University of Southern California
USC Norris Comprehensive Cancer Center
If you are a patient, please contact Keck Medical Center of USC at 800-USC-CARE.

Trial 3L-10-1


MR Techniques in the Evaluation of Hepatocellular Carcinoma: Gadoxetate.

Type: Diagnostic
Phase: Pilot
Status: Closed to Accrual with Ongoing Follow-up
Treatments:
Randomized: No
Defintions of terms and FAQ about clinical trials.
Trial Leaders/Researchers:  Gilbert Whang, M.D.
Other Trial Staff:  Andrea Contreras, Coordinator

Staff may log in to see study documents.


You may participate in this study if:
 Requirement
1CT features suggestive of HCC – For an arterially-enhancing lesion = / > 1 cm, but < 2 cm, all of the following criteria must be met: [1] Imaging features of a mass; [2] Wash-out on later phases of contrast administration; [3] At least 1 cm or more growth. For an arterially-enhancing leason = / > 2 cm, two of the following criteria must be met: [1] Imaging features of a mass; [2] Wash-out on later phases of contrast administration; [3] At least 1 cm or more growth.
2At least 18 years of age
3Able to tolerate a complete abdominal MR examination within 3 weeks of CT
4Signed an approved study-specific informed consent and HIPAA


You may not participate in this study if:
1Unable to undergo MRI due to intraocular metallic foreign body, pacemaker, or other contraindications including objects in the body which are deemed to be unsafe or notable to be assessed, or unable to undergo MRI within 3 weeks of CT
2Prior history of treatment of liver lesions
3Pregnancy
4Severe renal insufficiency – estimated glomerular filtration rate of < 30 cc/min
5Severe liver disease – Childs Class C Cirrhosis
6History of a previous reaction to contrast media, bronchial asthma, or allergic disorders
7Acute renal insufficiency of any severity due to the hepato-renal syndrome or in the peri-operative liver transplantation period



For further information on a study, please contact the Clinical Investigation Support Office at (323) 865-0451, or clinical.trials@med.usc.edu.

To schedule a consultation with the hospital, please call our New Patient Referrals Office at (323) 865-3111.