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USC Norris Comprehensive Cancer Center
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Publications for Norris Cancer Center Members in the Epigenetics and Regulation Program

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Total Number of Publications: 553
Inter Programmatic Publications: 214
Intra Programmatic Publications: 83

1: Gal-Yam EN, Saito Y, Egger G, Jones PA
Cancer epigenetics: modifications, screening, and therapy.
Annu Rev Med 59: 267-80 (2008)
PM ID: 17937590
2: Yang CK, Kim JH, Ann DK, Stallcup MR
Differential regulation of the two transcriptional activation domains of the coiled-coil coactivator CoCoA by sumoylation.
BMC Mol Biol 9: 12 (2008)
PM ID: 18218142 PMC2263068
3: Maxson R, Ishii M
The Bmp pathway in skull vault development.
Front Oral Biol 12: 197-208 (2008)
PM ID: 18391502
4: Chen YH, Ishii M, Sucov HM, Maxson RE
Msx1 and Msx2 are required for endothelial-mesenchymal transformation of the atrioventricular cushions and patterning of the atrioventricular myocardium.
BMC Dev Biol 8: 75 (2008)
PM ID: 18667074 PMC2518925
5: Siegmund KD, Marjoram P, Shibata D
Modeling DNA methylation in a population of cancer cells.
Stat Appl Genet Mol Biol 7: Article 18 (2008)
PM ID: 18597664
6: Anglim PP, Galler JS, Koss MN, Hagen JA, Turla S, Campan M, Weisenberger DJ, Laird PW, Siegmund KD, Laird-Offringa IA
Identification of a panel of sensitive and specific DNA methylation markers for squamous cell lung cancer.
Mol Cancer 7: 62 (2008)
PM ID: 18616821 PMC2483990
7: Jia L, Berman BP, Jariwala U, Yan X, Cogan JP, Walters A, Chen T, Buchanan G, Frenkel B, Coetzee GA
Genomic androgen receptor-occupied regions with different functions, defined by histone acetylation, coregulators and transcriptional capacity.
PLoS One 3: e3645 (2008)
PM ID: 18997859 PMC2577007
8: Anglim PP, Alonzo TA, Laird-Offringa IA
DNA methylation-based biomarkers for early detection of non-small cell lung cancer: an update.
Mol Cancer 7: 81 (2008)
PM ID: 18947422 PMC2585582
9: Magda D, Lecane PS, Prescott J, Thiemann P, Ma X, Dranchak PK, Toleno DM, Ramaswamy K, Siegmund KD, Hacia JG
mtDNA depletion confers specific gene expression profiles in human cells grown in culture and in xenograft.
BMC Genomics 9: 521 (2008)
PM ID: 18980691 PMC2612029
10: Minoo P, Hu L, Zhu NL, Borok Z, Bellusci S, Groffen J, Kardassis D, Li C
SMAD3 prevents binding of NKX2.1 and FOXA1 to the SpB promoter through its MH1 and MH2 domains.
Nucleic Acids Res 36: 179-88 (2008)
PM ID: 18003659 PMC2248754
11: Dong D, Ni M, Li J, Xiong S, Ye W, Virrey JJ, Mao C, Ye R, Wang M, Pen L, Dubeau L, Groshen S, Hofman FM, Lee AS
Critical role of the stress chaperone GRP78/BiP in tumor proliferation, survival, and tumor angiogenesis in transgene-induced mammary tumor development.
Cancer Res 68: 498-505 (2008)
PM ID: 18199545
12: Plikus MV, Mayer JA, de la Cruz D, Baker RE, Maini PK, Maxson R, Chuong CM
Cyclic dermal BMP signalling regulates stem cell activation during hair regeneration.
Nature 451: 340-4 (2008)
PM ID: 18202659 PMC2696201 NIHMS110153
13: Qiao R, Yan W, Clavijo CA, Mehrian-Shai R, Zhong Q, Kim KJ, Ann DK, Crandall ED, Borok Z
Effects of KGF on alveolar epithelial cell transdifferentiation are mediated by JNK signaling.
Am J Respir Cell Mol Biol 38: 239-46 (2008)
PM ID: 17872496 PMC2214671
14: Kang GH, Lee SY, Cho NY, Gandamihardja TA, Long TI, Weisenberger DJ, Campan M, Laird PW
DNA methylation profiles of gastric carcinoma characterized by quantitative DNA methylation analysis.
Lab Invest 88: 161-70 (2008)
PM ID: 18158559
15: Ku B, Woo JS, Liang C, Lee KH, Hong HS, E X, Kim KS, Jung JU, Oh BH
Structural and biochemical bases for the inhibition of autophagy and apoptosis by viral BCL-2 of murine gamma-herpesvirus 68.
PLoS Pathog 4: e25 (2008)
PM ID: 18248095 PMC2222952
16: Talbot SG, Mehrara BJ, Disa JJ, Wong AK, Pusic A, Cordeiro PG, Athanasian EA
Soft-tissue coverage of the hand following sarcoma resection.
Plast Reconstr Surg 121: 534-43 (2008)
PM ID: 18300973
17: Hacia JG, Lee CC, Jimenez DF, Karaman MW, Ho VV, Siegmund KD, Tarantal AF
Age-related gene expression profiles of rhesus monkey bone marrow-derived mesenchymal stem cells.
J Cell Biochem 103: 1198-210 (2008)
PM ID: 17685434
18: Bates SR, Tao JQ, Yu KJ, Borok Z, Crandall ED, Collins HL, Rothblat GH
Expression and biological activity of ABCA1 in alveolar epithelial cells.
Am J Respir Cell Mol Biol 38: 283-92 (2008)
PM ID: 17884990 PMC2258448
19: Collins RE, Northrop JP, Horton JR, Lee DY, Zhang XK, Stallcup MR, Cheng X
The ankyrin repeats of G9a and GLP histone methyltransferases are mono- and dimethyllysine binding modules.
Nat Struct Mol Biol 15: 245-50 (2008)
PM ID: 18264113 PMC2586904 NIHMS75647
20: Uchiyama T, Fujita T, Gukasyan HJ, Kim KJ, Borok Z, Crandall ED, Lee VH
Functional characterization and cloning of amino acid transporter B(0,+) (ATB(0,+)) in primary cultured rat pneumocytes.
J Cell Physiol 214: 645-54 (2008)
PM ID: 17960566
21: Pohl A, Lurje G, Kahn M, Lenz HJ
Stem cells in colon cancer.
Clin Colorectal Cancer 7: 92-8 (2008)
PM ID: 18501067
22: Schönmeyr BH, Wong AK, Li S, Gewalli F, Cordiero PG, Mehrara BJ
Treatment of hydroxyapatite scaffolds with fibronectin and fetal calf serum increases osteoblast adhesion and proliferation in vitro.
Plast Reconstr Surg 121: 751-62 (2008)
PM ID: 18317125
23: Takamori K, Hosokawa R, Xu X, Deng X, Bringas P, Chai Y
Epithelial fibroblast growth factor receptor 1 regulates enamel formation.
J Dent Res 87: 238-43 (2008)
PM ID: 18296607
24: Kim KJ, Choi J, Heo K, Kim HJ, Levens D, Kohno K, Johnson EM, Brock HW, An W
Isolation and characterization of a novel H1.2 complex that acts as a repressor of p53-mediated transcription.
J Biol Chem 283: 9113-26 (2008)
PM ID: 18258596 PMC2431041
25: Heo K, Kim HJ, Choi SH, Choi J, Kim KJ, Gu J, Lieber MR, Yang AS, An W
FACT-mediated exchange of histone variant H2AX regulated by phosphorylation of H2AX and ADP-ribosylation of Spt16.
Mol Cell 30: 86-97 (2008)
PM ID: 18406329
26: Johnson DL, Johnson SA
Cell biology. RNA metabolism and oncogenesis.
Science 320: 461-2 (2008)
PM ID: 18436765
27: Wong AK, Schonmeyr B, Schonmyer BH, Schonmeyer BH, Singh P, Carlson DL, Li S, Mehrara BJ
Histologic analysis of angiogenesis and lymphangiogenesis in acellular human dermis.
Plast Reconstr Surg 121: 1144-52 (2008)
PM ID: 18349631
28: Pike BL, Greiner TC, Wang X, Weisenburger DD, Hsu YH, Renaud G, Wolfsberg TG, Kim M, Weisenberger DJ, Siegmund KD, Ye W, Groshen S, Mehrian-Shai R, Delabie J, Chan WC, Laird PW, Hacia JG
DNA methylation profiles in diffuse large B-cell lymphoma and their relationship to gene expression status.
Leukemia 22: 1035-43 (2008)
PM ID: 18288132 PMC2654231 NIHMS97202
29: Cheng CF, Fan J, Fedesco M, Guan S, Li YT, Bandyopadhyay B, Bright AM, Yerushalmi D, Liang M, Chen M, Han YP, Woodley DT, Li W
Transforming growth factor alpha (TGFalpha)-stimulated secretion of HSP90alpha: using the receptor LRP-1/CD91 to promote human skin cell migration against a TGFbeta-rich environment during wound healing.
Mol Cell Biol 28: 3344-58 (2008)
PM ID: 18332123 PMC2423165
30: Ku B, Woo JS, Liang C, Lee KH, Jung JU, Oh BH
An insight into the mechanistic role of Beclin 1 and its inhibition by prosurvival Bcl-2 family proteins.
Autophagy 4: 519-20 (2008)
PM ID: 18334862
31: Gopalakrishna R, Gundimeda U, Schiffman JE, McNeill TH
A direct redox regulation of protein kinase C isoenzymes mediates oxidant-induced neuritogenesis in PC12 cells.
J Biol Chem 283: 14430-44 (2008)
PM ID: 18375950 PMC2386917 NIHMS48661
32: Zhou B, Zhong Q, Minoo P, Li C, Ann DK, Frenkel B, Morrisey EE, Crandall ED, Borok Z
Foxp2 inhibits Nkx2.1-mediated transcription of SP-C via interactions with the Nkx2.1 homeodomain.
Am J Respir Cell Mol Biol 38: 750-8 (2008)
PM ID: 18239190 PMC2396252
33: Patel LN, Uchiyama T, Kim KJ, Borok Z, Crandall ED, Shen WC, Lee VH
Molecular and functional expression of multidrug resistance-associated protein-1 in primary cultured rat alveolar epithelial cells.
J Pharm Sci 97: 2340-9 (2008)
PM ID: 17854063
34: Yacobi NR, Demaio L, Xie J, Hamm-Alvarez SF, Borok Z, Kim KJ, Crandall ED
Polystyrene nanoparticle trafficking across alveolar epithelium.
Nanomedicine 4: 139-45 (2008)
PM ID: 18375191
35: Chu MW, Siegmund KD, Hao QL, Crooks GM, Tavaré S, Shibata D
Inferring relative numbers of human leucocyte genome replications.
Br J Haematol 141: 862-71 (2008)
PM ID: 18410448
36: Woiwode A, Johnson SA, Zhong S, Zhang C, Roeder RG, Teichmann M, Johnson DL
PTEN represses RNA polymerase III-dependent transcription by targeting the TFIIIB complex.
Mol Cell Biol 28: 4204-14 (2008)
PM ID: 18391023 PMC2423115
37: Woodley DT, Hou Y, Martin SE, Li W, Chen M
Characterization of molecular mechanisms underlying mutations in dystrophic epidermolysis bullosa using site-directed mutagenesis.
J Biol Chem 283: 17838-45 (2008)
PM ID: 18450758 PMC2440610
38: Johnson SA, Dubeau L, Johnson DL
Enhanced RNA polymerase III-dependent transcription is required for oncogenic transformation.
J Biol Chem 283: 19184-91 (2008)
PM ID: 18456653 PMC2443659
39: Liang C, E X, Jung JU
Downregulation of autophagy by herpesvirus Bcl-2 homologs.
Autophagy 4: 268-72 (2008)
PM ID: 17993780
40: Kalakonda N, Fischle W, Boccuni P, Gurvich N, Hoya-Arias R, Zhao X, Miyata Y, Macgrogan D, Zhang J, Sims JK, Rice JC, Nimer SD
Histone H4 lysine 20 monomethylation promotes transcriptional repression by L3MBTL1.
Oncogene 27: 4293-304 (2008)
PM ID: 18408754 PMC2742506 NIHMS124782
41: Houston SI, McManus KJ, Adams MM, Sims JK, Carpenter PB, Hendzel MJ, Rice JC
Catalytic function of the PR-Set7 histone H4 lysine 20 monomethyltransferase is essential for mitotic entry and genomic stability.
J Biol Chem 283: 19478-88 (2008)
PM ID: 18480059 PMC2443654
42: Sims JK, Rice JC
PR-Set7 establishes a repressive trans-tail histone code that regulates differentiation.
Mol Cell Biol 28: 4459-68 (2008)
PM ID: 18474616 PMC2447116
43: Yuan JM, Chan KK, Coetzee GA, Castelao JE, Watson MA, Bell DA, Wang RH, Yu MC
Genetic determinants in the metabolism of bladder carcinogens in relation to risk of bladder cancer.
Carcinogenesis 29: 1386-93 (2008)
PM ID: 18544563 PMC2720058 NIHMS104621
44: Zhou B, Ann DK, Flodby P, Minoo P, Liebler JM, Crandall ED, Borok Z
Rat aquaporin-5 4.3-kb 5'-flanking region differentially regulates expression in salivary gland and lung in vivo.
Am J Physiol Cell Physiol 295: C111-20 (2008)
PM ID: 18448628 PMC2493550
45: Liang C, Lee JS, Inn KS, Gack MU, Li Q, Roberts EA, Vergne I, Deretic V, Feng P, Akazawa C, Jung JU
Beclin1-binding UVRAG targets the class C Vps complex to coordinate autophagosome maturation and endocytic trafficking.
Nat Cell Biol 10: 776-87 (2008)
PM ID: 18552835
46: Lyu J, Yamamoto V, Lu W
Cleavage of the Wnt receptor Ryk regulates neuronal differentiation during cortical neurogenesis.
Dev Cell 15: 773-80 (2008)
PM ID: 19000841
47: Schönmeyr BH, Wong AK, Soares M, Fernandez J, Clavin N, Mehrara BJ
Ionizing radiation of mesenchymal stem cells results in diminution of the precursor pool and limits potential for multilineage differentiation.
Plast Reconstr Surg 122: 64-76 (2008)
PM ID: 18594388
48: Chen HM, Zhuang FF, Liu YH, Xu B, Del Moral PM, Deng WT, Chai Y, Kolb M, Gauldie J, Warburton D, Moses HL, Shi W
TGF-beta receptor II in epithelia versus mesenchyme plays distinct roles in the developing lung.
Eur Respir J 32: 285-95 (2008)
PM ID: 18321928
49: Cheng CF, Fan J, Bandyopahdhay B, Mock D, Guan S, Chen M, Woodley DT, Li W
Profiling motility signal-specific genes in primary human keratinocytes.
J Invest Dermatol 128: 1981-90 (2008)
PM ID: 18323786
50: Bahhady R, Kim KJ, Borok Z, Crandall ED, Shen WC
Characterization of protein factor(s) in rat bronchoalveolar lavage fluid that enhance insulin transport via transcytosis across primary rat alveolar epithelial cell monolayers.
Eur J Pharm Biopharm 69: 808-16 (2008)
PM ID: 18406118
51: Weisenberger DJ, Trinh BN, Campan M, Sharma S, Long TI, Ananthnarayan S, Liang G, Esteva FJ, Hortobagyi GN, McCormick F, Jones PA, Laird PW
DNA methylation analysis by digital bisulfite genomic sequencing and digital MethyLight.
Nucleic Acids Res 36: 4689-98 (2008)
PM ID: 18628296 PMC2504308
52: Sir D, Liang C, Chen WL, Jung JU, Ou JH
Perturbation of autophagic pathway by hepatitis C virus.
Autophagy 4: 830-1 (2008)
PM ID: 18635950 PMC2574555 NIHMS60148
53: Liang C, Sir D, Lee SY, Ou JH, Jung JU
Beyond autophagy: the role of UVRAG in membrane trafficking.
Autophagy 4: 817-20 (2008)
PM ID: 18612260
54: Byun HM, Choi SH, Laird PW, Trinh BN, Siddiqui MA, Marquez VE, Yang AS
2'-Deoxy-N4-[2-(4-nitrophenyl)ethoxycarbonyl]-5-azacytidine: a novel inhibitor of DNA methyltransferase that requires activation by human carboxylesterase 1.
Cancer Lett 266: 238-48 (2008)
PM ID: 18499340 PMC2528876 NIHMS57985
55: Julien KR, Sumita M, Chen PH, Laird-Offringa IA, Hoogstraten CG
Conformationally restricted nucleotides as a probe of structure-function relationships in RNA.
RNA 14: 1632-43 (2008)
PM ID: 18596252 PMC2491483
56: Virrey JJ, Guan S, Li W, Schönthal AH, Chen TC, Hofman FM
Increased survivin expression confers chemoresistance to tumor-associated endothelial cells.
Am J Pathol 173: 575-85 (2008)
PM ID: 18599610 PMC2475793
57: Virrey JJ, Dong D, Stiles C, Patterson JB, Pen L, Ni M, Schönthal AH, Chen TC, Hofman FM, Lee AS
Stress chaperone GRP78/BiP confers chemoresistance to tumor-associated endothelial cells.
Mol Cancer Res 6: 1268-75 (2008)
PM ID: 18708359 PMC2593417 NIHMS72229
58: Xing Y, Li C, Hu L, Tiozzo C, Li M, Chai Y, Bellusci S, Anderson SA, Minoo P
Mechanisms of TGFbeta inhibition of LUNG endodermal morphogenesis: the role of TbetaRII, Smads, Nkx2.1 and Pten.
Dev Biol 320: 340-50 (2008)
PM ID: 18602626 PMC2597224 NIHMS65745
59: Xu X, Han J, Ito Y, Bringas P, Deng C, Chai Y
Ectodermal Smad4 and p38 MAPK are functionally redundant in mediating TGF-beta/BMP signaling during tooth and palate development.
Dev Cell 15: 322-9 (2008)
PM ID: 18694570 PMC2610417 NIHMS66185
60: Liebler JM, Lutzko C, Banfalvi A, Senadheera D, Aghamohammadi N, Crandall ED, Borok Z
Retention of human bone marrow-derived cells in murine lungs following bleomycin-induced lung injury.
Am J Physiol Lung Cell Mol Physiol 295: L285-92 (2008)
PM ID: 18515407 PMC2519849
61: Douglas D, Hsu JH, Hung L, Cooper A, Abdueva D, van Doorninck J, Peng G, Shimada H, Triche TJ, Lawlor ER
BMI-1 promotes ewing sarcoma tumorigenicity independent of CDKN2A repression.
Cancer Res 68: 6507-15 (2008)
PM ID: 18701473 PMC2570201 NIHMS56191
62: Meyer JS, Nadel HR, Marina N, Womer RB, Brown KL, Eary JF, Gorlick R, Grier HE, Randall RL, Lawlor ER, Lessnick SL, Schomberg PJ, Kailo MD
Imaging guidelines for children with Ewing sarcoma and osteosarcoma: a report from the Children's Oncology Group Bone Tumor Committee.
Pediatr Blood Cancer 51: 163-70 (2008)
PM ID: 18454470
63: Marson A, Foreman R, Chevalier B, Bilodeau S, Kahn M, Young RA, Jaenisch R
Wnt signaling promotes reprogramming of somatic cells to pluripotency.
Cell Stem Cell 3: 132-5 (2008)
PM ID: 18682236
64: Kim JH, Yang CK, Heo K, Roeder RG, An W, Stallcup MR
CCAR1, a key regulator of mediator complex recruitment to nuclear receptor transcription complexes.
Mol Cell 31: 510-9 (2008)
PM ID: 18722177 PMC2562329 NIHMS64408
65: Wolff EM, Liang G, Cortez CC, Tsai YC, Castelao JE, Cortessis VK, Tsao-Wei DD, Groshen S, Jones PA
RUNX3 methylation reveals that bladder tumors are older in patients with a history of smoking.
Cancer Res 68: 6208-14 (2008)
PM ID: 18676844 PMC2536768 NIHMS53732
66: American Association for Cancer Research Human Epigenome Task Force(Dr. Jones PA) , American Association for Cancer Research Human Epigenome Task Force(Dr. Laird PW) , European Union, Network of Excellence, Scientific Advisory Board
Moving AHEAD with an international human epigenome project.
Nature 454: 711-5 (2008)
PM ID: 18685699
67: Li JZ, Ni M, Lee B, Barron E, Hinton DR, Lee AS
The unfolded protein response regulator GRP78/BiP is required for endoplasmic reticulum integrity and stress-induced autophagy in mammalian cells.
Cell Death Differ 15: 1460-71 (2008)
PM ID: 18551133 PMC2758056 NIHMS129474
68: Coles EG, Lawlor ER, Bronner-Fraser M
EWS-FLI1 causes neuroepithelial defects and abrogates emigration of neural crest stem cells.
Stem Cells 26: 2237-44 (2008)
PM ID: 18556509
69: Yoo CB, Chuang JC, Byun HM, Egger G, Yang AS, Dubeau L, Long TI, Laird PW, Marquez VE, Jones PA
Long-term epigenetic therapy with oral zebularine has minimal side effects and prevents intestinal tumors in mice.
Cancer Prev Res (Phila Pa) 1: 233-40 (2008)
PM ID: 19138966
70: Gal-Yam EN, Egger G, Iniguez L, Holster H, Einarsson S, Zhang XK, Lin JC, Liang G, Jones PA, Tanay A
Frequent switching of Polycomb repressive marks and DNA hypermethylation in the PC3 prostate cancer cell line.
Proc Natl Acad Sci U S A 105: 12979-84 (2008)
PM ID: 18753622 PMC2529074
71: Lopes EC, Valls E, Figueroa ME, Mazur A, Meng FG, Chiosis G, Laird PW, Schreiber-Agus N, Greally JM, Prokhortchouk E, Melnick A
Kaiso contributes to DNA methylation-dependent silencing of tumor suppressor genes in colon cancer cell lines.
Cancer Res 68: 7258-63 (2008)
PM ID: 18794111
72: Robinson PJ, An W, Routh A, Martino F, Chapman L, Roeder RG, Rhodes D
30 nm chromatin fibre decompaction requires both H4-K16 acetylation and linker histone eviction.
J Mol Biol 381: 816-25 (2008)
PM ID: 18653199
73: Valamehr B, Jonas SJ, Polleux J, Qiao R, Guo S, Gschweng EH, Stiles B, Kam K, Luo TJ, Witte ON, Liu X, Dunn B, Wu H
Hydrophobic surfaces for enhanced differentiation of embryonic stem cell-derived embryoid bodies.
Proc Natl Acad Sci U S A 105: 14459-64 (2008)
PM ID: 18791068 PMC2567159
74: Cancer Genome Atlas Research Network
Comprehensive genomic characterization defines human glioblastoma genes and core pathways.
Nature 455: 1061-8 (2008)
PM ID: 18772890 PMC2671642 NIHMS68048
75: Gack MU, Kirchhofer A, Shin YC, Inn KS, Liang C, Cui S, Myong S, Ha TT, Hopfner KP, Jung JU
Roles of RIG-I N-terminal tandem CARD and splice variant in TRIM25-mediated antiviral signal transduction.
Proc Natl Acad Sci U S A 105: 16743-8 (2008)
PM ID: 18948594 PMC2575490
76: Fromm JA, Johnson SA, Johnson DL
Epidermal growth factor receptor 1 (EGFR1) and its variant EGFRvIII regulate TATA-binding protein expression through distinct pathways.
Mol Cell Biol 28: 6483-95 (2008)
PM ID: 18710943 PMC2577416
77: Pregizer S, Baniwal SK, Yan X, Borok Z, Frenkel B
Progressive recruitment of Runx2 to genomic targets despite decreasing expression during osteoblast differentiation.
J Cell Biochem 105: 965-70 (2008)
PM ID: 18821584 PMC2591066 NIHMS75367
78: Zhou B, Francis TA, Yang HT, Tseng W, Zhong Q, Frenkel B, Morrisey EE, Ann DK, Minoo P, Crandall ED, Borok Z
GATA-6 mediates transcriptional activation of aquaporin-5 through interactions with Sp1.
Am J Physiol Cell Physiol 295: C1141-50 (2008)
PM ID: 18768929 PMC2584994
79: Poynter JN, Siegmund KD, Weisenberger DJ, Long TI, Thibodeau SN, Lindor NM, Young JP, Jenkins MA, Hopper JL, Baron JA, Buchanan D, Casey GR, Levine AJ, Le Marchand L, Gallinger S, Bapat B, Potter JD, Newcomb PA, Haile RW, Laird PW, Colon Cancer Family Registry Investigators
Molecular characterization of MSI-H colorectal cancer by MLHI promoter methylation, immunohistochemistry, and mismatch repair germline mutation screening.
