University of Southern California
USC Norris Comprehensive Cancer Center

Michael Lieber, M.D., Ph.D.

Photograph of Michael Lieber

Michael Lieber, M.D., Ph.D. is a Professor of Pathology, Biochemistry & Molecular Biology, Molecular Microbiology & Immunology, and Biological Sciences. He is the Co-Leader of the Molecular Genetics Program.

Dr. Lieber received his B.S., B.A. in Biochemistry/Biology from the University of Missouri, Columbia, Missouri in 1977. He received his doctorate in Biochemistry in 1981 and his medical degree in 1983 from the University of Chicago, Chicago, Illinois. He completed a residency in Pathology in 1986 and postdoctoral training in Biochemistry in 1989 at the National Institutes of Health, Bethesda, Maryland

Dr. Lieber is currently conducting four research projects in chromosomal translocation development in human cells. His grant funded projects include: a National Institute of General Medical Sciences (NIGMS) funded study of the mechanism of V(D)J recombination, and mistakes in this pathway result in many lymphoid translocations, as in T cell leukemias and lymphomas; an NIGMS funded study of the mechanism of class switch recombination, and mistakes in this pathway result in lymphoid translocations such as Burkitt's lymphoma; a National Cancer Institute (NCI) Merit grant funded study into additional causes of translocation in human malignancies; and an NCI grant to study how broken DNA ends are rejoined in a pathway called nonhomologous DNA end joining (NHEJ).