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Publications for Norris Cancer Center Members in the Epigenetics and Regulation Program

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Total Number of Publications: 513
Inter Programmatic Publications: 175
Intra Programmatic Publications: 85

1: Tsou JA, Kazarian M, Patel A, Galler JS, Laird-Offringa IA, Carpenter CL, London SJ
Low level anti-Hu reactivity: A risk marker for small cell lung cancer?
Cancer Detect Prev 32: 292-9 (2009)
PM ID: 19070439 PMC2952929 NIHMS87928
2: Haiman CA, Garcia RR, Hsu C, Xia L, Ha H, Sheng X, Le Marchand L, Kolonel LN, Henderson BE, Stallcup MR, Greene GL, Press MF
Screening and association testing of common coding variation in steroid hormone receptor co-activator and co-repressor genes in relation to breast cancer risk: the Multiethnic Cohort.
BMC Cancer 9: 43 (2009)
PM ID: 19183483 PMC2637888
3: Plikus MV, Widelitz RB, Maxson R, Chuong CM
Analyses of regenerative wave patterns in adult hair follicle populations reveal macro-environmental regulation of stem cell activity.
Int J Dev Biol 53: 857-68 (2009)
PM ID: 19378257 PMC2759942 NIHMS131491
4: Campan M, Weisenberger DJ, Trinh B, Laird PW
MethyLight.
Methods Mol Biol 507: 325-37 (2009)
PM ID: 18987824
5: Noh T, Gabet Y, Cogan J, Shi Y, Tank A, Sasaki T, Criswell B, Dixon A, Lee C, Tam J, Kohler T, Segev E, Kockeritz L, Woodgett J, Müller R, Chai Y, Smith E, Bab I, Frenkel B
Lef1 haploinsufficient mice display a low turnover and low bone mass phenotype in a gender- and age-specific manner.
PLoS One 4: e5438 (2009)
PM ID: 19412553 PMC2673053
6: Zhou L, Yan C, Gieling RG, Kida Y, Garner W, Li W, Han YP
Tumor necrosis factor-alpha induced expression of matrix metalloproteinase-9 through p21-activated kinase-1.
BMC Immunol 10: 15 (2009)
PM ID: 19298660 PMC2669056
7: Toleno DM, Renaud G, Wolfsberg TG, Islam M, Wildman DE, Siegmund KD, Hacia JG
Development and evaluation of new mask protocols for gene expression profiling in humans and chimpanzees.
BMC Bioinformatics 10: 77 (2009)
PM ID: 19265541 PMC2660304
8: Ni M, Zhou H, Wey S, Baumeister P, Lee AS
Regulation of PERK signaling and leukemic cell survival by a novel cytosolic isoform of the UPR regulator GRP78/BiP.
PLoS One 4: e6868 (2009)
PM ID: 19718440 PMC2729930
9: Joo J, Christensen L, Warner K, States L, Kang HG, Vo K, Lawlor ER, May WA
GLI1 is a central mediator of EWS/FLI1 signaling in Ewing tumors.
PLoS One 4: e7608 (2009)
PM ID: 19859563 PMC2763206
10: Hinoue T, Weisenberger DJ, Pan F, Campan M, Kim M, Young J, Whitehall VL, Leggett BA, Laird PW
Analysis of the association between CIMP and BRAF in colorectal cancer by DNA methylation profiling.
PLoS One 4: e8357 (2009)
PM ID: 20027224 PMC2791229
11: Shtir C, Pique-Regi R, Siegmund K, Morrison J, Schumacher F, Marjoram P
Copy number variation in the Framingham Heart Study.
BMC Proc 3 Suppl 7: S133 (2009)
PM ID: 20018000 PMC2795907
12: Borok Z
Role for alpha3 integrin in EMT and pulmonary fibrosis.
J Clin Invest 119: 7-10 (2009)
PM ID: 19104143 PMC2613449
13: Youssef RF, Mitra AP, Bartsch G, Jones PA, Skinner DG, Cote RJ
Molecular targets and targeted therapies in bladder cancer management.
World J Urol 27: 9-20 (2009)
PM ID: 19039591
14: Chen JL, Lin HH, Kim KJ, Lin A, Ou JH, Ann DK
PKC delta signaling: a dual role in regulating hypoxic stress-induced autophagy and apoptosis.
Autophagy 5: 244-6 (2009)
PM ID: 19098423 PMC2743529 NIHMS123596
15: Saito Y, Friedman JM, Chihara Y, Egger G, Chuang JC, Liang G
Epigenetic therapy upregulates the tumor suppressor microRNA-126 and its host gene EGFL7 in human cancer cells.
Biochem Biophys Res Commun 379: 726-31 (2009)
PM ID: 19116145
16: Zhang Z, Lan Y, Chai Y, Jiang R
Antagonistic actions of Msx1 and Osr2 pattern mammalian teeth into a single row.
Science 323: 1232-4 (2009)
PM ID: 19251632 PMC2650836 NIHMS88200
17: Chuong CM, Widelitz RB
The river of stem cells.
Cell Stem Cell 4: 100-2 (2009)
PM ID: 19200797
18: Rountree CB, Ding W, He L, Stiles B
Expansion of CD133-expressing liver cancer stem cells in liver-specific phosphatase and tensin homolog deleted on chromosome 10-deleted mice.
Stem Cells 27: 290-9 (2009)
PM ID: 19008348 PMC2847372 NIHMS187510
19: Wong AK, Mei L, Soares MA, Schönmeyr BH, Mehrara BJ
Radioprotection of osteoblasts by a fractionated dose regimen and amifostine.
Plast Reconstr Surg 123: 104S-13S (2009)
PM ID: 19182669
20: Asahina K, Tsai SY, Li P, Ishii M, Maxson RE, Sucov HM, Tsukamoto H
Mesenchymal origin of hepatic stellate cells, submesothelial cells, and perivascular mesenchymal cells during mouse liver development.
Hepatology 49: 998-1011 (2009)
PM ID: 19085956 PMC2673117 NIHMS98872
21: Jariwala U, Cogan JP, Jia L, Frenkel B, Coetzee GA
Inhibition of AR-mediated transcription by binding of Oct1 to a motif enriched in AR-occupied regions.
Prostate 69: 392-400 (2009)
PM ID: 19058140 PMC2743387 NIHMS129716
22: Joshi AD, Corral R, Siegmund KD, Haile RW, Le Marchand L, Martínez ME, Ahnen DJ, Sandler RS, Lance P, Stern MC
Red meat and poultry intake, polymorphisms in the nucleotide excision repair and mismatch repair pathways and colorectal cancer risk.
Carcinogenesis 30: 472-9 (2009)
PM ID: 19029193 PMC2722151
23: Ting MC, Wu NL, Roybal PG, Sun J, Liu L, Yen Y, Maxson RE
EphA4 as an effector of Twist1 in the guidance of osteogenic precursor cells during calvarial bone growth and in craniosynostosis.
Development 136: 855-64 (2009)
PM ID: 19201948 PMC2685950 NIHMS131479
24: Friedman JM, Liang G, Liu CC, Wolff EM, Tsai YC, Ye W, Zhou X, Jones PA
The putative tumor suppressor microRNA-101 modulates the cancer epigenome by repressing the polycomb group protein EZH2.
Cancer Res 69: 2623-9 (2009)
PM ID: 19258506
25: Siegmund KD, Marjoram P, Woo YJ, Tavaré S, Shibata D
Inferring clonal expansion and cancer stem cell dynamics from DNA methylation patterns in colorectal cancers.
Proc Natl Acad Sci U S A 106: 4828-33 (2009)
PM ID: 19261858 PMC2651202
26: Woo YJ, Siegmund KD, Tavaré S, Shibata D
Older individuals appear to acquire mitotically older colorectal cancers.
J Pathol 217: 483-8 (2009)
PM ID: 19165870
27: Bapat B, Lindor NM, Baron J, Siegmund K, Li L, Zheng Y, Haile R, Gallinger S, Jass JR, Young JP, Cotterchio M, Jenkins M, Grove J, Casey G, Thibodeau SN, Bishop DT, Hopper JL, Ahnen D, Newcomb PA, Le Marchand L, Potter JD, Seminara D, Colon Cancer Family Registry
The association of tumor microsatellite instability phenotype with family history of colorectal cancer.
Cancer Epidemiol Biomarkers Prev 18: 967-75 (2009)
PM ID: 19258475 PMC2763617 NIHMS139549
28: Shi S, Chai Y, Slavkin H
Emerging opportunities for the next generation of dental implants?
Dent Today 28: 98-9 (2009)
PM ID: 19323323
29: Patel LN, Wang J, Kim KJ, Borok Z, Crandall ED, Shen WC
Conjugation with cationic cell-penetrating peptide increases pulmonary absorption of insulin.
Mol Pharm 6: 492-503 (2009)
PM ID: 19228019 PMC2798810 NIHMS96766
30: Lee YH, Stallcup MR
Minireview: protein arginine methylation of nonhistone proteins in transcriptional regulation.
Mol Endocrinol 23: 425-33 (2009)
PM ID: 19164444 PMC2667706
31: Aparicio A, North B, Barske L, Wang X, Bollati V, Weisenberger D, Yoo C, Tannir N, Horne E, Groshen S, Jones P, Yang A, Issa JP
LINE-1 methylation in plasma DNA as a biomarker of activity of DNA methylation inhibitors in patients with solid tumors.
Epigenetics 4: 176-84 (2009)
PM ID: 19421002 PMC2848123 NIHMS184539
32: Berman BP, Weisenberger DJ, Laird PW
Locking in on the human methylome.
Nat Biotechnol 27: 341-2 (2009)
PM ID: 19352369
33: Chung IH, Yamaza T, Zhao H, Choung PH, Shi S, Chai Y
Stem cell property of postmigratory cranial neural crest cells and their utility in alveolar bone regeneration and tooth development.
Stem Cells 27: 866-77 (2009)
PM ID: 19350689 PMC2896558 NIHMS214227
34: Stiles BL
Phosphatase and tensin homologue deleted on chromosome 10: extending its PTENtacles.
Int J Biochem Cell Biol 41: 757-61 (2009)
PM ID: 18950730 PMC2940266 NIHMS99348
35: Sohn KJ, Jang H, Campan M, Weisenberger DJ, Dickhout J, Wang YC, Cho RC, Yates Z, Lucock M, Chiang EP, Austin RC, Choi SW, Laird PW, Kim YI
The methylenetetrahydrofolate reductase C677T mutation induces cell-specific changes in genomic DNA methylation and uracil misincorporation: a possible molecular basis for the site-specific cancer risk modification.
Int J Cancer 124: 1999-2005 (2009)
PM ID: 19123462 PMC2692263 NIHMS99332
36: Kumar SR, Scehnet JS, Ley EJ, Singh J, Krasnoperov V, Liu R, Manchanda PK, Ladner RD, Hawes D, Weaver FA, Beart RW, Singh G, Nguyen C, Kahn M, Gill PS
Preferential induction of EphB4 over EphB2 and its implication in colorectal cancer progression.
Cancer Res 69: 3736-45 (2009)
PM ID: 19366806
37: Baumeister P, Dong D, Fu Y, Lee AS
Transcriptional induction of GRP78/BiP by histone deacetylase inhibitors and resistance to histone deacetylase inhibitor-induced apoptosis.
Mol Cancer Ther 8: 1086-94 (2009)
PM ID: 19417144 PMC2889001 NIHMS131011
38: Berman BP, Frenkel B, Coetzee GA
Location, location, (ChIP-)location! Mapping chromatin landscapes one immunoprecipitation at a time.
J Cell Biochem 107: 1-5 (2009)
PM ID: 19308935 PMC2748114 NIHMS136755
39: Woodley DT, Fan J, Cheng CF, Li Y, Chen M, Bu G, Li W
Participation of the lipoprotein receptor LRP1 in hypoxia-HSP90alpha autocrine signaling to promote keratinocyte migration.
J Cell Sci 122: 1495-8 (2009)
PM ID: 19383717 PMC2680098
40: Lyu J, Wesselschmidt RL, Lu W
Cdc37 regulates Ryk signaling by stabilizing the cleaved Ryk intracellular domain.
J Biol Chem 284: 12940-8 (2009)
PM ID: 19269974 PMC2676025
41: Miranda TB, Cortez CC, Yoo CB, Liang G, Abe M, Kelly TK, Marquez VE, Jones PA
DZNep is a global histone methylation inhibitor that reactivates developmental genes not silenced by DNA methylation.
Mol Cancer Ther 8: 1579-88 (2009)
PM ID: 19509260 PMC3186068 NIHMS325029
42: Demaio L, Tseng W, Balverde Z, Alvarez JR, Kim KJ, Kelley DG, Senior RM, Crandall ED, Borok Z
Characterization of mouse alveolar epithelial cell monolayers.
Am J Physiol Lung Cell Mol Physiol 296: L1051-8 (2009)
PM ID: 19329539 PMC2692796
43: Ou CY, Kim JH, Yang CK, Stallcup MR
Requirement of cell cycle and apoptosis regulator 1 for target gene activation by Wnt and beta-catenin and for anchorage-independent growth of human colon carcinoma cells.
J Biol Chem 284: 20629-37 (2009)
PM ID: 19520846 PMC2742827
44: Siegmund KD, Marjoram P, Tavaré S, Shibata D
Many colorectal cancers are "flat" clonal expansions.
Cell Cycle 8: 2187-93 (2009)
PM ID: 19556889
45: Rosol M, Harutyunyan I, Xu J, Melendez E, Smbatyan G, Finlay JL, Krieger MD, Gonzalez-Gomez I, Reynolds CP, Nelson MD, Erdreich-Epstein A, Blüml S
Metabolism of orthotopic mouse brain tumor models.
Mol Imaging 8: 199-208 (2009)
PM ID: 19728974
46: Butturini AM, Jacob M, Aguajo J, Vander-Walde NA, Villablanca J, Jubran R, Erdreich-Epstein A, Marachelian A, Dhall G, Finlay JL
High-dose chemotherapy and autologous hematopoietic progenitor cell rescue in children with recurrent medulloblastoma and supratentorial primitive neuroectodermal tumors: the impact of prior radiotherapy on outcome.
Cancer 115: 2956-63 (2009)
PM ID: 19402050
47: Li AY, Boo LM, Wang SY, Lin HH, Wang CC, Yen Y, Chen BP, Chen DJ, Ann DK
Suppression of nonhomologous end joining repair by overexpression of HMGA2.
Cancer Res 69: 5699-706 (2009)
PM ID: 19549901 PMC2737594 NIHMS119606
48: Kim H, Heo K, Kim JH, Kim K, Choi J, An W
Requirement of histone methyltransferase SMYD3 for estrogen receptor-mediated transcription.
J Biol Chem 284: 19867-77 (2009)
PM ID: 19509295 PMC2740412
49: Baniwal SK, Khalid O, Sir D, Buchanan G, Coetzee GA, Frenkel B
Repression of Runx2 by androgen receptor (AR) in osteoblasts and prostate cancer cells: AR binds Runx2 and abrogates its recruitment to DNA.
Mol Endocrinol 23: 1203-14 (2009)
PM ID: 19389811 PMC2718746
50: Pomerantz MM, Ahmadiyeh N, Jia L, Herman P, Verzi MP, Doddapaneni H, Beckwith CA, Chan JA, Hills A, Davis M, Yao K, Kehoe SM, Lenz HJ, Haiman CA, Yan C, Henderson BE, Frenkel B, Barretina J, Bass A, Tabernero J, Baselga J, Regan MM, Manak JR, Shivdasani R, Coetzee GA, Freedman ML
The 8q24 cancer risk variant rs6983267 shows long-range interaction with MYC in colorectal cancer.
Nat Genet 41: 882-4 (2009)
PM ID: 19561607 PMC2763485 NIHMS120360
51: Guan S, Fan J, Han A, Chen M, Woodley DT, Li W
Non-compensating roles between Nckalpha and Nckbeta in PDGF-BB signaling to promote human dermal fibroblast migration.
J Invest Dermatol 129: 1909-20 (2009)
PM ID: 19242519
52: Choi SH, Worswick S, Byun HM, Shear T, Soussa JC, Wolff EM, Douer D, Garcia-Manero G, Liang G, Yang AS
Changes in DNA methylation of tandem DNA repeats are different from interspersed repeats in cancer.
Int J Cancer 125: 723-9 (2009)
PM ID: 19437537 PMC4086885 NIHMS587075
53: Friedman JM, Jones PA
MicroRNAs: critical mediators of differentiation, development and disease.
Swiss Med Wkly 139: 466-72 (2009)
PM ID: 19705306 PMC2854010 NIHMS185177
54: Friedman JM, Jones PA, Liang G
The tumor suppressor microRNA-101 becomes an epigenetic player by targeting the polycomb group protein EZH2 in cancer.
Cell Cycle 8: 2313-4 (2009)
PM ID: 19625769 PMC2846299 NIHMS185710
55: Jia L, Landan G, Pomerantz M, Jaschek R, Herman P, Reich D, Yan C, Khalid O, Kantoff P, Oh W, Manak JR, Berman BP, Henderson BE, Frenkel B, Haiman CA, Freedman M, Tanay A, Coetzee GA
Functional enhancers at the gene-poor 8q24 cancer-linked locus.
PLoS Genet 5: e1000597 (2009)
PM ID: 19680443 PMC2717370
56: Peters AA, Buchanan G, Ricciardelli C, Bianco-Miotto T, Centenera MM, Harris JM, Jindal S, Segara D, Jia L, Moore NL, Henshall SM, Birrell SN, Coetzee GA, Sutherland RL, Butler LM, Tilley WD
Androgen receptor inhibits estrogen receptor-alpha activity and is prognostic in breast cancer.
Cancer Res 69: 6131-40 (2009)
PM ID: 19638585
57: Li F, Zeng B, Chai Y, Cai P, Fan C, Cheng T
The linker region of Smad2 mediates TGF-beta-dependent ERK2-induced collagen synthesis.
Biochem Biophys Res Commun 386: 289-93 (2009)
PM ID: 19465000
58: Zhong S, Johnson DL
The JNKs differentially regulate RNA polymerase III transcription by coordinately modulating the expression of all TFIIIB subunits.
Proc Natl Acad Sci U S A 106: 12682-7 (2009)
PM ID: 19620725 PMC2722300
59: Jiang X, Gwye Y, McKeown SJ, Bronner-Fraser M, Lutzko C, Lawlor ER
Isolation and characterization of neural crest stem cells derived from in vitro-differentiated human embryonic stem cells.
Stem Cells Dev 18: 1059-70 (2009)
PM ID: 19099373
60: Wang M, Wey S, Zhang Y, Ye R, Lee AS
Role of the unfolded protein response regulator GRP78/BiP in development, cancer, and neurological disorders.
Antioxid Redox Signal 11: 2307-16 (2009)
PM ID: 19309259 PMC2819800
61: Bouazoune K, Miranda TB, Jones PA, Kingston RE
Analysis of individual remodeled nucleosomes reveals decreased histone-DNA contacts created by hSWI/SNF.
Nucleic Acids Res 37: 5279-94 (2009)
PM ID: 19567737 PMC2760786
62: Spektor TM, Rice JC
Identification and characterization of posttranslational modification-specific binding proteins in vivo by mammalian tethered catalysis.
Proc Natl Acad Sci U S A 106: 14808-13 (2009)
PM ID: 19706462 PMC2736425
63: Dieli-Conwright CM, Spektor TM, Rice JC, Sattler FR, Schroeder ET
Hormone therapy attenuates exercise-induced skeletal muscle damage in postmenopausal women.
J Appl Physiol (1985) 107: 853-8 (2009)
PM ID: 19574506
64: Willis BC, Borok Z
Epithelial-mesenchymal transition: potential role in obliterative bronchiolitis?
Thorax 64: 742-3 (2009)
PM ID: 19717708
65: Gundimeda U, Schiffman JE, Gottlieb SN, Roth BI, Gopalakrishna R
Negation of the cancer-preventive actions of selenium by over-expression of protein kinase Cepsilon and selenoprotein thioredoxin reductase.
Carcinogenesis 30: 1553-61 (2009)
PM ID: 19578042
66: Jeong KW, Lee YH, Stallcup MR
Recruitment of the SWI/SNF chromatin remodeling complex to steroid hormone-regulated promoters by nuclear receptor coactivator flightless-I.
J Biol Chem 284: 29298-309 (2009)
PM ID: 19720835 PMC2785560
67: Jeong S, Liang G, Sharma S, Lin JC, Choi SH, Han H, Yoo CB, Egger G, Yang AS, Jones PA
Selective anchoring of DNA methyltransferases 3A and 3B to nucleosomes containing methylated DNA.
Mol Cell Biol 29: 5366-76 (2009)
PM ID: 19620278 PMC2747980
68: Poynter JN, Haile RW, Siegmund KD, Campbell PT, Figueiredo JC, Limburg P, Young J, Le Marchand L, Potter JD, Cotterchio M, Casey G, Hopper JL, Jenkins MA, Thibodeau SN, Newcomb PA, Baron JA, Colon Cancer Family Registry
Associations between smoking, alcohol consumption, and colorectal cancer, overall and by tumor microsatellite instability status.
Cancer Epidemiol Biomarkers Prev 18: 2745-50 (2009)
PM ID: 19755657 PMC2759847 NIHMS140217
69: Huang X, Bringas P, Slavkin HC, Chai Y
Fate of HERS during tooth root development.
Dev Biol 334: 22-30 (2009)
PM ID: 19576204 PMC2744848 NIHMS139234
70: Lin CM, Jiang TX, Baker RE, Maini PK, Widelitz RB, Chuong CM
Spots and stripes: pleomorphic patterning of stem cells via p-ERK-dependent cell chemotaxis shown by feather morphogenesis and mathematical simulation.
Dev Biol 334: 369-82 (2009)
PM ID: 19647731 PMC2811698 NIHMS145522
71: Choi J, Heo K, An W
Cooperative action of TIP48 and TIP49 in H2A.Z exchange catalyzed by acetylation of nucleosomal H2A.
Nucleic Acids Res 37: 5993-6007 (2009)
PM ID: 19696079 PMC2764430
72: Tiozzo C, De Langhe S, Yu M, Londhe VA, Carraro G, Li M, Li C, Xing Y, Anderson S, Borok Z, Bellusci S, Minoo P
Deletion of Pten expands lung epithelial progenitor pools and confers resistance to airway injury.
Am J Respir Crit Care Med 180: 701-12 (2009)
PM ID: 19574443 PMC2778148
73: Jones PA, Liang G
Rethinking how DNA methylation patterns are maintained.
Nat Rev Genet 10: 805-11 (2009)
PM ID: 19789556 PMC2848124 [Available on 11/01/10] NIHMS185221 [Available on 11/01/10]
74: Dieli-Conwright CM, Spektor TM, Rice JC, Sattler FR, Schroeder ET
Influence of hormone replacement therapy on eccentric exercise induced myogenic gene expression in postmenopausal women.
J Appl Physiol (1985) 107: 1381-8 (2009)
PM ID: 19696363 PMC2777804
75: Dieli-Conwright CM, Spektor TM, Rice JC, Todd Schroeder E
Oestradiol and SERM treatments influence oestrogen receptor coregulator gene expression in human skeletal muscle cells.
Acta Physiol (Oxf) 197: 187-96 (2009)
PM ID: 19432593
76: Felton VM, Borok Z, Willis BC
N-acetylcysteine inhibits alveolar epithelial-mesenchymal transition.
Am J Physiol Lung Cell Mol Physiol 297: L805-12 (2009)
PM ID: 19648289 PMC2777496
77: Stiles BL
PI-3-K and AKT: Onto the mitochondria.
Adv Drug Deliv Rev 61: 1276-82 (2009)
PM ID: 19720099
78: Hu K, Lee C, Qiu D, Fotovati A, Davies A, Abu-Ali S, Wai D, Lawlor ER, Triche TJ, Pallen CJ, Dunn SE
Small interfering RNA library screen of human kinases and phosphatases identifies polo-like kinase 1 as a promising new target for the treatment of pediatric rhabdomyosarcomas.
Mol Cancer Ther 8: 3024-35 (2009)
PM ID: 19887553 PMC2783569 NIHMS150149
79: Lee AS
The Par-4-GRP78 TRAIL, more twists and turns.
Cancer Biol Ther 8: 2103-5 (2009)
PM ID: 19823030 PMC2849277 NIHMS188340
80: Byun HM, Siegmund KD, Pan F, Weisenberger DJ, Kanel G, Laird PW, Yang AS
Epigenetic profiling of somatic tissues from human autopsy specimens identifies tissue- and individual-specific DNA methylation patterns.
Hum Mol Genet 18: 4808-17 (2009)
PM ID: 19776032
81: Kazarian M, Calbo J, Proost N, Carpenter CL, Berns A, Laird-Offringa IA
Immune response in lung cancer mouse model mimics human anti-Hu reactivity.
J Neuroimmunol 217: 38-45 (2009)
PM ID: 19765830 PMC2788043 NIHMS144833
82: Borok Z, Crandall ED
More life for a "terminal" cell.
Am J Physiol Lung Cell Mol Physiol 297: L1042-4 (2009)
PM ID: 19837848 PMC2793181
83: Wei Z, Yang Y, Zhang P, Andrianakos R, Hasegawa K, Lyu J, Chen X, Bai G, Liu C, Pera M, Lu W
Klf4 interacts directly with Oct4 and Sox2 to promote reprogramming.
Stem Cells 27: 2969-78 (2009)
PM ID: 19816951
84: Ricca TI, Liang G, Suenaga AP, Han SW, Jones PA, Jasiulionis MG
Tissue inhibitor of metalloproteinase 1 expression associated with gene demethylation confers anoikis resistance in early phases of melanocyte malignant transformation.
Transl Oncol 2: 329-40 (2009)
PM ID: 19956395 PMC2781071
85: Mao C, Wang M, Luo B, Wey S, Dong D, Wesselschmidt R, Rawlings S, Lee AS
Targeted mutation of the mouse Grp94 gene disrupts development and perturbs endoplasmic reticulum stress signaling.
PLoS One 5: e10852 (2010)
PM ID: 20520781 PMC2877114
86: Jiang X, Gwye Y, Russell D, Cao C, Douglas D, Hung L, Kovar H, Triche TJ, Lawlor ER
CD133 expression in chemo-resistant Ewing sarcoma cells.
BMC Cancer 10: 116 (2010)
PM ID: 20346143 PMC2851692
87: Qiu X, Hother C, Ralfkiær UM, Søgaard A, Lu Q, Workman CT, Liang G, Jones PA, Grønbaek K
Equitoxic doses of 5-azacytidine and 5-aza-2'deoxycytidine induce diverse immediate and overlapping heritable changes in the transcriptome.
PLoS One 5: (2010)
PM ID: 20927380 PMC2947512
88: Hong YJ, Marjoram P, Shibata D, Siegmund KD
Using DNA methylation patterns to infer tumor ancestry.
PLoS One 5: e12002 (2010)
PM ID: 20711251 PMC2918495
89: Baniwal SK, Khalid O, Gabet Y, Shah RR, Purcell DJ, Mav D, Kohn-Gabet AE, Shi Y, Coetzee GA, Frenkel B
Runx2 transcriptome of prostate cancer cells: insights into invasiveness and bone metastasis.
Mol Cancer 9: 258 (2010)
PM ID: 20863401 PMC2955618
90: Watkins PA, Moser AB, Toomer CB, Steinberg SJ, Moser HW, Karaman MW, Ramaswamy K, Siegmund KD, Lee DR, Ely JJ, Ryder OA, Hacia JG
Identification of differences in human and great ape phytanic acid metabolism that could influence gene expression profiles and physiological functions.
BMC Physiol 10: 19 (2010)
PM ID: 20932325 PMC2964658
91: Zeng N, Bayan JA, He L, Stiles B
The Role of PTEN in β-Cell Growth.
Open Endocrinol J 4: 23-32 (2010)
PM ID: 23853672 PMC3708799 NIHMS419651
92: Ye R, Jung DY, Jun JY, Li J, Luo S, Ko HJ, Kim JK, Lee AS
Grp78 heterozygosity promotes adaptive unfolded protein response and attenuates diet-induced obesity and insulin resistance.
Diabetes 59: 6-16 (2010)
PM ID: 19808896 PMC2797945
93: Sharma S, Kelly TK, Jones PA
Epigenetics in cancer.
Carcinogenesis 31: 27-36 (2010)
PM ID: 19752007 PMC2802667
94: Zhong JF, Weiner L, Jin Y, Lu W, Taylor CR
A real-time pluripotency reporter for human stem cells.
Stem Cells Dev 19: 47-52 (2010)
PM ID: 19473101
95: Miranda TB, Kelly TK, Bouazoune K, Jones PA
Methylation-sensitive single-molecule analysis of chromatin structure.
Curr Protoc Mol Biol Chapter 21: Unit 21.17.1-16 (2010)
PM ID: 20069538
96: Coetzee GA, Jia L, Frenkel B, Henderson BE, Tanay A, Haiman CA, Freedman ML
A systematic approach to understand the functional consequences of non-protein coding risk regions.
