University of Southern California
USC Norris Comprehensive Cancer Center
If you are a patient, please contact Keck Medical Center of USC at 800-USC-CARE.

Trial 2L-10-1


Addario Lung Cancer Medical Institute (ALCMI) Collaborative Advanced Stage Tissue Lung Cancer (CASTLE) Network.

Type: Other
Phase: Not Applicable
Status: Open to Accrual
Treatments:
Randomized: No
Defintions of terms and FAQ about clinical trials.
Trial Leaders/Researchers:  Barbara Gitlitz, M.D.
Other Trial Staff:  Charlean Ketchens, R.N., Lagrimas Ilagan, D.M., Gina Tse, R.N., Eduardo Mejia, D.M.

Staff may log in to see study documents.


You may participate in this study if:
 Requirement
1M1A or B NSCLC or any stage SCLC with any number of prior therapies
2Planned systemic therapy
3At least 18 years of age
4Measurable or evaluable disease
5ECOG performance status of 0-2
6Expected survival at least 3 months
7Tumor specimens: [a] First Priority: availability of a minimum of a 1 X 10 mm core fresh frozen tumor from clinically indicated interventional procedures, with no systemic anti-cancer therapy or radiation to the biopsy site between collection of the biopsy and entry into the study; OR [b] Second Priority: availability of paraffin-embedded tumor at least 5 X 5 mm cross-sectional tumor area, with no systemic anti-cancer therapy or radiation to the biopsy site between collection of the biopsy and entry into the study; the collection of the paraffin-embedded tissues may have taken place up to 12 months prior to enrollment in CASTLE.
8Willingness to undergo all study collection procedures and sample analyses
9Provision of written informed consent for biospecimen storage, broad genetic and proteomic analysis of tumor and normal tissues, without restrictions, AND correlation with outcome data.


You may not participate in this study if:
1Other co-existing malignancies, except for basal cell carcinoma or cervical cancer in-situ
2Compromise of patient diagnosis or staging if tissue is harvested for research



For further information on a study, please contact the Clinical Investigation Support Office at (323) 865-0451, or clinical.trials@med.usc.edu.

To schedule a consultation with the hospital, please call our New Patient Referrals Office at (323) 865-3111.