Cancer Epidemiol Biomarkers Prev 17: 3208-15 (2008)
PM ID: 18990764 PMC2628332 NIHMS80565
80: McIntosh M, Anderson GL, Drescher C, Hanash S, Urban N, Brown PO, Gambhir SS, Coukos G, Laird PW, Nelson B, Palmer C
Ovarian cancer early detection claims are biased.
Clin Cancer Res 14: 7574; author reply 7577-9 (2008)
PM ID: 18948385
81: Mayer JA, Foley J, de la Cruz D, Chuong CM, Widelitz RB
Conversion of the nipple to hair-bearing epithelia by lowering bone morphogenetic protein pathway activity at the dermal-epidermal interface.
Am J Pathol 173: 1339-48 (2008)
PM ID: 18832580 PMC2570124
82: Cortez CC, Jones PA
Chromatin, cancer and drug therapies.
Mutat Res 647: 44-51 (2008)
PM ID: 18691602 PMC2631123 [Available on 12/01/09] NIHMS81512 [Available on 12/01/09]
83: Khalid O, Baniwal SK, Purcell DJ, Leclerc N, Gabet Y, Stallcup MR, Coetzee GA, Frenkel B
Modulation of Runx2 activity by estrogen receptor-alpha: implications for osteoporosis and breast cancer.
Endocrinology 149: 5984-95 (2008)
PM ID: 18755791 PMC2613062 [Available on 12/01/09]
84: Fu Y, Wey S, Wang M, Ye R, Liao CP, Roy-Burman P, Lee AS
Pten null prostate tumorigenesis and AKT activation are blocked by targeted knockout of ER chaperone GRP78/BiP in prostate epithelium.
Proc Natl Acad Sci U S A 105: 19444-9 (2008)
PM ID: 19033462 PMC2614780
85: Yeung BH, Kwan BW, He QY, Lee AS, Liu JF, Wong AS
Glucose-regulated protein 78 as a novel effector of BRCA1 for inhibiting stress-induced apoptosis.
Oncogene 27: 6782-9 (2008)
PM ID: 18776923
86: Yoo CB, Valente R, Congiatu C, Gavazza F, Angel A, Siddiqui MA, Jones PA, McGuigan C, Marquez VE
Activation of p16 gene silenced by DNA methylation in cancer cells by phosphoramidate derivatives of 2'-deoxyzebularine.
J Med Chem 51: 7593-601 (2008)
PM ID: 19006382 PMC2659950 [Available on 12/11/09] NIHMS90725 [Available on 12/11/09]
87: Li P, Tong C, Mehrian-Shai R, Jia L, Wu N, Yan Y, Maxson RE, Schulze EN, Song H, Hsieh CL, Pera MF, Ying QL
Germline competent embryonic stem cells derived from rat blastocysts.
Cell 135: 1299-310 (2008)
PM ID: 19109898 PMC2735113 NIHMS131481
88: Li M, Li C, Liu YH, Xing Y, Hu L, Borok Z, Kwong KY, Minoo P
Mesodermal deletion of transforming growth factor-beta receptor II disrupts lung epithelial morphogenesis: cross-talk between TGF-beta and Sonic hedgehog pathways.
J Biol Chem 283: 36257-64 (2008)
PM ID: 18990706 PMC2605990 [Available on 12/26/09]
89: Liang C, Lee JS, Jung JU
Immune evasion in Kaposi's sarcoma-associated herpes virus associated oncogenesis.
Semin Cancer Biol 18: 423-36 (2008)
PM ID: 18948197
90: Gundimeda U, Schiffman JE, Chhabra D, Wong J, Wu A, Gopalakrishna R
Locally generated methylseleninic acid induces specific inactivation of protein kinase C isoenzymes: relevance to selenium-induced apoptosis in prostate cancer cells.
J Biol Chem 283: 34519-31 (2008)
PM ID: 18922790
91: Tsou JA, Kazarian M, Patel AV, Galler JS, Laird-Offringa IA, Carpenter CL, London SJ
Low level anti-Hu reactivity: A risk marker for small cell lung cancer?
Cancer Detect Prev 32: 292-9 (2009)
PM ID: 19070439
92: Haiman CA, Garcia RR, Hsu CP, Xia L, Ha H, Sheng X, Le Marchand L, Kolonel LN, Henderson BE, Stallcup MR, Greene GL, Press MF
Screening and association testing of common coding variation in steroid hormone receptor co-activator and co-repressor genes in relation to breast cancer risk: the Multiethnic Cohort.
BMC Cancer 9: 43 (2009)
PM ID: 19183483 PMC2637888
93: Plikus MV, Widelitz RB, Maxson R, Chuong CM
Analyses of regenerative wave patterns in adult hair follicle populations reveal macro-environmental regulation of stem cell activity.
Int J Dev Biol 53: 857-68 (2009)
PM ID: 19378257 PMC2759942 NIHMS131491
94: Campan M, Weisenberger DJ, Trinh BN, Laird PW
MethyLight.
Methods Mol Biol 507: 325-37 (2009)
PM ID: 18987824
95: Noh T, Gabet Y, Cogan JP, Shi Y, Tank A, Sasaki T, Criswell B, Dixon A, Lee CT, Tam J, Kohler T, Segev E, Kockeritz L, Woodgett JR, Müller R, Chai Y, Smith E, Bab I, Frenkel B
Lef1 haploinsufficient mice display a low turnover and low bone mass phenotype in a gender- and age-specific manner.
PLoS One 4: e5438 (2009)
PM ID: 19412553 PMC2673053
96: Zhou L, Yan C, Gieling RG, Kida Y, Garner WL, Li W, Han YP
Tumor necrosis factor-alpha induced expression of matrix metalloproteinase-9 through p21-activated kinase-1.
BMC Immunol 10: 15 (2009)
PM ID: 19298660 PMC2669056
97: Toleno DM, Renaud G, Wolfsberg TG, Islam M, Wildman DE, Siegmund KD, Hacia JG
Development and evaluation of new mask protocols for gene expression profiling in humans and chimpanzees.
BMC Bioinformatics 10: 77 (2009)
PM ID: 19265541 PMC2660304
98: Ni M, Zhou H, Wey S, Baumeister P, Lee AS
Regulation of PERK signaling and leukemic cell survival by a novel cytosolic isoform of the UPR regulator GRP78/BiP.
PLoS One 4: e6868 (2009)
PM ID: 19718440 PMC2729930
99: Joo J, Christensen L, Warner KL, States L, Kang HG, Vo K, Lawlor ER, May WA
GLI1 is a central mediator of EWS/FLI1 signaling in Ewing tumors.
PLoS One 4: e7608 (2009)
PM ID: 19859563 PMC2763206
100: Hinoue T, Weisenberger DJ, Pan F, Campan M, Kim M, Young J, Whitehall VL, Leggett BA, Laird PW
Analysis of the association between CIMP and BRAF in colorectal cancer by DNA methylation profiling.
PLoS One 4: e8357 (2009)
PM ID: 20027224 PMC2791229
101: Shtir C, Pique-Regi R, Siegmund K, Morrison J, Schumacher F, Marjoram P
Copy number variation in the Framingham Heart Study.
BMC Proc 3 Suppl 7: S133 (2009)
PM ID: 20018000 PMC2795907
102: Borok Z
Role for alpha3 integrin in EMT and pulmonary fibrosis.
J Clin Invest 119: 7-10 (2009)
PM ID: 19104143
103: Youssef RF, Mitra AP, Bartsch G, Jones PA, Skinner DG, Cote RJ
Molecular targets and targeted therapies in bladder cancer management.
World J Urol 27: 9-20 (2009)
PM ID: 19039591
104: Chen JL, Lin HH, Kim KJ, Lin AH, Ou JH, Ann DK
PKC delta signaling: a dual role in regulating hypoxic stress-induced autophagy and apoptosis.
Autophagy 5: 244-6 (2009)
PM ID: 19098423 PMC2743529 NIHMS123596
105: Saito Y, Friedman JM, Chihara Y, Egger G, Chuang JC, Liang G
Epigenetic therapy upregulates the tumor suppressor microRNA-126 and its host gene EGFL7 in human cancer cells.
Biochem Biophys Res Commun 379: 726-31 (2009)
PM ID: 19116145
106: Zhang ZY, Lan Y, Chai Y, Jiang R
Antagonistic actions of Msx1 and Osr2 pattern mammalian teeth into a single row.
Science 323: 1232-4 (2009)
PM ID: 19251632 PMC2650836 [Available on 02/27/10] NIHMS88200 [Available on 02/27/10]
107: Chuong CM, Widelitz RB
The river of stem cells.
Cell Stem Cell 4: 100-2 (2009)
PM ID: 19200797
108: Rountree CB, Ding W, He L, Stiles B
Expansion of CD133-expressing liver cancer stem cells in liver-specific phosphatase and tensin homolog deleted on chromosome 10-deleted mice.
Stem Cells 27: 290-9 (2009)
PM ID: 19008348
109: Wong AK, Mei L, Soares MA, Schönmeyr BH, Mehrara BJ
Radioprotection of osteoblasts by a fractionated dose regimen and amifostine.
Plast Reconstr Surg 123: 104S-13S (2009)
PM ID: 19182669
110: Asahina K, Tsai SY, Li P, Ishii M, Maxson RE, Sucov HM, Tsukamoto H
Mesenchymal origin of hepatic stellate cells, submesothelial cells, and perivascular mesenchymal cells during mouse liver development.
Hepatology 49: 998-1011 (2009)
PM ID: 19085956 PMC2673117 [Available on 03/01/10] NIHMS98872 [Available on 03/01/10]
111: Jariwala U, Cogan JP, Jia L, Frenkel B, Coetzee GA
Inhibition of AR-mediated transcription by binding of Oct1 to a motif enriched in AR-occupied regions.
Prostate 69: 392-400 (2009)
PM ID: 19058140 PMC2743387 NIHMS129716
112: Joshi AD, Corral R, Siegmund KD, Haile RW, Le Marchand L, Martínez ME, Ahnen DJ, Sandler RS, Lance P, Stern MC
Red meat and poultry intake, polymorphisms in the nucleotide excision repair and mismatch repair pathways and colorectal cancer risk.
Carcinogenesis 30: 472-9 (2009)
PM ID: 19029193 PMC2722151 [Available on 03/01/10]
113: Rich RL, Papalia GA, Flynn PJ, Furneisen J, Quinn JA, Klein JS, Katsamba PS, Waddell MB, Scott ML, Thompson JR, Berlier J, Corry S, Baltzinger M, Zeder-Lutz G, Schoenemann A, Clabbers A, Wieckowski S, Murphy MM, Page P, Ryan TE, Duffner J, Ganguly T, Corbin J, Gautam S, Anderluh G, Bavdek A, Reichmann D, Yadav SP, Hommema E, Pol E, Drake A, Klakamp S, Chapman T, Kernaghan D, Miller KD, Schuman J, Lindquist KC, Herlihy K, Murphy MB, Bohnsack R, Andrien B, Brandani P, Terwey D, Millican R, Darling RJ, Wang L, Carter Q, Dotzlaf J, Lopez-Sagaseta J, Campbell I, Torreri P, Hoos S, England P, Liu Y, Abdiche Y, Malashock D, Pinkerton A, Wong MM, Lafer E, Hinck C, Thompson K, Primo CD, Joyce A, Brooks J, Torta F, Bagge Hagel AB, Krarup J, Pass J, Ferreira MA, Shikov S, Mikolajczyk M, Abe Y, Barbato G, Giannetti AM, Krishnamoorthy G, Beusink B, Satpaev D, Tsang T, Fang E, Partridge J, Brohawn S, Horn J, Pritsch O, Obal G, Nilapwar S, Busby B, Gutierrez-Sanchez G, Gupta RD, Canepa S, Witte K, Nikolovska-Coleska Z, Cho YH, D'Agata R, Schlick K, Calvert R, Munoz EM, Hernaiz MJ, Bravman T, Dines M, Yang MH, Puskas A, Boni E, Li JZ, Wear M, Grinberg A, Baardsnes J, Dolezal O, Gainey M, Anderson H, Peng J, Lewis MA, Spies P, Trinh Q, Bibikov S, Raymond J, Yousef M, Chandrasekaran V, Feng Y, Emerick A, Mundodo S, Guimaraes R, McGirr K, Li YJ, Hughes H, Mantz H, Skrabana R, Witmer M, Ballard J, Martin L, Skladal P, Korza G, Laird-Offringa IA, Lee CS, Khadir A, Podlaski F, Neuner P, Rothacker J, Rafique A, Dankbar N, Kainz P, Gedig E, Vuyisich M, Boozer C, Ly N, Toews M, Uren A, Kalyuzhniy O, Lewis KD, Chomey E, Pak BJ, Myszka DG
A global benchmark study using affinity-based biosensors.
Anal Biochem 386: 194-216 (2009)
PM ID: 19133223
114: Ting MC, Wu NL, Roybal PG, Sun J, Liu L, Yen Y, Maxson RE
EphA4 as an effector of Twist1 in the guidance of osteogenic precursor cells during calvarial bone growth and in craniosynostosis.
Development 136: 855-64 (2009)
PM ID: 19201948 PMC2685950 [Available on 03/01/10] NIHMS131479 [Available on 03/01/10]
115: Friedman JM, Liang G, Liu CC, Wolff EM, Tsai YC, Ye W, Zhou XJ, Jones PA
The putative tumor suppressor microRNA-101 modulates the cancer epigenome by repressing the polycomb group protein EZH2.
Cancer Res 69: 2623-9 (2009)
PM ID: 19258506
116: Siegmund KD, Marjoram P, Woo YJ, Tavaré S, Shibata D
Inferring clonal expansion and cancer stem cell dynamics from DNA methylation patterns in colorectal cancers.
Proc Natl Acad Sci U S A 106: 4828-33 (2009)
PM ID: 19261858 PMC2651202
117: Woo YJ, Siegmund KD, Tavaré S, Shibata D
Older individuals appear to acquire mitotically older colorectal cancers.
J Pathol 217: 483-8 (2009)
PM ID: 19165870
118: Bapat B, Lindor NM, Baron JA, Siegmund KD, Li L, Zheng YT, Haile R, Gallinger S, Jass JR, Young JP, Cotterchio M, Jenkins MA, Grove J, Casey GR, Thibodeau SN, Bishop DT, Hopper JL, Ahnen DJ, Newcomb PA, Le Marchand L, Potter JD, Seminara D, Colon Cancer Family Registry
The association of tumor microsatellite instability phenotype with family history of colorectal cancer.
Cancer Epidemiol Biomarkers Prev 18: 967-75 (2009)
PM ID: 19258475 PMC2763617 [Available on 03/01/10] NIHMS139549 [Available on 03/01/10]
119: Shi SR, Chai Y, Slavkin HC
Emerging opportunities for the next generation of dental implants?
Dent Today 28: 98-9 (2009)
PM ID: 19323323
120: Patel LN, Wang JG, Kim KJ, Borok Z, Crandall ED, Shen WC
Conjugation with cationic cell-penetrating peptide increases pulmonary absorption of insulin.
Mol Pharm 6: 492-503 (2009)
PM ID: 19228019
121: Lyu J, Wesselschmidt RL, Lu W
Cdc37 regulates Ryk signaling by stabilizing the cleaved Ryk intracellular domain.
J Biol Chem 284: 12940-8 (2009)
PM ID: 19269974
122: Lee YH, Stallcup MR
Minireview: protein arginine methylation of nonhistone proteins in transcriptional regulation.
Mol Endocrinol 23: 425-33 (2009)
PM ID: 19164444 PMC2667706 [Available on 04/01/10]
123: Aparicio A, North B, Barske L, Wang X, Bollati V, Weisenberger D, Yoo C, Tannir N, Horne E, Groshen S, Jones P, Yang A, Issa JP
LINE-1 methylation in plasma DNA as a biomarker of activity of DNA methylation inhibitors in patients with solid tumors.
Epigenetics 4: 176-84 (2009)
PM ID: 19421002
124: Berman BP, Weisenberger DJ, Laird PW
Locking in on the human methylome.
Nat Biotechnol 27: 341-2 (2009)
PM ID: 19352369
125: Chung IH, Yamaza T, Zhao H, Choung PH, Shi SR, Chai Y
Stem cell property of postmigratory cranial neural crest cells and their utility in alveolar bone regeneration and tooth development.
Stem Cells 27: 866-77 (2009)
PM ID: 19350689
126: Stiles BL
Phosphatase and tensin homologue deleted on chromosome 10: extending its PTENtacles.
Int J Biochem Cell Biol 41: 757-61 (2009)
PM ID: 18950730
127: Sohn KJ, Jang H, Campan M, Weisenberger DJ, Dickhout J, Wang YC, Cho RC, Yates Z, Lucock M, Chiang EP, Austin RC, Choi SW, Laird PW, Kim YI
The methylenetetrahydrofolate reductase C677T mutation induces cell-specific changes in genomic DNA methylation and uracil misincorporation: a possible molecular basis for the site-specific cancer risk modification.
Int J Cancer 124: 1999-2005 (2009)
PM ID: 19123462 PMC2692263 [Available on 05/01/10] NIHMS99332 [Available on 05/01/10]
128: Kumar SR, Scehnet JS, Ley EJ, Singh J, Krasnoperov V, Liu R, Manchanda PK, Ladner RD, Hawes D, Weaver FA, Beart RW, Singh G, Nguyen C, Kahn M, Gill PS
Preferential induction of EphB4 over EphB2 and its implication in colorectal cancer progression.
Cancer Res 69: 3736-45 (2009)
PM ID: 19366806
129: Baumeister P, Dong D, Fu Y, Lee AS
Transcriptional induction of GRP78/BiP by histone deacetylase inhibitors and resistance to histone deacetylase inhibitor-induced apoptosis.
Mol Cancer Ther : (2009)
PM ID: 19417144
130: Berman BP, Frenkel B, Coetzee GA
Location, location, (ChIP-)location! Mapping chromatin landscapes one immunoprecipitation at a time.
J Cell Biochem 107: 1-5 (2009)
PM ID: 19308935 PMC2748114 [Available on 05/01/10] NIHMS136755 [Available on 05/01/10]
131: Woodley DT, Fan J, Cheng CF, Li YT, Chen M, Bu G, Li W
Participation of the lipoprotein receptor LRP1 in hypoxia-HSP90alpha autocrine signaling to promote keratinocyte migration.
J Cell Sci 122: 1495-8 (2009)
PM ID: 19383717 PMC2680098 [Available on 05/15/10]
132: Miranda TB, Cortez CC, Yoo CB, Liang G, Abe M, Kelly TK, Marquez VE, Jones PA
DZNep is a global histone methylation inhibitor that reactivates developmental genes not silenced by DNA methylation.
Mol Cancer Ther 8: 1579-88 (2009)
PM ID: 19509260
133: Demaio L, Tseng W, Balverde Z, Alvarez JR, Kim KJ, Kelley DG, Senior RM, Crandall ED, Borok Z
Characterization of mouse alveolar epithelial cell monolayers.
Am J Physiol Lung Cell Mol Physiol 296: L1051-8 (2009)
PM ID: 19329539 PMC2692796 [Available on 06/01/10]
134: Ou CY, Kim JH, Yang CK, Stallcup MR
Requirement of cell cycle and apoptosis regulator 1 for target gene activation by Wnt and beta-catenin and for anchorage-independent growth of human colon carcinoma cells.
J Biol Chem 284: 20629-37 (2009)
PM ID: 19520846 PMC2742827 [Available on 07/31/10]
135: Siegmund KD, Marjoram P, Tavaré S, Shibata D
Many colorectal cancers are "flat" clonal expansions.
Cell Cycle 8: 2187-93 (2009)
PM ID: 19556889
136: Li AY, Boo LM, Wang SY, Lin HH, Wang CC, Yen Y, Chen BP, Chen DJ, Ann DK
Suppression of nonhomologous end joining repair by overexpression of HMGA2.
Cancer Res 69: 5699-706 (2009)
PM ID: 19549901 PMC2737594 [Available on 07/15/10] NIHMS119606 [Available on 07/15/10]
137: Kim HJ, Heo K, Kim JH, Kim KJ, Choi J, An W
Requirement of histone methyltransferase SMYD3 for estrogen receptor-mediated transcription.
J Biol Chem 284: 19867-77 (2009)
PM ID: 19509295 PMC2740412 [Available on 07/24/10]
138: Baniwal SK, Khalid O, Sir D, Buchanan G, Coetzee GA, Frenkel B
Repression of Runx2 by androgen receptor (AR) in osteoblasts and prostate cancer cells: AR binds Runx2 and abrogates its recruitment to DNA.
Mol Endocrinol 23: 1203-14 (2009)
PM ID: 19389811 PMC2718746 [Available on 08/01/10]
139: Pomerantz MM, Ahmadiyeh N, Jia L, Herman P, Verzi MP, Doddapaneni H, Beckwith CA, Chan JA, Hills A, Davis M, Yao KL, Kehoe SM, Lenz HJ, Haiman CA, Yan C, Henderson BE, Frenkel B, Barretina J, Bass A, Tabernero J, Baselga J, Regan MM, Manak JR, Shivdasani R, Coetzee GA, Freedman ML
The 8q24 cancer risk variant rs6983267 shows long-range interaction with MYC in colorectal cancer.
Nat Genet 41: 882-4 (2009)
PM ID: 19561607 PMC2763485 [Available on 02/01/10] NIHMS120360 [Available on 02/01/10]
140: Guan S, Fan J, Han A, Chen M, Woodley DT, Li W
Non-compensating roles between Nckalpha and Nckbeta in PDGF-BB signaling to promote human dermal fibroblast migration.
J Invest Dermatol 129: 1909-20 (2009)
PM ID: 19242519
141: Choi SH, Worswick SD, Byun HM, Shear T, Soussa JC, Wolff EM, Douer D, Garcia-Manero G, Liang G, Yang AS
Changes in DNA methylation of tandem DNA repeats are different from interspersed repeats in cancer.
Int J Cancer 125: 723-9 (2009)
PM ID: 19437537
142: Friedman JM, Jones PA
MicroRNAs: critical mediators of differentiation, development and disease.
Swiss Med Wkly 139: 466-72 (2009)
PM ID: 19705306
143: Friedman JM, Jones PA, Liang G
The tumor suppressor microRNA-101 becomes an epigenetic player by targeting the polycomb group protein EZH2 in cancer.
Cell Cycle 8: 2313-4 (2009)
PM ID: 19625769
144: Jia L, Landan G, Pomerantz MM, Jaschek R, Herman P, Reich D, Yan C, Khalid O, Kantoff PW, Oh WK, Manak JR, Berman BP, Henderson BE, Frenkel B, Haiman CA, Freedman ML, Tanay A, Coetzee GA
Functional enhancers at the gene-poor 8q24 cancer-linked locus.
PLoS Genet 5: e1000597 (2009)
PM ID: 19680443 PMC2717370
145: Peters AA, Buchanan G, Ricciardelli C, Bianco-Miotto T, Centenera MM, Harris JM, Jindal S, Segara D, Jia L, Moore NL, Henshall SM, Birrell SN, Coetzee GA, Sutherland RL, Butler LM, Tilley WD
Androgen receptor inhibits estrogen receptor-alpha activity and is prognostic in breast cancer.
Cancer Res 69: 6131-40 (2009)
PM ID: 19638585
146: Li FP, Zeng B, Chai Y, Cai P, Fan C, Cheng T
The linker region of Smad2 mediates TGF-beta-dependent ERK2-induced collagen synthesis.
Biochem Biophys Res Commun 386: 289-93 (2009)
PM ID: 19465000
147: Zhong S, Johnson DL
The JNKs differentially regulate RNA polymerase III transcription by coordinately modulating the expression of all TFIIIB subunits.
Proc Natl Acad Sci U S A 106: 12682-7 (2009)
PM ID: 19620725 PMC2722300 [Available on 02/04/10]
148: Jiang X, Gwye Y, McKeown SJ, Bronner-Fraser M, Lutzko C, Lawlor ER
Isolation and characterization of neural crest stem cells derived from in vitro-differentiated human embryonic stem cells.
Stem Cells Dev 18: 1059-70 (2009)
PM ID: 19099373
149: Wang M, Wey S, Zhang Y, Ye R, Lee AS
Role of the unfolded protein response regulator GRP78/BiP in development, cancer, and neurological disorders.
Antioxid Redox Signal 11: 2307-16 (2009)
PM ID: 19309259
150: Bouazoune K, Miranda TB, Jones PA, Kingston RE
Analysis of individual remodeled nucleosomes reveals decreased histone-DNA contacts created by hSWI/SNF.
Nucleic Acids Res 37: 5279-94 (2009)
PM ID: 19567737 PMC2760786
151: Spektor TM, Rice JC
Identification and characterization of posttranslational modification-specific binding proteins in vivo by mammalian tethered catalysis.