Cell Cycle 9: 256-9 (2010)
PM ID: 20023379 PMC3319348 NIHMS231263
97: Hong H, Yen HY, Brockmeyer A, Liu Y, Chodankar R, Pike MC, Stanczyk FZ, Maxson R, Dubeau L
Changes in the mouse estrus cycle in response to BRCA1 inactivation suggest a potential link between risk factors for familial and sporadic ovarian cancer.
Cancer Res 70: 221-8 (2010)
PM ID: 20028858 PMC2805040 NIHMS157376
98: Song HR, Gonzalez-Gomez I, Suh GS, Commins DL, Sposto R, Gilles FH, Deneen B, Erdreich-Epstein A
Nuclear factor IA is expressed in astrocytomas and is associated with improved survival.
Neuro Oncol 12: 122-32 (2010)
PM ID: 20150379 PMC2940580
99: Iwata J, Hosokawa R, Sanchez-Lara PA, Urata M, Slavkin H, Chai Y
Transforming growth factor-beta regulates basal transcriptional regulatory machinery to control cell proliferation and differentiation in cranial neural crest-derived osteoprogenitor cells.
J Biol Chem 285: 4975-82 (2010)
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100: Wang M, Ye R, Barron E, Baumeister P, Mao C, Luo S, Fu Y, Luo B, Dubeau L, Hinton DR, Lee AS
Essential role of the unfolded protein response regulator GRP78/BiP in protection from neuronal apoptosis.
Cell Death Differ 17: 488-98 (2010)
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101: Wang XM, Greiner TC, Bibikova M, Pike BL, Siegmund KD, Sinha UK, Müschen M, Jaeger EB, Weisenburger DD, Chan WC, Shibata D, Fan JB, Hacia JG
Identification and functional relevance of de novo DNA methylation in cancerous B-cell populations.
J Cell Biochem 109: 818-27 (2010)
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102: Sir D, Tian Y, Chen WL, Ann DK, Yen TS, Ou JH
The early autophagic pathway is activated by hepatitis B virus and required for viral DNA replication.
Proc Natl Acad Sci U S A 107: 4383-8 (2010)
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Kruppel-like factor 4 (Klf4) prevents embryonic stem (ES) cell differentiation by regulating Nanog gene expression.
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c-Abl mediates endothelial apoptosis induced by inhibition of integrins alphavbeta3 and alphavbeta5 and by disruption of actin.
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Current treatment protocols have eliminated the prognostic advantage of type 1 fusions in Ewing sarcoma: a report from the Children's Oncology Group.
J Clin Oncol 28: 1989-94 (2010)
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Age-dependent DNA methylation of genes that are suppressed in stem cells is a hallmark of cancer.
Genome Res 20: 440-6 (2010)
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A histone methylation code for SV40 minichromosomes.
Cell Cycle 9: 1235-6 (2010)
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Mechanisms of alveolar epithelial translocation of a defined population of nanoparticles.
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HuR/methyl-HuR and AUF1 regulate the MAT expressed during liver proliferation, differentiation, and carcinogenesis.
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Smad4-Shh-Nfic signaling cascade-mediated epithelial-mesenchymal interaction is crucial in regulating tooth root development.
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Mol Cancer Ther 9: 1443-50 (2010)
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Autophagy by hepatitis B virus and for hepatitis B virus.
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Proc Natl Acad Sci U S A 107: 9742-6 (2010)
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The critical role of AKT2 in hepatic steatosis induced by PTEN loss.
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Novel cancer vaccine based on genes of Salmonella pathogenicity island 2.
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Hormone therapy, DNA methylation and colon cancer.
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A chloroacetamidine-based inactivator of protein arginine methyltransferase 1: design, synthesis, and in vitro and in vivo evaluation.
Chembiochem 11: 1219-23 (2010)
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The endothelial cell receptor GRP78 is required for mucormycosis pathogenesis in diabetic mice.
J Clin Invest 120: 1914-24 (2010)
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Androgen receptor responsive enhancers are flanked by consistently-positioned H3-acetylated nucleosomes.
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Inactivation of Msx1 and Msx2 in neural crest reveals an unexpected role in suppressing heterotopic bone formation in the head.
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Cigarette smoking and colorectal cancer risk by molecularly defined subtypes.
J Natl Cancer Inst 102: 1012-22 (2010)
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H2A.Z maintenance during mitosis reveals nucleosome shifting on mitotically silenced genes.
Mol Cell 39: 901-11 (2010)
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Role for the nuclear receptor-binding SET domain protein 1 (NSD1) methyltransferase in coordinating lysine 36 methylation at histone 3 with RNA polymerase II function.
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The Wnt signaling pathway in cellular proliferation and differentiation: A tale of two coactivators.
Adv Drug Deliv Rev 62: 1149-55 (2010)
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Nat Biotechnol 28: 1069-1078 (2010)
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Unique DNA methylation patterns distinguish noninvasive and invasive urothelial cancers and establish an epigenetic field defect in premalignant tissue.
Cancer Res 70: 8169-78 (2010)
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Trends Cell Biol 20: 609-17 (2010)
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Vitamin C promotes widespread yet specific DNA demethylation of the epigenome in human embryonic stem cells.
Stem Cells 28: 1848-55 (2010)
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Human gingiva-derived mesenchymal stem cells elicit polarization of m2 macrophages and enhance cutaneous wound healing.
Stem Cells 28: 1856-68 (2010)
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Jagged1 functions downstream of Twist1 in the specification of the coronal suture and the formation of a boundary between osteogenic and non-osteogenic cells.
Dev Biol 347: 258-70 (2010)
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Targeting DNA methylation for epigenetic therapy.
Trends Pharmacol Sci 31: 536-46 (2010)
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Hypertension, diuretics and antihypertensives in relation to bladder cancer.
Carcinogenesis 31: 1964-71 (2010)
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Grp78 heterozygosity regulates chaperone balance in exocrine pancreas with differential response to cerulein-induced acute pancreatitis.
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Green tea polyphenols potentiate the action of nerve growth factor to induce neuritogenesis: possible role of reactive oxygen species.
J Neurosci Res 88: 3644-55 (2010)
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Polymorphisms in base excision repair genes as colorectal cancer risk factors and modifiers of the effect of diets high in red meat.
Cancer Epidemiol Biomarkers Prev 19: 3167-73 (2010)
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Liver-specific deletion of prohibitin 1 results in spontaneous liver injury, fibrosis, and hepatocellular carcinoma in mice.
Hepatology 52: 2096-108 (2010)
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Expansion of hepatic tumor progenitor cells in Pten-null mice requires liver injury and is reversed by loss of AKT2.
Gastroenterology 139: 2170-82 (2010)
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Measurement and modification of the expression level of the chaperone protein and signaling regulator GRP78/BiP in mammalian cells.
Methods Enzymol 490: 217-33 (2011)
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Nucleosomes containing methylated DNA stabilize DNA methyltransferases 3A/3B and ensure faithful epigenetic inheritance.
PLoS Genet 7: e1001286 (2011)
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Prog Drug Res 67: 1-23 (2011)
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TPL2/COT/MAP3K8 (TPL2) activation promotes androgen depletion-independent (ADI) prostate cancer growth.
PLoS One 6: e16205 (2011)
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156: Kazarian M, Laird-Offringa IA
Small-cell lung cancer-associated autoantibodies: potential applications to cancer diagnosis, early detection, and therapy.
Mol Cancer 10: 33 (2011)
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Human and great ape red blood cells differ in plasmalogen levels and composition.
Lipids Health Dis 10: 101 (2011)
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High DNA methylation pattern intratumoral diversity implies weak selection in many human colorectal cancers.
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PLoS One 6: e21443 (2011)
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The endoplasmic reticulum chaperone protein GRP94 is required for maintaining hematopoietic stem cell interactions with the adult bone marrow niche.
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Epigenetic subgroups of esophageal and gastric adenocarcinoma with differential GATA5 DNA methylation associated with clinical and lifestyle factors.
PLoS One 6: e25985 (2011)
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Modeling measurement error in tumor characterization studies.
BMC Bioinformatics 12: 284 (2011)
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Translocation of PEGylated quantum dots across rat alveolar epithelial cell monolayers.
Int J Nanomedicine 6: 2849-57 (2011)
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Genome-scale screen for DNA methylation-based detection markers for ovarian cancer.
PLoS One 6: e28141 (2011)
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Regulation of breast cancer metastasis by Runx2 and estrogen signaling: the role of SNAI2.
Breast Cancer Res 13: R127 (2011)
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Epigenetic modulation of miR-122 facilitates human embryonic stem cell self-renewal and hepatocellular carcinoma proliferation.
PLoS One 6: e27740 (2011)
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Gliovascular and cytokine interactions modulate brain endothelial barrier in vitro.
J Neuroinflammation 8: 162 (2011)
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Characterization of the contradictory chromatin signatures at the 3' exons of zinc finger genes.
PLoS One 6: e17121 (2011)
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Using ChIP-seq technology to generate high-resolution profiles of histone modifications.
Methods Mol Biol 791: 265-86 (2011)
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171: Cooper A, van Doorninck J, Ji L, Russell D, Ladanyi M, Shimada H, Krailo M, Womer RB, Hsu JH, Thomas D, Triche TJ, Sposto R, Lawlor ER
Ewing tumors that do not overexpress BMI-1 are a distinct molecular subclass with variant biology: a report from the Children's Oncology Group.
Clin Cancer Res 17: 56-66 (2011)
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A let-7 microRNA-binding site polymorphism in 3'-untranslated region of KRAS gene predicts response in wild-type KRAS patients with metastatic colorectal cancer treated with cetuximab monotherapy.
Ann Oncol 22: 104-9 (2011)
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173: Zhong S, Machida K, Tsukamoto H, Johnson DL
Alcohol induces RNA polymerase III-dependent transcription through c-Jun by co-regulating TATA-binding protein (TBP) and Brf1 expression.
J Biol Chem 286: 2393-401 (2011)
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TbetaRI/Alk5-independent TbetaRII signaling to ERK1/2 in human skin cells according to distinct levels of TbetaRII expression.
J Cell Sci 124: 19-24 (2011)
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175: Kastrinos F, Steyerberg EW, Mercado R, Balmaña J, Holter S, Gallinger S, Siegmund KD, Church JM, Jenkins MA, Lindor NM, Thibodeau SN, Burbidge LA, Wenstrup RJ, Syngal S
The PREMM(1,2,6) model predicts risk of MLH1, MSH2, and MSH6 germline mutations based on cancer history.
Gastroenterology 140: 73-81 (2011)
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Inhibition of joint damage and improved clinical outcomes with rituximab plus methotrexate in early active rheumatoid arthritis: the IMAGE trial.
Ann Rheum Dis 70: 39-46 (2011)
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Frequency of deletions of EPCAM (TACSTD1) in MSH2-associated Lynch syndrome cases.
J Mol Diagn 13: 93-9 (2011)
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Regulated recruitment of tumor suppressor BRCA1 to the p21 gene by coactivator methylation.
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Epithelium-specific deletion of TGF-β receptor type II protects mice from bleomycin-induced pulmonary fibrosis.
J Clin Invest 121: 277-87 (2011)
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Identification of preferential target sites for human DNA methyltransferases.
Nucleic Acids Res 39: 104-18 (2011)
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181: Iqbal S, Tsao-Wei DD, Quinn DI, Gitlitz BJ, Groshen S, Aparicio A, Lenz HJ, El-Khoueiry A, Pinski J, Garcia AA
Phase I clinical trial of pegylated liposomal Doxorubicin and docetaxel in patients with advanced solid tumors.
Am J Clin Oncol 34: 27-31 (2011)
PM ID: 20142723
182: Lee E, Nichols P, Groshen S, Spicer D, Lee AS
GRP78 as potential predictor for breast cancer response to adjuvant taxane therapy.
Int J Cancer 128: 726-31 (2011)
PM ID: 20473863 PMC2972376 NIHMS216547
183: Kelly TK, Jones PA
Role of nucleosomes in mitotic bookmarking.
Cell Cycle 10: 370-1 (2011)
PM ID: 21270523
184: Ouyang YB, Xu LJ, Emery JF, Lee AS, Giffard RG
Overexpressing GRP78 influences Ca2+ handling and function of mitochondria in astrocytes after ischemia-like stress.
Mitochondrion 11: 279-86 (2011)
PM ID: 21047562 PMC3037025 NIHMS254326
185: Ni M, Zhang Y, Lee AS
Beyond the endoplasmic reticulum: atypical GRP78 in cell viability, signalling and therapeutic targeting.
Biochem J 434: 181-8 (2011)
PM ID: 21309747 PMC3353658 NIHMS373948
186: Pfaffenbach KT, Lee AS
The critical role of GRP78 in physiologic and pathologic stress.
Curr Opin Cell Biol 23: 150-6 (2011)
PM ID: 20970977 PMC3043145 NIHMS247888
187: Yamada R, Cao X, Butkevich AN, Millard M, Odde S, Mordwinkin N, Gundla R, Zandi E, Louie SG, Petasis NA, Neamati N
Discovery and preclinical evaluation of a novel class of cytotoxic propynoic acid carbamoyl methyl amides (PACMAs).
J Med Chem 54: 2902-14 (2011)
PM ID: 21443194
188: Hughes MW, Wu P, Jiang TX, Lin SJ, Dong CY, Li A, Hsieh FJ, Widelitz RB, Chuong CM
In search of the Golden Fleece: unraveling principles of morphogenesis by studying the integrative biology of skin appendages.
Integr Biol (Camb) 3: 388-407 (2011)
PM ID: 21437328 PMC3620034 NIHMS397283
189: Molognoni F, Cruz AT, Meliso FM, Morais AS, Souza CF, Xander P, Bischof JM, Costa FF, Soares MB, Liang G, Jones PA, Jasiulionis MG
Epigenetic reprogramming as a key contributor to melanocyte malignant transformation.
Epigenetics 6: 450-64 (2011)
PM ID: 21343701 PMC3359486
190: Dong D, Stapleton C, Luo B, Xiong S, Ye W, Zhang Y, Jhaveri N, Zhu G, Ye R, Liu Z, Bruhn KW, Craft N, Groshen S, Hofman FM, Lee AS
A critical role for GRP78/BiP in the tumor microenvironment for neovascularization during tumor growth and metastasis.
Cancer Res 71: 2848-57 (2011)
PM ID: 21467168 PMC3078191 NIHMS276417
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A user's guide to the encyclopedia of DNA elements (ENCODE).
PLoS Biol 9: e1001046 (2011)
PM ID: 21526222 PMC3079585
192: Cao AR, Rabinovich R, Xu M, Xu X, Jin VX, Farnham PJ
Genome-wide analysis of transcription factor E2F1 mutant proteins reveals that N- and C-terminal protein interaction domains do not participate in targeting E2F1 to the human genome.
J Biol Chem 286: 11985-96 (2011)
PM ID: 21310950 PMC3069401
193: Zhao H, Li S, Han D, Kaartinen V, Chai Y
Alk5-mediated transforming growth factor β signaling acts upstream of fibroblast growth factor 10 to regulate the proliferation and maintenance of dental epithelial stem cells.
Mol Cell Biol 31: 2079-89 (2011)
PM ID: 21402782 PMC3133354
194: Ou CY, LaBonte MJ, Manegold PC, So AY, Ianculescu I, Gerke DS, Yamamoto KR, Ladner RD, Kahn M, Kim JH, Stallcup MR
A coactivator role of CARM1 in the dysregulation of β-catenin activity in colorectal cancer cell growth and gene expression.
Mol Cancer Res 9: 660-70 (2011)
PM ID: 21478268 PMC3096696 NIHMS284281
195: Lee YH, Stallcup MR
Roles of protein arginine methylation in DNA damage signaling pathways is CARM1 a life-or-death decision point?
Cell Cycle 10: 1343-4 (2011)
PM ID: 21445011 PMC3117038
196: Hung Y, Huang X, Chai Y
Molecular regulatory mechanism of root development.
J Calif Dent Assoc 39: 321-4 (2011)
PM ID: 21721476
197: Li J, Huang X, Xu X, Mayo J, Bringas P, Jiang R, Wang S, Chai Y
SMAD4-mediated WNT signaling controls the fate of cranial neural crest cells during tooth morphogenesis.
Development 138: 1977-89 (2011)
PM ID: 21490069 PMC3082303
198: Zaro BW, Yang YY, Hang HC, Pratt MR
Chemical reporters for fluorescent detection and identification of O-GlcNAc-modified proteins reveal glycosylation of the ubiquitin ligase NEDD4-1.
Proc Natl Acad Sci U S A 108: 8146-51 (2011)
PM ID: 21540332 PMC3100932
199: Trojer P, Cao AR, Gao Z, Li Y, Zhang J, Xu X, Li G, Losson R, Erdjument-Bromage H, Tempst P, Farnham PJ, Reinberg D
L3MBTL2 protein acts in concert with PcG protein-mediated monoubiquitination of H2A to establish a repressive chromatin structure.
Mol Cell 42: 438-50 (2011)
PM ID: 21596310 PMC3142354 NIHMS300350
200: Iyengar S, Ivanov AV, Jin VX, Rauscher FJ, Farnham PJ
Functional analysis of KAP1 genomic recruitment.
Mol Cell Biol 31: 1833-47 (2011)
PM ID: 21343339 PMC3133220
201: Kim S, Wang M, Lee AS, Thompson RF
Impaired eyeblink conditioning in 78 kDa-glucose regulated protein (GRP78)/immunoglobulin binding protein (BiP) conditional knockout mice.
Behav Neurosci 125: 404-11 (2011)
PM ID: 21517144
202: Bell D, Berchuck A, Birrer M, Chien J, Cramer D, Dao F, Dhir R, DiSaia P, Gabra H, Glenn P, Godwin A, Gross J, Hartmann L, Huang M, Huntsman D, Iacocca M, Imielinski M, Kalloger S, Karlan B, Levine D, Mills G, Morrison C, Mutch D, Olvera N, Orsulic S, Park K, Petrelli N, Rabeno B, Rader J, Sikic B, Smith-McCune K, Sood A, Bowtell D, Penny R, Testa J, Chang K, Dinh H, Drummond J, Fowler G, Gunaratne P, Hawes A, Kovar C, Lewis L, Morgan M, Newsham I, Santibanez J, Reid J, Trevino L, Wu Y-, Wang M, Muzny D, Wheeler D, Gibbs R, Getz G, Lawrence M, Cibulskis K, Sivachenko A, Sougnez C, Voet D, Wilkinson J, Bloom T, Ardlie K, Fennell T, Baldwin J, Gabriel S, Lander E, Ding LL, Fulton R, Koboldt D, McLellan M, Wylie T, Walker J, O'Laughlin M, Dooling D, Fulton L, Abbott R, Dees N, Zhang Q, Kandoth C, Wendl M, Schierding W, Shen D, Harris C, Schmidt H, Kalicki J, Delehaunty K, Fronick C, Demeter R, Cook L, Wallis J, Lin L, Magrini V, Hodges J, Eldred J, Smith S, Pohl C, Vandin F, Raphael B, Weinstock G, Mardis E, Wilson R, Meyerson M, Winckler W, Getz G, Verhaak R, Carter S, Mermel C, Saksena G, Nguyen H, Onofrio R, Lawrence M, Hubbard D, Gupta S, Crenshaw A, Ramos A, Ardlie K, Chin L, Protopopov A, Zhang J, Kim T, Perna I, Xiao Y, Zhang H, Ren G, Sathiamoorthy N, Park R, Lee E, Park P, Kucherlapati R, Absher M, Waite L, Sherlock G, Brooks J, Li J, Xu J, Myers R, Laird PW, Cope L, Herman J, Shen H, Weisenberger D, Noushmehr H, Pan F, Triche T, Berman B, Van Den Berg D, Buckley J, Baylin S, Spellman P, Purdom E, Neuvial P, Bengtsson H, Jakkula L, Durinck S, Han J, Dorton S, Marr H, Choi Y, Wang V, Wang N, Ngai J, Conboy J, Parvin B, Feiler H, Speed T, Gray J, Levine A, Socci N, Liang Y, Taylor B, Schultz N, Borsu L, Lash A, Brennan C, Viale A, Sander C, Ladanyi M, Hoadley K, Meng S, Du Y, Shi Y, Li L, Turman Y, Zang D, Helms E, Balu S, Zhou X, Wu J, Topal M, Hayes D, Perou C, Getz G, Voet D, Saksena G, Zhang J, Zhang H, Wu C, Shukla S, Cibulskis K, Lawrence M, Sivachenko A, Jing R, Park R, Liu Y, Park P, Noble M, Chin L, Carter H, Kim D, Karchin R, Spellman P, Purdom E, Neuvial P, Bengtsson H, Durinck S, Han J, Korkola J, Heiser L, Cho R, Hu Z, Parvin B, Speed T, Gray J, Schultz N, Cerami E, Taylor B, Olshen A, Reva B, Antipin Y, Shen R, Mankoo P, Sheridan R, Ciriello G, Chang W, Bernanke J, Borsu L, Levine D, Ladanyi M, Sander C, Haussler D, Benz C, Stuart J, Benz S, Sanborn J, Vaske C, Zhu J, Szeto C, Scott G, Yau C, Hoadley K, Du Y, Balu S, Hayes D, Perou C, Wilkerson M, Zhang N, Akbani R, Baggerly K, Yung W, Mills G, Weinstein J, Penny R, Shelton T, Grimm D, Hatfield M, Morris S, Yena P, Rhodes P, Sherman M, Paulauskis J, Millis S, Kahn A, Greene J, Sfeir R, Jensen M, Chen J, Whitmore J, Alonso S, Jordan J, Chu A, Zhang J, Barker A, Compton C, Eley G, Ferguson M, Fielding P, Gerhard D, Myles R, Schaefer C, Mills Shaw K, Vaught J, Vockley J, Good P, Guyer M, Ozenberger B, Peterson J, Thomson E, Cancer Genome Atlas Research Network
Integrated genomic analyses of ovarian carcinoma.
Nature 474: 609-15 (2011)
PM ID: 21720365 PMC3163504 NIHMS313090
203: Freedman ML, Monteiro AN, Gayther SA, Coetzee GA, Risch A, Plass C, Casey G, De Biasi M, Carlson C, Duggan D, James M, Liu P, Tichelaar JW, Vikis HG, You M, Mills IG
Principles for the post-GWAS functional characterization of cancer risk loci.
Nat Genet 43: 513-8 (2011)
PM ID: 21614091 PMC3325768 NIHMS305777
204: Weiss DJ, Bertoncello I, Borok Z, Kim C, Panoskaltsis-Mortari A, Reynolds S, Rojas M, Stripp B, Warburton D, Prockop DJ
Stem cells and cell therapies in lung biology and lung diseases.
Proc Am Thorac Soc 8: 223-72 (2011)
PM ID: 21653527 PMC3132784
205: Jiang TX, Tuan TL, Wu P, Widelitz RB, Chuong CM
From buds to follicles: matrix metalloproteinases in developmental tissue remodeling during feather morphogenesis.
Differentiation 81: 307-14 (2011)
PM ID: 21497985 PMC3114260 NIHMS286448
206: Siegmund KD
Statistical approaches for the analysis of DNA methylation microarray data.
Hum Genet 129: 585-95 (2011)
PM ID: 21519831 PMC3166559 NIHMS317655
207: Borok Z, Whitsett JA, Bitterman PB, Thannickal VJ, Kotton DN, Reynolds SD, Krasnow MA, Bianchi DW, Morrisey EE, Hogan BL, Kurie JM, Walker DC, Radisky DC, Nishimura SL, Violette SM, Noble PW, Shapiro SD, Blaisdell CJ, Chapman HA, Kiley J, Gail D, Hoshizaki D
Cell plasticity in lung injury and repair: report from an NHLBI workshop, April 19-20, 2010.
Proc Am Thorac Soc 8: 215-22 (2011)
PM ID: 21653526 PMC3132783
208: Lyu J, Jho EH, Lu W
Smek promotes histone deacetylation to suppress transcription of Wnt target gene brachyury in pluripotent embryonic stem cells.
Cell Res 21: 911-21 (2011)
PM ID: 21423269 PMC3203701
209: Parekh C, Jubran R, Erdreich-Epstein A, Panigrahy A, Bluml S, Finlay J, Dhall G
Treatment of children with recurrent high grade gliomas with a bevacizumab containing regimen.
J Neurooncol 103: 673-80 (2011)
PM ID: 21038110
210: Zhou H, Zhang Y, Fu Y, Chan L, Lee AS
Novel mechanism of anti-apoptotic function of 78-kDa glucose-regulated protein (GRP78): endocrine resistance factor in breast cancer, through release of B-cell lymphoma 2 (BCL-2) from BCL-2-interacting killer (BIK).
J Biol Chem 286: 25687-96 (2011)
PM ID: 21622563 PMC3138298
211: Breton CV, Byun HM, Wang X, Salam MT, Siegmund K, Gilliland FD
DNA methylation in the arginase-nitric oxide synthase pathway is associated with exhaled nitric oxide in children with asthma.
Am J Respir Crit Care Med 184: 191-7 (2011)
PM ID: 21512169 PMC3172885
212: Iyengar S, Farnham PJ
KAP1 protein: an enigmatic master regulator of the genome.
J Biol Chem 286: 26267-76 (2011)
PM ID: 21652716 PMC3143589
213: Ji C, Kaplowitz N, Lau MY, Kao E, Petrovic LM, Lee AS
Liver-specific loss of glucose-regulated protein 78 perturbs the unfolded protein response and exacerbates a spectrum of liver diseases in mice.
Hepatology 54: 229-39 (2011)
PM ID: 21503947 PMC3125405 NIHMS288241
214: Qiu X, Friedman JM, Liang G
Creating a flexible multiple microRNA expression vector by linking precursor microRNAs.
Biochem Biophys Res Commun 411: 276-80 (2011)
PM ID: 21726537 PMC3148277 NIHMS307892
215: Park E, Gang EJ, Hsieh YT, Schaefer P, Chae S, Klemm L, Huantes S, Loh M, Conway EM, Kang ES, Hoe Koo H, Hofmann WK, Heisterkamp N, Pelus L, Keerthivasan G, Crispino J, Kahn M, Müschen M, Kim YM
Targeting survivin overcomes drug resistance in acute lymphoblastic leukemia.
Blood 118: 2191-9 (2011)
PM ID: 21715311 PMC3162353
216: Davis-Dao CA, Siegmund KD, Vandenberg DJ, Skinner EC, Coetzee GA, Thomas DC, Pike MC, Cortessis VK
Heterogenous effect of androgen receptor CAG tract length on testicular germ cell tumor risk: shorter repeats associated with seminoma but not other histologic types.
Carcinogenesis 32: 1238-43 (2011)
PM ID: 21642359 PMC3202310
217: Buchanan G, Need EF, Barrett JM, Bianco-Miotto T, Thompson VC, Butler LM, Marshall VR, Tilley WD, Coetzee GA
Corepressor effect on androgen receptor activity varies with the length of the CAG encoded polyglutamine repeat and is dependent on receptor/corepressor ratio in prostate cancer cells.
Mol Cell Endocrinol 342: 20-31 (2011)
PM ID: 21664238 PMC3314496 NIHMS308521
218: Ye R, Ni M, Wang M, Luo S, Zhu G, Chow RH, Lee AS
Inositol 1,4,5-trisphosphate receptor 1 mutation perturbs glucose homeostasis and enhances susceptibility to diet-induced diabetes.
J Endocrinol 210: 209-17 (2011)
PM ID: 21565852 PMC3137733 NIHMS298818
219: You JS, Kelly TK, De Carvalho DD, Taberlay PC, Liang G, Jones PA
OCT4 establishes and maintains nucleosome-depleted regions that provide additional layers of epigenetic regulation of its target genes.
Proc Natl Acad Sci U S A 108: 14497-502 (2011)
PM ID: 21844352 PMC3167525
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Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.
Nature 476: 214-9 (2011)
PM ID: 21833088 PMC3182531
221: Hinch AG, Tandon A, Patterson N, Song Y, Rohland N, Palmer CD, Chen GK, Wang K, Buxbaum SG, Akylbekova EL, Aldrich MC, Ambrosone CB, Amos C, Bandera EV, Berndt SI, Bernstein L, Blot WJ, Bock CH, Boerwinkle E, Cai Q, Caporaso N, Casey G, Cupples LA, Deming SL, Diver WR, Divers J, Fornage M, Gillanders EM, Glessner J, Harris CC, Hu JJ, Ingles SA, Isaacs W, John EM, Kao WH, Keating B, Kittles RA, Kolonel LN, Larkin E, Le Marchand L, McNeill LH, Millikan RC, Murphy A, Musani S, Neslund-Dudas C, Nyante S, Papanicolaou GJ, Press MF, Psaty BM, Reiner AP, Rich SS, Rodriguez-Gil JL, Rotter JI, Rybicki BA, Schwartz AG, Signorello LB, Spitz M, Strom SS, Thun MJ, Tucker MA, Wang Z, Wiencke JK, Witte JS, Wrensch M, Wu X, Yamamura Y, Zanetti KA, Zheng W, Ziegler RG, Zhu X, Redline S, Hirschhorn JN, Henderson BE, Taylor HA, Price AL, Hakonarson H, Chanock SJ, Haiman CA, Wilson JG, Reich D, Myers SR
The landscape of recombination in African Americans.
