University of Southern California
USC Norris Comprehensive Cancer Center

Michael Lieber, M.D., Ph.D.

Photograph of Michael Lieber

Michael Lieber, M.D., Ph.D. is professor of pathology, biochemistry and molecular biology, molecular microbiology and biological sciences. He is the program leader of the Molecular Genetics Program. Dr. Lieber is currently conducting four research projects in chromosomal translocation development in human cells. His grant-funded projects include: • A National Institute of General Medical Sciences (NIGMS)-funded study of the mechanism of V(D)J recombination, and mistakes in this pathway result in many lymphoid translocations, as in T cell leukemias and lymphomas. • A NIGMS-funded study of the mechanism of class switch recombination, and mistakes in this pathway result in lymphoid translocations such as Burkitt's lymphoma. • A National Cancer Institute (NCI) Merit grant-funded study into additional causes of translocation in human malignancies. • An NCI grant to study how broken DNA ends are rejoined in a pathway called nonhomologous DNA end joining (NHEJ).