Proc Natl Acad Sci U S A 106: 14808-13 (2009)
PM ID: 19706462
152: Dieli-Conwright CM, Spektor TM, Rice JC, Schroeder ET
Hormone therapy attenuates exercise-induced skeletal muscle damage in postmenopausal women.
J Appl Physiol 107: 853-8 (2009)
PM ID: 19574506
153: Willis BC, Borok Z
Epithelial-mesenchymal transition: potential role in obliterative bronchiolitis?
Thorax 64: 742-3 (2009)
PM ID: 19717708
154: Lee HR, Kim MH, Lee JS, Liang C, Jung JU
Viral interferon regulatory factors.
J Interferon Cytokine Res 29: 621-7 (2009)
PM ID: 19715458
155: Gundimeda U, Schiffman JE, Gottlieb SN, Roth BI, Gopalakrishna R
Negation of the cancer-preventive actions of selenium by over-expression of protein kinase Cepsilon and selenoprotein thioredoxin reductase.
Carcinogenesis 30: 1553-61 (2009)
PM ID: 19578042
156: Jeong KW, Lee YH, Stallcup MR
Recruitment of the SWI/SNF chromatin remodeling complex to steroid hormone-regulated promoters by nuclear receptor coactivator flightless-I.
J Biol Chem 284: 29298-309 (2009)
PM ID: 19720835
157: Jeong S, Liang G, Sharma S, Lin JC, Choi SH, Han H, Yoo CB, Egger G, Yang AS, Jones PA
Selective anchoring of DNA methyltransferases 3A and 3B to nucleosomes containing methylated DNA.
Mol Cell Biol 29: 5366-76 (2009)
PM ID: 19620278 PMC2747980 [Available on 04/01/10]
158: Poynter JN, Haile RW, Siegmund KD, Campbell PT, Figueiredo JC, Limburg P, Young J, Le Marchand L, Potter JD, Cotterchio M, Casey G, Hopper JL, Jenkins MA, Thibodeau SN, Newcomb PA, Baron JA, Colon Cancer Family Registry
Associations between smoking, alcohol consumption, and colorectal cancer, overall and by tumor microsatellite instability status.
Cancer Epidemiol Biomarkers Prev 18: 2745-50 (2009)
PM ID: 19755657 PMC2759847 NIHMS140217
159: Huang X, Bringas P, Slavkin HC, Chai Y
Fate of HERS during tooth root development.
Dev Biol 334: 22-30 (2009)
PM ID: 19576204 PMC2744848 [Available on 10/01/10] NIHMS139234 [Available on 10/01/10]
160: Lin CM, Jiang TX, Baker RE, Maini PK, Widelitz RB, Chuong CM
Spots and stripes: pleomorphic patterning of stem cells via p-ERK-dependent cell chemotaxis shown by feather morphogenesis and mathematical simulation.
Dev Biol 334: 369-82 (2009)
PM ID: 19647731
161: Choi J, Heo K, An W
Cooperative action of TIP48 and TIP49 in H2A.Z exchange catalyzed by acetylation of nucleosomal H2A.
Nucleic Acids Res 37: 5993-6007 (2009)
PM ID: 19696079 PMC2764430
162: Tiozzo C, De Langhe S, Yu MC, Londhe VA, Carraro G, Li M, Li C, Xing Y, Anderson SA, Borok Z, Bellusci S, Minoo P
Deletion of Pten expands lung epithelial progenitor pools and confers resistance to airway injury.
Am J Respir Crit Care Med 180: 701-12 (2009)
PM ID: 19574443
163: E X, Hwang S, Oh S, Lee JS, Jeong JH, Gwack Y, Kowalik TF, Sun R, Jung JU, Liang C
Viral Bcl-2-mediated evasion of autophagy aids chronic infection of gammaherpesvirus 68.
PLoS Pathog 5: e1000609 (2009)
PM ID: 19816569 PMC2752191
164: Jones PA, Liang G
Rethinking how DNA methylation patterns are maintained.
Nat Rev Genet 10: 805-11 (2009)
PM ID: 19789556 PMC2848124 [Available on 11/01/10] NIHMS185221 [Available on 11/01/10]
165: Gaudet MM, Campan M, Figueroa JD, Yang XR, Lissowska J, Peplonska B, Brinton LA, Rimm DL, Laird PW, Garcia-Closas M, Sherman ME
DNA hypermethylation of ESR1 and PGR in breast cancer: pathologic and epidemiologic associations.
Cancer Epidemiol Biomarkers Prev 18: 3036-43 (2009)
PM ID: 19861523 PMC2783691 [Available on 11/01/10] NIHMS149883 [Available on 11/01/10]
166: Dieli-Conwright CM, Spektor TM, Rice JC, Sattler FR, Schroeder ET
Influence of hormone replacement therapy on eccentric exercise induced myogenic gene expression in postmenopausal women.
J Appl Physiol 107: 1381-8 (2009)
PM ID: 19696363 PMC2777804 [Available on 11/01/10]
167: Dieli-Conwright CM, Spektor TM, Rice JC, Todd Schroeder E
Oestradiol and SERM treatments influence oestrogen receptor coregulator gene expression in human skeletal muscle cells.
Acta Physiol (Oxf) 197: 187-96 (2009)
PM ID: 19432593
168: Felton VM, Borok Z, Willis BC
N-acetylcysteine inhibits alveolar epithelial-mesenchymal transition.
Am J Physiol Lung Cell Mol Physiol 297: L805-12 (2009)
PM ID: 19648289 PMC2777496 [Available on 11/01/10]
169: Lee JS, Li Q, Lee JY, Lee SH, Jeong JH, Lee HR, Chang H, Zhou FC, Gao SJ, Liang C, Jung JU
FLIP-mediated autophagy regulation in cell death control.
Nat Cell Biol 11: 1355-62 (2009)
PM ID: 19838173 PMC2802862 [Available on 11/01/10] NIHMS165792 [Available on 11/01/10]
170: Xu TX, Sotnikova TD, Liang C, Zhang J, Jung JU, Spealman RD, Gainetdinov RR, Yao WD
Hyperdopaminergic tone erodes prefrontal long-term potential via a D2 receptor-operated protein phosphatase gate.
J Neurosci 29: 14086-99 (2009)
PM ID: 19906957 PMC2818669 [Available on 05/11/10] NIHMS163955 [Available on 05/11/10]
171: Stiles BL
PI-3-K and AKT: Onto the mitochondria.
Adv Drug Deliv Rev 61: 1276-82 (2009)
PM ID: 19720099
172: Hu K, Lee C, Qiu D, Fotovati A, Davies A, Abu-Ali S, Wai D, Lawlor ER, Triche TJ, Pallen CJ, Dunn SE
Small interfering RNA library screen of human kinases and phosphatases identifies polo-like kinase 1 as a promising new target for the treatment of pediatric rhabdomyosarcomas.
Mol Cancer Ther 8: 3024-35 (2009)
PM ID: 19887553 PMC2783569 [Available on 11/03/10] NIHMS150149 [Available on 11/03/10]
173: Lee AS
The Par-4-GRP78 TRAIL, more twists and turns.
Cancer Biol Ther 8: 2103-5 (2009)
PM ID: 19823030
174: Byun HM, Siegmund KD, Pan F, Weisenberger DJ, Kanel G, Laird PW, Yang AS
Epigenetic profiling of somatic tissues from human autopsy specimens identifies tissue- and individual-specific DNA methylation patterns.
Hum Mol Genet 18: 4808-17 (2009)
PM ID: 19776032
175: Kazarian M, Calbo J, Proost N, Carpenter CL, Berns A, Laird-Offringa IA
Immune response in lung cancer mouse model mimics human anti-Hu reactivity.
J Neuroimmunol 217: 38-45 (2009)
PM ID: 19765830 PMC2788043 [Available on 12/10/10] NIHMS144833 [Available on 12/10/10]
176: Borok Z, Crandall ED
More life for a "terminal" cell.
Am J Physiol Lung Cell Mol Physiol 297: L1042-4 (2009)
PM ID: 19837848 PMC2793181 [Available on 12/01/10]
177: Wei Z, Yang Y, Zhang P, Andrianakos R, Hasegawa K, Lyu J, Chen X, Bai G, Liu C, Pera M, Lu W
Klf4 interacts directly with Oct4 and Sox2 to promote reprogramming.
Stem Cells 27: 2969-78 (2009)
PM ID: 19816951
178: Ricca TI, Liang G, Suenaga AP, Han SW, Jones PA, Jasiulionis MG
Tissue inhibitor of metalloproteinase 1 expression associated with gene demethylation confers anoikis resistance in early phases of melanocyte malignant transformation.
Transl Oncol 2: 329-40 (2009)
PM ID: 19956395 PMC2781071
179: Houshdaran S, Hawley S, Palmer C, Campan M, Olsen MN, Ventura AP, Knudsen BS, Drescher CW, Urban ND, Brown PO, Laird PW
DNA methylation profiles of ovarian epithelial carcinoma tumors and cell lines.
PLoS One 5: e9359 (2010)
PM ID: 20179752 PMC2825254
180: Mao C, Wang M, Luo B, Wey S, Dong D, Wesselschmidt R, Rawlings S, Lee AS
Targeted mutation of the mouse Grp94 gene disrupts development and perturbs endoplasmic reticulum stress signaling.
PLoS One 5: e10852 (2010)
PM ID: 20520781 PMC2877114
181: Kim M, Long TI, Arakawa K, Wang R, Yu MC, Laird PW
DNA methylation as a biomarker for cardiovascular disease risk.
PLoS One 5: e9692 (2010)
PM ID: 20300621 PMC2837739
182: Jiang X, Gwye Y, Russell D, Cao C, Douglas D, Hung L, Kovar H, Triche TJ, Lawlor ER
CD133 expression in chemo-resistant Ewing sarcoma cells.
BMC Cancer 10: 116 (2010)
PM ID: 20346143 PMC2851692
183: Qiu X, Hother C, Ralfkiær UM, Søgaard A, Lu Q, Workman CT, Liang G, Jones PA, Grønbaek K
Equitoxic doses of 5-azacytidine and 5-aza-2'deoxycytidine induce diverse immediate and overlapping heritable changes in the transcriptome.
PLoS One 5: (2010)
PM ID: 20927380 PMC2947512
184: Hong YJ, Marjoram P, Shibata D, Siegmund KD
Using DNA methylation patterns to infer tumor ancestry.
PLoS One 5: e12002 (2010)
PM ID: 20711251 PMC2918495
185: Baniwal SK, Khalid O, Gabet Y, Shah RR, Purcell DJ, Mav D, Kohn-Gabet AE, Shi Y, Coetzee GA, Frenkel B
Runx2 transcriptome of prostate cancer cells: insights into invasiveness and bone metastasis.
Mol Cancer 9: 258 (2010)
PM ID: 20863401 PMC2955618
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The Wnt signaling pathway in cellular proliferation and differentiation: A tale of two coactivators.
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Unique DNA methylation patterns distinguish noninvasive and invasive urothelial cancers and establish an epigenetic field defect in premalignant tissue.
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Vitamin C promotes widespread yet specific DNA demethylation of the epigenome in human embryonic stem cells.
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Jagged1 functions downstream of Twist1 in the specification of the coronal suture and the formation of a boundary between osteogenic and non-osteogenic cells.
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Targeting DNA methylation for epigenetic therapy.
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Hypertension, diuretics and antihypertensives in relation to bladder cancer.
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Green tea polyphenols potentiate the action of nerve growth factor to induce neuritogenesis: possible role of reactive oxygen species.
J Neurosci Res 88: 3644-55 (2010)
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Polymorphisms in base excision repair genes as colorectal cancer risk factors and modifiers of the effect of diets high in red meat.
Cancer Epidemiol Biomarkers Prev 19: 3167-73 (2010)
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Liver-specific deletion of prohibitin 1 results in spontaneous liver injury, fibrosis, and hepatocellular carcinoma in mice.
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Expansion of hepatic tumor progenitor cells in Pten-null mice requires liver injury and is reversed by loss of AKT2.
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TSLP polymorphisms are associated with asthma in a sex-specific fashion.
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Measurement and modification of the expression level of the chaperone protein and signaling regulator GRP78/BiP in mammalian cells.
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TPL2/COT/MAP3K8 (TPL2) activation promotes androgen depletion-independent (ADI) prostate cancer growth.
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Small-cell lung cancer-associated autoantibodies: potential applications to cancer diagnosis, early detection, and therapy.
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Human and great ape red blood cells differ in plasmalogen levels and composition.
Lipids Health Dis 10: 101 (2011)
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High DNA methylation pattern intratumoral diversity implies weak selection in many human colorectal cancers.
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The endoplasmic reticulum chaperone protein GRP94 is required for maintaining hematopoietic stem cell interactions with the adult bone marrow niche.
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A let-7 microRNA-binding site polymorphism in 3'-untranslated region of KRAS gene predicts response in wild-type KRAS patients with metastatic colorectal cancer treated with cetuximab monotherapy.
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Alcohol induces RNA polymerase III-dependent transcription through c-Jun by co-regulating TATA-binding protein (TBP) and Brf1 expression.
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The PREMM(1,2,6) model predicts risk of MLH1, MSH2, and MSH6 germline mutations based on cancer history.
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Role of nucleosomes in mitotic bookmarking.
Cell Cycle 10: 370-1 (2011)
PM ID: 21270523
278: Oh S, Pirooz SD, Ni D, Zhao Z, Liang C
Anti-autophagic Bcl-2: Not just an innocent bystander.
Autophagy 7: 231-2 (2011)
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279: Ouyang YB, Xu LJ, Emery JF, Lee AS, Giffard RG
Overexpressing GRP78 influences Ca2+ handling and function of mitochondria in astrocytes after ischemia-like stress.
Mitochondrion 11: 279-86 (2011)
PM ID: 21047562 PMC3037025 NIHMS254326
280: Oh S, Xiaofei E, Ni D, Pirooz SD, Lee JY, Lee D, Zhao Z, Lee S, Lee H, Ku B, Kowalik T, Martin SE, Oh BH, Jung JU, Liang C
Downregulation of autophagy by Bcl-2 promotes MCF7 breast cancer cell growth independent of its inhibition of apoptosis.
Cell Death Differ 18: 452-64 (2011)
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281: Ni M, Zhang Y, Lee AS
Beyond the endoplasmic reticulum: atypical GRP78 in cell viability, signalling and therapeutic targeting.
Biochem J 434: 181-8 (2011)
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282: Pfaffenbach KT, Lee AS
The critical role of GRP78 in physiologic and pathologic stress.
Curr Opin Cell Biol 23: 150-6 (2011)
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283: Ku B, Liang C, Jung JU, Oh BH
Evidence that inhibition of BAX activation by BCL-2 involves its tight and preferential interaction with the BH3 domain of BAX.
Cell Res 21: 627-41 (2011)
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284: Protiva P, Mason JB, Liu Z, Hopkins ME, Nelson C, Marshall JR, Lambrecht RW, Pendyala S, Kopelovich L, Kim M, Kleinstein SH, Laird PW, Lipkin M, Holt PR
Altered folate availability modifies the molecular environment of the human colorectum: implications for colorectal carcinogenesis.
Cancer Prev Res (Phila) 4: 530-43 (2011)
PM ID: 21321062 PMC3742550 NIHMS264530
285: Hughes MW, Wu P, Jiang TX, Lin SJ, Dong CY, Li A, Hsieh FJ, Widelitz RB, Chuong CM
In search of the Golden Fleece: unraveling principles of morphogenesis by studying the integrative biology of skin appendages.
Integr Biol (Camb) 3: 388-407 (2011)
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286: Molognoni F, Cruz AT, Meliso FM, Morais AS, Souza CF, Xander P, Bischof JM, Costa FF, Soares MB, Liang G, Jones PA, Jasiulionis MG
Epigenetic reprogramming as a key contributor to melanocyte malignant transformation.
Epigenetics 6: 450-64 (2011)
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287: Dong D, Stapleton C, Luo B, Xiong S, Ye W, Zhang Y, Jhaveri N, Zhu G, Ye R, Liu Z, Bruhn KW, Craft N, Groshen S, Hofman FM, Lee AS
A critical role for GRP78/BiP in the tumor microenvironment for neovascularization during tumor growth and metastasis.
Cancer Res 71: 2848-57 (2011)
PM ID: 21467168 PMC3078191 NIHMS276417
288: Cao AR, Rabinovich R, Xu M, Xu X, Jin VX, Farnham PJ
Genome-wide analysis of transcription factor E2F1 mutant proteins reveals that N- and C-terminal protein interaction domains do not participate in targeting E2F1 to the human genome.
J Biol Chem 286: 11985-96 (2011)
PM ID: 21310950 PMC3069401
289: Zhao H, Li S, Han D, Kaartinen V, Chai Y
Alk5-mediated transforming growth factor β signaling acts upstream of fibroblast growth factor 10 to regulate the proliferation and maintenance of dental epithelial stem cells.
Mol Cell Biol 31: 2079-89 (2011)
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290: Ou CY, LaBonte MJ, Manegold PC, So AY, Ianculescu I, Gerke DS, Yamamoto KR, Ladner RD, Kahn M, Kim JH, Stallcup MR
A coactivator role of CARM1 in the dysregulation of β-catenin activity in colorectal cancer cell growth and gene expression.
Mol Cancer Res 9: 660-70 (2011)
PM ID: 21478268 PMC3096696 NIHMS284281
291: Lee YH, Stallcup MR
Roles of protein arginine methylation in DNA damage signaling pathways is CARM1 a life-or-death decision point?
Cell Cycle 10: 1343-4 (2011)
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292: Hung Y, Huang X, Chai Y
Molecular regulatory mechanism of root development.
J Calif Dent Assoc 39: 321-4 (2011)
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293: Li J, Huang X, Xu X, Mayo J, Bringas P, Jiang R, Wang S, Chai Y
SMAD4-mediated WNT signaling controls the fate of cranial neural crest cells during tooth morphogenesis.
Development 138: 1977-89 (2011)
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294: Zaro BW, Yang YY, Hang HC, Pratt MR
Chemical reporters for fluorescent detection and identification of O-GlcNAc-modified proteins reveal glycosylation of the ubiquitin ligase NEDD4-1.
Proc Natl Acad Sci U S A 108: 8146-51 (2011)
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295: Trojer P, Cao AR, Gao Z, Li Y, Zhang J, Xu X, Li G, Losson R, Erdjument-Bromage H, Tempst P, Farnham PJ, Reinberg D
L3MBTL2 protein acts in concert with PcG protein-mediated monoubiquitination of H2A to establish a repressive chromatin structure.
Mol Cell 42: 438-50 (2011)
PM ID: 21596310 PMC3142354 NIHMS300350
296: Iyengar S, Ivanov AV, Jin VX, Rauscher FJ, Farnham PJ
Functional analysis of KAP1 genomic recruitment.
Mol Cell Biol 31: 1833-47 (2011)
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297: Oghamian S, Sodir NM, Bashir MU, Shen H, Cullins AE, Carroll CA, Kundu P, Shibata D, Laird PW
Reduction of pancreatic acinar cell tumor multiplicity in Dnmt1 hypomorphic mice.
Carcinogenesis 32: 829-35 (2011)
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298: Kim S, Wang M, Lee AS, Thompson RF
Impaired eyeblink conditioning in 78 kDa-glucose regulated protein (GRP78)/immunoglobulin binding protein (BiP) conditional knockout mice.
Behav Neurosci 125: 404-11 (2011)
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299: Cancer Genome Atlas Research Network
Integrated genomic analyses of ovarian carcinoma.
Nature 474: 609-15 (2011)
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300: Freedman ML, Monteiro AN, Gayther SA, Coetzee GA, Risch A, Plass C, Casey G, De Biasi M, Carlson C, Duggan D, James M, Liu P, Tichelaar JW, Vikis HG, You M, Mills IG
Principles for the post-GWAS functional characterization of cancer risk loci.
Nat Genet 43: 513-8 (2011)
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301: Weiss DJ, Bertoncello I, Borok Z, Kim C, Panoskaltsis-Mortari A, Reynolds S, Rojas M, Stripp B, Warburton D, Prockop DJ
Stem cells and cell therapies in lung biology and lung diseases.
Proc Am Thorac Soc 8: 223-72 (2011)
PM ID: 21653527 PMC3132784
302: Jiang TX, Tuan TL, Wu P, Widelitz RB, Chuong CM
From buds to follicles: matrix metalloproteinases in developmental tissue remodeling during feather morphogenesis.
Differentiation 81: 307-14 (2011)
PM ID: 21497985 PMC3114260 NIHMS286448
303: Siegmund KD
Statistical approaches for the analysis of DNA methylation microarray data.
Hum Genet 129: 585-95 (2011)
PM ID: 21519831 PMC3166559 NIHMS317655
304: Borok Z, Whitsett JA, Bitterman PB, Thannickal VJ, Kotton DN, Reynolds SD, Krasnow MA, Bianchi DW, Morrisey EE, Hogan BL, Kurie JM, Walker DC, Radisky DC, Nishimura SL, Violette SM, Noble PW, Shapiro SD, Blaisdell CJ, Chapman HA, other participants
Cell plasticity in lung injury and repair: report from an NHLBI workshop, April 19-20, 2010.
Proc Am Thorac Soc 8: 215-22 (2011)
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305: Lyu J, Jho EH, Lu W
Smek promotes histone deacetylation to suppress transcription of Wnt target gene brachyury in pluripotent embryonic stem cells.
Cell Res 21: 911-21 (2011)
PM ID: 21423269 PMC3203701
306: Zhou H, Zhang Y, Fu Y, Chan L, Lee AS
Novel mechanism of anti-apoptotic function of 78-kDa glucose-regulated protein (GRP78): endocrine resistance factor in breast cancer, through release of B-cell lymphoma 2 (BCL-2) from BCL-2-interacting killer (BIK).
J Biol Chem 286: 25687-96 (2011)
PM ID: 21622563 PMC3138298
307: Breton CV, Byun HM, Wang X, Salam MT, Siegmund K, Gilliland FD
DNA methylation in the arginase-nitric oxide synthase pathway is associated with exhaled nitric oxide in children with asthma.
Am J Respir Crit Care Med 184: 191-7 (2011)
PM ID: 21512169 PMC3172885
308: Iyengar S, Farnham PJ
KAP1 protein: an enigmatic master regulator of the genome.
J Biol Chem 286: 26267-76 (2011)
PM ID: 21652716 PMC3143589
309: Ji C, Kaplowitz N, Lau MY, Kao E, Petrovic LM, Lee AS
Liver-specific loss of glucose-regulated protein 78 perturbs the unfolded protein response and exacerbates a spectrum of liver diseases in mice.
Hepatology 54: 229-39 (2011)
PM ID: 21503947 PMC3125405 NIHMS288241
310: Qiu X, Friedman JM, Liang G
Creating a flexible multiple microRNA expression vector by linking precursor microRNAs.
Biochem Biophys Res Commun 411: 276-80 (2011)
PM ID: 21726537 PMC3148277 NIHMS307892
311: Park E, Gang EJ, Hsieh YT, Schaefer P, Chae S, Klemm L, Huantes S, Loh M, Conway EM, Kang ES, Hoe Koo H, Hofmann WK, Heisterkamp N, Pelus L, Keerthivasan G, Crispino J, Kahn M, Müschen M, Kim YM
Targeting survivin overcomes drug resistance in acute lymphoblastic leukemia.
Blood 118: 2191-9 (2011)
PM ID: 21715311 PMC3162353
312: Davis-Dao CA, Siegmund KD, Vandenberg DJ, Skinner EC, Coetzee GA, Thomas DC, Pike MC, Cortessis VK
Heterogenous effect of androgen receptor CAG tract length on testicular germ cell tumor risk: shorter repeats associated with seminoma but not other histologic types.
Carcinogenesis 32: 1238-43 (2011)
PM ID: 21642359 PMC3202310
313: Buchanan G, Need EF, Barrett JM, Bianco-Miotto T, Thompson VC, Butler LM, Marshall VR, Tilley WD, Coetzee GA
Corepressor effect on androgen receptor activity varies with the length of the CAG encoded polyglutamine repeat and is dependent on receptor/corepressor ratio in prostate cancer cells.
Mol Cell Endocrinol 342: 20-31 (2011)
PM ID: 21664238 PMC3314496 NIHMS308521
314: Ye R, Ni M, Wang M, Luo S, Zhu G, Chow RH, Lee AS
Inositol 1,4,5-trisphosphate receptor 1 mutation perturbs glucose homeostasis and enhances susceptibility to diet-induced diabetes.
J Endocrinol 210: 209-17 (2011)
PM ID: 21565852 PMC3137733 NIHMS298818
315: You JS, Kelly TK, De Carvalho DD, Taberlay PC, Liang G, Jones PA
OCT4 establishes and maintains nucleosome-depleted regions that provide additional layers of epigenetic regulation of its target genes.
Proc Natl Acad Sci U S A 108: 14497-502 (2011)
PM ID: 21844352 PMC3167525
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Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.