Nature 476: 170-5 (2011)
PM ID: 21775986 PMC3154982 NIHMS313104
222: Linnemann AK, O'Geen H, Keles S, Farnham PJ, Bresnick EH
Genetic framework for GATA factor function in vascular biology.
Proc Natl Acad Sci U S A 108: 13641-6 (2011)
PM ID: 21808000 PMC3158141
223: Zhong Q, Zhou B, Ann DK, Minoo P, Liu Y, Banfalvi A, Krishnaveni MS, Dubourd M, Demaio L, Willis BC, Kim KJ, Dubois RM, Crandall ED, Beers MF, Borok Z
Role of endoplasmic reticulum stress in epithelial-mesenchymal transition of alveolar epithelial cells: effects of misfolded surfactant protein.
Am J Respir Cell Mol Biol 45: 498-509 (2011)
PM ID: 21169555 PMC3175581
224: Yu EJ, Kim SH, Heo K, Ou CY, Stallcup MR, Kim JH
Reciprocal roles of DBC1 and SIRT1 in regulating estrogen receptor α activity and co-activator synergy.
Nucleic Acids Res 39: 6932-43 (2011)
PM ID: 21596782 PMC3167635
225: Zaro BW, Bateman LA, Pratt MR
Robust in-gel fluorescence detection of mucin-type O-linked glycosylation.
Bioorg Med Chem Lett 21: 5062-6 (2011)
PM ID: 21531554
226: Wang J, Siegmund K, Tseng CC, Lee AS, Wu AH
Soy food supplementation, dietary fat reduction and peripheral blood gene expression in postmenopausal women--a randomized, controlled trial.
Mol Nutr Food Res 55 Suppl 2: S264-77 (2011)
PM ID: 21823222 PMC3819223 NIHMS518129
227: Fazlollahi F, Angelow S, Yacobi NR, Marchelletta R, Yu AS, Hamm-Alvarez SF, Borok Z, Kim KJ, Crandall ED
Polystyrene nanoparticle trafficking across MDCK-II.
Nanomedicine 7: 588-94 (2011)
PM ID: 21310266 PMC3130091 NIHMS273797
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Histone variant H3.3 stimulates HSP70 transcription through cooperation with HP1γ.
Nucleic Acids Res 39: 8329-41 (2011)
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A decade of exploring the cancer epigenome - biological and translational implications.
Nat Rev Cancer 11: 726-34 (2011)
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230: Kahn M
Symmetric division versus asymmetric division: a tale of two coactivators.
Future Med Chem 3: 1745-63 (2011)
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231: Winder T, Bohanes P, Zhang W, Yang D, Power DG, Ning Y, Gerger A, Wilson PM, Tang LH, Shah M, Lee AS, Lenz HJ
GRP78 promoter polymorphism rs391957 as potential predictor for clinical outcome in gastric and colorectal cancer patients.
Ann Oncol 22: 2431-9 (2011)
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232: Miki T, Yasuda SY, Kahn M
Wnt/β-catenin signaling in embryonic stem cell self-renewal and somatic cell reprogramming.
Stem Cell Rev 7: 836-46 (2011)
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233: Han H, Cortez CC, Yang X, Nichols PW, Jones PA, Liang G
DNA methylation directly silences genes with non-CpG island promoters and establishes a nucleosome occupied promoter.
Hum Mol Genet 20: 4299-310 (2011)
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234: Gerger A, Zhang W, Yang D, Bohanes P, Ning Y, Winder T, LaBonte MJ, Wilson PM, Benhaim L, Paez D, El-Khoueiry R, El-Khoueiry A, Kahn M, Lenz HJ
Common cancer stem cell gene variants predict colon cancer recurrence.
Clin Cancer Res 17: 6934-43 (2011)
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235: Cheng CF, Sahu D, Tsen F, Zhao Z, Fan J, Kim R, Wang X, O'Brien K, Li Y, Kuang Y, Chen M, Woodley DT, Li W
A fragment of secreted Hsp90α carries properties that enable it to accelerate effectively both acute and diabetic wound healing in mice.
J Clin Invest 121: 4348-61 (2011)
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236: Choi J, Kim H, Kim K, Lee B, Lu W, An W
Selective requirement of H2B N-Terminal tail for p14ARF-induced chromatin silencing.
Nucleic Acids Res 39: 9167-80 (2011)
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237: Purcell DJ, Jeong KW, Bittencourt D, Gerke DS, Stallcup MR
A distinct mechanism for coactivator versus corepressor function by histone methyltransferase G9a in transcriptional regulation.
J Biol Chem 286: 41963-71 (2011)
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238: Andreu-Vieyra C, Lai J, Berman BP, Frenkel B, Jia L, Jones PA, Coetzee GA
Dynamic nucleosome-depleted regions at androgen receptor enhancers in the absence of ligand in prostate cancer cells.
Mol Cell Biol 31: 4648-62 (2011)
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239: Tian Y, Sir D, Kuo CF, Ann DK, Ou JH
Autophagy required for hepatitis B virus replication in transgenic mice.
J Virol 85: 13453-6 (2011)
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240: Razzak AA, Oxentenko AS, Vierkant RA, Tillmans LS, Wang AH, Weisenberger DJ, Laird PW, Lynch CF, Anderson KE, French AJ, Haile RW, Harnack LJ, Slager SL, Smyrk TC, Thibodeau SN, Cerhan JR, Limburg PJ
Alcohol intake and colorectal cancer risk by molecularly defined subtypes in a prospective study of older women.
Cancer Prev Res (Phila) 4: 2035-43 (2011)
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241: Cortessis VK, Siegmund K, Houshdaran S, Laird PW, Sokol RZ
Repeated assessment by high-throughput assay demonstrates that sperm DNA methylation levels are highly reproducible.
Fertil Steril 96: 1325-30 (2011)
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242: Zeng N, Li Y, He L, Xu X, Galicia V, Deng C, Stiles BL
Adaptive basal phosphorylation of eIF2α is responsible for resistance to cellular stress-induced cell death in Pten-null hepatocytes.
Mol Cancer Res 9: 1708-17 (2011)
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243: Jeong KW, Kim K, Situ AJ, Ulmer TS, An W, Stallcup MR
Recognition of enhancer element-specific histone methylation by TIP60 in transcriptional activation.
Nat Struct Mol Biol 18: 1358-65 (2011)
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244: Taberlay PC, Kelly TK, Liu CC, You JS, De Carvalho DD, Miranda TB, Zhou XJ, Liang G, Jones PA
Polycomb-repressed genes have permissive enhancers that initiate reprogramming.
Cell 147: 1283-94 (2011)
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245: Noushmehr H, Coetzee GA
Identification and functional annotation of GWAS risk SNPs.
Cell Cycle 10: 3995-6 (2011)
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Screening ethnically diverse human embryonic stem cells identifies a chromosome 20 minimal amplicon conferring growth advantage.
Nat Biotechnol 29: 1132-44 (2011)
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247: Zhou X, Maricque B, Xie M, Li D, Sundaram V, Martin EA, Koebbe BC, Nielsen C, Hirst M, Farnham P, Kuhn RM, Zhu J, Smirnov I, Kent WJ, Haussler D, Madden PA, Costello JF, Wang T
The Human Epigenome Browser at Washington University.
Nat Methods 8: 989-90 (2011)
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248: Sharma S, Gerke DS, Han HF, Jeong S, Stallcup MR, Jones PA, Liang G
Lysine methyltransferase G9a is not required for DNMT3A/3B anchoring to methylated nucleosomes and maintenance of DNA methylation in somatic cells.
Epigenetics Chromatin 5: 3 (2012)
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249: Kennedy BA, Lan X, Huang TH, Farnham PJ, Jin VX
Using ChIPMotifs for de novo motif discovery of OCT4 and ZNF263 based on ChIP-based high-throughput experiments.
Methods Mol Biol 802: 323-34 (2012)
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250: Loo LW, Cheng I, Tiirikainen M, Lum-Jones A, Seifried A, Dunklee LM, Church JM, Gryfe R, Weisenberger DJ, Haile RW, Gallinger S, Duggan DJ, Thibodeau SN, Casey G, Le Marchand L
cis-Expression QTL analysis of established colorectal cancer risk variants in colon tumors and adjacent normal tissue.
PLoS One 7: e30477 (2012)
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251: Yang X, Noushmehr H, Han H, Andreu-Vieyra C, Liang G, Jones PA
Gene reactivation by 5-aza-2'-deoxycytidine-induced demethylation requires SRCAP-mediated H2A.Z insertion to establish nucleosome depleted regions.
PLoS Genet 8: e1002604 (2012)
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The transcription factor encyclopedia.
Genome Biol 13: R24 (2012)
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253: Brusslan JA, Rus Alvarez-Canterbury AM, Nair NU, Rice JC, Hitchler MJ, Pellegrini M
Genome-wide evaluation of histone methylation changes associated with leaf senescence in Arabidopsis.
PLoS One 7: e33151 (2012)
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254: Zhou B, Buckley ST, Patel V, Liu Y, Luo J, Krishnaveni MS, Ivan M, Demaio L, Kim KJ, Ehrhardt C, Crandall ED, Borok Z
Troglitazone attenuates TGF-β1-induced EMT in alveolar epithelial cells via a PPARγ-independent mechanism.
PLoS One 7: e38827 (2012)
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255: Wey S, Luo B, Lee AS
Acute inducible ablation of GRP78 reveals its role in hematopoietic stem cell survival, lymphogenesis and regulation of stress signaling.
PLoS One 7: e39047 (2012)
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256: Han H, Wolff EM, Liang G
Epigenetic alterations in bladder cancer and their potential clinical implications.
Adv Urol 2012: 546917 (2012)
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257: Ng CS, Wu P, Foley J, Foley A, McDonald ML, Juan WT, Huang CJ, Lai YT, Lo WS, Chen CF, Leal SM, Zhang H, Widelitz RB, Patel PI, Li WH, Chuong CM
The chicken frizzle feather is due to an α-keratin (KRT75) mutation that causes a defective rachis.
PLoS Genet 8: e1002748 (2012)
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258: Ren X, Xu J, Cooper JP, Kang MH, Erdreich-Epstein A
c-Abl is an upstream regulator of acid sphingomyelinase in apoptosis induced by inhibition of integrins αvβ3 and αvβ5.
PLoS One 7: e42291 (2012)
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259: Frietze S, Wang R, Yao L, Tak YG, Ye Z, Gaddis M, Witt H, Farnham PJ, Jin VX
Cell type-specific binding patterns reveal that TCF7L2 can be tethered to the genome by association with GATA3.
Genome Biol 13: R52 (2012)
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260: Razzak AA, Oxentenko AS, Vierkant RA, Tillmans LS, Wang AH, Weisenberger DJ, Laird PW, Lynch CF, Anderson KE, French AJ, Haile RW, Harnack LJ, Potter JD, Slager SL, Smyrk TC, Thibodeau SN, Cerhan JR, Limburg PJ
Associations between intake of folate and related micronutrients with molecularly defined colorectal cancer risks in the Iowa Women's Health Study.
Nutr Cancer 64: 899-910 (2012)
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261: Lange CP, Campan M, Hinoue T, Schmitz RF, van der Meulen-de Jong AE, Slingerland H, Kok PJ, van Dijk CM, Weisenberger DJ, Shen H, Tollenaar RA, Laird PW
Genome-scale discovery of DNA-methylation biomarkers for blood-based detection of colorectal cancer.
PLoS One 7: e50266 (2012)
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262: Lee SH, Toth Z, Wong LY, Brulois K, Nguyen J, Lee JY, Zandi E, Jung JU
Novel Phosphorylations of IKKγ/NEMO.
MBio 3: e00411-12 (2012)
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263: Wey S, Luo B, Tseng CC, Ni M, Zhou H, Fu Y, Bhojwani D, Carroll WL, Lee AS
Inducible knockout of GRP78/BiP in the hematopoietic system suppresses Pten-null leukemogenesis and AKT oncogenic signaling.
Blood 119: 817-25 (2012)
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264: Treppendahl MB, Qiu X, Søgaard A, Yang X, Nandrup-Bus C, Hother C, Andersen MK, Kjeldsen L, Möllgård L, Möllgaard L, Hellström-Lindberg E, Jendholm J, Porse BT, Jones PA, Liang G, Grønbaek K
Allelic methylation levels of the noncoding VTRNA2-1 located on chromosome 5q31.1 predict outcome in AML.
Blood 119: 206-16 (2012)
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265: Coetzee GA
The usefulness of prostate cancer genome-wide association studies.
J Urol 187: 9-10 (2012)
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266: Berman BP, Weisenberger DJ, Aman JF, Hinoue T, Ramjan Z, Liu Y, Noushmehr H, Lange CP, van Dijk CM, Tollenaar RA, Van Den Berg D, Laird PW
Regions of focal DNA hypermethylation and long-range hypomethylation in colorectal cancer coincide with nuclear lamina-associated domains.
Nat Genet 44: 40-6 (2012)
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267: Iwata J, Tung L, Urata M, Hacia JG, Pelikan R, Suzuki A, Ramenzoni L, Chaudhry O, Parada C, Sanchez-Lara PA, Chai Y
Fibroblast growth factor 9 (FGF9)-pituitary homeobox 2 (PITX2) pathway mediates transforming growth factor β (TGFβ) signaling to regulate cell proliferation in palatal mesenchyme during mouse palatogenesis.
J Biol Chem 287: 2353-63 (2012)
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268: Kang YA, Sanalkumar R, O'Geen H, Linnemann AK, Chang CJ, Bouhassira EE, Farnham PJ, Keles S, Bresnick EH
Autophagy driven by a master regulator of hematopoiesis.
Mol Cell Biol 32: 226-39 (2012)
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269: Hinoue T, Weisenberger DJ, Lange CP, Shen H, Byun HM, Van Den Berg D, Malik S, Pan F, Noushmehr H, van Dijk CM, Tollenaar RA, Laird PW
Genome-scale analysis of aberrant DNA methylation in colorectal cancer.
Genome Res 22: 271-82 (2012)
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270: Jenkins G, Blanchard A, Borok Z, Bradding P, Ehrhardt C, Fisher A, Hirani N, Johnson S, Königshoff M, Maher TM, Millar A, Parfrey H, Scotton C, Tetley T, Thickett D, Wolters P, ECIPF workshop
In search of the fibrotic epithelial cell: opportunities for a collaborative network.
Thorax 67: 179-82 (2012)
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271: Ianculescu I, Wu DY, Siegmund KD, Stallcup MR
Selective roles for cAMP response element-binding protein binding protein and p300 protein as coregulators for androgen-regulated gene expression in advanced prostate cancer cells.
J Biol Chem 287: 4000-13 (2012)
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272: Levine AJ, Win AK, Buchanan DD, Jenkins MA, Baron JA, Young JP, Long TI, Weisenberger DJ, Laird PW, McCall RL, Duggan DJ, Haile RW
Cancer risks for the relatives of colorectal cancer cases with a methylated MLH1 promoter region: data from the Colorectal Cancer Family Registry.
Cancer Prev Res (Phila) 5: 328-35 (2012)
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273: Sahu D, Zhao Z, Tsen F, Cheng CF, Park R, Situ AJ, Dai J, Eginli A, Shams S, Chen M, Ulmer TS, Conti P, Woodley DT, Li W
A potentially common peptide target in secreted heat shock protein-90α for hypoxia-inducible factor-1α-positive tumors.
Mol Biol Cell 23: 602-13 (2012)
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274: Chimge NO, Baniwal SK, Luo J, Coetzee S, Khalid O, Berman BP, Tripathy D, Ellis MJ, Frenkel B
Opposing effects of Runx2 and estradiol on breast cancer cell proliferation: in vitro identification of reciprocally regulated gene signature related to clinical letrozole responsiveness.
Clin Cancer Res 18: 901-11 (2012)
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275: Kim K, Heo K, Choi J, Jackson S, Kim H, Xiong Y, An W
Vpr-binding protein antagonizes p53-mediated transcription via direct interaction with H3 tail.
Mol Cell Biol 32: 783-96 (2012)
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276: Kim H, Kim K, Choi J, Heo K, Baek HJ, Roeder RG, An W
p53 requires an intact C-terminal domain for DNA binding and transactivation.
J Mol Biol 415: 843-54 (2012)
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277: Choi I, Lee S, Kyoung Chung H, Suk Lee Y, Eui Kim K, Choi D, Park EK, Yang D, Ecoiffier T, Monahan J, Chen W, Aguilar B, Lee HN, Yoo J, Koh CJ, Chen L, Wong AK, Hong YK
9-cis retinoic acid promotes lymphangiogenesis and enhances lymphatic vessel regeneration: therapeutic implications of 9-cis retinoic acid for secondary lymphedema.
Circulation 125: 872-82 (2012)
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278: Moon BC, Hernandez-Ono A, Stiles B, Wu H, Ginsberg HN
Apolipoprotein B secretion is regulated by hepatic triglyceride, and not insulin, in a model of increased hepatic insulin signaling.
Arterioscler Thromb Vasc Biol 32: 236-46 (2012)
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279: Li W, Sahu D, Tsen F
Secreted heat shock protein-90 (Hsp90) in wound healing and cancer.
Biochim Biophys Acta 1823: 730-41 (2012)
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280: Demaio L, Buckley ST, Krishnaveni MS, Flodby P, Dubourd M, Banfalvi A, Xing Y, Ehrhardt C, Minoo P, Zhou B, Crandall ED, Borok Z
Ligand-independent transforming growth factor-β type I receptor signalling mediates type I collagen-induced epithelial-mesenchymal transition.
J Pathol 226: 633-44 (2012)
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281: Davis-Dao C, Koh CJ, Hardy BE, Chang A, Kim SS, De Filippo R, Hwang A, Pike MC, Carroll JD, Coetzee GA, VanDenBerg D, Siegmund K, Cortessis VK
Shorter androgen receptor CAG repeat lengths associated with cryptorchidism risk among Hispanic white boys.
J Clin Endocrinol Metab 97: E393-9 (2012)
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282: Zhou B, Liu Y, Kahn M, Ann DK, Han A, Wang H, Nguyen C, Flodby P, Zhong Q, Krishnaveni MS, Liebler JM, Minoo P, Crandall ED, Borok Z
Interactions between β-catenin and transforming growth factor-β signaling pathways mediate epithelial-mesenchymal transition and are dependent on the transcriptional co-activator cAMP-response element-binding protein (CREB)-binding protein (CBP).
J Biol Chem 287: 7026-38 (2012)
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283: Iwata J, Hacia JG, Suzuki A, Sanchez-Lara PA, Urata M, Chai Y
Modulation of noncanonical TGF-β signaling prevents cleft palate in Tgfbr2 mutant mice.
J Clin Invest 122: 873-85 (2012)
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284: Lin HH, Li X, Chen JL, Sun X, Cooper FN, Chen YR, Zhang W, Chung Y, Li A, Cheng CT, Yang L, Deng X, Liu X, Yen Y, Johnson DL, Shih HM, Yang A, Ann DK
Identification of an AAA ATPase VPS4B-dependent pathway that modulates epidermal growth factor receptor abundance and signaling during hypoxia.
Mol Cell Biol 32: 1124-38 (2012)
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285: Meier F, Abeywardana T, Dhall A, Marotta NP, Varkey J, Langen R, Chatterjee C, Pratt MR
Semisynthetic, site-specific ubiquitin modification of α-synuclein reveals differential effects on aggregation.
J Am Chem Soc 134: 5468-71 (2012)
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286: Yang CS, Lee JS, Rodgers M, Min CK, Lee JY, Kim HJ, Lee KH, Kim CJ, Oh B, Zandi E, Yue Z, Kramnik I, Liang C, Jung JU
Autophagy protein Rubicon mediates phagocytic NADPH oxidase activation in response to microbial infection or TLR stimulation.
Cell Host Microbe 11: 264-76 (2012)
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287: Wang J, Joshi AD, Corral R, Siegmund KD, Marchand LL, Martinez ME, Haile RW, Ahnen DJ, Sandler RS, Lance P, Stern MC
Carcinogen metabolism genes, red meat and poultry intake, and colorectal cancer risk.
Int J Cancer 130: 1898-907 (2012)
PM ID: 21618522 PMC3883510 NIHMS320311
288: Little GH, Noushmehr H, Baniwal SK, Berman BP, Coetzee GA, Frenkel B
Genome-wide Runx2 occupancy in prostate cancer cells suggests a role in regulating secretion.
Nucleic Acids Res 40: 3538-47 (2012)
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289: Xu J, Erdreich-Epstein A, Gonzalez-Gomez I, Melendez EY, Smbatyan G, Moats RA, Rosol M, Biegel JA, Reynolds CP
Novel cell lines established from pediatric brain tumors.
J Neurooncol 107: 269-80 (2012)
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290: Yoo SA, You S, Yoon HJ, Kim DH, Kim HS, Lee K, Ahn JH, Hwang D, Lee AS, Kim KJ, Park YJ, Cho CS, Kim WU
A novel pathogenic role of the ER chaperone GRP78/BiP in rheumatoid arthritis.
J Exp Med 209: 871-86 (2012)
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291: Zhang H, Liu H, Borok Z, Davies KJ, Ursini F, Forman HJ
Cigarette smoke extract stimulates epithelial-mesenchymal transition through Src activation.
Free Radic Biol Med 52: 1437-42 (2012)
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292: Kerin T, Ramanathan A, Rivas K, Grepo N, Coetzee GA, Campbell DB
A noncoding RNA antisense to moesin at 5p14.1 in autism.
Sci Transl Med 4: 128ra40 (2012)
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293: Chuong CM, Randall VA, Widelitz RB, Wu P, Jiang TX
Physiological regeneration of skin appendages and implications for regenerative medicine.
Physiology (Bethesda) 27: 61-72 (2012)
PM ID: 22505663 PMC3620028 NIHMS444851
294: Ting MC, Liao CP, Yan C, Jia L, Groshen S, Frenkel B, Roy-Burman P, Coetzee GA, Maxson R
An enhancer from the 8q24 prostate cancer risk region is sufficient to direct reporter gene expression to a subset of prostate stem-like epithelial cells in transgenic mice.
Dis Model Mech 5: 366-74 (2012)
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A TGFβ-Smad4-Fgf6 signaling cascade controls myogenic differentiation and myoblast fusion during tongue development.
Development 139: 1640-50 (2012)
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296: Xing Y, Li A, Borok Z, Li C, Minoo P
NOTCH1 is required for regeneration of Clara cells during repair of airway injury.
Stem Cells 30: 946-55 (2012)
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DNA methylation screening identifies driver epigenetic events of cancer cell survival.
Cancer Cell 21: 655-67 (2012)
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Choroid plexus tumors; management, outcome, and association with the Li-Fraumeni syndrome: the Children's Hospital Los Angeles (CHLA) experience, 1991-2010.
Pediatr Blood Cancer 58: 905-9 (2012)
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299: Won Jeong K, Chodankar R, Purcell DJ, Bittencourt D, Stallcup MR
Gene-specific patterns of coregulator requirements by estrogen receptor-α in breast cancer cells.
Mol Endocrinol 26: 955-66 (2012)
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300: Yen HY, Gabet Y, Liu Y, Martin A, Wu NL, Pike MC, Frenkel B, Maxson R, Dubeau L
Alterations in Brca1 expression in mouse ovarian granulosa cells have short-term and long-term consequences on estrogen-responsive organs.
Lab Invest 92: 802-11 (2012)
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301: Tong C, Huang G, Ashton C, Wu H, Yan H, Ying QL
Rapid and cost-effective gene targeting in rat embryonic stem cells by TALENs.
J Genet Genomics 39: 275-80 (2012)
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302: Purcell DJ, Khalid O, Ou CY, Little GH, Frenkel B, Baniwal SK, Stallcup MR
Recruitment of coregulator G9a by Runx2 for selective enhancement or suppression of transcription.
J Cell Biochem 113: 2406-14 (2012)
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303: Jung CJ, Iyengar S, Blahnik KR, Jiang JX, Tahimic C, Torok NJ, De Vere White RW, Farnham PJ, Zern M
Human ESC self-renewal promoting microRNAs induce epithelial-mesenchymal transition in hepatocytes by controlling the PTEN and TGFβ tumor suppressor signaling pathways.
Mol Cancer Res 10: 979-91 (2012)
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304: Jones PA
Functions of DNA methylation: islands, start sites, gene bodies and beyond.
Nat Rev Genet 13: 484-92 (2012)
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305: Selamat SA, Chung BS, Girard L, Zhang W, Zhang Y, Campan M, Siegmund KD, Koss MN, Hagen JA, Lam WL, Lam S, Gazdar AF, Laird-Offringa IA
Genome-scale analysis of DNA methylation in lung adenocarcinoma and integration with mRNA expression.
Genome Res 22: 1197-211 (2012)
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Environ Health Perspect 120: 1320-6 (2012)
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Nucleic Acids Res 40: 7690-704 (2012)
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Nature 489: 519-25 (2012)
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Genome Res 22: 1813-31 (2012)
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Nature 489: 57-74 (2012)
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Curr Opin Pulm Med 18: 517-23 (2012)
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An essential role of variant histone H3.3 for ectomesenchyme potential of the cranial neural crest.
PLoS Genet 8: e1002938 (2012)
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FunciSNP: an R/bioconductor tool integrating functional non-coding data sets with genetic association studies to identify candidate regulatory SNPs.
Nucleic Acids Res 40: e139 (2012)
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Hum Genet 131: 1565-89 (2012)
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Nucleic Acids Res 40: 9379-91 (2012)
PM ID: 22879375 PMC3479191
331: Koboldt DC, Fulton RS, McLellan MD, Schmidt H, Kalicki-Veizer J, McMichael JF, Fulton LL, Dooling DJ, Ding L, Mardis ER, Wilson RK, Ally A, Balasundaram M, Butterfield YS, Carlsen R, Carter C, Chu A, Chuah E, Chun HJ, Coope RJ, Dhalla N, Guin R, Hirst C, Hirst M, Holt RA, Lee D, Li HI, Mayo M, Moore RA, Mungall AJ, Pleasance E, Robertson A, Schein JE, Shafiei A, Sipahimalani P, Slobodan JR, Stoll D, Tam A, Thiessen N, Varhol RJ, Wye N, Zeng T, Zhao Y, Birol I, Jones SJ, Marra MA, Cherniack AD, Saksena G, Onofrio RC, Pho NH, Carter SL, Schumacher SE, Tabak B, Hernandez B, Gentry J, Nguyen H, Crenshaw A, Ardlie K, Beroukhim R, Winckler W, Getz G, Gabriel SB, Meyerson M, Chin L, Park PJ, Kucherlapati R, Hoadley KA, Auman J, Fan C, Turman YJ, Shi Y, Li L, Topal MD, He X, Chao HH, Prat A, Silva GO, Iglesia MD, Zhao W, Usary J, Berg JS, Adams M, Booker J, Wu J, Gulabani A, Bodenheimer T, Hoyle AP, Simons JV, Soloway MG, Mose LE, Jefferys SR, Balu S, Parker JS, Hayes D, Perou CM, Malik S, Mahurkar S, Shen H, Weisenberger DJ, Triche T, Lai PH, Bootwalla MS, Maglinte DT, Berman BP, Van Den Berg DJ, Baylin SB, Laird PW, Creighton CJ, Donehower LA, Getz G, Noble M, Voet D, Saksena G, Gehlenborg N, DiCara D, Zhang J, Zhang H, Wu CJ, Liu SY, Lawrence MS, Zou L, Sivachenko A, Lin P, Stojanov P, Jing R, Cho J, Sinha R, Park RW, Nazaire MD, Robinson J, Thorvaldsdottir H, Mesirov J, Park PJ, Chin L, Reynolds S, Kreisberg RB, Bernard B, Bressler R, Erkkila T, Lin J, Thorsson V, Zhang W, Shmulevich I, Ciriello G, Weinhold N, Schultz N, Gao J, Cerami E, Gross B, Jacobsen A, Sinha R, Aksoy B, Antipin Y, Reva B, Shen R, Taylor BS, Ladanyi M, Sander C, Anur P, Spellman PT, Lu Y, Liu W, Verhaak RR, Mills GB, Akbani R, Zhang N, Broom BM, Casasent TD, Wakefield C, Unruh AK, Baggerly K, Coombes K, Weinstein JN, Haussler D, Benz CC, Stuart JM, Benz SC, Zhu J, Szeto CC, Scott GK, Yau C, Paull EO, Carlin D, Wong C, Sokolov A, Thusberg J, Mooney S, Ng S, Goldstein TC, Ellrott K, Grifford M, Wilks C, Ma S, Craft B, Yan C, Hu Y, Meerzaman D, Gastier-Foster JM, Bowen J, Ramirez NC, Black AD, Pyatt RE, White P, Zmuda EJ, Frick J, Lichtenberg TM, Brookens R, George MM, Gerken MA, Harper HA, Leraas KM, Wise LJ, Tabler TR, McAllister C, Barr T, Hart-Kothari M, Tarvin K, Saller C, Sandusky G, Mitchell C, Iacocca MV, Brown J, Rabeno B, Czerwinski C, Petrelli N, Dolzhansky O, Abramov M, Voronina O, Potapova O, Marks JR, Suchorska WM, Murawa D, Kycler W, Ibbs M, Korski K, Spychała A, Murawa P, Brzeziński JJ, Perz H, Łaźniak R, Teresiak M, Tatka H, Leporowska E, Bogusz-Czerniewicz M, Malicki J, Mackiewicz A, Wiznerowicz M, Le XV, Kohl B, Nguyen VT, Thorp R, Nguyen VB, Sussman H, Bui DP, Hajek R, Nguyen PH, Tran VT, Huynh QT, Khan KZ, Penny R, Mallery D, Curley E, Shelton C, Yena P, Ingle JN, Couch FJ, Lingle WL, King TA, Gonzalez-Angulo AM, Mills GB, Dyer MD, Liu S, Meng X, Patangan M, Waldman F, Stöppler H, Rathmell W, Thorne L, Huang M, Boice L, Hill A, Morrison C, Gaudioso C, Bshara W, Daily K, Egea SC, Pegram M, Gomez-Fernandez C, Dhir R, Bhargava R, Brufsky A, Shriver CD, Hooke JA, Campbell JL, Mural RJ, Hu H, Somiari S, Larson C, Deyarmin B, Kvecher L, Kovatich AJ, Ellis MJ, King TA, Hu H, Couch FJ, Mural RJ, Stricker T, White K, Olopade O, Ingle JN, Luo C, Chen Y, Marks JR, Waldman F, Wiznerowicz M, Bose R, Chang LW, Beck AH, Gonzalez-Angulo AM, Pihl T, Jensen M, Sfeir R, Kahn A, Chu A, Kothiyal P, Wang Z, Snyder E, Pontius J, Ayala B, Backus M, Walton J, Baboud J, Berton D, Nicholls M, Srinivasan D, Raman R, Girshik S, Kigonya P, Alonso S, Sanbhadti R, Barletta S, Pot D, Sheth M, Demchok JA, Shaw KR, Yang L, Eley G, Ferguson ML, Tarnuzzer RW, Zhang J, Dillon LA, Buetow K, Fielding P, Ozenberger BA, Guyer MS, Sofia HJ, Palchik JD, Cancer Genome Atlas Network
Comprehensive molecular portraits of human breast tumours.
