.
PLoS One 5: e12002 (2010)
PM ID: 20711251 PMC2918495
267: Baniwal SK, Khalid O, Gabet Y, Shah RR, Purcell DJ, Mav D, Kohn-Gabet AE, Shi Y, Coetzee GA, Frenkel B
Runx2 transcriptome of prostate cancer cells: insights into invasiveness and bone metastasis.
Mol Cancer 9: 258 (2010)
PM ID: 20863401 PMC2955618
268: Mrkonjic M, Roslin NM, Greenwood CM, Raptis S, Pollett A, Laird PW, Pethe VV, Chiang T, Daftary D, Dicks E, Thibodeau SN, Gallinger S, Parfrey PS, Younghusband HB, Potter JD, Hudson TJ, McLaughlin JR, Green RC, Zanke BW, Newcomb PA, Paterson AD, Bapat B
Specific variants in the MLH1 gene region may drive DNA methylation, loss of protein expression, and MSI-H colorectal cancer.
PLoS One 5: e13314 (2010)
PM ID: 20967208 PMC2954166
269: Toth Z, Maglinte DT, Lee SH, Lee HR, Wong LY, Brulois KF, Lee S, Buckley JD, Laird PW, Marquez VE, Jung JU
Epigenetic analysis of KSHV latent and lytic genomes.
PLoS Pathog 6: e1001013 (2010)
PM ID: 20661424 PMC2908616
270: Watkins PA, Moser AB, Toomer CB, Steinberg SJ, Moser HW, Karaman MW, Ramaswamy K, Siegmund KD, Lee DR, Ely JJ, Ryder OA, Hacia JG
Identification of differences in human and great ape phytanic acid metabolism that could influence gene expression profiles and physiological functions.
BMC Physiol 10: 19 (2010)
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271: Ye R, Jung DY, Jun JY, Li J, Luo S, Ko HJ, Kim JK, Lee AS
Grp78 heterozygosity promotes adaptive unfolded protein response and attenuates diet-induced obesity and insulin resistance.
Diabetes 59: 6-16 (2010)
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272: Sharma S, Kelly TK, Jones PA
Epigenetics in cancer.
Carcinogenesis 31: 27-36 (2010)
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273: Zhong JF, Weiner L, Jin Y, Lu W, Taylor CR
A real-time pluripotency reporter for human stem cells.
Stem Cells Dev 19: 47-52 (2010)
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274: Miranda TB, Kelly TK, Bouazoune K, Jones PA
Methylation-sensitive single-molecule analysis of chromatin structure.
Curr Protoc Mol Biol Chapter 21: Unit 21.17.1-16 (2010)
PM ID: 20069538
275: Wolkenhauer O, Auffray C, Baltrusch S, Blüthgen N, Byrne H, Cascante M, Ciliberto A, Dale T, Drasdo D, Fell D, Ferrell JE, Gallahan D, Gatenby R, Günther U, Harms BD, Herzel H, Junghanss C, Kunz M, van Leeuwen I, Lenormand P, Levi F, Linnebacher M, Lowengrub J, Maini PK, Malik A, Rateitschak K, Sansom O, Schäfer R, Schürrle K, Sers C, Schnell S, Shibata D, Tyson J, Vera J, White M, Zhivotovsky B, Jaster R
Systems biologists seek fuller integration of systems biology approaches in new cancer research programs.
Cancer Res 70: 12-3 (2010)
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276: Coetzee GA, Jia L, Frenkel B, Henderson BE, Tanay A, Haiman CA, Freedman ML
A systematic approach to understand the functional consequences of non-protein coding risk regions.
Cell Cycle 9: 256-9 (2010)
PM ID: 20023379
277: Hong H, Yen HY, Brockmeyer A, Liu Y, Chodankar R, Pike MC, Stanczyk FZ, Maxson R, Dubeau L
Changes in the mouse estrus cycle in response to BRCA1 inactivation suggest a potential link between risk factors for familial and sporadic ovarian cancer.
Cancer Res 70: 221-8 (2010)
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278: Oh S, E X, Hwang S, Liang C
Autophagy evasion in herpesviral latency.
Autophagy 6: 151-2 (2010)
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279: Laird PW
Principles and challenges of genome-wide DNA methylation analysis.
Nat Rev Genet 11: 191-203 (2010)
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280: Iwata J, Hosokawa R, Sanchez-Lara PA, Urata M, Slavkin H, Chai Y
Transforming growth factor-beta regulates basal transcriptional regulatory machinery to control cell proliferation and differentiation in cranial neural crest-derived osteoprogenitor cells.
J Biol Chem 285: 4975-82 (2010)
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281: Wang M, Ye R, Barron E, Baumeister P, Mao C, Luo S, Fu Y, Luo B, Dubeau L, Hinton DR, Lee AS
Essential role of the unfolded protein response regulator GRP78/BiP in protection from neuronal apoptosis.
Cell Death Differ 17: 488-98 (2010)
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282: Wang XM, Greiner TC, Bibikova M, Pike BL, Siegmund KD, Sinha UK, Müschen M, Jaeger EB, Weisenburger DD, Chan WC, Shibata D, Fan JB, Hacia JG
Identification and functional relevance of de novo DNA methylation in cancerous B-cell populations.
J Cell Biochem 109: 818-27 (2010)
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283: Sir D, Tian Y, Chen WL, Ann DK, Yen TS, Ou JH
The early autophagic pathway is activated by hepatitis B virus and required for viral DNA replication.
Proc Natl Acad Sci U S A 107: 4383-8 (2010)
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284: Zhang P, Andrianakos R, Yang Y, Liu C, Lu W
Kruppel-like factor 4 (Klf4) prevents embryonic stem (ES) cell differentiation by regulating Nanog gene expression.
J Biol Chem 285: 9180-9 (2010)
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Signaling via Alk5 controls the ontogeny of lung Clara cells.
Development 137: 825-33 (2010)
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Autophagy genes as tumor suppressors.
Curr Opin Cell Biol 22: 226-33 (2010)
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287: Lu L, Wang J, Zhang F, Chai Y, Brand D, Wang X, Horwitz DA, Shi W, Zheng SG
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288: van Doorninck JA, Ji L, Schaub B, Shimada H, Wing MR, Krailo MD, Lessnick SL, Marina N, Triche TJ, Sposto R, Womer RB, Lawlor ER
Current treatment protocols have eliminated the prognostic advantage of type 1 fusions in Ewing sarcoma: a report from the Children's Oncology Group.
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A histone methylation code for SV40 minichromosomes.
Cell Cycle 9: (2010)
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292: Vázquez-Chantada M, Fernández-Ramos D, Embade N, Martínez-Lopez N, Varela-Rey M, Woodhoo A, Luka Z, Wagner C, Anglim PP, Finnell RH, Caballería J, Laird-Offringa IA, Gorospe M, Lu SC, Mato JM, Martínez-Chantar ML
HuR/methyl-HuR and AUF1 regulate the MAT expressed during liver proliferation, differentiation, and carcinogenesis.
Gastroenterology 138: 1943-53 (2010)
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293: Huang X, Xu X, Bringas P, Hung YP, Chai Y
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J Bone Miner Res 25: 1167-78 (2010)
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294: Zhang Y, Liu R, Ni M, Gill P, Lee AS
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Mol Cancer Ther 9: 1443-50 (2010)
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296: Sir D, Ann DK, Ou JH
Autophagy by hepatitis B virus and for hepatitis B virus.
Autophagy 6: (2010)
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8q24 prostate, breast, and colon cancer risk loci show tissue-specific long-range interaction with MYC.
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Chembiochem 11: 1219-23 (2010)
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The endothelial cell receptor GRP78 is required for mucormycosis pathogenesis in diabetic mice.
J Clin Invest 120: 1914-24 (2010)
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303: Berman BP, Frenkel B, Coetzee GA, Jia L
Androgen receptor responsive enhancers are flanked by consistently-positioned H3-acetylated nucleosomes.
Cell Cycle 9: 2249-50 (2010)
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304: Ding W, You H, Dang H, Leblanc F, Galicia V, Lu SC, Stiles B, Rountree CB
Epithelial-to-mesenchymal transition of murine liver tumor cells promotes invasion.
Hepatology : (2010)
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305: Roybal PG, Wu NL, Sun J, Ting MC, Schafer CA, Maxson RE
Inactivation of Msx1 and Msx2 in neural crest reveals an unexpected role in suppressing heterotopic bone formation in the head.
Dev Biol 343: 28-39 (2010)
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306: Limsui D, Vierkant RA, Tillmans LS, Wang AH, Weisenberger DJ, Laird PW, Lynch CF, Anderson KE, French AJ, Haile RW, Harnack LJ, Potter JD, Slager SL, Smyrk TC, Thibodeau SN, Cerhan JR, Limburg PJ
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Microcell-mediated chromosome transfer identifies EPB41L3 as a functional suppressor of epithelial ovarian cancers.
Neoplasia 12: 579-89 (2010)
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308: Flodby P, Borok Z, Banfalvi A, Zhou B, Gao D, Minoo P, Ann DK, Morrisey EE, Crandall ED
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DNA Repair (Amst) 9: 858; discussion 859-60 (2010)
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312: Diamandis EP, Sidransky D, Laird PW, Cairns P, Bapat B
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313: Henderson WR, Chi EY, Ye X, Nguyen C, Tien YT, Zhou B, Borok Z, Knight DA, Kahn M
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314: Kelly TK, Miranda TB, Liang G, Berman BP, Lin JC, Tanay A, Jones PA
H2A.Z maintenance during mitosis reveals nucleosome shifting on mitotically silenced genes.
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Nat Biotechnol 28: 1069-1078 (2010)
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318: Wolff EM, Chihara Y, Pan F, Weisenberger DJ, Siegmund KD, Sugano K, Kawashima K, Laird PW, Jones PA, Liang G
Unique DNA methylation patterns distinguish noninvasive and invasive urothelial cancers and establish an epigenetic field defect in premalignant tissue.
Cancer Res 70: 8169-78 (2010)
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321: Yen HY, Ting MC, Maxson RE
Jagged1 functions downstream of Twist1 in the specification of the coronal suture and the formation of a boundary between osteogenic and non-osteogenic cells.
Dev Biol 347: 258-70 (2010)
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322: Yang X, Lay F, Han H, Jones PA
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324: Lau HD, Yaegashi J, Zaro BW, Pratt MR
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Angew Chem Int Ed Engl 49: 8458-61 (2010)
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Green tea polyphenols potentiate the action of nerve growth factor to induce neuritogenesis: possible role of reactive oxygen species.