Nature 476: 214-9 (2011)
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317: Hinch AG, Tandon A, Patterson N, Song Y, Rohland N, Palmer CD, Chen GK, Wang K, Buxbaum SG, Akylbekova EL, Aldrich MC, Ambrosone CB, Amos C, Bandera EV, Berndt SI, Bernstein L, Blot WJ, Bock CH, Boerwinkle E, Cai Q, Caporaso N, Casey G, Cupples LA, Deming SL, Diver WR, Divers J, Fornage M, Gillanders EM, Glessner J, Harris CC, Hu JJ, Ingles SA, Isaacs W, John EM, Kao WH, Keating B, Kittles RA, Kolonel LN, Larkin E, Le Marchand L, McNeill LH, Millikan RC, Murphy A, Musani S, Neslund-Dudas C, Nyante S, Papanicolaou GJ, Press MF, Psaty BM, Reiner AP, Rich SS, Rodriguez-Gil JL, Rotter JI, Rybicki BA, Schwartz AG, Signorello LB, Spitz M, Strom SS, Thun MJ, Tucker MA, Wang Z, Wiencke JK, Witte JS, Wrensch M, Wu X, Yamamura Y, Zanetti KA, Zheng W, Ziegler RG, Zhu X, Redline S, Hirschhorn JN, Henderson BE, Taylor HA, Price AL, Hakonarson H, Chanock SJ, Haiman CA, Wilson JG, Reich D, Myers SR
The landscape of recombination in African Americans.
Nature 476: 170-5 (2011)
PM ID: 21775986 PMC3154982 NIHMS313104
318: Lee G, Liang C, Park G, Jang C, Jung JU, Chung J
UVRAG is required for organ rotation by regulating Notch endocytosis in Drosophila.
Dev Biol 356: 588-97 (2011)
PM ID: 21729695
319: Zhong Q, Zhou B, Ann DK, Minoo P, Liu Y, Banfalvi A, Krishnaveni MS, Dubourd M, Demaio L, Willis BC, Kim KJ, Dubois RM, Crandall ED, Beers MF, Borok Z
Role of endoplasmic reticulum stress in epithelial-mesenchymal transition of alveolar epithelial cells: effects of misfolded surfactant protein.
Am J Respir Cell Mol Biol 45: 498-509 (2011)
PM ID: 21169555 PMC3175581
320: Ji Yu E, Kim SH, Heo K, Ou CY, Stallcup MR, Kim JH
Reciprocal roles of DBC1 and SIRT1 in regulating estrogen receptor α activity and co-activator synergy.
Nucleic Acids Res 39: 6932-43 (2011)
PM ID: 21596782 PMC3167635
321: Zaro BW, Bateman LA, Pratt MR
Robust in-gel fluorescence detection of mucin-type O-linked glycosylation.
Bioorg Med Chem Lett 21: 5062-6 (2011)
PM ID: 21531554
322: Wang J, Siegmund K, Tseng CC, Lee AS, Wu AH
Soy food supplementation, dietary fat reduction and peripheral blood gene expression in postmenopausal women--a randomized, controlled trial.
Mol Nutr Food Res 55 Suppl 2: S264-77 (2011)
PM ID: 21823222
323: Fazlollahi F, Angelow S, Yacobi NR, Marchelletta R, Yu AS, Hamm-Alvarez SF, Borok Z, Kim KJ, Crandall ED
Polystyrene nanoparticle trafficking across MDCK-II.
Nanomedicine 7: 588-94 (2011)
PM ID: 21310266 PMC3130091 NIHMS273797
324: Kim H, Heo K, Choi J, Kim K, An W
Histone variant H3.3 stimulates HSP70 transcription through cooperation with HP1γ.
Nucleic Acids Res 39: 8329-41 (2011)
PM ID: 21742762 PMC3201866
325: Baylin SB, Jones PA
A decade of exploring the cancer epigenome - biological and translational implications.
Nat Rev Cancer 11: 726-34 (2011)
PM ID: 21941284 PMC3307543 NIHMS358721
326: Kahn M
Symmetric division versus asymmetric division: a tale of two coactivators.
Future Med Chem 3: 1745-63 (2011)
PM ID: 22004083
327: Winder T, Bohanes P, Zhang W, Yang D, Power DG, Ning Y, Gerger A, Wilson PM, Tang LH, Shah M, Lee AS, Lenz HJ
GRP78 promoter polymorphism rs391957 as potential predictor for clinical outcome in gastric and colorectal cancer patients.
Ann Oncol 22: 2431-9 (2011)
PM ID: 21382870 PMC3200220
328: Miki T, Yasuda SY, Kahn M
Wnt/β-catenin signaling in embryonic stem cell self-renewal and somatic cell reprogramming.
Stem Cell Rev 7: 836-46 (2011)
PM ID: 21603945
329: Han H, Cortez CC, Yang X, Nichols PW, Jones PA, Liang G
DNA methylation directly silences genes with non-CpG island promoters and establishes a nucleosome occupied promoter.
Hum Mol Genet 20: 4299-310 (2011)
PM ID: 21835883 PMC3196883
330: Gerger A, Zhang W, Yang D, Bohanes P, Ning Y, Winder T, LaBonte MJ, Wilson PM, Benhaim L, Paez D, El-Khoueiry R, El-Khoueiry A, Kahn M, Lenz HJ
Common cancer stem cell gene variants predict colon cancer recurrence.
Clin Cancer Res 17: 6934-43 (2011)
PM ID: 21918173
331: Cheng CF, Sahu D, Tsen F, Zhao Z, Fan J, Kim R, Wang X, O'Brien K, Li Y, Kuang Y, Chen M, Woodley DT, Li W
A fragment of secreted Hsp90α carries properties that enable it to accelerate effectively both acute and diabetic wound healing in mice.
J Clin Invest 121: 4348-61 (2011)
PM ID: 22019588 PMC3204835
332: Choi J, Kim H, Kim K, Lee B, Lu W, An W
Selective requirement of H2B N-Terminal tail for p14ARF-induced chromatin silencing.
Nucleic Acids Res 39: 9167-80 (2011)
PM ID: 21846774 PMC3241654
333: Purcell DJ, Jeong KW, Bittencourt D, Gerke DS, Stallcup MR
A distinct mechanism for coactivator versus corepressor function by histone methyltransferase G9a in transcriptional regulation.
J Biol Chem 286: 41963-71 (2011)
PM ID: 21984853 PMC3234941
334: Andreu-Vieyra C, Lai J, Berman BP, Frenkel B, Jia L, Jones PA, Coetzee GA
Dynamic nucleosome-depleted regions at androgen receptor enhancers in the absence of ligand in prostate cancer cells.
Mol Cell Biol 31: 4648-62 (2011)
PM ID: 21969603 PMC3232925
335: Tian Y, Sir D, Kuo CF, Ann DK, Ou JH
Autophagy required for hepatitis B virus replication in transgenic mice.
J Virol 85: 13453-6 (2011)
PM ID: 21957292 PMC3233133
336: Razzak AA, Oxentenko AS, Vierkant RA, Tillmans LS, Wang AH, Weisenberger DJ, Laird PW, Lynch CF, Anderson KE, French AJ, Haile RW, Harnack LJ, Slager SL, Smyrk TC, Thibodeau SN, Cerhan JR, Limburg PJ
Alcohol intake and colorectal cancer risk by molecularly defined subtypes in a prospective study of older women.
Cancer Prev Res (Phila) 4: 2035-43 (2011)
PM ID: 21900595 PMC3584678 NIHMS441368
337: Cortessis VK, Siegmund K, Houshdaran S, Laird PW, Sokol RZ
Repeated assessment by high-throughput assay demonstrates that sperm DNA methylation levels are highly reproducible.
Fertil Steril 96: 1325-30 (2011)
PM ID: 22035967 PMC3448450 NIHMS334785
338: Zeng N, Li Y, He L, Xu X, Galicia V, Deng C, Stiles BL
Adaptive basal phosphorylation of eIF2α is responsible for resistance to cellular stress-induced cell death in Pten-null hepatocytes.
Mol Cancer Res 9: 1708-17 (2011)
PM ID: 22009178
339: Jeong KW, Kim K, Situ AJ, Ulmer TS, An W, Stallcup MR
Recognition of enhancer element-specific histone methylation by TIP60 in transcriptional activation.
Nat Struct Mol Biol 18: 1358-65 (2011)
PM ID: 22081016 PMC3230772 NIHMS321138
340: Taberlay PC, Kelly TK, Liu CC, You JS, De Carvalho DD, Miranda TB, Zhou XJ, Liang G, Jones PA
Polycomb-repressed genes have permissive enhancers that initiate reprogramming.
Cell 147: 1283-94 (2011)
PM ID: 22153073 PMC3240866 NIHMS338207
341: Noushmehr H, Coetzee GA
Identification and functional annotation of GWAS risk SNPs.
Cell Cycle 10: 3995-6 (2011)
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Screening ethnically diverse human embryonic stem cells identifies a chromosome 20 minimal amplicon conferring growth advantage.
Nat Biotechnol 29: 1132-44 (2011)
PM ID: 22119741 PMC3454460 NIHMS399467
343: Sharma S, Gerke DS, Han HF, Jeong S, Stallcup MR, Jones PA, Liang G
Lysine methyltransferase G9a is not required for DNMT3A/3B anchoring to methylated nucleosomes and maintenance of DNA methylation in somatic cells.
Epigenetics Chromatin 5: 3 (2012)
PM ID: 22284370 PMC3292817
344: Kennedy BA, Lan X, Huang TH, Farnham PJ, Jin VX
Using ChIPMotifs for de novo motif discovery of OCT4 and ZNF263 based on ChIP-based high-throughput experiments.
Methods Mol Biol 802: 323-34 (2012)
PM ID: 22130890
345: Yang X, Noushmehr H, Han H, Andreu-Vieyra C, Liang G, Jones PA
Gene reactivation by 5-aza-2'-deoxycytidine-induced demethylation requires SRCAP-mediated H2A.Z insertion to establish nucleosome depleted regions.
PLoS Genet 8: e1002604 (2012)
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346: Yusuf D, Butland SL, Swanson MI, Bolotin E, Ticoll A, Cheung WA, Zhang XY, Dickman CT, Fulton DL, Lim JS, Schnabl JM, Ramos OH, Vasseur-Cognet M, de Leeuw CN, Simpson EM, Ryffel GU, Lam EW, Kist R, Wilson MS, Marco-Ferreres R, Brosens JJ, Beccari LL, Bovolenta P, Benayoun BA, Monteiro LJ, Schwenen HD, Grontved L, Wederell E, Mandrup S, Veitia RA, Chakravarthy H, Hoodless PA, Mancarelli M, Torbett BE, Banham AH, Reddy SP, Cullum RL, Liedtke M, Tschan MP, Vaz M, Rizzino A, Zannini M, Frietze S, Farnham PJ, Eijkelenboom A, Brown PJ, Laperriere D, Leprince D, de Cristofaro T, Prince KL, Putker M, Del Peso L, Camenisch G, Wenger RH, Mikula M, Rozendaal M, Mader S, Ostrowski J, Rhodes SJ, Van Rechem C, Boulay G, Olechnowicz SW, Breslin MB, Lan MS, Nanan KK, Wegner M, Hou J, Mullen RD, Colvin SC, Noy PJ, Webb CF, Witek ME, Ferrell S, Daniel JM, Park J, Waldman SA, Peet DJ, Taggart M, Jayaraman PS, Karrich JJ, Blom B, Vesuna F, O'Geen H, Sun Y, Gronostajski RM, Woodcroft MW, Hough MR, Chen E, Europe-Finner N, Karolczak-Bayatti M, Bailey J, Hankinson O, Raman V, Lebrun DP, Biswal S, Harvey CJ, Debruyne JP, Hogenesch JB, Hevner RF, Heligon C, Luo XM, Blank MC, Millen KJ, Sharlin DS, Forrest D, Dahlman-Wright K, Zhao C, Mishima Y, Sinha S, Chakrabarti R, Portales-Casamar E, Sladek FM, Bradley PH, Wasserman WW
The transcription factor encyclopedia.
Genome Biol 13: R24 (2012)
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347: Brusslan JA, Rus Alvarez-Canterbury AM, Nair NU, Rice JC, Hitchler MJ, Pellegrini M
Genome-wide evaluation of histone methylation changes associated with leaf senescence in Arabidopsis.
PLoS One 7: e33151 (2012)
PM ID: 22427974 PMC3299739
348: Zhou B, Buckley ST, Patel V, Liu Y, Luo J, Krishnaveni MS, Ivan M, Demaio L, Kim KJ, Ehrhardt C, Crandall ED, Borok Z
Troglitazone attenuates TGF-β1-induced EMT in alveolar epithelial cells via a PPARγ-independent mechanism.
PLoS One 7: e38827 (2012)
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349: Wey S, Luo B, Lee AS
Acute inducible ablation of GRP78 reveals its role in hematopoietic stem cell survival, lymphogenesis and regulation of stress signaling.
PLoS One 7: e39047 (2012)
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350: Han H, Wolff EM, Liang G
Epigenetic alterations in bladder cancer and their potential clinical implications.
Adv Urol 2012: 546917 (2012)
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351: Ng CS, Wu P, Foley J, Foley A, McDonald ML, Juan WT, Huang CJ, Lai YT, Lo WS, Chen CF, Leal SM, Zhang H, Widelitz RB, Patel PI, Li WH, Chuong CM
The chicken frizzle feather is due to an α-keratin (KRT75) mutation that causes a defective rachis.
PLoS Genet 8: e1002748 (2012)
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352: Frietze S, Wang R, Yao L, Tak YG, Ye Z, Gaddis M, Witt H, Farnham PJ, Jin VX
Cell type-specific binding patterns reveal that TCF7L2 can be tethered to the genome by association with GATA3.
Genome Biol 13: R52 (2012)
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353: Razzak AA, Oxentenko AS, Vierkant RA, Tillmans LS, Wang AH, Weisenberger DJ, Laird PW, Lynch CF, Anderson KE, French AJ, Haile RW, Harnack LJ, Potter JD, Slager SL, Smyrk TC, Thibodeau SN, Cerhan JR, Limburg PJ
Associations between intake of folate and related micronutrients with molecularly defined colorectal cancer risks in the Iowa Women's Health Study.
Nutr Cancer 64: 899-910 (2012)
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354: Lange CP, Campan M, Hinoue T, Schmitz RF, van der Meulen-de Jong AE, Slingerland H, Kok PJ, van Dijk CM, Weisenberger DJ, Shen H, Tollenaar RA, Laird PW
Genome-scale discovery of DNA-methylation biomarkers for blood-based detection of colorectal cancer.
PLoS One 7: e50266 (2012)
PM ID: 23209692 PMC3508917
355: Wey S, Luo B, Tseng CC, Ni M, Zhou H, Fu Y, Bhojwani D, Carroll WL, Lee AS
Inducible knockout of GRP78/BiP in the hematopoietic system suppresses Pten-null leukemogenesis and AKT oncogenic signaling.
Blood 119: 817-25 (2012)
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356: Treppendahl MB, Qiu X, Søgaard A, Yang X, Nandrup-Bus C, Hother C, Andersen MK, Kjeldsen L, Möllgaard L, Hellström-Lindberg E, Jendholm J, Porse BT, Jones PA, Liang G, Grønbaek K
Allelic methylation levels of the noncoding VTRNA2-1 located on chromosome 5q31.1 predict outcome in AML.
Blood 119: 206-16 (2012)
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357: Coetzee GA
The usefulness of prostate cancer genome-wide association studies.
J Urol 187: 9-10 (2012)
PM ID: 22088348
358: Berman BP, Weisenberger DJ, Aman JF, Hinoue T, Ramjan Z, Liu Y, Noushmehr H, Lange CP, van Dijk CM, Tollenaar RA, Van Den Berg D, Laird PW
Regions of focal DNA hypermethylation and long-range hypomethylation in colorectal cancer coincide with nuclear lamina-associated domains.
Nat Genet 44: 40-6 (2012)
PM ID: 22120008
359: Iwata J, Tung L, Urata M, Hacia JG, Pelikan R, Suzuki A, Ramenzoni L, Chaudhry O, Parada C, Sanchez-Lara PA, Chai Y
Fibroblast growth factor 9 (FGF9)-pituitary homeobox 2 (PITX2) pathway mediates transforming growth factor β (TGFβ) signaling to regulate cell proliferation in palatal mesenchyme during mouse palatogenesis.
J Biol Chem 287: 2353-63 (2012)
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360: Kang YA, Sanalkumar R, O'Geen H, Linnemann AK, Chang CJ, Bouhassira EE, Farnham PJ, Keles S, Bresnick EH
Autophagy driven by a master regulator of hematopoiesis.
Mol Cell Biol 32: 226-39 (2012)
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361: Hinoue T, Weisenberger DJ, Lange CP, Shen H, Byun HM, Van Den Berg D, Malik S, Pan F, Noushmehr H, van Dijk CM, Tollenaar RA, Laird PW
Genome-scale analysis of aberrant DNA methylation in colorectal cancer.
Genome Res 22: 271-82 (2012)
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362: Jenkins G, Blanchard A, Borok Z, Bradding P, Ehrhardt C, Fisher A, Hirani N, Johnson S, Königshoff M, Maher TM, Millar A, Parfrey H, Scotton C, Tetley T, Thickett D, Wolters P, ECIPF workshop
In search of the fibrotic epithelial cell: opportunities for a collaborative network.
Thorax 67: 179-82 (2012)
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363: Ianculescu I, Wu DY, Siegmund KD, Stallcup MR
Selective roles for cAMP response element-binding protein binding protein and p300 protein as coregulators for androgen-regulated gene expression in advanced prostate cancer cells.
J Biol Chem 287: 4000-13 (2012)
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364: Levine AJ, Win AK, Buchanan DD, Jenkins MA, Baron JA, Young JP, Long TI, Weisenberger DJ, Laird PW, McCall RL, Duggan DJ, Haile RW
Cancer risks for the relatives of colorectal cancer cases with a methylated MLH1 promoter region: data from the Colorectal Cancer Family Registry.
Cancer Prev Res (Phila) 5: 328-35 (2012)
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365: Sahu D, Zhao Z, Tsen F, Cheng CF, Park R, Situ AJ, Dai J, Eginli A, Shams S, Chen M, Ulmer TS, Conti P, Woodley DT, Li W
A potentially common peptide target in secreted heat shock protein-90α for hypoxia-inducible factor-1α-positive tumors.
Mol Biol Cell 23: 602-13 (2012)
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366: Kim K, Heo K, Choi J, Jackson S, Kim H, Xiong Y, An W
Vpr-binding protein antagonizes p53-mediated transcription via direct interaction with H3 tail.
Mol Cell Biol 32: 783-96 (2012)
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367: Kim H, Kim K, Choi J, Heo K, Baek HJ, Roeder RG, An W
p53 requires an intact C-terminal domain for DNA binding and transactivation.
J Mol Biol 415: 843-54 (2012)
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368: Choi I, Lee S, Kyoung Chung H, Suk Lee Y, Eui Kim K, Choi D, Park EK, Yang D, Ecoiffier T, Monahan J, Chen W, Aguilar B, Lee HN, Yoo J, Koh CJ, Chen L, Wong AK, Hong YK
9-cis retinoic acid promotes lymphangiogenesis and enhances lymphatic vessel regeneration: therapeutic implications of 9-cis retinoic acid for secondary lymphedema.
Circulation 125: 872-82 (2012)
PM ID: 22275501 PMC3327127 NIHMS357408
369: Liang C
Viral FLIPping autophagy for longevity.
Cell Host Microbe 11: 101-3 (2012)
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370: Li W, Sahu D, Tsen F
Secreted heat shock protein-90 (Hsp90) in wound healing and cancer.
Biochim Biophys Acta 1823: 730-41 (2012)
PM ID: 21982864 PMC3266443 NIHMS328588
371: Demaio L, Buckley ST, Krishnaveni MS, Flodby P, Dubourd M, Banfalvi A, Xing Y, Ehrhardt C, Minoo P, Zhou B, Crandall ED, Borok Z
Ligand-independent transforming growth factor-β type I receptor signalling mediates type I collagen-induced epithelial-mesenchymal transition.
J Pathol 226: 633-44 (2012)
PM ID: 21984393
372: Davis-Dao C, Koh CJ, Hardy BE, Chang A, Kim SS, De Filippo R, Hwang A, Pike MC, Carroll JD, Coetzee GA, VanDenBerg D, Siegmund K, Cortessis VK
Shorter androgen receptor CAG repeat lengths associated with cryptorchidism risk among Hispanic white boys.
J Clin Endocrinol Metab 97: E393-9 (2012)
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373: Zhou B, Liu Y, Kahn M, Ann DK, Han A, Wang H, Nguyen C, Flodby P, Zhong Q, Krishnaveni MS, Liebler JM, Minoo P, Crandall ED, Borok Z
Interactions between β-catenin and transforming growth factor-β signaling pathways mediate epithelial-mesenchymal transition and are dependent on the transcriptional co-activator cAMP-response element-binding protein (CREB)-binding protein (CBP).
J Biol Chem 287: 7026-38 (2012)
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374: Iwata J, Hacia JG, Suzuki A, Sanchez-Lara PA, Urata M, Chai Y
Modulation of noncanonical TGF-β signaling prevents cleft palate in Tgfbr2 mutant mice.
J Clin Invest 122: 873-85 (2012)
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375: Lin HH, Li X, Chen JL, Sun X, Cooper FN, Chen YR, Zhang W, Chung Y, Li A, Cheng CT, Yang L, Deng X, Liu X, Yen Y, Johnson DL, Shih HM, Yang A, Ann DK
Identification of an AAA ATPase VPS4B-dependent pathway that modulates epidermal growth factor receptor abundance and signaling during hypoxia.
Mol Cell Biol 32: 1124-38 (2012)
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376: Zada G, Bond AE, Wang YP, Giannotta SL, Deapen D
Incidence trends in the anatomic location of primary malignant brain tumors in the United States: 1992-2006.
World Neurosurg 77: 518-24 (2012)
PM ID: 22120376
377: Meier F, Abeywardana T, Dhall A, Marotta NP, Varkey J, Langen R, Chatterjee C, Pratt MR
Semisynthetic, site-specific ubiquitin modification of α-synuclein reveals differential effects on aggregation.
J Am Chem Soc 134: 5468-71 (2012)
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378: Yang CS, Lee JS, Rodgers M, Min CK, Lee JY, Kim HJ, Lee KH, Kim CJ, Oh B, Zandi E, Yue Z, Kramnik I, Liang C, Jung JU
Autophagy protein Rubicon mediates phagocytic NADPH oxidase activation in response to microbial infection or TLR stimulation.
Cell Host Microbe 11: 264-76 (2012)
PM ID: 22423966 PMC3616771 NIHMS361158
379: Wang J, Joshi AD, Corral R, Siegmund KD, Marchand LL, Martinez ME, Haile RW, Ahnen DJ, Sandler RS, Lance P, Stern MC
Carcinogen metabolism genes, red meat and poultry intake, and colorectal cancer risk.
Int J Cancer 130: 1898-907 (2012)
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380: Little GH, Noushmehr H, Baniwal SK, Berman BP, Coetzee GA, Frenkel B
Genome-wide Runx2 occupancy in prostate cancer cells suggests a role in regulating secretion.
Nucleic Acids Res 40: 3538-47 (2012)
PM ID: 22187159 PMC3333873
381: Yoo SA, You S, Yoon HJ, Kim DH, Kim HS, Lee K, Ahn JH, Hwang D, Lee AS, Kim KJ, Park YJ, Cho CS, Kim WU
A novel pathogenic role of the ER chaperone GRP78/BiP in rheumatoid arthritis.
J Exp Med 209: 871-86 (2012)
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382: Zhang H, Liu H, Borok Z, Davies KJ, Ursini F, Forman HJ
Cigarette smoke extract stimulates epithelial-mesenchymal transition through Src activation.
Free Radic Biol Med 52: 1437-42 (2012)
PM ID: 22342303 PMC3312989 NIHMS355137
383: Kerin T, Ramanathan A, Rivas K, Grepo N, Coetzee GA, Campbell DB
A noncoding RNA antisense to moesin at 5p14.1 in autism.
Sci Transl Med 4: 128ra40 (2012)
PM ID: 22491950
384: Shen H, Laird PW
In epigenetic therapy, less is more.
Cell Stem Cell 10: 353-4 (2012)
PM ID: 22482500
385: Chuong CM, Randall VA, Widelitz RB, Wu P, Jiang TX
Physiological regeneration of skin appendages and implications for regenerative medicine.
Physiology (Bethesda) 27: 61-72 (2012)
PM ID: 22505663 PMC3620028 NIHMS444851
386: Ting MC, Liao CP, Yan C, Jia L, Groshen S, Frenkel B, Roy-Burman P, Coetzee GA, Maxson R
An enhancer from the 8q24 prostate cancer risk region is sufficient to direct reporter gene expression to a subset of prostate stem-like epithelial cells in transgenic mice.