Nature 490: 61-70 (2012)
PM ID: 23000897 PMC3465532 NIHMS393293
332: Xu S, Butkevich AN, Yamada R, Zhou Y, Debnath B, Duncan R, Zandi E, Petasis NA, Neamati N
Discovery of an orally active small-molecule irreversible inhibitor of protein disulfide isomerase for ovarian cancer treatment.
Proc Natl Acad Sci U S A 109: 16348-53 (2012)
PM ID: 22988091 PMC3479552
333: Tewari AK, Yardimci GG, Shibata Y, Sheffield NC, Song L, Taylor BS, Georgiev SG, Coetzee GA, Ohler U, Furey TS, Crawford GE, Febbo PG
Chromatin accessibility reveals insights into androgen receptor activation and transcriptional specificity.
Genome Biol 13: R88 (2012)
PM ID: 23034120 PMC3491416
334: Wang XM, Yik WY, Zhang P, Lu W, Dranchak PK, Shibata D, Steinberg SJ, Hacia JG
The gene expression profiles of induced pluripotent stem cells from individuals with childhood cerebral adrenoleukodystrophy are consistent with proposed mechanisms of pathogenesis.
Stem Cell Res Ther 3: 39 (2012)
PM ID: 23036268 PMC3580430
335: Ishii M, Arias AC, Liu L, Chen YB, Bronner ME, Maxson RE
A stable cranial neural crest cell line from mouse.
Stem Cells Dev 21: 3069-80 (2012)
PM ID: 22889333 PMC3495126
336: Tiozzo C, Carraro G, Al Alam D, Baptista S, Danopoulos S, Li A, Lavarreda-Pearce M, Li C, De Langhe S, Chan B, Borok Z, Bellusci S, Minoo P
Mesodermal Pten inactivation leads to alveolar capillary dysplasia- like phenotype.
J Clin Invest 122: 3862-72 (2012)
PM ID: 23023706 PMC3484434
337: Chen Y, Bates DL, Dey R, Chen PH, Machado AC, Laird-Offringa IA, Rohs R, Chen L
DNA binding by GATA transcription factor suggests mechanisms of DNA looping and long-range gene regulation.
Cell Rep 2: 1197-206 (2012)
PM ID: 23142663 PMC3978094 NIHMS417448
338: Bittencourt D, Wu DY, Jeong KW, Gerke DS, Herviou L, Ianculescu I, Chodankar R, Siegmund KD, Stallcup MR
G9a functions as a molecular scaffold for assembly of transcriptional coactivators on a subset of glucocorticoid receptor target genes.
Proc Natl Acad Sci U S A 109: 19673-8 (2012)
PM ID: 23151507 PMC3511704
339: Nielsen CB, Younesy H, O'Geen H, Xu X, Jackson AR, Milosavljevic A, Wang T, Costello JF, Hirst M, Farnham PJ, Jones SJ
Spark: a navigational paradigm for genomic data exploration.
Genome Res 22: 2262-9 (2012)
PM ID: 22960372 PMC3483555
340: Pfaffenbach KT, Pong M, Morgan TE, Wang H, Ott K, Zhou B, Longo VD, Lee AS
GRP78/BiP is a novel downstream target of IGF-1 receptor mediated signaling.
J Cell Physiol 227: 3803-11 (2012)
PM ID: 22422508 PMC3421054 NIHMS364068
341: Li J, Jiang TX, Hughes MW, Wu P, Yu J, Widelitz RB, Fan G, Chuong CM
Progressive alopecia reveals decreasing stem cell activation probability during aging of mice with epidermal deletion of DNA methyltransferase 1.
J Invest Dermatol 132: 2681-90 (2012)
PM ID: 22763785 PMC3465630 NIHMS378674
342: Yue Z, Jiang TX, Wu P, Widelitz RB, Chuong CM
Sprouty/FGF signaling regulates the proximal-distal feather morphology and the size of dermal papillae.
Dev Biol 372: 45-54 (2012)
PM ID: 23000358 PMC3586415 NIHMS408974
343: Kelly TK, Liu Y, Lay FD, Liang G, Berman BP, Jones PA
Genome-wide mapping of nucleosome positioning and DNA methylation within individual DNA molecules.
Genome Res 22: 2497-506 (2012)
PM ID: 22960375 PMC3514679
344: Siddiq A, Couch FJ, Chen GK, Lindström S, Eccles D, Millikan RC, Michailidou K, Stram DO, Beckmann L, Rhie SK, Ambrosone CB, Aittomäki K, Amiano P, Apicella C, Australian Breast Cancer Tissue Bank Investigators , Baglietto L, Bandera EV, Beckmann MW, Berg CD, Bernstein L, Blomqvist C, Brauch H, Brinton L, Bui QM, Buring JE, Buys SS, Campa D, Carpenter JE, Chasman DI, Chang-Claude J, Chen C, Clavel-Chapelon F, Cox A, Cross SS, Czene K, Deming SL, Diasio RB, Diver WR, Dunning AM, Durcan L, Ekici AB, Fasching PA, Familial Breast Cancer Study , Feigelson HS, Fejerman L, Figueroa JD, Fletcher O, Flesch-Janys D, Gaudet MM, GENICA Consortium , Gerty SM, Rodriguez-Gil JL, Giles GG, van Gils CH, Godwin AK, Graham N, Greco D, Hall P, Hankinson SE, Hartmann A, Hein R, Heinz J, Hoover RN, Hopper JL, Hu JJ, Huntsman S, Ingles SA, Irwanto A, Isaacs C, Jacobs KB, John EM, Justenhoven C, Kaaks R, Kolonel LN, Coetzee GA, Lathrop M, Le Marchand L, Lee AM, Lee IM, Lesnick T, Lichtner P, Liu J, Lund E, Makalic E, Martin NG, McLean CA, Meijers-Heijboer H, Meindl A, Miron P, Monroe KR, Montgomery GW, Müller-Myhsok B, Nickels S, Nyante SJ, Olswold C, Overvad K, Palli D, Park DJ, Palmer JR, Pathak H, Peto J, Pharoah P, Rahman N, Rivadeneira F, Schmidt DF, Schmutzler RK, Slager S, Southey MC, Stevens KN, Sinn HP, Press MF, Ross E, Riboli E, Ridker PM, Schumacher FR, Severi G, Dos Santos Silva I, Stone J, Sund M, Tapper WJ, Thun MJ, Travis RC, Turnbull C, Uitterlinden AG, Waisfisz Q, Wang X, Wang Z, Weaver J, Schulz-Wendtland R, Wilkens LR, Van Den Berg D, Zheng W, Ziegler RG, Ziv E, Nevanlinna H, Easton DF, Hunter DJ, Henderson BE, Chanock SJ, Garcia-Closas M, Kraft P, Haiman CA, Vachon CM
A meta-analysis of genome-wide association studies of breast cancer identifies two novel susceptibility loci at 6q14 and 20q11.
Hum Mol Genet 21: 5373-84 (2012)
PM ID: 22976474 PMC3510753
345: Jones PA, Baylin SB, Bernstein BE, Clark S, Greally JM, Laird PW, Schübeler D, Ushijima T, Amati B, Beck S, Campbell RM, Carpten JD, Chinnaiyan AM, Costello JF, Dhanak D, Ecker JR, Esteller M, Helin K, Herman JG, Issa JP, Jackson-Grusby L, Kim YJ, Licht JD, Liu XS, Ng HH, Polyak K, Reinberg D, Richon VM, Stunnenberg H, Tycko B, Wang J, Beck S, Bernstein BE, Campbell RM, Costello JF, Dhanak D, Ecker JR, Greally JM, Issa JP, Laird PW, Polyak K, Tycko B, Jones PA, AACR Cancer Epigenome Task Force
A blueprint for an international cancer epigenome consortium. A report from the AACR Cancer Epigenome Task Force.
Cancer Res 72: 6319-24 (2012)
PM ID: 23188507
346: Marotta NP, Cherwien CA, Abeywardana T, Pratt MR
O-GlcNAc modification prevents peptide-dependent acceleration of α-synuclein aggregation.
Chembiochem 13: 2665-70 (2012)
PM ID: 23143740
347: Han A, Bandyopadhyay B, Jayaprakash P, Lua I, Sahu D, Chen M, Woodley DT, Li W
The anti-motility signaling mechanism of TGFβ3 that controls cell traffic during skin wound healing.
Biol Open 1: 1169-77 (2012)
PM ID: 23259050 PMC3522877
348: Andreu-Vieyra CV, Liang G
Nucleosome occupancy and gene regulation during tumorigenesis.
Adv Exp Med Biol 754: 109-34 (2013)
PM ID: 22956498
349: Wu H, Chen L, Zhang X, Zhou Q, Li JM, Berger S, Borok Z, Zhou B, Xiao Z, Yin H, Liu M, Wang Y, Jin J, Blackburn MR, Xia Y, Zhang W
Aqp5 is a new transcriptional target of Dot1a and a regulator of Aqp2.
PLoS One 8: e53342 (2013)
PM ID: 23326416 PMC3542343
350: Zaro BW, Hang HC, Pratt MR
Incorporation of unnatural sugars for the identification of glycoproteins.
Methods Mol Biol 951: 57-67 (2013)
PM ID: 23296524
351: Gao F, Shi L, Russin J, Zeng L, Chang X, He S, Chen TC, Giannotta SL, Weisenberger DJ, Zada G, Mack WJ, Wang K
DNA methylation in the malignant transformation of meningiomas.
PLoS One 8: e54114 (2013)
PM ID: 23349797 PMC3551961
352: Li W, Tsen F, Sahu D, Bhatia A, Chen M, Multhoff G, Woodley DT
Extracellular Hsp90 (eHsp90) as the actual target in clinical trials: intentionally or unintentionally.
Int Rev Cell Mol Biol 303: 203-35 (2013)
PM ID: 23445811 PMC4023563 NIHMS580669
353: Whiteman DC, Webb PM, Phil D, Green AC, Hayward NK, Parsons PG, Purdie DM, Smithers B, Gotley D, Clouston A, Brown I, Moore S, Harrap K, Sadkowski T, O'Brien S, Minehan E, Roffe D, O'Keefe S, Lipshut S, Connor G, Berry H, Walker F, Barnes T, Thomas J, Terry L, Connard M, Bowes L, Malt M, White J, Mosse C, Tait N, Bambach C, Biankan A, Brancatisano R, Coleman M, Cox M, Deane S, Falk GL, Gallagher J, Hollands M, Hugh T, Hunt D, Jorgensen J, Martin C, Richardson M, Smith G, Smith R, Storey D, Avramovic J, Croese J, D'Arcy J, Fairley S, Hansen J, Masson J, Nathanson L, O'Loughlin B, Rutherford L, Turner R, Windsor M, Bessell J, Devitt P, Jamieson G, Watson D, Blamey S, Boussioutas A, Cade R, Crosthwaite G, Faragher I, Gribbin J, Hebbard G, Kiroff G, Mann B, Millar B, O'Brien P, Thomas R, Wood S, Archer S, Faulkner K, Hamdorf J, Stuart-Harris R, Bowtell D, Gertig D, Green A, Defazio A, Webb P, Kirsten F, Rutovitz J, Clingan P, Glasgow A, Proietto A, Braye S, Otton G, Shannon J, Bonaventura T, Stewart J, Begbie S, Friedlander M, Bell D, Baron-Hay S, Ferrier A, Gard G, Nevell D, Pavlakis N, Valmadre S, Young B, Camaris C, Crouch R, Edwards L, Hacker N, Marsden D, Robertson G, Beale P, Beith J, Carter J, Dalrymple C, Houghton R, Russell P, Anderson L, Links M, Grygiel J, Hill J, Brand A, Byth K, Jaworski R, Harnett P, Sharma R, Wain G, Purdie D, Whiteman D, Ward B, Papadimos D, Crandon A, Cummings M, Horwood K, Obermair A, Perrin L, Wyld D, Nicklin J, Davy M, Oehler MK, Hall C, Dodd T, Healy T, Pittman K, Henderson D, Miller J, Pierdes J, Achan A, Blomfield P, Challis D, McIntosh R, Parker A, Brown B, Rome R, Allen D, Grant P, Hyde S, Laurie R, Robbie M, Healy D, Jobling T, Manolitsas T, McNealage J, Rogers P, Susil B, Sumithran E, Simpson I, Haviv I, Phillips K, Rischin D, Fox S, Johnson D, Lade S, Waring P, Loughrey M, O'Callaghan N, Murray B, Mileshkin L, Allan P, Billson V, Pyman J, Neesham D, Quinn M, Hamilton A, Underhill C, Bell R, Ng LF, Blum R, Ganju V, Hammond I, McCartney A, Stewart C, Leung Y, Buck M, Zeps N, Andrulis IL, Caldes T, Caligo MA, Sinilnikova O, Hansen TV, Rookus M, Hogervorst F, Jakubowska A, Lubinski J, Peock S, Chenevix-Trench G, Nathanson KL, Domchek S, Nevanlinna H, Offit K, Osorio A, Benitez J, Radice P, Singer CF, Schmutzler R, Godwin A, Blanco I, Lazaro C, Montagna M, Beattie MS, Antoniou AC, Easton DF, Couch FJ, Permuth-Wey J, Lawrenson K, Shen HC, Velkova A, Tyrer JP, Chen Z, Lin HY, Chen YA, Tsai YY, Qu X, Ramus SJ, Karevan R, Lee J, Lee N, Larson MC, Aben KK, Anton-Culver H, Antonenkova N, Antoniou AC, Armasu SM, Australian Cancer Study , Australian Ovarian Cancer Study , Bacot F, Baglietto L, Bandera EV, Barnholtz-Sloan J, Beckmann MW, Birrer MJ, Bloom G, Bogdanova N, Brinton LA, Brooks-Wilson A, Brown R, Butzow R, Cai Q, Campbell I, Chang-Claude J, Chanock S, Chenevix-Trench G, Cheng JQ, Cicek MS, Coetzee GA, Consortium of Investigators of Modifiers of BRCA1/2 , Cook LS, Couch FJ, Cramer DW, Cunningham JM, Dansonka-Mieszkowska A, Despierre E, Doherty JA, Dörk T, du Bois A, Dürst M, Easton DF, Eccles D, Edwards R, Ekici AB, Fasching PA, Fenstermacher DA, Flanagan JM, Garcia-Closas M, Gentry-Maharaj A, Giles GG, Glasspool RM, Gonzalez-Bosquet J, Goodman MT, Gore M, Górski B, Gronwald J, Hall P, Halle MK, Harter P, Heitz F, Hillemanns P, Hoatlin M, Høgdall CK, Høgdall E, Hosono S, Jakubowska A, Jensen A, Jim H, Kalli KR, Karlan BY, Kaye SB, Kelemen LE, Kiemeney LA, Kikkawa F, Konecny GE, Krakstad C, Kjaer SK, Kupryjanczyk J, Lambrechts D, Lambrechts S, Lancaster JM, Le ND, Leminen A, Levine DA, Liang D, Lim BK, Lin J, Lissowska J, Lu KH, Lubinski J, Lurie G, Massuger LF, Matsuo K, McGuire V, McLaughlin JR, Menon U, Modugno F, Moysich KB, Nakanishi T, Narod SA, Nedergaard L, Ness RB, Nevanlinna H, Nickels S, Noushmehr H, Odunsi K, Olson SH, Orlow I, Paul J, Pearce CL, Pejovic T, Pelttari LM, Pike MC, Poole EM, Raska P, Renner SP, Risch HA, Rodriguez-Rodriguez L, Rossing MA, Rudolph A, Runnebaum IB, Rzepecka IK, Salvesen HB, Schwaab I, Severi G, Shridhar V, Shu XO, Shvetsov YB, Sieh W, Song H, Southey MC, Spiewankiewicz B, Stram D, Sutphen R, Teo SH, Terry KL, Tessier DC, Thompson PJ, Tworoger SS, van Altena AM, Vergote I, Vierkant RA, Vincent D, Vitonis AF, Wang-Gohrke S, Palmieri Weber R, Wentzensen N, Whittemore AS, Wik E, Wilkens LR, Winterhoff B, Woo YL, Wu AH, Xiang YB, Yang HP, Zheng W, Ziogas A, Zulkifli F, Phelan CM, Iversen E, Schildkraut JM, Berchuck A, Fridley BL, Goode EL, Pharoah PD, Monteiro AN, Sellers TA, Gayther SA
Identification and molecular characterization of a new ovarian cancer susceptibility locus at 17q21.31.
Nat Commun 4: 1627 (2013)
PM ID: 23535648 PMC3709460 NIHMS447293
354: O'Rawe J, Jiang T, Sun G, Wu Y, Wang W, Hu J, Bodily P, Tian L, Hakonarson H, Johnson WE, Wei Z, Wang K, Lyon GJ
Low concordance of multiple variant-calling pipelines: practical implications for exome and genome sequencing.
Genome Med 5: 28 (2013)
PM ID: 23537139 PMC3706896
355: Gao F, Wei Z, An W, Wang K, Lu W
The interactomes of POU5F1 and SOX2 enhancers in human embryonic stem cells.
Sci Rep 3: 1588 (2013)
PM ID: 23549118 PMC4070749
356: Rhie SK, Coetzee SG, Noushmehr H, Yan C, Kim JM, Haiman CA, Coetzee GA
Comprehensive functional annotation of seventy-one breast cancer risk Loci.
PLoS One 8: e63925 (2013)
PM ID: 23717510 PMC3661550
357: Liu SV, Fabbri M, Gitlitz BJ, Laird-Offringa IA
Epigenetic therapy in lung cancer.
Front Oncol 3: 135 (2013)
PM ID: 23755372 PMC3667274
358: Li A, Chan B, Felix JC, Xing Y, Li M, Brody SL, Borok Z, Li C, Minoo P
Tissue-dependent consequences of Apc inactivation on proliferation and differentiation of ciliated cell progenitors via Wnt and notch signaling.
PLoS One 8: e62215 (2013)
PM ID: 23646120 PMC3639955
359: Li A, Chan B, Felix JC, Xing Y, Li M, Brody SL, Zhang Y, Holtzman MJ, Borok Z, Li C, Minoo P
Correction: Tissue-Dependent Consequences of Apc Inactivation on Proliferation and Differentiation of Ciliated Cell Progenitors via Wnt and Notch Signaling.
PLoS One 8: (2013)
PM ID: 23750190
360: Chihara Y, Kanai Y, Fujimoto H, Sugano K, Kawashima K, Liang G, Jones PA, Fujimoto K, Kuniyasu H, Hirao Y
Diagnostic markers of urothelial cancer based on DNA methylation analysis.
BMC Cancer 13: 275 (2013)
PM ID: 23735005 PMC3691617
361: Wang R, Hsu HK, Blattler A, Wang Y, Lan X, Wang Y, Hsu PY, Leu YW, Huang TH, Farnham PJ, Jin VX
LOcating non-unique matched tags (LONUT) to improve the detection of the enriched regions for ChIP-seq data.
PLoS One 8: e67788 (2013)
PM ID: 23825685 PMC3692479
362: Wang K, Kim C, Bradfield J, Guo Y, Toskala E, Otieno FG, Hou C, Thomas K, Cardinale C, Lyon GJ, Golhar R, Hakonarson H
Whole-genome DNA/RNA sequencing identifies truncating mutations in RBCK1 in a novel Mendelian disease with neuromuscular and cardiac involvement.
Genome Med 5: 67 (2013)
PM ID: 23889995 PMC3971341
363: Kim H, Wu J, Ye S, Tai CI, Zhou X, Yan H, Li P, Pera M, Ying QL
Modulation of β-catenin function maintains mouse epiblast stem cell and human embryonic stem cell self-renewal.
Nat Commun 4: 2403 (2013)
PM ID: 23985566
364: Kim K, Punj V, Choi J, Heo K, Kim JM, Laird PW, An W
Gene dysregulation by histone variant H2A.Z in bladder cancer.
Epigenetics Chromatin 6: 34 (2013)
PM ID: 24279307 PMC3853418
365: Kim JM, Heo K, Choi J, Kim K, An W
The histone variant MacroH2A regulates Ca(2+) influx through TRPC3 and TRPC6 channels.
Oncogenesis 2: e77 (2013)
PM ID: 24165580 PMC3816217
366: St Pourcain B, Whitehouse AJ, Ang WQ, Warrington NM, Glessner JT, Wang K, Timpson NJ, Evans DM, Kemp JP, Ring SM, McArdle WL, Golding J, Hakonarson H, Pennell CE, Smith GD
Common variation contributes to the genetic architecture of social communication traits.
Mol Autism 4: 34 (2013)
PM ID: 24047820 PMC3853437
367: Zhang Y, Tseng CC, Tsai YL, Fu X, Schiff R, Lee AS
Cancer cells resistant to therapy promote cell surface relocalization of GRP78 which complexes with PI3K and enhances PI(3,4,5)P3 production.
PLoS One 8: e80071 (2013)
PM ID: 24244613 PMC3823711
368: Blattler A, Yao L, Wang Y, Ye Z, Jin VX, Farnham PJ
ZBTB33 binds unmethylated regions of the genome associated with actively expressed genes.
Epigenetics Chromatin 6: 13 (2013)
PM ID: 23693142 PMC3663758
369: Hazelett DJ, Coetzee SG, Coetzee GA
A rare variant, which destroys a FoxA1 site at 8q24, is associated with prostate cancer risk.
Cell Cycle 12: 379-80 (2013)
PM ID: 23255135 PMC3575466
370: Lei MX, Chuong CM, Widelitz RB
Tuning Wnt signals for more or fewer hairs.
J Invest Dermatol 133: 7-9 (2013)
PM ID: 23299447 PMC3686512 NIHMS465506
371: Deliard S, Panossian S, Mentch FD, Kim CE, Hou C, Frackelton EC, Bradfield JP, Glessner JT, Zhang H, Wang K, Sleiman PM, Chiavacci RM, Berkowitz RI, Hakonarson H, Zhao J, Grant SF
The missense variation landscape of FTO, MC4R, and TMEM18 in obese children of African Ancestry.
Obesity (Silver Spring) 21: 159-63 (2013)
PM ID: 23505181 PMC3605748 NIHMS417070
372: Kandyba E, Leung Y, Chen YB, Widelitz R, Chuong CM, Kobielak K
Competitive balance of intrabulge BMP/Wnt signaling reveals a robust gene network ruling stem cell homeostasis and cyclic activation.
Proc Natl Acad Sci U S A 110: 1351-6 (2013)
PM ID: 23292934 PMC3557042
373: Luo B, Lee AS
The critical roles of endoplasmic reticulum chaperones and unfolded protein response in tumorigenesis and anticancer therapies.
Oncogene 32: 805-18 (2013)
PM ID: 22508478 PMC3819728 NIHMS508600
374: Davis GB, Peric M, Chan LS, Wong AK, Sener SF
Identifying risk factors for surgical site infections in mastectomy patients using the National Surgical Quality Improvement Program database.
Am J Surg 205: 194-9 (2013)
PM ID: 22944390
375: Hong J, He H, Bui P, Ryba-White B, Rumi MA, Soares MJ, Dutta D, Paul S, Kawamata M, Ochiya T, Ying QL, Rajanahalli P, Weiss ML
A focused microarray for screening rat embryonic stem cell lines.
Stem Cells Dev 22: 431-43 (2013)
PM ID: 22889370 PMC3549623
376: Liu Y, Fang Y, Zhou Y, Zandi E, Lee CL, Joo KI, Wang P
Site-specific modification of adeno-associated viruses via a genetically engineered aldehyde tag.
Small 9: 421-9 (2013)
PM ID: 23038676
377: Aragaki AK, Baron JA, Berndt SI, Bezieau S, Brenner H, Butterbach K, Caan BJ, Carlson CS, Casey G, Chan AT, Chang-Claude J, Chanock SJ, Chen LS, Coetzee GA, Coetzee SG, Conti DV, Curtis K, Duggan D, Edwards TL, Fuchs CS, Gallinger S, Giovannucci EL, Gogarten SM, Haile RW, Harrison TA, Hayes RB, Hoffmeister M, Hopper JL, Hsu L, Hudson TJ, Hunter DJ, Hutter CM, Jackson RD, Jenkins MA, Jiao S, Kooperberg C, Küry S, Lacroix AZ, Laurie CC, Laurie CA, Le Marchand L, Lemire M, Levine D, Lindor NM, Liu Y, Ma J, Makar KW, Newcomb PA, Peters U, Potter JD, Prentice RL, Qu C, Rohan T, Schoen RE, Thibodeau SN, Ulrich CM, Vijayaraghavan R, Weir B, White E, Zanke BW, Jia WH, Zhang B, Matsuo K, Shin A, Xiang YB, Jee SH, Kim DH, Ren Z, Cai Q, Long J, Shi J, Wen W, Yang G, Delahanty RJ, Genetics and Epidemiology of Colorectal Cancer Consortium (GECCO) , Colon Cancer Family Registry (CCFR) , Ji BT, Pan ZZ, Matsuda F, Gao YT, Oh JH, Ahn YO, Park EJ, Li HL, Park JW, Jo J, Jeong JY, Hosono S, Casey G, Peters U, Shu XO, Zeng YX, Zheng W
Genome-wide association analyses in East Asians identify new susceptibility loci for colorectal cancer.
Nat Genet 45: 191-6 (2013)
PM ID: 23263487 PMC3679924 NIHMS474676
378: Matsuo K, Gray MJ, Yang DY, Srivastava SA, Tripathi PB, Sonoda LA, Yoo EJ, Dubeau L, Lee AS, Lin YG
The endoplasmic reticulum stress marker, glucose-regulated protein-78 (GRP78) in visceral adipocytes predicts endometrial cancer progression and patient survival.
Gynecol Oncol 128: 552-9 (2013)
PM ID: 23200913
379: Zhu G, Ye R, Jung DY, Barron E, Friedline RH, Benoit VM, Hinton DR, Kim JK, Lee AS
GRP78 plays an essential role in adipogenesis and postnatal growth in mice.
FASEB J 27: 955-64 (2013)
PM ID: 23180827 PMC3574283
380: Donnelly P, Bell J, Bentley D, McVean G, Ratcliffe P, Taylor J, Wilkie A, Donnelly P, Broxholme J, Buck D, Cazier JB, Cornall R, Gregory L, Knight J, Lunter G, McVean G, Taylor J, Tomlinson I, Wilkie A, Buck D, Allan C, Attar M, Green A, Gregory L, Humphray S, Kingsbury Z, Lamble S, Lonie L, Pagnamenta A, Piazza P, Polanco G, Trebes A, McVean G, Donnelly P, Cazier JB, Broxholme J, Copley R, Fiddy S, Grocock R, Hatton E, Holmes C, Hughes L, Humburg P, Kanapin A, Lise S, Lunter G, Martin H, Murray L, McCarthy D, Rimmer A, Sahgal N, Wright B, Yau C, Sharma VP, Fenwick AL, Brockop MS, McGowan SJ, Goos JA, Hoogeboom AJ, Brady AF, Jeelani NO, Lynch SA, Mulliken JB, Murray DJ, Phipps JM, Sweeney E, Tomkins SE, Wilson LC, Bennett S, Cornall RJ, Broxholme J, Kanapin A, 500 Whole-Genome Sequences (WGS500) Consortium , Johnson D, Wall SA, van der Spek PJ, Mathijssen IM, Maxson RE, Twigg SR, Wilkie AO
Mutations in TCF12, encoding a basic helix-loop-helix partner of TWIST1, are a frequent cause of coronal craniosynostosis.