J Neurosci Res 88: 3644-55 (2010)
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Polymorphisms in base excision repair genes as colorectal cancer risk factors and modifiers of the effect of diets high in red meat.
Cancer Epidemiol Biomarkers Prev 19: 3167-73 (2010)
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Liver-specific deletion of prohibitin 1 results in spontaneous liver injury, fibrosis, and hepatocellular carcinoma in mice.
Hepatology 52: 2096-108 (2010)
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330: Galicia VA, He L, Dang H, Kanel G, Vendryes C, French BA, Zeng N, Bayan JA, Ding W, Wang KS, French S, Birnbaum MJ, Rountree CB, Stiles BL
Expansion of hepatic tumor progenitor cells in Pten-null mice requires liver injury and is reversed by loss of AKT2.
Gastroenterology 139: 2170-82 (2010)
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TSLP polymorphisms are associated with asthma in a sex-specific fashion.
Allergy 65: 1566-75 (2010)
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332: Chen WT, Lee AS
Measurement and modification of the expression level of the chaperone protein and signaling regulator GRP78/BiP in mammalian cells.
Methods Enzymol 490: 217-33 (2011)
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333: Sharma S, De Carvalho DD, Jeong S, Jones PA, Liang G
Nucleosomes containing methylated DNA stabilize DNA methyltransferases 3A/3B and ensure faithful epigenetic inheritance.
PLoS Genet 7: e1001286 (2011)
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DNA methylation and cancer.
Prog Drug Res 67: 1-23 (2011)
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335: Jeong JH, Bhatia A, Toth Z, Oh S, Inn KS, Liao CP, Roy-Burman P, Melamed J, Coetzee GA, Jung JU
TPL2/COT/MAP3K8 (TPL2) activation promotes androgen depletion-independent (ADI) prostate cancer growth.
PLoS One 6: e16205 (2011)
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336: Kazarian M, Laird-Offringa IA
Small-cell lung cancer-associated autoantibodies: potential applications to cancer diagnosis, early detection, and therapy.
Mol Cancer 10: 33 (2011)
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337: Moser AB, Steinberg SJ, Watkins PA, Moser HW, Ramaswamy K, Siegmund KD, Lee DR, Ely JJ, Ryder OA, Hacia JG
Human and great ape red blood cells differ in plasmalogen levels and composition.
Lipids Health Dis 10: 101 (2011)
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338: Siegmund KD, Marjoram P, Tavaré S, Shibata D
High DNA methylation pattern intratumoral diversity implies weak selection in many human colorectal cancers.
PLoS One 6: e21657 (2011)
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339: Selamat SA, Galler JS, Joshi AD, Fyfe MN, Campan M, Siegmund KD, Kerr KM, Laird-Offringa IA
DNA methylation changes in atypical adenomatous hyperplasia, adenocarcinoma in situ, and lung adenocarcinoma.
PLoS One 6: e21443 (2011)
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340: Luo B, Lam BS, Lee SH, Wey S, Zhou H, Wang M, Chen SY, Adams GB, Lee AS
The endoplasmic reticulum chaperone protein GRP94 is required for maintaining hematopoietic stem cell interactions with the adult bone marrow niche.
PLoS One 6: e20364 (2011)
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Transcription factor effector domains.
Subcell Biochem 52: 261-77 (2011)
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342: Wang X, Kang GH, Campan M, Weisenberger DJ, Long TI, Cozen W, Bernstein L, Wu AH, Siegmund KD, Shibata D, Laird PW
Epigenetic subgroups of esophageal and gastric adenocarcinoma with differential GATA5 DNA methylation associated with clinical and lifestyle factors.
PLoS One 6: e25985 (2011)
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343: Rakovski C, Weisenberger DJ, Marjoram P, Laird PW, Siegmund KD
Modeling measurement error in tumor characterization studies.
BMC Bioinformatics 12: 284 (2011)
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344: Fazlollahi F, Sipos A, Kim YH, Hamm-Alvarez SF, Borok Z, Kim KJ, Crandall ED
Translocation of PEGylated quantum dots across rat alveolar epithelial cell monolayers.
Int J Nanomedicine 6: 2849-57 (2011)
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345: Campan M, Moffitt M, Houshdaran S, Shen H, Widschwendter M, Daxenbichler G, Long T, Marth C, Laird-Offringa IA, Press MF, Dubeau L, Siegmund KD, Wu AH, Groshen S, Chandavarkar U, Roman LD, Berchuck A, Pearce CL, Laird PW
Genome-scale screen for DNA methylation-based detection markers for ovarian cancer.
PLoS One 6: e28141 (2011)
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346: Chimge NO, Baniwal SK, Little GH, Chen YB, Kahn M, Tripathy D, Borok Z, Frenkel B
Regulation of breast cancer metastasis by Runx2 and estrogen signaling: the role of SNAI2.
Breast Cancer Res 13: R127 (2011)
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347: Pirooz SD, Lee JH, Zhao Z, Ni D, Oh S, Liang C
Measurement of γHV68 Infection in Mice.
J Vis Exp : (2011)
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348: Jung CJ, Iyengar S, Blahnik KR, Ajuha TP, Jiang JX, Farnham PJ, Zern M
Epigenetic modulation of miR-122 facilitates human embryonic stem cell self-renewal and hepatocellular carcinoma proliferation.
PLoS One 6: e27740 (2011)
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349: Cooper A, van Doorninck J, Ji L, Russell D, Ladanyi M, Shimada H, Krailo M, Womer RB, Hsu JH, Thomas D, Triche TJ, Sposto R, Lawlor ER
Ewing tumors that do not overexpress BMI-1 are a distinct molecular subclass with variant biology: a report from the Children's Oncology Group.
Clin Cancer Res 17: 56-66 (2011)
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350: Zhang W, Winder T, Ning Y, Pohl A, Yang D, Kahn M, Lurje G, Labonte MJ, Wilson PM, Gordon MA, Hu-Lieskovan S, Mauro DJ, Langer C, Rowinsky EK, Lenz HJ
A let-7 microRNA-binding site polymorphism in 3'-untranslated region of KRAS gene predicts response in wild-type KRAS patients with metastatic colorectal cancer treated with cetuximab monotherapy.
Ann Oncol 22: 104-9 (2011)
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351: Zhong S, Machida K, Tsukamoto H, Johnson DL
Alcohol induces RNA polymerase III-dependent transcription through c-Jun by co-regulating TATA-binding protein (TBP) and Brf1 expression.
J Biol Chem 286: 2393-401 (2011)
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TbetaRI/Alk5-independent TbetaRII signaling to ERK1/2 in human skin cells according to distinct levels of TbetaRII expression.
J Cell Sci 124: 19-24 (2011)
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The PREMM(1,2,6) model predicts risk of MLH1, MSH2, and MSH6 germline mutations based on cancer history.
Gastroenterology 140: 73-81 (2011)
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354: Rumilla K, Schowalter KV, Lindor NM, Thomas BC, Mensink KA, Gallinger S, Holter S, Newcomb PA, Potter JD, Jenkins MA, Hopper JL, Long TI, Weisenberger DJ, Haile RW, Casey G, Laird PW, Le Marchand L, Thibodeau SN
Frequency of deletions of EPCAM (TACSTD1) in MSH2-associated lynch syndrome cases.
J Mol Diagn 13: 93-9 (2011)
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Regulated recruitment of tumor suppressor BRCA1 to the p21 gene by coactivator methylation.
Genes Dev 25: 176-88 (2011)
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356: Li M, Krishnaveni MS, Li C, Zhou B, Xing Y, Banfalvi A, Li A, Lombardi V, Akbari O, Borok Z, Minoo P
Epithelium-specific deletion of TGF-β receptor type II protects mice from bleomycin-induced pulmonary fibrosis.
J Clin Invest 121: 277-87 (2011)
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357: Choi SH, Heo K, Byun HM, An W, Lu W, Yang AS
Identification of preferential target sites for human DNA methyltransferases.
Nucleic Acids Res 39: 104-18 (2011)
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358: Iqbal S, Tsao-Wei DD, Quinn DI, Gitlitz BJ, Groshen S, Aparicio A, Lenz HJ, El-Khoueiry A, Pinski J, Garcia AA
Phase I clinical trial of pegylated liposomal Doxorubicin and docetaxel in patients with advanced solid tumors.
Am J Clin Oncol 34: 27-31 (2011)
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359: Lee E, Nichols P, Groshen S, Spicer D, Lee AS
GRP78 as potential predictor for breast cancer response to adjuvant taxane therapy.
Int J Cancer 128: 726-31 (2011)
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360: Shibata D
Mutation and epigenetic molecular clocks in cancer.
Carcinogenesis 32: 123-8 (2011)
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361: Kelly TK, Jones PA
Role of nucleosomes in mitotic bookmarking.
Cell Cycle 10: 370-1 (2011)
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362: Oh S, Pirooz SD, Ni D, Zhao Z, Liang C
Anti-autophagic Bcl-2: Not just an innocent bystander.
Autophagy 7: 231-2 (2011)
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363: Ouyang YB, Xu LJ, Emery JF, Lee AS, Giffard RG
Overexpressing GRP78 influences Ca2+ handling and function of mitochondria in astrocytes after ischemia-like stress.
Mitochondrion 11: 279-86 (2011)
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364: Oh S, Xiaofei E, Ni D, Pirooz SD, Lee JY, Lee D, Zhao Z, Lee S, Lee H, Ku B, Kowalik T, Martin SE, Oh BH, Jung JU, Liang C
Downregulation of autophagy by Bcl-2 promotes MCF7 breast cancer cell growth independent of its inhibition of apoptosis.
Cell Death Differ 18: 452-64 (2011)
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Beyond the endoplasmic reticulum: atypical GRP78 in cell viability, signalling and therapeutic targeting.
Biochem J 434: 181-8 (2011)
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The critical role of GRP78 in physiologic and pathologic stress.
Curr Opin Cell Biol 23: 150-6 (2011)
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Evidence that inhibition of BAX activation by BCL-2 involves its tight and preferential interaction with the BH3 domain of BAX.
Cell Res 21: 627-41 (2011)
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368: Protiva P, Mason JB, Liu Z, Hopkins ME, Nelson C, Marshall JR, Lambrecht RW, Pendyala S, Kopelovich L, Kim M, Kleinstein SH, Laird PW, Lipkin M, Holt PR
Altered folate availability modifies the molecular environment of the human colorectum: implications for colorectal carcinogenesis.
