Biostatistics Core Services





Statisticians who are members of the Biostatistics Core are available to provide statistical support to clinical, basic science, and cancer cause and prevention investigators. This support may range from simple advice, to participating in the design of the research project, to carrying out aspects of the data management and statistical analysis of a project. The level of support depends on the scale of the project, the support staff available, and the expertise of the investigator. The statisticians in this Core work with members of the Clinical Investigations Support Office (CISO) by participating in the planning, monitoring, and analysis of in-house clinical trials approved by the Clinical Investigations Committee (CIC). They adapt and incorporate innovations in statistical and clinical trials methodology into the design and analysis of cancer research studies.

Priorities: Initial, short-term consultation is available to all Cancer Center members. For studies that involve more of a statistician's time, priority is given to Cancer Center projects that have received peer-reviewed funding or are part of the research effort of a funded Cancer Center investigator, studies that are deemed critical to a specific Cancer Center program, and to clinical studies that are rated outstanding by the CIC, that have received CISO support, or that are reviewed and approved by the Cancer Therapy Evaluation Program of the NCI. There is no charge for Biostatistics Core support.

Staffing: The professional staff of the Biostatistics Core currently consists of five biostatisticians, who are faculty members of the Department of Preventive Medicine. These statisticians bring to the Cancer Center expertise in the area of cancer clinical trials (Drs. Susan Groshen, Dongyun Yang, and Richard Sposto), epidemiologic research (Drs. Pike and Buckley), and molecular epidemiology and genetics (Dr. Buckley). Dr. Groshen is involved primarily in clinical studies of adult patients; Dr. Buckley is involved primarily in the analysis of microarray data and in molecular epidemiology studies; Dr. Pike has expertise in the design of epidemiological studies as well as prevention investigations. Three master’s level statisticians support the professional staff of the Biostatistics Core.

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