University of Southern California
USC Norris Comprehensive Cancer Center
If you are a patient, please contact Keck Medical Center of USC at 800-USC-CARE.

Trial ctsu/ACOSOGZ1071


A Phase II Study Evaluating the Role of Sentinel Lymph Node Surgery and Axillary Lymph Node Dissection Following Pre-Operative Chemotherapy in Women with Node Positive Breast Cancer (T0-4, N1-2, M0) at Initial Diagnosis.

Type: Treatment
Phase: Phase II
Status: Closed to Accrual with Ongoing Follow-up
Treatments: Chemotherapy: Systemic, Surgery
Randomized: No
Defintions of terms and FAQ about clinical trials.
Trial Leaders/Researchers:  Stephen Sener, M.D.
Other Trial Staff:  Kristy Watkins, R.N., Margarita Carranza, D.M., America Casillas-Lopez, Coordinator

Staff may log in to see study documents.


You may participate in this study if:
 Requirement
1Females with histologic diagnosis of invasive breast cancer, clinical stage T0-4 N1-2 M0 (excluding inflammatory breast cancer)
2FNA biopsy or core needle biopsy of an axillary node documenting nodal disease at time of diagnosis and prior to pre-operative chemotherapy.
3Pre-operative chemotherapy must be completed or planned for patient. Note: Patients enrolling on studies involving pre-operative chemotherapy (through cooperative groups or institutional studies) may be eligible for this study, provided sentinel node surgery prior to pre-operative chemotherapy was not required in the other studies.
4Age at least 18 years old.
5ECOG/Zubrod performance status 0-1.


You may not participate in this study if:
1Prior ipsilateral axillary surgery, such as excisional biopsy of lymph node(s) or treatment of hidradenitis.
2Prior SLN surgery/excisional lymph node biopsy for pathological confirmation of axillary status.



For further information on a study, please contact the Clinical Investigation Support Office at (323) 865-0451, or clinical.trials@med.usc.edu.

To schedule a consultation with the hospital, please call our New Patient Referrals Office at (323) 865-3111.