Cancer Prev Res (Phila) 4: 530-43 (2011)
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369: Hughes MW, Wu P, Jiang TX, Lin SJ, Dong CY, Li A, Hsieh FJ, Widelitz RB, Chuong CM
In search of the Golden Fleece: unraveling principles of morphogenesis by studying the integrative biology of skin appendages.
Integr Biol (Camb) 3: 388-407 (2011)
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370: Molognoni F, Cruz AT, Meliso FM, Morais AS, Souza CF, Xander P, Bischof JM, Costa FF, Soares MB, Liang G, Jones PA, Jasiulionis MG
Epigenetic reprogramming as a key contributor to melanocyte malignant transformation.
Epigenetics 6: 450-64 (2011)
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371: Dong D, Stapleton C, Luo B, Xiong S, Ye W, Zhang Y, Jhaveri N, Zhu G, Ye R, Liu Z, Bruhn KW, Craft N, Groshen S, Hofman FM, Lee AS
A critical role for GRP78/BiP in the tumor microenvironment for neovascularization during tumor growth and metastasis.
Cancer Res 71: 2848-57 (2011)
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Genome-wide analysis of transcription factor E2F1 mutant proteins reveals that N- and C-terminal protein interaction domains do not participate in targeting E2F1 to the human genome.
J Biol Chem 286: 11985-96 (2011)
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Alk5-mediated transforming growth factor β signaling acts upstream of fibroblast growth factor 10 to regulate the proliferation and maintenance of dental epithelial stem cells.
Mol Cell Biol 31: 2079-89 (2011)
PM ID: 21402782 PMC3133354 [Available on 11/01/11]
374: Ou CY, LaBonte MJ, Manegold PC, So AY, Ianculescu I, Gerke DS, Yamamoto KR, Ladner RD, Kahn M, Kim JH, Stallcup MR
A coactivator role of CARM1 in the dysregulation of β-catenin activity in colorectal cancer cell growth and gene expression.
Mol Cancer Res 9: 660-70 (2011)
PM ID: 21478268 PMC3096696 [Available on 05/01/12] NIHMS284281 [Available on 05/01/12]
375: Lee YH, Stallcup MR
Roles of protein arginine methylation in DNA damage signaling pathways: Is CARM1 a life-or-death decision point?
Cell Cycle 10: 1343-4 (2011)
PM ID: 21445011 PMC3117038 [Available on 05/01/12]
376: Hung Y, Huang X, Chai Y
Molecular regulatory mechanism of root development.
J Calif Dent Assoc 39: 321-4 (2011)
PM ID: 21721476
377: Li J, Huang X, Xu X, Mayo J, Bringas P, Jiang R, Wang S, Chai Y
SMAD4-mediated WNT signaling controls the fate of cranial neural crest cells during tooth morphogenesis.
Development 138: 1977-89 (2011)
PM ID: 21490069 PMC3082303 [Available on 05/15/12]
378: Zaro BW, Yang YY, Hang HC, Pratt MR
Chemical reporters for fluorescent detection and identification of O-GlcNAc-modified proteins reveal glycosylation of the ubiquitin ligase NEDD4-1.
Proc Natl Acad Sci U S A 108: 8146-51 (2011)
PM ID: 21540332 PMC3100932 [Available on 11/17/11]
379: Trojer P, Cao AR, Gao Z, Li Y, Zhang J, Xu X, Li G, Losson R, Erdjument-Bromage H, Tempst P, Farnham PJ, Reinberg D
L3MBTL2 protein acts in concert with PcG protein-mediated monoubiquitination of H2A to establish a repressive chromatin structure.
Mol Cell 42: 438-50 (2011)
PM ID: 21596310
380: Iyengar S, Ivanov AV, Jin VX, Rauscher FJ, Farnham PJ
Functional analysis of KAP1 genomic recruitment.
Mol Cell Biol 31: 1833-47 (2011)
PM ID: 21343339 PMC3133220 [Available on 11/01/11]
381: Oghamian S, Sodir NM, Bashir MU, Shen H, Cullins AE, Carroll CA, Kundu P, Shibata D, Laird PW
Reduction of pancreatic acinar cell tumor multiplicity in Dnmt1 hypomorphic mice.
Carcinogenesis 32: 829-35 (2011)
PM ID: 21362628 PMC3106433 [Available on 06/01/12]
382: Kim S, Wang M, Lee AS, Thompson RF
Impaired eyeblink conditioning in 78kDa-glucose regulated protein (GRP78)/immunoglobulin binding protein (BiP) conditional knockout mice.
Behav Neurosci 125: 404-11 (2011)
PM ID: 21517144
383: Cancer Genome Atlas Research Network
Integrated genomic analyses of ovarian carcinoma.
Nature 474: 609-15 (2011)
PM ID: 21720365
384: Freedman ML, Monteiro AN, Gayther SA, Coetzee GA, Risch A, Plass C, Casey G, De Biasi M, Carlson C, Duggan D, James M, Liu P, Tichelaar JW, Vikis HG, You M, Mills IG
Principles for the post-GWAS functional characterization of cancer risk loci.
Nat Genet 43: 513-8 (2011)
PM ID: 21614091
385: Weiss DJ, Bertoncello I, Borok Z, Kim C, Panoskaltsis-Mortari A, Reynolds S, Rojas M, Stripp B, Warburton D, Prockop DJ
Stem cells and cell therapies in lung biology and lung diseases.
Proc Am Thorac Soc 8: 223-72 (2011)
PM ID: 21653527 PMC3132784 [Available on 06/01/12]
386: Jiang TX, Tuan TL, Wu P, Widelitz RB, Chuong CM
From buds to follicles: Matrix metalloproteinases in developmental tissue remodeling during feather morphogenesis.
Differentiation 81: 307-14 (2011)
PM ID: 21497985 PMC3114260 [Available on 06/01/12] NIHMS286448 [Available on 06/01/12]
387: Siegmund KD
Statistical approaches for the analysis of DNA methylation microarray data.
Hum Genet 129: 585-95 (2011)
PM ID: 21519831
388: Borok Z, Whitsett JA, Bitterman PB, Thannickal VJ, Kotton DN, Reynolds SD, Krasnow MA, Bianchi DW, Morrisey EE, Hogan BL, Kurie JM, Walker DC, Radisky DC, Nishimura SL, Violette SM, Noble PW, Shapiro SD, Blaisdell CJ, Chapman HA, other participants
Cell Plasticity in Lung Injury and Repair: Report from an NHLBI Workshop, April 19-20, 2010.
Proc Am Thorac Soc 8: 215-22 (2011)
PM ID: 21653526 PMC3132783 [Available on 06/01/12]
389: Lyu J, Jho EH, Lu W
Smek promotes histone deacetylation to suppress transcription of Wnt target gene brachyury in pluripotent embryonic stem cells.
Cell Res 21: 911-21 (2011)
PM ID: 21423269
390: Iyengar S, Farnham PJ
KAP1: An enigmatic master regulator of the genome.
J Biol Chem : (2011)
PM ID: 21652716
391: Zhou H, Zhang Y, Fu Y, Chan L, Lee AS
Novel mechanism of anti-apoptotic function of 78-kDa glucose-regulated protein (GRP78): endocrine resistance factor in breast cancer, through release of B-cell lymphoma 2 (BCL-2) from BCL-2-interacting killer (BIK).
J Biol Chem 286: 25687-96 (2011)
PM ID: 21622563 PMC3138298 [Available on 07/22/12]
392: Breton CV, Byun HM, Wang X, Salam MT, Siegmund K, Gilliland FD
DNA methylation in the arginase-nitric oxide synthase pathway is associated with exhaled nitric oxide in children with asthma.
Am J Respir Crit Care Med 184: 191-7 (2011)
PM ID: 21512169 PMC3172885 [Available on 07/15/12]
393: Ji C, Kaplowitz N, Lau MY, Kao E, Petrovic LM, Lee AS
Liver-specific loss of glucose-regulated protein 78 perturbs the unfolded protein response and exacerbates a spectrum of liver diseases in mice.
Hepatology 54: 229-39 (2011)
PM ID: 21503947 PMC3125405 [Available on 07/01/12] NIHMS288241 [Available on 07/01/12]
394: Qiu X, Friedman JM, Liang G
Creating a flexible multiple microRNA expression vector by linking precursor microRNAs.
Biochem Biophys Res Commun 411: 276-80 (2011)
PM ID: 21726537 PMC3148277 [Available on 07/29/12] NIHMS307892 [Available on 07/29/12]
395: Park E, Gang EJ, Hsieh YT, Schaefer P, Chae S, Klemm L, Huantes S, Loh M, Conway EM, Kang ES, Hoe Koo H, Hofmann WK, Heisterkamp N, Pelus L, Keerthivasan G, Crispino J, Kahn M, Müschen M, Kim YM
Targeting survivin overcomes drug resistance in acute lymphoblastic leukemia.
Blood 118: 2191-9 (2011)
PM ID: 21715311 PMC3162353 [Available on 08/25/12]
396: Davis-Dao CA, Siegmund KD, Vandenberg DJ, Skinner EC, Coetzee GA, Thomas DC, Pike MC, Cortessis VK
Heterogenous effect of androgen receptor CAG tract length on testicular germ cell tumor risk: shorter repeats associated with seminoma but not other histologic types.
Carcinogenesis 32: 1238-43 (2011)
PM ID: 21642359 PMC3202310 [Available on 08/01/12]
397: Buchanan G, Need EF, Barrett JM, Bianco-Miotto T, Thompson VC, Butler LM, Marshall VR, Tilley WD, Coetzee GA
Corepressor effect on androgen receptor activity varies with the length of the CAG encoded polyglutamine repeat and is dependent on receptor/corepressor ratio in prostate cancer cells.
Mol Cell Endocrinol 342: 20-31 (2011)
PM ID: 21664238
398: Ye R, Ni M, Wang M, Luo S, Zhu G, Chow RH, Lee AS
Inositol 1,4,5-trisphosphate receptor 1 mutation perturbs glucose homeostasis and enhances susceptibility to diet-induced diabetes.