Nat Genet 45: 304-7 (2013)
PM ID: 23354436 PMC3647333
381: Pohl A, El-Khoueiry A, Yang D, Zhang W, Lurje G, Ning Y, Winder T, Hu-Lieskoven S, Iqbal S, Danenberg KD, Kahn M, Teo JL, Shriki J, Stebbing J, Lenz HJ
Pharmacogenetic profiling of CD133 is associated with response rate (RR) and progression-free survival (PFS) in patients with metastatic colorectal cancer (mCRC), treated with bevacizumab-based chemotherapy.
Pharmacogenomics J 13: 173-80 (2013)
PM ID: 22231565 PMC3326190 NIHMS337191
382: Pelikan RC, Iwata J, Suzuki A, Chai Y, Hacia JG
Identification of candidate downstream targets of TGFβ signaling during palate development by genome-wide transcript profiling.
J Cell Biochem 114: 796-807 (2013)
PM ID: 23060211 PMC3777336 NIHMS470529
383: Peters U, Jiao S, Schumacher FR, Hutter CM, Aragaki AK, Baron JA, Berndt SI, Bézieau S, Brenner H, Butterbach K, Caan BJ, Campbell PT, Carlson CS, Casey G, Chan AT, Chang-Claude J, Chanock SJ, Chen LS, Coetzee GA, Coetzee SG, Conti DV, Curtis KR, Duggan D, Edwards T, Fuchs CS, Gallinger S, Giovannucci EL, Gogarten SM, Gruber SB, Haile RW, Harrison TA, Hayes RB, Henderson BE, Hoffmeister M, Hopper JL, Hudson TJ, Hunter DJ, Jackson RD, Jee SH, Jenkins MA, Jia WH, Kolonel LN, Kooperberg C, Küry S, Lacroix AZ, Laurie CC, Laurie CA, Le Marchand L, Lemire M, Levine D, Lindor NM, Liu Y, Ma J, Makar KW, Matsuo K, Newcomb PA, Potter JD, Prentice RL, Qu C, Rohan T, Rosse SA, Schoen RE, Seminara D, Shrubsole M, Shu XO, Slattery ML, Taverna D, Thibodeau SN, Ulrich CM, White E, Xiang Y, Zanke BW, Zeng YX, Zhang B, Zheng W, Hsu L, Colon Cancer Family Registry and the Genetics and Epidemiology of Colorectal Cancer Consortium
Identification of Genetic Susceptibility Loci for Colorectal Tumors in a Genome-Wide Meta-analysis.
Gastroenterology 144: 799-807.e24 (2013)
PM ID: 23266556 PMC3636812 NIHMS431479
384: Pandiyan K, You JS, Yang X, Dai C, Zhou XJ, Baylin SB, Jones PA, Liang G
Functional DNA demethylation is accompanied by chromatin accessibility.
Nucleic Acids Res 41: 3973-85 (2013)
PM ID: 23408854 PMC3627572
385: Patil AA, Ouellette AJ, Lu W, Zhang G
Rattusin, an intestinal α-defensin-related peptide in rats with a unique cysteine spacing pattern and salt-insensitive antibacterial activities.
Antimicrob Agents Chemother 57: 1823-31 (2013)
PM ID: 23380721 PMC3623328
386: Hoang T, Fenne IS, Madsen A, Bozickovic O, Johannessen M, Bergsvåg M, Lien EA, Stallcup MR, Sagen JV, Moens U, Mellgren G
cAMP response element-binding protein interacts with and stimulates the proteasomal degradation of the nuclear receptor coactivator GRIP1.
Endocrinology 154: 1513-27 (2013)
PM ID: 23462962
387: Triche TJ, Weisenberger DJ, Van Den Berg D, Laird PW, Siegmund KD
Low-level processing of Illumina Infinium DNA Methylation BeadArrays.
Nucleic Acids Res 41: e90 (2013)
PM ID: 23476028 PMC3627582
388: Heijmans J, van Lidth de Jeude JF, Koo BK, Rosekrans SL, Wielenga MC, van de Wetering M, Ferrante M, Lee AS, Onderwater JJ, Paton JC, Paton AW, Mommaas AM, Kodach LL, Hardwick JC, Hommes DW, Clevers H, Muncan V, van den Brink GR
ER stress causes rapid loss of intestinal epithelial stemness through activation of the unfolded protein response.
Cell Rep 3: 1128-39 (2013)
PM ID: 23545496
389: You JS, De Carvalho DD, Dai C, Liu M, Pandiyan K, Zhou XJ, Liang G, Jones PA
SNF5 is an essential executor of epigenetic regulation during differentiation.
PLoS Genet 9: e1003459 (2013)
PM ID: 23637628 PMC3636213
390: Garcia-Closas M, Couch FJ, Lindstrom S, Michailidou K, Schmidt MK, Brook MN, Orr N, Rhie SK, Riboli E, Feigelson HS, Le Marchand L, Buring JE, Eccles D, Miron P, Fasching PA, Brauch H, Chang-Claude J, Carpenter J, Godwin AK, Nevanlinna H, Giles GG, Cox A, Hopper JL, Bolla MK, Wang Q, Dennis J, Dicks E, Howat WJ, Schoof N, Bojesen SE, Lambrechts D, Broeks A, Andrulis IL, Guénel P, Burwinkel B, Sawyer EJ, Hollestelle A, Fletcher O, Winqvist R, Brenner H, Mannermaa A, Hamann U, Meindl A, Lindblom A, Zheng W, Devillee P, Goldberg MS, Lubinski J, Kristensen V, Swerdlow A, Anton-Culver H, Dörk T, Muir K, Matsuo K, Wu AH, Radice P, Teo SH, Shu XO, Blot W, Kang D, Hartman M, Sangrajrang S, Shen CY, Southey MC, Park DJ, Hammet F, Stone J, Veer LJ, Rutgers EJ, Lophatananon A, Stewart-Brown S, Siriwanarangsan P, Peto J, Schrauder MG, Ekici AB, Beckmann MW, Dos Santos Silva I, Johnson N, Warren H, Tomlinson I, Kerin MJ, Miller N, Marme F, Schneeweiss A, Sohn C, Truong T, Laurent-Puig P, Kerbrat P, Nordestgaard BG, Nielsen SF, Flyger H, Milne RL, Perez JI, Menéndez P, Müller H, Arndt V, Stegmaier C, Lichtner P, Lochmann M, Justenhoven C, Ko YD, Gene ENvironmental Interaction and breast CAncer (GENICA) Network , Muranen TA, Aittomäki K, Blomqvist C, Greco D, Heikkinen T, Ito H, Iwata H, Yatabe Y, Antonenkova NN, Margolin S, Kataja V, Kosma VM, Hartikainen JM, Balleine R, kConFab Investigators , Tseng CC, Berg DV, Stram DO, Neven P, Dieudonné AS, Leunen K, Rudolph A, Nickels S, Flesch-Janys D, Peterlongo P, Peissel B, Bernard L, Olson JE, Wang X, Stevens K, Severi G, Baglietto L, McLean C, Coetzee GA, Feng Y, Henderson BE, Schumacher F, Bogdanova NV, Labrèche F, Dumont M, Yip CH, Taib NA, Cheng CY, Shrubsole M, Long J, Pylkäs K, Jukkola-Vuorinen A, Kauppila S, Knight JA, Glendon G, Mulligan AM, Tollenaar RA, Seynaeve CM, Kriege M, Hooning MJ, van den Ouweland AM, van Deurzen CH, Lu W, Gao YT, Cai H, Balasubramanian SP, Cross SS, Reed MW, Signorello L, Cai Q, Shah M, Miao H, Chan CW, Chia KS, Jakubowska A, Jaworska K, Durda K, Hsiung CN, Wu PE, Yu JC, Ashworth A, Jones M, Tessier DC, González-Neira A, Pita G, Alonso MR, Vincent D, Bacot F, Ambrosone CB, Bandera EV, John EM, Chen GK, Hu JJ, Rodriguez-Gil JL, Bernstein L, Press MF, Ziegler RG, Millikan RM, Deming-Halverson SL, Nyante S, Ingles SA, Waisfisz Q, Tsimiklis H, Makalic E, Schmidt D, Bui M, Gibson L, Müller-Myhsok B, Schmutzler RK, Hein R, Dahmen N, Beckmann L, Aaltonen K, Czene K, Irwanto A, Liu J, Turnbull C, Familial Breast Cancer Study (FBCS) , Rahman N, Meijers-Heijboer H, Uitterlinden AG, Rivadeneira F, Australian Breast Cancer Tissue Bank (ABCTB) Investigators , Olswold C, Slager S, Pilarski R, Ademuyiwa F, Konstantopoulou I, Martin NG, Montgomery GW, Slamon DJ, Rauh C, Lux MP, Jud SM, Bruning T, Weaver J, Sharma P, Pathak H, Tapper W, Gerty S, Durcan L, Trichopoulos D, Tumino R, Peeters PH, Kaaks R, Campa D, Canzian F, Weiderpass E, Johansson M, Khaw KT, Travis R, Clavel-Chapelon F, Kolonel LN, Chen C, Beck A, Hankinson SE, Berg CD, Hoover RN, Lissowska J, Figueroa JD, Chasman DI, Gaudet MM, Diver WR, Willett WC, Hunter DJ, Simard J, Benitez J, Dunning AM, Sherman ME, Chenevix-Trench G, Chanock SJ, Hall P, Pharoah PD, Vachon C, Easton DF, Haiman CA, Kraft P
Genome-wide association studies identify four ER negative-specific breast cancer risk loci.
Nat Genet 45: 392-8, 398e1-2 (2013)
PM ID: 23535733 PMC3771695 NIHMS479348
391: Pharoah PD, Tsai YY, Ramus SJ, Phelan CM, Goode EL, Lawrenson K, Buckley M, Fridley BL, Tyrer JP, Shen H, Weber R, Karevan R, Larson MC, Song H, Tessier DC, Bacot F, Vincent D, Cunningham JM, Dennis J, Dicks E, Australian Cancer Study , Australian Ovarian Cancer Study Group , Aben KK, Anton-Culver H, Antonenkova N, Armasu SM, Baglietto L, Bandera EV, Beckmann MW, Birrer MJ, Bloom G, Bogdanova N, Brenton JD, Brinton LA, Brooks-Wilson A, Brown R, Butzow R, Campbell I, Carney ME, Carvalho RS, Chang-Claude J, Chen YA, Chen Z, Chow WH, Cicek MS, Coetzee G, Cook LS, Cramer DW, Cybulski C, Dansonka-Mieszkowska A, Despierre E, Doherty JA, Dörk T, du Bois A, Dürst M, Eccles D, Edwards R, Ekici AB, Fasching PA, Fenstermacher D, Flanagan J, Gao YT, Garcia-Closas M, Gentry-Maharaj A, Giles G, Gjyshi A, Gore M, Gronwald J, Guo Q, Halle MK, Harter P, Hein A, Heitz F, Hillemanns P, Hoatlin M, Høgdall E, Høgdall CK, Hosono S, Jakubowska A, Jensen A, Kalli KR, Karlan BY, Kelemen LE, Kiemeney LA, Kjaer SK, Konecny GE, Krakstad C, Kupryjanczyk J, Lambrechts D, Lambrechts S, Le ND, Lee N, Lee J, Leminen A, Lim BK, Lissowska J, Lubinski J, Lundvall L, Lurie G, Massuger LF, Matsuo K, McGuire V, McLaughlin JR, Menon U, Modugno F, Moysich KB, Nakanishi T, Narod SA, Ness RB, Nevanlinna H, Nickels S, Noushmehr H, Odunsi K, Olson S, Orlow I, Paul J, Pejovic T, Pelttari LM, Permuth-Wey J, Pike MC, Poole EM, Qu X, Risch HA, Rodriguez-Rodriguez L, Rossing MA, Rudolph A, Runnebaum I, Rzepecka IK, Salvesen HB, Schwaab I, Severi G, Shen H, Shridhar V, Shu XO, Sieh W, Southey MC, Spellman P, Tajima K, Teo SH, Terry KL, Thompson PJ, Timorek A, Tworoger SS, van Altena AM, Van Den Berg D, Vergote I, Vierkant RA, Vitonis AF, Wang-Gohrke S, Wentzensen N, Whittemore AS, Wik E, Winterhoff B, Woo YL, Wu AH, Yang HP, Zheng W, Ziogas A, Zulkifli F, Goodman MT, Hall P, Easton DF, Pearce CL, Berchuck A, Chenevix-Trench G, Iversen E, Monteiro AN, Gayther SA, Schildkraut JM, Sellers TA
GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer.
Nat Genet 45: 362-70, 370e1-2 (2013)
PM ID: 23535730 PMC3693183 NIHMS474884
392: Li A, Chen M, Jiang TX, Wu P, Nie Q, Widelitz R, Chuong CM
Shaping organs by a wingless-int/Notch/nonmuscle myosin module which orients feather bud elongation.
Proc Natl Acad Sci U S A 110: E1452-61 (2013)
PM ID: 23576731 PMC3631647
393: Heo K, Kim JS, Kim K, Kim H, Choi J, Yang K, An W
Cell-penetrating H4 tail peptides potentiate p53-mediated transactivation via inhibition of G9a and HDAC1.
Oncogene 32: 2510-20 (2013)
PM ID: 22751130
394: Bateman LA, Zaro BW, Chuh KN, Pratt MR
N-Propargyloxycarbamate monosaccharides as metabolic chemical reporters of carbohydrate salvage pathways and protein glycosylation.
Chem Commun (Camb) 49: 4328-30 (2013)
PM ID: 23235740
395: Loo LW, Tiirikainen M, Cheng I, Lum-Jones A, Seifried A, Church JM, Gryfe R, Weisenberger DJ, Lindor NM, Gallinger S, Haile RW, Duggan DJ, Thibodeau SN, Casey G, Le Marchand L
Integrated analysis of genome-wide copy number alterations and gene expression in microsatellite stable, CpG island methylator phenotype-negative colon cancer.
Genes Chromosomes Cancer 52: 450-66 (2013)
PM ID: 23341073 PMC4019504 NIHMS571110
396: Balasubramaniam S, Comstock CE, Ertel A, Jeong KW, Stallcup MR, Addya S, McCue PA, Ostrander WF, Augello MA, Knudsen KE
Aberrant BAF57 signaling facilitates prometastatic phenotypes.
Clin Cancer Res 19: 2657-67 (2013)
PM ID: 23493350 PMC3655134 NIHMS455459
397: Wu P, Wu X, Jiang TX, Elsey RM, Temple BL, Divers SJ, Glenn TC, Yuan K, Chen MH, Widelitz RB, Chuong CM
Specialized stem cell niche enables repetitive renewal of alligator teeth.
Proc Natl Acad Sci U S A 110: E2009-18 (2013)
PM ID: 23671090 PMC3670376
398: Getz G, Gabriel SB, Cibulskis K, Lander E, Sivachenko A, Sougnez C, Lawrence M, Kandoth C, Dooling D, Fulton R, Fulton L, Kalicki-Veizer J, McLellan MD, O'Laughlin M, Schmidt H, Wilson RK, Ye K, Ding L, Mardis ER, Ally A, Balasundaram M, Birol I, Butterfield YS, Carlsen R, Carter C, Chu A, Chuah E, Chuah HJ, Dhalla N, Guin R, Hirst C, Holt RA, Jones SJ, Lee D, Li HI, Marra MA, Mayo M, Moore RA, Mungall AJ, Plettner P, Schein JE, Sipahimalani P, Tam A, Varhol RJ, Robertson A, Cherniack AD, Pashtan I, Saksena G, Onofrio RC, Schumacher SE, Tabak B, Carter SL, Hernandez B, Gentry J, Salvesen HB, Ardlie K, Getz G, Winckler W, Beroukhim R, Gabriel SB, Meyerson M, Hadjipanayis A, Lee S, Mahadeshwar HS, Park P, Protopopov A, Ren X, Seth S, Song X, Tang J, Xi R, Yang L, Zeng D, Kucherlapati R, Chin L, Zhang J, Auman T, Balu S, Bodenheimer T, Buda E, Hayes D, Hoyle AP, Jefferys SR, Jones CD, Meng S, Mieczkowski PA, Mose LE, Parker JS, Perou CM, Roach J, Shi Y, Simons JV, Soloway MG, Tan D, Topal MD, Waring S, Wu J, Hoadley KA, Baylin SB, Bootwalla MS, Lai PH, Triche TJ, Van Den Berg DJ, Weisenberger DJ, Laird PW, Shen H, Chin L, Zhang J, Getz G, Cho J, DiCara D, Frazer S, Heiman D, Jing R, Lin P, Mallard W, Stojanov P, Voet D, Zhang H, Zou L, Noble M, Lawrence M, Reynolds SM, Shmulevich I, Aksoy B, Antipin Y, Ciriello G, Dresdner G, Gao J, Gross B, Jacobsen A, Ladanyi M, Reva B, Sander C, Sinha R, Sumer S, Taylor BS, Cerami E, Weinhold N, Schultz N, Shen R, Benz S, Goldstein T, Haussler D, Ng S, Szeto C, Stuart J, Benz CC, Yau C, Zhang W, Annala M, Broom BM, Casasent TD, Ju Z, Liang H, Liu G, Lu Y, Unruh AK, Wakefield C, Weinstein JN, Zhang N, Liu Y, Broaddus R, Akbani R, Mills GB, Adams C, Barr T, Black AD, Bowen J, Deardurff J, Frick J, Gastier-Foster JM, Grossman T, Harper HA, Hart-Kothari M, Helsel C, Hobensack A, Kuck H, Kneile K, Leraas KM, Lichtenberg TM, McAllister C, Pyatt RE, Ramirez NC, Tabler TR, Vanhoose N, White P, Wise L, Zmuda E, Barnabas N, Berry-Green C, Blanc V, Boice L, Button M, Farkas A, Green A, MacKenzie J, Nicholson D, Kalloger SE, Gilks CB, Karlan BY, Lester J, Orsulic S, Borowsky M, Cadungog M, Czerwinski C, Huelsenbeck-Dill L, Iacocca M, Petrelli N, Rabeno B, Witkin G, Nemirovich-Danchenko E, Potapova O, Rotin D, Berchuck A, Birrer M, DiSaia P, Monovich L, Curley E, Gardner J, Mallery D, Penny R, Dowdy SC, Winterhoff B, Dao L, Gostout B, Meuter A, Teoman A, Dao F, Olvera N, Bogomolniy F, Garg K, Soslow RA, Levine DA, Abramov M, Bartlett JM, Kodeeswaran S, Parfitt J, Moiseenko F, Clarke BA, Goodman MT, Carney ME, Matsuno RK, Fisher J, Huang M, Rathmell W, Thorne L, Van Le L, Dhir R, Edwards R, Elishaev E, Zorn K, Broaddus R, Goodfellow PJ, Mutch D, Schultz N, Liu Y, Akbani R, Cherniack AD, Cerami E, Weinhold N, Shen H, Hoadley KA, Kahn AB, Bell DW, Pollock PM, Wang C, Wheeler DA, Shinbrot E, Karlan BY, Berchuck A, Dowdy SC, Winterhoff B, Goodman MT, Robertson A, Beroukhim R, Pashtan I, Salvesen HB, Laird PW, Noble M, Stuart J, Ding L, Kandoth C, Gilks C, Soslow RA, Goodfellow PJ, Mutch D, Broaddus R, Zhang W, Mills GB, Kucherlapati R, Mardis ER, Levine DA, Ayala B, Chu AL, Jensen MA, Kothiyal P, Pihl TD, Pontius J, Pot DA, Snyder EE, Srinivasan D, Kahn AB, Shaw KR, Sheth M, Davidsen T, Eley G, Ferguson ML, Demchok JA, Yang L, Guyer MS, Ozenberger BA, Sofia HJ, Cancer Genome Atlas Research Network , Kandoth C, Schultz N, Cherniack AD, Akbani R, Liu Y, Shen H, Robertson AG, Pashtan I, Shen R, Benz CC, Yau C, Laird PW, Ding L, Zhang W, Mills GB, Kucherlapati R, Mardis ER, Levine DA
Integrated genomic characterization of endometrial carcinoma.
Nature 497: 67-73 (2013)
PM ID: 23636398 PMC3704730 NIHMS458933
399: Ley TJ, Miller C, Ding L, Raphael BJ, Mungall AJ, Robertson A, Hoadley K, Triche TJ, Laird PW, Baty JD, Fulton LL, Fulton R, Heath SE, Kalicki-Veizer J, Kandoth C, Klco JM, Koboldt DC, Kanchi KL, Kulkarni S, Lamprecht TL, Larson DE, Lin L, Lu C, McLellan MD, McMichael JF, Payton J, Schmidt H, Spencer DH, Tomasson MH, Wallis JW, Wartman LD, Watson MA, Welch J, Wendl MC, Ally A, Balasundaram M, Birol I, Butterfield Y, Chiu R, Chu A, Chuah E, Chun HJ, Corbett R, Dhalla N, Guin R, He A, Hirst C, Hirst M, Holt RA, Jones S, Karsan A, Lee D, Li HI, Marra MA, Mayo M, Moore RA, Mungall K, Parker J, Pleasance E, Plettner P, Schein J, Stoll D, Swanson L, Tam A, Thiessen N, Varhol R, Wye N, Zhao Y, Gabriel S, Getz G, Sougnez C, Zou L, Leiserson MD, Vandin F, Wu HT, Applebaum F, Baylin SB, Akbani R, Broom BM, Chen K, Motter TC, Nguyen K, Weinstein JN, Zhang N, Ferguson ML, Adams C, Black A, Bowen J, Gastier-Foster J, Grossman T, Lichtenberg T, Wise L, Davidsen T, Demchok JA, Shaw KR, Sheth M, Sofia HJ, Yang L, Downing JR, Eley G, Alonso S, Ayala B, Baboud J, Backus M, Barletta SP, Berton DL, Chu AL, Girshik S, Jensen MA, Kahn A, Kothiyal P, Nicholls MC, Pihl TD, Pot DA, Raman R, Sanbhadti RN, Snyder EE, Srinivasan D, Walton J, Wan Y, Wang Z, Issa JP, Le Beau M, Carroll M, Kantarjian H, Kornblau S, Bootwalla MS, Lai PH, Shen H, Van Den Berg DJ, Weisenberger DJ, Link DC, Walter MJ, Ozenberger BA, Mardis ER, Westervelt P, Graubert TA, Dipersio JF, Wilson RK, Cancer Genome Atlas Research Network
Genomic and epigenomic landscapes of adult de novo acute myeloid leukemia.
N Engl J Med 368: 2059-74 (2013)
PM ID: 23634996 PMC3767041 NIHMS491910
400: Monda KL, Chen GK, Taylor KC, Palmer C, Edwards TL, Lange LA, Ng MC, Adeyemo AA, Allison MA, Bielak LF, Chen G, Graff M, Irvin MR, Rhie SK, Li G, Liu Y, Liu Y, Lu Y, Nalls MA, Sun YV, Wojczynski MK, Yanek LR, Aldrich MC, Ademola A, Amos CI, Bandera EV, Bock CH, Britton A, Broeckel U, Cai Q, Caporaso NE, Carlson CS, Carpten J, Casey G, Chen WM, Chen F, Chen YD, Chiang CW, Coetzee GA, Demerath E, Deming-Halverson SL, Driver RW, Dubbert P, Feitosa MF, Feng Y, Freedman BI, Gillanders EM, Gottesman O, Guo X, Haritunians T, Harris T, Harris CC, Hennis AJ, Hernandez DG, McNeill LH, Howard TD, Howard BV, Howard VJ, Johnson KC, Kang SJ, Keating BJ, Kolb S, Kuller LH, Kutlar A, Langefeld CD, Lettre G, Lohman K, Lotay V, Lyon H, Manson JE, Maixner W, Meng YA, Monroe KR, Morhason-Bello I, Murphy AB, Mychaleckyj JC, Nadukuru R, Nathanson KL, Nayak U, N'Diaye A, Nemesure B, Wu SY, Leske MC, Neslund-Dudas C, Neuhouser M, Nyante S, Ochs-Balcom H, Ogunniyi A, Ogundiran TO, Ojengbede O, Olopade OI, Palmer JR, Ruiz-Narvaez EA, Palmer ND, Press MF, Rampersaud E, Rasmussen-Torvik LJ, Rodriguez-Gil JL, Salako B, Schadt EE, Schwartz AG, Shriner DA, Siscovick D, Smith SB, Wassertheil-Smoller S, Speliotes EK, Spitz MR, Sucheston L, Taylor H, Tayo BO, Tucker MA, Van Den Berg DJ, Edwards DR, Wang Z, Wiencke JK, Winkler TW, Witte JS, Wrensch M, Wu X, Yang JJ, Levin AM, Young TR, Zakai NA, Cushman M, Zanetti KA, Zhao JH, Zhao W, Zheng Y, Zhou J, Ziegler RG, Zmuda JM, Fernandes JK, Gilkeson GS, Kamen DL, Hunt KJ, Spruill IJ, Ambrosone CB, Ambs S, Arnett DK, Atwood L, Becker DM, Berndt SI, Bernstein L, Blot WJ, Borecki IB, Bottinger EP, Bowden DW, Burke G, Chanock SJ, Cooper RS, Ding J, Duggan D, Evans MK, Fox C, Garvey WT, Bradfield JP, Hakonarson H, Grant SF, Hsing A, Chu L, Hu JJ, Huo D, Ingles SA, John EM, Jordan JM, Kabagambe EK, Kardia SL, Kittles RA, Goodman PJ, Klein EA, Kolonel LN, Le Marchand L, Liu S, McKnight B, Millikan RC, Mosley TH, Padhukasahasram B, Williams LK, Patel SR, Peters U, Pettaway CA, Peyser PA, Psaty BM, Redline S, Rotimi CN, Rybicki BA, Sale MM, Schreiner PJ, Signorello LB, Singleton AB, Stanford JL, Strom SS, Thun MJ, Vitolins M, Zheng W, Moore JH, Williams SM, Ketkar S, Zhu X, Zonderman AB, NABEC Consortium , UKBEC Consortium , BioBank Japan Project , AGEN Consortium , Kooperberg C, Papanicolaou GJ, Henderson BE, Reiner AP, Hirschhorn JN, Loos RJ, North KE, Haiman CA
A meta-analysis identifies new loci associated with body mass index in individuals of African ancestry.
Nat Genet 45: 690-6 (2013)
PM ID: 23583978 PMC3694490 NIHMS474899
401: Lin SJ, Foley J, Jiang TX, Yeh CY, Wu P, Foley A, Yen CM, Huang YC, Cheng HC, Chen CF, Reeder B, Jee SH, Widelitz RB, Chuong CM
Topology of feather melanocyte progenitor niche allows complex pigment patterns to emerge.
Science 340: 1442-5 (2013)
PM ID: 23618762
402: Rohira AD, Chen CY, Allen JR, Johnson DL
Covalent small ubiquitin-like modifier (SUMO) modification of Maf1 protein controls RNA polymerase III-dependent transcription repression.
J Biol Chem 288: 19288-95 (2013)
PM ID: 23673667 PMC3696699
403: Li C, Li A, Xing Y, Li M, Chan B, Ouyang R, Taketo MM, Kucherlapati R, Borok Z, Minoo P
Apc deficiency alters pulmonary epithelial cell fate and inhibits Nkx2.1 via triggering TGF-beta signaling.
Dev Biol 378: 13-24 (2013)
PM ID: 23562608 PMC3838671 NIHMS463440
404: Marconett CN, Zhou B, Rieger ME, Selamat SA, Dubourd M, Fang X, Lynch SK, Stueve TR, Siegmund KD, Berman BP, Borok Z, Laird-Offringa IA
Integrated transcriptomic and epigenomic analysis of primary human lung epithelial cell differentiation.
PLoS Genet 9: e1003513 (2013)
PM ID: 23818859 PMC3688557
405: Li C, Li Y, He L, Agarwal AR, Zeng N, Cadenas E, Stiles BL
PI3K/AKT signaling regulates bioenergetics in immortalized hepatocytes.
Free Radic Biol Med 60: 29-40 (2013)
PM ID: 23376468 PMC3654039 NIHMS441394
406: Schumacher FR, Wang Z, Skotheim RI, Koster R, Chung CC, Hildebrandt MA, Kratz CP, Bakken AC, Bishop DT, Cook MB, Erickson RL, Fosså SD, Greene MH, Jacobs KB, Kanetsky PA, Kolonel LN, Loud JT, Korde LA, Le Marchand L, Lewinger JP, Lothe RA, Pike MC, Rahman N, Rubertone MV, Schwartz SM, Siegmund KD, Skinner EC, Turnbull C, Van Den Berg DJ, Wu X, Yeager M, Nathanson KL, Chanock SJ, Cortessis VK, McGlynn KA
Testicular germ cell tumor susceptibility associated with the UCK2 locus on chromosome 1q23.