Dis Model Mech 5: 366-74 (2012)
PM ID: 22279083 PMC3339830
387: Han D, Zhao H, Parada C, Hacia JG, Bringas P, Chai Y
A TGFβ-Smad4-Fgf6 signaling cascade controls myogenic differentiation and myoblast fusion during tongue development.
Development 139: 1640-50 (2012)
PM ID: 22438570 PMC3317969
388: Xing Y, Li A, Borok Z, Li C, Minoo P
NOTCH1 is required for regeneration of Clara cells during repair of airway injury.
Stem Cells 30: 946-55 (2012)
PM ID: 22331706
389: Carter SL, Cibulskis K, Helman E, McKenna A, Shen H, Zack T, Laird PW, Onofrio RC, Winckler W, Weir BA, Beroukhim R, Pellman D, Levine DA, Lander ES, Meyerson M, Getz G
Absolute quantification of somatic DNA alterations in human cancer.
Nat Biotechnol 30: 413-21 (2012)
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390: Zhao Z, Oh S, Li D, Ni D, Pirooz SD, Lee JH, Yang S, Lee JY, Ghozalli I, Costanzo V, Stark JM, Liang C
A dual role for UVRAG in maintaining chromosomal stability independent of autophagy.
Dev Cell 22: 1001-16 (2012)
PM ID: 22542840 PMC3356442 NIHMS367824
391: De Carvalho DD, Sharma S, You JS, Su SF, Taberlay PC, Kelly TK, Yang X, Liang G, Jones PA
DNA methylation screening identifies driver epigenetic events of cancer cell survival.
Cancer Cell 21: 655-67 (2012)
PM ID: 22624715 PMC3395886 NIHMS374702
392: Won Jeong K, Chodankar R, Purcell DJ, Bittencourt D, Stallcup MR
Gene-specific patterns of coregulator requirements by estrogen receptor-α in breast cancer cells.
Mol Endocrinol 26: 955-66 (2012)
PM ID: 22543272 PMC3355545
393: Yen HY, Gabet Y, Liu Y, Martin A, Wu NL, Pike MC, Frenkel B, Maxson R, Dubeau L
Alterations in Brca1 expression in mouse ovarian granulosa cells have short-term and long-term consequences on estrogen-responsive organs.
Lab Invest 92: 802-11 (2012)
PM ID: 22488153
394: Lam G, Mehta V, Zada G
Spontaneous and medically induced cerebrospinal fluid leakage in the setting of pituitary adenomas: review of the literature.
Neurosurg Focus 32: E2 (2012)
PM ID: 22655691
395: Purcell DJ, Khalid O, Ou CY, Little GH, Frenkel B, Baniwal SK, Stallcup MR
Recruitment of coregulator G9a by Runx2 for selective enhancement or suppression of transcription.
J Cell Biochem 113: 2406-14 (2012)
PM ID: 22389001 PMC3350606 NIHMS363705
396: Jung CJ, Iyengar S, Blahnik KR, Jiang JX, Tahimic C, Torok NJ, De Vere White RW, Farnham PJ, Zern M
Human ESC self-renewal promoting microRNAs induce epithelial-mesenchymal transition in hepatocytes by controlling the PTEN and TGFβ tumor suppressor signaling pathways.
Mol Cancer Res 10: 979-91 (2012)
PM ID: 22622027
397: Jones PA
Functions of DNA methylation: islands, start sites, gene bodies and beyond.
Nat Rev Genet 13: 484-92 (2012)
PM ID: 22641018
398: Selamat SA, Chung BS, Girard L, Zhang W, Zhang Y, Campan M, Siegmund KD, Koss MN, Hagen JA, Lam WL, Lam S, Gazdar AF, Laird-Offringa IA
Genome-scale analysis of DNA methylation in lung adenocarcinoma and integration with mRNA expression.
Genome Res 22: 1197-211 (2012)
PM ID: 22613842 PMC3396362
399: You JS, Jones PA
Cancer genetics and epigenetics: two sides of the same coin?
Cancer Cell 22: 9-20 (2012)
PM ID: 22789535 PMC3396881 NIHMS388188
400: Liu Y, Siegmund KD, Laird PW, Berman BP
Bis-SNP: Combined DNA methylation and SNP calling for Bisulfite-seq data.
Genome Biol 13: R61 (2012)
PM ID: 22784381 PMC3491382
401: Chang JS, Ocvirk S, Berger E, Kisling S, Binder U, Skerra A, Lee AS, Haller D
Endoplasmic reticulum stress response promotes cytotoxic phenotype of CD8αβ+ intraepithelial lymphocytes in a mouse model for Crohn's disease-like ileitis.
J Immunol 189: 1510-20 (2012)
PM ID: 22753943
402: Nguyen TJ, Costa MA, Vidar EN, Shahabi A, Peric M, Hernandez AM, Chan LS, Sener SF, Wong AK
Effect of immediate reconstruction on postmastectomy surgical site infection.
Ann Surg 256: 326-33 (2012)
PM ID: 22791106
403: Limsui D, Vierkant RA, Tillmans LS, Wang AH, Weisenberger DJ, Laird PW, Lynch CF, Anderson KE, French AJ, Haile RW, Harnack LJ, Potter JD, Slager SL, Smyrk TC, Thibodeau SN, Cerhan JR, Limburg PJ
Postmenopausal hormone therapy and colorectal cancer risk by molecularly defined subtypes among older women.
Gut 61: 1299-305 (2012)
PM ID: 22027477 PMC3584677 NIHMS441004
404: Kim K, Jeong KW, Kim H, Choi J, Lu W, Stallcup MR, An W
Functional interplay between p53 acetylation and H1.2 phosphorylation in p53-regulated transcription.
Oncogene 31: 4290-301 (2012)
PM ID: 22249259 PMC3330162 NIHMS341053
405: Farnham PJ
Thematic minireview series on results from the ENCODE Project: Integrative global analyses of regulatory regions in the human genome.
J Biol Chem 287: 30885-7 (2012)
PM ID: 22451669 PMC3438920
406: Breton CV, Salam MT, Wang X, Byun HM, Siegmund KD, Gilliland FD
Particulate matter, DNA methylation in nitric oxide synthase, and childhood respiratory disease.
Environ Health Perspect 120: 1320-6 (2012)
PM ID: 22591701 PMC3440108
407: Brulois KF, Chang H, Lee AS, Ensser A, Wong LY, Toth Z, Lee SH, Lee HR, Myoung J, Ganem D, Oh TK, Kim JF, Gao SJ, Jung JU
Construction and manipulation of a new Kaposi's sarcoma-associated herpesvirus bacterial artificial chromosome clone.
J Virol 86: 9708-20 (2012)
PM ID: 22740391 PMC3446615
408: Lan X, Witt H, Katsumura K, Ye Z, Wang Q, Bresnick EH, Farnham PJ, Jin VX
Integration of Hi-C and ChIP-seq data reveals distinct types of chromatin linkages.
Nucleic Acids Res 40: 7690-704 (2012)
PM ID: 22675074 PMC3439894
409: Cancer Genome Atlas Research Network , Hammerman PS, Hayes DN, Wilkerson MD, Schultz N, Bose R, Chu A, Collisson EA, Cope L, Creighton CJ, Getz G, Herman JG, Johnson BE, Kucherlapati R, Ladanyi M, Maher CA, Robertson G, Sander C, Shen R, Sinha R, Sivachenko A, Thomas RK, Travis WD, Tsao MS, Weinstein JN, Wigle DA, Baylin SB, Govindan R, Meyerson M
Comprehensive genomic characterization of squamous cell lung cancers.
Nature 489: 519-25 (2012)
PM ID: 22960745 PMC3466113 NIHMS392594
410: Li J, Jiang TX, Hughes MW, Wu P, Yu J, Widelitz RB, Fan G, Chuong CM
Progressive Alopecia Reveals Decreasing Stem Cell Activation Probability during Aging of Mice with Epidermal Deletion of DNA Methyltransferase 1.
J Invest Dermatol : (2012)
PM ID: 22992801
411: Pratt MR
Small-molecule reprogramming of cancer metabolism.
Chem Biol 19: 1084-5 (2012)
PM ID: 22999876
412: Landt SG, Marinov GK, Kundaje A, Kheradpour P, Pauli F, Batzoglou S, Bernstein BE, Bickel P, Brown JB, Cayting P, Chen Y, Desalvo G, Epstein C, Fisher-Aylor KI, Euskirchen G, Gerstein M, Gertz J, Hartemink AJ, Hoffman MM, Iyer VR, Jung YL, Karmakar S, Kellis M, Kharchenko PV, Li Q, Liu T, Liu XS, Ma L, Milosavljevic A, Myers RM, Park PJ, Pazin MJ, Perry MD, Raha D, Reddy TE, Rozowsky J, Shoresh N, Sidow A, Slattery M, Stamatoyannopoulos JA, Tolstorukov MY, White KP, Xi S, Farnham PJ, Lieb JD, Wold BJ, Snyder M
ChIP-seq guidelines and practices of the ENCODE and modENCODE consortia.
Genome Res 22: 1813-31 (2012)
PM ID: 22955991 PMC3431496
413: Gerstein MB, Kundaje A, Hariharan M, Landt SG, Yan KK, Cheng C, Mu XJ, Khurana E, Rozowsky J, Alexander R, Min R, Alves P, Abyzov A, Addleman N, Bhardwaj N, Boyle AP, Cayting P, Charos A, Chen DZ, Cheng Y, Clarke D, Eastman C, Euskirchen G, Frietze S, Fu Y, Gertz J, Grubert F, Harmanci A, Jain P, Kasowski M, Lacroute P, Leng J, Lian J, Monahan H, O'Geen H, Ouyang Z, Partridge EC, Patacsil D, Pauli F, Raha D, Ramirez L, Reddy TE, Reed B, Shi M, Slifer T, Wang J, Wu L, Yang X, Yip KY, Zilberman-Schapira G, Batzoglou S, Sidow A, Farnham PJ, Myers RM, Weissman SM, Snyder M
Architecture of the human regulatory network derived from ENCODE data.
Nature 489: 91-100 (2012)
PM ID: 22955619
414: Lan X, Farnham PJ, Jin VX
Uncovering transcription factor modules using one- and three-dimensional analyses.
J Biol Chem 287: 30914-21 (2012)
PM ID: 22952238 PMC3438924
415: Kage H, Borok Z
EMT and interstitial lung disease: a mysterious relationship.
Curr Opin Pulm Med 18: 517-23 (2012)
PM ID: 22854509
416: Cox SG, Kim H, Garnett AT, Medeiros DM, An W, Crump JG
An essential role of variant histone H3.3 for ectomesenchyme potential of the cranial neural crest.
PLoS Genet 8: e1002938 (2012)
PM ID: 23028350 PMC3447937
417: Yashar P, Zada G, Harris B, Giannotta SL
Extent of resection and early postoperative outcomes following removal of cystic vestibular schwannomas: surgical experience over a decade and review of the literature.
Neurosurg Focus 33: E13 (2012)
PM ID: 22937847
418: Puri AS, Zada G, Zarzour H, Laws E, Frerichs K
Cerebral vasospasm after transsphenoidal resection of pituitary macroadenomas: report of 3 cases and review of the literature.
Neurosurgery 71: 173-80; discussion 180-1 (2012)
PM ID: 22249952
419: Lucas JW, Zada G
Imaging of the pituitary and parasellar region.
Semin Neurol 32: 320-31 (2012)
PM ID: 23361479
420: Coetzee SG, Rhie SK, Berman BP, Coetzee GA, Noushmehr H
FunciSNP: an R/bioconductor tool integrating functional non-coding data sets with genetic association studies to identify candidate regulatory SNPs.
Nucleic Acids Res 40: e139 (2012)
PM ID: 22684628 PMC3467035
421: Cortessis VK, Thomas DC, Levine AJ, Breton CV, Mack TM, Siegmund KD, Haile RW, Laird PW
Environmental epigenetics: prospects for studying epigenetic mediation of exposure-response relationships.
Hum Genet 131: 1565-89 (2012)
PM ID: 22740325 PMC3432200
422: Trotta AP, Need EF, Butler LM, Selth LA, O'Loughlin MA, Coetzee GA, Tilley WD, Buchanan G
Subdomain structure of the co-chaperone SGTA and activity of its androgen receptor client.
J Mol Endocrinol 49: 57-68 (2012)
PM ID: 22693264
423: Gundimeda U, McNeill TH, Elhiani AA, Schiffman JE, Hinton DR, Gopalakrishna R
Green tea polyphenols precondition against cell death induced by oxygen-glucose deprivation via stimulation of laminin receptor, generation of reactive oxygen species, and activation of protein kinase Cε.
J Biol Chem 287: 34694-708 (2012)
PM ID: 22879598 PMC3464573
424: Zhang S, Liu CC, Li W, Shen H, Laird PW, Zhou XJ
Discovery of multi-dimensional modules by integrative analysis of cancer genomic data.
Nucleic Acids Res 40: 9379-91 (2012)
PM ID: 22879375 PMC3479191
425: Koboldt DC, Fulton RS, McLellan MD, Schmidt H, Kalicki-Veizer J, McMichael JF, Fulton LL, Dooling DJ, Ding L, Mardis ER, Wilson RK, Ally A, Balasundaram M, Butterfield YS, Carlsen R, Carter C, Chu A, Chuah E, Chun HJ, Coope RJ, Dhalla N, Guin R, Hirst C, Hirst M, Holt RA, Lee D, Li HI, Mayo M, Moore RA, Mungall AJ, Pleasance E, Robertson A, Schein JE, Shafiei A, Sipahimalani P, Slobodan JR, Stoll D, Tam A, Thiessen N, Varhol RJ, Wye N, Zeng T, Zhao Y, Birol I, Jones SJ, Marra MA, Cherniack AD, Saksena G, Onofrio RC, Pho NH, Carter SL, Schumacher SE, Tabak B, Hernandez B, Gentry J, Nguyen H, Crenshaw A, Ardlie K, Beroukhim R, Winckler W, Getz G, Gabriel SB, Meyerson M, Chin L, Park PJ, Kucherlapati R, Hoadley KA, Auman J, Fan C, Turman YJ, Shi Y, Li L, Topal MD, He X, Chao HH, Prat A, Silva GO, Iglesia MD, Zhao W, Usary J, Berg JS, Adams M, Booker J, Wu J, Gulabani A, Bodenheimer T, Hoyle AP, Simons JV, Soloway MG, Mose LE, Jefferys SR, Balu S, Parker JS, Hayes D, Perou CM, Malik S, Mahurkar S, Shen H, Weisenberger DJ, Triche T, Lai PH, Bootwalla MS, Maglinte DT, Berman BP, Van Den Berg DJ, Baylin SB, Laird PW, Creighton CJ, Donehower LA, Getz G, Noble M, Voet D, Saksena G, Gehlenborg N, DiCara D, Zhang J, Zhang H, Wu CJ, Liu SY, Lawrence MS, Zou L, Sivachenko A, Lin P, Stojanov P, Jing R, Cho J, Sinha R, Park RW, Nazaire MD, Robinson J, Thorvaldsdottir H, Mesirov J, Park PJ, Chin L, Reynolds S, Kreisberg RB, Bernard B, Bressler R, Erkkila T, Lin J, Thorsson V, Zhang W, Shmulevich I, Ciriello G, Weinhold N, Schultz N, Gao J, Cerami E, Gross B, Jacobsen A, Sinha R, Aksoy B, Antipin Y, Reva B, Shen R, Taylor BS, Ladanyi M, Sander C, Anur P, Spellman PT, Lu Y, Liu W, Verhaak RR, Mills GB, Akbani R, Zhang N, Broom BM, Casasent TD, Wakefield C, Unruh AK, Baggerly K, Coombes K, Weinstein JN, Haussler D, Benz CC, Stuart JM, Benz SC, Zhu J, Szeto CC, Scott GK, Yau C, Paull EO, Carlin D, Wong C, Sokolov A, Thusberg J, Mooney S, Ng S, Goldstein TC, Ellrott K, Grifford M, Wilks C, Ma S, Craft B, Yan C, Hu Y, Meerzaman D, Gastier-Foster JM, Bowen J, Ramirez NC, Black AD, Pyatt RE, White P, Zmuda EJ, Frick J, Lichtenberg TM, Brookens R, George MM, Gerken MA, Harper HA, Leraas KM, Wise LJ, Tabler TR, McAllister C, Barr T, Hart-Kothari M, Tarvin K, Saller C, Sandusky G, Mitchell C, Iacocca MV, Brown J, Rabeno B, Czerwinski C, Petrelli N, Dolzhansky O, Abramov M, Voronina O, Potapova O, Marks JR, Suchorska WM, Murawa D, Kycler W, Ibbs M, Korski K, Spychała A, Murawa P, Brzeziński JJ, Perz H, Łaźniak R, Teresiak M, Tatka H, Leporowska E, Bogusz-Czerniewicz M, Malicki J, Mackiewicz A, Wiznerowicz M, Le XV, Kohl B, Nguyen VT, Thorp R, Nguyen VB, Sussman H, Bui DP, Hajek R, Nguyen PH, Tran VT, Huynh QT, Khan KZ, Penny R, Mallery D, Curley E, Shelton C, Yena P, Ingle JN, Couch FJ, Lingle WL, King TA, Gonzalez-Angulo AM, Mills GB, Dyer MD, Liu S, Meng X, Patangan M, Waldman F, Stöppler H, Rathmell W, Thorne L, Huang M, Boice L, Hill A, Morrison C, Gaudioso C, Bshara W, Daily K, Egea SC, Pegram M, Gomez-Fernandez C, Dhir R, Bhargava R, Brufsky A, Shriver CD, Hooke JA, Campbell JL, Mural RJ, Hu H, Somiari S, Larson C, Deyarmin B, Kvecher L, Kovatich AJ, Ellis MJ, King TA, Hu H, Couch FJ, Mural RJ, Stricker T, White K, Olopade O, Ingle JN, Luo C, Chen Y, Marks JR, Waldman F, Wiznerowicz M, Bose R, Chang LW, Beck AH, Gonzalez-Angulo AM, Pihl T, Jensen M, Sfeir R, Kahn A, Chu A, Kothiyal P, Wang Z, Snyder E, Pontius J, Ayala B, Backus M, Walton J, Baboud J, Berton D, Nicholls M, Srinivasan D, Raman R, Girshik S, Kigonya P, Alonso S, Sanbhadti R, Barletta S, Pot D, Sheth M, Demchok JA, Shaw KR, Yang L, Eley G, Ferguson ML, Tarnuzzer RW, Zhang J, Dillon LA, Buetow K, Fielding P, Ozenberger BA, Guyer MS, Sofia HJ, Palchik JD, Cancer Genome Atlas Network
Comprehensive molecular portraits of human breast tumours.
Nature 490: 61-70 (2012)
PM ID: 23000897 PMC3465532 NIHMS393293
426: Tewari AK, Yardimci GG, Shibata Y, Sheffield NC, Song L, Taylor BS, Georgiev SG, Coetzee GA, Ohler U, Furey TS, Crawford GE, Febbo PG
Chromatin accessibility reveals insights into androgen receptor activation and transcriptional specificity.
Genome Biol 13: R88 (2012)
PM ID: 23034120 PMC3491416
427: Wang XM, Yik WY, Zhang P, Lu W, Dranchak PK, Shibata D, Steinberg SJ, Hacia JG
The gene expression profiles of induced pluripotent stem cells from individuals with childhood cerebral adrenoleukodystrophy are consistent with proposed mechanisms of pathogenesis.
Stem Cell Res Ther 3: 39 (2012)
PM ID: 23036268 PMC3580430
428: Lucas JW, Zada G
Endoscopic surgery for pituitary tumors.
Neurosurg Clin N Am 23: 555-69 (2012)
PM ID: 23040743
429: Ishii M, Arias AC, Liu L, Chen YB, Bronner ME, Maxson RE
A stable cranial neural crest cell line from mouse.
Stem Cells Dev 21: 3069-80 (2012)
PM ID: 22889333 PMC3495126
430: Tiozzo C, Carraro G, Al Alam D, Baptista S, Danopoulos S, Li A, Lavarreda-Pearce M, Li C, De Langhe S, Chan B, Borok Z, Bellusci S, Minoo P
Mesodermal Pten inactivation leads to alveolar capillary dysplasia- like phenotype.
J Clin Invest 122: 3862-72 (2012)
PM ID: 23023706 PMC3484434
431: Chen Y, Bates DL, Dey R, Chen PH, Machado AC, Laird-Offringa IA, Rohs R, Chen L
DNA binding by GATA transcription factor suggests mechanisms of DNA looping and long-range gene regulation.
Cell Rep 2: 1197-206 (2012)
PM ID: 23142663
432: Bittencourt D, Wu DY, Jeong KW, Gerke DS, Herviou L, Ianculescu I, Chodankar R, Siegmund KD, Stallcup MR
G9a functions as a molecular scaffold for assembly of transcriptional coactivators on a subset of glucocorticoid receptor target genes.
Proc Natl Acad Sci U S A 109: 19673-8 (2012)
PM ID: 23151507 PMC3511704
433: Nielsen CB, Younesy H, O'Geen H, Xu X, Jackson AR, Milosavljevic A, Wang T, Costello JF, Hirst M, Farnham PJ, Jones SJ
Spark: a navigational paradigm for genomic data exploration.
Genome Res 22: 2262-9 (2012)
PM ID: 22960372 PMC3483555
434: Khalessi AA, Zada G, Wang MY, Calland JF
Introduction: quality process improvement and the neurosurgeon.
Neurosurg Focus 33: Introduction (2012)
PM ID: 23116105
435: Pfaffenbach KT, Pong M, Morgan TE, Wang H, Ott K, Zhou B, Longo VD, Lee AS
GRP78/BiP is a novel downstream target of IGF-1 receptor mediated signaling.
J Cell Physiol 227: 3803-11 (2012)
PM ID: 22422508 PMC3421054 NIHMS364068
436: Li J, Jiang TX, Hughes MW, Wu P, Widelitz RB, Fan G, Chuong CM
Progressive alopecia reveals decreasing stem cell activation probability during aging of mice with epidermal deletion of DNA methyltransferase 1.
J Invest Dermatol 132: 2681-90 (2012)
PM ID: 22763785 PMC3465630 NIHMS378674
437: Yue Z, Jiang TX, Wu P, Widelitz RB, Chuong CM
Sprouty/FGF signaling regulates the proximal-distal feather morphology and the size of dermal papillae.
Dev Biol 372: 45-54 (2012)
PM ID: 23000358 PMC3586415 NIHMS408974
438: Kelly TK, Liu Y, Lay FD, Liang G, Berman BP, Jones PA
Genome-wide mapping of nucleosome positioning and DNA methylation within individual DNA molecules.
Genome Res 22: 2497-506 (2012)
PM ID: 22960375 PMC3514679
439: Siddiq A, Couch FJ, Chen GK, Lindström S, Eccles D, Millikan RC, Michailidou K, Stram DO, Beckmann L, Rhie SK, Ambrosone CB, Aittomäki K, Amiano P, Apicella C, Australian Breast Cancer Tissue Bank Investigators , Baglietto L, Bandera EV, Beckmann MW, Berg CD, Bernstein L, Blomqvist C, Brauch H, Brinton L, Bui QM, Buring JE, Buys SS, Campa D, Carpenter JE, Chasman DI, Chang-Claude J, Chen C, Clavel-Chapelon F, Cox A, Cross SS, Czene K, Deming SL, Diasio RB, Diver WR, Dunning AM, Durcan L, Ekici AB, Fasching PA, Familial Breast Cancer Study , Feigelson HS, Fejerman L, Figueroa JD, Fletcher O, Flesch-Janys D, Gaudet MM, GENICA Consortium , Gerty SM, Rodriguez-Gil JL, Giles GG, van Gils CH, Godwin AK, Graham N, Greco D, Hall P, Hankinson SE, Hartmann A, Hein R, Heinz J, Hoover RN, Hopper JL, Hu JJ, Huntsman S, Ingles SA, Irwanto A, Isaacs C, Jacobs KB, John EM, Justenhoven C, Kaaks R, Kolonel LN, Coetzee GA, Lathrop M, Le Marchand L, Lee AM, Lee IM, Lesnick T, Lichtner P, Liu J, Lund E, Makalic E, Martin NG, McLean CA, Meijers-Heijboer H, Meindl A, Miron P, Monroe KR, Montgomery GW, Müller-Myhsok B, Nickels S, Nyante SJ, Olswold C, Overvad K, Palli D, Park DJ, Palmer JR, Pathak H, Peto J, Pharoah P, Rahman N, Rivadeneira F, Schmidt DF, Schmutzler RK, Slager S, Southey MC, Stevens KN, Sinn HP, Press MF, Ross E, Riboli E, Ridker PM, Schumacher FR, Severi G, Dos Santos Silva I, Stone J, Sund M, Tapper WJ, Thun MJ, Travis RC, Turnbull C, Uitterlinden AG, Waisfisz Q, Wang X, Wang Z, Weaver J, Schulz-Wendtland R, Wilkens LR, Van Den Berg D, Zheng W, Ziegler RG, Ziv E, Nevanlinna H, Easton DF, Hunter DJ, Henderson BE, Chanock SJ, Garcia-Closas M, Kraft P, Haiman CA, Vachon CM
A meta-analysis of genome-wide association studies of breast cancer identifies two novel susceptibility loci at 6q14 and 20q11.