J Endocrinol 210: 209-17 (2011)
PM ID: 21565852 PMC3137733 [Available on 08/01/12] NIHMS298818 [Available on 08/01/12]
399: You JS, Kelly TK, De Carvalho DD, Taberlay PC, Liang G, Jones PA
OCT4 establishes and maintains nucleosome-depleted regions that provide additional layers of epigenetic regulation of its target genes.
Proc Natl Acad Sci U S A 108: 14497-502 (2011)
PM ID: 21844352 PMC3167525 [Available on 02/29/12]
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Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.
Nature 476: 214-9 (2011)
PM ID: 21833088 PMC3182531 [Available on 02/11/12]
401: Hinch AG, Tandon A, Patterson N, Song Y, Rohland N, Palmer CD, Chen GK, Wang K, Buxbaum SG, Akylbekova EL, Aldrich MC, Ambrosone CB, Amos C, Bandera EV, Berndt SI, Bernstein L, Blot WJ, Bock CH, Boerwinkle E, Cai Q, Caporaso N, Casey G, Cupples LA, Deming SL, Diver WR, Divers J, Fornage M, Gillanders EM, Glessner J, Harris CC, Hu JJ, Ingles SA, Isaacs W, John EM, Kao WH, Keating B, Kittles RA, Kolonel LN, Larkin E, Le Marchand L, McNeill LH, Millikan RC, Murphy A, Musani S, Neslund-Dudas C, Nyante S, Papanicolaou GJ, Press MF, Psaty BM, Reiner AP, Rich SS, Rodriguez-Gil JL, Rotter JI, Rybicki BA, Schwartz AG, Signorello LB, Spitz M, Strom SS, Thun MJ, Tucker MA, Wang Z, Wiencke JK, Witte JS, Wrensch M, Wu X, Yamamura Y, Zanetti KA, Zheng W, Ziegler RG, Zhu X, Redline S, Hirschhorn JN, Henderson BE, Taylor HA, Price AL, Hakonarson H, Chanock SJ, Haiman CA, Wilson JG, Reich D, Myers SR
The landscape of recombination in African Americans.
Nature 476: 170-5 (2011)
PM ID: 21775986 PMC3154982 [Available on 02/11/12] NIHMS313104 [Available on 02/11/12]
402: Lee G, Liang C, Park G, Jang C, Jung JU, Chung J
UVRAG is required for organ rotation by regulating Notch endocytosis in Drosophila.
Dev Biol 356: 588-97 (2011)
PM ID: 21729695
403: Zhong Q, Zhou B, Ann DK, Minoo P, Liu Y, Banfalvi A, Krishnaveni MS, Dubourd M, Demaio L, Willis BC, Kim KJ, Dubois RM, Crandall ED, Beers MF, Borok Z
Role of endoplasmic reticulum stress in epithelial-mesenchymal transition of alveolar epithelial cells: effects of misfolded surfactant protein.
Am J Respir Cell Mol Biol 45: 498-509 (2011)
PM ID: 21169555 PMC3175581 [Available on 09/01/12]
404: Ji Yu E, Kim SH, Heo K, Ou CY, Stallcup MR, Kim JH
Reciprocal roles of DBC1 and SIRT1 in regulating estrogen receptor {alpha} activity and co-activator synergy.
Nucleic Acids Res 39: 6932-43 (2011)
PM ID: 21596782 PMC3167635
405: Zaro BW, Bateman LA, Pratt MR
Robust in-gel fluorescence detection of mucin-type O-linked glycosylation.
Bioorg Med Chem Lett 21: 5062-6 (2011)
PM ID: 21531554
406: Li W, Sahu D, Tsen F
Secreted heat shock protein-90 (Hsp90) in wound healing and cancer.
Biochim Biophys Acta : (2011)
PM ID: 21982864
407: Wang J, Siegmund K, Tseng CC, Lee AS, Wu AH
Soy food supplementation, dietary fat reduction and peripheral blood gene expression in postmenopausal women--a randomized, controlled trial.
Mol Nutr Food Res 55 Suppl 2: S264-77 (2011)
PM ID: 21823222
408: Fazlollahi F, Angelow S, Yacobi NR, Marchelletta R, Yu AS, Hamm-Alvarez SF, Borok Z, Kim KJ, Crandall ED
Polystyrene nanoparticle trafficking across MDCK-II.
Nanomedicine 7: 588-94 (2011)
PM ID: 21310266 PMC3130091 [Available on 10/01/12] NIHMS273797 [Available on 10/01/12]
409: Kim H, Heo K, Choi J, Kim K, An W
Histone variant H3.3 stimulates HSP70 transcription through cooperation with HP1γ.
Nucleic Acids Res 39: 8329-41 (2011)
PM ID: 21742762 PMC3201866
410: Baylin SB, Jones PA
A decade of exploring the cancer epigenome - biological and translational implications.
Nat Rev Cancer 11: 726-34 (2011)
PM ID: 21941284
411: Kahn M
Symmetric division versus asymmetric division: a tale of two coactivators.
Future Med Chem 3: 1745-63 (2011)
PM ID: 22004083
412: Winder T, Bohanes P, Zhang W, Yang D, Power DG, Ning Y, Gerger A, Wilson PM, Tang LH, Shah M, Lee AS, Lenz HJ
GRP78 promoter polymorphism rs391957 as potential predictor for clinical outcome in gastric and colorectal cancer patients.
Ann Oncol 22: 2431-9 (2011)
PM ID: 21382870 PMC3200220 [Available on 11/01/12]
413: Miki T, Yasuda SY, Kahn M
Wnt/β-catenin signaling in embryonic stem cell self-renewal and somatic cell reprogramming.
Stem Cell Rev 7: 836-46 (2011)
PM ID: 21603945
414: Han H, Cortez CC, Yang X, Nichols PW, Jones PA, Liang G
DNA methylation directly silences genes with non-CpG island promoters and establishes a nucleosome occupied promoter.
Hum Mol Genet 20: 4299-310 (2011)
PM ID: 21835883 PMC3196883 [Available on 11/15/12]
415: Gerger A, Zhang W, Yang D, Bohanes P, Ning Y, Winder T, LaBonte MJ, Wilson PM, Benhaim L, Paez D, El-Khoueiry R, El-Khoueiry A, Kahn M, Lenz HJ
Common cancer stem cell gene variants predict colon cancer recurrence.
Clin Cancer Res 17: 6934-43 (2011)
PM ID: 21918173
416: Cheng CF, Sahu D, Tsen F, Zhao Z, Fan J, Kim R, Wang X, O'Brien K, Li Y, Kuang Y, Chen M, Woodley DT, Li W
A fragment of secreted Hsp90α carries properties that enable it to accelerate effectively both acute and diabetic wound healing in mice.
J Clin Invest 121: 4348-61 (2011)
PM ID: 22019588 PMC3204835
417: Choi J, Kim H, Kim K, Lee B, Lu W, An W
Selective requirement of H2B N-Terminal tail for p14ARF-induced chromatin silencing.
Nucleic Acids Res 39: 9167-80 (2011)
PM ID: 21846774 PMC3241654
418: Zada G, Bond AE, Wang YP, Giannotta SL, Deapen D
Incidence Trends in the Anatomic Location of Primary Malignant Brain Tumors in the United States: 1992-2006.
World Neurosurg : (2011)
PM ID: 22120376
419: Purcell DJ, Jeong KW, Bittencourt D, Gerke DS, Stallcup MR
A distinct mechanism for coactivator versus corepressor function by histone methyltransferase G9a in transcriptional regulation.
J Biol Chem 286: 41963-71 (2011)
PM ID: 21984853 PMC3234941 [Available on 12/09/12]
420: Andreu-Vieyra C, Lai J, Berman BP, Frenkel B, Jia L, Jones PA, Coetzee GA
Dynamic nucleosome-depleted regions at androgen receptor enhancers in the absence of ligand in prostate cancer cells.
Mol Cell Biol 31: 4648-62 (2011)
PM ID: 21969603 PMC3232925 [Available on 06/01/12]
421: Shibata D
Molecular tumor clocks to study the evolution of drug resistance.
Mol Pharm 8: 2050-4 (2011)
PM ID: 21732670
422: Tian Y, Sir D, Kuo CF, Ann DK, Ou JH
Autophagy required for hepatitis B virus replication in transgenic mice.
J Virol 85: 13453-6 (2011)
PM ID: 21957292 PMC3233133 [Available on 06/01/12]
423: Razzak AA, Oxentenko AS, Vierkant RA, Tillmans LS, Wang AH, Weisenberger DJ, Laird PW, Lynch CF, Anderson KE, French AJ, Haile RW, Harnack LJ, Slager SL, Smyrk TC, Thibodeau SN, Cerhan JR, Limburg PJ
Alcohol intake and colorectal cancer risk by molecularly defined subtypes in a prospective study of older women.
Cancer Prev Res (Phila) 4: 2035-43 (2011)
PM ID: 21900595
424: Cortessis VK, Siegmund K, Houshdaran S, Laird PW, Sokol RZ
Repeated assessment by high-throughput assay demonstrates that sperm DNA methylation levels are highly reproducible.
Fertil Steril 96: 1325-30 (2011)
PM ID: 22035967
425: Zeng N, Li Y, He L, Xu X, Galicia V, Deng C, Stiles BL
Adaptive basal phosphorylation of eIF2α is responsible for resistance to cellular stress-induced cell death in Pten-null hepatocytes.
Mol Cancer Res 9: 1708-17 (2011)
PM ID: 22009178
426: Jeong KW, Kim K, Situ AJ, Ulmer TS, An W, Stallcup MR
Recognition of enhancer element-specific histone methylation by TIP60 in transcriptional activation.
Nat Struct Mol Biol 18: 1358-65 (2011)
PM ID: 22081016 PMC3230772 [Available on 05/13/12] NIHMS321138 [Available on 05/13/12]
427: Taberlay PC, Kelly TK, Liu CC, You JS, De Carvalho DD, Miranda TB, Zhou XJ, Liang G, Jones PA
Polycomb-repressed genes have permissive enhancers that initiate reprogramming.
Cell 147: 1283-94 (2011)
PM ID: 22153073 PMC3240866 [Available on 12/09/12] NIHMS338207 [Available on 12/09/12]
428: Noushmehr H, Coetzee GA
Identification and functional annotation of GWAS risk SNPs.