Hum Mol Genet 22: 2748-53 (2013)
PM ID: 23462292 PMC3674801
407: Wei Z, Gao F, Kim S, Yang H, Lyu J, An W, Wang K, Lu W
Klf4 organizes long-range chromosomal interactions with the oct4 locus in reprogramming and pluripotency.
Cell Stem Cell 13: 36-47 (2013)
PM ID: 23747203
408: Creighton CJ, Morgan M, Gunaratne PH, Wheeler DA, Gibbs RA, Robertson A, Chu A, Beroukhim R, Cibulskis K, Signoretti S, Vandin F, Wu HT, Raphael BJ, Verhaak RG, Tamboli P, Torres-Garcia W, Akbani R, Weinstein JN, Reuter V, Hsieh JJ, Brannon A, Hakimi A, Jacobsen A, Ciriello G, Reva B, Ricketts CJ, Linehan W, Stuart JM, Rathmell W, Shen H, Laird PW, Muzny D, Davis C, Morgan M, Xi L, Chang K, Kakkar N, Treviño LR, Benton S, Reid JG, Morton D, Doddapaneni H, Han Y, Lewis L, Dinh H, Kovar C, Zhu Y, Santibanez J, Wang M, Hale W, Kalra D, Creighton CJ, Wheeler DA, Gibbs RA, Getz G, Cibulskis K, Lawrence MS, Sougnez C, Carter SL, Sivachenko A, Lichtenstein L, Stewart C, Voet D, Fisher S, Gabriel SB, Lander E, Beroukhim R, Schumacher SE, Tabak B, Saksena G, Onofrio RC, Carter SL, Cherniack AD, Gentry J, Ardlie K, Sougnez C, Getz G, Gabriel SB, Meyerson M, Robertson A, Chu A, Chun HJ, Mungall AJ, Sipahimalani P, Stoll D, Ally A, Balasundaram M, Butterfield YS, Carlsen R, Carter C, Chuah E, Coope RJ, Dhalla N, Gorski S, Guin R, Hirst C, Hirst M, Holt RA, Lebovitz C, Lee D, Li HI, Mayo M, Moore RA, Pleasance E, Plettner P, Schein JE, Shafiei A, Slobodan JR, Tam A, Thiessen N, Varhol RJ, Wye N, Zhao Y, Birol I, Jones SJ, Marra MA, Auman JT, Tan D, Jones CD, Hoadley KA, Mieczkowski PA, Mose LE, Jefferys SR, Topal MD, Liquori C, Turman YJ, Shi Y, Waring S, Buda E, Walsh J, Wu J, Bodenheimer T, Hoyle AP, Simons JV, Soloway MG, Balu S, Parker JS, Hayes D, Perou CM, Kucherlapati R, Park P, Shen H, Triche T, Weisenberger DJ, Lai PH, Bootwalla MS, Maglinte DT, Mahurkar S, Berman BP, Van Den Berg DJ, Cope L, Baylin SB, Laird PW, Creighton CJ, Wheeler DA, Getz G, Noble MS, DiCara D, Zhang H, Cho J, Heiman DI, Gehlenborg N, Voet D, Mallard W, Lin P, Frazer S, Stojanov P, Liu Y, Zhou L, Kim J, Lawrence MS, Chin L, Vandin F, Wu HT, Raphael BJ, Benz C, Yau C, Reynolds SM, Shmulevich I, Verhaak RG, Torres-Garcia W, Vegesna R, Kim H, Zhang W, Cogdell D, Jonasch E, Ding Z, Lu Y, Akbani R, Zhang N, Unruh AK, Casasent TD, Wakefield C, Tsavachidou D, Chin L, Mills GB, Weinstein JN, Jacobsen A, Brannon R, Ciriello G, Schultz N, Hakimi A, Reva B, Antipin Y, Gao J, Cerami E, Gross B, Aksoy BA, Sinha R, Weinhold N, Sumer S, Taylor BS, Shen R, Ostrovnaya I, Hsieh JJ, Berger MF, Ladanyi M, Sander C, Fei SS, Stout A, Spellman PT, Rubin DL, Liu TT, Stuart JM, Ng S, Paull EO, Carlin D, Goldstein T, Waltman P, Ellrott K, Zhu J, Haussler D, Gunaratne PH, Xiao W, Shelton C, Gardner J, Penny R, Sherman M, Mallery D, Morris S, Paulauskis J, Burnett K, Shelton T, Signoretti S, Kaelin WG, Choueiri T, Atkins MB, Penny R, Burnett K, Mallery D, Curley E, Tickoo S, Reuter V, Rathmell W, Thorne L, Boice L, Huang M, Fisher JC, Linehan WM, Vocke CD, Peterson J, Worrell R, Merino MJ, Schmidt LS, Tamboli P, Czerniak BA, Aldape KD, Wood CG, Boyd J, Weaver J, Iacocca MV, Petrelli N, Witkin G, Brown J, Czerwinski C, Huelsenbeck-Dill L, Rabeno B, Myers J, Morrison C, Bergsten J, Eckman J, Harr J, Smith C, Tucker K, Zach LA, Bshara W, Gaudioso C, Morrison C, Dhir R, Maranchie J, Nelson J, Parwani A, Potapova O, Fedosenko K, Cheville JC, Thompson RH, Signoretti S, Kaelin WG, Atkins MB, Tickoo S, Reuter V, Linehan WM, Vocke CD, Peterson J, Merino MJ, Schmidt LS, Tamboli P, Mosquera JM, Rubin MA, Blute ML, Rathmell W, Pihl T, Jensen M, Sfeir R, Kahn A, Chu A, Kothiyal P, Snyder E, Pontius J, Ayala B, Backus M, Walton J, Baboud J, Berton D, Nicholls M, Srinivasan D, Raman R, Girshik S, Kigonya P, Alonso S, Sanbhadti R, Barletta S, Pot D, Sheth M, Demchok JA, Davidsen T, Wang Z, Yang L, Tarnuzzer RW, Zhang J, Eley G, Ferguson ML, Mills Shaw KR, Guyer MS, Ozenberger BA, Sofia HJ, Cancer Genome Atlas Research Network
Comprehensive molecular characterization of clear cell renal cell carcinoma.
Nature 499: 43-9 (2013)
PM ID: 23792563 PMC3771322 NIHMS472502
409: Lai X, Zhang C, Wang J, Wang C, Lan X, Zhang C, Lei C, Chen H
mRNA expression pattern and association study with growth traits of bovine vaspin gene.
Mol Biol Rep 40: 4499-505 (2013)
PM ID: 23657594
410: Blakeley BD, Shattuck J, Coates MB, Tran E, Laird-Offringa IA, McNaughton BR
Analysis of protein-RNA complexes involving a RNA recognition motif engineered to bind hairpins with seven- and eight-nucleotide loops.
Biochemistry 52: 4745-7 (2013)
PM ID: 23806102
411: Choi IS, Yu K, Kim J, De Guzman E, Weisenberger DJ, Oghamian S, Kim HJ, Lee KH, Carroll C, Trinh BN, Kim M, Houshdaran S, Laird PW, Jones PA, Warburton D, Liang G, Koh CJ
Alterations in deoxyribonucleic acid (DNA) methylation patterns of Calca, Timp3, Mmp2, and Igf2r are associated with chronic cystitis in a cyclophosphamide-induced mouse model.
Urology 82: 253.e9-15 (2013)
PM ID: 23806407 PMC3697025 NIHMS470243
412: Xie M, Hong C, Zhang B, Lowdon RF, Xing X, Li D, Zhou X, Lee HJ, Maire CL, Ligon KL, Gascard P, Sigaroudinia M, Tlsty TD, Kadlecek T, Weiss A, O'Geen H, Farnham PJ, Madden PA, Mungall AJ, Tam A, Kamoh B, Cho S, Moore R, Hirst M, Marra MA, Costello JF, Wang T
DNA hypomethylation within specific transposable element families associates with tissue-specific enhancer landscape.
Nat Genet 45: 836-41 (2013)
PM ID: 23708189 PMC3695047 NIHMS475505
413: Schade B, Lesurf R, Sanguin-Gendreau V, Bui T, Deblois G, O'Toole SA, Millar EK, Zardawi SJ, Lopez-Knowles E, Sutherland RL, Giguère V, Kahn M, Hallett M, Muller WJ
β-Catenin signaling is a critical event in ErbB2-mediated mammary tumor progression.
Cancer Res 73: 4474-87 (2013)
PM ID: 23720052
414: Costa MA, Rommer E, Peric M, Nguyen TJ, Shahabi A, Davis GB, Vidar EN, Chan LS, Wong AK
Incidence of surgical-site infection is not affected by method of immediate breast reconstruction.
Plast Reconstr Surg 132: 20e-9e (2013)
PM ID: 23806951
415: Gray MJ, Mhawech-Fauceglia P, Yoo E, Yang W, Wu E, Lee AS, Lin YG
AKT inhibition mitigates GRP78 (glucose-regulated protein) expression and contribution to chemoresistance in endometrial cancers.
Int J Cancer 133: 21-30 (2013)
PM ID: 23280503 PMC3633665 NIHMS430163
416: Yu EJ, Kim SH, Kim MJ, Seo WY, Song KA, Kang MS, Yang CK, Stallcup MR, Kim JH
SUMOylation of ZFP282 potentiates its positive effect on estrogen signaling in breast tumorigenesis.
Oncogene 32: 4160-8 (2013)
PM ID: 22986521 PMC3874449 NIHMS540117
417: Fazlollahi F, Kim YH, Sipos A, Hamm-Alvarez SF, Borok Z, Kim KJ, Crandall ED
Nanoparticle translocation across mouse alveolar epithelial cell monolayers: species-specific mechanisms.
Nanomedicine 9: 786-94 (2013)
PM ID: 23454523 PMC3702651 NIHMS448182
418: Samadder NJ, Vierkant RA, Tillmans LS, Wang AH, Weisenberger DJ, Laird PW, Lynch CF, Anderson KE, French AJ, Haile RW, Potter JD, Slager SL, Smyrk TC, Thibodeau SN, Cerhan JR, Limburg PJ
Associations between colorectal cancer molecular markers and pathways with clinicopathologic features in older women.
Gastroenterology 145: 348-56.e1-2 (2013)
PM ID: 23665275 PMC3772766 NIHMS477695
419: Law MJ, Lee DS, Lee CS, Anglim PP, Haworth IS, Laird-Offringa IA
The role of the C-terminal helix of U1A protein in the interaction with U1hpII RNA.
Nucleic Acids Res 41: 7092-100 (2013)
PM ID: 23703211 PMC3737524
420: Wei Z, Huang D, Gao F, Chang WH, An W, Coetzee GA, Wang K, Lu W
Biological implications and regulatory mechanisms of long-range chromosomal interactions.
J Biol Chem 288: 22369-77 (2013)
PM ID: 23779110 PMC3829327
421: Gao F, Ling C, Shi L, Commins D, Zada G, Mack WJ, Wang K
Inversion-mediated gene fusions involving NAB2-STAT6 in an unusual malignant meningioma.
Br J Cancer 109: 1051-5 (2013)
PM ID: 23860521 PMC3749567
422: Yan HX, Wu HP, Zhang HL, Ashton C, Tong C, Wu J, Qian QJ, Wang HY, Ying QL
DNA damage-induced sustained p53 activation contributes to inflammation-associated hepatocarcinogenesis in rats.
Oncogene 32: 4565-71 (2013)
PM ID: 23069657 PMC3855850 NIHMS533950
423: Su SF, Chang YW, Andreu-Vieyra C, Fang JY, Yang Z, Han B, Lee AS, Liang G
miR-30d, miR-181a and miR-199a-5p cooperatively suppress the endoplasmic reticulum chaperone and signaling regulator GRP78 in cancer.
Oncogene 32: 4694-701 (2013)
PM ID: 23085757 PMC3787795
424: Zhang B, Zhou Y, Lin N, Lowdon RF, Hong C, Nagarajan RP, Cheng JB, Li D, Stevens M, Lee HJ, Xing X, Zhou J, Sundaram V, Elliott G, Gu J, Shi T, Gascard P, Sigaroudinia M, Tlsty TD, Kadlecek T, Weiss A, O'Geen H, Farnham PJ, Maire CL, Ligon KL, Madden PA, Tam A, Moore R, Hirst M, Marra MA, Zhang B, Costello JF, Wang T
Functional DNA methylation differences between tissues, cell types, and across individuals discovered using the M&M algorithm.
Genome Res 23: 1522-40 (2013)
PM ID: 23804400 PMC3759728
425: Awad S, Kunhi M, Little GH, Bai Y, An W, Bers D, Kedes L, Poizat C
Nuclear CaMKII enhances histone H3 phosphorylation and remodels chromatin during cardiac hypertrophy.
Nucleic Acids Res 41: 7656-72 (2013)
PM ID: 23804765 PMC3763528
426: Li WD, Jiao H, Wang K, Zhang CK, Glessner JT, Grant SF, Zhao H, Hakonarson H, Arlen Price R
A genome wide association study of plasma uric acid levels in obese cases and never-overweight controls.
Obesity (Silver Spring) 21: E490-4 (2013)
PM ID: 23703922 PMC3762924 NIHMS430476
427: Yan HX, Wu HP, Zhang HL, Ashton C, Tong C, Wu H, Qian QJ, Wang HY, Ying QL
p53 promotes inflammation-associated hepatocarcinogenesis by inducing HMGB1 release.
J Hepatol 59: 762-8 (2013)
PM ID: 23714159 PMC3805120 NIHMS511728
428: Thomas JP, Davis-Dao C, Lewinger JP, Siegmund KD, Hamilton AS, Daneshmand S, Skinner EC, Thomas DC, Cortessis VK
Null association between histology of first and second primary malignancies in men with bilateral testicular germ cell tumors.
Am J Epidemiol 178: 1240-5 (2013)
PM ID: 23928263 PMC3792726
429: Hattori T, Taft JM, Swist KM, Luo H, Witt H, Slattery M, Koide A, Ruthenburg AJ, Krajewski K, Strahl BD, White KP, Farnham PJ, Zhao Y, Koide S
Recombinant antibodies to histone post-translational modifications.
Nat Methods 10: 992-5 (2013)
PM ID: 23955773 PMC3828030 NIHMS510849
430: Ye S, Li P, Tong C, Ying QL
Embryonic stem cell self-renewal pathways converge on the transcription factor Tfcp2l1.
EMBO J 32: 2548-60 (2013)
PM ID: 23942238 PMC3791365
431: Bateman LA, Zaro BW, Miller SM, Pratt MR
An alkyne-aspirin chemical reporter for the detection of aspirin-dependent protein modification in living cells.
J Am Chem Soc 135: 14568-73 (2013)
PM ID: 23998633
432: Chang K, Creighton CJ, Davis C, Donehower L, Drummond J, Wheeler D, Ally A, Balasundaram M, Birol I, Butterfield SN, Chu A, Chuah E, Chun HJ, Dhalla N, Guin R, Hirst M, Hirst C, Holt RA, Jones SJ, Lee D, Li HI, Marra MA, Mayo M, Moore RA, Mungall AJ, Robertson AG, Schein JE, Sipahimalani P, Tam A, Thiessen N, Varhol RJ, Beroukhim R, Bhatt AS, Brooks AN, Cherniack AD, Freeman SS, Gabriel SB, Helman E, Jung J, Meyerson M, Ojesina AI, Pedamallu CS, Saksena G, Schumacher SE, Tabak B, Zack T, Lander ES, Bristow CA, Hadjipanayis A, Haseley P, Kucherlapati R, Lee S, Lee E, Luquette LJ, Mahadeshwar HS, Pantazi A, Parfenov M, Park PJ, Protopopov A, Ren X, Santoso N, Seidman J, Seth S, Song X, Tang J, Xi R, Xu AW, Yang L, Zeng D, Auman JT, Balu S, Buda E, Fan C, Hoadley KA, Jones CD, Meng S, Mieczkowski PA, Parker JS, Perou CM, Roach J, Shi Y, Silva GO, Tan D, Veluvolu U, Waring S, Wilkerson MD, Wu J, Zhao W, Bodenheimer T, Hayes DN, Hoyle AP, Jeffreys SR, Mose LE, Simons JV, Soloway MG, Baylin SB, Berman BP, Bootwalla MS, Danilova L, Herman JG, Hinoue T, Laird PW, Rhie SK, Shen H, Triche T, Weisenberger DJ, Carter SL, Cibulskis K, Chin L, Zhang J, Getz G, Sougnez C, Wang M, Saksena G, Carter SL, Cibulskis K, Chin L, Zhang J, Getz G, Dinh H, Doddapaneni HV, Gibbs R, Gunaratne P, Han Y, Kalra D, Kovar C, Lewis L, Morgan M, Morton D, Muzny D, Reid J, Xi L, Cho J, DiCara D, Frazer S, Gehlenborg N, Heiman DI, Kim J, Lawrence MS, Lin P, Liu Y, Noble MS, Stojanov P, Voet D, Zhang H, Zou L, Stewart C, Bernard B, Bressler R, Eakin A, Iype L, Knijnenburg T, Kramer R, Kreisberg R, Leinonen K, Lin J, Liu Y, Miller M, Reynolds SM, Rovira H, Shmulevich I, Thorsson V, Yang D, Zhang W, Amin S, Wu CJ, Wu CC, Akbani R, Aldape K, Baggerly KA, Broom B, Casasent TD, Cleland J, Creighton C, Dodda D, Edgerton M, Han L, Herbrich SM, Ju Z, Kim H, Lerner S, Li J, Liang H, Liu W, Lorenzi PL, Lu Y, Melott J, Mills GB, Nguyen L, Su X, Verhaak R, Wang W, Weinstein JN, Wong A, Yang Y, Yao J, Yao R, Yoshihara K, Yuan Y, Yung AK, Zhang N, Zheng S, Ryan M, Kane DW, Aksoy BA, Ciriello G, Dresdner G, Gao J, Gross B, Jacobsen A, Kahles A, Ladanyi M, Lee W, Lehmann KV, Miller ML, Ramirez R, Rätsch G, Reva B, Sander C, Schultz N, Senbabaoglu Y, Shen R, Sinha R, Sumer SO, Sun Y, Taylor BS, Weinhold N, Fei S, Spellman P, Benz C, Carlin D, Cline M, Craft B, Ellrott K, Goldman M, Haussler D, Ma S, Ng S, Paull E, Radenbaugh A, Salama S, Sokolov A, Stuart JM, Swatloski T, Uzunangelov V, Waltman P, Yau C, Zhu J, Hamilton SR, Getz G, Sougnez C, Abbott S, Abbott R, Dees ND, Delehaunty K, Ding L, Dooling DJ, Eldred JM, Fronick CC, Fulton R, Fulton LL, Kalicki-Veizer J, Kanchi KL, Kandoth C, Koboldt DC, Larson DE, Ley TJ, Lin L, Lu C, Magrini VJ, Mardis ER, McLellan MD, McMichael JF, Miller CA, O'Laughlin M, Pohl C, Schmidt H, Smith SM, Walker J, Wallis JW, Wendl MC, Wilson RK, Wylie T, Zhang Q, Burton R, Jensen MA, Kahn A, Pihl T, Pot D, Wan Y, Levine DA, Black AD, Bowen J, Frick J, Gastier-Foster JM, Harper HA, Helsel C, Leraas KM, Lichtenberg TM, McAllister C, Ramirez NC, Sharpe S, Wise L, Zmuda E, Chanock SJ, Davidsen T, Demchok JA, Eley G, Felau I, Ozenberger BA, Sheth M, Sofia H, Staudt L, Tarnuzzer R, Wang Z, Yang L, Zhang J, Omberg L, Margolin A, Raphael BJ, Vandin F, Wu HT, Leiserson MD, Benz SC, Vaske CJ, Noushmehr H, Knijnenburg T, Wolf D, van 't Veer L, Collisson EA, Anastassiou D, Ou Yang TH, Lopez-Bigas N, Gonzalez-Perez A, Tamborero D, Xia Z, Li W, Cho DY, Przytycka T, Hamilton M, McGuire S, Nelander S, Johansson P, Jörnsten R, Kling T, Sanchez J, Cancer Genome Atlas Research Network , Weinstein JN, Collisson EA, Mills GB, Shaw KR, Ozenberger BA, Ellrott K, Shmulevich I, Sander C, Stuart JM
The Cancer Genome Atlas Pan-Cancer analysis project.
Nat Genet 45: 1113-20 (2013)
PM ID: 24071849 PMC3919969 NIHMS549280
433: Michels KB, Binder AM, Dedeurwaerder S, Epstein CB, Greally JM, Gut I, Houseman EA, Izzi B, Kelsey KT, Meissner A, Milosavljevic A, Siegmund KD, Bock C, Irizarry RA
Recommendations for the design and analysis of epigenome-wide association studies.
Nat Methods 10: 949-55 (2013)
PM ID: 24076989
434: Schjerven H, McLaughlin J, Arenzana TL, Frietze S, Cheng D, Wadsworth SE, Lawson GW, Bensinger SJ, Farnham PJ, Witte ON, Smale ST
Selective regulation of lymphopoiesis and leukemogenesis by individual zinc fingers of Ikaros.
Nat Immunol 14: 1073-83 (2013)
PM ID: 24013668 PMC3800053 NIHMS516116
435: Wilson IM, Vucic EA, Enfield KS, Thu KL, Zhang YA, Chari R, Lockwood WW, Radulovich N, Starczynowski DT, Banáth JP, Zhang M, Pusic A, Fuller M, Lonergan KM, Rowbotham D, Yee J, English JC, Buys TP, Selamat SA, Laird-Offringa IA, Liu P, Anderson M, You M, Tsao MS, Brown CJ, Bennewith KL, Macaulay CE, Karsan A, Gazdar AF, Lam S, Lam WL
EYA4 is inactivated biallelically at a high frequency in sporadic lung cancer and is associated with familial lung cancer risk.
Oncogene : (2013)
PM ID: 24096489
436: Morgan-Bathke M, Lin HH, Chibly AM, Zhang W, Sun X, Chen CH, Flodby P, Borok Z, Wu R, Arnett D, Klein RR, Ann DK, Limesand KH
Deletion of ATG5 shows a role of autophagy in salivary homeostatic control.
J Dent Res 92: 911-7 (2013)
PM ID: 23884556 PMC3775371
437: Abeywardana T, Lin YH, Rott R, Engelender S, Pratt MR
Site-specific differences in proteasome-dependent degradation of monoubiquitinated α-synuclein.
Chem Biol 20: 1207-13 (2013)
PM ID: 24210006 PMC3855323 NIHMS530153
438: Xi G, Hu P, Qu C, Qiu S, Tong C, Ying QL
Induced neural stem cells generated from rat fibroblasts.
Genomics Proteomics Bioinformatics 11: 312-9 (2013)
PM ID: 24076032 PMC3908478 NIHMS550114
439: Chen WT, Zhu G, Pfaffenbach K, Kanel G, Stiles B, Lee AS
GRP78 as a regulator of liver steatosis and cancer progression mediated by loss of the tumor suppressor PTEN.
Oncogene : (2013)
PM ID: 24141775 PMC3994182 NIHMS550258
440: Wrangle J, Wang W, Koch A, Easwaran H, Mohammad HP, Vendetti F, Vancriekinge W, Demeyer T, Du Z, Parsana P, Rodgers K, Yen RW, Zahnow CA, Taube JM, Brahmer JR, Tykodi SS, Easton K, Carvajal RD, Jones PA, Laird PW, Weisenberger DJ, Tsai S, Juergens RA, Topalian SL, Rudin CM, Brock MV, Pardoll D, Baylin SB
Alterations of immune response of Non-Small Cell Lung Cancer with Azacytidine.
Oncotarget 4: 2067-79 (2013)
PM ID: 24162015 PMC3875770
441: Tam KW, Zhang W, Soh J, Stastny V, Chen M, Sun H, Thu K, Rios JJ, Yang C, Marconett CN, Selamat SA, Laird-Offringa IA, Taguchi A, Hanash S, Shames D, Ma X, Zhang MQ, Lam WL, Gazdar A
CDKN2A/p16 inactivation mechanisms and their relationship to smoke exposure and molecular features in non-small-cell lung cancer.
J Thorac Oncol 8: 1378-88 (2013)
PM ID: 24077454 PMC3951422 NIHMS514699
442: Kim K, Kim JM, Kim JS, Choi J, Lee YS, Neamati N, Song JS, Heo K, An W
VprBP has intrinsic kinase activity targeting histone H2A and represses gene transcription.
Mol Cell 52: 459-67 (2013)
PM ID: 24140421 PMC3851289 NIHMS531474
443: Blattler A, Farnham PJ
Cross-talk between site-specific transcription factors and DNA methylation states.
J Biol Chem 288: 34287-94 (2013)
PM ID: 24151070 PMC3843044
444: Kida A, Kahn M
Hypoxia selects for a quiescent, CML stem/leukemia initiating-like population dependent on CBP/catenin transcription.
Curr Mol Pharmacol 6: 204-10 (2013)
PM ID: 24720539
445: Trotta AP, Need EF, Selth LA, Chopra S, Pinnock CB, Leach DA, Coetzee GA, Butler LM, Tilley WD, Buchanan G
Knockdown of the cochaperone SGTA results in the suppression of androgen and PI3K/Akt signaling and inhibition of prostate cancer cell proliferation.
Int J Cancer 133: 2812-23 (2013)
PM ID: 23740762
446: Zeng N, Yang KT, Bayan JA, He L, Aggarwal R, Stiles JW, Hou X, Medina V, Abad D, Palian BM, Al-Abdullah I, Kandeel F, Johnson DL, Stiles BL
PTEN controls β-cell regeneration in aged mice by regulating cell cycle inhibitor p16ink4a.
Aging Cell 12: 1000-11 (2013)
PM ID: 23826727 PMC3838454 NIHMS504197
447: Luo B, Tseng CC, Adams GB, Lee AS
Deficiency of GRP94 in the hematopoietic system alters proliferation regulators in hematopoietic stem cells.
Stem Cells Dev 22: 3062-73 (2013)
PM ID: 23859598 PMC3856911
448: Liu R, Li X, Gao W, Zhou Y, Wey S, Mitra SK, Krasnoperov V, Dong D, Liu S, Li D, Zhu G, Louie S, Conti PS, Li Z, Lee AS, Gill PS
Monoclonal antibody against cell surface GRP78 as a novel agent in suppressing PI3K/AKT signaling, tumor growth, and metastasis.
Clin Cancer Res 19: 6802-11 (2013)
PM ID: 24048331
449: Chen GK, Chang X, Curtis C, Wang K
Precise inference of copy number alterations in tumor samples from SNP arrays.
Bioinformatics 29: 2964-70 (2013)
PM ID: 24021380 PMC3834792
450: Kim K, Lee B, Kim J, Choi J, Kim JM, Xiong Y, Roeder RG, An W
Linker Histone H1.2 cooperates with Cul4A and PAF1 to drive H4K31 ubiquitylation-mediated transactivation.
Cell Rep 5: 1690-703 (2013)
PM ID: 24360965 PMC3901356 NIHMS545033
451: Saito Y, Saito H, Liang G, Friedman JM
Epigenetic Alterations and MicroRNA Misexpression in Cancer and Autoimmune Diseases: a Critical Review.
Clin Rev Allergy Immunol : (2013)
PM ID: 24362548
452: Tsen F, Bhatia A, O'Brien K, Cheng CF, Chen M, Hay N, Stiles B, Woodley DT, Li W
Extracellular heat shock protein 90 signals through subdomain II and the NPVY motif of LRP-1 receptor to Akt1 and Akt2: a circuit essential for promoting skin cell migration in vitro and wound healing in vivo.
Mol Cell Biol 33: 4947-59 (2013)
PM ID: 24126057 PMC3889557
453: Shi J, Marconett CN, Duan J, Hyland PL, Li P, Wang Z, Wheeler W, Zhou B, Campan M, Lee DS, Huang J, Zhou W, Triche T, Amundadottir L, Warner A, Hutchinson A, Chen PH, Chung BS, Pesatori AC, Consonni D, Bertazzi PA, Bergen AW, Freedman M, Siegmund KD, Berman BP, Borok Z, Chatterjee N, Tucker MA, Caporaso NE, Chanock SJ, Laird-Offringa IA, Landi MT
Characterizing the genetic basis of methylome diversity in histologically normal human lung tissue.
Nat Commun 5: 3365 (2014)
PM ID: 24572595 PMC3982882 NIHMS562641
454: Shearn CT, Mercer KE, Orlicky DJ, Hennings L, Smathers-McCullough RL, Stiles BL, Ronis MJ, Petersen DR
Short term feeding of a high fat diet exerts an additive effect on hepatocellular damage and steatosis in liver-specific PTEN knockout mice.