Hum Mol Genet 21: 5373-84 (2012)
PM ID: 22976474 PMC3510753
440: Beck S, Bernstein BE, Campbell RM, Costello JF, Dhanak D, Ecker JR, Greally JM, Issa JP, Laird PW, Polyak K, Tycko B, Jones PA, AACR Cancer Epigenome Task Force
A blueprint for an international cancer epigenome consortium. A report from the AACR Cancer Epigenome Task Force.
Cancer Res 72: 6319-24 (2012)
PM ID: 23188507
441: Marotta NP, Cherwien CA, Abeywardana T, Pratt MR
O-GlcNAc modification prevents peptide-dependent acceleration of α-synuclein aggregation.
Chembiochem 13: 2665-70 (2012)
PM ID: 23143740
442: Han A, Bandyopadhyay B, Jayaprakash P, Lua I, Sahu D, Chen M, Woodley DT, Li W
The anti-motility signaling mechanism of TGFβ3 that controls cell traffic during skin wound healing.
Biol Open 1: 1169-77 (2012)
PM ID: 23259050 PMC3522877
443: Andreu-Vieyra CV, Liang G
Nucleosome occupancy and gene regulation during tumorigenesis.
Adv Exp Med Biol 754: 109-34 (2013)
PM ID: 22956498
444: Wu H, Chen L, Zhang X, Zhou Q, Li JM, Berger S, Borok Z, Zhou B, Xiao Z, Yin H, Liu M, Wang Y, Jin J, Blackburn MR, Xia Y, Zhang W
Aqp5 is a new transcriptional target of Dot1a and a regulator of Aqp2.
PLoS One 8: e53342 (2013)
PM ID: 23326416 PMC3542343
445: Zaro BW, Hang HC, Pratt MR
Incorporation of unnatural sugars for the identification of glycoproteins.
Methods Mol Biol 951: 57-67 (2013)
PM ID: 23296524
446: Zada G
Diagnosis and Multimodality Management of Cushing's Disease: A Practical Review.
Int J Endocrinol 2013: 893781 (2013)
PM ID: 23401686 PMC3562580
447: Gao F, Shi L, Russin J, Zeng L, Chang X, He S, Chen TC, Giannotta SL, Weisenberger DJ, Zada G, Mack WJ, Wang K
DNA methylation in the malignant transformation of meningiomas.
PLoS One 8: e54114 (2013)
PM ID: 23349797 PMC3551961
448: Li W, Tsen F, Sahu D, Bhatia A, Chen M, Multhoff G, Woodley DT
Extracellular Hsp90 (eHsp90) as the actual target in clinical trials: intentionally or unintentionally.
Int Rev Cell Mol Biol 303: 203-35 (2013)
PM ID: 23445811
449: Easton D, Eeles R, Muir K, Giles G, Wiklund F, Gronberg H, Haiman C, Schleutker J, Weischer M, Travis R, Neal D, Pharoah P, Khaw KT, Stanford JL, Blot WJ, Thibodeau S, Maier C, Kibel AS, Cybulski C, Cannon-Albright L, Brenner H, Park J, Kaneva R, Batra J, Teixeira MR, Ghoussaini M, Kote-Jarai Z, Al Olama AA, Benlloch S, Bowtell D, Gertig D, Green A, Defazio A, Webb P, Stuart-Harris R, Kirsten F, Rutovitz J, Clingan P, Glasgow A, Proietto A, Braye S, Otton G, Shannon J, Bonaventura T, Stewart J, Begbie S, Friedlander M, Bell D, Baron-Hay S, Ferrier A, Gard G, Nevell D, Pavlakis N, Valmadre S, Young B, Camaris C, Crouch R, Edwards L, Hacker N, Marsden D, Robertson G, Beale P, Beith J, Carter J, Dalrymple C, Houghton R, Russell P, Anderson L, Links M, Grygiel J, Hill J, Brand A, Byth K, Jaworski R, Harnett P, Sharma R, Wain G, Purdie D, Whiteman D, Ward B, Papadimos D, Crandon A, Cummings M, Horwood K, Obermair A, Perrin L, Wyld D, Nicklin J, Davy M, Oehler MK, Hall C, Dodd T, Healy T, Pittman K, Henderson D, Miller J, Pierdes J, Achan A, Blomfield P, Challis D, McIntosh R, Parker A, Brown B, Rome R, Allen D, Grant P, Hyde S, Laurie R, Robbie M, Healy D, Jobling T, Manolitsas T, McNealage J, Rogers P, Susil B, Sumithran E, Simpson I, Haviv I, Phillips K, Rischin D, Fox S, Johnson D, Lade S, Waring P, Loughrey M, O'Callaghan N, Murray B, Mileshkin L, Allan P, Billson V, Pyman J, Neesham D, Quinn M, Hamilton A, Underhill C, Bell R, Ng LF, Blum R, Ganju V, Hammond I, McCartney A, Stewart C, Leung Y, Buck M, Zeps N, Whiteman DC, Webb PM, Phil D, Hayward NK, Parsons PG, Purdie DM, Smithers B, Gotley D, Clouston A, Brown I, Moore S, Harrap K, Sadkowski T, O'Brien S, Minehan E, Roffe D, O'Keefe S, Lipshut S, Connor G, Berry H, Walker F, Barnes T, Thomas J, Terry L, Connard M, Bowes L, Malt M, White J, Mosse C, Tait N, Bambach C, Biankan A, Brancatisano R, Coleman M, Cox M, Deane S, Falk GL, Gallagher J, Hollands M, Hugh T, Hunt D, Jorgensen J, Martin C, Richardson M, Smith G, Smith R, Storey D, Avramovic J, Croese J, D'Arcy J, Fairley S, Hansen J, Masson J, Nathanson L, O'Loughlin B, Rutherford L, Turner R, Windsor M, Bessell J, Devitt P, Jamieson G, Watson D, Blamey S, Boussioutas A, Cade R, Crosthwaite G, Faragher I, Gribbin J, Hebbard G, Kiroff G, Mann B, Millar B, O'Brien P, Thomas R, Wood S, Shen H, Fridley BL, Song H, Lawrenson K, Cunningham JM, Ramus SJ, Cicek MS, Tyrer J, Stram D, Larson MC, Köbel M, PRACTICAL Consortium , Ziogas A, Zheng W, Yang HP, Wu AH, Wozniak EL, Woo YL, Winterhoff B, Wik E, Whittemore AS, Wentzensen N, Weber RP, Vitonis AF, Vincent D, Vierkant RA, Vergote I, Van Den Berg D, van Altena AM, Tworoger SS, Thompson PJ, Tessier DC, Terry KL, Teo SH, Templeman C, Stram DO, Southey MC, Sieh W, Siddiqui N, Shvetsov YB, Shu XO, Shridhar V, Wang-Gohrke S, Severi G, Schwaab I, Salvesen HB, Rzepecka IK, Runnebaum IB, Rossing MA, Rodriguez-Rodriguez L, Risch HA, Renner SP, Poole EM, Pike MC, Phelan CM, Pelttari LM, Pejovic T, Paul J, Orlow I, Omar SZ, Olson SH, Odunsi K, Nickels S, Nevanlinna H, Ness RB, Narod SA, Nakanishi T, Moysich KB, Monteiro AN, Moes-Sosnowska J, Modugno F, Menon U, McLaughlin JR, McGuire V, Matsuo K, Adenan NA, Massuger LF, Lurie G, Lundvall L, Lubinski J, Lissowska J, Levine DA, Leminen A, Lee AW, Le ND, Lambrechts S, Lambrechts D, Kupryjanczyk J, Krakstad C, Konecny GE, Kjaer SK, Kiemeney LA, Kelemen LE, Keeney GL, Karlan BY, Karevan R, Kalli KR, Kajiyama H, Ji BT, Jensen A, Jakubowska A, Iversen E, Hosono S, Høgdall CK, Høgdall E, Hoatlin M, Hillemanns P, Heitz F, Hein R, Harter P, Halle MK, Hall P, Gronwald J, Gore M, Goodman MT, Giles GG, Gentry-Maharaj A, Garcia-Closas M, Flanagan JM, Fasching PA, Ekici AB, Edwards R, Eccles D, Easton DF, Dürst M, du Bois A, Dörk T, Doherty JA, Despierre E, Dansonka-Mieszkowska A, Cybulski C, Cramer DW, Cook LS, Chen X, Charbonneau B, Chang-Claude J, Campbell I, Butzow R, Bunker CH, Brueggmann D, Brown R, Brooks-Wilson A, Brinton LA, Bogdanova N, Block MS, Benjamin E, Beesley J, Beckmann MW, Bandera EV, Baglietto L, Bacot F, Armasu SM, Antonenkova N, Anton-Culver H, Aben KK, Liang D, Wu X, Lu K, Hildebrandt MA, Australian Ovarian Cancer Study Group , Australian Cancer Study , Schildkraut JM, Sellers TA, Huntsman D, Berchuck A, Chenevix-Trench G, Gayther SA, Pharoah PD, Laird PW, Goode EL, Pearce CL
Epigenetic analysis leads to identification of HNF1B as a subtype-specific susceptibility gene for ovarian cancer.
Nat Commun 4: 1628 (2013)
PM ID: 23535649 PMC3848248 NIHMS483288
450: Whiteman DC, Webb PM, Phil D, Green AC, Hayward NK, Parsons PG, Purdie DM, Smithers B, Gotley D, Clouston A, Brown I, Moore S, Harrap K, Sadkowski T, O'Brien S, Minehan E, Roffe D, O'Keefe S, Lipshut S, Connor G, Berry H, Walker F, Barnes T, Thomas J, Terry L, Connard M, Bowes L, Malt M, White J, Mosse C, Tait N, Bambach C, Biankan A, Brancatisano R, Coleman M, Cox M, Deane S, Falk GL, Gallagher J, Hollands M, Hugh T, Hunt D, Jorgensen J, Martin C, Richardson M, Smith G, Smith R, Storey D, Avramovic J, Croese J, D'Arcy J, Fairley S, Hansen J, Masson J, Nathanson L, O'Loughlin B, Rutherford L, Turner R, Windsor M, Bessell J, Devitt P, Jamieson G, Watson D, Blamey S, Boussioutas A, Cade R, Crosthwaite G, Faragher I, Gribbin J, Hebbard G, Kiroff G, Mann B, Millar B, O'Brien P, Thomas R, Wood S, Archer S, Faulkner K, Hamdorf J, Stuart-Harris R, Bowtell D, Gertig D, Green A, Defazio A, Webb P, Kirsten F, Rutovitz J, Clingan P, Glasgow A, Proietto A, Braye S, Otton G, Shannon J, Bonaventura T, Stewart J, Begbie S, Friedlander M, Bell D, Baron-Hay S, Ferrier A, Gard G, Nevell D, Pavlakis N, Valmadre S, Young B, Camaris C, Crouch R, Edwards L, Hacker N, Marsden D, Robertson G, Beale P, Beith J, Carter J, Dalrymple C, Houghton R, Russell P, Anderson L, Links M, Grygiel J, Hill J, Brand A, Byth K, Jaworski R, Harnett P, Sharma R, Wain G, Purdie D, Whiteman D, Ward B, Papadimos D, Crandon A, Cummings M, Horwood K, Obermair A, Perrin L, Wyld D, Nicklin J, Davy M, Oehler MK, Hall C, Dodd T, Healy T, Pittman K, Henderson D, Miller J, Pierdes J, Achan A, Blomfield P, Challis D, McIntosh R, Parker A, Brown B, Rome R, Allen D, Grant P, Hyde S, Laurie R, Robbie M, Healy D, Jobling T, Manolitsas T, McNealage J, Rogers P, Susil B, Sumithran E, Simpson I, Haviv I, Phillips K, Rischin D, Fox S, Johnson D, Lade S, Waring P, Loughrey M, O'Callaghan N, Murray B, Mileshkin L, Allan P, Billson V, Pyman J, Neesham D, Quinn M, Hamilton A, Underhill C, Bell R, Ng LF, Blum R, Ganju V, Hammond I, McCartney A, Stewart C, Leung Y, Buck M, Zeps N, Andrulis IL, Caldes T, Caligo MA, Sinilnikova O, Hansen TV, Rookus M, Hogervorst F, Jakubowska A, Lubinski J, Peock S, Chenevix-Trench G, Nathanson KL, Domchek S, Nevanlinna H, Offit K, Osorio A, Benitez J, Radice P, Singer CF, Schmutzler R, Godwin A, Blanco I, Lazaro C, Montagna M, Beattie MS, Antoniou AC, Easton DF, Couch FJ, Permuth-Wey J, Lawrenson K, Shen HC, Velkova A, Tyrer JP, Chen Z, Lin HY, Chen YA, Tsai YY, Qu X, Ramus SJ, Karevan R, Lee J, Lee N, Larson MC, Aben KK, Anton-Culver H, Antonenkova N, Antoniou AC, Armasu SM, Australian Cancer Study , Australian Ovarian Cancer Study , Bacot F, Baglietto L, Bandera EV, Barnholtz-Sloan J, Beckmann MW, Birrer MJ, Bloom G, Bogdanova N, Brinton LA, Brooks-Wilson A, Brown R, Butzow R, Cai Q, Campbell I, Chang-Claude J, Chanock S, Chenevix-Trench G, Cheng JQ, Cicek MS, Coetzee GA, Consortium of Investigators of Modifiers of BRCA1/2 , Cook LS, Couch FJ, Cramer DW, Cunningham JM, Dansonka-Mieszkowska A, Despierre E, Doherty JA, Dörk T, du Bois A, Dürst M, Easton DF, Eccles D, Edwards R, Ekici AB, Fasching PA, Fenstermacher DA, Flanagan JM, Garcia-Closas M, Gentry-Maharaj A, Giles GG, Glasspool RM, Gonzalez-Bosquet J, Goodman MT, Gore M, Górski B, Gronwald J, Hall P, Halle MK, Harter P, Heitz F, Hillemanns P, Hoatlin M, Høgdall CK, Høgdall E, Hosono S, Jakubowska A, Jensen A, Jim H, Kalli KR, Karlan BY, Kaye SB, Kelemen LE, Kiemeney LA, Kikkawa F, Konecny GE, Krakstad C, Kjaer SK, Kupryjanczyk J, Lambrechts D, Lambrechts S, Lancaster JM, Le ND, Leminen A, Levine DA, Liang D, Lim BK, Lin J, Lissowska J, Lu KH, Lubinski J, Lurie G, Massuger LF, Matsuo K, McGuire V, McLaughlin JR, Menon U, Modugno F, Moysich KB, Nakanishi T, Narod SA, Nedergaard L, Ness RB, Nevanlinna H, Nickels S, Noushmehr H, Odunsi K, Olson SH, Orlow I, Paul J, Pearce CL, Pejovic T, Pelttari LM, Pike MC, Poole EM, Raska P, Renner SP, Risch HA, Rodriguez-Rodriguez L, Rossing MA, Rudolph A, Runnebaum IB, Rzepecka IK, Salvesen HB, Schwaab I, Severi G, Shridhar V, Shu XO, Shvetsov YB, Sieh W, Song H, Southey MC, Spiewankiewicz B, Stram D, Sutphen R, Teo SH, Terry KL, Tessier DC, Thompson PJ, Tworoger SS, van Altena AM, Vergote I, Vierkant RA, Vincent D, Vitonis AF, Wang-Gohrke S, Palmieri Weber R, Wentzensen N, Whittemore AS, Wik E, Wilkens LR, Winterhoff B, Woo YL, Wu AH, Xiang YB, Yang HP, Zheng W, Ziogas A, Zulkifli F, Phelan CM, Iversen E, Schildkraut JM, Berchuck A, Fridley BL, Goode EL, Pharoah PD, Monteiro AN, Sellers TA, Gayther SA
Identification and molecular characterization of a new ovarian cancer susceptibility locus at 17q21.31.
Nat Commun 4: 1627 (2013)
PM ID: 23535648 PMC3709460 NIHMS447293
451: Gao F, Wei Z, An W, Wang K, Lu W
The interactomes of POU5F1 and SOX2 enhancers in human embryonic stem cells.
Sci Rep 3: 1588 (2013)
PM ID: 23549118
452: Rhie SK, Coetzee SG, Noushmehr H, Yan C, Kim JM, Haiman CA, Coetzee GA
Comprehensive functional annotation of seventy-one breast cancer risk Loci.
PLoS One 8: e63925 (2013)
PM ID: 23717510 PMC3661550
453: Liu SV, Fabbri M, Gitlitz BJ, Laird-Offringa IA
Epigenetic therapy in lung cancer.
Front Oncol 3: 135 (2013)
PM ID: 23755372 PMC3667274
454: Li A, Chan B, Felix JC, Xing Y, Li M, Brody SL, Borok Z, Li C, Minoo P
Tissue-dependent consequences of Apc inactivation on proliferation and differentiation of ciliated cell progenitors via Wnt and notch signaling.
PLoS One 8: e62215 (2013)
PM ID: 23646120 PMC3639955
455: Li A, Chan B, Felix JC, Xing Y, Li M, Brody SL, Zhang Y, Holtzman MJ, Borok Z, Li C, Minoo P
Correction: Tissue-Dependent Consequences of Apc Inactivation on Proliferation and Differentiation of Ciliated Cell Progenitors via Wnt and Notch Signaling.
PLoS One 8: (2013)
PM ID: 23750190
456: Chihara Y, Kanai Y, Fujimoto H, Sugano K, Kawashima K, Liang G, Jones PA, Fujimoto K, Kuniyasu H, Hirao Y
Diagnostic markers of urothelial cancer based on DNA methylation analysis.
BMC Cancer 13: 275 (2013)
PM ID: 23735005 PMC3691617
457: Wang R, Hsu HK, Blattler A, Wang Y, Lan X, Wang Y, Hsu PY, Leu YW, Huang TH, Farnham PJ, Jin VX
LOcating non-unique matched tags (LONUT) to improve the detection of the enriched regions for ChIP-seq data.
PLoS One 8: e67788 (2013)
PM ID: 23825685 PMC3692479
458: Sherman JH, Smith ZA, Cho JM, Lim M, Colen CB, Kim CY, Wang VY, Zada G, Li G, Yang I
Neurosurgery concepts: Key perspectives on regulatory proteins, management of ossification of the posterior longitudinal ligament, and radiosurgery for intracranial lesions.
Surg Neurol Int 4: 35 (2013)
PM ID: 23607057 PMC3622379
459: Kim K, Punj V, Choi J, Heo K, Kim JM, Laird PW, An W
Gene dysregulation by histone variant H2A.Z in bladder cancer.
Epigenetics Chromatin 6: 34 (2013)
PM ID: 24279307 PMC3853418
460: Kim JM, Heo K, Choi J, Kim K, An W
The histone variant MacroH2A regulates Ca(2+) influx through TRPC3 and TRPC6 channels.
Oncogenesis 2: e77 (2013)
PM ID: 24165580 PMC3816217
461: St Pourcain B, Whitehouse AJ, Ang WQ, Warrington NM, Glessner JT, Wang K, Timpson NJ, Evans DM, Kemp JP, Ring SM, McArdle WL, Golding J, Hakonarson H, Pennell CE, Smith GD
Common variation contributes to the genetic architecture of social communication traits.
Mol Autism 4: 34 (2013)
PM ID: 24047820 PMC3853437
462: Hazelett DJ, Coetzee SG, Coetzee GA
A rare variant, which destroys a FoxA1 site at 8q24, is associated with prostate cancer risk.
Cell Cycle 12: 379-80 (2013)
PM ID: 23255135 PMC3575466 [Available on 01/15/14]
463: Lei MX, Chuong CM, Widelitz RB
Tuning Wnt signals for more or fewer hairs.
J Invest Dermatol 133: 7-9 (2013)
PM ID: 23299447 PMC3686512 NIHMS465506
464: Deliard S, Panossian S, Mentch FD, Kim CE, Hou C, Frackelton EC, Bradfield JP, Glessner JT, Zhang H, Wang K, Sleiman PM, Chiavacci RM, Berkowitz RI, Hakonarson H, Zhao J, Grant SF
The missense variation landscape of FTO, MC4R, and TMEM18 in obese children of African Ancestry.
Obesity (Silver Spring) 21: 159-63 (2013)
PM ID: 23505181 PMC3605748 NIHMS417070
465: Kandyba E, Leung Y, Chen YB, Widelitz R, Chuong CM, Kobielak K
Competitive balance of intrabulge BMP/Wnt signaling reveals a robust gene network ruling stem cell homeostasis and cyclic activation.
Proc Natl Acad Sci U S A 110: 1351-6 (2013)
PM ID: 23292934 PMC3557042
466: Luo B, Lee AS
The critical roles of endoplasmic reticulum chaperones and unfolded protein response in tumorigenesis and anticancer therapies.
Oncogene 32: 805-18 (2013)
PM ID: 22508478
467: Davis GB, Peric M, Chan LS, Wong AK, Sener SF
Identifying risk factors for surgical site infections in mastectomy patients using the National Surgical Quality Improvement Program database.
Am J Surg 205: 194-9 (2013)
PM ID: 22944390
468: Matsuo K, Gray MJ, Yang DY, Srivastava SA, Tripathi PB, Sonoda LA, Yoo EJ, Dubeau L, Lee AS, Lin YG
The endoplasmic reticulum stress marker, glucose-regulated protein-78 (GRP78) in visceral adipocytes predicts endometrial cancer progression and patient survival.
Gynecol Oncol 128: 552-9 (2013)
PM ID: 23200913
469: Zhu G, Ye R, Jung DY, Barron E, Friedline RH, Benoit VM, Hinton DR, Kim JK, Lee AS
GRP78 plays an essential role in adipogenesis and postnatal growth in mice.
FASEB J 27: 955-64 (2013)
PM ID: 23180827 PMC3574283 [Available on 03/01/14]
470: Ohiorhenuan I, Zada G
Neural prosthesis for recovery of impaired cognitive function: bridging the gap between concept and reality.
World Neurosurg 79: 409-10 (2013)
PM ID: 23369805
471: Shen H, Laird PW
Interplay between the cancer genome and epigenome.
Cell 153: 38-55 (2013)
PM ID: 23540689 PMC3648790 [Available on 03/28/14] NIHMS459754 [Available on 03/28/14]
472: Trisciuoglio D, De Luca T, Desideri M, Passeri D, Gabellini C, Scarpino S, Liang C, Orlandi A, Del Bufalo D
Removal of the BH4 domain from Bcl-2 protein triggers an autophagic process that impairs tumor growth.
Neoplasia 15: 315-27 (2013)
PM ID: 23479509 PMC3593154
473: O'Rawe J, Guangqing S, Wang W, Hu J, Bodily P, Tian L, Hakonarson H, Johnson E, Wei Z, Jiang T, Wang K, Lyon G, Wu Y
Low concordance of multiple variant-calling pipelines: practical implications for exome and genome sequencing.
Genome Med 5: 28 (2013)
PM ID: 23537139 PMC3706896
474: Liu SV, Wagle N, Zada G, Sun B, Go J, Rashtian A
Leptomeningeal carcinomatosis in sinonasal undifferentiated carcinoma.
Head Neck : (2013)
PM ID: 23471826
475: Tuchman A, Platt A, Winer J, Pham M, Giannotta S, Zada G
Endoscopic-Assisted Resection of Intracranial Epidermoid Tumors.
World Neurosurg : (2013)
PM ID: 23548848
476: Donnelly P, Bell J, Bentley D, McVean G, Ratcliffe P, Taylor J, Wilkie A, Donnelly P, Broxholme J, Buck D, Cazier JB, Cornall R, Gregory L, Knight J, Lunter G, McVean G, Taylor J, Tomlinson I, Wilkie A, Buck D, Allan C, Attar M, Green A, Gregory L, Humphray S, Kingsbury Z, Lamble S, Lonie L, Pagnamenta A, Piazza P, Polanco G, Trebes A, McVean G, Donnelly P, Cazier JB, Broxholme J, Copley R, Fiddy S, Grocock R, Hatton E, Holmes C, Hughes L, Humburg P, Kanapin A, Lise S, Lunter G, Martin H, Murray L, McCarthy D, Rimmer A, Sahgal N, Wright B, Yau C, Sharma VP, Fenwick AL, Brockop MS, McGowan SJ, Goos JA, Hoogeboom AJ, Brady AF, Jeelani NO, Lynch SA, Mulliken JB, Murray DJ, Phipps JM, Sweeney E, Tomkins SE, Wilson LC, Bennett S, Cornall RJ, Broxholme J, Kanapin A, 500 Whole-Genome Sequences (WGS500) Consortium , Johnson D, Wall SA, van der Spek PJ, Mathijssen IM, Maxson RE, Twigg SR, Wilkie AO
Mutations in TCF12, encoding a basic helix-loop-helix partner of TWIST1, are a frequent cause of coronal craniosynostosis.