Cell Cycle 10: 3995-6 (2011)
PM ID: 22101276
429: International Stem Cell Initiative , Amps K, Andrews PW, Anyfantis G, Armstrong L, Avery S, Baharvand H, Baker J, Baker D, Munoz MB, Beil S, Benvenisty N, Ben-Yosef D, Biancotti JC, Bosman A, Brena RM, Brison D, Caisander G, Camarasa MV, Chen J, Chiao E, Choi YM, Choo AB, Collins D, Colman A, Crook JM, Daley GQ, Dalton A, De Sousa PA, Denning C, Downie J, Dvorak P, Montgomery KD, Feki A, Ford A, Fox V, Fraga AM, Frumkin T, Ge L, Gokhale PJ, Golan-Lev T, Gourabi H, Gropp M, Lu G, Hampl A, Harron K, Healy L, Herath W, Holm F, Hovatta O, Hyllner J, Inamdar MS, Irwanto AK, Ishii T, Jaconi M, Jin Y, Kimber S, Kiselev S, Knowles BB, Kopper O, Kukharenko V, Kuliev A, Lagarkova MA, Laird PW, Lako M, Laslett AL, Lavon N, Lee DR, Lee JE, Li C, Lim LS, Ludwig TE, Ma Y, Maltby E, Mateizel I, Mayshar Y, Mileikovsky M, Minger SL, Miyazaki T, Moon SY, Moore H, Mummery C, Nagy A, Nakatsuji N, Narwani K, Oh SK, Oh SK, Olson C, Otonkoski T, Pan F, Park IH, Pells S, Pera MF, Pereira LV, Qi O, Raj GS, Reubinoff B, Robins A, Robson P, Rossant J, Salekdeh GH, Schulz TC, Sermon K, Sheik Mohamed J, Shen H, Sherrer E, Sidhu K, Sivarajah S, Skottman H, Spits C, Stacey GN, Strehl R, Strelchenko N, Suemori H, Sun B, Suuronen R, Takahashi K, Tuuri T, Venu P, Verlinsky Y, Ward-van Oostwaard D, Weisenberger DJ, Wu Y, Yamanaka S, Young L, Zhou Q
Screening ethnically diverse human embryonic stem cells identifies a chromosome 20 minimal amplicon conferring growth advantage.
Nat Biotechnol 29: 1132-44 (2011)
PM ID: 22119741
430: Kennedy BA, Lan X, Huang TH, Farnham PJ, Jin VX
Using ChIPMotifs for de novo motif discovery of OCT4 and ZNF263 based on ChIP-based high-throughput experiments.
Methods Mol Biol 802: 323-34 (2012)
PM ID: 22130890
431: Brusslan JA, Rus Alvarez-Canterbury AM, Nair NU, Rice JC, Hitchler MJ, Pellegrini M
Genome-wide evaluation of histone methylation changes associated with leaf senescence in Arabidopsis.
PLoS One 7: e33151 (2012)
PM ID: 22427974 PMC3299739
432: Zhou B, Buckley ST, Patel V, Liu Y, Luo J, Krishnaveni MS, Ivan M, Demaio L, Kim KJ, Ehrhardt C, Crandall ED, Borok Z
Troglitazone Attenuates TGF-β1-Induced EMT in Alveolar Epithelial Cells via a PPARγ-Independent Mechanism.
PLoS One 7: e38827 (2012)
PM ID: 22745681 PMC3380041
433: Wey S, Luo B, Lee AS
Acute Inducible Ablation of GRP78 Reveals Its Role in Hematopoietic Stem Cell Survival, Lymphogenesis and Regulation of Stress Signaling.
PLoS One 7: e39047 (2012)
PM ID: 22723926 PMC3377598
434: Han H, Wolff EM, Liang G
Epigenetic Alterations in Bladder Cancer and Their Potential Clinical Implications.
Adv Urol 2012: 546917 (2012)
PM ID: 22829811
435: Razzak AA, Oxentenko AS, Vierkant RA, Tillmans LS, Wang AH, Weisenberger DJ, Laird PW, Lynch CF, Anderson KE, French AJ, Haile RW, Harnack LJ, Potter JD, Slager SL, Smyrk TC, Thibodeau SN, Cerhan JR, Limburg PJ
Associations between intake of folate and related micronutrients with molecularly defined colorectal cancer risks in the Iowa Women's Health Study.
Nutr Cancer 64: 899-910 (2012)
PM ID: 23061900
436: Lange CP, Campan M, Hinoue T, Schmitz RF, van der Meulen-de Jong AE, Slingerland H, Kok PJ, van Dijk CM, Weisenberger DJ, Shen H, Tollenaar RA, Laird PW
Genome-scale discovery of DNA-methylation biomarkers for blood-based detection of colorectal cancer.
PLoS One 7: e50266 (2012)
PM ID: 23209692 PMC3508917
437: Wey S, Luo B, Tseng CC, Ni M, Zhou H, Fu Y, Bhojwani D, Carroll WL, Lee AS
Inducible knockout of GRP78/BiP in the hematopoietic system suppresses Pten-null leukemogenesis and AKT oncogenic signaling.
Blood 119: 817-25 (2012)
PM ID: 21937694 PMC3265205 [Available on 01/19/13]
438: Sharma S, Gerke DS, Han HF, Jeong S, Stallcup MR, Jones PA, Liang G
Lysine Methyltransferase G9a is Not Required for DNMT3A/3B Anchoring to Methylated Nucleosomes and Maintenance of DNA Methylation in Somatic Cells.
Epigenetics Chromatin 5: 3 (2012)
PM ID: 22284370
439: Treppendahl MB, Qiu X, Søgaard A, Yang X, Nandrup-Bus C, Hother C, Andersen MK, Kjeldsen L, Möllgaard L, Hellström-Lindberg E, Jendholm J, Porse BT, Jones PA, Liang G, Grønbaek K
Allelic methylation levels of the noncoding VTRNA2-1 located on chromosome 5q31.1 predict outcome in AML.
Blood 119: 206-16 (2012)
PM ID: 22058117 PMC3251229 [Available on 01/05/13]
440: Coetzee GA
The usefulness of prostate cancer genome-wide association studies.
J Urol 187: 9-10 (2012)
PM ID: 22088348
441: Pohl A, El-Khoueiry A, Yang D, Zhang W, Lurje G, Ning Y, Winder T, Hu-Lieskoven S, Iqbal S, Danenberg KD, Kahn M, Teo JL, Shriki J, Stebbing J, Lenz HJ
Pharmacogenetic profiling of CD133 is associated with response rate (RR) and progression-free survival (PFS) in patients with metastatic colorectal cancer (mCRC), treated with bevacizumab-based chemotherapy.
Pharmacogenomics J : (2012)
PM ID: 22231565
442: Berman BP, Weisenberger DJ, Aman JF, Hinoue T, Ramjan Z, Liu Y, Noushmehr H, Lange CP, van Dijk CM, Tollenaar RA, Van Den Berg D, Laird PW
Regions of focal DNA hypermethylation and long-range hypomethylation in colorectal cancer coincide with nuclear lamina-associated domains.
Nat Genet 44: 40-6 (2012)
PM ID: 22120008
443: Iwata J, Tung L, Urata M, Hacia JG, Pelikan R, Suzuki A, Ramenzoni L, Chaudhry O, Parada C, Sanchez-Lara PA, Chai Y
Fibroblast growth factor 9 (FGF9)-pituitary homeobox 2 (PITX2) pathway mediates transforming growth factor β (TGFβ) signaling to regulate cell proliferation in palatal mesenchyme during mouse palatogenesis.
J Biol Chem 287: 2353-63 (2012)
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444: Kang YA, Sanalkumar R, O'Geen H, Linnemann AK, Chang CJ, Bouhassira EE, Farnham PJ, Keles S, Bresnick EH
Autophagy driven by a master regulator of hematopoiesis.
Mol Cell Biol 32: 226-39 (2012)
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445: Hinoue T, Weisenberger DJ, Lange CP, Shen H, Byun HM, Van Den Berg D, Malik S, Pan F, Noushmehr H, van Dijk CM, Tollenaar RA, Laird PW
Genome-scale analysis of aberrant DNA methylation in colorectal cancer.
Genome Res 22: 271-82 (2012)
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446: Jenkins G, Blanchard A, Borok Z, Bradding P, Ehrhardt C, Fisher A, Hirani N, Johnson S, Königshoff M, Maher TM, Millar A, Parfrey H, Scotton C, Tetley T, Thickett D, Wolters P, ECIPF workshop
In search of the fibrotic epithelial cell: opportunities for a collaborative network.
Thorax 67: 179-82 (2012)
PM ID: 21680569
447: Ianculescu I, Wu DY, Siegmund KD, Stallcup MR
Selective roles for cAMP response element-binding protein binding protein and p300 protein as coregulators for androgen-regulated gene expression in advanced prostate cancer cells.
J Biol Chem 287: 4000-13 (2012)
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448: Levine AJ, Win AK, Buchanan DD, Jenkins MA, Baron JA, Young JP, Long TI, Weisenberger DJ, Laird PW, McCall RL, Duggan DJ, Haile RW
Cancer risks for the relatives of colorectal cancer cases with a methylated MLH1 promoter region: data from the Colorectal Cancer Family Registry.
Cancer Prev Res (Phila) 5: 328-35 (2012)
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449: Sahu D, Zhao Z, Tsen F, Cheng CF, Park R, Situ AJ, Dai J, Eginli A, Shams S, Chen M, Ulmer TS, Conti P, Woodley DT, Li W
A potentially common peptide target in secreted heat shock protein-90α for hypoxia-inducible factor-1α-positive tumors.
Mol Biol Cell 23: 602-13 (2012)
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450: Kim K, Heo K, Choi J, Jackson S, Kim H, Xiong Y, An W
Vpr-Binding Protein Antagonizes p53-Mediated Transcription via Direct Interaction with H3 Tail.
Mol Cell Biol 32: 783-96 (2012)
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451: Kim H, Kim K, Choi J, Heo K, Baek HJ, Roeder RG, An W
p53 requires an intact C-terminal domain for DNA binding and transactivation.
J Mol Biol 415: 843-54 (2012)
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452: Choi I, Lee S, Kyoung Chung H, Suk Lee Y, Eui Kim K, Choi D, Park EK, Yang D, Ecoiffier T, Monahan J, Chen W, Aguilar B, Lee HN, Yoo J, Koh CJ, Chen L, Wong AK, Hong YK
9-cis retinoic Acid promotes lymphangiogenesis and enhances lymphatic vessel regeneration: therapeutic implications of 9-cis retinoic Acid for secondary lymphedema.