PLoS One 9: e96553 (2014)
PM ID: 24818992 PMC4018288
455: Frietze S, O'Geen H, Littlepage LE, Simion C, Sweeney CA, Farnham PJ, Krig SR
Global analysis of ZNF217 chromatin occupancy in the breast cancer cell genome reveals an association with ERalpha.
BMC Genomics 15: 520 (2014)
PM ID: 24962896 PMC4082627
456: Zhu G, Wang M, Spike B, Gray PC, Shen J, Lee SH, Chen SY, Lee AS
Differential requirement of GRP94 and GRP78 in mammary gland development.
Sci Rep 4: 5390 (2014)
PM ID: 24953136 PMC4066247
457: Cozen W, Timofeeva MN, Li D, Diepstra A, Hazelett D, Delahaye-Sourdeix M, Edlund CK, Franke L, Rostgaard K, Van Den Berg DJ, Cortessis VK, Smedby KE, Glaser SL, Westra HJ, Robison LL, Mack TM, Ghesquieres H, Hwang AE, Nieters A, de Sanjose S, Lightfoot T, Becker N, Maynadie M, Foretova L, Roman E, Benavente Y, Rand KA, Nathwani BN, Glimelius B, Staines A, Boffetta P, Link BK, Kiemeney L, Ansell SM, Bhatia S, Strong LC, Galan P, Vatten L, Habermann TM, Duell EJ, Lake A, Veenstra RN, Visser L, Liu Y, Urayama KY, Montgomery D, Gaborieau V, Weiss LM, Byrnes G, Lathrop M, Cocco P, Best T, Skol AD, Adami HO, Melbye M, Cerhan JR, Gallagher A, Taylor GM, Slager SL, Brennan P, Coetzee GA, Conti DV, Onel K, Jarrett RF, Hjalgrim H, van den Berg A, McKay JD
A meta-analysis of Hodgkin lymphoma reveals 19p13.3 TCF3 as a novel susceptibility locus.
Nat Commun 5: 3856 (2014)
PM ID: 24920014 PMC4055950 NIHMS585587
458: Gurel Z, Zaro BW, Pratt MR, Sheibani N
Identification of O-GlcNAc modification targets in mouse retinal pericytes: implication of p53 in pathogenesis of diabetic retinopathy.
PLoS One 9: e95561 (2014)
PM ID: 24788674 PMC4006792
459: St Pourcain B, Skuse DH, Mandy WP, Wang K, Hakonarson H, Timpson NJ, Evans DM, Kemp JP, Ring SM, McArdle WL, Golding J, Smith GD
Variability in the common genetic architecture of social-communication spectrum phenotypes during childhood and adolescence.
Mol Autism 5: 18 (2014)
PM ID: 24564958 PMC3940728
460: Ling C, Pease M, Shi L, Punj V, Shiroishi MS, Commins D, Weisenberger DJ, Wang K, Zada G
A pilot genome-scale profiling of DNA methylation in sporadic pituitary macroadenomas: association with tumor invasion and histopathological subtype.
PLoS One 9: e96178 (2014)
PM ID: 24781529 PMC4004564
461: He K, Xu T, Xu Y, Ring A, Kahn M, Goldkorn A
Cancer cells acquire a drug resistant, highly tumorigenic, cancer stem-like phenotype through modulation of the PI3K/Akt/β-catenin/CBP pathway.
Int J Cancer 134: 43-54 (2014)
PM ID: 23784558
462: Lee JS, Xiao J, Patel P, Schade J, Wang J, Deneen B, Erdreich-Epstein A, Song HR
A novel tumor-promoting role for nuclear factor IA in glioblastomas is mediated through negative regulation of p53, p21, and PAI1.
Neuro Oncol 16: 191-203 (2014)
PM ID: 24305710 PMC3895381
463: Blackwell TS, Tager AM, Borok Z, Moore BB, Schwartz DA, Anstrom KJ, Bar-Joseph Z, Bitterman P, Blackburn MR, Bradford W, Brown KK, Chapman HA, Collard HR, Cosgrove GP, Deterding R, Doyle R, Flaherty KR, Garcia CK, Hagood JS, Henke CA, Herzog E, Hogaboam CM, Horowitz JC, King TE, Loyd JE, Lawson WE, Marsh CB, Noble PW, Noth I, Sheppard D, Olsson J, Ortiz LA, O'Riordan TG, Oury TD, Raghu G, Roman J, Sime PJ, Sisson TH, Tschumperlin D, Violette SM, Weaver TE, Wells RG, White ES, Kaminski N, Martinez FJ, Wynn TA, Thannickal VJ, Eu JP
Future directions in idiopathic pulmonary fibrosis research. An NHLBI workshop report.
Am J Respir Crit Care Med 189: 214-22 (2014)
PM ID: 24160862 PMC3983890
464: Hughes MW, Jiang TX, Lin SJ, Leung Y, Kobielak K, Widelitz RB, Chuong CM
Disrupted ectodermal organ morphogenesis in mice with a conditional histone deacetylase 1, 2 deletion in the epidermis.
J Invest Dermatol 134: 24-32 (2014)
PM ID: 23792463 PMC3843967 NIHMS495764
465: Hazelett DJ, Rhie SK, Gaddis M, Yan C, Lakeland DL, Coetzee SG, Ellipse/GAME-ON consortium , PRACTICAL Consortium , Henderson BE, Noushmehr H, Cozen W, Kote-Jarai Z, Eeles RA, Easton DF, Haiman CA, Lu W, Farnham PJ, Coetzee GA
Comprehensive functional annotation of 77 prostate cancer risk loci.
PLoS Genet 10: e1004102 (2014)
PM ID: 24497837 PMC3907334
466: Bai Z, Huang Y, Li W, Zhu Y, Jung JU, Lu C, Gao SJ
Genomewide mapping and screening of Kaposi's sarcoma-associated herpesvirus (KSHV) 3' untranslated regions identify bicistronic and polycistronic viral transcripts as frequent targets of KSHV microRNAs.
J Virol 88: 377-92 (2014)
PM ID: 24155407 PMC3911756
467: Jones PA
At the tipping point for epigenetic therapies in cancer.
J Clin Invest 124: 14-6 (2014)
PM ID: 24382384 PMC3871262
468: Jeong KW, Andreu-Vieyra C, You JS, Jones PA, Stallcup MR
Establishment of active chromatin structure at enhancer elements by mixed-lineage leukemia 1 to initiate estrogen-dependent gene expression.
Nucleic Acids Res 42: 2245-56 (2014)
PM ID: 24288367 PMC3936730
469: Erdreich-Epstein A, Robison N, Ren X, Zhou H, Xu J, Davidson TB, Schur M, Gilles FH, Ji L, Malvar J, Shackleford GM, Margol AS, Krieger MD, Judkins AR, Jones DT, Pfister SM, Kool M, Sposto R, Asgharazadeh S
PID1 (NYGGF4), a new growth-inhibitory gene in embryonal brain tumors and gliomas.
Clin Cancer Res 20: 827-36 (2014)
PM ID: 24300787 PMC3962776 NIHMS545406
470: Berchuck A, Eeles RA, Amin Al Olama A, Kote-Jarai Z, Benlloch S, Antoniou A, McGuffog L, Offit K, Lee A, Dicks E, Luccarini C, Tessier DC, Bacot F, Vincent D, LaBoissière S, Robidoux F, Nielsen SF, Cunningham JM, Windebank SA, Hilker CA, Meyer J, Angelakos M, Maskiell J, Cornelissen S, van der Schoot E, Rutgers E, Verhoef S, Hogervorst F, Boonyawongviroj P, Siriwanarungsan P, Hein A, Schrauder M, Rübner M, Oeser S, Landrith S, Williams E, Ryder-Mills E, Sargus K, McInerney N, Colleran G, Rowan A, Jones A, of Sohn C, Schneeweiss A, Bugert P, Osorio A, Barroso A, Fernández V, González-Niera M, Malats N, Real F, Herráez B, Álvarez N, Díaz E, Miguel-Martin M, Bernstein L, Lacey J, Wang S, Ma H, Lu Y, Clague DeHart J, Deapen D, Pinder R, Lee E, Schumacher F, Horn-Ross P, Reynolds P, Nelson D, Park H, Ziegler H, Wolf S, Hermann V, Fischer-Bosch M, Lo WY, Justenhoven C, Yon-Dschun K, Baisch C, Fischer HP, Pesch B, Rabstein S, Lotz A, Harth V, Heikkinen T, Erkkilä I, Aaltonene K, von Smitten K, Antonenkova N, Hillemanns P, Christiansen H, Myöhänen E, Kemiläinen H, Thorne H, Niedermayr E, Botwell D, Chenevix-Trench G, Defazio A, Gertig D, Green A, Webb P, Parsons P, Hayward N, Webb P, Whiteman D, Fung A, Yashiki J, Peuteman G, Smeets D, Van Brussel T, Corthouts K, Obi N, Heinz J, Behrens S, Eilber U, Celik M, Olchers T, Peissel B, Scuvera G, Zaffaroni D, Bonanni B, Barile M, Feroce I, Tranchant M, Valois MF, Turgeon A, Heguy L, Yee PS, Kang P, Nee KI, Mariapun S, Sook-Ye Y, Lee D, Ching TY, Mohd Taib NA, Otsukka M, Mononen K, Selander T, Weerasooriya N, Krol-Warmerdam E, Molenaar J, Blom J, Brinton L, Szeszenia-Dabrowska N, Peplonska B, Zatonski W, Chao P, Stagner M, Bos P, Blom J, Crepin E, Nieuwlaat A, Heemskerk A, Higham S, Cross S, Cramp H, Conley D, Luccarini C, Conroy D, Baynes C, Chua K, Pilarski R, Agarwal D, Pineda S, Michailidou K, Herranz J, Pita G, Moreno LT, Alonso MR, Dennis J, Wang Q, Bolla MK, Meyer KB, Menéndez-Rodríguez P, Hardisson D, Mendiola M, González-Neira A, Lindblom A, Margolin S, Swerdlow A, Ashworth A, Orr N, Jones M, Matsuo K, Ito H, Iwata H, Kondo N, kConFab Investigators , Australian Ovarian Cancer Study Group , Hartman M, Hui M, Lim WY, Iau PT, Sawyer E, Tomlinson I, Kerin M, Miller N, Kang D, Choi J-, Park SK, Noh D-, Hopper JL, Schmidt DF, Makalic E, Southey MC, Teo SH, Yip CH, Sivanandan K, Tay W-, Brauch H, Brüning T, Hamann U, Genica Network , Dunning AM, Shah M, Andrulis IL, Knight JA, Glendon G, Tchatchou S, Schmidt MK, Broeks A, Rosenberg EH, van't Veer LJ, Fasching PA, Renner SP, Ekici AB, Beckmann MW, Shen C-, Hsiung C-, Yu J-, Hou M-, Blot W, Cai Q, Wu AH, Tseng C-, Van Den Berg D, Stram DO, Cox A, Brock IW, Reed MW, Muir K, Lophatananon A, Stewart-Brown S, Siriwanarangsan P, Zheng W, Deming-Halverson S, Shrubsole MJ, Long J, Shu X-, Lu W, Gao Y-, Zhang B, Radice P, Peterlongo P, Manoukian S, Mariette F, Sangrajrang S, McKay J, Couch FJ, Toland AE, TNBCC , Yannoukakos D, Fletcher O, Johnson N, dos Santos Silva I, Peto J, Marme F, Burwinkel B, Guénel P, Truong T, Sanchez M, Mulot C, Bojesen SE, Nordestgaard BG, Flyer H, Brenner H, Dieffenbach AK, Arndt V, Stegmaier C, Mannermaa A, Kataja V, Kosma V-, Hartikainen JM, Lambrechts D, Yesilyurt BT, Floris G, Leunen K, Chang-Claude J, Rudolph A, Seibold P, Flesch-Janys D, Wang X, Olson JE, Vachon C, Purrington K, Giles GG, Severi G, Baglietto L, Haiman CA, Henderson BE, Schumacher F, Marchand LL, Simard J, Dumont M, Goldberg MS, Labréche F, Winqvist R, Pylkäs K, Jukkola-Vuorinen A, Grip M, Devilee P, Tollenaar RA, Seynaeve C, García-Closas M, Chanock SJ, Lissowska J, Figueroa JD, Czene K, Eriksson M, Humphreys K, Darabi H, Hooning MJ, Kriege M, Collée JM, Tilanus-Linthorst M, Li J, Jakubowska A, Lubinski J, Jaworska-Bieniek K, Durda K, Nevanlinna H, Muranen TA, Aittomäki K, Blomqvist C, Bogdanova N, Dörk T, Hall P, Chenevix-Trench G, Easton DF, Pharroah PD, Arias-Perez JI, Zamora P, Benítez J, Milne RL
FGF receptor genes and breast cancer susceptibility: results from the Breast Cancer Association Consortium.
Br J Cancer 110: 1088-100 (2014)
PM ID: 24548884 PMC3929867
471: Li H, Chiappinelli KB, Guzzetta AA, Easwaran H, Yen RW, Vatapalli R, Topper MJ, Luo J, Connolly RM, Azad NS, Stearns V, Pardoll DM, Davidson N, Jones PA, Slamon DJ, Baylin SB, Zahnow CA, Ahuja N
Immune regulation by low doses of the DNA methyltransferase inhibitor 5-azacitidine in common human epithelial cancers.
Oncotarget 5: 587-98 (2014)
PM ID: 24583822 PMC3996658
472: Gundimeda U, McNeill TH, Fan TK, Deng R, Rayudu D, Chen Z, Cadenas E, Gopalakrishna R
Green tea catechins potentiate the neuritogenic action of brain-derived neurotrophic factor: role of 67-kDa laminin receptor and hydrogen peroxide.
Biochem Biophys Res Commun 445: 218-24 (2014)
PM ID: 24508265
473: Yang KT, Bayan JA, Zeng N, Aggarwal R, He L, Peng Z, Kassa A, Kim M, Luo Z, Shi Z, Medina V, Boddupally K, Stiles BL
Adult-onset deletion of Pten increases islet mass and beta cell proliferation in mice.
Diabetologia 57: 352-61 (2014)
PM ID: 24162585 PMC3918745 NIHMS535261
474: Pedersen JS, Valen E, Velazquez AM, Parker BJ, Rasmussen M, Lindgreen S, Lilje B, Tobin DJ, Kelly TK, Vang S, Andersson R, Jones PA, Hoover CA, Tikhonov A, Prokhortchouk E, Rubin EM, Sandelin A, Gilbert MT, Krogh A, Willerslev E, Orlando L
Genome-wide nucleosome map and cytosine methylation levels of an ancient human genome.
Genome Res 24: 454-66 (2014)
PM ID: 24299735 PMC3941110
475: Chen WT, Tseng CC, Pfaffenbach K, Kanel G, Luo B, Stiles BL, Lee AS
Liver-specific knockout of GRP94 in mice disrupts cell adhesion, activates liver progenitor cells, and accelerates liver tumorigenesis.
Hepatology 59: 947-57 (2014)
PM ID: 24027047
476: Chu Q, Cai L, Fu Y, Chen X, Yan Z, Lin X, Zhou G, Han H, Widelitz RB, Chuong CM, Wu W, Yue Z
Dkk2/Frzb in the dermal papillae regulates feather regeneration.
Dev Biol 387: 167-78 (2014)
PM ID: 24463139
477: Chodankar R, Wu DY, Schiller BJ, Yamamoto KR, Stallcup MR
Hic-5 is a transcription coregulator that acts before and/or after glucocorticoid receptor genome occupancy in a gene-selective manner.
Proc Natl Acad Sci U S A 111: 4007-12 (2014)
PM ID: 24591583 PMC3964041
478: Weinstein JN, Akbani R, Broom BM, Wang W, Verhaak RG, McConkey D, Lerner S, Morgan M, Creighton CJ, Smith C, Kwiatkowski DJ, Cherniack AD, Kim J, Sekhar Pedamallu C, Noble MS, Al-Ahmadie HA, Reuter VE, Rosenberg JE, Bajorin DF, Bochner BH, Solit DB, Koppie T, Robinson B, Gordenin DA, Fargo D, Klimczak LJ, Roberts SA, Au J, Laird PW, Hinoue T, Schultz N, Ramirez R, Hansel D, Hoadley KA, Kim WY, Damrauer JS, Baylin SB, Mungall AJ, Robertson AG, Chu A, Kwiatkowski DJ, Sougnez C, Cibulskis K, Lichtenstein L, Sivachenko A, Stewart C, Lawrence MS, Getz G, Lander E, Gabriel SB, Creighton CJ, Donehower L, Cherniack AD, Kim J, Carter SL, Saksena G, Schumacher SE, Sougnez C, Freeman SS, Jung J, Sekhar Pedamallu C, Bhatt AS, Pugh T, Getz G, Beroukhim R, Gabriel SB, Meyerson M, Mungall AJ, Robertson AG, Chu A, Ally A, Balasundaram M, Butterfield YS, Dhalla N, Hirst C, Holt RA, Jones SJ, Lee D, Li HI, Marra MA, Mayo M, Moore RA, Schein JE, Sipahimalani P, Tam A, Thiessen N, Wong T, Wye N, Bowlby R, Chuah E, Guin R, Jones SJ, Marra MA, Hinoue T, Shen H, Bootwalla MS, Triche T, Lai PH, Van Den Berg DJ, Weisenberger DJ, Laird PW, Hansel D, Hoadley KA, Balu S, Bodenheimer T, Damrauer JS, Hoyle AP, Jefferys SR, Meng S, Mose LE, Simons JV, Soloway MG, Wu J, Kim WY, Parker JS, Hayes DN, Roach J, Buda E, Jones CD, Mieczkowski PA, Tan D, Veluvolu U, Waring S, Auman JT, Perou CM, Wilkerson MD, Santoso N, Parfenov M, Ren X, Pantazi A, Hadjipanayis A, Seidman J, Kucherlapati R, Lee S, Yang L, Park PJ, Baylin SB, Wei Xu A, Protopopov A, Zhang J, Bristow C, Mahadeshwar HS, Seth S, Song X, Tang J, Zeng D, Chin L, Guo C, Weinstein JN, Akbani R, Broom BM, McConkey D, Casasent TD, Liu W, Ju Z, Motter T, Peng B, Ryan M, Wang W, Verhaak RG, Su X, Yang JY, Lorenzi PL, Yao H, Zhang N, Zhang J, Mills GB, Kim J, Noble MS, Cho J, DiCara D, Frazer S, Gehlenborg N, Heiman DI, Lin P, Liu Y, Stojanov P, Voet D, Zhang H, Zou L, Chin L, Getz G, Bernard B, Kreisberg D, Reynolds S, Rovira H, Shmulevich I, Ramirez R, Schultz N, Gao J, Jacobsen A, Aksoy BA, Antipin Y, Ciriello G, Dresdner G, Gross B, Lee W, Reva B, Shen R, Sinha R, Sumer SO, Weinhold N, Ladanyi M, Sander C, Benz C, Carlin D, Haussler D, Ng S, Paull EO, Stuart J, Zhu J, Liu Y, Zhang W, Taylor BS, Lichtenberg TM, Zmuda E, Barr T, Black AD, George M, Hanf B, Helsel C, McAllister C, Ramirez NC, Tabler TR, Weaver S, Wise L, Bowen J, Gastier-Foster JM, Weinstein JN, Lerner S, Jian W, Tello S, Ittman M, Castro P, McClenden WD, Morgan M, Gibbs R, Liu Y, Saller C, Tarvin K, DiPiero JM, Owens J, Bollag R, Li Q, Weinberger P, Czerwinski C, Huelsenbeck-Dill L, Iacocca M, Petrelli N, Rabeno B, Swanson P, Shelton T, Curley E, Gardner J, Mallery D, Penny R, Van Bang N, Thi Hanh P, Kohl B, Van Le X, Duc Phu B, Thorp R, Viet Tien N, Quang Vinh L, Sandusky G, Burks E, Christ K, Gee J, Holway A, Moinzadeh A, Sorcini A, Sullivan T, Al-Ahmadie HA, Bajorin DF, Bochner BH, Garcia-Grossman IR, Regazzi AM, Solit DB, Rosenberg JE, Reuter VE, Koppie T, Boice L, Kimryn Rathmell W, Thorne L, Bastacky S, Davies B, Dhir R, Gingrich J, Hrebinko R, Maranchie J, Nelson J, Parwani A, Bshara W, Gaudioso C, Morrison C, Alexopoulou V, Bartlett J, Engel J, Kodeeswaran S, Antic T, O'Donnell PH, Smith ND, Steinberg GD, Egea S, Gomez-Fernandez C, Herbert L, Jorda M, Soloway M, Beaver A, Carter S, Kapur P, Lewis C, Lotan Y, Robinson B, Hansel D, Guo C, Bondaruk J, Czerniak B, Akbani R, Broom BM, Liu Y, Zhang W, Weinstein JN, Lerner S, Morgan M, Kim J, Cherniack AD, Freeman SS, Sekhar Pedamallu C, Noble MS, Kwiatkowski DJ, Al-Ahmadie HA, Bajorin DF, Bochner BH, Solit DB, Rosenberg JE, Reuter VE, Koppie T, Robinson B, Skinner E, Ramirez R, Schultz N, Hansel D, Kim WY, Guo C, Bondaruk J, Aldape K, Czerniak B, Jensen MA, Kahn AB, Pihl TD, Pot DA, Srinivasan D, Wan Y, Ferguson ML, Zenklusen JC, Davidsen T, Demchok JA, Mills Shaw KR, Sheth M, Tarnuzzer R, Wang Z, Yang L, Hutter C, Ozenberger BA, Sofia HJ, Eley G, Cancer Genome Atlas Research Network
Comprehensive molecular characterization of urothelial bladder carcinoma.
Nature 507: 315-22 (2014)
PM ID: 24476821 PMC3962515 NIHMS551110
479: Gang EJ, Hsieh YT, Pham J, Zhao Y, Nguyen C, Huantes S, Park E, Naing K, Klemm L, Swaminathan S, Conway EM, Pelus LM, Crispino J, Mullighan CG, McMillan M, Müschen M, Kahn M, Kim YM
Small-molecule inhibition of CBP/catenin interactions eliminates drug-resistant clones in acute lymphoblastic leukemia.
Oncogene 33: 2169-78 (2014)
PM ID: 23728349 PMC3994178 NIHMS560207
480: Páez D, Gerger A, Zhang W, Yang D, Labonte MJ, Benhanim L, Kahn M, Lenz F, Lenz C, Ning Y, Wakatsuki T, Loupakis F, Lenz HJ
Association of common gene variants in the WNT/β-catenin pathway with colon cancer recurrence.
Pharmacogenomics J 14: 142-50 (2014)
PM ID: 23817222
481: Biancolella M, Fortini BK, Tring S, Plummer SJ, Mendoza-Fandino GA, Hartiala J, Hitchler MJ, Yan C, Schumacher FR, Conti DV, Edlund CK, Noushmehr H, Coetzee SG, Bresalier RS, Ahnen DJ, Barry EL, Berman BP, Rice JC, Coetzee GA, Casey G
Identification and characterization of functional risk variants for colorectal cancer mapping to chromosome 11q23.1.
Hum Mol Genet 23: 2198-209 (2014)
PM ID: 24256810 PMC3959808
482: Lay FD, Triche TJ, Tsai YC, Su SF, Martin SE, Daneshmand S, Skinner EC, Liang G, Chihara Y, Jones PA
Reprogramming of the human intestinal epigenome by surgical tissue transposition.
Genome Res 24: 545-53 (2014)
PM ID: 24515120 PMC3975055
483: Lin YH, Pratt MR
A dual small-molecule rheostat for precise control of protein concentration in Mammalian cells.
Chembiochem 15: 805-9 (2014)
PM ID: 24615791 PMC4038124 NIHMS584875
484: Breton CV, Park C, Siegmund K, Gauderman WJ, Whitfield-Maxwell L, Hodis HN, Avol E, Gilliland FD
NOS1 methylation and carotid artery intima-media thickness in children.
Circ Cardiovasc Genet 7: 116-22 (2014)
PM ID: 24622112 PMC4008829 NIHMS575192
485: Geary LA, Nash KA, Adisetiyo H, Liang M, Liao CP, Jeong JH, Zandi E, Roy-Burman P
CAF-secreted annexin A1 induces prostate cancer cells to gain stem cell-like features.
Mol Cancer Res 12: 607-21 (2014)
PM ID: 24464914 PMC3989391 NIHMS559276
486: Lee AS
Glucose-regulated proteins in cancer: molecular mechanisms and therapeutic potential.
Nat Rev Cancer 14: 263-76 (2014)
PM ID: 24658275
487: Su SF, de Castro Abreu AL, Chihara Y, Tsai Y, Andreu-Vieyra C, Daneshmand S, Skinner EC, Jones PA, Siegmund KD, Liang G
A panel of three markers hyper- and hypomethylated in urine sediments accurately predicts bladder cancer recurrence.
Clin Cancer Res 20: 1978-89 (2014)
PM ID: 24691641
488: Kellis M, Wold B, Snyder MP, Bernstein BE, Kundaje A, Marinov GK, Ward LD, Birney E, Crawford GE, Dekker J, Dunham I, Elnitski LL, Farnham PJ, Feingold EA, Gerstein M, Giddings MC, Gilbert DM, Gingeras TR, Green ED, Guigo R, Hubbard T, Kent J, Lieb JD, Myers RM, Pazin MJ, Ren B, Stamatoyannopoulos JA, Weng Z, White KP, Hardison RC
Defining functional DNA elements in the human genome.
Proc Natl Acad Sci U S A 111: 6131-8 (2014)
PM ID: 24753594 PMC4035993
489: Rosekrans SL, Heijmans J, Büller NV, Westerlund J, Lee AS, Muncan V, van den Brink GR
ER stress induces epithelial differentiation in the mouse oesophagus.
Gut : (2014)
PM ID: 24789843
490: Huang G, Yan H, Ye S, Tong C, Ying QL
STAT3 phosphorylation at tyrosine 705 and serine 727 differentially regulates mouse ESC fates.
Stem Cells 32: 1149-60 (2014)
PM ID: 24302476
491: Borok Z
Alveolar epithelium: beyond the barrier.
Am J Respir Cell Mol Biol 50: 853-6 (2014)
PM ID: 24783957 PMC4068954
492: Li W, Dai C, Kang S, Zhou XJ
Integrative analysis of many RNA-seq datasets to study alternative splicing.
Methods 67: 313-24 (2014)
PM ID: 24583115 PMC4120771 NIHMS580551
493: Lenz HJ, Kahn M
Safely targeting cancer stem cells via selective catenin coactivator antagonism.
Cancer Sci : (2014)
PM ID: 24975284
494: Sebio A, Kahn M, Lenz HJ
The potential of targeting Wnt/β-catenin in colon cancer.
Expert Opin Ther Targets 18: 611-5 (2014)
PM ID: 24702624
495: Antony R, Wong KE, Patel M, Olch AJ, McComb G, Krieger M, Gilles F, Sposto R, Erdreich-Epstein A, Dhall G, Gardner S, Finlay JL
A retrospective analysis of recurrent intracranial ependymoma.
Pediatr Blood Cancer 61: 1195-201 (2014)
PM ID: 24615997
496: Wu JB, Shao C, Li X, Li Q, Hu P, Shi C, Li Y, Chen YT, Yin F, Liao CP, Stiles BL, Zhau HE, Shih JC, Chung LW
Monoamine oxidase A mediates prostate tumorigenesis and cancer metastasis.
