Yves De Clerck, M.D. is the director of the Saban Research Institute of Childrens Hospital Los Angeles and a professor of pediatrics, biochemistry and molecular biology at the Keck School of Medicine of USC. He is also co-leader of the Tumor Microenvironment Program. Dr. Clerck is currently leading an NIH-funded research study on the mechanisms of tumor invasion and metastasis with a primary focus on neuroblastoma—the second most common solid tumor in children—and melanoma. He has been a researcher studying the role of the tumor microenvironment and cancer progression for more than 25 years. A native of Brussels, Belgium, he earned his bachelor’s degree, magna cum laude, from Notre Dame University in Belgium, and his medical degree, summa cum laude, from the Catholic University of Louvain, Belgium. He is a permanent member of the NIH Study Section of Tumor Progression and Metastasis, and serves on the Tumor Microenvironment Study Section in addition to other advisory boards at the NIH. He is currently on the editorial board of several scientific journals including Cancer Research, Clinical Cancer Research, Cancer Microenvironment, and the Journal of Cell Physiology. He has been an active participant in the American Association for Cancer Research (AACR) Scientist-Survivor Program for many years and has chaired two AACR sponsored conferences. Professional memberships include the AACR where he was the chair of the Local Liaison Committee for the 2005 Annual Meeting, the American Association for the Advancement of Science, and the American Society of Cell Biology. He is funded by three research grants from the NIH and has authored and co-authored more than 100 papers.