Circulation 125: 872-82 (2012)
PM ID: 22275501
453: Liang C
Viral FLIPping autophagy for longevity.
Cell Host Microbe 11: 101-3 (2012)
PM ID: 22341458
454: Demaio L, Buckley ST, Krishnaveni MS, Flodby P, Dubourd M, Banfalvi A, Xing Y, Ehrhardt C, Minoo P, Zhou B, Crandall ED, Borok Z
Ligand-independent transforming growth factor-β type I receptor signalling mediates type I collagen-induced epithelial-mesenchymal transition.
J Pathol 226: 633-44 (2012)
PM ID: 21984393
455: Davis-Dao C, Koh CJ, Hardy BE, Chang A, Kim SS, De Filippo R, Hwang A, Pike MC, Carroll JD, Coetzee GA, VanDenBerg D, Siegmund K, Cortessis VK
Shorter androgen receptor CAG repeat lengths associated with cryptorchidism risk among Hispanic white boys.
J Clin Endocrinol Metab 97: E393-9 (2012)
PM ID: 22188741
456: Zhou B, Liu Y, Kahn M, Ann DK, Han A, Wang H, Nguyen C, Flodby P, Zhong Q, Krishnaveni MS, Liebler JM, Minoo P, Crandall ED, Borok Z
Interactions between β-catenin and transforming growth factor-β signaling pathways mediate epithelial-mesenchymal transition and are dependent on the transcriptional co-activator cAMP-response element-binding protein (CREB)-binding protein (CBP).
J Biol Chem 287: 7026-38 (2012)
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457: Iwata J, Hacia JG, Suzuki A, Sanchez-Lara PA, Urata M, Chai Y
Modulation of noncanonical TGF-β signaling prevents cleft palate in Tgfbr2 mutant mice.
J Clin Invest 122: 873-85 (2012)
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458: Lin HH, Li X, Chen JL, Sun X, Cooper FN, Chen YR, Zhang W, Chung Y, Li A, Cheng CT, Yang L, Deng X, Liu X, Yen Y, Johnson DL, Shih HM, Yang A, Ann DK
Identification of an AAA ATPase VPS4B-dependent pathway that modulates epidermal growth factor receptor abundance and signaling during hypoxia.
Mol Cell Biol 32: 1124-38 (2012)
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459: Yang X, Noushmehr H, Han H, Andreu-Vieyra C, Liang G, Jones PA
Gene reactivation by 5-aza-2'-deoxycytidine-induced demethylation requires SRCAP-mediated H2A.Z insertion to establish nucleosome depleted regions.
PLoS Genet 8: e1002604 (2012)
PM ID: 22479200 PMC3315468
460: Meier F, Abeywardana T, Dhall A, Marotta NP, Varkey J, Langen R, Chatterjee C, Pratt MR
Semisynthetic, Site-Specific Ubiquitin Modification of α-Synuclein Reveals Differential Effects on Aggregation.
J Am Chem Soc 134: 5468-71 (2012)
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461: Yusuf D, Butland SL, Swanson MI, Bolotin E, Ticoll A, Cheung WA, Zhang XY, Dickman CT, Fulton DL, Lim JS, Schnabl JM, Ramos OH, Vasseur-Cognet M, de Leeuw CN, Simpson EM, Ryffel GU, Lam EW, Kist R, Wilson MS, Marco-Ferreres R, Brosens JJ, Beccari LL, Bovolenta P, Benayoun BA, Monteiro LJ, Schwenen HD, Grontved L, Wederell E, Mandrup S, Veitia RA, Chakravarthy H, Hoodless PA, Mancarelli M, Torbett BE, Banham AH, Reddy SP, Cullum RL, Liedtke M, Tschan MP, Vaz M, Rizzino A, Zannini M, Frietze S, Farnham PJ, Eijkelenboom A, Brown PJ, Laperriere D, Leprince D, de Cristofaro T, Prince KL, Putker M, Del Peso L, Camenisch G, Wenger RH, Mikula M, Rozendaal M, Mader S, Ostrowski J, Rhodes SJ, Van Rechem C, Boulay G, Olechnowicz SW, Breslin MB, Lan MS, Nanan KK, Wegner M, Hou J, Mullen RD, Colvin SC, Noy PJ, Webb CF, Witek ME, Ferrell S, Daniel JM, Park J, Waldman SA, Peet DJ, Taggart M, Jayaraman PS, Karrich JJ, Blom B, Vesuna F, O'Geen H, Sun Y, Gronostajski RM, Woodcroft MW, Hough MR, Chen E, Europe-Finner N, Karolczak-Bayatti M, Bailey J, Hankinson O, Raman V, Lebrun DP, Biswal S, Harvey CJ, Debruyne JP, Hogenesch JB, Hevner RF, Heligon C, Luo XM, Blank MC, Millen KJ, Sharlin DS, Forrest D, Dahlman-Wright K, Zhao C, Mishima Y, Sinha S, Chakrabarti R, Portales-Casamar E, Sladek FM, Bradley PH, Wasserman WW
The Transcription Factor Encyclopedia.
Genome Biol 13: R24 (2012)
PM ID: 22458515
462: Yang CS, Lee JS, Rodgers M, Min CK, Lee JY, Kim HJ, Lee KH, Kim CJ, Oh B, Zandi E, Yue Z, Kramnik I, Liang C, Jung JU
Autophagy protein Rubicon mediates phagocytic NADPH oxidase activation in response to microbial infection or TLR stimulation.
Cell Host Microbe 11: 264-76 (2012)
PM ID: 22423966
463: Wang J, Joshi AD, Corral R, Siegmund KD, Marchand LL, Martinez ME, Haile RW, Ahnen DJ, Sandler RS, Lance P, Stern MC
Carcinogen metabolism genes, red meat and poultry intake, and colorectal cancer risk.
Int J Cancer 130: 1898-907 (2012)
PM ID: 21618522
464: Fischer JM, Miller AJ, Shibata D, Liskay RM
Different phenotypic consequences of simultaneous versus stepwise Apc loss.
Oncogene 31: 2028-38 (2012)
PM ID: 21892206 PMC3235266 [Available on 10/19/12] NIHMS315854 [Available on 10/19/12]
465: Little GH, Noushmehr H, Baniwal SK, Berman BP, Coetzee GA, Frenkel B
Genome-wide Runx2 occupancy in prostate cancer cells suggests a role in regulating secretion.
Nucleic Acids Res 40: 3538-47 (2012)
PM ID: 22187159 PMC3333873
466: Yoo SA, You S, Yoon HJ, Kim DH, Kim HS, Lee K, Ahn JH, Hwang D, Lee AS, Kim KJ, Park YJ, Cho CS, Kim WU
A novel pathogenic role of the ER chaperone GRP78/BiP in rheumatoid arthritis.
J Exp Med 209: 871-86 (2012)
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467: Zhang H, Liu H, Borok Z, Davies KJ, Ursini F, Forman HJ
Cigarette smoke extract stimulates epithelial-mesenchymal transition through Src activation.
Free Radic Biol Med 52: 1437-42 (2012)
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468: Shibata D
Cancer. Heterogeneity and tumor history.
Science 336: 304-5 (2012)
PM ID: 22517848
469: Kerin T, Ramanathan A, Rivas K, Grepo N, Coetzee GA, Campbell DB
A noncoding RNA antisense to moesin at 5p14.1 in autism.
Sci Transl Med 4: 128ra40 (2012)
PM ID: 22491950
470: Shen H, Laird PW
In epigenetic therapy, less is more.
Cell Stem Cell 10: 353-4 (2012)
PM ID: 22482500
471: Chuong CM, Randall VA, Widelitz RB, Wu P, Jiang TX
Physiological regeneration of skin appendages and implications for regenerative medicine.
Physiology (Bethesda) 27: 61-72 (2012)
PM ID: 22505663
472: Ting MC, Liao CP, Yan C, Jia L, Groshen S, Frenkel B, Roy-Burman P, Coetzee GA, Maxson R
An enhancer from the 8q24 prostate cancer risk region is sufficient to direct reporter gene expression to a subset of prostate stem-like epithelial cells in transgenic mice.
Dis Model Mech 5: 366-74 (2012)
PM ID: 22279083 PMC3339830
473: Han D, Zhao H, Parada C, Hacia JG, Bringas P, Chai Y
A TGFβ-Smad4-Fgf6 signaling cascade controls myogenic differentiation and myoblast fusion during tongue development.
Development 139: 1640-50 (2012)
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474: Xing Y, Li A, Borok Z, Li C, Minoo P
NOTCH1 is required for regeneration of Clara cells during repair of airway injury.
Stem Cells 30: 946-55 (2012)
PM ID: 22331706
475: Carter SL, Cibulskis K, Helman E, McKenna A, Shen H, Zack T, Laird PW, Onofrio RC, Winckler W, Weir BA, Beroukhim R, Pellman D, Levine DA, Lander ES, Meyerson M, Getz G
Absolute quantification of somatic DNA alterations in human cancer.
Nat Biotechnol 30: 413-21 (2012)
PM ID: 22544022
476: Zhao Z, Oh S, Li D, Ni D, Pirooz SD, Lee JH, Yang S, Lee JY, Ghozalli I, Costanzo V, Stark JM, Liang C
A Dual Role for UVRAG in Maintaining Chromosomal Stability Independent of Autophagy.
Dev Cell 22: 1001-16 (2012)
PM ID: 22542840 PMC3356442 [Available on 05/15/13] NIHMS367824 [Available on 05/15/13]
477: De Carvalho DD, Sharma S, You JS, Su SF, Taberlay PC, Kelly TK, Yang X, Liang G, Jones PA
DNA methylation screening identifies driver epigenetic events of cancer cell survival.
Cancer Cell 21: 655-67 (2012)
PM ID: 22624715
478: Jung CJ, Iyengar S, Blahnik KR, Jiang JX, Tahimic C, Torok NJ, De Vere White RW, Farnham PJ, Zern M
Human ESC Self-Renewal Promoting miRNAs Induce Epithelial-Mesenchymal Transition in Hepatocytes by Controlling the PTEN and TGFβ Tumor Suppressor Signaling Pathways.
Mol Cancer Res : (2012)
PM ID: 22622027
479: Breton CV, Salam MT, Wang X, Byun HM, Siegmund KD, Gilliland FD
Particulate Matter, DNA Methylation in Nitric Oxide Synthase, and Childhood Respiratory Disease.