Nat Genet 45: 304-7 (2013)
PM ID: 23354436 PMC3647333
477: Pohl A, El-Khoueiry A, Yang D, Zhang W, Lurje G, Ning Y, Winder T, Hu-Lieskoven S, Iqbal S, Danenberg KD, Kahn M, Teo JL, Shriki J, Stebbing J, Lenz HJ
Pharmacogenetic profiling of CD133 is associated with response rate (RR) and progression-free survival (PFS) in patients with metastatic colorectal cancer (mCRC), treated with bevacizumab-based chemotherapy.
Pharmacogenomics J 13: 173-80 (2013)
PM ID: 22231565 PMC3326190 [Available on 10/01/13] NIHMS337191 [Available on 10/01/13]
478: Pelikan RC, Iwata J, Suzuki A, Chai Y, Hacia JG
Identification of candidate downstream targets of TGFβ signaling during palate development by genome-wide transcript profiling.
J Cell Biochem 114: 796-807 (2013)
PM ID: 23060211 PMC3777336 NIHMS470529
479: Peters U, Jiao S, Schumacher FR, Hutter CM, Aragaki AK, Baron JA, Berndt SI, Bézieau S, Brenner H, Butterbach K, Caan BJ, Campbell PT, Carlson CS, Casey G, Chan AT, Chang-Claude J, Chanock SJ, Chen LS, Coetzee GA, Coetzee SG, Conti DV, Curtis KR, Duggan D, Edwards T, Fuchs CS, Gallinger S, Giovannucci EL, Gogarten SM, Gruber SB, Haile RW, Harrison TA, Hayes RB, Henderson BE, Hoffmeister M, Hopper JL, Hudson TJ, Hunter DJ, Jackson RD, Jee SH, Jenkins MA, Jia WH, Kolonel LN, Kooperberg C, Küry S, Lacroix AZ, Laurie CC, Laurie CA, Le Marchand L, Lemire M, Levine D, Lindor NM, Liu Y, Ma J, Makar KW, Matsuo K, Newcomb PA, Potter JD, Prentice RL, Qu C, Rohan T, Rosse SA, Schoen RE, Seminara D, Shrubsole M, Shu XO, Slattery ML, Taverna D, Thibodeau SN, Ulrich CM, White E, Xiang Y, Zanke BW, Zeng YX, Zhang B, Zheng W, Hsu L, Colon Cancer Family Registry and the Genetics and Epidemiology of Colorectal Cancer Consortium
Identification of Genetic Susceptibility Loci for Colorectal Tumors in a Genome-Wide Meta-analysis.
Gastroenterology 144: 799-807.e24 (2013)
PM ID: 23266556 PMC3636812 [Available on 04/01/14] NIHMS431479 [Available on 04/01/14]
480: Pandiyan K, You JS, Yang X, Dai C, Zhou XJ, Baylin SB, Jones PA, Liang G
Functional DNA demethylation is accompanied by chromatin accessibility.
Nucleic Acids Res 41: 3973-85 (2013)
PM ID: 23408854 PMC3627572
481: Patil AA, Ouellette AJ, Lu W, Zhang G
Rattusin, an intestinal α-defensin-related peptide in rats with a unique cysteine spacing pattern and salt-insensitive antibacterial activities.
Antimicrob Agents Chemother 57: 1823-31 (2013)
PM ID: 23380721 PMC3623328 [Available on 10/01/13]
482: Hoang T, Fenne IS, Madsen A, Bozickovic O, Johannessen M, Bergsvåg M, Lien EA, Stallcup MR, Sagen JV, Moens U, Mellgren G
cAMP response element-binding protein interacts with and stimulates the proteasomal degradation of the nuclear receptor coactivator GRIP1.
Endocrinology 154: 1513-27 (2013)
PM ID: 23462962
483: Triche TJ, Weisenberger DJ, Van Den Berg D, Laird PW, Siegmund KD
Low-level processing of Illumina Infinium DNA Methylation BeadArrays.
Nucleic Acids Res 41: e90 (2013)
PM ID: 23476028 PMC3627582
484: Heijmans J, van Lidth de Jeude JF, Koo BK, Rosekrans SL, Wielenga MC, van de Wetering M, Ferrante M, Lee AS, Onderwater JJ, Paton JC, Paton AW, Mommaas AM, Kodach LL, Hardwick JC, Hommes DW, Clevers H, Muncan V, van den Brink GR
ER stress causes rapid loss of intestinal epithelial stemness through activation of the unfolded protein response.
Cell Rep 3: 1128-39 (2013)
PM ID: 23545496
485: You JS, De Carvalho DD, Dai C, Liu M, Pandiyan K, Zhou XJ, Liang G, Jones PA
SNF5 is an essential executor of epigenetic regulation during differentiation.
PLoS Genet 9: e1003459 (2013)
PM ID: 23637628 PMC3636213
486: Garcia-Closas M, Couch FJ, Lindstrom S, Michailidou K, Schmidt MK, Brook MN, Orr N, Rhie SK, Riboli E, Feigelson HS, Le Marchand L, Buring JE, Eccles D, Miron P, Fasching PA, Brauch H, Chang-Claude J, Carpenter J, Godwin AK, Nevanlinna H, Giles GG, Cox A, Hopper JL, Bolla MK, Wang Q, Dennis J, Dicks E, Howat WJ, Schoof N, Bojesen SE, Lambrechts D, Broeks A, Andrulis IL, Guénel P, Burwinkel B, Sawyer EJ, Hollestelle A, Fletcher O, Winqvist R, Brenner H, Mannermaa A, Hamann U, Meindl A, Lindblom A, Zheng W, Devillee P, Goldberg MS, Lubinski J, Kristensen V, Swerdlow A, Anton-Culver H, Dörk T, Muir K, Matsuo K, Wu AH, Radice P, Teo SH, Shu XO, Blot W, Kang D, Hartman M, Sangrajrang S, Shen CY, Southey MC, Park DJ, Hammet F, Stone J, Veer LJ, Rutgers EJ, Lophatananon A, Stewart-Brown S, Siriwanarangsan P, Peto J, Schrauder MG, Ekici AB, Beckmann MW, Dos Santos Silva I, Johnson N, Warren H, Tomlinson I, Kerin MJ, Miller N, Marme F, Schneeweiss A, Sohn C, Truong T, Laurent-Puig P, Kerbrat P, Nordestgaard BG, Nielsen SF, Flyger H, Milne RL, Perez JI, Menéndez P, Müller H, Arndt V, Stegmaier C, Lichtner P, Lochmann M, Justenhoven C, Ko YD, Gene ENvironmental Interaction and breast CAncer (GENICA) Network , Muranen TA, Aittomäki K, Blomqvist C, Greco D, Heikkinen T, Ito H, Iwata H, Yatabe Y, Antonenkova NN, Margolin S, Kataja V, Kosma VM, Hartikainen JM, Balleine R, kConFab Investigators , Tseng CC, Berg DV, Stram DO, Neven P, Dieudonné AS, Leunen K, Rudolph A, Nickels S, Flesch-Janys D, Peterlongo P, Peissel B, Bernard L, Olson JE, Wang X, Stevens K, Severi G, Baglietto L, McLean C, Coetzee GA, Feng Y, Henderson BE, Schumacher F, Bogdanova NV, Labrèche F, Dumont M, Yip CH, Taib NA, Cheng CY, Shrubsole M, Long J, Pylkäs K, Jukkola-Vuorinen A, Kauppila S, Knight JA, Glendon G, Mulligan AM, Tollenaar RA, Seynaeve CM, Kriege M, Hooning MJ, van den Ouweland AM, van Deurzen CH, Lu W, Gao YT, Cai H, Balasubramanian SP, Cross SS, Reed MW, Signorello L, Cai Q, Shah M, Miao H, Chan CW, Chia KS, Jakubowska A, Jaworska K, Durda K, Hsiung CN, Wu PE, Yu JC, Ashworth A, Jones M, Tessier DC, González-Neira A, Pita G, Alonso MR, Vincent D, Bacot F, Ambrosone CB, Bandera EV, John EM, Chen GK, Hu JJ, Rodriguez-Gil JL, Bernstein L, Press MF, Ziegler RG, Millikan RM, Deming-Halverson SL, Nyante S, Ingles SA, Waisfisz Q, Tsimiklis H, Makalic E, Schmidt D, Bui M, Gibson L, Müller-Myhsok B, Schmutzler RK, Hein R, Dahmen N, Beckmann L, Aaltonen K, Czene K, Irwanto A, Liu J, Turnbull C, Familial Breast Cancer Study (FBCS) , Rahman N, Meijers-Heijboer H, Uitterlinden AG, Rivadeneira F, Australian Breast Cancer Tissue Bank (ABCTB) Investigators , Olswold C, Slager S, Pilarski R, Ademuyiwa F, Konstantopoulou I, Martin NG, Montgomery GW, Slamon DJ, Rauh C, Lux MP, Jud SM, Bruning T, Weaver J, Sharma P, Pathak H, Tapper W, Gerty S, Durcan L, Trichopoulos D, Tumino R, Peeters PH, Kaaks R, Campa D, Canzian F, Weiderpass E, Johansson M, Khaw KT, Travis R, Clavel-Chapelon F, Kolonel LN, Chen C, Beck A, Hankinson SE, Berg CD, Hoover RN, Lissowska J, Figueroa JD, Chasman DI, Gaudet MM, Diver WR, Willett WC, Hunter DJ, Simard J, Benitez J, Dunning AM, Sherman ME, Chenevix-Trench G, Chanock SJ, Hall P, Pharoah PD, Vachon C, Easton DF, Haiman CA, Kraft P
Genome-wide association studies identify four ER negative-specific breast cancer risk loci.
Nat Genet 45: 392-8, 398e1-2 (2013)
PM ID: 23535733 PMC3771695 [Available on 04/01/14] NIHMS479348 [Available on 04/01/14]
487: Lange CP, Laird PW
Clinical applications of DNA methylation biomarkers in colorectal cancer.
Epigenomics 5: 105-8 (2013)
PM ID: 23566085
488: Li A, Chen M, Jiang TX, Wu P, Nie Q, Widelitz R, Chuong CM
Shaping organs by a wingless-int/Notch/nonmuscle myosin module which orients feather bud elongation.
Proc Natl Acad Sci U S A 110: E1452-61 (2013)
PM ID: 23576731 PMC3631647
489: Heo K, Kim JS, Kim K, Kim H, Choi J, Yang K, An W
Cell-penetrating H4 tail peptides potentiate p53-mediated transactivation via inhibition of G9a and HDAC1.
Oncogene 32: 2510-20 (2013)
PM ID: 22751130
490: Bateman LA, Zaro BW, Chuh KN, Pratt MR
N-Propargyloxycarbamate monosaccharides as metabolic chemical reporters of carbohydrate salvage pathways and protein glycosylation.
Chem Commun (Camb) 49: 4328-30 (2013)
PM ID: 23235740
491: Balasubramaniam S, Comstock CE, Ertel A, Jeong KW, Stallcup MR, Addya S, McCue PA, Ostrander WF, Augello MA, Knudsen KE
Aberrant BAF57 signaling facilitates prometastatic phenotypes.
Clin Cancer Res 19: 2657-67 (2013)
PM ID: 23493350 PMC3655134 [Available on 05/15/14] NIHMS455459 [Available on 05/15/14]
492: Wu P, Wu X, Jiang TX, Elsey RM, Temple BL, Divers SJ, Glenn TC, Yuan K, Chen MH, Widelitz RB, Chuong CM
Specialized stem cell niche enables repetitive renewal of alligator teeth.
Proc Natl Acad Sci U S A 110: E2009-18 (2013)
PM ID: 23671090 PMC3670376
493: Cancer Genome Atlas Research Network , Kandoth C, Schultz N, Cherniack AD, Akbani R, Liu Y, Shen H, Robertson AG, Pashtan I, Shen R, Benz CC, Yau C, Laird PW, Ding L, Zhang W, Mills GB, Kucherlapati R, Mardis ER, Levine DA
Integrated genomic characterization of endometrial carcinoma.
Nature 497: 67-73 (2013)
PM ID: 23636398 PMC3704730 [Available on 11/02/13] NIHMS458933 [Available on 11/02/13]
494: Cancer Genome Atlas Research Network
Genomic and epigenomic landscapes of adult de novo acute myeloid leukemia.
N Engl J Med 368: 2059-74 (2013)
PM ID: 23634996 PMC3767041 [Available on 11/30/13] NIHMS491910 [Available on 11/30/13]
495: Monda KL, Chen GK, Taylor KC, Palmer C, Edwards TL, Lange LA, Ng MC, Adeyemo AA, Allison MA, Bielak LF, Chen G, Graff M, Irvin MR, Rhie SK, Li G, Liu Y, Liu Y, Lu Y, Nalls MA, Sun YV, Wojczynski MK, Yanek LR, Aldrich MC, Ademola A, Amos CI, Bandera EV, Bock CH, Britton A, Broeckel U, Cai Q, Caporaso NE, Carlson CS, Carpten J, Casey G, Chen WM, Chen F, Chen YD, Chiang CW, Coetzee GA, Demerath E, Deming-Halverson SL, Driver RW, Dubbert P, Feitosa MF, Feng Y, Freedman BI, Gillanders EM, Gottesman O, Guo X, Haritunians T, Harris T, Harris CC, Hennis AJ, Hernandez DG, McNeill LH, Howard TD, Howard BV, Howard VJ, Johnson KC, Kang SJ, Keating BJ, Kolb S, Kuller LH, Kutlar A, Langefeld CD, Lettre G, Lohman K, Lotay V, Lyon H, Manson JE, Maixner W, Meng YA, Monroe KR, Morhason-Bello I, Murphy AB, Mychaleckyj JC, Nadukuru R, Nathanson KL, Nayak U, N'Diaye A, Nemesure B, Wu SY, Leske MC, Neslund-Dudas C, Neuhouser M, Nyante S, Ochs-Balcom H, Ogunniyi A, Ogundiran TO, Ojengbede O, Olopade OI, Palmer JR, Ruiz-Narvaez EA, Palmer ND, Press MF, Rampersaud E, Rasmussen-Torvik LJ, Rodriguez-Gil JL, Salako B, Schadt EE, Schwartz AG, Shriner DA, Siscovick D, Smith SB, Wassertheil-Smoller S, Speliotes EK, Spitz MR, Sucheston L, Taylor H, Tayo BO, Tucker MA, Van Den Berg DJ, Edwards DR, Wang Z, Wiencke JK, Winkler TW, Witte JS, Wrensch M, Wu X, Yang JJ, Levin AM, Young TR, Zakai NA, Cushman M, Zanetti KA, Zhao JH, Zhao W, Zheng Y, Zhou J, Ziegler RG, Zmuda JM, Fernandes JK, Gilkeson GS, Kamen DL, Hunt KJ, Spruill IJ, Ambrosone CB, Ambs S, Arnett DK, Atwood L, Becker DM, Berndt SI, Bernstein L, Blot WJ, Borecki IB, Bottinger EP, Bowden DW, Burke G, Chanock SJ, Cooper RS, Ding J, Duggan D, Evans MK, Fox C, Garvey WT, Bradfield JP, Hakonarson H, Grant SF, Hsing A, Chu L, Hu JJ, Huo D, Ingles SA, John EM, Jordan JM, Kabagambe EK, Kardia SL, Kittles RA, Goodman PJ, Klein EA, Kolonel LN, Le Marchand L, Liu S, McKnight B, Millikan RC, Mosley TH, Padhukasahasram B, Williams LK, Patel SR, Peters U, Pettaway CA, Peyser PA, Psaty BM, Redline S, Rotimi CN, Rybicki BA, Sale MM, Schreiner PJ, Signorello LB, Singleton AB, Stanford JL, Strom SS, Thun MJ, Vitolins M, Zheng W, Moore JH, Williams SM, Ketkar S, Zhu X, Zonderman AB, NABEC Consortium , UKBEC Consortium , BioBank Japan Project , AGEN Consortium , Kooperberg C, Papanicolaou GJ, Henderson BE, Reiner AP, Hirschhorn JN, Loos RJ, North KE, Haiman CA
A meta-analysis identifies new loci associated with body mass index in individuals of African ancestry.
Nat Genet 45: 690-6 (2013)
PM ID: 23583978 PMC3694490 NIHMS474899
496: Lin SJ, Foley J, Jiang TX, Yeh CY, Wu P, Foley A, Yen CM, Huang YC, Cheng HC, Chen CF, Reeder B, Jee SH, Widelitz RB, Chuong CM
Topology of feather melanocyte progenitor niche allows complex pigment patterns to emerge.
Science 340: 1442-5 (2013)
PM ID: 23618762
497: Rohira AD, Chen CY, Allen JR, Johnson DL
Covalent small ubiquitin-like modifier (SUMO) modification of Maf1 protein controls RNA polymerase III-dependent transcription repression.
J Biol Chem 288: 19288-95 (2013)
PM ID: 23673667 PMC3696699 [Available on 06/28/14]
498: Li C, Li A, Xing Y, Li M, Chan B, Ouyang R, Taketo MM, Kucherlapati R, Borok Z, Minoo P
Apc deficiency alters pulmonary epithelial cell fate and inhibits Nkx2.1 via triggering TGF-beta signaling.
Dev Biol 378: 13-24 (2013)
PM ID: 23562608 PMC3838671 NIHMS463440
499: Marconett CN, Zhou B, Rieger ME, Selamat SA, Dubourd M, Fang X, Lynch SK, Stueve TR, Siegmund KD, Berman BP, Borok Z, Laird-Offringa IA
Integrated transcriptomic and epigenomic analysis of primary human lung epithelial cell differentiation.
PLoS Genet 9: e1003513 (2013)
PM ID: 23818859 PMC3688557
500: He K, Xu T, Xu Y, Ring A, Kahn M, Goldkorn A
Cancer cells acquire a drug resistant, highly tumorigenic, cancer stem-like phenotype through modulation of the PI3K/Akt/β-catenin/CBP pathway.
Int J Cancer : (2013)
PM ID: 23784558
501: Gang EJ, Hsieh YT, Pham J, Zhao Y, Nguyen C, Huantes S, Park E, Naing K, Klemm L, Swaminathan S, Conway EM, Pelus LM, Crispino J, Mullighan CG, McMillan M, Müschen M, Kahn M, Kim YM
Small-molecule inhibition of CBP/catenin interactions eliminates drug-resistant clones in acute lymphoblastic leukemia.
Oncogene : (2013)
PM ID: 23728349
502: Li C, Li Y, He L, Agarwal AR, Zeng N, Cadenas E, Stiles BL
PI3K/AKT signaling regulates bioenergetics in immortalized hepatocytes.
Free Radic Biol Med 60: 29-40 (2013)
PM ID: 23376468 PMC3654039 [Available on 07/01/14] NIHMS441394 [Available on 07/01/14]
503: Schumacher FR, Wang Z, Skotheim RI, Koster R, Chung CC, Hildebrandt MA, Kratz CP, Bakken AC, Bishop DT, Cook MB, Erickson RL, Fosså SD, Greene MH, Jacobs KB, Kanetsky PA, Kolonel LN, Loud JT, Korde LA, Le Marchand L, Lewinger JP, Lothe RA, Pike MC, Rahman N, Rubertone MV, Schwartz SM, Siegmund KD, Skinner EC, Turnbull C, Van Den Berg DJ, Wu X, Yeager M, Nathanson KL, Chanock SJ, Cortessis VK, McGlynn KA
Testicular germ cell tumor susceptibility associated with the UCK2 locus on chromosome 1q23.
Hum Mol Genet 22: 2748-53 (2013)
PM ID: 23462292 PMC3674801
504: Wei Z, Gao F, Kim S, Yang H, Lyu J, An W, Wang K, Lu W
Klf4 organizes long-range chromosomal interactions with the oct4 locus in reprogramming and pluripotency.
Cell Stem Cell 13: 36-47 (2013)
PM ID: 23747203
505: Creighton CJ, Morgan M, Gunaratne PH, Wheeler DA, Gibbs RA, Robertson A, Chu A, Beroukhim R, Cibulskis K, Signoretti S, Vandin F, Wu HT, Raphael BJ, Verhaak RG, Tamboli P, Torres-Garcia W, Akbani R, Weinstein JN, Reuter V, Hsieh JJ, Brannon A, Hakimi A, Jacobsen A, Ciriello G, Reva B, Ricketts CJ, Linehan W, Stuart JM, Rathmell W, Shen H, Laird PW, Muzny D, Davis C, Morgan M, Xi L, Chang K, Kakkar N, Treviño LR, Benton S, Reid JG, Morton D, Doddapaneni H, Han Y, Lewis L, Dinh H, Kovar C, Zhu Y, Santibanez J, Wang M, Hale W, Kalra D, Creighton CJ, Wheeler DA, Gibbs RA, Getz G, Cibulskis K, Lawrence MS, Sougnez C, Carter SL, Sivachenko A, Lichtenstein L, Stewart C, Voet D, Fisher S, Gabriel SB, Lander E, Beroukhim R, Schumacher SE, Tabak B, Saksena G, Onofrio RC, Carter SL, Cherniack AD, Gentry J, Ardlie K, Sougnez C, Getz G, Gabriel SB, Meyerson M, Robertson A, Chu A, Chun HJ, Mungall AJ, Sipahimalani P, Stoll D, Ally A, Balasundaram M, Butterfield YS, Carlsen R, Carter C, Chuah E, Coope RJ, Dhalla N, Gorski S, Guin R, Hirst C, Hirst M, Holt RA, Lebovitz C, Lee D, Li HI, Mayo M, Moore RA, Pleasance E, Plettner P, Schein JE, Shafiei A, Slobodan JR, Tam A, Thiessen N, Varhol RJ, Wye N, Zhao Y, Birol I, Jones SJ, Marra MA, Auman JT, Tan D, Jones CD, Hoadley KA, Mieczkowski PA, Mose LE, Jefferys SR, Topal MD, Liquori C, Turman YJ, Shi Y, Waring S, Buda E, Walsh J, Wu J, Bodenheimer T, Hoyle AP, Simons JV, Soloway MG, Balu S, Parker JS, Hayes D, Perou CM, Kucherlapati R, Park P, Shen H, Triche T, Weisenberger DJ, Lai PH, Bootwalla MS, Maglinte DT, Mahurkar S, Berman BP, Van Den Berg DJ, Cope L, Baylin SB, Laird PW, Creighton CJ, Wheeler DA, Getz G, Noble MS, DiCara D, Zhang H, Cho J, Heiman DI, Gehlenborg N, Voet D, Mallard W, Lin P, Frazer S, Stojanov P, Liu Y, Zhou L, Kim J, Lawrence MS, Chin L, Vandin F, Wu HT, Raphael BJ, Benz C, Yau C, Reynolds SM, Shmulevich I, Verhaak RG, Torres-Garcia W, Vegesna R, Kim H, Zhang W, Cogdell D, Jonasch E, Ding Z, Lu Y, Akbani R, Zhang N, Unruh AK, Casasent TD, Wakefield C, Tsavachidou D, Chin L, Mills GB, Weinstein JN, Jacobsen A, Brannon R, Ciriello G, Schultz N, Hakimi A, Reva B, Antipin Y, Gao J, Cerami E, Gross B, Aksoy BA, Sinha R, Weinhold N, Sumer S, Taylor BS, Shen R, Ostrovnaya I, Hsieh JJ, Berger MF, Ladanyi M, Sander C, Fei SS, Stout A, Spellman PT, Rubin DL, Liu TT, Stuart JM, Ng S, Paull EO, Carlin D, Goldstein T, Waltman P, Ellrott K, Zhu J, Haussler D, Gunaratne PH, Xiao W, Shelton C, Gardner J, Penny R, Sherman M, Mallery D, Morris S, Paulauskis J, Burnett K, Shelton T, Signoretti S, Kaelin WG, Choueiri T, Atkins MB, Penny R, Burnett K, Mallery D, Curley E, Tickoo S, Reuter V, Rathmell W, Thorne L, Boice L, Huang M, Fisher JC, Linehan WM, Vocke CD, Peterson J, Worrell R, Merino MJ, Schmidt LS, Tamboli P, Czerniak BA, Aldape KD, Wood CG, Boyd J, Weaver J, Iacocca MV, Petrelli N, Witkin G, Brown J, Czerwinski C, Huelsenbeck-Dill L, Rabeno B, Myers J, Morrison C, Bergsten J, Eckman J, Harr J, Smith C, Tucker K, Zach LA, Bshara W, Gaudioso C, Morrison C, Dhir R, Maranchie J, Nelson J, Parwani A, Potapova O, Fedosenko K, Cheville JC, Thompson RH, Signoretti S, Kaelin WG, Atkins MB, Tickoo S, Reuter V, Linehan WM, Vocke CD, Peterson J, Merino MJ, Schmidt LS, Tamboli P, Mosquera JM, Rubin MA, Blute ML, Rathmell W, Pihl T, Jensen M, Sfeir R, Kahn A, Chu A, Kothiyal P, Snyder E, Pontius J, Ayala B, Backus M, Walton J, Baboud J, Berton D, Nicholls M, Srinivasan D, Raman R, Girshik S, Kigonya P, Alonso S, Sanbhadti R, Barletta S, Pot D, Sheth M, Demchok JA, Davidsen T, Wang Z, Yang L, Tarnuzzer RW, Zhang J, Eley G, Ferguson ML, Mills Shaw KR, Guyer MS, Ozenberger BA, Sofia HJ, Cancer Genome Atlas Research Network
Comprehensive molecular characterization of clear cell renal cell carcinoma.