J Clin Invest 124: 2891-908 (2014)
PM ID: 24865426 PMC4071401
497: Wang Z, Zhu B, Zhang M, Parikh H, Jia J, Chung CC, Sampson JN, Hoskins JW, Hutchinson A, Burdette L, Ibrahim A, Hautman C, Raj PS, Abnet CC, Adjei AA, Ahlbom A, Albanes D, Allen NE, Ambrosone CB, Aldrich M, Amiano P, Amos C, Andersson U, Andriole G, Andrulis IL, Arici C, Arslan AA, Austin MA, Baris D, Barkauskas DA, Bassig BA, Beane Freeman LE, Berg CD, Berndt SI, Bertazzi PA, Biritwum RB, Black A, Blot W, Boeing H, Boffetta P, Bolton K, Boutron-Ruault MC, Bracci PM, Brennan P, Brinton LA, Brotzman M, Bueno-de-Mesquita HB, Buring JE, Butler MA, Cai Q, Cancel-Tassin G, Canzian F, Cao G, Caporaso NE, Carrato A, Carreon T, Carta A, Chang GC, Chang IS, Chang-Claude J, Che X, Chen CJ, Chen CY, Chen CH, Chen C, Chen KY, Chen YM, Chokkalingam AP, Chu LW, Clavel-Chapelon F, Colditz GA, Colt JS, Conti D, Cook MB, Cortessis VK, Crawford ED, Cussenot O, Davis FG, De Vivo I, Deng X, Ding T, Dinney CP, Di Stefano AL, Diver WR, Duell EJ, Elena JW, Fan JH, Feigelson HS, Feychting M, Figueroa JD, Flanagan AM, Fraumeni JF, Freedman ND, Fridley BL, Fuchs CS, Gago-Dominguez M, Gallinger S, Gao YT, Gapstur SM, Garcia-Closas M, Garcia-Closas R, Gastier-Foster JM, Gaziano JM, Gerhard DS, Giffen CA, Giles GG, Gillanders EM, Giovannucci EL, Goggins M, Gokgoz N, Goldstein AM, Gonzalez C, Gorlick R, Greene MH, Gross M, Grossman HB, Grubb R, Gu J, Guan P, Haiman CA, Hallmans G, Hankinson SE, Harris CC, Hartge P, Hattinger C, Hayes RB, He Q, Helman L, Henderson BE, Henriksson R, Hoffman-Bolton J, Hohensee C, Holly EA, Hong YC, Hoover RN, Hosgood HD, Hsiao CF, Hsing AW, Hsiung CA, Hu N, Hu W, Hu Z, Huang MS, Hunter DJ, Inskip PD, Ito H, Jacobs EJ, Jacobs KB, Jenab M, Ji BT, Johansen C, Johansson M, Johnson A, Kaaks R, Kamat AM, Kamineni A, Karagas M, Khanna C, Khaw KT, Kim C, Kim IS, Kim YH, Kim YC, Kim YT, Kang CH, Jung YJ, Kitahara CM, Klein AP, Klein R, Kogevinas M, Koh WP, Kohno T, Kolonel LN, Kooperberg C, Kratz CP, Krogh V, Kunitoh H, Kurtz RC, Kurucu N, Lan Q, Lathrop M, Lau CC, Lecanda F, Lee KM, Lee MP, Le Marchand L, Lerner SP, Li D, Liao LM, Lim WY, Lin D, Lin J, Lindstrom S, Linet MS, Lissowska J, Liu J, Ljungberg B, Lloreta J, Lu D, Ma J, Malats N, Mannisto S, Marina N, Mastrangelo G, Matsuo K, McGlynn KA, McKean-Cowdin R, McNeill LH, McWilliams RR, Melin BS, Meltzer PS, Mensah JE, Miao X, Michaud DS, Mondul AM, Moore LE, Muir K, Niwa S, Olson SH, Orr N, Panico S, Park JY, Patel AV, Patino-Garcia A, Pavanello S, Peeters PH, Peplonska B, Peters U, Petersen GM, Picci P, Pike MC, Porru S, Prescott J, Pu X, Purdue MP, Qiao YL, Rajaraman P, Riboli E, Risch HA, Rodabough RJ, Rothman N, Ruder AM, Ryu JS, Sanson M, Schned A, Schumacher FR, Schwartz AG, Schwartz KL, Schwenn M, Scotlandi K, Seow A, Serra C, Serra M, Sesso HD, Severi G, Shen H, Shen M, Shete S, Shiraishi K, Shu XO, Siddiq A, Sierrasesumaga L, Sierri S, Loon Sihoe AD, Silverman DT, Simon M, Southey MC, Spector L, Spitz M, Stampfer M, Stattin P, Stern MC, Stevens VL, Stolzenberg-Solomon RZ, Stram DO, Strom SS, Su WC, Sund M, Sung SW, Swerdlow A, Tan W, Tanaka H, Tang W, Tang ZZ, Tardon A, Tay E, Taylor PR, Tettey Y, Thomas DM, Tirabosco R, Tjonneland A, Tobias GS, Toro JR, Travis RC, Trichopoulos D, Troisi R, Truelove A, Tsai YH, Tucker MA, Tumino R, Van Den Berg D, Van Den Eeden SK, Vermeulen R, Vineis P, Visvanathan K, Vogel U, Wang C, Wang C, Wang J, Wang SS, Weiderpass E, Weinstein SJ, Wentzensen N, Wheeler W, White E, Wiencke JK, Wolk A, Wolpin BM, Wong MP, Wrensch M, Wu C, Wu T, Wu X, Wu YL, Wunder JS, Xiang YB, Xu J, Yang HP, Yang PC, Yatabe Y, Ye Y, Yeboah ED, Yin Z, Ying C, Yu CJ, Yu K, Yuan JM, Zanetti KA, Zeleniuch-Jacquotte A, Zheng W, Zhou B, Mirabello L, Savage SA, Kraft P, Chanock SJ, Yeager M, Landi MT, Shi J, Chatterjee N, Amundadottir LT
Imputation and subset-based association analysis across different cancer types identifies multiple independent risk loci in the TERT-CLPTM1L region on chromosome 5p15.33.
Hum Mol Genet : (2014)
PM ID: 25027329
498: Liu Y, Yang R, Liu X, Zhou Y, Qu C, Kikuiri T, Wang S, Zandi E, Du J, Ambudkar IS, Shi S
Hydrogen sulfide maintains mesenchymal stem cell function and bone homeostasis via regulation of Ca(2+) channel sulfhydration.
Cell Stem Cell 15: 66-78 (2014)
PM ID: 24726192 PMC4082757 NIHMS578815
499: Tuzon CT, Spektor T, Kong X, Congdon LM, Wu S, Schotta G, Yokomori K, Rice JC
Concerted activities of distinct H4K20 methyltransferases at DNA double-strand breaks regulate 53BP1 nucleation and NHEJ-directed repair.
Cell Rep 8: 430-8 (2014)
PM ID: 25001286 PMC4134327 NIHMS606743
500: Collisson EA, Campbell JD, Brooks AN, Berger AH, Lee W, Chmielecki J, Beer DG, Cope L, Creighton CJ, Danilova L, Ding L, Getz G, Hammerman PS, Hayes DN, Hernandez B, Herman JG, Heymach JV, Jurisica I, Kucherlapati R, Kwiatkowski D, Ladanyi M, Robertson G, Schultz N, Shen R, Sinha R, Sougnez C, Tsao MS, Travis WD, Weinstein JN, Wigle DA, Wilkerson MD, Chu A, Cherniack AD, Hadjipanayis A, Rosenberg M, Weisenberger DJ, Laird PW, Radenbaugh A, Ma S, Stuart JM, Averett Byers L, Baylin SB, Govindan R, Meyerson M, Rosenberg M, Gabriel SB, Cibulskis K, Sougnez C, Kim J, Stewart C, Lichtenstein L, Lander ES, Lawrence MS, Getz G, Kandoth C, Fulton R, Fulton LL, McLellan MD, Wilson RK, Ye K, Fronick CC, Maher CA, Miller CA, Wendl MC, Cabanski C, Ding L, Mardis E, Govindan R, Creighton CJ, Wheeler D, Balasundaram M, Butterfield YS, Carlsen R, Chu A, Chuah E, Dhalla N, Guin R, Hirst C, Lee D, Li HI, Mayo M, Moore RA, Mungall AJ, Schein JE, Sipahimalani P, Tam A, Varhol R, Robertson A, Wye N, Thiessen N, Holt RA, Jones SJ, Marra MA, Campbell JD, Brooks AN, Chmielecki J, Imielinski M, Onofrio RC, Hodis E, Zack T, Sougnez C, Helman E, Sekhar Pedamallu C, Mesirov J, Cherniack AD, Saksena G, Schumacher SE, Carter SL, Hernandez B, Garraway L, Beroukhim R, Gabriel SB, Getz G, Meyerson M, Hadjipanayis A, Lee S, Mahadeshwar HS, Pantazi A, Protopopov A, Ren X, Seth S, Song X, Tang J, Yang L, Zhang J, Chen PC, Parfenov M, Wei Xu A, Santoso N, Chin L, Park PJ, Kucherlapati R, Hoadley KA, Auman JT, Meng S, Shi Y, Buda E, Waring S, Veluvolu U, Tan D, Mieczkowski PA, Jones CD, Simons JV, Soloway MG, Bodenheimer T, Jefferys SR, Roach J, Hoyle AP, Wu J, Balu S, Singh D, Prins JF, Marron JS, Parker JS, Hayes DN, Perou CM, Liu J, Cope L, Danilova L, Weisenberger DJ, Maglinte DT, Lai PH, Bootwalla MS, Van Den Berg DJ, Triche T, Baylin SB, Laird PW, Rosenberg M, Chin L, Zhang J, Cho J, DiCara D, Heiman D, Lin P, Mallard W, Voet D, Zhang H, Zou L, Noble MS, Lawrence MS, Saksena G, Gehlenborg N, Thorvaldsdottir H, Mesirov J, Nazaire MD, Robinson J, Getz G, Lee W, Aksoy BA, Ciriello G, Taylor BS, Dresdner G, Gao J, Gross B, Seshan VE, Ladanyi M, Reva B, Sinha R, Sumer SO, Weinhold N, Schultz N, Shen R, Sander C, Ng S, Ma S, Zhu J, Radenbaugh A, Stuart JM, Benz CC, Yau C, Haussler D, Spellman PT, Wilkerson MD, Parker JS, Hoadley KA, Kimes PK, Hayes DN, Perou CM, Broom BM, Wang J, Lu Y, Kwok Shing Ng P, Diao L, Averett Byers L, Liu W, Heymach JV, Amos CI, Weinstein JN, Akbani R, Mills GB, Curley E, Paulauskis J, Lau K, Morris S, Shelton T, Mallery D, Gardner J, Penny R, Saller C, Tarvin K, Richards WG, Cerfolio R, Bryant A, Raymond DP, Pennell NA, Farver C, Czerwinski C, Huelsenbeck-Dill L, Iacocca M, Petrelli N, Rabeno B, Brown J, Bauer T, Dolzhanskiy O, Potapova O, Rotin D, Voronina O, Nemirovich-Danchenko E, Fedosenko KV, Gal A, Behera M, Ramalingam SS, Sica G, Flieder D, Boyd J, Weaver J, Kohl B, Huy Quoc Thinh D, Sandusky G, Juhl H, Duhig E, Illei P, Gabrielson E, Shin J, Lee B, Rogers K, Trusty D, Brock MV, Williamson C, Burks E, Rieger-Christ K, Holway A, Sullivan T, Wigle DA, Asiedu MK, Kosari F, Travis WD, Rekhtman N, Zakowski M, Rusch VW, Zippile P, Suh J, Pass H, Goparaju C, Owusu-Sarpong Y, Bartlett JM, Kodeeswaran S, Parfitt J, Sekhon H, Albert M, Eckman J, Myers JB, Cheney R, Morrison C, Gaudioso C, Borgia JA, Bonomi P, Pool M, Liptay MJ, Moiseenko F, Zaytseva I, Dienemann H, Meister M, Schnabel PA, Muley TR, Peifer M, Gomez-Fernandez C, Herbert L, Egea S, Huang M, Thorne LB, Boice L, Hill Salazar A, Funkhouser WK, Rathmell WK, Dhir R, Yousem SA, Dacic S, Schneider F, Siegfried JM, Hajek R, Watson MA, McDonald S, Meyers B, Clarke B, Yang IA, Fong KM, Hunter L, Windsor M, Bowman RV, Peters S, Letovanec I, Khan KZ, Jensen MA, Snyder EE, Srinivasan D, Kahn AB, Baboud J, Pot DA, Mills Shaw KR, Sheth M, Davidsen T, Demchok JA, Yang L, Wang Z, Tarnuzzer R, Zenklusen JC, Ozenberger BA, Sofia HJ, Travis WD, Cheney R, Clarke B, Dacic S, Duhig E, Funkhouser WK, Illei P, Farver C, Rekhtman N, Sica G, Suh J, Tsao MS, Travis WD, Cheney R, Clarke B, Dacic S, Duhig E, Funkhouser WK, Illei P, Farver C, Rekhtman N, Sica G, Suh J, Tsao MS, Cancer Genome Atlas Research Network
Comprehensive molecular profiling of lung adenocarcinoma.
Nature 511: 543-50 (2014)
PM ID: 25079552
501: Bass AJ, Thorsson V, Shmulevich I, Reynolds SM, Miller M, Bernard B, Hinoue T, Laird PW, Curtis C, Shen H, Weisenberger DJ, Schultz N, Shen R, Weinhold N, Kelsen DP, Bowlby R, Chu A, Kasaian K, Mungall AJ, Gordon Robertson A, Sipahimalani P, Cherniack A, Getz G, Liu Y, Noble MS, Pedamallu C, Sougnez C, Taylor-Weiner A, Akbani R, Lee JS, Liu W, Mills GB, Yang D, Zhang W, Pantazi A, Parfenov M, Gulley M, Blanca Piazuelo M, Schneider BG, Kim J, Boussioutas A, Sheth M, Demchok JA, Rabkin CS, Willis JE, Ng S, Garman K, Beer DG, Pennathur A, Raphael BJ, Wu HT, Odze R, Kim HK, Bowen J, Leraas KM, Lichtenberg TM, Weaver S, McLellan M, Wiznerowicz M, Sakai R, Getz G, Sougnez C, Lawrence MS, Cibulskis K, Lichtenstein L, Fisher S, Gabriel SB, Lander ES, Ding L, Niu B, Ally A, Balasundaram M, Birol I, Bowlby R, Brooks D, Butterfield YS, Carlsen R, Chu A, Chu J, Chuah E, Chun HJ, Clarke A, Dhalla N, Guin R, Holt RA, Jones SJ, Kasaian K, Lee D, Li HA, Lim E, Ma Y, Marra MA, Mayo M, Moore RA, Mungall AJ, Mungall KL, Ming Nip K, Gordon Robertson A, Schein JE, Sipahimalani P, Tam A, Thiessen N, Beroukhim R, Carter SL, Cherniack AD, Cho J, Cibulskis K, DiCara D, Frazer S, Fisher S, Gabriel SB, Gehlenborg N, Heiman DI, Jung J, Kim J, Lander ES, Lawrence MS, Lichtenstein L, Lin P, Meyerson M, Ojesina AI, Sekhar Pedamallu C, Saksena G, Schumacher SE, Sougnez C, Stojanov P, Tabak B, Taylor-Weiner A, Voet D, Rosenberg M, Zack TI, Zhang H, Zou L, Protopopov A, Santoso N, Parfenov M, Lee S, Zhang J, Mahadeshwar HS, Tang J, Ren X, Seth S, Yang L, Xu AW, Song X, Pantazi A, Xi R, Bristow CA, Hadjipanayis A, Seidman J, Chin L, Park PJ, Kucherlapati R, Akbani R, Ling S, Liu W, Rao A, Weinstein JN, Kim SB, Lee JS, Lu Y, Mills G, Laird PW, Hinoue T, Weisenberger DJ, Bootwalla MS, Lai PH, Shen H, Triche Jr T, Van Den Berg DJ, Baylin SB, Herman JG, Getz G, Chin L, Liu Y, Murray BA, Noble MS, Arman Askoy RB, Ciriello G, Dresdner G, Gao J, Gross B, Jacobsen A, Lee W, Ramirez R, Sander C, Schultz N, Senbabaoglu Y, Sinha R, Onur Sumer S, Sun Y, Weinhold N, Thorsson V, Bernard B, Iype L, Kramer RW, Kreisberg R, Miller M, Reynolds SM, Rovira H, Tasman N, Shmulevich I, Ng S, Haussler D, Stuart JM, Akbani R, Ling S, Liu W, Rao A, Weinstein JN, Verhaak RG, Mills GB, Leiserson MD, Raphael BJ, Wu HT, Taylor BS, Black AD, Bowen J, Ann Carney J, Gastier-Foster JM, Helsel C, Leraas KM, Lichtenberg TM, McAllister C, Ramirez NC, Tabler TR, Wise L, Zmuda E, Penny R, Crain D, Gardner J, Lau K, Curely E, Mallery D, Morris S, Paulauskis J, Shelton T, Shelton C, Sherman M, Benz C, Lee JH, Fedosenko K, Manikhas G, Potapova O, Voronina O, Belyaev S, Dolzhansky O, Kimryn Rathmell W, Brzezinski J, Ibbs M, Korski K, Kycler W, Laźniak R, Leporowska E, Mackiewicz A, Murawa D, Murawa P, Spychała A, Suchorska WM, Tatka H, Teresiak M, Wiznerowicz M, Abdel-Misih R, Bennett J, Brown J, Iacocca M, Rabeno B, Kwon SY, Penny R, Gardner J, Kemkes A, Mallery D, Morris S, Shelton T, Shelton C, Curley E, Alexopoulou I, Engel J, Bartlett J, Albert M, Park DY, Dhir R, Luketich J, Landreneau R, Janjigian YY, Kelsen DP, Cho E, Ladanyi M, Tang L, McCall SJ, Park YS, Cheong JH, Ajani J, Constanza Camargo M, Alonso S, Ayala B, Jensen MA, Pihl T, Raman R, Walton J, Wan Y, Demchok JA, Eley G, Mills Shaw KR, Sheth M, Tarnuzzer R, Wang Z, Yang L, Claude Zenklusen J, Davidsen T, Hutter CM, Sofia HJ, Burton R, Chudamani S, Liu J, Burton R, Chudamani S, Liu J, The Cancer Genome Atlas Research Network , Analysis Working Group: Dana-Farber Cancer Institute , Institute for Systems Biology , University of Southern California , Memorial Sloan Kettering Cancer Center , BC Cancer Agency , The Eli &Edythe L. Broad Institute , MD Anderson Cancer Center , Harvard Medical School , University of North Carolina , Vanderbilt University , Asan Medical Center , University of Melbourne , National Cancer Institute , Case Western Reserve University , University of California at Santa Cruz , Duke University , University of Michigan , University of Pittsburgh , Brown University , Brigham and Women’s Hospital , National Cancer Center , Nationwide Children’s Hospital , Washington University , Greater Poland Cancer Centre , KU Leuven , Genome Sequencing Center: The Eli &Edythe L. Broad Institute , Washington University in St. Louis , Genome Characterization Centers: BC Cancer Agency , The Eli &Edythe L. Broad Institute , Harvard Medical School/Brigham &Women’s Hospital/MD Anderson Cancer Center , MD Anderson Cancer Center , University of Southern California Epigenome Center , The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University , Genome Data Analysis Centers: The Eli &Edythe L. Broad Institute , Memorial Sloan-Kettering Cancer Cente , Institute for Systems Biology , University of California, Santa Cruz , MD Anderson Cancer Center , Brown University , University of California San Francisco , Biospecimen Core Resource: The Research Institute at Nationwide Children’s Hospital , International Genomics Consortium , Tissue Source Sites: Buck Institute for Research on Aging , Chonnam National University Medical School , City Clinical Oncology Dispensary , Cureline , UNC Lineberger Comprehensive Cancer Center , Greater Poland Cancer Centre , Helen F. Graham Cancer Center &Research Institute , Keimyung University School of Medicine , International Genomics Consortium , Ontario Tumour Bank , Pusan National University Hospital , University of Pittsburgh School of Medicine , Disease Working Group: Memorial Sloan-Kettering Cancer Center , Duke University , Asan Medical Center , Yonsei University College of Medicine , MD Anderson Cancer Center , National Cancer Institute , Data Coordination Center: SRA International , Project Team: National Cancer Institute , SAIC-Frederick , Analysis Working Group Dana-Farber Cancer Institute , Institute for Systems Biology , University of Southern California , Memorial Sloan Kettering Cancer Center , BC Cancer Agency , The Eli Edythe L Broad Institute , MD Anderson Cancer Center , Harvard Medical School , University of North Carolina , Vanderbilt University , Asan Medical Center , University of Melbourne , National Cancer Institute , Case Western Reserve University , University of California at Santa Cruz , Duke University , University of Michigan , University of Pittsburgh , Brown University , Brigham and Women's Hospital , National Cancer Center , Nationwide Children's Hospital , Washington University , Greater Poland Cancer Centre , KU Leuven , Genome Sequencing Center The Eli Edythe L Broad Institute , Washington University in St Louis , Genome Characterization Centers BC Cancer Agency , The Eli Edythe L Broad Institute , Harvard Medical School/Brigham Women's Hospital/MD Anderson Cancer Center , MD Anderson Cancer Center , University of Southern California Epigenome Center , The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University , Genome Data Analysis Centers The Eli Edythe L Broad Institute , Memorial Sloan-Kettering Cancer Cente , Institute for Systems Biology , University of California Santa Cruz , MD Anderson Cancer Center , Brown University , University of California San Francisco , Biospecimen Core Resource The Research Institute at Nationwide Children's Hospital , International Genomics Consortium , Tissue Source Sites Buck Institute for Research on Aging , Chonnam National University Medical School , City Clinical Oncology Dispensary , Cureline , UNC Lineberger Comprehensive Cancer Center , Greater Poland Cancer Centre , Helen F Graham Cancer Center Research Institute , Keimyung University School of Medicine , International Genomics Consortium , Ontario Tumour Bank , Pusan National University Hospital , University of Pittsburgh School of Medicine , Disease Working Group Memorial Sloan-Kettering Cancer Center , Duke University , Asan Medical Center , Yonsei University College of Medicine , MD Anderson Cancer Center , National Cancer Institute , Data Coordination Center SRA International , Project Team National Cancer Institute , SAIC-Frederick , SAIC-Frederick
Comprehensive molecular characterization of gastric adenocarcinoma.
Nature : (2014)
PM ID: 25079317
502: Zaro BW, Chuh KN, Pratt MR
Chemical Reporter for Visualizing Metabolic Cross-Talk between Carbohydrate Metabolism and Protein Modification.
ACS Chem Biol : (2014)
PM ID: 25062036
503: Abeywardana T, Pratt MR
Using chemistry to investigate the molecular consequences of protein ubiquitylation.
Chembiochem 15: 1547-54 (2014)
PM ID: 24976261
504: Li G, Flodby P, Luo J, Kage H, Sipos A, Gao D, Ji Y, Beard LL, Marconett CN, Demaio L, Kim YH, Kim KJ, Laird-Offringa IA, Minoo P, Liebler JM, Zhou B, Crandall ED, Borok Z
Knockout mice reveal key roles for claudin 18 in alveolar barrier properties and fluid homeostasis.
Am J Respir Cell Mol Biol 51: 210-22 (2014)
PM ID: 24588076
505: Chen CC, Murray PJ, Jiang TX, Plikus MV, Chang YT, Lee OK, Widelitz RB, Chuong CM
Regenerative hair waves in aging mice and extra-follicular modulators follistatin, dkk1, and sfrp4.
J Invest Dermatol 134: 2086-96 (2014)
PM ID: 24618599 PMC4102635 NIHMS573140
506: Nandhu MS, Hu B, Cole SE, Erdreich-Epstein A, Rodriguez-Gil DJ, Viapiano MS
Novel paracrine modulation of Notch-DLL4 signaling by fibulin-3 promotes angiogenesis in high-grade gliomas.
Cancer Res : (2014)
PM ID: 25139440
507: Kage H, Flodby P, Gao D, Kim YH, Marconett CN, Demaio L, Kim KJ, Crandall ED, Borok Z
Claudin 4 knockout mice: normal physiologic phenotype with increased susceptibility to lung injury.
Am J Physiol Lung Cell Mol Physiol : (2014)
PM ID: 25106430
508: Creighton CJ, Davis CF, Morgan M, Gunaratne PH, Donehower LA, Kaipparettu BA, Wheeler DA, Gibbs RA, Signoretti S, Cherniack AD, Robertson AG, Chu A, Choueiri TK, Henske EP, Kwiatkowski DJ, Reuter V, Hsieh JJ, Hakimi AA, Tickoo SK, Ricketts C, Linehan WM, Schmidt LS, Gordenin DA, Bhanot G, Seiler M, Tamboli P, Rathmell WK, Fahey CC, Hacker KE, Smith AB, Wallen EM, Shen H, Laird PW, Shuch B, Muzny D, Buhay C, Wang M, Chao H, Dahdouli M, Xi L, Kakkar N, Reid JG, Downs B, Drummond J, Morton D, Doddapaneni H, Lewis L, English A, Meng Q, Kovar C, Wang Q, Hale W, Hawes A, Kalra D, Walker K, Murray BA, Sougnez C, Saksena G, Carter SL, Schumacher SE, Tabak B, Zack TI, Getz G, Beroukhim R, Gabriel SB, Meyerson M, Ally A, Balasundaram M, Birol I, Brooks D, Butterfield YS, Chuah E, Clarke A, Dhalla N, Guin R, Holt RA, Kasaian K, Lee D, Li HI, Lim E, Ma Y, Mayo M, Moore RA, Mungall AJ, Schein JE, Sipahimalani P, Tam A, Thiessen N, Wong T, Jones SJ, Marra MA, Auman JT, Tan D, Meng S, Jones CD, Hoadley KA, Mieczkowski PA, Mose LE, Jefferys SR, Roach J, Veluvolu U, Wilkerson MD, Waring S, Buda E, Wu J, Bodenheimer T, Hoyle AP, Simons JV, Soloway MG, Balu S, Parker JS, Hayes DN, Perou CM, Weisenberger DJ, Bootwalla MS, Triche T, Lai PH, Van Den Berg DJ, Baylin SB, Chen F, Coarfa C, Noble MS, DiCara D, Zhang H, Cho J, Heiman DI, Gehlenborg N, Voet D, Lin P, Frazer S, Stojanov P, Liu Y, Zou L, Kim J, Lawrence MS, Chin L, Yang L, Seth S, Bristow CA, Protopopov A, Song X, Zhang J, Pantazi A, Hadjipanayis A, Lee E, Luquette LJ, Lee S, Parfenov M, Santoso N, Seidman J, Xu AW, Kucherlapati R, Park PJ, Kang H, Lee J, Roberts SA, Klimczak LJ, Fargo D, Lang M, Choi YL, Kim SC, Lee JK, Park WY, Wang W, Fan Y, Ahn J, Akbani R, Weinstein JN, Haussler D, Ma S, Radenbaugh A, Zhul J, Biehl M, Lichtenberg TM, Zmuda E, Black AD, Hanf B, Ramirez NC, Wise L, Bowen J, Leraas KM, Hall TM, Gastier-Foster JM, Kaelin WG, Thorne L, Boice L, Huang M, Vocke C, Peterson J, Worrell R, Merino M, Czerniak BA, Aldape KD, Wood CG, Spellman PT, Atkins MB, Cheville J, Thompson RH, Jensen MA, Pihl T, Wan Y, Ayala B, Baboud J, Velaga S, Walton J, Liu J, Chudamani S, Wu Y, Sheth M, Mills Shaw KR, Demchok JA, Davidsen T, Yang L, Wang Z, Tarnuzzer RW, Zhang J, Eley G, Felau I, Zenklusen JC, Hutter CM, Guyer MS, Ozenberger BA, Sofia HJ, Davis CF, Ricketts CJ, Wang M, Yang L, Cherniack AD, Shen H, Buhay C, Kang H, Kim SC, Fahey CC, Hacker KE, Bhanot G, Gordenin DA, Chu A, Gunaratne PH, Biehl M, Seth S, Kaipparettu BA, Bristow CA, Donehower LA, Wallen EM, Smith AB, Tickoo SK, Tamboli P, Reuter V, Schmidt LS, Hsieh JJ, Choueiri TK, Hakimi AA, The Cancer Genome Atlas Research Network , Chin L, Meyerson M, Kucherlapati R, Park WY, Robertson AG, Laird PW, Henske EP, Kwiatkowski DJ, Park PJ, Morgan M, Shuch B, Muzny D, Wheeler DA, Linehan WM, Gibbs RA, Rathmell WK, Creighton CJ, The Cancer Genome Atlas Research Network
The Somatic Genomic Landscape of Chromophobe Renal Cell Carcinoma.
Cancer Cell : (2014)
PM ID: 25155756
509: Yilmaz Z, Kaplan AS, Tiwari AK, Levitan RD, Piran S, Bergen AW, Kaye WH, Hakonarson H, Wang K, Berrettini WH, Brandt HA, Bulik CM, Crawford S, Crow S, Fichter MM, Halmi KA, Johnson CL, Keel PK, Klump KL, Magistretti P, Mitchell JE, Strober M, Thornton LM, Treasure J, Woodside DB, Knight J, Kennedy JL
The role of leptin, melanocortin, and neurotrophin system genes on body weight in anorexia nervosa and bulimia nervosa.
J Psychiatr Res 55: 77-86 (2014)
PM ID: 24831852
510: Grimmer MR, Stolzenburg S, Ford E, Lister R, Blancafort P, Farnham PJ
Analysis of an artificial zinc finger epigenetic modulator: widespread binding but limited regulation.
Nucleic Acids Res : (2014)
PM ID: 25122745
511: Ye S, Liu D, Ying QL
Signaling pathways in induced naïve pluripotency.
Curr Opin Genet Dev 28C: 10-15 (2014)
PM ID: 25173148
512: Chuh KN, Zaro BW, Piller F, Piller V, Pratt MR
Changes in Metabolic Chemical Reporter Structure Yield a Selective Probe of O-GlcNAc Modification.
J Am Chem Soc 136: 12283-95 (2014)
PM ID: 25153642
513: Xue M, Yao S, Hu M, Li W, Hao T, Zhou F, Zhu X, Lu H, Qin D, Yan Q, Zhu J, Gao SJ, Lu C
HIV-1 Nef and KSHV oncogene K1 synergistically promote angiogenesis by inducing cellular miR-718 to regulate the PTEN/AKT/mTOR signaling pathway.
Nucleic Acids Res 42: 9862-79 (2014)
PM ID: 25104021