Environ Health Perspect : (2012)
PM ID: 22591701
480: Tsai AG, Chen DM, Lin M, Hsieh JC, Okitsu CY, Taghva A, Shibata D, Hsieh CL
Heterogeneity and randomness of DNA methylation patterns in human embryonic stem cells.
DNA Cell Biol 31: 893-907 (2012)
PM ID: 22277069
481: Won Jeong K, Chodankar R, Purcell DJ, Bittencourt D, Stallcup MR
Gene-specific patterns of coregulator requirements by estrogen receptor-α in breast cancer cells.
Mol Endocrinol 26: 955-66 (2012)
PM ID: 22543272 PMC3355545
482: Yen HY, Gabet Y, Liu Y, Martin A, Wu NL, Pike MC, Frenkel B, Maxson R, Dubeau L
Alterations in Brca1 expression in mouse ovarian granulosa cells have short-term and long-term consequences on estrogen-responsive organs.
Lab Invest 92: 802-11 (2012)
PM ID: 22488153
483: Lam G, Mehta V, Zada G
Spontaneous and medically induced cerebrospinal fluid leakage in the setting of pituitary adenomas: review of the literature.
Neurosurg Focus 32: E2 (2012)
PM ID: 22655691
484: Purcell DJ, Khalid O, Ou CY, Little GH, Frenkel B, Baniwal SK, Stallcup MR
Recruitment of coregulator G9a by Runx2 for selective enhancement or suppression of transcription.
J Cell Biochem 113: 2406-14 (2012)
PM ID: 22389001 PMC3350606 [Available on 07/01/13] NIHMS363705 [Available on 07/01/13]
485: Jones PA
Functions of DNA methylation: islands, start sites, gene bodies and beyond.
Nat Rev Genet 13: 484-92 (2012)
PM ID: 22641018
486: Selamat SA, Chung BS, Girard L, Zhang W, Zhang Y, Campan M, Siegmund KD, Koss MN, Hagen JA, Lam WL, Lam S, Gazdar AF, Laird-Offringa IA
Genome-scale analysis of DNA methylation in lung adenocarcinoma and integration with mRNA expression.
Genome Res 22: 1197-211 (2012)
PM ID: 22613842 PMC3396362
487: You JS, Jones PA
Cancer genetics and epigenetics: two sides of the same coin?
Cancer Cell 22: 9-20 (2012)
PM ID: 22789535 PMC3396881 NIHMS388188
488: Ng CS, Wu P, Foley J, Foley A, McDonald ML, Juan WT, Huang CJ, Lai YT, Lo WS, Chen CF, Leal SM, Zhang H, Widelitz RB, Patel PI, Li WH, Chuong CM
The Chicken Frizzle Feather Is Due to an α-Keratin (KRT75) Mutation That Causes a Defective Rachis.
PLoS Genet 8: e1002748 (2012)
PM ID: 22829773 PMC3400578
489: Liu Y, Siegmund KD, Laird PW, Berman BP
Bis-SNP: Combined DNA methylation and SNP calling for Bisulfite-seq data.
Genome Biol 13: R61 (2012)
PM ID: 22784381
490: Heo K, Kim JS, Kim K, Kim H, Choi J, Yang K, An W
Cell-penetrating H4 tail peptides potentiate p53-mediated transactivation via inhibition of G9a and HDAC1.
Oncogene : (2012)
PM ID: 22751130
491: Chang JS, Ocvirk S, Berger E, Kisling S, Binder U, Skerra A, Lee AS, Haller D
Endoplasmic reticulum stress response promotes cytotoxic phenotype of CD8αβ+ intraepithelial lymphocytes in a mouse model for Crohn's disease-like ileitis.
J Immunol 189: 1510-20 (2012)
PM ID: 22753943
492: Nguyen TJ, Costa MA, Vidar EN, Shahabi A, Peric M, Hernandez AM, Chan LS, Sener SF, Wong AK
Effect of immediate reconstruction on postmastectomy surgical site infection.
Ann Surg 256: 326-33 (2012)
PM ID: 22791106
493: Zada G, Tirosh A, Huang AP, Laws ER, Woodmansee WW
The postoperative cortisol stress response following transsphenoidal pituitary surgery: a potential screening method for assessing preserved pituitary function.
Pituitary : (2012)
PM ID: 22915289
494: Limsui D, Vierkant RA, Tillmans LS, Wang AH, Weisenberger DJ, Laird PW, Lynch CF, Anderson KE, French AJ, Haile RW, Harnack LJ, Potter JD, Slager SL, Smyrk TC, Thibodeau SN, Cerhan JR, Limburg PJ
Postmenopausal hormone therapy and colorectal cancer risk by molecularly defined subtypes among older women.
Gut 61: 1299-305 (2012)
PM ID: 22027477
495: Kim K, Jeong KW, Kim H, Choi J, Lu W, Stallcup MR, An W
Functional interplay between p53 acetylation and H1.2 phosphorylation in p53-regulated transcription.
Oncogene 31: 4290-301 (2012)
PM ID: 22249259 PMC3330162 NIHMS341053
496: Farnham PJ
Thematic Minireview Series on Results from the ENCODE Project: Integrative Global Analyses of Regulatory Regions in the Human Genome.
J Biol Chem 287: 30885-7 (2012)
PM ID: 22451669 PMC3438920
497: Brulois KF, Chang H, Lee AS, Ensser A, Wong LY, Toth Z, Lee SH, Lee HR, Myoung J, Ganem D, Oh TK, Kim JF, Gao SJ, Jung JU
Construction and manipulation of a new Kaposi's sarcoma-associated herpesvirus bacterial artificial chromosome clone.
J Virol 86: 9708-20 (2012)
PM ID: 22740391 PMC3446615
498: Lan X, Witt H, Katsumura K, Ye Z, Wang Q, Bresnick EH, Farnham PJ, Jin VX
Integration of Hi-C and ChIP-seq data reveals distinct types of chromatin linkages.
Nucleic Acids Res 40: 7690-7704 (2012)
PM ID: 22675074
499: Yu EJ, Kim SH, Kim MJ, Seo WY, Song KA, Kang MS, Yang CK, Stallcup MR, Kim JH
SUMOylation of ZFP282 potentiates its positive effect on estrogen signaling in breast tumorigenesis.
Oncogene : (2012)
PM ID: 22986521
500: Li J, Jiang TX, Hughes MW, Wu P, Yu J, Widelitz RB, Fan G, Chuong CM
Progressive Alopecia Reveals Decreasing Stem Cell Activation Probability during Aging of Mice with Epidermal Deletion of DNA Methyltransferase 1.
J Invest Dermatol : (2012)
PM ID: 22992801
501: Pratt MR
Small-molecule reprogramming of cancer metabolism.
Chem Biol 19: 1084-5 (2012)
PM ID: 22999876
502: Landt SG, Marinov GK, Kundaje A, Kheradpour P, Pauli F, Batzoglou S, Bernstein BE, Bickel P, Brown JB, Cayting P, Chen Y, Desalvo G, Epstein C, Fisher-Aylor KI, Euskirchen G, Gerstein M, Gertz J, Hartemink AJ, Hoffman MM, Iyer VR, Jung YL, Karmakar S, Kellis M, Kharchenko PV, Li Q, Liu T, Liu XS, Ma L, Milosavljevic A, Myers RM, Park PJ, Pazin MJ, Perry MD, Raha D, Reddy TE, Rozowsky J, Shoresh N, Sidow A, Slattery M, Stamatoyannopoulos JA, Tolstorukov MY, White KP, Xi S, Farnham PJ, Lieb JD, Wold BJ, Snyder M
ChIP-seq guidelines and practices of the ENCODE and modENCODE consortia.
Genome Res 22: 1813-31 (2012)
PM ID: 22955991 PMC3431496
503: Gerstein MB, Kundaje A, Hariharan M, Landt SG, Yan KK, Cheng C, Mu XJ, Khurana E, Rozowsky J, Alexander R, Min R, Alves P, Abyzov A, Addleman N, Bhardwaj N, Boyle AP, Cayting P, Charos A, Chen DZ, Cheng Y, Clarke D, Eastman C, Euskirchen G, Frietze S, Fu Y, Gertz J, Grubert F, Harmanci A, Jain P, Kasowski M, Lacroute P, Leng J, Lian J, Monahan H, O'Geen H, Ouyang Z, Partridge EC, Patacsil D, Pauli F, Raha D, Ramirez L, Reddy TE, Reed B, Shi M, Slifer T, Wang J, Wu L, Yang X, Yip KY, Zilberman-Schapira G, Batzoglou S, Sidow A, Farnham PJ, Myers RM, Weissman SM, Snyder M
Architecture of the human regulatory network derived from ENCODE data.
Nature 489: 91-100 (2012)
PM ID: 22955619
504: Lan X, Farnham PJ, Jin VX
Uncovering Transcription Factor Modules Using One- and Three-dimensional Analyses.
J Biol Chem 287: 30914-21 (2012)
PM ID: 22952238 PMC3438924
505: Frietze S, Wang R, Yao L, Tak YG, Ye Z, Gaddis M, Witt H, Farnham PJ, Jin VX
Cell type-specific binding patterns reveal that TCF7L2 can be tethered to the genome by association with GATA3.
Genome Biol 13: R52 (2012)
PM ID: 22951069
506: Kage H, Borok Z
EMT and interstitial lung disease: a mysterious relationship.
Curr Opin Pulm Med 18: 517-23 (2012)
PM ID: 22854509
507: Cox SG, Kim H, Garnett AT, Medeiros DM, An W, Crump JG
An essential role of variant histone H3.3 for ectomesenchyme potential of the cranial neural crest.
PLoS Genet 8: e1002938 (2012)
PM ID: 23028350 PMC3447937
508: Yashar P, Zada G, Harris B, Giannotta SL
Extent of resection and early postoperative outcomes following removal of cystic vestibular schwannomas: surgical experience over a decade and review of the literature.
Neurosurg Focus 33: E13 (2012)
PM ID: 22937847
509: Puri AS, Zada G, Zarzour H, Laws E, Frerichs K
Cerebral vasospasm after transsphenoidal resection of pituitary macroadenomas: report of 3 cases and review of the literature.
Neurosurgery 71: 173-80; discussion 180-1 (2012)
PM ID: 22249952
510: Lucas JW, Zada G
Imaging of the pituitary and parasellar region.