Nature 499: 43-9 (2013)
PM ID: 23792563 PMC3771322 NIHMS472502
506: Lai X, Zhang C, Wang J, Wang C, Lan X, Zhang C, Lei C, Chen H
mRNA expression pattern and association study with growth traits of bovine vaspin gene.
Mol Biol Rep 40: 4499-505 (2013)
PM ID: 23657594
507: Páez D, Gerger A, Zhang W, Yang D, Labonte MJ, Benhaim L, Kahn M, Lenz F, Lenz C, Ning Y, Wakatsuki T, Loupakis F, Lenz HJ
Association of common gene variants in the WNT/β-catenin pathway with colon cancer recurrence.
Pharmacogenomics J : (2013)
PM ID: 23817222
508: Blakeley BD, Shattuck J, Coates MB, Tran E, Laird-Offringa IA, McNaughton BR
Analysis of Protein-RNA Complexes Involving a RNA Recognition Motif Engineered To Bind Hairpins with Seven- and Eight-Nucleotide Loops.
Biochemistry : (2013)
PM ID: 23806102
509: Choi IS, Yu K, Kim J, De Guzman E, Weisenberger DJ, Oghamian S, Kim HJ, Lee KH, Carroll C, Trinh BN, Kim M, Houshdaran S, Laird PW, Jones PA, Warburton D, Liang G, Koh CJ
Alterations in deoxyribonucleic acid (DNA) methylation patterns of Calca, Timp3, Mmp2, and Igf2r are associated with chronic cystitis in a cyclophosphamide-induced mouse model.
Urology 82: 253.e9-15 (2013)
PM ID: 23806407 PMC3697025 NIHMS470243
510: Wang K, Kim C, Bradfield J, Guo Y, Toskala E, Otieno FG, Hou C, Thomas K, Cardinale C, Lyon GL, Golhar R, Hakonarson H
Whole-genome DNA/RNA sequencing identifies truncating mutations in RBCK1 in a novel Mendelian disease with neuromuscular and cardiac involvement.
Genome Med 5: 67 (2013)
PM ID: 23889995
511: Xie M, Hong C, Zhang B, Lowdon RF, Xing X, Li D, Zhou X, Lee HJ, Maire CL, Ligon KL, Gascard P, Sigaroudinia M, Tlsty TD, Kadlecek T, Weiss A, O'Geen H, Farnham PJ, Madden PA, Mungall AJ, Tam A, Kamoh B, Cho S, Moore R, Hirst M, Marra MA, Costello JF, Wang T
DNA hypomethylation within specific transposable element families associates with tissue-specific enhancer landscape.
Nat Genet 45: 836-41 (2013)
PM ID: 23708189 PMC3695047 [Available on 11/26/13] NIHMS475505 [Available on 11/26/13]
512: Esposito F, Di Rocco F, Zada G, Cinalli G, Schroeder HW, Mallucci C, Cavallo LM, Decq P, Chiaromonte C, Cappabianca P
Intraventricular and Skull Base NeuroEndoscopy in 2012: A Global Survey of Usage Patterns and the role of intraoperative neuronavigation.
World Neurosurg : (2013)
PM ID: 23851232
513: Zeng N, Yang KT, Bayan JA, He L, Aggarwal R, Stiles JW, Hou X, Medina V, Abad D, Palian BM, Al-Abdullah I, Kandeel F, Johnson DL, Stiles BL
PTEN controls β-cell regeneration in aged mice by regulating cell cycle inhibitor p16(ink4a.)
Aging Cell : (2013)
PM ID: 23826727
514: Schade B, Lesurf R, Sanguin-Gendreau V, Bui T, Deblois G, O'Toole SA, Millar EK, Zardawi SJ, Lopez-Knowles E, Sutherland RL, Giguère V, Kahn M, Hallett M, Muller WJ
β-Catenin signaling is a critical event in ErbB2-mediated mammary tumor progression.
Cancer Res 73: 4474-87 (2013)
PM ID: 23720052
515: Costa MA, Rommer E, Peric M, Nguyen TJ, Shahabi A, Davis GB, Vidar EN, Chan LS, Wong AK
Incidence of surgical-site infection is not affected by method of immediate breast reconstruction.
Plast Reconstr Surg 132: 20e-9e (2013)
PM ID: 23806951
516: Yu EJ, Kim SH, Kim MJ, Seo WY, Song KA, Kang MS, Yang CK, Stallcup MR, Kim JH
SUMOylation of ZFP282 potentiates its positive effect on estrogen signaling in breast tumorigenesis.
Oncogene 32: 4160-8 (2013)
PM ID: 22986521
517: Fazlollahi F, Kim YH, Sipos A, Hamm-Alvarez SF, Borok Z, Kim KJ, Crandall ED
Nanoparticle translocation across mouse alveolar epithelial cell monolayers: species-specific mechanisms.
Nanomedicine 9: 786-94 (2013)
PM ID: 23454523 PMC3702651 NIHMS448182
518: Samadder NJ, Vierkant RA, Tillmans LS, Wang AH, Weisenberger DJ, Laird PW, Lynch CF, Anderson KE, French AJ, Haile RW, Potter JD, Slager SL, Smyrk TC, Thibodeau SN, Cerhan JR, Limburg PJ
Associations between colorectal cancer molecular markers and pathways with clinicopathologic features in older women.
Gastroenterology 145: 348-56.e1-2 (2013)
PM ID: 23665275 PMC3772766 [Available on 08/01/14] NIHMS477695 [Available on 08/01/14]
519: Law MJ, Lee DS, Lee CS, Anglim PP, Haworth IS, Laird-Offringa IA
The role of the C-terminal helix of U1A protein in the interaction with U1hpII RNA.
Nucleic Acids Res 41: 7092-100 (2013)
PM ID: 23703211 PMC3737524
520: Wei Z, Huang D, Gao F, Chang WH, An W, Coetzee GA, Wang K, Lu W
Biological implications and regulatory mechanisms of long-range chromosomal interactions.
J Biol Chem 288: 22369-77 (2013)
PM ID: 23779110
521: Gao F, Ling C, Shi L, Commins D, Zada G, Mack WJ, Wang K
Inversion-mediated gene fusions involving NAB2-STAT6 in an unusual malignant meningioma.
Br J Cancer 109: 1051-5 (2013)
PM ID: 23860521 PMC3749567 [Available on 08/20/14]
522: Zada G, Tirosh A, Huang AP, Laws ER, Woodmansee WW
The postoperative cortisol stress response following transsphenoidal pituitary surgery: a potential screening method for assessing preserved pituitary function.
Pituitary 16: 319-25 (2013)
PM ID: 22915289
523: Yan HX, Wu HP, Zhang HL, Ashton C, Tong C, Wu J, Qian QJ, Wang HY, Ying QL
DNA damage-induced sustained p53 activation contributes to inflammation-associated hepatocarcinogenesis in rats.
Oncogene 32: 4565-71 (2013)
PM ID: 23069657
524: Su SF, Chang YW, Andreu-Vieyra C, Fang JY, Yang Z, Han B, Lee AS, Liang G
miR-30d, miR-181a and miR-199a-5p cooperatively suppress the endoplasmic reticulum chaperone and signaling regulator GRP78 in cancer.
Oncogene 32: 4694-701 (2013)
PM ID: 23085757
525: Zhang B, Zhou Y, Lin N, Lowdon RF, Hong C, Nagarajan RP, Cheng JB, Li D, Stevens M, Lee HJ, Xing X, Zhou J, Sundaram V, Elliott G, Gu J, Shi T, Gascard P, Sigaroudinia M, Tlsty TD, Kadlecek T, Weiss A, O'Geen H, Farnham PJ, Maire CL, Ligon KL, Madden PA, Tam A, Moore R, Hirst M, Marra MA, Zhang B, Costello JF, Wang T
Functional DNA methylation differences between tissues, cell types, and across individuals discovered using the M&M algorithm.
Genome Res 23: 1522-40 (2013)
PM ID: 23804400 PMC3759728
526: Awad S, Kunhi M, Little GH, Bai Y, An W, Bers D, Kedes L, Poizat C
Nuclear CaMKII enhances histone H3 phosphorylation and remodels chromatin during cardiac hypertrophy.
Nucleic Acids Res 41: 7656-72 (2013)
PM ID: 23804765 PMC3763528
527: Zack TI, Schumacher SE, Carter SL, Cherniack AD, Saksena G, Tabak B, Lawrence MS, Zhang CZ, Wala J, Mermel CH, Sougnez C, Gabriel SB, Hernandez B, Shen H, Laird PW, Getz G, Meyerson M, Beroukhim R
Pan-cancer patterns of somatic copy number alteration.
Nat Genet 45: 1134-1140 (2013)
PM ID: 24071852
528: Taghva A, Attenello FJ, Zada G, Khalessi AA, Hsieh PC
Minimally invasive posterior atlantoaxial fusion: a cadaveric and clinical feasibility study.
World Neurosurg 80: 414-21 (2013)
PM ID: 22381857
529: Li WD, Jiao H, Wang K, Zhang CK, Glessner JT, Grant SF, Zhao H, Hakonarson H, Arlen Price R
A genome wide association study of plasma uric acid levels in obese cases and never-overweight controls.
Obesity (Silver Spring) 21: E490-4 (2013)
PM ID: 23703922 PMC3762924 NIHMS430476
530: Thomas JP, Davis-Dao C, Lewinger JP, Siegmund KD, Hamilton AS, Daneshmand S, Skinner EC, Thomas DC, Cortessis VK
Null association between histology of first and second primary malignancies in men with bilateral testicular germ cell tumors.
Am J Epidemiol 178: 1240-5 (2013)
PM ID: 23928263 PMC3792726
531: Hattori T, Taft JM, Swist KM, Luo H, Witt H, Slattery M, Koide A, Ruthenburg AJ, Krajewski K, Strahl BD, White KP, Farnham PJ, Zhao Y, Koide S
Recombinant antibodies to histone post-translational modifications.
Nat Methods 10: 992-5 (2013)
PM ID: 23955773 PMC3828030 NIHMS510849
532: Bateman LA, Zaro BW, Miller SM, Pratt MR
An alkyne-aspirin chemical reporter for the detection of aspirin-dependent protein modification in living cells.
J Am Chem Soc 135: 14568-73 (2013)
PM ID: 23998633
533: Chang K, Creighton CJ, Davis C, Donehower L, Drummond J, Wheeler D, Ally A, Balasundaram M, Birol I, Butterfield SN, Chu A, Chuah E, Chun HJ, Dhalla N, Guin R, Hirst M, Hirst C, Holt RA, Jones SJ, Lee D, Li HI, Marra MA, Mayo M, Moore RA, Mungall AJ, Robertson AG, Schein JE, Sipahimalani P, Tam A, Thiessen N, Varhol RJ, Beroukhim R, Bhatt AS, Brooks AN, Cherniack AD, Freeman SS, Gabriel SB, Helman E, Jung J, Meyerson M, Ojesina AI, Pedamallu CS, Saksena G, Schumacher SE, Tabak B, Zack T, Lander ES, Bristow CA, Hadjipanayis A, Haseley P, Kucherlapati R, Lee S, Lee E, Luquette LJ, Mahadeshwar HS, Pantazi A, Parfenov M, Park PJ, Protopopov A, Ren X, Santoso N, Seidman J, Seth S, Song X, Tang J, Xi R, Xu AW, Yang L, Zeng D, Auman JT, Balu S, Buda E, Fan C, Hoadley KA, Jones CD, Meng S, Mieczkowski PA, Parker JS, Perou CM, Roach J, Shi Y, Silva GO, Tan D, Veluvolu U, Waring S, Wilkerson MD, Wu J, Zhao W, Bodenheimer T, Hayes DN, Hoyle AP, Jeffreys SR, Mose LE, Simons JV, Soloway MG, Baylin SB, Berman BP, Bootwalla MS, Danilova L, Herman JG, Hinoue T, Laird PW, Rhie SK, Shen H, Triche T, Weisenberger DJ, Carter SL, Cibulskis K, Chin L, Zhang J, Getz G, Sougnez C, Wang M, Saksena G, Carter SL, Cibulskis K, Chin L, Zhang J, Getz G, Dinh H, Doddapaneni HV, Gibbs R, Gunaratne P, Han Y, Kalra D, Kovar C, Lewis L, Morgan M, Morton D, Muzny D, Reid J, Xi L, Cho J, DiCara D, Frazer S, Gehlenborg N, Heiman DI, Kim J, Lawrence MS, Lin P, Liu Y, Noble MS, Stojanov P, Voet D, Zhang H, Zou L, Stewart C, Bernard B, Bressler R, Eakin A, Iype L, Knijnenburg T, Kramer R, Kreisberg R, Leinonen K, Lin J, Liu Y, Miller M, Reynolds SM, Rovira H, Shmulevich I, Thorsson V, Yang D, Zhang W, Amin S, Wu CJ, Wu CC, Akbani R, Aldape K, Baggerly KA, Broom B, Casasent TD, Cleland J, Creighton C, Dodda D, Edgerton M, Han L, Herbrich SM, Ju Z, Kim H, Lerner S, Li J, Liang H, Liu W, Lorenzi PL, Lu Y, Melott J, Mills GB, Nguyen L, Su X, Verhaak R, Wang W, Weinstein JN, Wong A, Yang Y, Yao J, Yao R, Yoshihara K, Yuan Y, Yung AK, Zhang N, Zheng S, Ryan M, Kane DW, Aksoy BA, Ciriello G, Dresdner G, Gao J, Gross B, Jacobsen A, Kahles A, Ladanyi M, Lee W, Lehmann KV, Miller ML, Ramirez R, Rätsch G, Reva B, Sander C, Schultz N, Senbabaoglu Y, Shen R, Sinha R, Sumer SO, Sun Y, Taylor BS, Weinhold N, Fei S, Spellman P, Benz C, Carlin D, Cline M, Craft B, Ellrott K, Goldman M, Haussler D, Ma S, Ng S, Paull E, Radenbaugh A, Salama S, Sokolov A, Stuart JM, Swatloski T, Uzunangelov V, Waltman P, Yau C, Zhu J, Hamilton SR, Getz G, Sougnez C, Abbott S, Abbott R, Dees ND, Delehaunty K, Ding L, Dooling DJ, Eldred JM, Fronick CC, Fulton R, Fulton LL, Kalicki-Veizer J, Kanchi KL, Kandoth C, Koboldt DC, Larson DE, Ley TJ, Lin L, Lu C, Magrini VJ, Mardis ER, McLellan MD, McMichael JF, Miller CA, O'Laughlin M, Pohl C, Schmidt H, Smith SM, Walker J, Wallis JW, Wendl MC, Wilson RK, Wylie T, Zhang Q, Burton R, Jensen MA, Kahn A, Pihl T, Pot D, Wan Y, Levine DA, Black AD, Bowen J, Frick J, Gastier-Foster JM, Harper HA, Helsel C, Leraas KM, Lichtenberg TM, McAllister C, Ramirez NC, Sharpe S, Wise L, Zmuda E, Chanock SJ, Davidsen T, Demchok JA, Eley G, Felau I, Ozenberger BA, Sheth M, Sofia H, Staudt L, Tarnuzzer R, Wang Z, Yang L, Zhang J, Omberg L, Margolin A, Raphael BJ, Vandin F, Wu HT, Leiserson MD, Benz SC, Vaske CJ, Noushmehr H, Knijnenburg T, Wolf D, van 't Veer L, Collisson EA, Anastassiou D, Ou Yang TH, Lopez-Bigas N, Gonzalez-Perez A, Tamborero D, Xia Z, Li W, Cho DY, Przytycka T, Hamilton M, McGuire S, Nelander S, Johansson P, Jörnsten R, Kling T, Sanchez J, Cancer Genome Atlas Research Network , Weinstein JN, Collisson EA, Mills GB, Shaw KR, Ozenberger BA, Ellrott K, Shmulevich I, Sander C, Stuart JM
The Cancer Genome Atlas Pan-Cancer analysis project.
Nat Genet 45: 1113-20 (2013)
PM ID: 24071849 PMC3919969 NIHMS549280
534: Michels KB, Binder AM, Dedeurwaerder S, Epstein CB, Greally JM, Gut I, Houseman EA, Izzi B, Kelsey KT, Meissner A, Milosavljevic A, Siegmund KD, Bock C, Irizarry RA
Recommendations for the design and analysis of epigenome-wide association studies.
Nat Methods 10: 949-55 (2013)
PM ID: 24076989
535: Schjerven H, McLaughlin J, Arenzana TL, Frietze S, Cheng D, Wadsworth SE, Lawson GW, Bensinger SJ, Farnham PJ, Witte ON, Smale ST
Selective regulation of lymphopoiesis and leukemogenesis by individual zinc fingers of Ikaros.
Nat Immunol 14: 1073-83 (2013)
PM ID: 24013668 PMC3800053 NIHMS516116
536: Wilson IM, Vucic EA, Enfield KS, Thu KL, Zhang YA, Chari R, Lockwood WW, Radulovich N, Starczynowski DT, Banáth JP, Zhang M, Pusic A, Fuller M, Lonergan KM, Rowbotham D, Yee J, English JC, Buys TP, Selamat SA, Laird-Offringa IA, Liu P, Anderson M, You M, Tsao MS, Brown CJ, Bennewith KL, Macaulay CE, Karsan A, Gazdar AF, Lam S, Lam WL
EYA4 is inactivated biallelically at a high frequency in sporadic lung cancer and is associated with familial lung cancer risk.
Oncogene : (2013)
PM ID: 24096489
537: Morgan-Bathke M, Lin HH, Chibly AM, Zhang W, Sun X, Chen CH, Flodby P, Borok Z, Wu R, Arnett D, Klein RR, Ann DK, Limesand KH
Deletion of ATG5 shows a role of autophagy in salivary homeostatic control.
J Dent Res 92: 911-7 (2013)
PM ID: 23884556 PMC3775371
538: Abeywardana T, Lin YH, Rott R, Engelender S, Pratt MR
Site-specific differences in proteasome-dependent degradation of monoubiquitinated α-synuclein.
Chem Biol 20: 1207-13 (2013)
PM ID: 24210006 PMC3855323 NIHMS530153
539: Jeong KW, Andreu-Vieyra C, You JS, Jones PA, Stallcup MR
Establishment of active chromatin structure at enhancer elements by mixed-lineage leukemia 1 to initiate estrogen-dependent gene expression.
Nucleic Acids Res : (2013)
PM ID: 24288367
540: Wrangle J, Wang W, Koch A, Easwaran H, Mohammad HP, Vendetti F, Vancriekinge W, Demeyer T, Du Z, Parsana P, Rodgers K, Yen RW, Zahnow CA, Taube JM, Brahmer JR, Tykodi SS, Easton K, Carvajal RD, Jones PA, Laird PW, Weisenberger DJ, Tsai S, Juergens RA, Topalian SL, Rudin CM, Brock MV, Pardoll D, Baylin SB
Alterations of immune response of Non-Small Cell Lung Cancer with Azacytidine.
Oncotarget 4: 2067-79 (2013)
PM ID: 24162015 PMC3875770
541: Tam KW, Zhang W, Soh J, Stastny V, Chen M, Sun H, Thu K, Rios JJ, Yang C, Marconett CN, Selamat SA, Laird-Offringa IA, Taguchi A, Hanash S, Shames D, Ma X, Zhang MQ, Lam WL, Gazdar A
CDKN2A/p16 inactivation mechanisms and their relationship to smoke exposure and molecular features in non-small-cell lung cancer.
J Thorac Oncol 8: 1378-88 (2013)
PM ID: 24077454
542: Kim K, Kim JM, Kim JS, Choi J, Lee YS, Neamati N, Song JS, Heo K, An W
VprBP has intrinsic kinase activity targeting histone H2A and represses gene transcription.
Mol Cell 52: 459-67 (2013)
PM ID: 24140421 PMC3851289 NIHMS531474
543: Blattler A, Farnham PJ
Cross-talk between site-specific transcription factors and DNA methylation states.
J Biol Chem 288: 34287-94 (2013)
PM ID: 24151070 PMC3843044
544: Kim TM, Laird PW, Park PJ
The landscape of microsatellite instability in colorectal and endometrial cancer genomes.
Cell 155: 858-68 (2013)
PM ID: 24209623 PMC3871995 NIHMS537460
545: Trotta AP, Need EF, Selth LA, Chopra S, Pinnock CB, Leach DA, Coetzee GA, Butler LM, Tilley WD, Buchanan G
Knockdown of the cochaperone SGTA results in the suppression of androgen and PI3K/Akt signaling and inhibition of prostate cancer cell proliferation.
Int J Cancer 133: 2812-23 (2013)
PM ID: 23740762
546: Luo B, Tseng CC, Adams GB, Lee AS
Deficiency of GRP94 in the hematopoietic system alters proliferation regulators in hematopoietic stem cells.
Stem Cells Dev 22: 3062-73 (2013)
PM ID: 23859598 PMC3856911
547: Liu R, Li X, Gao W, Zhou Y, Wey S, Mitra SK, Krasnoperov V, Dong D, Liu S, Li D, Zhu G, Louie S, Conti PS, Li Z, Lee AS, Gill PS
Monoclonal antibody against cell surface GRP78 as a novel agent in suppressing PI3K/AKT signaling, tumor growth, and metastasis.
Clin Cancer Res 19: 6802-11 (2013)
PM ID: 24048331
548: Chen GK, Chang X, Curtis C, Wang K
Precise inference of copy number alterations in tumor samples from SNP arrays.
Bioinformatics 29: 2964-70 (2013)
PM ID: 24021380 PMC3834792
549: Pedersen JS, Valen E, Vargas Velazquez AM, Parker BJ, Rasmussen M, Lindgreen S, Lilje B, Tobin DJ, Kelly TK, Vang S, Andersson R, Jones PA, Hoover CA, Tikhonov A, Prokhortchouk E, Rubin EM, Sandelin A, Gilbert MT, Krogh A, Willerslev E, Orlando L
Genome-wide nucleosome map and cytosine methylation levels of an ancient human genome.
Genome Res : (2013)
PM ID: 24299735
550: Kim K, Lee B, Kim J, Choi J, Kim JM, Xiong Y, Roeder RG, An W
Linker Histone H1.2 Cooperates with Cul4A and PAF1 to Drive H4K31 Ubiquitylation-Mediated Transactivation.
Cell Rep 5: 1690-703 (2013)
PM ID: 24360965 PMC3901356 NIHMS545033
551: Saito Y, Saito H, Liang G, Friedman JM
Epigenetic Alterations and MicroRNA Misexpression in Cancer and Autoimmune Diseases: a Critical Review.
Clin Rev Allergy Immunol : (2013)
PM ID: 24362548
552: Biancolella M, K Fortini B, Tring S, Plummer SJ, Mendoza-Fandino GA, Hartiala J, Hitchler MJ, Yan C, Schumacher FR, Conti DV, Edlund CK, Noushmehr H, Coetzee SG, Bresalier RS, Ahnen DJ, Barry EL, Berman BP, Rice JC, Coetzee GA, Casey G
Identification and characterization of functional risk variants for colorectal cancer mapping to chromosome 11q23.1.
Hum Mol Genet : (2013)
PM ID: 24256810
553: Hakimi AA, Furberg H, Zabor EC, Jacobsen A, Schultz N, Ciriello G, Mikklineni N, Fiegoli B, Kim PH, Voss MH, Shen H, Laird PW, Sander C, Reuter VE, Motzer RJ, Hsieh JJ, Russo P
An epidemiologic and genomic investigation into the obesity paradox in renal cell carcinoma.
J Natl Cancer Inst 105: 1862-70 (2013)
PM ID: 24285872 PMC3866155