Semin Neurol 32: 320-31 (2012)
PM ID: 23361479
511: Coetzee SG, Rhie SK, Berman BP, Coetzee GA, Noushmehr H
FunciSNP: an R/bioconductor tool integrating functional non-coding data sets with genetic association studies to identify candidate regulatory SNPs.
Nucleic Acids Res 40: e139 (2012)
PM ID: 22684628 PMC3467035
512: Cortessis VK, Thomas DC, Levine AJ, Breton CV, Mack TM, Siegmund KD, Haile RW, Laird PW
Environmental epigenetics: prospects for studying epigenetic mediation of exposure-response relationships.
Hum Genet 131: 1565-89 (2012)
PM ID: 22740325 PMC3432200
513: Trotta AP, Need EF, Butler LM, Selth LA, O'Loughlin MA, Coetzee GA, Tilley WD, Buchanan G
Subdomain structure of the co-chaperone SGTA and activity of its androgen receptor client.
J Mol Endocrinol 49: 57-68 (2012)
PM ID: 22693264
514: Gundimeda U, McNeill TH, Elhiani AA, Schiffman JE, Hinton DR, Gopalakrishna R
Green tea polyphenols precondition against cell death induced by oxygen-glucose deprivation via stimulation of laminin receptor, generation of reactive oxygen species, and activation of protein kinase Cε.
J Biol Chem 287: 34694-708 (2012)
PM ID: 22879598 PMC3464573
515: Zhang S, Liu CC, Li W, Shen H, Laird PW, Zhou XJ
Discovery of multi-dimensional modules by integrative analysis of cancer genomic data.
Nucleic Acids Res 40: 9379-91 (2012)
PM ID: 22879375 PMC3479191
516: Tewari AK, Yardimci GG, Shibata Y, Sheffield NC, Song L, Taylor BS, Georgiev SG, Coetzee GA, Ohler U, Furey TS, Crawford GE, Febbo PG
Chromatin accessibility reveals insights into androgen receptor activation and transcriptional specificity.
Genome Biol 13: R88 (2012)
PM ID: 23034120
517: Pelikan RC, Iwata J, Suzuki A, Chai Y, Hacia JG
Identification of candidate downstream targets of TGFβ signaling during palate development by genome-wide transcript profiling.
J Cell Biochem : (2012)
PM ID: 23060211
518: Wang XM, Yik WY, Zhang P, Lu W, Dranchak PK, Shibata D, Steinberg SJ, Hacia JG
The gene expression profiles of induced pluripotent stem cells from individuals with childhood cerebral adrenoleukodystrophy are consistent with proposed mechanisms of pathogenesis.
Stem Cell Res Ther 3: 39 (2012)
PM ID: 23036268
519: Tiozzo C, Carraro G, Al Alam D, Baptista S, Danopoulos S, Li A, Lavarreda-Pearce M, Li C, De Langhe S, Chan B, Borok Z, Bellusci S, Minoo P
Mesodermal Pten inactivation leads to alveolar capillary dysplasia-like phenotype.
J Clin Invest : (2012)
PM ID: 23023706
520: Yan HX, Wu HP, Zhang HL, Ashton C, Tong C, Wu J, Qian QJ, Wang HY, Ying QL
DNA damage-induced sustained p53 activation contributes to inflammation-associated hepatocarcinogenesis in rats.
Oncogene : (2012)
PM ID: 23069657
521: Su SF, Chang YW, Andreu-Vieyra C, Fang JY, Yang Z, Han B, Lee AS, Liang G
miR-30d, miR-181a and miR-199a-5p cooperatively suppress the endoplasmic reticulum chaperone and signaling regulator GRP78 in cancer.
Oncogene : (2012)
PM ID: 23085757
522: Lucas JW, Zada G
Endoscopic surgery for pituitary tumors.
Neurosurg Clin N Am 23: 555-69 (2012)
PM ID: 23040743
523: Ishii M, Arias AC, Liu L, Chen YB, Bronner ME, Maxson RE
A stable cranial neural crest cell line from mouse.
Stem Cells Dev 21: 3069-80 (2012)
PM ID: 22889333 PMC3495126
524: Chen Y, Bates DL, Dey R, Chen PH, Machado AC, Laird-Offringa IA, Rohs R, Chen L
DNA binding by GATA transcription factor suggests mechanisms of DNA looping and long-range gene regulation.
Cell Rep 2: 1197-206 (2012)
PM ID: 23142663
525: Bittencourt D, Wu DY, Jeong KW, Gerke DS, Herviou L, Ianculescu I, Chodankar R, Siegmund KD, Stallcup MR
G9a functions as a molecular scaffold for assembly of transcriptional coactivators on a subset of glucocorticoid receptor target genes.
Proc Natl Acad Sci U S A 109: 19673-8 (2012)
PM ID: 23151507 PMC3511704
526: Nielsen CB, Younesy H, O'Geen H, Xu X, Jackson AR, Milosavljevic A, Wang T, Costello JF, Hirst M, Farnham PJ, Jones SJ
Spark: a navigational paradigm for genomic data exploration.
Genome Res 22: 2262-9 (2012)
PM ID: 22960372 PMC3483555
527: Khalessi AA, Zada G, Wang MY, Calland JF
Introduction: quality process improvement and the neurosurgeon.
Neurosurg Focus 33: Introduction (2012)
PM ID: 23116105
528: Pfaffenbach KT, Pong M, Morgan TE, Wang H, Ott K, Zhou B, Longo VD, Lee AS
GRP78/BiP is a novel downstream target of IGF-1 receptor mediated signaling.
J Cell Physiol 227: 3803-11 (2012)
PM ID: 22422508 PMC3421054 NIHMS364068
529: Li J, Jiang TX, Hughes MW, Wu P, Widelitz RB, Fan G, Chuong CM
Progressive alopecia reveals decreasing stem cell activation probability during aging of mice with epidermal deletion of DNA methyltransferase 1.
J Invest Dermatol 132: 2681-90 (2012)
PM ID: 22763785 PMC3465630 NIHMS378674
530: Yue Z, Jiang TX, Wu P, Widelitz RB, Chuong CM
Sprouty/FGF signaling regulates the proximal-distal feather morphology and the size of dermal papillae.
Dev Biol 372: 45-54 (2012)
PM ID: 23000358
531: Kelly TK, Liu Y, Lay FD, Liang G, Berman BP, Jones PA
Genome-wide mapping of nucleosome positioning and DNA methylation within individual DNA molecules.
Genome Res 22: 2497-506 (2012)
PM ID: 22960375 PMC3514679
532: Siddiq A, Couch FJ, Chen GK, Lindström S, Eccles D, Millikan RC, Michailidou K, Stram DO, Beckmann L, Rhie SK, Ambrosone CB, Aittomäki K, Amiano P, Apicella C, Australian Breast Cancer Tissue Bank Investigators , Baglietto L, Bandera EV, Beckmann MW, Berg CD, Bernstein L, Blomqvist C, Brauch H, Brinton L, Bui QM, Buring JE, Buys SS, Campa D, Carpenter JE, Chasman DI, Chang-Claude J, Chen C, Clavel-Chapelon F, Cox A, Cross SS, Czene K, Deming SL, Diasio RB, Diver WR, Dunning AM, Durcan L, Ekici AB, Fasching PA, Familial Breast Cancer Study , Feigelson HS, Fejerman L, Figueroa JD, Fletcher O, Flesch-Janys D, Gaudet MM, GENICA Consortium , Gerty SM, Rodriguez-Gil JL, Giles GG, van Gils CH, Godwin AK, Graham N, Greco D, Hall P, Hankinson SE, Hartmann A, Hein R, Heinz J, Hoover RN, Hopper JL, Hu JJ, Huntsman S, Ingles SA, Irwanto A, Isaacs C, Jacobs KB, John EM, Justenhoven C, Kaaks R, Kolonel LN, Coetzee GA, Lathrop M, Le Marchand L, Lee AM, Lee IM, Lesnick T, Lichtner P, Liu J, Lund E, Makalic E, Martin NG, McLean CA, Meijers-Heijboer H, Meindl A, Miron P, Monroe KR, Montgomery GW, Müller-Myhsok B, Nickels S, Nyante SJ, Olswold C, Overvad K, Palli D, Park DJ, Palmer JR, Pathak H, Peto J, Pharoah P, Rahman N, Rivadeneira F, Schmidt DF, Schmutzler RK, Slager S, Southey MC, Stevens KN, Sinn HP, Press MF, Ross E, Riboli E, Ridker PM, Schumacher FR, Severi G, Dos Santos Silva I, Stone J, Sund M, Tapper WJ, Thun MJ, Travis RC, Turnbull C, Uitterlinden AG, Waisfisz Q, Wang X, Wang Z, Weaver J, Schulz-Wendtland R, Wilkens LR, Van Den Berg D, Zheng W, Ziegler RG, Ziv E, Nevanlinna H, Easton DF, Hunter DJ, Henderson BE, Chanock SJ, Garcia-Closas M, Kraft P, Haiman CA, Vachon CM
A meta-analysis of genome-wide association studies of breast cancer identifies two novel susceptibility loci at 6q14 and 20q11.
Hum Mol Genet 21: 5373-84 (2012)
PM ID: 22976474 PMC3510753 [Available on 12/15/13]
533: Beck S, Bernstein BE, Campbell RM, Costello JF, Dhanak D, Ecker JR, Greally JM, Issa JP, Laird PW, Polyak K, Tycko B, Jones PA, AACR Cancer Epigenome Task Force
A blueprint for an international cancer epigenome consortium. A report from the AACR Cancer Epigenome Task Force.
Cancer Res 72: 6319-24 (2012)
PM ID: 23188507
534: Marotta NP, Cherwien CA, Abeywardana T, Pratt MR
O-GlcNAc modification prevents peptide-dependent acceleration of α-synuclein aggregation.
Chembiochem 13: 2665-70 (2012)
PM ID: 23143740
535: Bateman LA, Zaro BW, Chuh KN, Pratt MR
N-Propargyloxycarbamate monosaccharides as metabolic chemical reporters of carbohydrate salvage pathways and protein glycosylation.
Chem Commun (Camb) : (2012)
PM ID: 23235740
536: Han A, Bandyopadhyay B, Jayaprakash P, Lua I, Sahu D, Chen M, Woodley DT, Li W
The anti-motility signaling mechanism of TGFβ3 that controls cell traffic during skin wound healing.
Biol Open 1: 1169-77 (2012)
PM ID: 23259050 PMC3522877